ablation system

Abstract

This invention relates to an ablation system, specifically to the field of ablation technology. The ablation system of this invention includes a cryoablation needle, which comprises an ablation needle body. The ablation needle body includes an inlet / outlet assembly. Through a moving mechanism or a matching cannula, the length of the ablation zone can be changed, allowing the same ablation needle body to accommodate ablation zones of various sizes. Therefore, the appropriate ablation zone size can be selected according to the size of the lesion. Thus, the cryoablation needle of this invention enables freezing and rewarming operations for lesions of various sizes, thereby reducing the number and types of cryoablation needles required and achieving cost reduction.

Description

[0001] This case is a divisional application of Chinese Patent CN202310621728.5, Cold and Hot Ablation Needle and Ablation System. Technical Field

[0002] This invention relates to the field of ablation technology, and particularly to a hot and cold ablation needle and ablation system. Background Technology

[0003] Cryoablation technology is increasingly becoming a major method for cancer treatment due to the low cost and easy availability of liquid nitrogen as the working medium. Current cryoablation techniques use ablation needles to deliver liquid nitrogen to the ablation zone, allowing heat exchange between the nitrogen and the corresponding lesion, thus freezing or warming the lesion. However, because lesions vary in size, ablation needles with various ablation zone sizes are generally designed to avoid overly large ablation zones that could damage normal tissue, or underly small ablation zones that would result in incomplete treatment. This leads to higher treatment costs. Summary of the Invention

[0004] The present invention provides a hot and cold ablation needle and an ablation system to solve at least one of the above-mentioned technical problems.

[0005] According to a first aspect of the present invention, a cold and hot ablation needle is provided, comprising an ablation needle body, the ablation needle body including an inlet and outlet assembly.

[0006] The inlet and outlet assembly is connected to a moving mechanism, which is configured to change the distance between the first inlet end and the first outlet end of the inlet and outlet assembly, thereby making the length of the ablation zone formed by the inlet and outlet assembly adjustable.

[0007] In one embodiment, the inlet and outlet assembly includes a first inlet pipe having a first inlet end, a first outlet pipe having a first outlet end, and a deformable pipe connected to the first outlet pipe, wherein the first inlet pipe passes through the first outlet pipe and the deformable pipe in sequence.

[0008] The moving mechanism is connected to the first return pipe and the deformable pipe respectively. When the moving mechanism moves, it can deform the deformable pipe, thereby driving the first return pipe to move relative to the first inlet pipe, so as to change the distance between the first return end and the first inlet end.

[0009] In one embodiment, the moving mechanism includes a vacuum moving cavity movably disposed in a connecting fixed sleeve, and the deformable tube is disposed in the vacuum moving cavity;

[0010] The inlet and outlet assembly further includes a second outlet pipe. The first outlet pipe and the second outlet pipe extend from different sides of the vacuum moving cavity into the vacuum moving cavity and are connected to the deformable tube. The distal end of the second outlet pipe passes through the vacuum moving cavity and the connecting fixing sleeve in sequence and is fixedly connected to the connecting fixing sleeve.

[0011] When the vacuum moving cavity moves in the connecting fixed sleeve along the direction close to and away from the second return pipe, it drives the first return pipe to move and compresses or stretches the deformable pipe.

[0012] In one embodiment, the moving mechanism further includes a drive member connected to the connecting fixed sleeve and the vacuum moving cavity respectively, the drive member being configured to drive the vacuum moving cavity to move within the connecting fixed sleeve by rotating or moving thereon.

[0013] In one embodiment, the driving member is rotatably connected to the connecting fixed sleeve and threadedly connected to the vacuum moving cavity. The driving member causes the vacuum moving cavity to move within the connecting fixed sleeve when it is screwed into or out of the vacuum moving cavity.

[0014] In one embodiment, a moving groove is provided on the outer side of the vacuum moving cavity. When the driving member drives the vacuum moving cavity to move in the connecting fixed sleeve, the end of the moving groove approaches or moves away from the second return pipe.

[0015] Wherein, the distance B between the end of the moving groove and the second return pipe is greater than the maximum relative displacement C between the driving member and the vacuum moving cavity, and the deformability A of the deformable tube is greater than the maximum relative displacement C between the driving member and the vacuum moving cavity.

[0016] In one embodiment, the driving member is engaged with the connecting fixing sleeve and fixedly connected to the vacuum moving cavity. The driving member moves the vacuum moving cavity within the connecting fixing sleeve by pulling or pushing the vacuum moving cavity.

[0017] In one embodiment, the vacuum moving cavity is provided with a cover, the first reflux pipe and the deformable pipe are connected through the cover, and the space between the cover and the proximal end of the vacuum moving cavity is a vacuum cavity.

[0018] In one embodiment, a replaceable needle is also included, with the proximal end of the needle disposed outside the first reflux tube and the distal end of the needle extending between the connecting fixing sleeve and the vacuum moving cavity and connected to the connecting fixing sleeve.

[0019] The working fluid flowing out from the first inlet end of the first inlet tube flows into the proximal side of the needle, then turns back and flows into the first return end of the first return tube.

[0020] In one embodiment, a sealing groove is provided on the outer wall of the vacuum moving cavity, and a sealing device is provided in the sealing groove. The distal end of the needle is movably and sealed to the vacuum moving cavity through the sealing device.

[0021] In one embodiment, the exterior of the drive member is further provided with a scale layer for indicating the relative displacement between the drive member and the vacuum moving cavity.

[0022] According to a second aspect of the present invention, the present invention provides an ablation system comprising the above-described hot and cold ablation needle, and further comprising a working fluid delivery device connected to the hot and cold ablation needle.

[0023] Compared with the prior art, the advantage of the present invention is that the length of the ablation zone can be changed by the moving mechanism or the cannula, so that the same ablation needle body can correspond to a variety of ablation zones of different sizes. Therefore, the appropriate size of the ablation zone can be selected according to the size of the lesion. Thus, the cold and hot ablation needle of the present invention can perform freezing and rewarming operations on lesions of various sizes, thereby reducing the number of models and types of cold and hot ablation needles and achieving the goal of reducing costs. Attached Figure Description

[0024] The invention will now be described in more detail with reference to embodiments and the accompanying drawings.

[0025] Figure 1 This is a cross-sectional view of the hot and cold ablation needle in Embodiment 1 of the present invention;

[0026] Figure 2 yes Figure 1 A magnified view at point M;

[0027] Figure 3 Is Figure 2 Based on this, a schematic diagram showing the change in the length of the ablation zone;

[0028] Figure 4 yes Figure 1 A cross-sectional view of the ablation needle body 1 shown;

[0029] Figure 5 yes Figure 4 A magnified view at point N;

[0030] Figure 6 yes Figure 4 Detailed diagram of China Mobile's organizational structure;

[0031] Figure 7 yes Figure 4Detailed diagram of the vacuum moving cavity;

[0032] Figure 8 This is a detailed view of the moving mechanism in another embodiment of the present invention;

[0033] Figure 9 This is a top view of the hot and cold ablation needle in an embodiment of the present invention;

[0034] Figure 10 yes Figure 1 Enlarged view at point P;

[0035] Figure 11 This is a detailed view of the connecting fixing sleeve in one embodiment of the present invention;

[0036] Figure 12 This is a detailed view of the connecting fixing sleeve in another embodiment of the present invention;

[0037] Figure 13a In one embodiment of the present invention, and Figure 11 A top view of the needle that mates with the connecting and fixing sleeve shown;

[0038] Figure 13b In another embodiment of the present invention, and Figure 12 Top view of the needle that mates with the connecting retaining sleeve shown.

[0039] Figure 14 This is a cross-sectional view of the hot and cold ablation needle in Embodiment 2 of the present invention;

[0040] Figure 15 yes Figure 14 A detailed view of the ablation needle body 1 shown;

[0041] Figure 16 yes Figure 14 The cross-sectional view of the mating sleeve shown;

[0042] Figure 17 yes Figure 14 A magnified view at point Q;

[0043] Figure 18 This is a cross-sectional view of the ablation system in Embodiment 3 of the present invention;

[0044] Figure 19 yes Figure 18 Detailed diagram of the quick-connect device shown;

[0045] Figure 20 yes Figure 19 The front view of the quick-connect connector shown;

[0046] Figure 21 yes Figure 19 The side view of the quick-connect connector shown;

[0047] Figure 22 yes Figure 19 The side view of the pressure ring shown;

[0048] Figure 23 yes Figure 19 The cross-sectional view of the pressure ring shown;

[0049] Figure 24 yes Figure 18 A magnified view at point H.

[0050] Figure label:

[0051] 100. Cold and hot ablation needle; 200. Working fluid transfer device; 300. Matching sleeve;

[0052] 1. Ablation needle body; 2. Needle tip;

[0053] 101. Driving component; 102. Connecting and fixing sleeve; 103. Inlet / outlet assembly; 104. Sealing device; 105. Connector; 150. Moving mechanism; 106. Ablation zone;

[0054] 1031. First inlet pipe; 1032. First return pipe; 1033. Deformable pipe; 1034. Second return pipe; 1035. First inlet end; 1036. First return end; 1037. Second inlet end; 1038. Second return end;

[0055] 151. Connecting pipe; 152. Cover; 153. Vacuum moving chamber; 154. Sealing groove; 155. Vacuum maintaining part; 156. Vacuum chamber; 157. Vacuum tube;

[0056] 1531, Moving groove; 1532, Internal thread; 1011, Slot; 1012, External thread; 1013, Scale layer; 1014, Elastic connector; 1015, Trigger button;

[0057] 1021. Fixed cone sleeve; 1022. Snap ball; 1023. Moving ring; 1024. Self-resetting spring; 1025. Snap ring; 1026. Sleeve body; 1027. Separator ring; 1028. Inclined mating surface; 1029. Connecting port;

[0058] 21. Needle tube; 22. Needle sheath; 221. Bead retainer groove; 222. Guide angle;

[0059] 210. Quick-connect device; 220. Second inlet tube; 230. Third return tube; 240. Pin; 250. Overlap; 260. Outer tube;

[0060] 201. Quick-connect coupling; 202. Pressure ring; 203. Compression spring; 204. Ball bearing; 205. Retaining ring;

[0061] 2011, First protrusion; 2012, First connector; 2013, Second connector; 2014, Mounting hole;

[0062] 2021, Second protrusion; 2022, Groove;

[0063] 301. Vacuum insulation sleeve; 302. Cone angle; 303. Connecting sleeve; 304. Connecting groove. Detailed Implementation

[0064] The invention will now be further described with reference to the accompanying drawings.

[0065] Example 1

[0066] like Figures 1-13a and Figure 13b As shown, according to the first aspect of this invention, a cold and hot ablation needle 100 is provided, which may be generally in the form of a bent tube or generally in the form of a straight tube. For example... Figure 1 In the example shown, the hot and cold ablation needle 100 is generally a bent tube structure, including an ablation needle body 1. The ablation needle body 1 includes an inlet / outlet assembly 103, which is connected to a moving mechanism 150. The moving mechanism 150 is configured to change the distance between the first inlet end 1035 and the first outlet end 1036 of the inlet / outlet assembly 103, thereby making the length of the ablation zone 106 formed by the inlet / outlet assembly 103 adjustable. Figure 2 and Figure 3 As shown, the first inlet end 1035 and the first return end 1036 are in different relative positions; wherein, Figure 2 An example is shown where the first return end 1036 is closer to the first inlet end 1035. Figure 3 An example is shown where the first return end 1036 is further away from the first inlet end 1035, therefore Figure 3 The length of the ablation zone 106 shown is greater than that of the ablation zone 106 shown. Figure 2 The ablation zone 106 shown is longer, thus enabling more thorough ablation of lesions with a larger area / range. Therefore, by changing the length of the ablation zone 106, the cryoablation needle 100 can adapt to different lesion sizes, thus broadening its application range.

[0067] The following will describe in detail how the moving mechanism 150 changes the distance between the first inlet end 1035 and the first return end 1036 of the inlet and return flow assembly 103.

[0068] Specifically, please combine Figure 4 , Figure 5 and Figure 6 The inlet and outlet assembly 103 includes a first inlet pipe 1031 having a first inlet end 1035 (e.g., Figure 5 As shown), the first return pipe 1032 with a first return end 1036 (as shown) Figure 5 (as shown) and the deformable tube 1033 connected to the first return tube 1032 (as shown) Figure 6 As shown, the first inlet pipe 1031 passes through the first return pipe 1032 and the deformable pipe 1033 in sequence.

[0069] The first inlet pipe 1031 is used to transport the working medium (e.g., liquid nitrogen for cryoablation or anhydrous ethanol for rewarming) from the working medium transfer device 200 described below to its first inlet end 1035. Since the first return end 1036 is an open end, the working medium can flow out from it to the ablation zone 106. The working medium in the ablation zone 106 can exchange heat with the lesion site (freezing or rewarming operation). The working medium that has completed heat exchange in the ablation zone 106 can enter the first return pipe 1032 from the first return end 1036 and return to the working medium transfer device 200 for collection along the deformable pipe 1033 and the second return pipe 1034. The inlet and return assembly 103 can also adopt, for example, the structural form of the first inlet pipe assembly and the first return pipe assembly disclosed in Chinese Patent CN110575242A.

[0070] like Figure 6 As shown, the moving mechanism 150 is connected to the first return pipe 1032 and the deformable pipe 1033 respectively, and the moving mechanism 150 can move relative to the first inlet pipe 1031. When the moving mechanism 150 moves relative to the first inlet pipe 1031, it causes the deformable pipe 1033 to deform, thereby driving the first return pipe 1032 to move relative to the first inlet pipe 1031, so as to change the distance between the first return end of the first return pipe 1032 and the first inlet end of the first inlet pipe 1031.

[0071] like Figure 6 As shown, the moving mechanism 150 includes a vacuum moving cavity 153 movably disposed in the connecting fixing sleeve 102, the vacuum moving cavity 153 moving within the connecting fixing sleeve 102. The inlet and outlet assembly 103 also includes a second outlet pipe 1034, wherein the first outlet pipe 1032 is along a first direction (e.g., Figure 6 The second return pipe 1034 extends along a second direction perpendicular to the first direction (as shown in the horizontal direction), and extends along a second direction perpendicular to the first direction (as shown in the horizontal direction). Figure 6Extending in the vertical direction (as shown), the first return pipe 1032 and the second return pipe 1034 extend from different sides of the vacuum moving cavity 153 into the vacuum moving cavity 153. For example, the first return pipe 1032 extends from the left side of the vacuum moving cavity 153 into the vacuum moving cavity 153, and the second return pipe 1034 extends from the lower side of the vacuum moving cavity 153 into the vacuum moving cavity 153. The first return pipe 1032 and the second return pipe 1034 are respectively connected to both ends of the deformable tube 1033 in the vacuum moving cavity 153.

[0072] As described above, the first return pipe 1032 extends along the first direction, and the second return pipe 1034 extends along the second direction perpendicular to the first direction. Therefore, the first return pipe 1032 and the second return pipe 1034 form a return path with a bend structure. Correspondingly, the first inlet pipe 1031 also forms an inlet path with a bend structure.

[0073] The distal end of the second return pipe 1034 passes sequentially through the vacuum moving cavity 153 and the connecting fixing sleeve 102, and is fixedly connected to the connecting fixing sleeve 102. Please refer to... Figure 11 and Figure 12 A connecting port 1029 is provided on the lower side of the connecting and fixing sleeve 102, which corresponds to the opening on the lower side of the vacuum moving cavity 153. The axis of the connecting port 1029 is perpendicular to the axis of the connecting and fixing sleeve 102 (sleeve body 1026). The distal end of the second return pipe 1034 passes through the opening on the lower side of the vacuum moving cavity 153 and extends into the connecting port 1029, so that the second return pipe 1034 and the connecting and fixing sleeve 102 can be fixed to each other.

[0074] Since the first inlet pipe 1031 extends within the first return pipe 1032, the deformable pipe 1033, and the second return pipe 1034, the first inlet pipe 1031, the second return pipe 1034, and the connecting fixing sleeve 102 are fixed elements, while the vacuum moving cavity 153 and the first return pipe 1032 are movable elements. That is, the vacuum moving cavity 153 and the first return pipe 1032 move relative to the first inlet pipe 1031 or the second return pipe 1034 within the connecting fixing sleeve 102. However, due to the second return pipe 1034... After the flow tube 1034 passes through the vacuum moving cavity 153 and the connecting fixing sleeve 102 in sequence, it is fixedly connected to the connecting fixing sleeve 102. Therefore, when the vacuum moving cavity 153 and the first return tube 1032 move, the deformable tube 1033 between the first return tube 1032 and the second return tube 1034 will be compressed (for example, when the vacuum moving cavity 153 moves towards the second return tube 1034) or stretched (for example, when the vacuum moving cavity 153 moves away from the second return tube 1034).

[0075] Please continue reading Figure 4 and Figure 6A connector 105 extending in the second direction is provided on one side of the connecting fixed sleeve 102. The second return pipe 1034 passes through the vacuum moving cavity 153, passes through the communication port 1029 of the connecting fixed sleeve 102, extends into the connector 105, and is fixed to the connector 105.

[0076] Furthermore, the moving mechanism 150 also includes a driving member 101 connected to the connecting fixed sleeve 102 and the vacuum moving cavity 153 respectively. The driving member 101 is disposed at the far end of the connecting fixed sleeve 102 and is configured to drive the vacuum moving cavity 153 to move within the connecting fixed sleeve 102 by rotating or moving it.

[0077] In one alternative implementation, such as Figure 6 As shown, the driving component 101 is rotatably connected to the connecting fixed sleeve 102 and threadedly connected to the vacuum moving cavity 153. When the driving component 101 screws into or out of the vacuum moving cavity 153, it causes the vacuum moving cavity 153 to move within the connecting fixed sleeve 102.

[0078] For example, a slot 1011 is provided on the outer wall of the driving component 101, and a retaining ring 1025 is provided in the connecting fixing sleeve 102. The retaining ring 1025 is disposed in the slot 1011, so that the driving component 101 can rotate relative to the connecting fixing sleeve 102. An external thread 1012 may also be provided on the outer wall of the driving component 101. The external thread 1012 is connected to the internal thread 1532 of the vacuum moving cavity 153. Therefore, when the driving component 101 rotates relative to the connecting fixing sleeve 102, the vacuum moving cavity 153 can move within the connecting fixing sleeve 102.

[0079] like Figure 7 As shown, a moving groove 1531 is provided on the outer side of the vacuum moving cavity 153. When the driving member 101 drives the vacuum moving cavity 153 to move within the connecting fixed sleeve 102, the end of the moving groove 1531 approaches or moves away from the second return pipe 1034. Since the second return pipe 1034 is a fixed element, when the vacuum moving cavity 153 moves relative to the second return pipe 1034, the moving groove 1531 on the outer side of the vacuum moving cavity 153 is the moving space between the vacuum moving cavity 153 and the second return pipe 1034. To avoid interference, the distance B between the end of the moving groove 1531 and the second return pipe 1034 (e.g., ...) is... Figure 7 (As shown) is greater than the maximum relative displacement C between the drive unit 101 and the vacuum moving cavity 153 (e.g.) Figure 1 As shown), and the deformability A of the deformable tube 1033 (as shown) Figure 7 (As shown) is greater than the maximum relative displacement C between the drive unit 101 and the vacuum moving cavity 153.

[0080] Understandably, one side of the deformable tube 1033 is connected to the bend of the second return tube 1034, and the other side is connected to the connecting tube 151 on the cap 152. Therefore, the range of the deformability A of the deformable tube 1033 is from the end of the connecting tube 151 to the bend of the second return tube 1034.

[0081] The deformable tube 1033 is made of a flexible, stretchable, and compressible material, or the deformable tube 1033 may be, for example, a stainless steel corrugated tube or other structural form.

[0082] In one alternative implementation, such as Figure 8 As shown, the drive unit 101 is engaged with the connecting fixed sleeve 102 and fixedly connected to the vacuum moving cavity 153 (e.g., welded). The drive unit 101 moves the vacuum moving cavity 153 in the connecting fixed sleeve 102 by pulling or pushing the vacuum moving cavity 153.

[0083] exist Figure 8 In the illustrated embodiment, the drive member 101 is further provided with an elastic connector 1014, which is connected to a trigger button 1015 on the outside of the drive member 101. When the drive member 101 pulls the vacuum moving cavity 153 to a designated position, pressing the trigger button 1015 will cause the elastic connector 1014 to pop out. The elastic connector 1014 will then abut against the end of the connecting fixing sleeve 102 near the drive member 101, thereby keeping the drive member 101 and the vacuum moving cavity 153 in the designated position. When it is necessary to change the position of the vacuum moving cavity 153, pressing the trigger button 1015 again will cause the elastic connector 1014 to retract, thereby allowing the vacuum moving cavity 153 to continue to be pulled or pushed to move.

[0084] The connection between the trigger button 1015 and the elastic connector 1014 can be made in various ways known in the prior art.

[0085] Further reading is available upon request. Figure 7 A cover 152 is provided in the vacuum moving cavity 153, and the first return pipe 1032 and the deformable pipe 1033 are connected through the cover 152. Specifically, a connecting pipe 151 is provided on the cover 152, and the first return pipe 1032 and the deformable pipe 1033 are located on both sides of the cover 152 and are respectively connected to both sides of the connecting pipe 151. The cavity between the cover 152 and the proximal end of the vacuum moving cavity 153 is a vacuum cavity 156. A vacuum pipe 157 is also provided outside the first return pipe 1032 (see [link to documentation]). Figure 5 The vacuum tube 157 is in vacuum communication with the vacuum chamber 156. The vacuum tube 157 and the non-ablation zone of the first return tube 1032 form a vacuum insulation section to facilitate operation. The vacuum chamber 156 is also provided with a vacuum maintenance section 155, which is used to maintain the vacuum characteristics of the vacuum chamber 156 and the vacuum tube 157.

[0086] Because of the vacuum chamber 156 in the vacuum moving cavity 153 and the vacuum tube 157 outside the first return tube 1032, when the vacuum moving cavity 153 moves, it moves together with the first return tube 1032, the vacuum tube 157, the vacuum chamber 156 and the cap 152 as a whole, thereby ensuring the vacuum characteristics of the vacuum chamber 156 and the vacuum tube 157, and thus ensuring the safe operation of the non-ablation zone of the ablation needle body 1.

[0087] In summary, in the moving mechanism 150 of the present invention, a deformable element (i.e., deformable tube 1033) is constructed between the movable element (i.e., the vacuum moving cavity 153 and the first return tube 1032) and the fixed element (i.e., the first inlet tube 1031, the second return tube 1034 and the connecting fixed sleeve 102), so that when the movable element moves, the shape of the deformable element is changed (compressed or stretched), thereby causing an axial relative displacement between the second return tube 1034 and the first inlet tube 1031, thereby achieving adjustable length of the ablation zone 106.

[0088] like Figure 1 and Figure 10 As shown, the cold and hot ablation needle of the present invention also includes a replaceable needle tip 2. The proximal side of the needle tip 2 is disposed outside the first return tube 1032, and the distal side of the needle tip 2 extends between the connecting fixing sleeve 102 and the vacuum moving cavity 153 and is connected to the connecting fixing sleeve 102. Therefore, the working fluid flowing out from the first inlet end 1035 of the first inlet tube 1031 flows into the proximal side of the needle tip 2 and then turns back and flows into the first return end 1036 of the first return tube 1032, thereby forming the ablation zone 106 (as described above) between the first inlet end 1035 of the first inlet tube 1031, the proximal side of the needle tip 2, and the first return end 1036 of the first return tube 1032. Figure 2 and Figure 3 As shown in the figure, it is used to perform ablation operations on lesions.

[0089] The needle 2 is also a fixed element, meaning the vacuum moving cavity 153 also moves relative to the needle 2. Therefore, the distance L between the first return end 1036 of the first return tube 1032 and the tip of the needle 2 is the adjustable distance (e.g., Figure 2 As shown, since the first inlet tube 1031 is a fixed component, the distance between the first inlet end 1035 of the first inlet tube 1031 and the tip of the needle 2 is a constant distance. Furthermore, the distance L between the first return end 1036 of the first return tube 1032 and the needle 2 can be adjusted up to a maximum of L+C (e.g., ...). Figure 3 As shown), C is the maximum relative displacement between the driving component 101 and the vacuum moving cavity 153 described above (e.g., as shown). Figure 1 (As shown).

[0090] like Figure 4 , Figure 6 and Figure 7 As shown, a sealing groove 154 is provided on the outer wall of the vacuum moving cavity 153, and a sealing device 104 (e.g., a sealing ring) is provided in the sealing groove 154. The distal end of the needle 2 is movably and sealed to the vacuum moving cavity 153 through the sealing device 104.

[0091] In some alternative implementations, the needle 2 forms a quick-plug connection with the connecting retaining sleeve 102.

[0092] Specifically, such as Figure 10 , Figure 11 and Figure 12 As shown, the connecting and fixing sleeve 102 includes a sleeve body 1026, a moving ring 1023, a self-resetting spring 1024, a fixing cone sleeve 1021, and a retaining bead 1022. The sleeve body 1026 is disposed outside the vacuum moving cavity 153, the moving ring 1023 is disposed outside the sleeve body 1026, and the fixing cone sleeve 1021 and the self-resetting spring 1024 are both disposed between the sleeve body 1026 and the moving ring 1023. A separating ring 1027 is provided on the sleeve body 1026, and the fixing cone sleeve 1021 and the self-resetting spring 1024 are respectively disposed on both sides of the separating ring 1027.

[0093] When the moving ring 1023 and the sleeve body 1026 move relative to each other, the self-restoring spring 1024 deforms. The sleeve body 1026 has a mounting hole, and a retaining ball 1022 is disposed in the mounting hole. A portion of the retaining ball 1022 extends beyond the mounting hole and contacts the fixed cone sleeve 1021. The fixed cone sleeve 1021 has an inclined mating surface 1028 that contacts the retaining ball 1022. The inclined mating surface 1028 can apply pressure to the retaining ball 1022, causing a portion of the retaining ball 1022 to extend beyond the mounting hole and into the interior of the sleeve body 1026.

[0094] When the moving ring 1023 moves, it can pull the fixed cone sleeve 1021 to move together, so that the retaining bead 1022 moves along the inclined mating surface 1028 until the retaining bead 1022 falls completely into the mounting hole. Then, the distal end of the needle 2 can be inserted between the sleeve body 1026 and the vacuum moving cavity 153. When the moving ring 1023 is released, the moving ring 1023 and the fixed cone sleeve 1021 return under the push of the self-resetting spring 1024. Then, the inclined mating surface 1028 applies pressure to the retaining bead 1022 again, so that a part of the retaining bead 1022 passes through the mounting hole and extends into the interior of the sleeve body 1026, so that it can be engaged with the mating part of the distal end of the needle 2, and the needle 2 can be engaged and fixedly connected with the connecting fixed sleeve 102.

[0095] in, Figure 11 and Figure 12 The difference in the illustrated embodiments is that, Figure 11 The self-resetting spring 1024 shown is located to the left of the separator ring 1027, the fixed cone sleeve 1021 is located to the right of the separator ring 1027, and the inclined mating surface 1028 is aligned with the axis of the sleeve body 1026 (as shown). Figure 11 The inclination angle between the inclined mating surface 1028 and the axis of the sleeve body 1026 (as shown by the midpoint line) is α1. Specifically, the inclination angle α1 between the inclined mating surface 1028 and the axis of the sleeve body 1026 starts from the axis of the sleeve body 1026 and rotates clockwise (as shown by the midpoint line). Figure 11 (As indicated by the middle arrow) The angle formed by the movement. Figure 12 The example shown is similar to Figure 11 Conversely, the self-resetting spring 1024 is located to the right of the separator ring 1027, the fixed cone sleeve 1021 is located to the left of the separator ring 1027, and the inclined mating surface 1028 is aligned with the axis of the sleeve body 1026 (e.g., ...). Figure 12 The inclination angle between the inclined mating surface 1028 and the axis of the sleeve body 1026 is α2. Specifically, the inclination angle α2 between the inclined mating surface 1028 and the axis of the sleeve body 1026 is α2. The inclined mating surface 1028 starts from the axis of the sleeve body 1026 and rotates counterclockwise (e.g., ...). Figure 12 The angle formed by the middle arrow.

[0096] In other words, Figure 11 In the embodiment shown, the closer to the proximal end, the larger the space formed between the inclined mating surface 1028 and the outer wall of the sleeve body 1026. Figure 12 In the embodiment shown, the closer to the distal end, the larger the space formed by the inclined mating surface 1028 and the outer wall of the sleeve body 1026.

[0097] Therefore, in response to Figure 11 In the illustrated embodiment, when installing the needle 2, the moving ring 1023 needs to be pulled distally. This allows the distal end of the needle 2 to lift the retaining bead 1022 and insert it into the cannula body 1026. After insertion, under the push of the self-resetting spring 1024, the moving ring 1023 and the fixed cone sleeve 1021 return, thereby pressing the retaining bead 1022 between the cannula body 1026 and the distal end of the needle 2, thus fixing the cannula body 1026 and the needle 2 together. When it is necessary to replace the needle 2, the moving ring 1023 needs to be pulled distally, causing the retaining bead 1022 to retract into the mounting hole, thereby separating the cannula body 1026 and the needle 2.

[0098] against Figure 12In the illustrated embodiment, there is no need to pull the moving ring 1023. When the distal end of the needle 2 is inserted into the cannula body 1026, the needle 2 can push the retaining bead 1022 to complete the insertion. After insertion, the pressurized working fluid delivered in the ablation needle body 1 generates positive pressure, which causes the moving ring 1023 and the fixed cone sleeve 1021 to tend to move towards the proximal end. This causes the inclined mating surface 1028 to press the retaining bead 1022 tightly between the cannula body 1026 and the needle 2, thereby achieving a reverse self-locking function. When it is necessary to replace the needle 2, pushing the moving ring 1023 towards the proximal end causes the retaining bead 1022 to retract into the mounting hole, thereby separating the cannula body 1026 and the needle 2. Therefore, it can be understood that in Figure 12 In the illustrated embodiment, the self-resetting spring 1024 can also act as a damper to improve the operator's feel.

[0099] like Figure 13a and Figure 13b As shown, the needle 2 includes a needle tube 21 and a needle sleeve 22 connected to the needle tube 21. Figure 13a The needle 2 shown is used with Figure 11 The connecting and fixing sleeve 102 in the embodiment shown cooperates with it. Figure 13b The needle 2 shown is used with Figure 12 The connecting fixing sleeve 102 in the illustrated embodiment is used in conjunction with it.

[0100] Specifically Figure 13a The outer wall of the needle sleeve 22 shown is provided with a bead-locking groove 221 extending circumferentially. As described above, after the distal end of the needle 2 is inserted into the cannula body 1026, the bead 1022 passes through the mounting hole of the fixed cone sleeve 1021 and is locked into the bead-locking groove 221, thereby fixing the needle 2 and the cannula body 1026 together. Therefore, through the cooperation of the bead-locking groove 221 and the bead 1022, the accidental separation of the needle 2 and the ablation needle body 1 during operation can be avoided.

[0101] In addition, the distal end of the needle sheath 22 is provided with a guide angle 222, combined with Figure 11 In the embodiment shown, when the distal end of the needle 2 is inserted into the sleeve body 1026, the guide angle 222 helps to lift the retaining bead 1022, so that the needle 2 can be inserted into the sleeve body 1026.

[0102] like Figure 13b As shown, the distal end of the needle sleeve 22 is provided with a guide angle 222, but the outer wall of the needle sleeve 22 does not have a bead retaining groove 221. Because Figure 12In the example shown, as described above, after insertion, the pressurized working fluid delivered within the ablation needle body 1 generates positive pressure, which causes the moving ring 1023 and the fixed cone sleeve 1021 to tend to move proximally. This causes the inclined mating surface 1028 to tightly press the retaining bead 1022 between the cannula body 1026 and the needle tip 2. In other words, Figure 12 The connecting and fixing sleeve 102 shown has a locking function, so there is no need to provide a locking bead groove 221 for locking on the outer wall of the needle sleeve 22.

[0103] Since the needle 2 comes into direct contact with the lesion, it is a single-use component. The quick-connect and quick-release connection between the needle 2 and the corresponding connecting sleeve 102 in the above embodiments allows for easy replacement of the needle 2. Because the ablation needle body 1 does not come into direct contact with the lesion, it can be reused after disinfection.

[0104] Since the length of the ablation zone 106 of the ablation needle body 1 is adjustable, it is not necessary to equip different models of ablation needles for different lesions. Instead, by adjusting the length of the ablation zone 106 and changing the needle 2, different sizes of lesion areas can be matched, thereby reducing the number of models and types of cold and hot ablation needles and helping to reduce costs.

[0105] In addition, such as Figure 9 As shown, the exterior of the drive member 101 is also provided with a scale layer 1013 for indicating the relative displacement between the drive member 101 and the vacuum moving cavity 153. By aligning the scale layer 1013 with the indicator line on the connecting fixing sleeve 102, the length of the corresponding ablation zone 106 can be obtained. The angle rotated by the drive member 101 and the relative displacement between the drive member 101 and the vacuum moving cavity 153 can be calculated using existing methods.

[0106] like Figure 1 As shown, the working fluid enters the first inlet pipe 1031 through the second inlet end 1037 and flows to the first inlet end 1035. The working fluid flows out from the first inlet end 1035 and turns back, entering the first return pipe 1032 from the first return end 1036, thereby forming the ablation zone 106. In the ablation zone 106, the working fluid undergoes heat exchange. After heat exchange, the working fluid flows sequentially through the first return pipe 1032, the deformable pipe 1033, and the second return pipe 1034, and flows out from the second return end 1038 of the second return pipe 1034, thus completing one cycle.

[0107] Example 2

[0108] The difference between this embodiment 2 and embodiment 1 is that this embodiment 2 does not use a moving mechanism 150 to change the length of the ablation zone 106, but instead uses a fitting sleeve 300 to change the length of the ablation zone 106. The fitting sleeve 300 is configured to change its fitting length with the inlet / outlet assembly 103, thereby making the length of the ablation zone 106 formed by the inlet / outlet assembly 103 adjustable.

[0109] like Figure 14 and Figure 15 As shown, the distal end of the fitting sleeve 300 is inserted into and connected to the ablation needle body 1, while the proximal end of the fitting sleeve 300 is fitted over the outside of the inlet / outlet assembly 103. By controlling the depth of the distal end of the fitting sleeve 300 inserted into the ablation needle body 1, the area of ​​the proximal end of the fitting sleeve 300 covering the inlet / outlet assembly 103 can be adjusted, so that the part of the inlet / outlet assembly 103 exposed outside the fitting sleeve 300, that is, the length L of the ablation zone 106 is adjustable.

[0110] like Figure 16 As shown, the fitting sleeve 300 includes a vacuum insulation sleeve 301 (with a length of E) and a connecting sleeve 303 connected thereto. The outer wall of the connecting sleeve 303 is provided with a connecting groove 304 extending circumferentially thereon. There are multiple connecting grooves 304, and the multiple connecting grooves 304 are spaced apart along their axial direction.

[0111] like Figure 15 As shown, the ablation needle body 1 may include the connecting and fixing sleeve 102 and the inlet / outlet assembly 103 described above. The vacuum tube described above is not disposed on the external side of the proximal end of the inlet / outlet assembly 103. Therefore... Figure 15 The proximal end of the inlet / outlet assembly 103 shown is a non-vacuum section (its length is D). A vacuum chamber 156 is provided on the distal end of the connecting fixing sleeve 102, which can maintain the vacuum characteristics of the distal end of the inlet / outlet assembly 103.

[0112] When the connecting sleeve 303 is inserted into the connecting fixing sleeve 102, the retaining bead 1022 in the connecting fixing sleeve 102 can be inserted into the corresponding connecting groove 304, thereby fixing the ablation needle body 1 to the mating sleeve 300.

[0113] Therefore, it can be understood that in this embodiment 2, the length L of the ablation zone 106 of the ablation needle body 1 is DE. By making the connecting groove 304 on the mating sleeve 300 closer to the proximal end cooperate with the retaining bead 1022, the length L of the ablation zone 106 can be increased. Conversely, by making the connecting groove 304 on the mating sleeve 300 closer to the distal end cooperate with the retaining bead 1022, the length L of the ablation zone 106 can be decreased.

[0114] In addition, a tapered angle 302 can be provided at the end of the sleeve 300 to facilitate needle insertion.

[0115] It should be noted that the differences between Embodiment 2 and Embodiment 1 have been described in detail above, and the similarities between the two will not be repeated.

[0116] Example 3

[0117] According to a second aspect of the present invention, the present invention also provides an ablation system, which includes the hot and cold ablation needle 100 described in Embodiments 1 and 2 above, and further includes a working fluid transfer device 200.

[0118] like Figure 18 The example shown illustrates an instance where the thermal ablation needle 100 of Embodiment 1 described above is connected to the working fluid transfer device 200. Specifically, the connector 105 of the thermal ablation needle 100 is connected to the working fluid transfer device 200 via a quick-connect device 210.

[0119] In some embodiments, the quick connection device 210 can adopt the structure of the connection fixing sleeve 102 in the above embodiments 1 and 2, that is, the connection between the cold and hot ablation needle 100 and the working fluid transmission device 200 can be the connection between the needle 2 and the connection fixing sleeve 102.

[0120] In other implementations, such as Figure 19 and Figure 20 As shown, the quick-connect device 210 includes a quick-connect connector 201, such as... Figure 19 As shown, the quick-connect device 210 also includes a pressure ring 202 sleeved on the outside of the quick-connect connector 201. A ball bearing 204 is also provided between the quick-connect connector 201 and the pressure ring 202, and the ball bearing 204 is pressed into and partially extends beyond the mounting hole 2014 of the quick-connect connector 201 (first connector 2012). Furthermore, a compression spring 203 and a retaining ring 205 are also provided between the quick-connect connector 201 and the pressure ring 202. Therefore, by rotating and pulling the pressure ring 202, the compression spring 203 is compressed, causing the ball bearing 204 to fall into the mounting hole, allowing the hot and cold ablation needle 100 to be inserted into the quick-connect device 210.

[0121] In some preferred embodiments, the quick-connect connector 201 includes a first connector 2012 and a second connector 2013 connected together, wherein the first connector 2012 is closer to the cryoablation needle 100. Figure 18 As shown, the outer diameter of the first connector 2012 is slightly smaller than the outer diameter of the second connector 2013.

[0122] like Figure 21 As shown, the outer wall of the second connector 2013 is provided with a plurality of first protrusions 2011 protruding outward therefrom, and the plurality of first protrusions 2011 are arranged at equal angles along the circumference of the quick connector 201. Figure 22 and Figure 23 As shown, the inner wall of the pressure ring 202 is provided with a plurality of second protrusions 2021 protruding inward, and grooves 2022 are formed between the plurality of second protrusions 2021. The plurality of second protrusions 2021 are arranged at equal angles along the circumference of the pressure ring 202. The second protrusions 2021 and the first protrusions 2011 are arranged in a one-to-one correspondence.

[0123] A ball bearing 204 is also provided between the first connector 2012 and the pressure ring 202, and the ball bearing 204 is pressed into the mounting hole 2014 of the first connector 2012.

[0124] When installing the thermal ablation needle 100, the pressure ring 202 is rotated simultaneously, causing the second protrusion 2021 to mate with the corresponding first protrusion 2011, thereby fixing the pressure ring 202 and the second connector 2013 in the current position, at which point the thermal ablation needle 100 can be inserted. Due to the engagement of the second protrusion 2021 and the first protrusion 2011, the quick-connect connector 201 remains in the unlocked state.

[0125] After the hot and cold ablation needle 100 is installed, rotate the pressure ring 202 again to disengage the second protrusion 2021 from the first protrusion 2011. Under the action of the pressure spring 203, the pressure ring 202 is pushed to the groove 2022 to engage with the first protrusion 2011, thereby pressing the ball bearing 204 back in and past the mounting hole. The ball bearing 204 can be locked between the hot and cold ablation needle 100 and the quick connector 201 to ensure a stable connection between the two.

[0126] Furthermore, the outer wall of the first protrusion 2011 and the second connector 2013 are connected by a rounded corner. This rounded corner connection reduces the friction caused by the compression spring 203, thus requiring less effort to rotate the pressure ring 202.

[0127] Therefore, by simply rotating the pressure ring 202, the second protrusion 2021 engages with the first protrusion 2011, thereby keeping the pressure ring 202 in the unlocked position to facilitate the connection of the thermal ablation needle 100. During this process, there is no need to apply force to the pressure ring 202 continuously (i.e., the user does not need to pull the pressure ring 202 continuously), which makes the installation of the thermal ablation needle 100 and the working fluid transfer device 200 more convenient and faster.

[0128] It is conceivable that the connecting and fixing sleeve 102 described in Embodiments 1 and 2 above can also adopt the structural form of the quick connection device 210 described above.

[0129] like Figure 24As shown, the working fluid transfer device 200 also includes a second inlet pipe 220 and a third return pipe 230 arranged side by side in the outer sleeve 260. The second inlet pipe 220 is connected to the pin 240 by an overlapping connection, as shown... Figure 24 As shown, the connection between the second inlet tube 220 and the pin 240 is an overlap portion 250.

[0130] Figure 24 The dotted line in the diagram shows the axis of the first inlet tube 1031, and the outer tube 260 is coaxially arranged with it, with their axes coinciding. However, the axis of the second inlet tube 220 is parallel to and not collinear with the axis of the pin 240. This is to minimize the overall size of the outer tube 260 while ensuring a certain safe distance between the second inlet tube 220 and the third return tube 230.

[0131] Pin 240 is inserted into the second inlet end 1037 of the first inlet tube 1031 (please refer to...) Figure 1 ), and is connected to the first inlet pipe 1031, and the second return end 1038 of the second return pipe 1034 (please refer to) Figure 1 It is connected to the third return pipe 230, so that the working fluid that has completed heat exchange in the hot and cold ablation needle 100 is transported to the recovery device through the third return pipe 230 or discharged into the environment.

[0132] Although the invention has been described with reference to preferred embodiments, various modifications can be made and components can be replaced with equivalents without departing from the scope of the invention. In particular, the technical features mentioned in the various embodiments can be combined in any manner as long as there is no structural conflict. The invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. An ablation system, characterized in that, It includes a hot and cold ablation needle (100) and a working fluid transfer device (200) connected to the hot and cold ablation needle (100). The thermal ablation needle (100) includes: The ablation needle body (1) includes an inlet / outlet assembly (103), which is connected to a moving mechanism (150). The moving mechanism (150) includes a vacuum moving cavity (153) movably disposed in a connecting fixing sleeve (102). The moving mechanism (150) is configured to change the distance between the first inlet end and the first outlet end of the inlet / outlet assembly (103), thereby making the length of the ablation zone (106) formed by the inlet / outlet assembly (103) adjustable. The inlet / outlet assembly (103) includes a first inlet tube (1031) with a first inlet end, a first outlet tube (1032) with a first outlet end, a deformable tube (1033) connected to the first outlet tube (1032), and a second outlet tube (1034). The first inlet tube (1031) passes through the first outlet tube (1032) and the deformable tube (1033) in sequence. A deformable tube (1033) is disposed in the vacuum moving cavity (153). The first return tube (1032) and the second return tube (1034) extend from different sides of the vacuum moving cavity (153) into the vacuum moving cavity (153) and are connected to the deformable tube (1033). The distal end of the second return tube (1034) passes through the vacuum moving cavity (153) and the connecting fixing sleeve (102) in sequence and is fixedly connected to the connecting fixing sleeve (102). When the vacuum moving cavity (153) moves in the connecting fixing sleeve (102) in directions close to and away from the second return tube (1034), it drives the first return tube (1032) to move and compress or stretch the deformable tube (1033), so that an axial relative displacement is generated between the first return tube (1032) and the first inlet tube (1031); and A replaceable needle (2) is provided with its proximal end located outside the first reflux tube (1032) of the inlet and outlet assembly (103), and its distal end extending between the connecting fixing sleeve (102) and the vacuum moving cavity (153) and connected to the connecting fixing sleeve (102). The connecting fixing sleeve (102) includes: A sleeve body (1026) is disposed outside the vacuum moving cavity (153), and a first mounting hole is provided on the sleeve body (1026). A movable ring (1023) is disposed outside the sleeve body (1026) and the movable ring (1023) and the sleeve body (1026) are movable relative to each other; A fixed cone sleeve (1021) is disposed between the sleeve body (1026) and the movable ring (1023); and A retaining bead (1022) is disposed in the first mounting hole, and a portion of the retaining bead (1022) extends beyond the first mounting hole and contacts the fixing cone sleeve (1021); A self-resetting spring (1024) is disposed between the sleeve body (1026) and the moving ring (1023); A separator ring (1027) is provided on the sleeve body (1026), the self-resetting spring (1024) is located on the right side of the separator ring (1027), and the fixed cone sleeve (1021) is located on the left side of the separator ring (1027); When the moving ring (1023) and the sleeve body (1026) move relative to each other, the self-restoring spring (1024) deforms; The fixed cone sleeve (1021) is provided with an inclined mating surface (1028) for contacting the retaining bead (1022). The inclined mating surface (1028) can apply pressure to the retaining bead (1022), so that a part of the retaining bead (1022) passes through the first mounting hole and extends into the interior of the sleeve body (1026). When the distal end of the needle (2) is inserted into the cannula body (1026), the needle (2) can push the locking bead (1022) to move to complete the insertion. After the insertion is in place, the pressurized working fluid delivered in the ablation needle body (1) generates positive pressure, causing the moving ring (1023) and the fixed cone sleeve (1021) to tend to move towards the distal end, and causing the inclined mating surface (1028) to press the locking bead (1022) between the cannula body (1026) and the needle (2), thereby achieving reverse self-locking.

2. The ablation system according to claim 1, characterized in that, The inclined mating surface (1028) and the axis of the cannula body (1026) have an inclined angle α2, such that the closer to the distal end of the needle (2), the larger the space formed between the inclined mating surface (1028) and the outer wall of the cannula body (1026).

3. The ablation system according to claim 1, characterized in that, The needle (2) includes a needle tube (21) and a needle sleeve (22) connected to the needle tube (21), and the distal end of the needle sleeve (22) is provided with a guide angle (222).

4. The ablation system according to any one of claims 1-3, characterized in that, The hot and cold ablation needle (100) and the working fluid transfer device (200) are connected by a quick connection device (210); The quick-connect device (210) is configured in the same structural form as the connecting fixing sleeve (102), or the quick-connect device (210) includes a quick-connect connector (201).

5. The ablation system according to claim 4, characterized in that, The quick-connect device (210) includes a quick-connect connector (201) and a pressure ring (202) sleeved on the outside of the quick-connect connector (201), the quick-connect connector (201) having a second mounting hole (2014). A ball bearing (204) is provided between the quick-connect connector (201) and the pressure ring (202). The ball bearing (204) can be pressed into the second mounting hole (2014) and can partially extend beyond the second mounting hole (2014).

6. The ablation system according to claim 5, characterized in that, A compression spring (203) and a retaining ring (205) are also provided between the quick-connect connector (201) and the pressure ring (202). When the pressure ring (202) is rotated and pulled, the compression spring (203) is compressed, so that the ball (204) falls into the second mounting hole (2014) so ​​that the hot and cold ablation needle (100) can be inserted into the quick-connect device (210).

7. The ablation system according to claim 6, characterized in that, The quick-connector (201) includes a first connector (2012) and a second connector (2013) connected together. The first connector (2012) is closer to the thermo-thermal ablation needle (100) than the second connector (2013), and the outer diameter of the first connector (2012) is smaller than the outer diameter of the second connector (2013). The ball bearing (204) is located between the first connector (2012) and the pressure ring (202), and the second mounting hole (2014) is provided on the first connector (2012).

8. The ablation system according to claim 7, characterized in that, The outer wall of the second connector (2013) is provided with a plurality of first protrusions (2011) protruding outward therefrom, and the plurality of first protrusions (2011) are arranged at equal angles along the circumference of the quick connector (201); The inner wall of the pressure ring (202) is provided with a plurality of second protrusions (2021) protruding inward thereto. The plurality of second protrusions (2021) are arranged at equal angles along the circumference of the pressure ring (202), and grooves (2022) are formed between the plurality of second protrusions (2021). The second protrusion (2021) and the first protrusion (2011) are provided in a one-to-one correspondence; When installing the thermal ablation needle (100), by simultaneously rotating the pressure ring (202), the second protrusion (2021) engages with the corresponding first protrusion (2011), thereby fixing the pressure ring (202) and the second connector (2013) in the current position. At this time, the thermal ablation needle (100) can be inserted. The engagement of the second protrusion (2021) with the first protrusion (2011) keeps the quick-connect connector (201) in the unlocked state. After the hot and cold ablation needle (100) is installed, rotate the pressure ring (202) again so that the second protrusion (2021) disengages from the first protrusion (2011). Under the action of the pressure spring (203), the pressure ring (202) is pushed to the groove (2022) to cooperate with the corresponding first protrusion (2011). The ball bearing (204) is pressed in again and passes through the second mounting hole (2014). The ball bearing (204) can be stuck between the hot and cold ablation needle (100) and the quick connector (201) to ensure a stable connection between the two.

9. The ablation system according to claim 8, characterized in that, The first protrusion (2011) and the outer wall of the second connector (2013) are connected by a rounded corner transition.

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