Fully automatic reaction waiting mechanism and use method of immunochromatographic test card

Abstract

The present invention provides an immunochromatographic detection card fully automatic reaction waiting mechanism and a method of use, comprising a detection card to be fed in, a card feeding and pushing motor, a photoelectric detection module, a turntable, a card slot, a card output notch, a card feeding and lifting motor, and a sample adding mechanism. The detection card to be fed in is located on one side of the sample adding mechanism, and the card feeding mechanism is placed at one end of the sample adding mechanism. The card feeding mechanism includes a card feeding and lifting motor and a card feeding and pushing motor. The detection card to be fed in after the sample is added is adjusted to a suitable height by the card feeding and lifting motor, and then the detection card to be fed in is fed into the card slot of the turntable by the card feeding and pushing motor. The present invention is compatible with the detection of each waiting time and the number of cards fed, and can achieve continuous detection.

Description

Technical Field

[0001] The invention belongs to the technical field of detection equipment, and in particular relates to a fully automatic reaction waiting mechanism of an immunochromatographic detection card and a use method thereof. Background Art

[0002] Immunochromatography is a widely used detection technology that is simple to use and quick to detect. From the operation process, when the sample solution is dripped into the test card, according to the principle of immunochromatography, it takes 5-15 minutes for the sample to completely soak the test card and react. Finally, the instrument reads the reaction value signal.

[0003] Technical solution of prior art 1

[0004] A. In the existing testing process, after the sample is dripped in, it is usually sent to the instrument after waiting for the reaction to complete outside the instrument. Or it can be directly inserted into the instrument and the instrument will count down. After the time is reached, the test will be carried out.

[0005] B. Due to the sample waiting time, the existing fully automatic immunoassay detectors usually support around 20 disposable test cards.

[0006] Disadvantages of existing technology

[0007] A. In fact, the detection time and sample addition time are very short. The overall time is composed of sample addition time, waiting time and detection time. The detection time is usually 5-15 minutes, and the sample addition time is usually 3 seconds. Therefore, the main contradiction in the entire detection process is the 5-15 minutes of waiting time for chromatography. This waiting time after sample addition is the bottleneck of the entire process, so the fluency of the overall immune chromatography automated detection is very limited, and it is impossible to achieve unlimited continuous detection in batches.

[0008] B. Whether the waiting time of chromatography is accurate will affect the consistency of the test results. The waiting time of manual operation fluctuates greatly, and it is easy to confuse when there are too many test cards. Summary of the invention

[0009] The purpose of the present invention is to solve the defects of the above-mentioned prior art and provide an automatic reaction waiting mechanism for immunochromatographic detection cards and a method for using the mechanism, which is a turntable-type sample addition and card storage mechanism, a sampling stack-type first-in-first-out mode for card feeding, and supports unlimited continuous and accurate card feeding. It can solve the problem of delayed card feeding after sample addition in the existing immunochromatographic detection card.

[0010] The present invention adopts the following technical solution:

[0011] The fully automatic reaction waiting mechanism of the epidemic chromatography detection card includes a detection card to be sent in, a card pushing motor, a photoelectric detection module, a turntable, a card slot, a card output notch, a card shell lifting platform, a sample adding mechanism, a rotating motor, a card output motor, a card output detection port, a feeding lifting platform motor, and a card shell lifting motor.

[0012] The test card to be fed is placed on the loading table. The card feeding mechanism is placed at one end of the loading mechanism, and the card feeding mechanism includes a card pushing motor, a card feeding lifting motor, a feeding lifting platform motor, and a card case lifting motor. The test card to be fed after the sample is fed is fed into the lifting platform by the feeding lifting platform motor, and the lifting platform is adjusted to a suitable height by the card case lifting motor, and the test card to be fed is fed into the card feeding platform, and the card feeding platform is adjusted to a suitable height by the card feeding lifting motor, and finally the test card to be fed is fed into the card slot of the turntable by the card pushing motor.

[0013] The turntable is located at the corresponding position of the card feeding mechanism. The turntable has a card slot. A fixed disc with a card outlet notch is installed at the lower part of the turntable. The center of the disc coincides with the center of the turntable. When the turntable rotates to stop, there is always a card slot on the turntable corresponding to the card outlet notch on the disc.

[0014] An open ring is fixedly installed on the disc. The height and width of the card slot match the size of the gap of the open ring. A photoelectric detection module is installed on the top of each card slot. The photoelectric detection module is connected to the controller. The controller controls the rotation of the rotary motor, controls the number of detection cards to be fed into the card slot, and ensures that any card slot is always aligned with the card feeding mechanism when the turntable stops.

[0015] Furthermore, a rotating motor is installed at the bottom of the turntable, and the turntable has radial slots.

[0016] Furthermore, the length and width of the test card to be fed in match the length and width of the card outlet gap to ensure that the test card to be fed in can fall into the card outlet slot of the card outlet mechanism from the card outlet gap. The card outlet mechanism includes a card outlet slot, a card outlet motor, and a card outlet detection port. The lower part of the card outlet gap is a card outlet slot installed on the base, and a card outlet motor for pushing the test card to be fed in to slide out is installed on one side of the card outlet slot, and a card outlet detection port with a detector installed on the other side.

[0017] Furthermore, the length and width of the card slot are consistent with the length and width of the test card, and one card slot of the turntable can stack multiple test cards to be fed in.

[0018] Furthermore, the controller adjusts the card feeding time of the card feeding mechanism, the rotation direction of the turntable, and the rotation speed of the rotating motor to adjust the waiting time to be equal to the detection time.

[0019] Further, the turntable cover is closed on the open ring.

[0020] Furthermore, the turntable has 8 card slots.

[0021] The method for using the fully automatic reaction waiting mechanism of the immunochromatographic test card comprises the following steps:

[0022] Step 1. Send the test card to be sent into the sample adding mechanism for sample addition, and the controller starts timing;

[0023] Step 2. Send the added test card into the card feeding mechanism, and adjust the card housing lifting motor and card pushing motor of the card feeding mechanism to send the test card to be fed into the card slot;

[0024] Step 3. The controller controls the number of test cards to be fed into the card slot, the rotation direction of the rotating motor, and the rotation speed of the rotating motor according to the designed test time;

[0025] Step 4. The rotating motor stops, and the card to be sent into the card slot falls into the card outlet gap of the lower disc by gravity, and then is sent into the card outlet inspection port by the card outlet mechanism. At this time, the inspection time is equal to the waiting time.

[0026] Beneficial effects of the present invention:

[0027] (1) Eliminate the impact of test waiting time on the entire test continuity

[0028] The turntable card has large capacity, small size and convenient operation. Through the time of card release, the fully automatic test card waiting time transition is realized at the lowest cost. It can realize unlimited number of continuous card supply, which can perfectly solve the problem of waiting time card of immunochromatographic test card.

[0029] (2). Compatible with cards with different waiting times

[0030] By switching between the forward and reverse modes of the turntable, it can be compatible with cards with different waiting times, and the system has good compatibility. For example, if the waiting time of the card sent in the front is longer, and the waiting time of the card sent in the back is shorter, the turntable can send out the card put in the back first through the reverse mode. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 It is a schematic diagram of the top view of the structure of the present invention;

[0032] Figure 2 It is a schematic diagram of the top view of the structure of the present invention without the turntable cover;

[0033] Figure 3 It is a side view of the present invention without the turntable cover;

[0034] Figure 4 The overall side view of the present invention Figure Ⅰ ;

[0035] Figure 5 The overall side view of the present invention Figure II ;

[0036] Figure 6 The overall side view of the present invention Figure III ;

[0037] Figure 7 The overall side view of the present invention Figure IV .

[0038] In the figure: 1-to-be-fed inspection card, 2-card pushing motor, 3-photoelectric detection module, 4-turntable, 5-card slot, 6-card outlet notch, 7-card lifting platform, 8-sample loading mechanism, 9-rotating motor, 10-card outlet motor, 11-card outlet inspection port, 12-input lifting platform motor, 13-card lifting motor. DETAILED DESCRIPTION

[0039] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention is described clearly and completely below. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0040] like Figure 1-7 As shown, the fully automatic reaction waiting mechanism of the immunochromatographic detection card of the present invention includes a detection card to be fed in 1, a card pushing motor 2, a photoelectric detection module 3, a turntable 4, a card slot 5, a card output notch 6, a card shell lifting platform 7, a sample adding mechanism 8, a rotating motor 9, a card output motor 10, a card output detection port 11, a feeding lifting platform motor 12, and a card shell lifting motor 13.

[0041] The test card to be fed is placed on the sample loading table. The card feeding mechanism is placed at one end of the sample loading mechanism, and the card feeding mechanism includes a card pushing motor, a card feeding lifting motor, a feeding lifting platform motor, and a card case lifting motor. The test card to be fed after the sample is fed is fed into the lifting platform by the feeding lifting platform motor, and the lifting platform is adjusted to a suitable height by the card case lifting motor, and the test card to be fed is fed into the card feeding platform, and the card feeding platform is adjusted to a suitable height by the card feeding lifting motor, and finally the test card to be fed is fed into the card slot 5 of the turntable 4 by the card pushing motor.

[0042] The turntable 4 is located at the corresponding position of the card feeding mechanism. The turntable 4 has a card slot 5. A fixed disc with a card outlet notch is installed at the lower part of the turntable 4. The center of the disc coincides with the center of the turntable 4. When the turntable 4 rotates to stop, there is always a card slot 5 on the turntable 4 corresponding to the card outlet notch on the disc.

[0043] A rotating motor is installed at the bottom of the turntable 4. The turntable 4 has radial card slots 5, and an open ring is fixedly installed on the disk. The height and width of the card slots 5 match the size of the gap of the open ring. A photoelectric detection module is installed on the top of each card slot 5. The photoelectric detection module is connected to the controller. The controller controls the rotation of the rotating motor, controls the number of detection cards to be fed into the card slots 5, and ensures that any card slot 5 is always aligned with the card feeding mechanism when the turntable 4 stops.

[0044] The length and width of the test card 1 to be fed in match the length and width of the card-out notch 6 to ensure that the test card 1 to be fed in can fall from the card-out notch into the card-out slot of the card-out mechanism. The card-out mechanism includes a card-out slot, a card-out motor 10, and a card-out detection port 11. The lower part of the card-out notch 6 is a card-out slot installed on the base. A card-out motor 10 for pushing the test card to be fed in to slide out is installed on one side of the card-out slot, and a card-out detection port 11 with a detector is installed on the other side. The length and width of the card slot 5 are consistent with the length and width of the test card, and one card slot 5 of the turntable 4 can stack multiple test cards 1 to be fed in.

[0045] Furthermore, the turntable 4 is covered on the open ring.

[0046] The turntable 4 has 8 card slots in total. The controller adjusts the card feeding time of the card feeding mechanism, the rotation direction of the turntable 4, and the rotation speed of the rotating motor 9 to adjust the waiting time to be equal to the detection time.

[0047] Working process of the present invention:

[0048] 1. Rotary disk reaction waiting mechanism

[0049] When the test paper of the test card 1 to be sent in is loaded with the sample, the controller starts timing, and the card pushing motor 2 pushes the test card 1 to be sent in from bottom to top into the card slot 5 of the turntable 4. The card slot 5 of the turntable 4 is composed of 8 slots in total, and there is a photoelectric detection module 3 on the top of each slot to detect the number of test cards. When the test card 1 is full, the turntable 4 will automatically rotate to the next card slot 5. The card slot 5 and the external card feeding mechanism have a photoelectric positioning design to ensure that each rotation can be accurately aligned without mechanical alignment errors. According to this process, the slots in the turntable 4 will rotate one by one. When it rotates to the card outlet gap 6 of the disc, the test card 1 to be sent in that is first placed in the turntable 4 will fall into the card outlet gap 6 under the action of gravity. Falling into the card outlet slot, it is then sent to the card outlet detection port 11 by the card outlet motor 10 of the card outlet mechanism, and then the card outlet continues to be discharged according to the first-in-first-out process.

[0050] The whole process cleverly utilizes the characteristics of the turntable 4, which has a large card capacity, a small size, and is easy to operate. The card is temporarily cached in different card slots 5 in the turntable 4, and the slow rotation method realizes the fully automatic transition of the waiting time of the test card. Since new cards are continuously added while the cards are being output, an unlimited number of cyclic continuous card supply can be achieved. In general, except for the initial waiting time of the first batch of cards, the test will continue without waiting as long as the machine is not turned off. It can perfectly solve the problem of waiting time card points of immunochromatographic test cards.

[0051] 2. Multifunctional control mode

[0052] In the actual use of immunoassay test cards, different test types may have different waiting times, and there may also be interruptions in the card supply, all of which may affect the smoothness and continuity of the test.

[0053] Therefore, the structure of the turntable 4 can first stop, rotate clockwise, counterclockwise, high speed, and low speed. In the process of feeding the card, if the reaction time is fast, the card slot 5 can be rotated when it is not full. This rotation can be clockwise or counterclockwise. If only one card is placed, the counterclockwise rotation is the fastest card output mode, which is equivalent to no buffer. If fine-tuning the time is required, the dynamic and flexible adjustment of the card output time point can be easily completed through the three variable controls of card loading time + rotation speed + rotation mode. It can meet all the waiting requirements for detection time.

[0054] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. The fully automatic reaction waiting mechanism of the immunochromatographic test card is characterized by: It includes the test card to be fed in, the card pushing motor, the turntable, the card slot, the card shell lifting platform, the sample adding mechanism, the rotating motor, the feeding lifting platform motor, and the card shell lifting motor; The test card to be fed is placed on the sample loading table, and the card feeding mechanism is placed at one end of the sample loading mechanism. The card feeding mechanism includes a card pushing motor, a card feeding lifting motor, a feeding lifting platform motor, and a jamming lifting motor. The test card to be fed after the sample is fed is fed into the lifting platform by the feeding lifting platform motor, and the lifting platform is adjusted to a suitable height by the jamming lifting motor, and the test card to be fed is fed into the card feeding platform. The card feeding platform is adjusted to a suitable height by the card feeding lifting motor, and finally the test card to be fed is fed into the card slot of the turntable by the card pushing motor; the turntable is located at the corresponding position of the card feeding mechanism, and there is a card slot on the turntable. A fixed disc with a card output notch is installed at the lower part of the turntable, and the center of the disc coincides with the center of the turntable. When the turntable rotates to stop, there is always a card slot on the turntable corresponding to the card output notch on the disc; An open ring is fixedly installed on the disc, and the height and width of the card slot match the size of the gap of the open ring. A photoelectric detection module is installed on the top of each card slot. The photoelectric detection module is connected to the controller. The controller controls the rotation of the rotary motor to control the number of detection cards to be fed into the card slot and ensure that any card slot is always aligned with the card feeding mechanism when the turntable stops. The controller adjusts the card feeding time of the card feeding mechanism, the rotation direction of the turntable, and the rotation speed of the rotating motor to adjust the waiting time to be equal to the detection time.

2. The fully automatic reaction waiting mechanism of the immunochromatographic detection card according to claim 1, characterized in that: A rotating motor is installed at the bottom of the turntable, and the turntable has radial slots.

3. The fully automatic reaction waiting mechanism of the immunochromatographic detection card according to claim 1, characterized in that: The length and width of the test card to be fed in match the length and width of the card output gap to ensure that the test card to be fed in falls from the card output gap into the card output slot of the card output mechanism. The card output mechanism includes a card output slot, a card output motor, and a card output detection port. The lower part of the card output gap is a card output slot installed on the base, and a card output motor for pushing the test card to be fed in to slide out is installed on one side of the card output slot, and the other side is a card output detection port equipped with a detector.

4. The fully automatic reaction waiting mechanism of the immunochromatographic detection card according to claim 1, characterized in that: The length and width of the card slot are consistent with the length and width of the test card, and one card slot of the turntable can stack multiple test cards to be fed in.

5. The fully automatic reaction waiting mechanism of the immunochromatographic detection card according to claim 1, characterized in that: The turntable cover closes over the split ring.

6. The fully automatic reaction waiting mechanism of the immunochromatographic detection card according to claim 1, characterized in that: The turntable has 8 card slots.

7. A method for using the fully automatic reaction waiting mechanism of the immunochromatographic test card according to claim 1, characterized in that: Includes steps: Step 1. Send the test card to be sent into the sample adding mechanism for sample addition, and the controller starts timing; Step 2. Send the added test card into the card feeding mechanism, and adjust the card housing lifting motor and card pushing motor of the card feeding mechanism to send the test card to be fed into the card slot; Step 3. The controller controls the number of test cards to be fed into the card slot, the rotation direction of the rotating motor, and the rotation speed of the rotating motor according to the designed test time; Step 4. The rotating motor stops, and the card to be sent into the card slot falls into the card outlet gap of the lower disc by gravity, and then is sent into the card outlet inspection port by the card outlet mechanism. At this time, the inspection time is equal to the waiting time.

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