Fume hood, pharmaceutical preparation test monitoring method and related device
By grouping and monitoring reagents in drug preparation experiments in real time, the problems of disorderly reagent placement and operational violations were solved, thus achieving standardization and safety in the experimental process.
Patent Information
- Application Number
- CN202310881349.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-07-18
- Publication Date
- 2025-12-19
- Estimated Expiration
- 2043-07-18
AI Technical Summary
In drug preparation experiments, reagents are often placed haphazardly and operational violations are frequent, especially the failure to seal highly volatile or toxic reagents in a timely manner, which leads to safety hazards and operational inconvenience.
By acquiring reagent information, the reagents are grouped and their corresponding placement areas are displayed on the test bench. The reagent positions and sealing status are monitored in real time, and warnings are issued to correct any violations.
This effectively reduced the disorderly placement of reagents and operational violations, improving the safety and efficiency of the experimental process.
Smart Images

Figure CN117019812B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of medicine preparation, in particular to a fume hood, a medicine preparation test monitoring method and related equipment thereof. BACKGROUND
[0002] At present, when a medicine preparation test is performed, a fume hood is usually used for the test, and the fume hood generally comprises a cabinet body 1, a suction device and an exhaust port 2 arranged in the cabinet body 1, the cabinet body 1 is provided with a test window 3, the bottom of the test window 3 is provided with a test table 4, the side wall and / or the top of the test window 3 is provided with an air inlet 5, the suction device sucks air through the air inlet 5 and discharges the air through the exhaust port 2; when the test is performed, the required reagents and test equipment are placed on the test table 4 for the test, and the suction device is turned on to adsorb the waste gas generated during the test and discharge the waste gas to a waste gas treatment system through the exhaust port 2, so as to avoid the waste gas from scattering out of the test window 3. Figure 5
[0003] Sometimes, when a medicine preparation test is performed, a plurality of reagents need to be used, and a large amount of reagents are placed on the test table, which is easy to cause disorderly placement (for example, when an oxcarbazepine preparation test is performed, a total of 18 reagents such as o-nitrophenyl, ethyl formate and sodium methoxide need to be used, and after being placed on the test table, the medicine is placed in a very disorderly manner), which may cause the reagents to be knocked down by the operator when the reagents are taken, in addition, some reagents may have high volatility or toxicity, and the reagent bottle cap needs to be closed in time after the reagent is taken, but the operator may not close the reagent bottle cap in time due to laziness, thereby causing a large amount of reagent to volatilize; in order to reduce the occurrence of the above improper operation, a fume hood and a monitoring method capable of effectively monitoring the test process need to be sought. SUMMARY
[0004] The present application aims to provide a fume hood, a medicine preparation test monitoring method and related equipment thereof, which can effectively monitor the medicine preparation test process and is beneficial to reducing the occurrence of operation violations.
[0005] In a first aspect, the present application provides a medicine preparation test monitoring method applied to a fume hood, comprising the steps of:
[0006] A1. obtaining test information; the test information comprises reagent information of reagents required for a test;
[0007] A2. grouping the reagents according to the reagent information to obtain at least one reagent group;
[0008] A3. displaying a placement area corresponding to each reagent group on a test table according to the grouping result;
[0009] A4. Real-time monitoring of the test operation, and judging whether there is a violation of the operation based on the placement area and the grouping result; the violation of the operation includes a first violation of the operation indicating that the reagent placement position is incorrect, and a second violation of the operation indicating that the reagent bottle is not timely closed;
[0010] A5. When the violation of the operation occurs, a warning is issued.
[0011] After grouping the reagents required for the test, the placement area corresponding to each reagent group is displayed on the test bench for the corresponding reagent group to be placed, so as to guide the operator to orderly classify and place each reagent, reduce the situation that other reagents are knocked down when the operator takes the reagents due to the disorderly placement of the reagents, and timely issue a warning to remind the operator to correct, which can effectively monitor the drug preparation test process and is beneficial to reduce the occurrence of operation violations.
[0012] Preferably, the reagent information includes reagent identification information, volatility parameters and harmfulness parameters.
[0013] Preferably, step A2 includes:
[0014] According to the volatility parameters and the harmfulness parameters of each reagent, a harm index of each reagent is calculated;
[0015] The reagents are grouped according to the harm index.
[0016] The harm of each reagent to people is quantitatively analyzed through the harm index, and then the reagents are grouped according to the harm index, so as to place the placement area according to the harm of each reagent group to people in the subsequent process, so as to reduce the harm to people.
[0017] Preferably, step A3 includes:
[0018] According to the harm index of each reagent, an average harm index of each reagent group is calculated;
[0019] According to the number of reagents in each reagent group, the size of the corresponding placement area is determined;
[0020] According to the average harm index of each reagent group, the size of the corresponding placement area and the position of the preset operation area on the test bench, the position of each placement area is determined;
[0021] According to the position and size of each placement area, each placement area is displayed on the test bench.
[0022] The positions of the placement regions are determined according to the average harm index of each reagent group and the position of the preset operation region, so that the reagent with higher harm can be placed at a position farther from the preset operation region, thereby reducing the harm to the operator.
[0023] Preferably, the step of displaying each placement region on the test bench comprises:
[0024] Each placement region is displayed by an LED array on the test bench.
[0025] Preferably, step A4 comprises:
[0026] Real-time video information of the test bench is collected;
[0027] The video information is analyzed based on an image analysis method to obtain the real-time placement position of each reagent;
[0028] If the real-time placement position of at least one reagent is not in the corresponding placement region, it is determined that a first rule violation operation condition indicating incorrect reagent placement position occurs.
[0029] Further, step A4 further comprises:
[0030] The video information is analyzed based on an image analysis method to obtain the opening time of the reagent bottle of each reagent;
[0031] According to the volatility parameter and the harmfulness parameter of each reagent, the opening upper limit time of the reagent bottle of each reagent is obtained;
[0032] If the opening time of the reagent bottle of at least one reagent exceeds the corresponding opening upper limit time, it is determined that a second rule violation operation condition indicating that the reagent bottle is not timely closed occurs.
[0033] In a second aspect, the present application provides an electronic device, comprising a processor and a memory, wherein the memory stores a computer program executable by the processor, and when the processor executes the computer program, the steps of the pharmaceutical preparation test monitoring method described above are executed.
[0034] In a third aspect, the present application provides a computer readable storage medium, which stores a computer program, and when the computer program is executed by a processor, the steps of the pharmaceutical preparation test monitoring method described above are executed.
[0035] In a fourth aspect, the present application provides a fume hood, comprising a fume hood body provided with a test window and a test table at the bottom of the test window, a central controller, a camera, an LED array and an alarm device, the camera being arranged at the top of the test window, the LED array being arranged at the top of the test table, and the fume hood body, the camera, the LED array and the alarm device being electrically connected to the central controller.
[0036] The central controller is configured to:
[0037] obtain test information, wherein the test information comprises reagent information of reagents required for a test;
[0038] group the reagents according to the reagent information to obtain at least one reagent group;
[0039] control the LED array to display a placement area corresponding to each reagent group on the test table according to the grouping result;
[0040] monitor test operation in real time through the camera and determine whether a violation occurs based on the placement area and the grouping result, wherein the violation includes a first violation indicating incorrect placement of a reagent and a second violation indicating that a reagent bottle is not timely closed;
[0041] issue a warning through the alarm device when the violation occurs.
[0042] Beneficial effects: The fume hood, the drug preparation test monitoring method and the related equipment provided by the present application group the reagents required for a test and display a placement area corresponding to each reagent group on the test table for the corresponding reagent group to be placed, so as to guide the operator to orderly classify and place the reagents, reduce the situation that the operator knocks down other reagents when taking a reagent due to disordered placement of the reagents, monitor in real time whether the reagents are placed correctly and whether the reagent bottles are not timely closed during the test, and timely issue a warning to remind the operator to correct, which can effectively monitor the drug preparation test process and is conducive to reducing the occurrence of operation violations. BRIEF DESCRIPTION OF DRAWINGS
[0043] Figure 1 The flowchart of the drug preparation test monitoring method provided by the embodiment of the present application.
[0044] Figure 2 The structural schematic diagram of the fume hood provided by the embodiment of the present application.
[0045] Figure 3 The structural schematic diagram of the electronic device provided by the embodiment of the present application.
[0046] Figure 4 The equipment connection diagram of the fume hood provided by the embodiments of the present application.
[0047] Figure 5 The structural schematic diagram of the existing fume hood.
[0048] Label explanation: 1, cabinet body; 2, exhaust port; 3, test window; 4, test bench; 5, air inlet; 6, central controller; 7, camera; 8, LED array; 9, alarm device; 10, display; 11, air suction device; 301, processor; 302, memory; 303, communication bus. DETAILED DESCRIPTION
[0049] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only some of the embodiments of the present application, but not all the embodiments of the present application. The components of the embodiments of the present application described and shown in the drawings herein can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present application provided in the drawings is not intended to limit the scope of the claimed present application, but only represents selected embodiments of the present application. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present application.
[0050] It should be noted that: similar labels and letters represent similar items in the following drawings, therefore, once an item is defined in one drawing, it does not need to be further defined and explained in subsequent drawings. Meanwhile, in the description of the present application, the terms “first”, “second” and the like are only used to distinguish the description, and cannot be understood as indicating or implying relative importance.
[0051] Please refer to Figure 1 , Figure 1 The drug preparation test monitoring method in some embodiments of the present application is applied to a fume hood, and includes the steps of:
[0052] A1. Obtaining test information; the test information includes reagent information of reagents required for the test;
[0053] A2. Grouping the reagents according to the reagent information to obtain at least one reagent group;
[0054] A3. Displaying a placement area corresponding to each reagent group on the test bench according to the grouping result;
[0055] A4. Real-time monitoring of test operation, and judging whether there is a violation of operation based on the placement area and grouping results; the violation of operation includes a first violation of operation indicating that the reagent placement position is incorrect, and a second violation of operation indicating that the reagent bottle is not timely closed;
[0056] A5. When a violation of operation occurs, a warning is issued.
[0057] After grouping the reagents required for the test, the placement area corresponding to each reagent group is displayed on the test bench for the corresponding reagent group to be placed, so as to guide the operator to orderly classify and place each reagent, reduce the situation that the operator knocks down other reagents when taking the reagents due to disordered placement of the reagents, and timely issue a warning to remind the operator to correct (after being warned, the operator will pay more attention to the operation norm in the subsequent operation), which can effectively monitor the drug preparation test process and is conducive to reducing the occurrence of operation violations.
[0058] In some embodiments, the reagent information includes reagent identification information, volatility parameter and harmfulness parameter. The reagent identification information is information for identifying the reagent, which can be but is not limited to name, molecule or number, etc. The volatility parameter is a parameter quantitatively set in advance according to the volatility of the reagent (the specific setting rules can be determined according to actual needs), which is used to characterize the ease of reagent evaporation. The harmfulness parameter is a parameter quantitatively set in advance according to the toxicity, corrosivity, irritability and other characteristics of the reagent (the specific setting rules can be determined according to actual needs), which is used to characterize the harm degree of the reagent to the human body. The volatility parameter and the harmfulness parameter of the reagent can be obtained according to the reagent identification information.
[0059] The test information can be obtained by uploading by the test operator, or obtained by querying according to the test identification information. The test identification information can be but is not limited to test name or test number, etc. When querying the test information according to the test identification information, the test information can be obtained in a preset test information library (the test information library records the test information corresponding to various tests) according to the test identification information.
[0060] In some embodiments, all reagents in the laboratory can be pre-grouped (grouping can be performed according to actual needs) to obtain a plurality of first groups, and in step A2, the reagents required for the test belonging to the same first group are divided into the same reagent group. This way can realize fast grouping, but sometimes the reagents required for the test can be more and belong to different first groups, resulting in a large number of reagent groups and a large number of placement areas that need to be divided, which makes the reagent placement operation in the test process too cumbersome.
[0061] To this end, in some other embodiments, step A2 comprises:
[0062] According to the volatility parameter and the harmfulness parameter of each reagent, a hazard index of each reagent is calculated.
[0063] The reagents are grouped according to the hazard index.
[0064] The hazard of each reagent to human is quantitatively analyzed by the hazard index, and then the reagents are grouped according to the hazard index, so as to facilitate the subsequent setting of the placement area according to the hazard of each reagent group to human, so as to reduce the damage to human. In addition, reagents with similar hazard are grouped, which is conducive to avoiding the situation that the number of divided placement areas is too large, resulting in too cumbersome reagent placement operation in the test process.
[0065] In the case of the same harmfulness parameter, the greater the volatility parameter, the more volatile the reagent, and the higher the risk of causing harm to the operator. Therefore, compared with evaluating the harm of reagents to human only according to the harmfulness parameter, it is more scientific and reasonable to evaluate the harm of reagents to human by comprehensively considering the volatility parameter and the harmfulness parameter. Specifically, the sum or weighted sum (the specific weighting value can be set according to actual needs) of the volatility parameter and the harmfulness parameter can be calculated as the hazard index of the reagent, but it is not limited thereto.
[0066] Further, when the number of reagents in a reagent group is too large, the excessive reagents are placed in the same placement area, which is easy to cause other reagents to be knocked down when taking and placing reagents. Therefore, after the step of grouping the reagents according to the hazard index, the step of:
[0067] If there is a reagent group with a number of reagents exceeding a preset number threshold (which can be set according to actual needs), the reagent group with a number of reagents exceeding the preset number threshold is divided into at least two reagent groups, so that the number of reagents in all divided reagent groups does not exceed the preset number threshold.
[0068] In some embodiments, when the reagent group with a number of reagents exceeding the preset number threshold is divided into at least two reagent groups, the at least two reagent groups can be randomly divided.
[0069] In some other embodiments, when the reagent group with a number of reagents exceeding the preset number threshold is divided into at least two reagent groups, the reagents in the reagent group with a number of reagents exceeding the preset number threshold can be sorted according to the hazard index, and then the reagents in the reagent group are divided into at least two reagent groups according to the sorting result (for example, when divided into two groups, the first half of the reagents in the sorting is divided into a group, and the other half of the reagents is divided into another group).
[0070] In some embodiments, the test information further comprises the number of times each reagent is used; when the reagent groups whose number of reagents exceeds the preset number threshold are divided into at least two reagent groups, the reagents in the reagent groups whose number of reagents exceeds the preset number threshold can be sorted according to the number of times each reagent is used, and then the reagents in the reagent group are divided according to the sorting result to obtain at least two reagent groups. Thus, in the subsequent placement area position setting, the number of times each reagent is used can be considered, for example, under the same conditions, the placement area position of the reagent group with a larger average number of times of use can be closer to the operator, so as to facilitate the operator to take and place the reagents that need to be used multiple times, and improve the operation convenience.
[0071] Preferably, step A3 comprises:
[0072] A301. According to the hazard index of each reagent, the average hazard index of each reagent group is calculated;
[0073] A302. The size of the corresponding placement area is determined according to the number of reagents in each reagent group;
[0074] A303. The position of each placement area is determined according to the average hazard index of each reagent group, the size of the corresponding placement area, and the position of the preset operation area on the test bench;
[0075] A304. Each placement area is displayed on the test bench according to the position and size of each placement area.
[0076] The position of each placement area is determined according to the average hazard index of each reagent group and the position of the preset operation area, wherein the reagents with higher hazard can be placed at a position farther away from the preset operation area, thereby reducing the harm to the operator.
[0077] In step A301, the sum of the hazard indices of the reagents in the same reagent group is divided by the number of reagents to obtain the average hazard index of the reagent group.
[0078] The placement area can be, but is not limited to, a circular area, an elliptical area, a rectangular area, or other polygonal areas, etc. Preferably, the placement area is a rectangular area, which can more fully utilize the test bench surface space.
[0079] In step A302, the corresponding reference size is obtained in the reference size query table according to the number of reagents in each reagent group, as the size of the corresponding placement area.
[0080] In step A302, the size of the placement region can also be determined according to the preset inter-bottle interval L0 (which can be set according to actual needs) and the number of reagents in the reagent group; for example, the placement region is set as a rectangular region, and the following is performed:
[0081] If the number n of reagents in the reagent group does not exceed the preset first threshold m (which can be set according to actual needs), the length of the corresponding placement region is set as n*L0, and the width is set as L0.
[0082] If the number n of reagents in the reagent group exceeds the preset first threshold m and is an integer multiple of the first threshold m, the length of the corresponding placement region is set as n*L0, and the width is set as k*L0, where k is the multiple of n relative to m.
[0083] If the number n of reagents in the reagent group exceeds the preset first threshold m and is not an integer multiple of the first threshold m, the length of the corresponding placement region is set as n*L0, and the width is set as j*L0, where j is equal to the integer part of the quotient of n divided by m plus 1.
[0084] Thus, it can be ensured that the placement region has sufficient space to place the reagents in the reagent group, so that the reagent bottles of each reagent after placement can have sufficient spacing (at least L0 spacing) between them, thereby reducing the probability of encountering or even overturning other reagent bottles when taking and placing reagents.
[0085] The preset operation region is usually arranged at a position in the middle of the front side (the front side refers to the side close to the operator during the test) of the test bench, so as to facilitate the operator to perform test operation. The operation region is used to place test equipment to perform test operation, but is not limited thereto. In some embodiments, step A303 includes:
[0086] According to the size of the average hazard index, the reagent groups are sorted in descending order;
[0087] According to the sorting order, each reagent group is taken as a target group in turn, and the following is performed:
[0088] A minimum circumscribed rectangular window of the placement region of the target group (if the placement region is a rectangular region, the minimum circumscribed rectangular window is actually the boundary of the placement region) is used to perform window scanning in a preset order (for example, from left to right and from back to front) on the test bench surface to search for a first region that can place the minimum circumscribed rectangular window and does not interfere with the placement regions with determined positions and the operation region.
[0089] From the searched placement positions, a first region farthest from the placement region is selected as a target region, and the placement region of the target group is arranged at the target region (specifically, the center of the placement region of the target group is made to coincide with the center of the target region).
[0090] Thus, the higher the hazard of the reagent group, the farther the placement area from the operation area, and the lower the harm to the operator.
[0091] Preferably, after the reagent groups are sorted in descending order according to the average hazard index, the following step is performed:
[0092] If the difference between the average hazard indexes of two reagent groups sorted adjacently is less than a preset difference threshold (which can be set according to actual needs), the average number of uses of the reagents in each of the two reagent groups is calculated (the average number of uses of the reagents in each reagent group is obtained by dividing the sum of the number of uses of the reagents in the reagent group by the number of reagents), and the sorting of the reagent group with the smaller average number of uses is adjusted to be before the sorting of the reagent group with the larger average number of uses.
[0093] For example, if the difference between the average hazard indexes of the reagent group A sorted at the i-th and the reagent group B sorted at the i+1-th is less than the preset difference threshold, if the average number of uses of the reagents in the reagent group A is not greater than the average number of uses of the reagents in the reagent group B, the sorting of the reagent group A is kept as the i-th and the sorting of the reagent group B is kept as the i+1-th, if the average number of uses of the reagents in the reagent group A is greater than the average number of uses of the reagents in the reagent group B, the sorting of the reagent group A is adjusted to the i+1-th and the sorting of the reagent group B is adjusted to the i-th.
[0094] Thus, under similar hazard levels, the placement area of the reagent group with a larger average number of uses is closer to the operator, so as to facilitate the operator to take and place the reagents that need to be used multiple times, and improve the operation convenience.
[0095] In step A304, the placement areas can be displayed on the test bench by projection, lighting of different positions of the test bench, or other ways. For example, in some embodiments, the step of displaying the placement areas on the test bench comprises:
[0096] The placement areas are displayed by an LED array on the test bench.
[0097] That is, the test bench is provided with an array of LED lights, and the display of the placement areas is realized by lighting the LED lights at corresponding positions, so as to visually guide the operator to place the reagents. In the display, only the LED lights at the edges of the placement areas can be lit, or all the LED lights in the placement areas can be lit, or the LED lights at the edges of the placement areas are lit and the numbers of the placement areas are displayed by the LED lights inside the placement areas. Different colors can be displayed for different placement areas to facilitate the operator to distinguish the placement areas.
[0098] In some preferred embodiments, after step A3 and before step A4, the following step is further included:
[0099] The display displays the grouping results of the reagents and the corresponding relationship information between each reagent group and each placement area (the corresponding relationship information can be the color or code correspondence between each reagent group and each placement area).
[0100] In order to facilitate the operator to place the reagents according to the content displayed by the display.
[0101] Specifically, step A4 comprises:
[0102] A401. Real-time acquisition of video information of the test bench;
[0103] A402. Analyzing the video information based on an image analysis method to obtain the real-time placement position of each reagent;
[0104] A403. If the real-time placement position of at least one reagent is not in the corresponding placement area, it is determined that a first rule violation operation condition indicating that the reagent placement position is incorrect occurs.
[0105] In fact, the corresponding mark can be previously set on the reagent bottle cap of each reagent, and the real-time placement position of the corresponding reagent is obtained by recognizing the mark.
[0106] Further, step A4 further comprises:
[0107] A404. Analyzing the video information based on an image analysis method to obtain the opening time of the reagent bottle of each reagent;
[0108] A405. According to the volatility parameter and the harmfulness parameter of each reagent, the opening upper limit time of the reagent bottle of each reagent is obtained;
[0109] A406. If the opening time of the reagent bottle of at least one reagent exceeds the corresponding opening upper limit time, it is determined that a second rule violation operation condition indicating that the reagent bottle is not timely closed occurs.
[0110] Among them, one reagent in the laboratory (which can be selected according to actual needs) can be determined as a reference reagent in advance, and the volatility parameter and the harmfulness parameter of the reference reagent are taken as the reference volatility parameter and the reference harmfulness parameter, and the opening upper limit time of the reference reagent is set as the reference opening upper limit time in advance. In step A405, the ratio of the volatility parameter of each reagent to the reference volatility parameter is calculated, which is denoted as the first ratio, the ratio of the harmfulness parameter of each reagent to the reference harmfulness parameter is calculated, which is denoted as the second ratio, then the adjustment coefficient is calculated according to the first ratio and the second ratio, and finally the adjustment coefficient is multiplied by the reference opening upper limit time to obtain the opening upper limit time of the reagent bottle of each reagent. When calculating the adjustment coefficient according to the first ratio and the second ratio, the following formula can be used for calculation, but it is not limited thereto:
[0111] ;
[0112] wherein, is an adjustment coefficient, , , are all preset parameters (which can be set according to actual needs), is a first ratio, is a second ratio, is a preset opening time threshold value (which can be set according to actual needs).
[0113] Further, step A5 comprises:
[0114] if the first violation operation condition occurs, a first warning signal requiring correct placement of the reagent is sent out;
[0115] if the second violation operation condition occurs, a second warning signal requiring timely closing of the reagent bottle is sent out.
[0116] For example, the first warning signal and the second warning signal can include at least one of an acoustic signal, a light signal, and a text signal.
[0117] In some embodiments, the pharmaceutical preparation test monitoring method further comprises a step of:
[0118] adjusting the power of the air suction device of the fume hood according to the maximum value of the hazard index of the reagent required to be used in the test.
[0119] Thus, while ensuring that harmful waste gas can be effectively adsorbed, electricity is saved.
[0120] For example, a corresponding reference power can be set for different hazard index ranges in advance to form a power query table; the corresponding reference power is obtained in the power query table according to the maximum value of the hazard index of the reagent required to be used in the test, and then the power of the air suction device of the fume hood is adjusted to the reference power.
[0121] As can be seen from the above, the pharmaceutical preparation test monitoring method, by acquiring test information; the test information includes reagent information of a reagent required to be used in the test; grouping the reagents according to the reagent information to obtain at least one reagent group; displaying a placement area corresponding to each reagent group on the test bench according to the grouping result; monitoring the test operation condition in real time, and judging whether a violation operation condition occurs based on the placement area and the grouping result; the violation operation condition includes a first violation operation condition indicating that the reagent is placed in an incorrect position and a second violation operation condition indicating that the reagent bottle is not timely closed; when the violation operation condition occurs, a warning is sent out; thus, the pharmaceutical preparation test process can be effectively monitored, and it is beneficial to reduce the occurrence of operation violations.
[0122] Please refer to Figure 3 , Figure 3A structural schematic diagram of an electronic device provided by an embodiment of the present application, the present application provides an electronic device, comprising: a processor 301 and a memory 302, the processor 301 and the memory 302 are interconnected and communicate with each other through a communication bus 303 and / or other forms of connection mechanism (not marked), the memory 302 stores a computer program executable by the processor 301, when the electronic device runs, the processor 301 executes the computer program to execute the drug preparation test monitoring method in any optional implementation manner of the above-mentioned embodiments, to realize the following functions: obtaining test information; the test information includes reagent information of reagents required to be used in the test; grouping the reagents according to the reagent information, obtaining at least one reagent group; displaying the placement area corresponding to each reagent group on the test bench according to the grouping result; monitoring the test operation in real time, and judging whether the violation operation condition occurs based on the placement area and the grouping result; the violation operation condition includes a first violation operation condition indicating that the reagent placement position is incorrect and a second violation operation condition indicating that the reagent bottle is not timely closed; when the violation operation condition occurs, a warning is issued.
[0123] The present application provides a computer readable storage medium, which stores a computer program, when the computer program is executed by a processor, the drug preparation test monitoring method in any optional implementation manner of the above-mentioned embodiments is executed, to realize the following functions: obtaining test information; the test information includes reagent information of reagents required to be used in the test; grouping the reagents according to the reagent information, obtaining at least one reagent group; displaying the placement area corresponding to each reagent group on the test bench according to the grouping result; monitoring the test operation in real time, and judging whether the violation operation condition occurs based on the placement area and the grouping result; the violation operation condition includes a first violation operation condition indicating that the reagent placement position is incorrect and a second violation operation condition indicating that the reagent bottle is not timely closed; when the violation operation condition occurs, a warning is issued. Wherein, the computer readable storage medium can be realized by any type of volatile or non-volatile storage device or their combination, such as static random access memory (SRAM), electrically erasable programmable read-only memory (EEPROM), erasable programmable read-only memory (EPROM), programmable read-only memory (PROM), read-only memory (ROM), magnetic memory, flash memory, magnetic disk or optical disk.
[0124] Reference Figure 2 、 Figure 4 The application provides a fume hood, comprising a fume hood body, the fume hood body is provided with a test window 3 and a test table 4 located at the bottom of the test window 3, and further comprising a central controller 6, a camera 7, an LED array 8 and an alarm device 9, the camera 7 is arranged at the top of the test window 3, the LED array 8 is arranged at the top of the test table 4, and the fume hood body, the camera 7, the LED array 8 and the alarm device 9 are electrically connected with the central controller 6.
[0125] The central controller 6 is used for:
[0126] acquiring test information, wherein the test information comprises reagent information of reagents required for the test (for a specific process, refer to step A1 in the foregoing description);
[0127] grouping the reagents according to the reagent information to obtain at least one reagent group (for a specific process, refer to step A2 in the foregoing description);
[0128] controlling the LED array 8 to display a placement area corresponding to each reagent group on the test table 4 according to the grouping result (for a specific process, refer to step A3 in the foregoing description);
[0129] monitoring a test operation condition in real time through the camera 7 and judging whether a violation operation condition occurs based on the placement area and the grouping result, wherein the violation operation condition comprises a first violation operation condition indicating that a reagent is placed at an incorrect position and a second violation operation condition indicating that a reagent bottle is not timely closed (for a specific process, refer to step A4 in the foregoing description);
[0130] when the violation operation condition occurs, issuing a warning through the alarm device 9 (for a specific process, refer to step A5 in the foregoing description).
[0131] Specifically, the fume hood body comprises a cabinet 1, a suction device 11 arranged in the cabinet 1 and an exhaust port 2, the cabinet 1 is provided with the test window 3, the bottom of the test window 3 is provided with the test table 4, the side wall and / or the top of the test window 3 is provided with an air suction port 5, and the suction device 11 sucks air through the air suction port 5 and discharges the air through the exhaust port 2.
[0132] In some preferred embodiments, the fume hood further comprises a display 10, and the central controller 6 is further used for displaying the grouping result of the reagents and correspondence information between each reagent group and each placement area through the display 10 (the correspondence information can be a color or code correspondence between each reagent group and each placement area).
[0133] so as to place the reagents according to the content displayed on the display 10 by an operator.
[0134] In some preferred embodiments, the central controller 6 is further configured to adjust the power of the air suction device 11 of the fume hood according to the maximum value of the hazard index of the reagent required by the experiment.
[0135] Thus, the harmful waste gas can be effectively adsorbed while saving electricity.
[0136] For example, the corresponding reference power can be set in advance for different hazard index ranges to form a power query table; the corresponding reference power is obtained in the power query table according to the maximum value of the hazard index of the reagent required by the experiment, and then the power of the air suction device 11 of the fume hood is adjusted to the reference power.
[0137] In the embodiments provided in the present application, it should be understood that the disclosed devices and methods can be implemented in other ways. The device embodiments described above are only illustrative, for example, the division of the units is only a logical function division, and actual implementation can have another division manner, and for example, a plurality of units or components can be combined or integrated into another system, or some features can be ignored or not executed. In addition, the coupling or direct coupling or communication connection between the units shown or discussed can be indirect coupling or communication connection through some communication interfaces, devices or units, which can be electrical, mechanical or other forms.
[0138] In addition, the units described as separate components can or can not be physically separate, and the components shown as units can or can not be physical units, which can be located in one place or distributed on multiple network units. Some or all units can be selected according to actual needs to achieve the purpose of the embodiments.
[0139] Furthermore, the functional modules in each embodiment of the present application can be integrated together to form an independent part, or each module can exist independently, or two or more modules can be integrated to form an independent part.
[0140] In this paper, the relationship terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between the entities or operations.
[0141] The above description is only for the embodiments of the present application and is not used to limit the protection scope of the present application. For those skilled in the art, the present application can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims
1. A method for monitoring drug preparation experiments, applied in a fume hood, characterized in that, The method comprises the steps of: A1. obtaining test information; the test information comprises reagent information of reagents required for a test; A2. grouping the reagents according to the reagent information, to obtain at least one reagent group; A3. displaying a placement area corresponding to each reagent group on a test bench according to the grouping result; A4. monitoring the test operation in real time, and judging whether a violation operation condition occurs based on the placement area and the grouping result; the violation operation condition comprises a first violation operation condition indicating incorrect placement of reagents and a second violation operation condition indicating that a reagent bottle is not timely closed; A5. issuing a warning when the violation operation condition occurs; The reagent information comprises reagent identification information, volatility parameters and harmfulness parameters; Step A2 comprises: calculating a hazard index of each reagent according to the volatility parameters and the harmfulness parameters of the reagent; grouping the reagents according to the hazard index; Step A4 comprises: collecting video information of the test bench in real time; analyzing the video information based on an image analysis method to obtain a real-time placement position of each reagent; if the real-time placement position of at least one reagent is not in the corresponding placement area, it is determined that the first violation operation condition indicating incorrect placement of reagents occurs; Step A4 further comprises: analyzing the video information based on an image analysis method to obtain an opening time of a reagent bottle of each reagent; obtaining an upper limit time of opening of a reagent bottle of each reagent according to the volatility parameters and the harmfulness parameters of the reagent; if the opening time of the reagent bottle of at least one reagent exceeds the corresponding upper limit time of opening, it is determined that the second violation operation condition indicating that the reagent bottle is not timely closed occurs.
2. The pharmaceutical preparation test monitoring method according to claim 1, characterized by, Step A3 comprises: calculating an average hazard index of each reagent group according to the hazard index of each reagent; determining the size of the corresponding placement area according to the number of reagents in each reagent group; determining the position of each placement area according to the average hazard index of each reagent group, the size of the corresponding placement area, and the position of a preset operation area on the test bench; displaying each placement area on the test bench according to the position and size of each placement area.
3. The pharmaceutical preparation test monitoring method according to claim 2, characterized by, The step of displaying each placement area on the test bench comprises: displaying each placement area through an LED array on the test bench.
4. An electronic device, comprising: The device comprises a processor and a memory, the memory stores a computer program executable by the processor, and the processor executes the computer program to run the steps of the pharmaceutical preparation test monitoring method according to any one of claims 1-3.
5. A computer-readable storage medium having stored thereon a computer program, characterized in that, The computer program is executed by the processor to run the steps of the pharmaceutical preparation test monitoring method according to any one of claims 1-3.
6. A fume hood for use in the pharmaceutical preparation test monitoring method according to any one of claims 1 to 3, comprising a fume hood main body provided with a test window and a test table located at the bottom of the test window, characterized in that, The device further comprises a central controller, a camera, an LED array and an alarm device, the camera is arranged at the top of the test window, the LED array is arranged at the top of the test bench, and the fume hood body, the camera, the LED array, the alarm device are all electrically connected with the central controller; The central controller is used for: acquiring test information; the test information includes reagent information of reagents required for a test; grouping the reagents according to the reagent information to obtain at least one reagent group; controlling the LED array to display a placement area corresponding to each reagent group on a test bench according to the grouping result; monitoring test operation in real time through the camera and judging whether a violation occurs based on the placement area and the grouping result; the violation includes a first violation indicating incorrect reagent placement and a second violation indicating that a reagent bottle is not closed in time; issuing a warning through the alarm device when a violation occurs; the reagent information includes reagent identification information, volatility parameters, and harmfulness parameters; grouping the reagents according to the reagent information to obtain at least one reagent group, specifically including: calculating a hazard index of each reagent according to the volatility parameters and the harmfulness parameters of the reagent; grouping the reagents according to the hazard index; monitoring test operation in real time through the camera and judging whether a violation occurs based on the placement area and the grouping result, specifically including: collecting video information of the test bench in real time; analyzing the video information based on an image analysis method to obtain real-time placement positions of the reagents; if the real-time placement position of at least one reagent is not in the corresponding placement area, determining that the first violation indicating incorrect reagent placement occurs; analyzing the video information based on an image analysis method to obtain opening times of reagent bottles of the reagents; obtaining opening upper limit times of the reagent bottles of the reagents according to the volatility parameters and the harmfulness parameters of the reagents; if the opening time of the reagent bottle of at least one reagent exceeds the corresponding opening upper limit time, determining that the second violation indicating that the reagent bottle is not closed in time occurs.
Citation Information
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