Skin oil control composition and use thereof

Abstract

The present application relates to the field of daily chemicals, and discloses a skin oil control composition which has a synergistic inhibitory effect on 5alpha-reductase in skin tissue, thereby achieving inhibition of sebaceous glands to secrete sebum, and is composed of saw palm extract, radix astragali extract and coltsfoot leaf extract components; the application of the oil control composition for hair includes the following main components: the skin oil control composition, auxiliary oil control additives, base cleaning agent, amino acid surfactant, auxiliary surfactant, thickening agent, scalp conditioner and pearl agent. The effective components of the product can form a synergistic effect, effectively inhibit 5alpha-reductase, and further inhibit the secretion of sebum in the sebaceous glands in the skin tissue, so as to achieve the effect of long-acting maintenance of scalp health and clean and beautiful hair.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of daily chemicals, in particular to a skin oil control composition and application thereof. BACKGROUND

[0002] Sebum plays a very important role in maintaining the health of the scalp and hair, but excessive sebum can form an oily scalp, causing symptoms such as dandruff, itching, and can also accelerate the rate of hair oiling and collapse, affecting the temperament and appearance of a person. With the acceleration of the pace of life in today's society, the imbalance of dietary structure, and the increase of life pressure, the problem of hair oiling is becoming more and more common. The sebaceous gland cells in human skin are in a state of secreting sebum at all times, and one of the important factors affecting the secretion of sebum by sebaceous glands is the activity of 5α-reductase.

[0003] Traditional oil control shampoos mainly reduce the content of silicone oil, oil, conditioning agent in the shampoo, or increase the content of surfactant, to enhance the cleaning effect of oil, and achieve the effect of oil control, but lack deeper regulation of the scalp oiling. The reduction of oil content in shampoo can cause hair dehydration, hairiness, dryness and other problems, and also cause sebaceous glands to secrete more sebum, further affecting the health of the scalp.

[0004] In recent years, plant herbal ingredients have been increasingly widely used in the daily chemical industry. The more commonly used traditional Chinese medicine ingredients include ginger, radix polygoni multiflori, saw palm, and radix astragali, and the active substances thereof can have various care effects on the scalp and hair.

[0005] Existing technology research shows that saw palm has the activity of inhibiting 5α-reductase and the effect of preventing seborrheic alopecia, so it can inhibit the secretion of sebum by sebaceous glands.

[0006] Patent No. KR1020140011239A discloses that the crude extract, polar solvent soluble extract or non-polar solvent soluble extract of radix astragali has the activity of inhibiting 5α-reductase expression. Radix astragali is a tonic medicine in traditional Chinese medicine, but it is prone to move, and it can be used on the surface and inside, and it has the function of promoting hair growth. On the surface, it can tonify qi and consolidate the exterior, and it can promote the outward diffusion of external toxins; inside, it can tonify the middle qi to raise yang and lift the sinking, so that "qi is solid and sinking is removed"; upward, it can raise qi and lower water to tonify qi and promote blood circulation. The extract of radix astragali can not only supplement nutrients for hair, but also promote blood circulation. The application of saw palm or radix astragali in shampoo mainly involves the addition of various plant ingredient additives to solve the problem of hair loss of users. There are problems such as too many traditional Chinese medicine ingredients in the formula, complex preparation process, and the active substances in the formula are difficult to stay in the shampoo, which is a daily use rinse-off product, and it is difficult to fully play the role of oil control.

[0007] Although many components disclosed in the prior art can inhibit the secretion of sebum from sebaceous glands, how to more effectively inhibit the secretion of sebum from sebaceous glands, solve the problem of excessive sebum on the scalp, and achieve the effect of protecting the health, cleanliness and beauty of hair has become a difficult problem in the field of daily chemicals. SUMMARY

[0008] In view of the deficiencies of the prior art, the technical problem solved by the present application is how to better inhibit the secretion of sebum from sebaceous glands, solve the problem of excessive sebum on the scalp, and achieve the effect of healthy scalp and clean and beautiful hair.

[0009] To solve the above technical problems, the technical solution provided by the present application is a skin oil control composition which has a synergistic inhibitory effect on 5α-reductase in skin tissue, thereby inhibiting the secretion of sebum from sebaceous glands, and is composed of the following components by mass fraction:

[0010] Saw palmetto extract 4-5 parts;

[0011] Radix astragali extract 3-4 parts;

[0012] Coltsfoot leaf extract 1-3 parts.

[0013] The saw palmetto extract is a combination of lipid-soluble extract and alcohol-water extract of saw palmetto;

[0014] The radix astragali extract is an alcohol-water extract;

[0015] The coltsfoot leaf extract is an alcohol-water extract.

[0016] To solve the above technical problems, another technical solution provided by the present application is a hair oil control composition containing the above-mentioned skin oil control composition, which is composed of the following components by mass fraction:

[0017] Skin oil control composition 1-10 parts;

[0018] Auxiliary oil control aid 1-5 parts;

[0019] The auxiliary oil control aid is composed of the following components by mass fraction:

[0020] Oligoarginine chitosan 1-3 parts;

[0021] Hydrolyzed sodium hyaluronate composition 1-8 parts.

[0022] The hydrolyzed sodium hyaluronate has a molecular weight of ≤10KDa.

[0023] Oligoarginine is an artificial synthetic high-efficiency cationic cell-penetrating peptide, which can carry various substances into cells or transmit between cells, and a large number of positive charges can be adsorbed on the surface of hair. Oligoarginine chitosan has the effect of promoting the transdermal absorption of small molecular substances, and also has a certain sustained-release effect.

[0024] Sodium hyaluronate is a skin inherent biological substance, which has good moisturizing effect, and small sodium hyaluronate can penetrate into the epidermis of the skin, promote the supply of skin nutrition and excretion of waste.

[0025] To solve the above technical problems, another technical scheme provided by the present application is a shampoo containing the above hair oil control composition, which comprises the following components:

[0026] Hair oil control composition 0.5-4.5 parts;

[0027] Matrix cleaner 3.5-10.8 parts;

[0028] Amino acid surfactant 6.5-15.0 parts;

[0029] Co-surfactant 3.5-5.8 parts;

[0030] Thickening agent 0.3-1.0 parts;

[0031] Scalp conditioner 0.5-1.5 parts;

[0032] Pearlescent agent 0.5-1.2 parts;

[0033] Other auxiliary agent 0.4-2.0 parts;

[0034] pH adjuster in proper amount;

[0035] Deionized water in proper amount.

[0036] Further, the matrix cleaner is at least one of fatty alcohol polyether sulfate, monoalkyl sulfate, fatty acyl methyl taurate; preferably, the cleaner is fatty alcohol polyether sulfate. Further, the fatty alcohol polyether sulfate is sodium lauryl ether sulfate.

[0037] The amino acid surfactant is sodium lauroyl glutamate;

[0038] The co-surfactant is at least one of fatty acyl amphoteric acetate, fatty acyl propyl betaine, fatty acyl amido hydroxypropyl sulfobetaine; preferably, the co-surfactant is fatty acyl propyl betaine, further, the fatty acyl propyl betaine is lauroyl propyl betaine.

[0039] The thickening agent is at least one of carbomer, ammonium chloride, sodium chloride, sodium carboxymethyl cellulose;

[0040] The scalp conditioner is at least one of amino acids, allantoin, nicotinamide, keratin;

[0041] The pearl agent is at least one of ethylene glycol distearate, glycerol monostearate;

[0042] The other auxiliary agent is at least one of antistatic agent, preservative, essence.

[0043] Further, the antistatic agent is at least one of polyquaternium, guar hydroxypropyltrimonium chloride; the preservative is at least one of phenoxyethanol, ethylhexylglycerin, sodium benzoate, hydroxybenzoate, hydroxyphenyl ethyl ester.

[0044] Beneficial effects:

[0045] (1) By saw palm extract, radix astragali extract, coltsfoot leaf extract in a specific ratio, the effective components between the components form a synergistic effect, which can effectively inhibit 5α-reductase, and then inhibit the secretion of sebaceous gland oil in skin tissue;

[0046] (2) By compounding oligoarginine chitosan and sodium hyaluronate in the hair oil control composition, the effective components in saw palm extract, radix astragali extract and coltsfoot leaf extract are fully absorbed by the scalp, and then play a synergistic oil control effect in the scalp tissue, achieving the effect of long-acting maintenance of scalp health and clean and beautiful hair. BRIEF DESCRIPTION OF DRAWINGS

[0047] Figure 1 It is a schematic diagram of skin oil content at different times for different compositions;

[0048] Figure 2 It is a schematic diagram of scalp oil content at different times for different shampoos used temporarily;

[0049] Figure 3 It is a schematic diagram of scalp oil content at different times for different shampoos used persistently. DETAILED DESCRIPTION

[0050] The specific embodiments of the present application will be further described below in conjunction with the accompanying drawings, but are not limited to the present application.

[0051] The plant extracts in the following examples and comparative examples can be obtained by the basic extraction method, and the remaining raw materials, reagents or devices can be obtained from conventional commercial channels, or can be obtained by existing known methods, unless otherwise specified.

[0052] I. Skin oil control composition examples

[0053] Example 1

[0054] A skin oil control composition comprising the following components by mass fraction:

[0055] Saw palmetto extract 4 parts;

[0056] Radix astragali extract 4 parts;

[0057] Coltsfoot leaf extract 1 part.

[0058] Example 2

[0059] A skin oil control composition comprising the following components by mass fraction:

[0060] Saw palmetto extract 5 parts;

[0061] Radix astragali extract 3 parts;

[0062] Coltsfoot leaf extract 3 parts.

[0063] Example 3

[0064] A skin oil control composition comprising the following components by mass fraction:

[0065] Saw palmetto extract 4.5 parts;

[0066] Radix astragali extract 3.5 parts;

[0067] Coltsfoot leaf extract 2 parts.

[0068] The preparation method of the skin oil control composition in the above-mentioned examples 1 to 3 is as follows:

[0069] (1) A certain amount of saw palmetto, radix astragali and coltsfoot leaves are respectively subjected to high-speed pulverization and 200-mesh screening treatment. The saw palmetto powder is extracted with ethanol with a volume concentration of 70%, and the filtrate and the residue are separated. The residue is subjected to secondary extraction with ethyl acetate to obtain a fat-soluble saw palmetto extract. The filtrate is subjected to concentration treatment to obtain an alcohol-water saw palmetto extract. The obtained fat-soluble saw palmetto extract and alcohol-water saw palmetto extract are mixed to obtain saw palmetto extract.

[0070] (2) The radix astragali powder and the coltsfoot leaf powder are respectively extracted with 70% ethanol, and the extracted filtrate is collected and subjected to concentration treatment to obtain radix astragali extract and coltsfoot leaf extract.

[0071] (3) The saw palmetto extract, the radix astragali extract and the coltsfoot leaf extract are mixed to obtain a skin oil control composition.

[0072] II. Hair oil control composition examples

[0073] Example 4

[0074] A hair oil control composition comprising the following components by mass fraction:

[0075] Serenoa repens extract 4 parts;

[0076] Radix astragali extract 4 parts;

[0077] Cola acuminata leaf extract 1 part;

[0078] Skin oil control composition 1 part;

[0079] Auxiliary oil control aid 5 parts.

[0080] Example 5

[0081] A hair oil control composition comprising the following components by mass fraction:

[0082] Serenoa repens extract 5 parts;

[0083] Radix astragali extract 3 parts;

[0084] Cola acuminata leaf extract 3 parts;

[0085] Skin oil control composition 10 parts;

[0086] Auxiliary oil control aid 1 part.

[0087] Example 6

[0088] A hair oil control composition comprising the following components by mass fraction:

[0089] Serenoa repens extract 4.5 parts;

[0090] Radix astragali extract 3.5 parts;

[0091] Cola acuminata leaf extract 2 parts;

[0092] Skin oil control composition 5 parts;

[0093] Auxiliary oil control aid 3 parts.

[0094] The preparation method of the hair oil control composition in one of the above Examples 4 to 6 is as follows:

[0095] (1) Add an appropriate amount of oligoarginine to a certain amount of Cola acuminata leaf extract for use;

[0096] (2) Mix and stir a certain amount of Serenoa repens extract and Radix astragali extract according to the ratio, and homogenize at a speed of 5000-10000 rpm for more than 5 min;

[0097] (3) After homogenization, add a certain amount of hydrolyzed sodium hyaluronate powder and stir evenly;

[0098] (4) While stirring, add the Cola acuminata leaf extract containing oligoarginine chitosan dropwise, and continue stirring for more than 30 min after the dropwise addition is completed to obtain a hair oil control composition.

[0099] Comparative Examples 1 to 4

[0100] Different from Examples 1 to 3, the plant extract ingredient in the comparative examples is a single solvent extract of a single plant. The specific plant extract is shown in Table 1 below.

[0101] Table 1

[0102]

[0103]

[0104] Comparative Examples 5 to 7

[0105] Different from Examples 1 to 3, the plant extract ingredient in the comparative examples is a combination of two plant extracts. The specific plant extract combination and its ratio are shown in Table 2 below.

[0106] Table 2

[0107] Comparative Example Plant Extract Parts by mass Comparative Example 5 Serenoa repens extract: Astragalus extract 1：1 Comparative Example 6 Serenoa repens extract: Cola extract 1：1 Comparative Example 7 Astragalus extract: Cola extract 1：1

[0108] III. Efficacy Experiment of the Composition

[0109] (I) Inhibition of 5α-reductase Activity

[0110] The plant extracts of each of the above examples and comparative examples were pretreated to obtain pretreated sample solutions, wherein the effective concentration of the single extract or extract combination solution was 1.0%. 20 uL of each of the sample solution and negative control (normal saline) was added to the enzyme reaction system for catalysis for 10 min, and the enzyme reaction system was carried out at 37°C and pH = 6.0. The absorbance value was measured at 340 nm using a UNICOR (Shanghai) Instrument Co., Ltd. UV-2800 UV-visible spectrophotometer, and the average of three absorbance values was used to calculate the enzyme activity.

[0111] Enzyme activity U = (absorbance change A / 0.01*reaction time t)*dilution factor D.

[0112] The results of the enzyme activity of 5α-reductase are shown in Table 3 below:

[0113] Table 3

[0114]

[0115]

[0116] From Table 3, it can be seen that, compared with the negative control experiment, the enzyme activity values of the saw palmetto extract, the radix astragali extract, and the coltsfoot leaf extract composition in Examples 1 to 3 are all low, i.e., the compositions have a significant inhibitory effect on 5α-reductase. Comparing the effects of the plant extracts in Example 1 and Comparative Examples 1 to 4, it can be found that the enzyme activity values of the experimental groups in which the three plant extracts are added alone are all lower than that of the negative control group, i.e., the three plant extracts all have an inhibitory effect on 5α-reductase, and the effect of the saw palmetto extract, the radix astragali extract, and the coltsfoot leaf extract composition is better than that of the liposoluble saw palmetto extract, which is better than that of the alcohol-water saw palmetto extract, which is better than that of the radix astragali extract, and is significantly better than that of the coltsfoot leaf extract.

[0117] Comparing the enzyme activity values after the effects of the plant extracts in Example 1 and Comparative Examples 5 to 7, it can be found that the effect of the saw palmetto extract, the radix astragali extract, and the coltsfoot leaf extract composition is better than that of the saw palmetto extract and the radix astragali extract composition, which is better than that of the saw palmetto extract and the coltsfoot leaf extract composition, and is significantly better than that of the radix astragali extract and the coltsfoot leaf extract composition. Comparing the test results of the test samples in Example 1 and Examples 4 to 6, it can be found that the enzyme activity values do not change significantly after the addition of the auxiliary oil control adjuvant.

[0118] It can be seen that the single extracts of saw palmetto, radix astragali, and coltsfoot leaf all have a certain effect as 5α-reductase inhibitory active ingredients, and the effect of the saw palmetto extract is better than that of the radix astragali extract, which is better than that of the coltsfoot leaf extract, and the inhibitory effect on 5α-reductase can be significantly improved after the combination of the three plant extracts. However, the auxiliary oil control adjuvant does not have a significant effect in the in-vitro 5α-reductase activity inhibition experiment of the oil control composition.

[0119] (B) Skin oil control experiment

[0120] The plant extracts in each of the above examples and comparative examples were pretreated to obtain pretreated test sample solutions, and the effective concentrations of the single extracts or extract compositions were all 1.0%. The blank control group was pure water without any extract. Thirty-three testers with more oil on the forehead skin were selected for the test, and each group of three testers was selected. The average value of the oil content of the skin of the three testers was tested. After simple cleansing, the testers completely immersed 3.0 cm*3.0 cm of water-absorbing cotton in the extract solution or pure water, and then applied the water-absorbing cotton to the forehead skin for 10 min. The oil content of the test area was tested by a multifunctional skin tester at 1 h, 3 h, 5 h, 7 h, and 9 h. The principle of the equipment is that the probe contains an extinction adhesive tape, and the transparency of the tape increases after absorbing oil. The oil content of the scalp can be reflected by the light transmission amount of the probe, and the measurement value is μg / cm 2 . The skin oil content at different times was obtained, as shown in Figure 1 .

[0121] By Figure 1 It can be seen that, comparing the skin oil content of the skin after 1h, 3h, 5h, 7h, 9h of the blank control group and the skin of Comparative Examples 1-7, the skin oil content of the skin added with each plant extract is lower than that of the blank control group, but the effect mainly reflects before 5h, and after 5h, the skin oil content can still reach a high level. Comparing Examples 1-3 and Comparative Examples 1-4, the skin oil content of Examples 1-3 is significantly lower than that of Comparative Examples 1-4. Further comparing the skin oil content of Example 1 and Comparative Examples 4-7, it can be found that the skin oil content of Example 1 after 3h is significantly lower than that of Comparative Examples 4-7 at the corresponding time. Comparing Example 4 and Example 1, it can be found that after the oil control composition is compounded with the oil control auxiliary agent, the skin oil content value after 5h is significantly reduced, and the skin oil content at 9h is reduced by 43% compared with the blank control group.

[0122] Therefore, it can be seen that the control effect of the saw palm extract, the astragalus extract, and the coltsfoot leaf extract composition on the skin oiliness is obviously better than that of the three plant extracts acting alone, and further better than that of the plant extract composition obtained by compounding the three plant extracts two by two. Specifically, on the one hand, the saw palm extract, the astragalus extract, and the coltsfoot leaf extract composition have a significant oil control effect, which can effectively control the oil amount of the skin after the action, and on the other hand, the saw palm extract, the astragalus extract, and the coltsfoot leaf extract composition have a longer oil control effect, which can effectively control the oil amount of the skin for a longer time after the action. Further, compounding oligoarginine chitosan and sodium hyaluronate auxiliary agents in the three plant extract compositions can have a synergistic effect, thereby further fully playing the role of the long-acting oil control composition.

[0123] IV. Shampoo Examples

[0124] Example 7

[0125] A shampoo containing a hair oil control composition, comprising the following components:

[0126] Hair oil control composition 0.5 parts;

[0127] Sodium lauryl ether sulfate 10.8 parts;

[0128] Sodium lauroyl glutamate 6.5 parts;

[0129] Lauroyl propyl betaine 5.8 parts;

[0130] Carbomer 0.3 parts;

[0131] Keratin 1.5 parts;

[0132] Ethylene glycol distearate 0.5 parts;

[0133] Phenoxyethanol 2.0 parts;

[0134] pH adjuster q.s.

[0135] Deionized water q.s.

[0136] Example 8

[0137] A shampoo containing the hair oil control composition, comprising the following components:

[0138] Sodium laureth sulfate 3.5 parts;

[0139] Sodium lauroyl glutamate 15.0 parts;

[0140] Lauroyl propyl betaine 3.5 parts;

[0141] Carbomer 1.0 part;

[0142] Keratin 0.5 part;

[0143] Ethylene glycol distearate 1.2 parts;

[0144] Phenoxyethanol 0.4 part;

[0145] pH adjuster q.s.

[0146] Deionized water q.s.

[0147] Example 9

[0148] A shampoo containing the hair oil control composition, comprising the following components:

[0149] Hair oil control composition 2 parts;

[0150] Sodium laureth sulfate 5 parts;

[0151] Sodium lauroyl glutamate 12 parts;

[0152] Lauroyl propyl betaine 4 parts;

[0153] Carbomer 0.5 part;

[0154] Keratin 1 part;

[0155] Ethylene glycol distearate 0.8 parts;

[0156] Phenoxyethanol 1 part;

[0157] pH adjuster q.s.

[0158] Deionized water q.s.

[0159] Comparative Example 8

[0160] A shampoo containing a skin oil-controlling composition, comprising the following components:

[0161] Skin oil-controlling composition 0.5 parts;

[0162] Sodium lauryl ether sulfate 10.8 parts;

[0163] Sodium lauroyl glutamate 6.5 parts;

[0164] Lauroyl propyl betaine 5.8 parts;

[0165] Carbomer 0.3 parts;

[0166] Keratin 1.5 parts;

[0167] Ethylene glycol distearate 0.5 parts;

[0168] Phenoxyethanol 2.0 parts;

[0169] pH adjuster q.s.;

[0170] Deionized water q.s.

[0171] The shampoo containing a hair oil-controlling composition or a skin oil-controlling composition in the above Examples 7-9 and Comparative Example 8 is prepared as follows:

[0172] (1) Add deionized water, base cleanser, amphoteric surfactant, amino acid surfactant, carbomer to water, heat to 80°C to dissolve and disperse uniformly;

[0173] (2) Add hydroxypropyl guar gum, hydroxypropyltrimonium chloride, ethylene glycol distearate in sequence, stir to dissolve uniformly, and cool to 45°C;

[0174] (3) Add keratin, dimethicone, oil-controlling composition, phenoxyethanol, stir to dissolve uniformly, and obtain the finished product;

[0175] (4) Adjust the pH to between 4.0 and 6.5.

[0176] Comparative Example 9

[0177] A shampoo, comprising the following components:

[0178] Sodium lauryl ether sulfate 9.8 parts;

[0179] Sodium lauroyl glutamate 8.2 parts;

[0180] Lauroyl propyl betaine 2.4 parts;

[0181] Carbomer 0.2 parts;

[0182] Ethylene glycol distearate 0.8 parts;

[0183] Keratin 0.3 part;

[0184] Polyquaternium-7 0.05 part;

[0185] Phenoxyethanol 0.5 part;

[0186] Fragrance 0.2 part;

[0187] pH adjuster appropriate amount;

[0188] Deionized water appropriate amount.

[0189] Comparative Example 10

[0190] A shampoo comprising the following components:

[0191] Sodium laureth sulfate 9.8 parts;

[0192] Sodium lauroyl glutamate 8.2 parts;

[0193] Lauroyl propyl betaine 2.4 parts;

[0194] Carbomer 0.2 part;

[0195] Ethylene glycol distearate 0.8 part;

[0196] Dimethicone 0.5 part;

[0197] Keratin 0.3 part;

[0198] Polyquaternium-7 0.05 part;

[0199] Phenoxyethanol 0.5 part;

[0200] Fragrance 0.2 part;

[0201] pH adjuster appropriate amount;

[0202] Deionized water appropriate amount.

[0203] IV. Evaluation of Shampoo Effect

[0204] (I) Test of short-term oil control effect

[0205] A number of volunteers with oily hair were recruited to use the shampoo of Examples 6-8 and Comparative Examples 8-10 respectively, and the change of scalp oil was tested at 8h, 24h, 48h and 72h after washing the hair. The test score index and test data are shown in Table 4.

[0206] The detection method of oil content: the detection equipment used is multifunctional skin tester, the principle of which is that the probe contains extinction adhesive tape, the transparency of which increases after absorbing oil, and the oil content of the scalp can be reflected by the light transmittance of the probe. The sampling points are at least three (left and right vertex and vertex position) each time, and the average value is the measurement value, with the unit of μg / cm 2 The measurement values are shown in Table 4.

[0207] Table 4

[0208]

[0209]

[0210] From Table 4 above and Figure 2 It can be seen that, by comparing Examples 6 to 9 and Comparative Examples 8 to 10, there is no significant difference in the oil content of the scalp of the testers before using the shampoo formulations of each experimental group for 8 hours, but the oil content of the scalp of the testers using the shampoo formulations containing saw palmetto extract, radix astragali extract and coltsfoot leaf extract composition is significantly lower than that of the experimental group of Comparative Example after 8 hours. Among them, the oil output of the scalp of Examples 6 to 8 after 8 hours is also relatively low compared with Comparative Example 8.

[0211] Therefore, it can be seen that the addition of saw palmetto extract, radix astragali extract and coltsfoot leaf extract composition in the shampoo formulation can effectively inhibit the oil output of the scalp, thereby achieving the effect of shampooing and oil control, and the addition of oligoarginine chitosan and sodium hyaluronate additives can further improve the oil control effect of the shampoo with the added hair oil control composition formulation.

[0212] (II) Evaluation of long-lasting oil control effect and hair quality

[0213] A number of oily hair volunteers were recruited to use the shampoo formulations of Examples 6 to 8 and Comparative Examples 8 to 10, respectively, and wash their hair every 48 hours. After 28 days of use, the changes in the oil content of the scalp were tested at 8 hours, 24 hours, 48 hours and 72 hours, and the data are shown in Table 5. The hair quality was scored 72 hours after shampooing, and the hair quality scoring indicators and test data are as follows:

[0214] Scoring indicators:

[0215] The greasy feeling was evaluated by scoring 1 to 5, with 1 indicating very greasy, 2 indicating relatively greasy, 3 indicating general, 4 indicating good, and 5 indicating excellent. The dryness degree was evaluated by scoring 1 to 5, with 1 indicating very dry, 2 indicating dry, 3 indicating general, 4 indicating good, and 5 indicating excellent. The average value of each group was taken, with one decimal point, and the results are shown in Table 6.

[0216] Table 5

[0217] Sebum content Example 6 Example 7 Example 8 Comparative Example 8 Comparative Example 9 Comparative Example 10 8h 24.6 23.4 20.8 26.5 44.2 50.6 24h 42.2 42.3 40.4 46.6 81.8 90.2 48h 68.7 68.9 66.8 70.1 101.4 120.6 72h 75.5 72.6 70.4 95.9 121.7 143.4

[0218] From the above Table 5 and Figure 3 It can be seen that, comparing Examples 6-8 with Comparative Examples 8-10, after the testers continuously used the shampoo formulations of each experimental group for 28 days, the testers continued to test the changes in the oiliness of the scalp after using different shampoo formulations, and the oiliness of the scalp of the testers in Examples 6-8 was significantly lower than that of the testers in Comparative Examples 8-10 after 8h, 24h, 48h and 72h, wherein the oiliness of the scalp of Examples 6-8 was relatively low after 48h, and the growth trend of the oiliness of the scalp was significantly slowed down.

[0219] Therefore, it can be seen that the addition of saw palmetto extract, radix astragali extract and coltsfoot leaf extract composition in the shampoo formulation can significantly control the oil output of the scalp after long-term use, and further compounding oligoarginine chitosan and sodium hyaluronate oil control additives in the shampoo can effectively control the growth trend of the oiliness of the scalp, maintain the oil balance of the scalp, and thus avoid the subsequent increase in the oiliness of the scalp caused by the use of over-cleansing shampoo.

[0220] Table 6

[0221] Hair quality Example 6 Example 7 Example 8 Comparative Example 8 Comparative Example 9 Comparative Example 10 Oily degree 4 5 4 3 4 1 Dryness degree 5 4 5 5 2 5

[0222] From the above Table 6, it can be seen that, comparing Examples 6-8 with Comparative Examples 8-10, after the testers continuously used the shampoo formulations of each experimental group for 28 days, the testers continued to test the greasy degree and dryness degree of the hair after using different shampoo formulations for 72h, wherein Examples 6-8 can effectively control the greasy degree of the hair, and will not cause the hair to be excessively dry. Therefore, it can be seen that the addition of hair oil control composition in the shampoo formulation can long-term effectively inhibit the oil output of the scalp, and at the same time can avoid the subsequent oiliness of the hair caused by the use of over-cleansing shampoo or the use of silicone oil-containing shampoo ingredients.

[0223] Therefore, it can be seen that the application of the oil control composition of saw palmetto extract, radix astragali extract and coltsfoot leaf extract composition compounded with oligoarginine chitosan and sodium hyaluronate in shampoo can effectively inhibit the oiliness of the scalp caused by excessive secretion of oiliness of the scalp, and thus solve the problem of poor appearance caused by oily hair.

[0224] The above describes the embodiments of the present application in detail in combination with the drawings, but the present application is not limited to the described embodiments. For those skilled in the art, various changes, modifications, replacements and variations of the embodiments without departing from the principles and spirits of the present application still fall within the protection scope of the present application.

Claims

1. A method for preparing a skin oil-controlling composition, characterized in that, The specific preparation steps are as follows: (1) A certain amount of saw palmetto, astragalus and coltsfoot leaves were pulverized at high speed and sieved through a 200-mesh screen. The saw palmetto powder was extracted with 70% ethanol by volume. The filtrate and the residue were separated by filtration. The residue was extracted a second time with ethyl acetate to obtain a fat-soluble saw palmetto extract. The filtrate was concentrated to obtain an alcohol-water saw palmetto extract. The fat-soluble saw palmetto extract and the alcohol-water saw palmetto extract were mixed to obtain the saw palmetto extract. (2) Extract the powder of Astragalus membranaceus and the powder of Tussilago farfara with 70% ethanol respectively, collect the filtrate of the extract, and concentrate it to obtain Astragalus membranaceus extract and Tussilago farfara extract. (3) A skin oil-controlling composition is obtained by mixing saw palmetto extract, astragalus extract and coltsfoot leaf extract.

2. The skin oil-controlling composition obtained by the preparation method according to claim 1, characterized in that, It has a synergistic inhibitory effect on 5α-reductase in skin tissue, thereby inhibiting sebum secretion from sebaceous glands. It consists of the following components by weight: 4-5 parts of saw palmetto extract; 3-4 parts of Astragalus extract; Coltsfoot leaf extract, 1-3 parts.

3. The skin oil-controlling composition according to claim 2, characterized in that, The saw palmetto extract is a combination of a fat-soluble extract and an alcohol-water extract of the saw palmetto; the astragalus extract is an alcohol-water extract; and the coltsfoot leaf extract is an alcohol-water extract.

4. A hair oil-control composition comprising the skin oil-control composition of claim 3, characterized in that, It consists of the following components by mass: 1-10 parts of skin oil-control composition; 1-5 parts of auxiliary oil-controlling agent, wherein the auxiliary oil-controlling agent is composed of the following components by weight: Oligomeric arginine chitosan 1-3 parts; 1-8 parts of hydrolyzed sodium hyaluronate; The specific preparation steps of the hair oil-controlling composition are as follows: (1) Add an appropriate amount of oligo-arginine chitosan to a certain amount of coltsfoot leaf extract for later use; (2) Mix a certain amount of saw palmetto extract and astragalus extract in proportion and homogenize at 5000-10000 rpm for more than 5 minutes; (3) After homogenization, add a certain amount of hydrolyzed sodium hyaluronate powder and stir evenly; (4) While stirring, add the coltsfoot leaf extract containing oligoarginine chitosan. After the addition is complete, continue stirring for more than 30 minutes to obtain a hair oil control composition.

5. The hair oil-controlling composition according to claim 4, characterized in that, The hydrolyzed sodium hyaluronate has a molecular weight ≤10 kDa.

6. A shampoo containing the hair-controlling composition of claim 5, characterized in that, Includes the following components: Hair oil-controlling composition: 0.5–4.5 parts; 3.5–10.8 parts of matrix cleaner; 6.5–15.0 parts of amino acid surfactant; 3.5–5.8 parts of auxiliary surfactant; Thickener 0.3–1.0 parts; Scalp conditioner 0.5–1.5 parts; Pearlizing agent 0.5–1.2 parts; Other additives: 0.4–2.0 parts; pH adjuster in appropriate amount; Add an appropriate amount of deionized water.

7. The shampoo according to claim 6, characterized in that, The matrix cleaner is at least one of fatty alcohol polyether sulfate, monoalkyl sulfate, and fatty acylmethyl taurate; The amino acid surfactant is sodium lauroyl glutamate; The auxiliary surfactant is at least one of fatty acyl amphoteric acetate, fatty acyl propyl betaine, and fatty amide hydroxypropyl sulfobetaine. The thickener is at least one of carbomer, ammonium chloride, sodium chloride, and sodium carboxymethyl cellulose. The scalp conditioning agent is at least one of amino acids, allantoin, nicotinamide, and keratin; The pearlescent agent is at least one of ethylene glycol distearate and glyceryl monostearate. The other additives are at least one of antistatic agents, preservatives, and fragrances.

8. The shampoo according to claim 7, characterized in that, The matrix cleaner is fatty alcohol polyether sulfate, and the fatty alcohol polyether sulfate is sodium lauryl ether sulfate.

9. The shampoo according to claim 7, characterized in that, The auxiliary surfactant is fatty acylpropyl betaine, and the fatty acylpropyl betaine is lauroylpropyl betaine.

10. The shampoo according to claim 7, characterized in that, The antistatic agent is at least one of polyquaternium salt and guar hydroxypropyltrimethylammonium chloride; The preservative is at least one of phenoxyethanol, ethylhexylglycerin, sodium benzoate, methylparaben, and ethylparaben.

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