An anti-aging composition and its preparation method and application
By using a compound composition of oat kernel oil, grape seed oil, avocado oil, camellia seed oil, and chamomile extract, this product addresses the issues of poor efficacy and high irritation found in existing anti-aging products, providing a gentle and effective solution for early signs of aging.
Patent Information
- Application Number
- CN202311472160.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-11-07
- Publication Date
- 2026-02-03
- Estimated Expiration
- 2043-11-07
AI Technical Summary
Most existing anti-aging products contain a single ingredient, resulting in significant short-term effects but poor long-term effects. They are also prone to causing skin irritation or oiliness, making it difficult to effectively improve the overall condition of the skin.
It uses a compound composition of oat kernel oil, grape seed oil, avocado oil, camellia seed oil and chamomile extract. By utilizing the synergistic effect of each component, it provides antioxidant, firming and anti-wrinkle effects. It is gentle, non-irritating and non-greasy.
It achieves long-term and effective anti-aging effects, is well absorbed by the skin, reduces wrinkles and vesicles, and improves skin health.
Smart Images

Figure BDA0004535502450000071 
Figure BDA0004535502450000111 
Figure BDA0004535502450000121
Abstract
Description
Technical Field
[0001] This invention belongs to the field of cosmetic technology, and specifically relates to an anti-aging composition, its preparation method, and its application. Background Technology
[0002] As we age, our skin exhibits signs of aging, including fine lines and sagging. This is due to a decrease in collagen and elastin in the skin, as well as damage from free radicals. With these early signs of aging becoming increasingly apparent, effectively combating early signs of aging has become a key research focus in the skincare industry. Currently, most anti-aging products on the market primarily target the repair of existing deep wrinkles, and most only use a single ingredient to achieve a short-term reduction in wrinkles. Skincare products that address the overall improvement of skin condition are relatively few, or their effectiveness is poor, or they contain too many ingredients, resulting in an oily feel or even significant irritation, thus limiting their effectiveness in combating early signs of aging.
[0003] Therefore, it is essential to develop a gentle, non-irritating, non-greasy product that can effectively combat early signs of aging. Summary of the Invention
[0004] The present invention aims to at least solve one of the technical problems existing in the prior art. To this end, the present invention provides an anti-aging composition, its preparation method, and its application. This anti-aging composition is mild, non-irritating, and non-greasy, and has antioxidant, firming, and anti-wrinkle effects, achieving an effective anti-aging effect.
[0005] The first aspect of the present invention provides an anti-aging composition comprising the following components: oat kernel oil, grape seed oil, avocado oil, camellia seed oil, and chrysanthemum extract.
[0006] Specifically, the effects of each component in the anti-aging composition of the present invention are as follows:
[0007] Grape seed oil contains linoleic acid, which helps maintain the skin barrier and channel function. It is easily absorbed by the skin, deeply nourishes and conditions skin cells, and has a free radical scavenging effect. It promotes appropriate cross-linking of collagen, preventing wrinkles and vesicles. Additionally, grape seed oil contains approximately 360.20 μg / g of vitamin E, which accelerates the removal of damaged and aging cells, thus delaying aging. Grape seed oil is rich in vitamins, minerals, and flavanols (proanthocyanidins), which help strengthen collagen and elastin, the connective tissue that makes up the skin and joints. Grape seed oil has a particularly high Omega-6 linoleic acid content (approximately 76%), resulting in a light texture that easily penetrates deep into the skin. Grape seed oil has conditioning and astringent properties, helping to condition the skin. When applied directly to the skin, grape seed oil is easily absorbed. Grape seed oil can also accelerate skin metabolism, speed up skin renewal, protect epidermal cells and new cells, protect skin moisture, and has a certain moisturizing effect.
[0008] Camellia seed oil is rich in monounsaturated oleic acid (approximately 80%). It won't clog pores or feel greasy due to its tannin content. As an astringent plant oil, it's more suitable for oily or problem skin than other oils rich in oleic acid. Its slightly dry and cooling nature helps prevent skin aging. Camellia seed oil has moisturizing and skin-softening effects; coupled with protective plant polyphenols, vitamins A, B, C, and E, and other antioxidants, it helps protect against UV rays, environmental damage, and free radical scavenging. It's also easily absorbed by the skin, and its plant-based squalene content nourishes and maintains healthy skin.
[0009] Avocado oil contains approximately 20% unsaturated linoleic acid and about 12% rare palmitic acid, which nourishes the skin and maintains a healthy stratum corneum. It is also rich in vitamins A, B, and E, as well as proteins and amino acids, and trace amounts of lecithin. Avocado oil promotes collagen production in the dermis (middle layer of the skin). Its phytosterols help maintain collagen and skin structure, prevent age spots and weakened cell walls, soothe inflammation, promote tissue regeneration, and maintain the skin's barrier function. Avocado oil is one of the few plant oils rich in carotenoids, providing natural protection against UV damage.
[0010] Oat kernel oil contains a balanced ratio of oleic acid and linoleic acid, approximately 40% each, which is particularly beneficial for the skin's stratum corneum. Palmitic acid, a short-chain fatty acid, can soothe and protect the outer layer of skin. Oat kernel oil is also rich in vitamin E, antioxidants, and carotenoids. It contains over 20 unique polyphenols that can fight inflammation, reduce proliferation, and relieve itching. Notably, it contains avenanthramide, a powerful antioxidant that can defend against fungal invasion. Oat kernel oil is also rich in beta-glucan, a polysaccharide, soluble fiber, and phospholipids.
[0011] Globe amaranth extract is rich in alkylamides and is considered a natural alternative to botulinum toxin. It improves dermal structure and firms the skin by stimulating fibroblast activity, and can treat dermatitis, enhance capillary resistance, eliminate free radicals, and provide antioxidant effects to alleviate aging. It also has a certain inhibitory effect on melanocytes. In summary, globe amaranth extract improves dermal structure, firms the skin, treats dermatitis, enhances capillary resistance, eliminates free radicals, and alleviates aging.
[0012] This invention utilizes a combination of several specific plant oils and extracts to create a composition that complements the lipids secreted by the skin itself, replenishing the skin's lack of oils. Simultaneously, the plant oils contain antioxidants, providing natural nutritional sunscreens to maintain the healthy function of skin cells. The components in this composition exert a synergistic effect, promoting appropriate cross-linking of collagen from multiple angles and in all aspects, preventing wrinkles and vesicles from forming on the skin, accelerating the removal of damaged and aging cells, and exhibiting antioxidant, firming, and anti-wrinkle effects, thereby effectively combating early signs of aging.
[0013] According to some embodiments of the present invention, the anti-aging composition comprises the following components: 1-20 parts of oat kernel oil, 1-50 parts of grape seed oil, 1-50 parts of avocado oil, 1-50 parts of camellia seed oil, and 0.01-2 parts of chrysanthemum extract.
[0014] According to some embodiments of the present invention, the anti-aging composition comprises, by weight parts: 5-20 parts oat kernel oil, 5-50 parts grape seed oil, 5-50 parts avocado oil, 5-50 parts camellia seed oil, and 0.5-2 parts chrysanthemum extract.
[0015] According to some embodiments of the present invention, the anti-aging composition comprises, by weight parts: 5-15 parts oat kernel oil, 5-35 parts grape seed oil, 5-35 parts avocado oil, 5-45 parts camellia seed oil, and 0.5-1.5 parts chrysanthemum extract.
[0016] A second aspect of the present invention provides a method for preparing the anti-aging composition of the present invention, comprising the following steps:
[0017] The oat kernel oil, grape seed oil, avocado oil, camellia seed oil, and chrysanthemum extract are mixed to obtain the anti-aging composition.
[0018] A third aspect of the present invention provides a cosmetic product comprising the anti-aging composition described herein.
[0019] According to some embodiments of the present invention, the composition is added to the cosmetic in an amount of 5-50 wt%.
[0020] According to some embodiments of the present invention, the composition is added to the cosmetic in an amount of 10-30 wt%.
[0021] According to some embodiments of the present invention, the dosage form of the cosmetic is selected from creams, lotions, aqueous solutions, gels, or sheet masks.
[0022] A fourth aspect of the present invention provides an essential oil comprising the anti-aging composition described herein.
[0023] Compared with the prior art, the beneficial effects of the present invention are as follows:
[0024] This invention rationally combines oat kernel oil, grape seed oil, avocado oil, camellia seed oil, and chrysanthemum extract. The components work synergistically to produce a gentle, non-irritating, and non-greasy product that is easily absorbed by the skin. It has antioxidant, firming, and anti-wrinkle effects, thus effectively combating early signs of aging. Detailed Implementation
[0025] The present invention will be further described in detail below through specific embodiments. Unless otherwise specified, the raw materials, reagents, or apparatus used in the embodiments can be obtained from conventional commercial sources or by existing technical methods. Unless otherwise specified, the experimental or testing methods are conventional methods in the art.
[0026] Example 1
[0027] An anti-aging composition comprising the following components in parts by weight:
[0028] The anti-aging composition consists of 9 parts oat kernel oil, 25 parts grape seed oil, 25 parts avocado oil, 40 parts camellia seed oil, and 1 part chrysanthemum extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0029] Example 2
[0030] An anti-aging composition comprising the following components in parts by weight:
[0031] The anti-aging composition consists of 12 parts oat kernel oil, 29 parts grape seed oil, 29 parts avocado oil, 29 parts camellia seed oil, and 1 part chrysanthemum extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0032] Example 3
[0033] An anti-aging composition comprising the following components in parts by weight:
[0034] The anti-aging composition consists of 15 parts oat kernel oil, 35 parts grape seed oil, 30 parts avocado oil, 19.2 parts camellia seed oil, and 0.8 parts chamomile extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0035] Example 4
[0036] An anti-aging composition comprising the following components in parts by weight:
[0037] The composition comprises 13 parts oat kernel oil, 22 parts grape seed oil, 35 parts avocado oil, 28.8 parts camellia seed oil, and 1.2 parts chamomile extract. This anti-aging composition is prepared by mixing the components according to the specified amounts.
[0038] Example 5
[0039] An anti-aging composition comprising the following components in parts by weight:
[0040] The anti-aging composition consists of 10 parts oat kernel oil, 30 parts grape seed oil, 43.5 parts avocado oil, 15 parts camellia seed oil, and 1.5 parts chamomile extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0041] Example 6
[0042] An anti-aging composition comprising the following components in parts by weight:
[0043] The anti-aging composition consists of 1 part oat kernel oil, 1 part grape seed oil, 50 parts avocado oil, 47 parts camellia seed oil, and 1 part chrysanthemum extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0044] Example 7
[0045] An anti-aging composition comprising the following components in parts by weight:
[0046] The anti-aging composition consists of 1 part oat kernel oil, 50 parts grape seed oil, 1 part avocado oil, 47 parts camellia seed oil, and 1 part chrysanthemum extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0047] Example 8
[0048] An anti-aging composition comprising the following components in parts by weight:
[0049] The anti-aging composition consists of 20 parts oat kernel oil, 50 parts grape seed oil, 28 parts avocado oil, 1 part camellia seed oil, and 1 part chrysanthemum extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0050] Example 9
[0051] An anti-aging composition comprising the following components in parts by weight:
[0052] The anti-aging composition consists of 1 part oat kernel oil, 46 parts grape seed oil, 50 parts avocado oil, 1 part camellia seed oil, and 2 parts chrysanthemum extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0053] Example 10
[0054] An anti-aging composition comprising the following components in parts by weight:
[0055] The composition comprises 18 parts oat kernel oil, 34 parts grape seed oil, 45 parts avocado oil, 1 part camellia seed oil, and 2 parts chrysanthemum extract. This anti-aging composition is prepared by mixing the components according to the prescribed amounts.
[0056] Example 11
[0057] An anti-aging composition comprising the following components in parts by weight:
[0058] The anti-aging composition consists of 20 parts oat kernel oil, 1 part grape seed oil, 27 parts avocado oil, 50 parts camellia seed oil, and 2 parts chrysanthemum extract. The above anti-aging composition can be prepared by mixing the components according to the prescribed amounts.
[0059] Comparative Examples 1-5
[0060] Comparative Examples 1-5 each contain only one component, as shown in Table 1.
[0061] Table 1
[0062] Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 100 parts oat kernel oil 100 parts grapeseed oil 100 parts avocado oil 100 parts camellia seed oil 100 parts of chrysanthemum extract
[0063] Comparative Examples 6-10 each lack one component, as detailed below:
[0064] Comparative Example 6
[0065] An anti-aging composition comprising the following components in parts by weight:
[0066] 27.4 parts grape seed oil, 27.4 parts avocado oil, 43.8 parts camellia seed oil, and 1.4 parts chrysanthemum extract.
[0067] The above-mentioned anti-aging composition can be prepared by mixing the components according to the formula.
[0068] Comparative Example 7
[0069] An anti-aging composition comprising the following components in parts by weight:
[0070] 11.9 parts oat kernel oil, 33.4 parts avocado oil, 53.4 parts camellia seed oil, and 1.3 parts chrysanthemum extract.
[0071] The above-mentioned anti-aging composition can be prepared by mixing the components according to the formula.
[0072] Comparative Example 8
[0073] An anti-aging composition comprising the following components in parts by weight:
[0074] Oat kernel oil 11.9 parts, grape seed oil 33.4 parts, camellia seed oil 53.4 parts, and chrysanthemum extract 1.3 parts.
[0075] The above-mentioned anti-aging composition can be prepared by mixing the components according to the formula.
[0076] Comparative Example 9
[0077] An anti-aging composition comprising the following components in parts by weight:
[0078] 15 parts oat kernel oil, 41.67 parts grape seed oil, 41.67 parts avocado oil, and 1.66 parts chamomile extract.
[0079] The above-mentioned anti-aging composition can be prepared by mixing the components according to the formula.
[0080] Comparative Example 10
[0081] An anti-aging composition comprising the following components in parts by weight:
[0082] Oat kernel oil 9.1 parts, grape seed oil 25.25 parts, avocado oil 25.25 parts, and camellia seed oil 40.4 parts.
[0083] The above-mentioned anti-aging composition can be prepared by mixing the components according to the formula.
[0084] Comparative Example 11
[0085] The difference between Comparative Example 11 and Example 1 is that grape seed oil was replaced with olive fruit oil in Comparative Example 11, while the other components, amounts added, and preparation methods were the same as in Example 1.
[0086] Comparative Example 12
[0087] The difference between Comparative Example 12 and Example 1 is that camellia seed oil was replaced with meadowfoam seed oil in Comparative Example 12, while the other components, amounts added, and preparation methods were the same as in Example 1.
[0088] Comparative Example 13
[0089] The difference between Comparative Example 13 and Example 1 is that oat kernel oil was replaced with wheat germ oil in Comparative Example 13, while the other components, amounts added, and preparation methods were the same as in Example 1.
[0090] Comparative Example 14
[0091] The difference between Comparative Example 14 and Example 1 is that avocado oil was replaced with borage seed oil in Comparative Example 14, while the other components, amounts added, and preparation methods were the same as in Example 1.
[0092] Comparative Example 15
[0093] The difference between Comparative Example 15 and Example 1 is that the chrysanthemum extract in Comparative Example 15 was replaced with rosehip oil, while the other components, amounts added, and preparation methods were the same as in Example 1.
[0094] Application Example 1
[0095] An essential oil containing the anti-aging composition of the present invention has the formulation shown in Table 2.
[0096] Table 2
[0097]
[0098] The above-mentioned essential oils can be prepared by mixing the components of group A, group B, group C and group D at room temperature according to the proportions in Table 2, and stirring until homogeneous.
[0099] Application Example 2
[0100] The difference from Application Example 1 is that the mass percentage of the anti-aging composition in Example 1 is 5%, the mass percentage of isononyl isononanoate should be increased accordingly, but still increased to 100%, and the percentage content of the remaining components remains unchanged.
[0101] Application Example 3
[0102] The difference from Application Example 1 is that the mass percentage of the anti-aging composition in Example 1 is 50%, the mass percentage of isononyl isononanoate should be reduced accordingly, but still increased to 100%, and the percentage content of the remaining components remains unchanged.
[0103] Application Example 4
[0104] The difference from Application Example 1 is that the mass percentage of the anti-aging composition in Example 1 is 4%, the mass percentage of isononyl isononanoate should be increased accordingly, but still increased to 100%, and the percentage content of the remaining components remains unchanged.
[0105] Application Example 5
[0106] The difference from Application Example 1 is that the mass percentage of the anti-aging composition in Example 1 is 55%, the mass percentage of isononyl isononanoate should be reduced accordingly, but still increased to 100%, and the percentage content of the remaining components remains unchanged.
[0107] Application Example 6
[0108] The difference between Application Example 6 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 2 in Application Example 6, while the other components, amounts added, and preparation methods are the same as in Application Example 1.
[0109] Application Example 7
[0110] The difference between Application Example 7 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 3 in Application Example 7, while the other components, addition amounts and preparation methods are the same as in Application Example 1.
[0111] Application Example 8
[0112] The difference between Application Example 8 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 4 in Application Example 8, while the other components, amounts added, and preparation methods are the same as in Application Example 1.
[0113] Application Example 9
[0114] The difference between Application Example 9 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 5 in Application Example 9, while the other components, amounts added, and preparation methods are the same as in Application Example 1.
[0115] Application Example 10
[0116] The difference between Application Example 10 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 6 in Application Example 10, while the other components, amounts added and preparation methods are the same as in Application Example 1.
[0117] Application Example 11
[0118] The difference between Application Example 11 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 7 in Application Example 11, while the other components, amounts added and preparation methods are the same as in Application Example 1.
[0119] Application Example 12
[0120] The difference between Application Example 12 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 8 in Application Example 12, while the other components, amounts added and preparation methods are the same as in Application Example 1.
[0121] Application Example 13
[0122] The difference between Application Example 13 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 9 in Application Example 13, while the other components, amounts added and preparation methods are the same as in Application Example 1.
[0123] Application Example 14
[0124] The difference between Application Example 14 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 10 in Application Example 14, while the other components, amounts added and preparation methods are the same as in Application Example 1.
[0125] Application Example 15
[0126] The difference between Application Example 15 and Application Example 1 is that the anti-aging composition of Example 1 is replaced with the anti-aging composition of Example 11 in Application Example 15, while the other components, amounts added and preparation methods are the same as in Application Example 1.
[0127] Application Comparative Example 1
[0128] The difference from Application Example 1 is that, without the anti-aging composition of Example 1, the mass percentage of isononyl isononanoate should be increased accordingly, but still increased to 100%, while the percentage content of the other components remains unchanged.
[0129] Application Comparative Example 2
[0130] The difference between Comparative Example 2 and Comparative Example 1 is that Comparative Example 2 replaces the anti-aging composition of Example 1 with the anti-aging composition of Comparative Example 1, while the other components, amounts added, and preparation methods are the same as in Comparative Example 1.
[0131] Application Comparative Example 3
[0132] The difference between Comparative Example 3 and Comparative Example 1 is that the anti-aging composition of Comparative Example 3 is replaced with the anti-aging composition of Comparative Example 2, while the other components, amounts added, and preparation methods are the same as those in Comparative Example 1.
[0133] Application Comparative Example 4
[0134] The difference between Comparative Example 4 and Comparative Example 1 is that the anti-aging composition of Comparative Example 4 is replaced with the anti-aging composition of Comparative Example 3, while the other components, amounts added, and preparation methods are the same as those in Comparative Example 1.
[0135] Application Comparative Example 5
[0136] The difference between Comparative Example 5 and Comparative Example 1 is that Comparative Example 5 replaces the anti-aging composition of Example 1 with the anti-aging composition of Comparative Example 4, while the other components, amounts added, and preparation methods are the same as in Comparative Example 1.
[0137] Application Comparative Example 6
[0138] The difference between Comparative Example 6 and Comparative Example 1 is that Comparative Example 6 replaces the anti-aging composition of Example 1 with the anti-aging composition of Comparative Example 5, while the other components, amounts added, and preparation methods are the same as in Comparative Example 1.
[0139] Application Comparative Example 7
[0140] The difference between Comparative Example 7 and Comparative Example 1 is that Comparative Example 7 replaces the anti-aging composition of Example 1 with the anti-aging composition of Comparative Example 6, while the other components, amounts added, and preparation methods are the same as in Comparative Example 1.
[0141] Application Comparative Example 8
[0142] The difference between Comparative Example 8 and Comparative Example 1 is that Comparative Example 8 replaces the anti-aging composition of Example 1 with the anti-aging composition of Comparative Example 7, while the other components, amounts added, and preparation methods are the same as in Comparative Example 1.
[0143] Application Comparison Example 9
[0144] The difference between Comparative Example 9 and Comparative Example 1 is that Comparative Example 9 replaces the anti-aging composition of Example 1 with the anti-aging composition of Comparative Example 8, while the other components, amounts added, and preparation methods are the same as in Comparative Example 1.
[0145] Application Comparison Example 10
[0146] The difference between Comparative Example 10 and Comparative Example 1 is that Comparative Example 10 replaces the anti-aging composition of Example 1 with the anti-aging composition of Comparative Example 9, while the other components, amounts added, and preparation methods are the same as in Comparative Example 1.
[0147] Application Comparative Example 11
[0148] The difference between Comparative Example 11 and Comparative Example 1 is that the anti-aging composition of Comparative Example 11 is replaced with the anti-aging composition of Comparative Example 10, while the other components, amounts added, and preparation methods are the same as those in Comparative Example 1.
[0149] Application Comparative Example 12
[0150] The difference between Comparative Example 12 and Comparative Example 1 is that the anti-aging composition of Comparative Example 12 is replaced with the anti-aging composition of Comparative Example 11, while the other components, amounts added, and preparation methods are the same as those in Comparative Example 1.
[0151] Application Comparative Example 13
[0152] The difference between Comparative Example 13 and Comparative Example 1 is that the anti-aging composition of Comparative Example 13 is replaced with the anti-aging composition of Comparative Example 12, while the other components, amounts added, and preparation methods are the same as those in Comparative Example 1.
[0153] Application Comparative Example 14
[0154] The difference between Comparative Example 14 and Comparative Example 1 is that the anti-aging composition of Comparative Example 14 is replaced with the anti-aging composition of Comparative Example 13, while the other components, amounts added, and preparation methods are the same as those in Comparative Example 1.
[0155] Application Comparative Example 15
[0156] The difference between Comparative Example 15 and Comparative Example 1 is that the anti-aging composition of Comparative Example 15 is replaced with the anti-aging composition of Comparative Example 14, while the other components, amounts added, and preparation methods are the same as those in Comparative Example 1.
[0157] Application Comparative Example 16
[0158] The difference between Comparative Example 16 and Comparative Example 1 is that the anti-aging composition of Comparative Example 16 is replaced with the anti-aging composition of Comparative Example 15, while the other components, amounts added, and preparation methods are the same as those in Comparative Example 1.
[0159] Test Example 1 Patch Test
[0160] Test substances: essential oils from Examples 1-15 and Comparative Examples 1-16.
[0161] Subjects: A total of 50 participants, including 25 males and 25 females, aged 20-40 years, who met the inclusion criteria for subject volunteers.
[0162] Test Method: Using a syringe, dispense 0.03 mL of sample into the drug chamber of the test strip. Immediately apply the test strip containing the sample longitudinally to the normal skin of the left forearm, starting from the bottom. Simultaneously, gently press each drug chamber to expel air and ensure even distribution of the test sample. Mark the test sites for observation. The blank control group consists of subjects who do not use the product.
[0163] Results Analysis: After 24 hours, the adhesive tape was removed, and skin reactions were observed at 30 minutes, 24 hours, and 48 hours. The results were recorded and analyzed according to the CTFA guidelines. The severity of adverse skin reactions is shown in Table 3, and the test results are shown in Table 4.
[0164] Table 3
[0165] grade symbol Identification Standards 0 - Negative reaction: no irritation, no erythema 1 ± Suspected reaction: Mild erythema 2 + Weak positive reaction: erythema 3 ++ Strong positive reaction: erythema, papules, vesicles 4 +++ Extremely strong positive reaction: severe edema, large bullae
[0166] Table 4
[0167]
[0168]
[0169]
[0170] As can be seen from the data in Table 4, among the 50 subjects, no adverse skin reactions were observed with the essential oils prepared using Application Examples 1-15, Application Comparative Examples 1, Application Comparative Examples 2, Application Comparative Examples 3, Application Comparative Examples 4, Application Comparative Examples 5, Application Comparative Examples 7, Application Comparative Examples 8, Application Comparative Examples 9, Application Comparative Examples 11, Application Comparative Examples 12, Application Comparative Examples 13, Application Comparative Examples 14, Application Comparative Examples 15, and Application Comparative Examples 16; while one case of Grade 1 adverse reaction was observed with the essential oils prepared using Application Comparative Examples 6 and Application Comparative Examples 10, indicating that the essential oils containing the anti-aging composition of the present invention are gentler, safer, and less irritating.
[0171] Experimental Example 2: Determination of Superoxide Anion Radical Scavenging Capacity
[0172] Test samples: Anti-aging compositions of Examples 1-11 and Comparative Examples 1-15.
[0173] The specific measurement method is as follows:
[0174] Take 4.5 mL of 0.05 mol / L Tris-HCl buffer (pH 8.2) and preheat it in a 25°C water bath for 20 min. Add 1 mL of the test sample, followed by 0.4 mL of 25 mmol / L pyrogallol solution (preheated in a 25°C water bath for 20 min). Mix well and react in a 25°C water bath for 5 min. Terminate the reaction by adding 1.0 mL of 8 mol / L hydrochloric acid. Measure the absorbance at 299 nm using the Tris-HCl buffer as a reference.
[0175] Blank control experiment: Replace the test sample with only 1 mL of ethanol, and keep other steps unchanged. Calculate the clearance rate (D) according to formula (1).
[0176] D(%)=[1-(A2 / A1)]×100% Equation (1);
[0177] 1) In the formula, A1 is the absorbance value of the blank control; A2 is the absorbance value of the test sample after testing.
[0178] The test results are shown in Table 5.
[0179] Table 5
[0180]
[0181]
[0182] As shown in Table 5, the anti-aging compositions of Examples 1-11 all have good free radical scavenging ability. However, the effects of Examples 1-11 cannot be achieved by using only a single component (Comparative Examples 1-5), or a composition lacking any component (Comparative Examples 6-10), or by replacing the components in Example 1 with other components with similar effects (Comparative Examples 11-15).
[0183] Experiment 3: Body Firming Efficacy Test
[0184] Test substances: essential oils from Examples 1-15 and Comparative Examples 1-16.
[0185] Experimental Methods: 310 participants (aged 30-45) with wrinkles around the eyes were selected as volunteers for the firming and anti-wrinkle efficacy test (10 volunteers used the same sample). Participants applied the product to the skin around their eyes twice daily, morning and evening. On day 0, day 7 (D7), and day 14 (D14), under conditions of 21±1℃ and 50±10% humidity, facial elasticity (R²) was measured after cleansing the face and waiting 20 minutes. The overall effect of the product on skin firming was evaluated.
[0186] Testing instrument: MPA580 skin elasticity tester (manufactured by CK GmbH, Germany).
[0187] The firming effect of a product is evaluated by measuring the skin elasticity R² value, which is the rate of change in skin elasticity after product use compared to before use. A positive value indicates an increase in the ratio of maximum skin stretch displacement, indicating better skin elasticity, while a negative value indicates a decrease in the ratio of maximum skin stretch displacement, indicating poorer skin elasticity.
[0188] Result determination: If the change in the instrument test parameter (elasticity R2 value) at any viewing point after product use is improved compared to before use, the product is considered to have a firming effect; otherwise, the product is considered not to have a firming effect. The test results are shown in Table 6.
[0189] Table 6
[0190]
[0191]
[0192]
[0193] As shown in Table 6, the essential oils in Application Examples 1-15 all have firming effects. However, the content of the anti-aging composition in Application Example 4 is too low (less than 5%), which reduces the effect. The content of the anti-aging composition in Application Example 5 is too high (greater than 50%), resulting in a lower R2 change rate. It also tends to make the cosmetics too oily, resulting in a poor user experience, difficulty in absorbing nutrients, and potential clogging of pores, thus affecting the cosmetics' effectiveness. Using only a single component (Application Examples 2-6), or a composition lacking any one component (Application Examples 7-11), or replacing the components in the anti-aging composition of the present invention with other components with similar effects (Application Examples 12-16) cannot achieve the effects of Application Examples 1-15.
[0194] Experiment 4: Anti-wrinkle efficacy test on human body
[0195] Test substances: essential oils from Examples 1-15 and Comparative Examples 1-16.
[0196] Test Method: 310 participants (aged 30-45) with wrinkles around the eyes were selected as volunteers for the firming and anti-wrinkle efficacy test (10 volunteers used the same sample) (same as volunteers in Experiment 3). Participants applied the product to the eye area twice a day, morning and evening. On day 0, day 7 (D7), and day 14 (D14), under conditions of 21±1℃ and 50±10% humidity, participants cleansed their faces and waited 20 minutes before taking photos of their faces using a VISIA 7. The number of wrinkles around the eyes, the total area of wrinkles, the average length of wrinkles, and the percentage of wrinkle area were measured to evaluate the anti-wrinkle efficacy of the product.
[0197] Average wrinkle length change rate: This refers to the rate of change in the average length of wrinkles around the eyes after product use compared to before use. A positive value indicates an increase in the average length of wrinkles around the eyes, meaning the wrinkles are longer; a negative value indicates a decrease in the average length of wrinkles around the eyes, meaning the wrinkles are shorter.
[0198] Wrinkle count change rate: This refers to the rate of change in the number of wrinkles around the eyes after product use compared to before use. A positive value indicates an increase in the number of wrinkles around the eyes, meaning there are more wrinkles around the eyes; a negative value indicates a decrease in the number of wrinkles around the eyes, meaning there are fewer wrinkles around the eyes.
[0199] Change rate of total wrinkle area: This refers to the rate of change in the total area of wrinkles around the eyes after product use compared to before use. A positive value indicates an increase in the total area of wrinkles around the eyes, meaning more wrinkles are present; a negative value indicates a decrease in the total area of wrinkles around the eyes, meaning fewer wrinkles are present.
[0200] Change rate of wrinkle area percentage: This refers to the rate of change in the percentage of wrinkles around the eyes after product use compared to before use. A positive value indicates an increase in the percentage of wrinkles around the eyes, meaning more wrinkles; a negative value indicates a decrease in the percentage of wrinkles around the eyes, meaning fewer wrinkles.
[0201] The test results are shown in Table 7.
[0202] Table 7
[0203]
[0204]
[0205]
[0206]
[0207]
[0208]
[0209]
[0210]
[0211]
[0212]
[0213] As shown in Table 7, the essential oils in Application Examples 1-15 all have anti-wrinkle capabilities. However, the content of the anti-aging composition in Application Example 4 is too low (less than 5%), resulting in reduced effectiveness. The content of the anti-aging composition in Application Example 5 is too high (greater than 50%). Although the number of wrinkles around the eyes, total wrinkle area, average wrinkle length, and wrinkle area percentage decreased in the first 7 days, these values actually increased after 14 days compared to the 7-day data. This fails to achieve the desired effect and can easily lead to excessively oily cosmetics, poor user experience, and difficulty in absorbing nutrients. It may also clog pores and affect the effectiveness of the cosmetics. Using only a single component (Application Examples 2-6), or a composition lacking any component (Application Examples 7-11), or replacing the components in the anti-aging composition of this invention with other components of similar efficacy (Application Examples 12-16) cannot achieve the effects of Application Examples 1-15.
[0214] Based on the above experimental results, by adjusting the ratio of each component in the anti-aging composition of the present invention and adjusting the mass percentage of the anti-aging composition of the present invention in cosmetics, a more superior anti-aging effect can be obtained.
[0215] The preferred embodiments of the present invention have been described in detail above, but the present invention is not limited to the embodiments described. Those skilled in the art can make various equivalent modifications or substitutions without departing from the spirit of the present invention, and these equivalent modifications or substitutions are all included within the scope defined by the claims of this application.
Claims
1. An anti-aging composition, characterized in that, The anti-aging composition comprises, by weight, 1-20 parts oat kernel oil, 1-50 parts grape seed oil, 1-50 parts avocado oil, 1-50 parts camellia seed oil, and 0.01-2 parts chrysanthemum extract.
2. The anti-aging composition according to claim 1, characterized in that, The anti-aging composition comprises, by weight, 5-20 parts oat kernel oil, 5-50 parts grape seed oil, 5-50 parts avocado oil, 5-50 parts camellia seed oil, and 0.5-2 parts chrysanthemum extract.
3. The anti-aging composition according to claim 2, characterized in that, The anti-aging composition comprises, by weight, 5-15 parts oat kernel oil, 5-35 parts grape seed oil, 5-35 parts avocado oil, 5-45 parts camellia seed oil, and 0.5-1.5 parts chrysanthemum extract.
4. A method for preparing the anti-aging composition according to any one of claims 1 to 3, characterized in that, Includes the following steps: The oat kernel oil, grape seed oil, avocado oil, camellia seed oil, and chrysanthemum extract are mixed to obtain the anti-aging composition.
5. A cosmetic product, characterized in that, Includes the anti-aging composition according to any one of claims 1 to 3.
6. The cosmetic product according to claim 5, characterized in that, The amount of the anti-aging composition added is 5-50 wt%.
7. The cosmetic product according to claim 6, characterized in that, The amount of the anti-aging composition added is 10-30 wt%.
8. The cosmetic product according to claim 5, characterized in that, The dosage form of the cosmetic is selected from cream, lotion, liquid, gel or sheet mask.
9. An essential oil, characterized in that, Includes the anti-aging composition according to any one of claims 1 to 3.