A high-pressure resistant sterile quick connector

Abstract

This invention relates to the field of biopharmaceutical technology, specifically disclosing a high-pressure resistant sterile quick connector, including a female connector and a male connector of similar specifications. Both the top center of the female connector and the bottom center of the male connector are provided with a flexible connector with a reverse buckle, allowing connection to pipes of different sizes. Both the female and male connectors have flow channels communicating with the flexible connector at their center. A sterile connection device is provided at the top center of the male connector and the bottom center of the female connector. A protective jacket with an L-shaped cross-section is fixed to the outer circumference of the female connector. In this invention, the snap-fit ​​assembly of the male and female connectors is adjustable and remains fixed after adjustment, improving the locking stability of the male and female connectors, ensuring a complete seal of the internal channel, preventing the introduction of bacteria, and employing a multi-layered membrane sealing method to ensure sterility, providing multiple safeguards for the sterile environment within the channel.

Description

Technical Field

[0001] This invention relates to the field of biopharmaceutical technology, and more specifically, to a high-pressure resistant sterile quick connector. Background Technology

[0002] In biopharmaceutical processes, it is generally relatively easy to sterilize and maintain the sterility of materials within a closed process. However, in some cases, it is necessary to disconnect the closed process and reconnect it to a new process while ensuring that the materials are not contaminated. Although the clean environments of pharmaceutical companies can provide a certain level of cleanliness, this level of cleanliness is insufficient to provide sterile protection after material exposure. To meet the requirements of production processes and product quality, sterile connectors are a solution for sterile control during this exposure and reconnection process.

[0003] Existing aseptic connectors typically form a sterile channel by bonding two silicone pads together. The seal is mainly achieved through the closing deformation of the silicone pads, and the bonding joint is only tightened by external force, which cannot withstand excessive pressure. In biopharmaceutical processes, drug transfer sometimes requires the use of peristaltic pumps to accelerate the transfer efficiency. Infusion channels may also incorporate sterile filters to filter the drug solution. After filtration, the filter undergoes an integrity test. In these situations, high pressure is generated within the infusion channel, posing a risk of leakage to ordinary aseptic connectors. Furthermore, in ordinary aseptic connectors, the drug solution channel is formed by two silicone pads bonded together, with the drug solution in direct contact with the silicone pads. During the peeling process of the antibacterial and breathable membrane, there is still a small probability of introducing external bacteria onto the silicone pads, making it impossible to completely eliminate the risk of drug contamination.

[0004] A search revealed a sterile connector with a folded sealing membrane structure, disclosed in patent publication number CN116085551A. This connector includes a body, a clamp, a sealing ring, a sealing membrane, and a protective cover. The body and clamp are provided with a passageway for easily pulling out the sealing membrane. In some embodiments of this invention, the sealing membrane is further removed after mating, preventing the fluid passage from being exposed to the external environment before connection and ensuring the sterility of the fluid passage. Furthermore, the connectors are not gender-specific; the two mating sterile connectors have identical structures, significantly reducing manufacturing costs and facilitating use. In the process of implementing this solution, the following problems were found in the existing technology that have not been well resolved: (1) When the sterile quick connector in the existing technology is used to reinforce the male and female connectors, there is only one reinforcement method. After the snap-fit ​​is fixed, the internal structure cannot maintain sufficient stability and there are still gaps and looseness; (2) When the membrane sealing method is used for antibacterial purposes, only one sealing membrane is used, and the sealing effect is limited and cannot guarantee a fully sealed environment; (3) After the entire connector is connected, the fluid channel inside the connector does not have a sufficient sealing effect. The internal structure of the fluid channel is relatively simple and cannot provide sufficient sealing performance. Therefore, a high-pressure resistant sterile quick connector is urgently needed to solve the above problems. Summary of the Invention

[0005] To address the problems in related technologies, this invention proposes a high-pressure resistant sterile quick connector. This overcomes the limitations of existing technologies where only one set of male and female connectors is used for reinforcement, resulting in insufficient internal stability. Furthermore, when using membrane sealing for antibacterial purposes, only one type of sealing membrane is employed, leading to limited sealing effectiveness and an inability to guarantee a fully sealed environment. Additionally, the fluid channels within the connector lack sufficient sealing, and their simple internal structure fails to provide adequate sealing performance or improve high-pressure resistance. These issues result in the risk of leakage in ordinary sterile connectors and the inability to completely prevent contamination of medications.

[0006] The technical solution of this invention is implemented as follows:

[0007] A high-pressure resistant sterile quick connector includes a female connector and a male connector of similar specifications. Both the top center of the female connector and the bottom center of the male connector are provided with a flexible connector with a reverse loop, allowing connection to pipes of different sizes. Both the female and male connectors have flow channels at their center, communicating with the flexible connector. A sterile connection device is provided at the top center of the male connector and the bottom center of the female connector. The sterile connection device includes an annular groove at the top center of the male connector and the bottom center of the female connector, and a sealing component. A protective jacket is fixed to the outer circumference of the female connector, and the protective jacket has an L-shaped cross-section, with a thickness greater than that of the female connector. A connection is fixed to the outer circumference of the male connector. The protective inner sleeve has the same thickness as the head, and the outer circumference of the inner sleeve matches the bottom of the inner circumference of the outer sleeve. A series of infinitely close-fitting components are arranged in a ring at equal intervals between the bottom of the outer sleeve and the top of the inner sleeve, ensuring a completely sealed connection of the internal channel and improving the pressure resistance of the aseptic connector. This provides multiple guarantees for the sterility of the channel. The female connector, male connector, outer sleeve, and inner sleeve are all constructed of corrosion-resistant stainless steel. The male and female connectors of the entire aseptic quick connector adopt a similar structural design, resulting in a simple, reliable, and easy-to-manufacture structure with low cost, significantly reducing manufacturing costs and facilitating use. This avoids the manufacturing and usage inconveniences caused by male-female designs and enhances the overall strength of the quick connector, giving it high pressure resistance.

[0008] Furthermore, the sealing assembly includes an outer cone fixed at the middle position of the inner wall of the annular groove on the male connector and an inner cone fixed at the middle position of the inner wall of the annular groove on the female connector. The inner wall of the annular groove on the male connector is provided with a first annular sealing gasket sleeved on the outside of the outer cone. A barrier membrane is provided between the top of the first annular sealing gasket and the top of the outer cone and the bottom of the inner cone.

[0009] Furthermore, the sealing assembly includes an outer cone fixed at the middle position of the inner wall of the annular groove on the male connector and an inner cone fixed at the middle position of the inner wall of the annular groove on the female connector. The inner walls of the two annular grooves are respectively provided with a first annular sealing gasket sleeved on the outside of the inner cone and the outside of the outer cone. A barrier membrane is provided between the top of the first annular sealing gasket and the top of the outer cone and the bottom of the inner cone.

[0010] Furthermore, the sealing assembly includes an outer cone fixed at the middle position of the inner wall of the annular groove on the male connector and an inner cone fixed at the middle position of the inner wall of the annular groove on the female connector. The inner wall of the annular groove on the male connector is provided with a first annular sealing gasket sleeved on the outside of the outer cone. A barrier membrane is provided between the top of the first annular sealing gasket and the top of the outer cone and the bottom of the inner cone. The inner walls of the two annular grooves are respectively provided with second annular sealing gaskets located inside the inner cone and outside the outer cone. The second annular sealing gaskets are designed with a thin-walled structure.

[0011] Furthermore, the first annular sealing gasket is interference-fitted with the annular groove, and the first annular sealing gasket is a hollow structure filled with gas. The first annular sealing gasket is designed in a corrugated shape to avoid asynchronous movement that could introduce bacteria, completely avoiding the risk of contamination of the medication. This ensures that when assembling the female and male connectors, on the one hand, the first annular sealing gasket will be fully fitted into the annular groove under compression, ensuring the sealing performance of the annular groove. On the other hand, the first annular sealing gasket will be compressed and expanded laterally. At this time, under the action of expansion force, the inner cone and the outer cone are fully tightened, further ensuring the sealing performance of the entire sterile quick connector.

[0012] Furthermore, the barrier membrane is a PTFE membrane with a pore size of 0.2μm, and the barrier membrane is folded into a double layer. One layer of the barrier membrane is welded to the end face of the aseptic connection device using a false welding process, and completely covers the first annular sealing gasket, inner cone, and outer cone. A breathable membrane with adhesive backing is pasted on the folded, unwelded layer of the barrier membrane, and the breathable membrane is folded and overlaps with the barrier membrane. The folded part of the breathable membrane extends to the other side of the aseptic connection device. Both sides of the top of the female connector and both sides of the top of the male connector have through-membrane slots, and one end of the barrier membrane and one end of the breathable membrane pass through the interior of the membrane slots. The ends of the membrane slots are all designed as bevels, and the ends of the membrane slots are all clamped with limit seats. The barrier membrane and the breathable membrane are pressed into the interior of the membrane slots by the limit seats. The sealing performance is fully maintained through the cooperation of the multiple layers of barrier membrane and breathable membrane.

[0013] Furthermore, the inner cone and the outer cone are respectively provided with liquid channels communicating with the flow channel hole at their center positions. The liquid channels are also connected to the connector hose. The outer wall of the outer cone is provided with multiple annular protrusions of different specifications, and the inner wall of the inner cone is provided with multiple grooves that are adapted to the specifications of the protrusions. The inner circumference of the first annular sealing gasket is adapted to the outer circumference of the inner cone. The dimensions of the outer cone and the inner cone are proportionally enlarged with reference to the inner and outer cone dimensions in GB / T 1962.1. Through the action of the protrusions and grooves, the contact surface of the inner cone and the outer cone is irregular, which ensures the sealing performance and also prevents the two from easily separating.

[0014] Furthermore, both sides of the top of the female connector and both sides of the top of the male connector are provided with through-membrane slots, and one end of the barrier membrane and one end of the breathable membrane pass through the interior of the membrane slots respectively. The ends of the membrane slots are all designed as bevels, and the ends of the membrane slots are all clamped with limit seats. The barrier membrane and the breathable membrane are pressed into the interior of the membrane slots by the limit seats. The limit seats fix the barrier membrane and the breathable membrane in the membrane slots to prevent the barrier membrane and the breathable membrane from detaching from the membrane slots.

[0015] Furthermore, the stepless snap-fit ​​assembly includes mounting grooves evenly spaced on the bottom of the outer circumference of the protective sleeve, with guide openings at the bottom of each mounting groove. Two guide holes are located above and below the guide openings at the bottom of each mounting groove. Guide rods are inserted into the two guide holes, and a common locking tooth block is fixed to one end of each guide rod. A pressing component is provided on one side of the locking tooth block and inside the mounting groove. The top of the protective inner sleeve has evenly spaced mating slots, the number of which matches the number of mounting grooves. A guide groove is provided between one inner wall of the mating slot and the outer wall of the protective inner sleeve, and an evenly spaced locking tooth groove is provided on the other inner wall of the mating slot. The locking tooth block is inserted into the mating slot and engages with it. The locking action of multiple sets of stepless snap-fit ​​assemblies reinforces the male and female connectors, allowing the entire snap-fit ​​assembly to be adjusted arbitrarily and then fixed, thus improving the locking stability of the male and female connectors.

[0016] Furthermore, the pressing assembly includes a pressing plate rotatably connected to the inner wall of the mounting groove, and a spring is fixed between the top of one side of the pressing plate and the top of one side of the mounting groove. A connecting groove is provided at the bottom of the pressing plate, and a traction plate passing through the connecting groove is rotatably connected to one side of the locking tooth block. The position of the traction plate corresponds to the position of the guide groove. Movable grooves are provided between both ends of the connecting groove and the outer walls of both ends of the pressing plate, and a pin inserted into the movable groove is rotatably connected to one end of the traction plate. By pressing the pressing plate, the traction plate is moved, causing the locking tooth block to disengage from the locking tooth groove to achieve the locking operation of the female connector and the male connector, which facilitates assembly.

[0017] Furthermore, the top of the protective inner sleeve is provided with positioning holes that are evenly spaced in a ring, and the bottom corner of the protective outer sleeve is fixed with positioning rods that are evenly spaced and adapted to the inner wall of the positioning holes. The positions of the positioning holes and the positions of the mating slots are staggered. During the mating process of the female connector and the male connector, the user maintains the mating stability of the two through the positioning rods and positioning holes, and also ensures the mating performance of the stepless snap fastener assembly.

[0018] The beneficial effects of this invention are:

[0019] Firstly, the present invention provides a high-pressure resistant sterile quick connector. Through the cooperation of a female connector, male connector, protective outer sleeve, protective inner sleeve, positioning rod, positioning hole, and stepless snap fastener assembly, the positioning rod and positioning hole maintain the stability of the connection between the female and male connectors during the docking process. The locking action of multiple sets of stepless snap fastener assembly reinforces the connection between the male and female connectors, allowing the entire snap fastener assembly to be arbitrarily adjustable and fixed after adjustment. This improves the locking firmness of the male and female connectors, replacing the existing technology that uses only one set of snap fastener structure for fixing. This ensures sufficient stability after the snap fastener is fixed, avoiding problems such as gaps and loosening.

[0020] Secondly, the present invention provides a high-pressure resistant sterile quick connector. Through the cooperation of the female connector, male connector and sterile connection device, when the male connector and female connector are engaged, the folded breathable membrane with adhesive backing is pulled until it is completely separated from the connector, so that the sterile adhesive backing layer on the folded barrier membrane of the male and female connector is exposed and bonded. Then, the folded barrier membrane in the membrane slot on one side of the sterile connection device is taken out, and the folded barrier membrane is pulled until the sparse weld layer is completely separated from the sterile connection device, so that the first annular sealing gasket is completely locked with the annular groove, and the outer cone is embedded in the inner cone to form a fully sealed environment, ensuring that the internal channel achieves a completely sealed connection. This can avoid the introduction of bacteria due to asynchronous movement and completely avoid the risk of drug contamination. The multi-layer membrane sealing method greatly ensures the sterility of the sterile channel and provides multiple guarantees for the sterility of the channel.

[0021] Thirdly, the high-pressure resistant sterile quick connector provided by this invention, through the cooperation of the first annular sealing gasket, the inner cone and the outer cone, because the first annular sealing gasket is designed as a hollow corrugated structure filled with gas, when assembling the female connector and the male connector, on the one hand, the first annular sealing gasket will fully fit into the annular groove under the compression action, ensuring the sealing performance of the annular groove; on the other hand, the first annular sealing gasket will be compressed and expanded laterally, at this time, under the action of the expansion force, the inner cone and the outer cone are fully tightened, ensuring that the fluid channel inside the connector has a sufficient sealing effect;

[0022] Fourthly, the present invention provides a high-pressure resistant sterile quick connector. Through the cooperation of the female connector, male connector, protective outer sleeve, protective inner sleeve, connector hose, etc., the female connector, male connector, protective outer sleeve and protective inner sleeve are constructed of corrosion-resistant stainless steel. This makes the male and female connectors of the entire sterile quick connector adopt a similar structural design, which is simple and reliable, easy to manufacture, and low in cost, greatly reducing manufacturing costs and facilitating use. It avoids the inconvenience of manufacturing and use caused by male and female designs, and provides the strength of the entire quick connector, giving it high pressure resistance. Attached Figure Description

[0023] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0024] Figure 1 This is a front sectional view of a high-pressure resistant sterile quick connector.

[0025] Figure 2 This is a three-dimensional structural diagram of a high-pressure resistant sterile quick connector.

[0026] Figure 3 This is a front view schematic diagram of a high-pressure resistant sterile quick connector.

[0027] Figure 4 This is a diagram showing the completed assembly of a high-pressure resistant sterile quick connector.

[0028] Figure 5 This is a cross-sectional view of a female connector of a high-pressure resistant sterile quick connector.

[0029] Figure 6 This is a schematic diagram of the male connector and the first annular sealing gasket structure of a high-pressure resistant sterile quick connector.

[0030] Figure 7 This is a schematic diagram of the outer cone structure of a high-pressure resistant sterile quick connector.

[0031] Figure 8 This is a schematic diagram of the protective jacket and mounting groove structure of a high-pressure resistant sterile quick connector.

[0032] Figure 9 Cross-sectional view of the protective jacket of a high-pressure resistant sterile quick connector.

[0033] Figure 10 This is a schematic diagram of the stepless snap-fit ​​assembly structure of a high-pressure resistant sterile quick connector.

[0034] Figure 11 This is a schematic diagram of the structure of Example 2.

[0035] Figure 12 This is a schematic diagram of the structure of Example 3.

[0036] In the picture:

[0037] 1. Female connector; 2. Male connector; 3. Connector hose; 4. Protective outer sleeve; 5. Limiting seat; 6. Stepless buckle assembly; 601. Clamping tooth block; 602. Pressing plate; 603. Spring; 604. Guide rod; 605. Connecting groove; 606. Movable groove; 607. Traction plate; 7. Docking groove; 8. Guide groove; 9. Protective inner sleeve; 10. Breathable membrane; 11. Barrier membrane; 12. Annular groove; 13. Membrane groove; 14. Inner cone; 15. Outer cone; 16. First annular sealing gasket; 17. Clamping tooth groove; 18. Positioning rod; 19. Positioning hole; 20. Protruding edge; 21. Mounting groove; 22. Guide opening; 23. Guide hole; 24. Second annular sealing gasket. Detailed Implementation

[0038] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention are within the scope of protection of the present invention.

[0039] Please see Figures 1-12A high-pressure resistant sterile quick connector includes a female connector 1 and a male connector 2 of similar specifications. Both the top center of the female connector 1 and the bottom center of the male connector 2 are provided with a flexible connector 3 with an undercut, allowing connection to pipes of different sizes. Both the center of the female connector 1 and the center of the male connector 2 have flow channels communicating with the flexible connector 3. A sterile connection device is provided at the top center of the male connector 2 and the bottom center of the female connector 1. The sterile connection device includes an annular groove 12 formed at the top center of the male connector 2 and the bottom center of the female connector 1, and a sealing component. A protective sleeve 4 is fixed to the outer circumference of the female connector 1, and the cross-section of the protective sleeve 4 is L-shaped. The thickness of the protective outer sleeve 4 is greater than the thickness of the female connector 1. A protective inner sleeve 9 with the same thickness as the male connector 2 is fixed to the outer circumferential wall of the male connector 2, and the outer circumferential wall of the protective inner sleeve 9 matches the bottom of the inner circumferential wall of the protective outer sleeve 4. A continuously variable snap-fit ​​assembly 6 is provided between the bottom of the protective outer sleeve 4 and the top of the protective inner sleeve 9 at equal intervals in a ring. The continuously variable snap-fit ​​assembly 6 includes mounting grooves 21 that are equally spaced at the bottom of the outer circumferential wall of the protective outer sleeve 4, and each mounting groove 21 has a guide opening 22 at the bottom. The bottom of the mounting groove 21 has two guide holes 23 distributed above and below the guide openings 22. A guide rod 604 is inserted into each of the two guide holes 23, and one end of each guide rod 604 is fixed with the same locking tooth block. 601, a pressing component is provided on one side of the locking block 601 and inside the mounting groove 21. The top of the protective inner sleeve 9 has evenly distributed mating slots 7, the number of which matches the number of mounting grooves 21. A guide groove 8 is provided between one inner wall of the mating slot 7 and the outer wall of the protective inner sleeve 9. The other inner wall of the mating slot 7 has evenly distributed locking tooth grooves 17. The locking block 601 is inserted into the mating slot 7 and engages with the locking tooth grooves 17. The pressing component includes a pressing plate 602 rotatably connected to the inner wall of the mounting groove 21. A spring 603 is fixed between the top of one side of the pressing plate 602 and the top of one side of the mounting groove 21. A connecting groove 605 is provided at the bottom of the pressing plate 602. The locking block 601... One side of 1 is rotatably connected to a traction plate 607 that passes through a connecting groove 605. The position of the traction plate 607 corresponds to the position of the guide groove 8. Both ends of the connecting groove 605 are provided with movable grooves 606 between the outer walls of the two ends of the pressing plate 602. One end of the traction plate 607 is rotatably connected to a pin inserted into the movable groove 606. The male connector 2 and the female connector 1 are reinforced by the clamping action of multiple sets of stepless buckle assemblies 6. This allows the entire buckle assembly to be adjusted arbitrarily and to have a fixed performance after adjustment, improving the locking firmness of the male connector 2 and the female connector 1. This replaces the fixing method of using only one set of buckle structure in the prior art, so that sufficient stability can be maintained after buckling and fixing, avoiding problems such as gaps and loosening.

[0040] Please see Figure 1 and Figure 2 The top of the inner protective sleeve 9 is provided with positioning holes 19 that are evenly distributed in a ring, and the bottom corner of the outer protective sleeve 4 is fixed with positioning rods 18 that are evenly distributed and adapted to the inner wall of the positioning holes 19. The positions of the positioning holes 19 and the docking slots 7 are staggered. During the docking process of the female connector 1 and the male connector 2, the user maintains the docking stability of the two through the positioning rods 18 and the positioning holes 19, and also ensures the docking fit performance of the stepless buckle assembly 6.

[0041] Example 1:

[0042] Please see Figures 1-10 The sealing assembly includes an outer cone 15 fixed at the middle position of the inner wall of the annular groove 12 on the male connector 2 and an inner cone 14 fixed at the middle position of the inner wall of the annular groove 12 on the female connector 1. A first annular sealing gasket 16 is provided on the inner wall of the annular groove 12 on the male connector 2, which is sleeved on the outside of the outer cone 15. A barrier membrane 11 is provided between the top of the first annular sealing gasket 16 and the top of the outer cone 15 and the bottom of the inner cone 14. The first annular sealing gasket 16 is interference-fitted with the annular groove 12, and the first annular sealing gasket 16 is a hollow structure. The interior of the first annular sealing gasket 16 is filled with gas. The first annular sealing gasket 16 is designed as a corrugated tube.

[0043] The barrier membrane 11 is made of PTFE membrane with a pore size of 0.2μm, and the barrier membrane 11 is folded into a double layer. One layer of the barrier membrane 11 is welded to the end face of the aseptic connection device using a false welding process, and completely covers the first annular sealing gasket 16, the inner cone 14 and the outer cone 15. A breathable membrane 10 with adhesive backing is pasted on the folded, unwelded layer of the barrier membrane 11, and the breathable membrane 10 is folded and overlaps with the barrier membrane 11. The folded part of the breathable membrane 10 extends to the other side of the aseptic connection device. Both sides of the top of the female connector 1 and the top of the male connector 2 are provided with through membrane slots 13, and one end of the barrier membrane 11 and one end of the breathable membrane 10 pass through the interior of the membrane slots 13 respectively. The ends of the membrane slots 13 are all designed as bevels, and the ends of the membrane slots 13 are clamped with limit seats 5. The barrier membrane 11 and the breathable membrane 10 are pressed into the interior of the membrane slots 13 by the limit seats 5.

[0044] The inner cone 14 and the outer cone 15 are respectively provided with liquid channels communicating with the flow channel hole. The liquid channels are also connected to the connector hose 3. The outer wall of the outer cone 15 is provided with multiple annular protrusions 20 of different specifications. The inner wall of the inner cone 14 is provided with multiple slots that are adapted to the specifications of the protrusions 20. The inner circumference of the first annular sealing gasket 16 is adapted to the outer circumference of the inner cone 14.

[0045] During operation, when assembling the female connector 1 and male connector 2, the first annular sealing gasket 16 will fully adhere to the annular groove 12 under compression, ensuring the sealing performance of the annular groove 12. Furthermore, the first annular sealing gasket 16 will expand laterally under compression, and the inner cone 14 and outer cone 15 will be firmly secured under the expansion force, further ensuring the sealing performance of the entire sterile quick connector. When the male connector 2 mates with the female connector 1, pull the folded breathable membrane 10 with adhesive backing until it is completely separated from the connector, exposing and bonding the sterile adhesive layer on the folded barrier membrane 11 of the male and female connectors. Then, remove the folded barrier membrane 11 from the membrane slot 13 on one side of the sterile connection device, and simultaneously pull the folded barrier membrane 11 until the sparse weld layer is completely separated from the sterile connection device, thus ensuring the sealing performance of the first annular sealing gasket 16. The rubber gasket 16 is fully engaged with the annular groove 12, allowing the outer cone 15 to embed into the inner cone 14, forming a fully sealed environment. This ensures a completely sealed connection within the internal channel, preventing the introduction of bacteria due to asynchronous movement and completely eliminating the risk of drug contamination. This provides multiple safeguards for the aseptic properties of the channel. The female connector 1, male connector 2, protective outer sleeve 4, and protective inner sleeve 9 are constructed of corrosion-resistant stainless steel. The male connector 2 and female connector 1 of the entire aseptic quick connector share a similar structural design, resulting in a simple, reliable, and easy-to-manufacture quick connector with low cost. This significantly reduces manufacturing costs and facilitates use, avoiding the manufacturing and usage inconveniences associated with male-female designs. It also enhances the overall strength of the quick connector, giving it high pressure resistance. The dimensions of the outer cone 15 and inner cone 14 conform to GB / T standards. In 1962.1, the inner and outer cone dimensions are enlarged proportionally. The action of the convex edge 20 and the groove makes the contact surface of the inner cone 14 and the outer cone 15 irregular. This ensures the sealing performance and prevents the two from easily separating. The barrier membrane 11 and the breathable membrane 10 in the membrane slot 13 are fixed by the limiting seat 5 to prevent the barrier membrane 11 and the breathable membrane 10 from separating from the membrane slot 13.

[0046] Example 2:

[0047] Please see Figure 11 The sealing assembly includes an outer cone 15 fixed at the middle position of the inner wall of the annular groove 12 on the male connector 2 and an inner cone 14 fixed at the middle position of the inner wall of the annular groove 12 on the female connector 1. The inner walls of the two annular grooves 12 are respectively provided with a first annular sealing gasket 16 sleeved on the outside of the inner cone 14 and the outside of the outer cone 15. A barrier membrane 11 is provided between the top of the first annular sealing gasket 16 and the top of the outer cone 15 and the bottom of the inner cone 14. The first annular sealing gasket 16 is interference-fitted with the annular groove 12, and the first annular sealing gasket 16 is a hollow structure. The inside of the first annular sealing gasket 16 is filled with gas. The first annular sealing gasket 16 is designed as a corrugated tube.

[0048] Example 3:

[0049] Please see Figure 12 The sealing assembly includes an outer cone 15 fixed at the middle position of the inner wall of the annular groove 12 on the male connector 2 and an inner cone 14 fixed at the middle position of the inner wall of the annular groove 12 on the female connector 1. A first annular sealing gasket 16 is provided on the inner wall of the annular groove 12 on the male connector 2, which is sleeved on the outside of the outer cone 15. A barrier membrane 11 is provided between the top of the first annular sealing gasket 16 and the top of the outer cone 15 and the bottom of the inner cone 14. The first annular sealing gasket 16 is interference-fitted with the annular groove 12 and is a hollow structure. The interior of the first annular sealing gasket 16 is filled with gas and is designed as a corrugated tube. The inner walls of the two annular grooves 12 are respectively provided with second annular sealing gaskets 24 located inside the inner cone 14 and outside the outer cone 15. The second annular sealing gaskets 24 are designed as thin-walled structures.

[0050] Finally, the following points should be noted: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installation", "connection", and "fixation" should be interpreted broadly, and can refer to mechanical or electrical connection, or internal connection between two components, or direct connection. "Up", "down", "left", "right", etc. are only used to indicate relative positional relationship. When the absolute position of the described object changes, the relative positional relationship may change.

[0051] Secondly: The accompanying drawings of the embodiments disclosed in this invention only involve the structures involved in the embodiments disclosed in this invention. Other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of this invention can be combined with each other.

[0052] In conclusion, the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

[0053] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A high-pressure resistant sterile quick connector, comprising a female connector (1) and a male connector (2) of similar specifications to the female connector (1), characterized in that, The female connector (1) and the male connector (2) are both provided with a flexible connector (3) with a buckle at the top center and at the bottom center, respectively, which can be connected to pipes of different sizes. The center of the female connector (1) and the center of the male connector (2) are both provided with a flow channel hole communicating with the flexible connector (3). The male connector (2) and the female connector (1) are provided with a sterile connection device at the top center and the bottom center of the female connector (1). The sterile connection device includes an annular groove at the top center of the male connector (2) and the bottom center of the female connector (1). 12) and sealing components, the outer circumferential wall of the female connector (1) is fixed with a protective outer sleeve (4), and the cross-section of the protective outer sleeve (4) is L-shaped. The thickness of the protective outer sleeve (4) is greater than the thickness of the female connector (1). The outer circumferential wall of the male connector (2) is fixed with a protective inner sleeve (9) of the same thickness as the male connector (2). The outer circumferential wall of the protective inner sleeve (9) is matched with the bottom of the inner circumferential wall of the protective outer sleeve (4). There are infinitely fastening components (6) that are evenly distributed in a ring between the bottom of the protective outer sleeve (4) and the top of the protective inner sleeve (9). The sealing assembly includes an outer cone (15) fixed at the middle position of the inner wall of the annular groove (12) on the male connector (2) and an inner cone (14) fixed at the middle position of the inner wall of the annular groove (12) on the female connector (1). The inner wall of the annular groove (12) on the male connector (2) is provided with a first annular sealing gasket (16) sleeved on the outside of the outer cone (15). A barrier membrane (11) is provided between the top of the first annular sealing gasket (16) and the top of the outer cone (15) and the bottom of the inner cone (14). The inner walls of the two annular grooves (12) are respectively provided with a second annular sealing gasket (24) located inside the inner cone (14) and outside the outer cone (15). The second annular sealing gasket (24) is designed as a thin-walled structure.

2. The high-pressure resistant sterile quick connector according to claim 1, characterized in that, The first annular sealing gasket (16) is press-fitted with the annular groove (12), and the first annular sealing gasket (16) is a hollow structure. The interior of the first annular sealing gasket (16) is filled with gas, and the first annular sealing gasket (16) is designed as a corrugated tube.

3. The high-pressure resistant sterile quick connector according to claim 1, characterized in that, The infinite snap fastener assembly (6) includes mounting grooves (21) evenly spaced at the bottom of the outer circumference of the protective sleeve (4), and each mounting groove (21) has a guide opening (22) at its bottom. Two guide holes (23) are located above and below the guide openings (22) at the bottom of the mounting grooves (21). Guide rods (604) are inserted into the interior of each guide hole (23), and one end of each guide rod (604) is fixed with the same locking tooth block (601). One side of the locking tooth block (601) is connected to the mounting groove. The mounting groove (21) is equipped with a pressing component. The top of the protective inner sleeve (9) is provided with equally spaced docking slots (7), and the number of docking slots (7) is the same as the number of mounting grooves (21). A guide groove (8) is provided between the inner wall of one side of the docking slot (7) and the outer wall of the protective inner sleeve (9). The inner wall of the other side of the docking slot (7) is provided with equally spaced locking tooth grooves (17). The locking tooth block (601) is inserted into the interior of the docking slot (7) and meshes with the locking tooth groove (17).

4. The high-pressure resistant sterile quick connector according to claim 3, characterized in that, The pressing assembly includes a pressing plate (602) rotatably connected to the inner wall of the mounting groove (21), and a spring (603) is fixed between the top of one side of the pressing plate (602) and the top of one side of the mounting groove (21). A connecting groove (605) is provided at the bottom of the pressing plate (602). A traction plate (607) passing through the connecting groove (605) is rotatably connected to one side of the toothed block (601). The position of the traction plate (607) corresponds to the position of the guide groove (8). Movable grooves (606) are provided between both ends of the connecting groove (605) and the outer walls of both ends of the pressing plate (602). A pin inserted into the movable groove (606) is rotatably connected to one end of the traction plate (607).

5. A high-pressure resistant sterile quick connector according to claim 4, characterized in that, The top of the protective inner sleeve (9) is provided with positioning holes (19) that are evenly spaced and distributed in a ring. The bottom corner of the protective outer sleeve (4) is fixed with positioning rods (18) that are evenly spaced and adapted to the inner wall of the positioning holes (19). The positions of the positioning holes (19) and the docking slots (7) are staggered.

6. A high-pressure resistant sterile quick connector, comprising a female connector (1) and a male connector (2) similar in specifications to the female connector (1), characterized in that, The female connector (1) and the male connector (2) are both provided with a flexible connector (3) with a buckle at the top center and at the bottom center, respectively, which can be connected to pipes of different sizes. The center of the female connector (1) and the center of the male connector (2) are both provided with a flow channel hole communicating with the flexible connector (3). The male connector (2) and the female connector (1) are provided with a sterile connection device at the top center and the bottom center of the female connector (1). The sterile connection device includes an annular groove at the top center of the male connector (2) and the bottom center of the female connector (1). 12) and sealing components, the outer circumferential wall of the female connector (1) is fixed with a protective outer sleeve (4), and the cross-section of the protective outer sleeve (4) is L-shaped. The thickness of the protective outer sleeve (4) is greater than the thickness of the female connector (1). The outer circumferential wall of the male connector (2) is fixed with a protective inner sleeve (9) of the same thickness as the male connector (2). The outer circumferential wall of the protective inner sleeve (9) is matched with the bottom of the inner circumferential wall of the protective outer sleeve (4). There are infinitely fastening components (6) that are evenly distributed in a ring between the bottom of the protective outer sleeve (4) and the top of the protective inner sleeve (9). The sealing assembly includes an outer cone (15) fixed at the middle position of the inner wall of the annular groove (12) on the male connector (2) and an inner cone (14) fixed at the middle position of the inner wall of the annular groove (12) on the female connector (1). The inner wall of the annular groove (12) on the male connector (2) is provided with a first annular sealing gasket (16) sleeved on the outside of the outer cone (15). A barrier membrane (11) is provided between the top of the first annular sealing gasket (16) and the top of the outer cone (15) and the bottom of the inner cone (14).

7. A high-pressure resistant sterile quick connector according to claim 6, characterized in that, The inner cone (14) and the outer cone (15) are respectively provided with liquid channels communicating with the flow channel hole. The liquid channels are also connected to the connector hose (3). The outer wall of the outer cone (15) is provided with multiple annular protrusions (20) of different specifications. The inner wall of the inner cone (14) is provided with multiple slots that are compatible with the specifications of the protrusions (20). The inner circumference of the first annular sealing gasket (16) is compatible with the outer circumference of the inner cone (14).

8. A high-pressure resistant sterile quick connector, comprising a female connector (1) and a male connector (2) similar in specifications to the female connector (1), characterized in that, The female connector (1) and the male connector (2) are both provided with a flexible connector (3) with a buckle at the top center and at the bottom center, respectively, which can be connected to pipes of different sizes. The center of the female connector (1) and the center of the male connector (2) are both provided with a flow channel hole communicating with the flexible connector (3). The male connector (2) and the female connector (1) are provided with a sterile connection device at the top center and the bottom center of the female connector (1). The sterile connection device includes an annular groove at the top center of the male connector (2) and the bottom center of the female connector (1). 12) and sealing components, the outer circumferential wall of the female connector (1) is fixed with a protective outer sleeve (4), and the cross-section of the protective outer sleeve (4) is L-shaped. The thickness of the protective outer sleeve (4) is greater than the thickness of the female connector (1). The outer circumferential wall of the male connector (2) is fixed with a protective inner sleeve (9) of the same thickness as the male connector (2). The outer circumferential wall of the protective inner sleeve (9) is matched with the bottom of the inner circumferential wall of the protective outer sleeve (4). There are infinitely fastening components (6) that are evenly distributed in a ring between the bottom of the protective outer sleeve (4) and the top of the protective inner sleeve (9). The sealing assembly includes an outer cone (15) fixed at the middle position of the inner wall of the annular groove (12) on the male connector (2) and an inner cone (14) fixed at the middle position of the inner wall of the annular groove (12) on the female connector (1). The inner walls of the two annular grooves (12) are respectively provided with a first annular sealing gasket (16) sleeved on the outside of the inner cone (14) and the outside of the outer cone (15). A barrier membrane (11) is provided between the top of the first annular sealing gasket (16) and the top of the outer cone (15) and the bottom of the inner cone (14).

9. A high-pressure resistant sterile quick connector according to claim 8, characterized in that, The barrier membrane (11) is made of PTFE membrane with a pore size of 0.2 μm, and the barrier membrane (11) is folded into a double layer. One layer of the barrier membrane (11) is welded to the end face of the sterile connection device using a false welding process, and completely covers the first annular sealing gasket (16), the inner cone (14) and the outer cone (15). A breathable membrane (10) with adhesive backing is pasted on the folded, unwelded layer of the barrier membrane (11), and the breathable membrane (10) is folded and overlaps with the barrier membrane (11). The folded portion of the breathable membrane (10) The membrane slots (13) extend to the other side of the sterile connection device. Both sides of the top of the female connector (1) and the top of the male connector (2) are provided with through-membrane slots (13). One end of the barrier membrane (11) and one end of the breathable membrane (10) pass through the inside of the membrane slots (13). The ends of the membrane slots (13) are all designed as bevels. The ends of the membrane slots (13) are all clamped with limit seats (5). The barrier membrane (11) and the breathable membrane (10) are pressed into the inside of the membrane slots (13) by the limit seats (5).

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