A rapid dispersion and dissolution system for test tablets

Abstract

This invention relates to the field of pharmaceutical testing technology, specifically to a rapid dispersion and dissolution system for testing tablets. The system provides a rapid dispersion and dissolution system for testing tablets comprising a dissolution mechanism and a circulation mechanism. In the dissolution mechanism, the tablets to be tested rub against each other under the influence of the liquid flow, causing the coating to be rapidly broken down. This allows the active ingredient to dissolve quickly into the liquid, solving the problem that existing coated tablets require manual breaking of the coating during testing or inspection, resulting in leakage of the active ingredient before it can be dissolved in the liquid for testing.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical testing technology, specifically to a rapid dispersion and dissolution system for tablets used in testing. Background Technology

[0002] In pharmaceutical production, it is necessary to select batches of tablets for testing of their active ingredients. To improve the taste when taken, some tablets are coated. Coating is a process in which sugar or other film-forming materials are applied to the outer surface of a solid drug preparation using specific equipment and a specific process. After drying, it becomes one or more layers of multifunctional protective layer with different thicknesses and elasticities that are tightly adhered to the surface. Its main components are polyvinyl alcohol, high-strength starch, etc. When testing or inspecting coated tablets, the coating needs to be manually broken to allow the active ingredients to leak out and then dissolved in a liquid for testing.

[0003] This method is suitable for small batches of samples. However, when the number of tablets to be tested in the same batch increases, the operation becomes very time-consuming and significantly reduces work efficiency. Summary of the Invention

[0004] To address the above problems, this invention provides a rapid dispersion and dissolution system for tablets used in testing.

[0005] The technical solution adopted is a rapid dispersion and dissolution system for test tablets, including a dissolution mechanism and a circulation mechanism. The dissolution mechanism contains the tablets to be tested, and the circulation mechanism is connected to the dissolution mechanism. The circulation mechanism is equipped with a dissolving agent and a heating component.

[0006] Furthermore, the dissolving mechanism includes a dissolving tank, which has a dissolving chamber inside, and the tank body is provided with a first connecting terminal and a second connecting terminal.

[0007] The first connection terminal is connected to an inlet pipe that communicates with the dissolution chamber, and the inlet pipe is also connected to the inlet tank.

[0008] The second connection terminal is connected to a second circulation tube that communicates with the dissolution chamber, and the second circulation tube is connected to the circulation mechanism.

[0009] Optionally, a first water pump is installed on the inlet pipe;

[0010] A second water pump is installed on the second circulation pipe.

[0011] Optionally, a third connection terminal is provided on the top of the dissolving tank, and a first circulation pipe communicating with the dissolving chamber is connected to the third connection terminal. The first circulation pipe is connected with the circulation mechanism.

[0012] Furthermore, the dissolving tank is equipped with a first filter screen and a second filter screen, and a solids group is placed between the first filter screen and the second filter screen.

[0013] Optionally, the connection points between the first and second connecting terminals and the dissolving tank are located between the first and second filter screens.

[0014] Optionally, the solids group includes quartz particles and tablets to be tested.

[0015] Optionally, a hook is provided on the edge of the first filter screen, and the hook is connected to the inner wall of the dissolving tank.

[0016] Furthermore, the circulation mechanism includes a circulation tank, a fourth connection terminal is provided on the body of the circulation tank, a fifth connection terminal is provided at the bottom of the circulation tank, and a pressure stabilizing port is provided at the top of the circulation tank;

[0017] The fourth connection terminal is connected to the first circulation pipe;

[0018] The fifth connection terminal is connected to the second circulation pipe.

[0019] Optionally, the circulating tank is provided with a circulating chamber, and a heating rod assembly is provided in the circulating chamber.

[0020] The beneficial effects of the present invention include at least one of the following;

[0021] 1. A rapid dispersion and dissolution system for test tablets, comprising a dissolving mechanism and a circulation mechanism, is provided, wherein the test tablets in the dissolving mechanism rub against each other under the action of the liquid flow, causing the coating to be rapidly broken down, thereby allowing the active ingredient to be rapidly dissolved in the liquid.

[0022] 2. By setting up a circulation mechanism, it can not only circulate the liquid to extract the active ingredients from the tablets, but also has a heating structure to increase the dissolution rate of the active ingredients.

[0023] 3. This solves the problem that existing coated tablets require manual breaking of the coating during testing or inspection, causing the active ingredients to leak out and then dissolve in a liquid for testing. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of a rapid dispersion and dissolution system for test tablets;

[0025] Figure 2 This is a schematic diagram of the circulating tank structure;

[0026] Figure 3 This is a schematic diagram of the dissolving tank structure;

[0027] Figure 4 This is a schematic diagram of the internal structure of the dissolving tank;

[0028] The attached diagrams are labeled as follows: 1 is the dissolving tank, 2 is the circulating tank, 3 is the first water pump, 4 is the second water pump, 5 is the inlet pipe, 6 is the first circulating pipe, 7 is the second circulating pipe, 8 is the first connecting terminal, 9 is the second connecting terminal, 10 is the third connecting terminal, 11 is the fourth connecting terminal, 12 is the fifth connecting terminal, 13 is the heating rod assembly, 14 is the circulating chamber, 15 is the dissolving chamber, 16 is the first filter screen, 17 is the hook, 18 is the second filter screen, and 19 is the solids assembly. Detailed Implementation

[0029] The following specific examples illustrate the implementation of the present invention. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and various details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention. It should be noted that, unless otherwise specified, the following embodiments and features described therein can be combined with each other.

[0030] It should be noted that the illustrations provided in the following embodiments are only schematic representations of the basic concept of the present invention. Therefore, the drawings only show the components related to the present invention and are not drawn according to the actual number, shape and size of the components in the actual implementation. In the actual implementation, the form, quantity and proportion of each component can be arbitrarily changed, and the layout of the components may also be more complex.

[0031] like Figures 1 to 4 As shown, a rapid dispersion and dissolution system for test tablets includes a dissolution mechanism and a circulation mechanism. The dissolution mechanism contains a tablet to be tested, and the circulation mechanism is connected to the dissolution mechanism. The circulation mechanism contains a dissolving agent and a heating element.

[0032] The purpose of this design is to provide a rapid dispersion and dissolution system for test tablets that includes a dissolution mechanism and a circulation mechanism. In the dissolution mechanism, the tablets to be tested will rub against each other under the action of the liquid flow, which will quickly break the coating and allow the active ingredient to dissolve rapidly into the liquid. This solves the problem that existing coated tablets require manual breaking of the coating during testing or inspection, which causes the active ingredient to leak out and then dissolve in the liquid for testing.

[0033] In practical use, the dissolving mechanism includes a dissolving tank 1, which is provided with a dissolving chamber 15, and the tank body of the dissolving tank 1 is provided with a first connecting terminal 8 and a second connecting terminal 9.

[0034] The first connecting terminal 8 is connected to an inlet pipe 5 that communicates with the dissolving chamber 15, and the inlet pipe 5 is connected to the inlet tank.

[0035] The second connection terminal 9 is connected to a second circulation pipe 7 that communicates with the dissolving chamber 15. The second circulation pipe 7 is connected to the circulation mechanism. A first water pump 3 is installed on the liquid inlet pipe 5.

[0036] A second water pump 4 is installed on the second circulation pipe 7.

[0037] The top of the dissolving tank 1 is provided with a third connection terminal 10, and a first circulation pipe 6 communicating with the dissolving chamber 15 is connected to the third connection terminal 10. The first circulation pipe 6 is connected with the circulation mechanism.

[0038] The dissolving tank 1 is equipped with a first filter screen 16 and a second filter screen 18, and a solid material group 19 is placed between the first filter screen 16 and the second filter screen 18.

[0039] The connection points between the first connecting terminal 8 and the second connecting terminal 9 and the dissolving tank 1 are located between the first filter screen 16 and the second filter screen 18.

[0040] Solids group 19 includes quartz particles and tablets to be tested.

[0041] The first filter screen 16 has a hook 17 on its edge, and is connected to the inner wall of the dissolving tank 1 through the hook 17.

[0042] The circulation mechanism includes a circulation tank 2, a fourth connection terminal 11 is provided on the body of the circulation tank 2, a fifth connection terminal 12 is provided at the bottom of the circulation tank 2, and a pressure stabilizing port is provided at the top of the circulation tank 2;

[0043] The fourth connecting terminal 11 is connected to the first circulation pipe 6;

[0044] The fifth connecting terminal 12 is connected to the second circulation pipe 7.

[0045] The circulation tank 2 is provided with a circulation chamber 14, and the circulation chamber 14 is provided with a heating rod assembly 13.

[0046] The specific working principle is as follows: when conducting the inspection, select an appropriate amount of tablet products, open the top opening of the dissolving tank, place it on the second filter screen, and then use a tool to connect the hook on the first filter screen to the inner wall of the dissolving tank.

[0047] Then, the liquid is introduced from the inlet tank into the dissolving tank by the first water pump, while the gas in the dissolving tank enters the circulation tank through the first circulation pipe and is discharged from the pressure stabilizing port.

[0048] At the same time, the liquid also enters the circulation tank, and after being heated by the heating rod assembly in the circulation tank, it re-enters the dissolving tank through the second circulation pipe. At this time, the inlet pipe is reduced or closed, and the liquid is dissolved only through the first circulation pipe, the second circulation pipe, the circulation tank and the dissolving tank. The second water pump provides the necessary power for the whole process.

[0049] In this way, by setting up a circulation mechanism, the liquid can be circulated to extract the active ingredients from the tablets, and a heating structure is set in it to increase the dissolution rate of the active ingredients.

[0050] It should be noted that, in order to improve dissolution efficiency, pure quartz particles can be added to the tablets to be tested, and the coating can be abraded by the quartz particles.

[0051] Finally, it should be noted that the above are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A rapid dispersion and dissolution system for test tablets, characterized in that, It includes a dissolving mechanism and a circulation mechanism. The dissolving mechanism contains a tablet to be tested. The circulation mechanism is connected to the dissolving mechanism and contains a dissolving agent and a heating component. The dissolving mechanism includes a dissolving tank (1) and a dissolving chamber (15) inside the dissolving tank (1). The tank body of the dissolving tank (1) is provided with a first connecting terminal (8) and a second connecting terminal (9). The first connecting terminal (8) is connected to an inlet pipe (5) that communicates with the dissolving chamber (15), and the inlet pipe (5) is connected to the inlet tank; The second connecting terminal (9) is connected to a second circulation pipe (7) that communicates with the dissolving chamber (15). The second circulation pipe (7) is connected to the circulation mechanism. The top of the dissolving tank (1) is provided with a third connecting terminal (10), and the third connecting terminal (10) is connected to a first circulation pipe (6) that communicates with the dissolving chamber (15). The first circulation pipe (6) is connected to the circulation mechanism. The dissolving tank (1) is provided with a first filter screen (16) and a second filter screen (18). A solid group (19) is placed between the first filter screen (16) and the second filter screen (18). The connection between the first connecting terminal (8) and the second connecting terminal (9) and the dissolving tank (1) is located between the first filter screen (16) and the second filter screen (18). The solid group (19) includes quartz particles and tablets to be tested.

2. The rapid dispersion and dissolution system for test tablets according to claim 1, characterized in that, A first water pump (3) is installed on the liquid inlet pipe (5); A second water pump (4) is installed on the second circulation pipe (7).

3. The rapid dispersion and dissolution system for test tablets according to claim 1, characterized in that, The first filter screen (16) is provided with a hook (17) on its edge, and is connected to the inner wall of the dissolving tank (1) through the hook (17).

4. The rapid dispersion and dissolution system for test tablets according to claim 1, characterized in that, The circulation mechanism includes a circulation tank (2), a fourth connection terminal (11) is provided on the body of the circulation tank (2), a fifth connection terminal (12) is provided at the bottom of the circulation tank (2), and a pressure stabilizing port is provided at the top of the circulation tank (2); The fourth connecting terminal (11) is connected to the first circulation pipe (6); The fifth connection terminal (12) is connected to the second circulation pipe (7).

5. The rapid dispersion and dissolution system for test tablets according to claim 4, characterized in that, The circulation tank (2) is provided with a circulation chamber (14), and a heating rod assembly (13) is provided in the circulation chamber (14).

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