A complex with soothing and repairing effects and preparation method thereof

Abstract

The present invention provides a soothing and repairing compound and a preparation method thereof, wherein the compound comprises the following raw materials by mass percentage: 32-58% of plant extract, 5-8% of Tremella polysaccharide, 1-6% of soluble proteoglycan, 2-3% of polypeptide, 0.1-0.15% of galactaric acid, 1-3% of methoxypropyl glucamide, 0.5-2% of mannitol, 0.5-5% of thickener, 0.1-2% of hydroxypropyl methylcellulose, 0.01-0.06% of preservative, and the balance of water. Through the synergistic effect of the raw materials of the present invention, skin irritation can be reduced, skin allergies, dryness and other problems can be effectively alleviated, and the skin can achieve a soothing effect. In addition, under the synergistic effect of the various raw material components of the present invention, a protective barrier can be formed on the surface of the damaged skin, and the damaged skin wound surface can be kept moist, and the moisture in the inflammatory cells can be absorbed to achieve the purpose of eliminating wound edema. It can also carry effective ingredients to penetrate into the inner layer of the skin, maintain the internal environment balance of the inner layer of the skin, effectively promote the growth and expression of fibroblasts, accelerate the repair of the inner and outer layers of the damaged skin, and effectively promote the repair and healing of the wound surface.

Description

Technical Field

[0001] The invention relates to the technical field of skin care products, and in particular to a complex with soothing and repairing effects and a preparation method thereof. Background Art

[0002] The skin is the part of the human body that is in direct contact with the outside world. It can protect the human body and resist most of the damage from the outside world. However, in daily life, abrasions, bruises, burns, sunburns, etc. can easily cause skin damage. In addition, for sensitive skin, due to the influence of external factors, it is also prone to allergic phenomena such as redness, swelling, itching, stinging, burning, dryness, and peeling. These skin problems plague our lives. At present, there are some care products on the market that can soothe and repair the skin, but the effects of most products are not long-lasting, the effects are not obvious, and the recovery time is long, which increases people's pain. Summary of the invention

[0003] In view of this, the present invention proposes a soothing and repairing complex and a preparation method thereof. The complex prepared by the present invention has good stability, can enhance the barrier protection and repair function of the skin, effectively promote skin repair and wound healing, and relieve skin allergies.

[0004] The technical solution of the present invention is achieved in this way:

[0005] A complex with soothing and repairing effects, comprising the following raw materials by mass percentage: 32-58% of plant extract, 5-8% of Tremella polysaccharide, 1-6% of soluble proteoglycan, 2-3% of polypeptide, 0.1-0.15% of galactaric acid, 1-3% of methoxypropyl glucamide, 0.5-2% of mannitol, 0.5-5% of thickener, 0.1-2% of hydroxypropyl methylcellulose, 0.01-0.06% of preservative, and the balance is water; the plant extract is one or more of Sanguisorba officinalis extract, Scutellaria baicalensis root extract, pineapple extract, Momordica grosvenori extract, and Kochia scoparia extract.

[0006] Furthermore, the polypeptide is a lysine polypeptide and a yeast polypeptide in a mass ratio of 1:(1-3).

[0007] Furthermore, the thickener is carbomer and / or xanthan gum; the preservative is one or more of propylparaben, ethylparaben, methylparaben, sodium benzoate and potassium sorbate.

[0008] Furthermore, the plant extract comprises the following raw materials by mass percentage: 22-28% of Sanguisorba officinalis extract, 20-34% of Scutellaria baicalensis root extract, 14-18% of pineapple extract, 16-20% of Momordica grosvenori extract, and 15-20% of Kochia scoparia fruit extract.

[0009] Furthermore, the complex comprises the following raw materials by mass percentage: 50% plant extract, 7% tremella polysaccharide, 5% soluble proteoglycan, 3% polypeptide, 0.15% galactaric acid, 2.5% methoxypropyl glucosamide, 2% mannitol, 4% thickener, 2% hydroxypropyl methylcellulose, and the balance water.

[0010] Furthermore, the complex comprises the following raw materials by mass percentage: 42% plant extract, 6% tremella polysaccharide, 4% soluble proteoglycan, 2% polypeptide, 0.12% galactaric acid, 2% methoxypropyl glucosamide, 1.5% mannitol, 3% thickener, 1.5% hydroxypropyl methylcellulose, and the balance water.

[0011] The preparation method of the complex having the effects of soothing and repairing comprises the following steps:

[0012] S1. Add hydroxypropyl methylcellulose to half of the formula water and stir to mix, then add plant extract, Tremella polysaccharide, soluble proteoglycan and polypeptide and stir to mix to obtain solution A;

[0013] S2. Add galactaric acid, methoxypropyl glucosamide, mannitol, thickener and preservative to the remaining half of the formula water and stir to obtain solution B. Stir solution A and solution B in the above S1, cool to room temperature, homogenize and filter to obtain a complex with soothing and repairing properties.

[0014] Furthermore, the stirring temperature is 30-45° C., the stirring rate is 80-120 r / min, and the stirring time is 8-15 min.

[0015] Furthermore, the complex can be used in skin care products, with the added amount of the complex being 0.5-20 wt %, or can be used alone.

[0016] Furthermore, the skin care products may be facial masks, facial cleansers, lotions, sunscreens, body lotions, shampoos, shower gels and other products.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] The soothing and repairing complex of the present invention can reduce skin irritation, effectively alleviate skin allergies, dryness and other problems through the synergistic effect of plant extracts, Tremella polysaccharides, soluble proteoglycans, polypeptides, etc., so that the skin can achieve a soothing effect. In addition, under the synergistic effect of each raw material component of the present invention, a protective barrier can be formed on the surface of the damaged skin, and the damaged skin wound surface can be kept moist, and the water in the inflammatory cells can be absorbed to achieve the purpose of eliminating wound edema. In addition, it can also play a role in inhibiting the growth of bacteria on the damaged skin, avoiding the infection of bacteria and other pathogens on the wound surface, and can also carry effective ingredients to penetrate into the inner layer of the skin, maintain the balance of the internal environment of the inner layer of the skin, effectively promote the growth and expression of fibroblasts, accelerate the repair of the inner and outer layers of the damaged skin, and thus effectively promote the repair and healing of the wound surface.

[0019] The present invention can effectively promote the absorption and utilization of nutrients by allergic or damaged skin through a reasonable raw material formula, maintain the balance of the internal and external environment of the skin, and thus accelerate the skin's allergy relief and repair effects. DETAILED DESCRIPTION

[0020] In order to better understand the technical content of the present invention, specific embodiments are provided below to further illustrate the present invention.

[0021] The plant extracts described in the present invention are: Sanguisorba officinalis extract, scutellaria baicalensis root extract, pineapple extract, momordica grosvenori fruit extract, kochia scoparia extract; Tremella polysaccharide is Tremella auricularia polysaccharide; and soluble proteoglycan is soluble proteoglycan (SOLUBLE PROTEOGLYCAN).

[0022] Unless otherwise specified, the experimental methods used in the embodiments of the present invention are all conventional methods.

[0023] Unless otherwise specified, the materials, reagents, etc. used in the embodiments of the present invention can be obtained from commercial sources.

[0024] Example 1

[0025] The complex with soothing and repairing effects of this embodiment includes the following raw materials, by mass percentage: 58% plant extract, 8% tremella polysaccharide, 1% soluble proteoglycan, 3% polypeptide composed of lysine polypeptide and yeast polypeptide in a mass ratio of 1:3, 0.15% galactaric acid, 3% methoxypropyl glucamide, 0.5% mannitol, 0.5% thickener composed of carbomer and xanthan gum in a mass ratio of 1:1, 2% hydroxypropyl methylcellulose, 0.03% ethylparaben as a preservative, and 23.82% water; the plant extract is composed of Sanguisorba officinalis extract, Scutellaria baicalensis root extract and pineapple extract in a mass ratio of 2:1:2.

[0026] The preparation method of the complex having the effects of soothing and repairing comprises the following steps:

[0027] S1. Add hydroxypropyl methylcellulose to half of the formula water, stir and mix at 45° C. and a stirring rate of 120 r / min for 15 minutes, keep the temperature and stirring rate unchanged, then add plant extract, Tremella polysaccharide, soluble proteoglycan, and polypeptide, stir and mix to obtain solution A;

[0028] S2. Add galactaric acid, methoxypropyl glucamide, mannitol, thickener and preservative to the remaining half of the formula water, stir and mix at 45°C and 120 r / min for 15 minutes to obtain solution B. Keeping the temperature and stirring rate unchanged, add solution A in S1 to solution B while stirring, cool to room temperature, homogenize and filter to obtain a complex with soothing and repairing properties.

[0029] Example 2

[0030] The complex with soothing and repairing effects of this embodiment includes the following raw materials, by mass percentage: 32% of plant extract, 5% of tremella polysaccharide, 6% of soluble proteoglycan, 2% of a polypeptide composed of a lysine polypeptide and a yeast polypeptide in a mass ratio of 1:1, 0.1% of galactaric acid, 1% of methoxypropyl glucamide, 2% of mannitol, 5% of a thickener composed of xanthan gum, 0.1% of hydroxypropyl methylcellulose, 0.06% of methylparaben as a preservative, and 46.74% of water; the plant extract is a scutellaria root extract.

[0031] The preparation method of the complex having the effects of soothing and repairing comprises the following steps:

[0032] S1. Add hydroxypropyl methylcellulose to half of the formula water, stir and mix at 30° C. and 80 r / min for 8 min, keep the temperature and stirring rate unchanged, then add plant extract, Tremella polysaccharide, soluble proteoglycan and polypeptide, stir and mix to obtain solution A;

[0033] S2. Add galactaric acid, methoxypropyl glucamide, mannitol, thickener and preservative to the remaining half of the formula water, stir and mix at 30°C and 80 r / min for 8 minutes to obtain solution B. Keeping the temperature and stirring rate unchanged, add solution A in S1 to solution B while stirring, cool to room temperature, homogenize and filter to obtain a complex with soothing and repairing properties.

[0034] Example 3

[0035] The plant extract of this embodiment includes the following raw materials by mass percentage: 22% of Sanguisorba officinalis extract, 25% of Scutellaria baicalensis root extract, 18% of pineapple extract, 20% of Momordica grosvenori extract, and 15% of Kochia scoparia fruit extract.

[0036] The raw materials of this embodiment have a soothing and repairing complex, and include the following raw materials by mass percentage: 42% plant extract, 6% tremella polysaccharide, 4% soluble proteoglycan, 2% polypeptide composed of lysine polypeptide and yeast polypeptide in a mass ratio of 1:3, 0.12% galactaric acid, 2% methoxypropyl glucamide, 1.5% mannitol, 3% thickener composed of carbomer and xanthan gum in a mass ratio of 1:3, 1.5% hydroxypropyl methylcellulose, 0.01% sodium benzoate as a preservative, and 37.87% water.

[0037] The preparation method of the complex having the effects of soothing and repairing comprises the following steps:

[0038] S1. Add hydroxypropyl methylcellulose to half of the formula water, stir and mix at 40° C. and 90 r / min for 10 min, keep the temperature and stirring rate unchanged, then add plant extract, Tremella polysaccharide, soluble proteoglycan and polypeptide, stir and mix to obtain solution A;

[0039] S2. Add galactaric acid, methoxypropyl glucamide, mannitol, thickener and preservative to the remaining half of the formula water, stir and mix at 40°C and 90 r / min for 12 minutes to obtain solution B. Keeping the temperature and stirring rate unchanged, add solution A in S1 to solution B while stirring, cool to room temperature, homogenize and filter to obtain a complex with soothing and repairing properties.

[0040] Example 4

[0041] The plant extract of this embodiment includes the following raw materials by mass percentage: 28% of Sanguisorba officinalis extract, 24% of Scutellaria baicalensis root extract, 14% of pineapple extract, 16% of Momordica grosvenori extract, and 18% of Kochia scoparia extract.

[0042] The raw materials of this embodiment have a soothing and repairing complex, and include the following raw materials by mass percentage: 50% plant extract, 7% tremella polysaccharide, 5% soluble proteoglycan, 3% polypeptide composed of lysine polypeptide and yeast polypeptide in a mass ratio of 1:2, 0.15% galactaric acid, 2.5% methoxypropyl glucamide, 2% mannitol, 4% thickener composed of carbomer and xanthan gum in a mass ratio of 1:2, 2% hydroxypropyl methylcellulose, 0.05% potassium sorbate as a preservative, and 24.30% water.

[0043] The preparation method of the complex having the effects of soothing and repairing comprises the following steps:

[0044] S1. Add hydroxypropyl methylcellulose to half of the formula water, stir and mix at 42° C. and a stirring rate of 100 r / min for 12 minutes, keep the temperature and stirring rate unchanged, then add plant extract, Tremella polysaccharide, soluble proteoglycan, and polypeptide, stir and mix to obtain solution A;

[0045] S2. Add galactaric acid, methoxypropyl glucamide, mannitol, thickener and preservative to the remaining half of the formula water, stir and mix at 42°C and a stirring rate of 100 r / min for 15 minutes to obtain solution B. Keeping the temperature and stirring rate unchanged, add solution A in S1 to solution B while stirring, cool to room temperature, homogenize, and filter to obtain a complex with soothing and repairing properties.

[0046] Comparative Example 1

[0047] In this comparative example, the raw material ratio of the composite material having the functions of allergy relief and repair is adjusted on the basis of Example 4, and the rest is the same as Example 4. The details are as follows:

[0048] The soothing and repairing complex of this comparative example includes the following raw materials, calculated by mass percentage: 16% of plant extract, 24% of tremella polysaccharide, 3% of soluble proteoglycan, 1.5% of polypeptide, 7% of galactaric acid, 10% of methoxypropyl glucamide, 8% of mannitol, 4% of thickener, 2% of hydroxypropyl methylcellulose, 0.05% of potassium sorbate as a preservative, and 24.30% of water.

[0049] Comparative Example 2

[0050] This comparative example adjusts the raw material components of the complex with allergy relief and repairing properties on the basis of Example 4. The raw materials of this comparative example do not contain plant extracts, and the rest are the same as Example 4. The details are as follows:

[0051] The soothing and repairing complex of this comparative example includes the following raw materials, calculated by mass percentage: 37% of tremella polysaccharide, 15% of soluble proteoglycan, 13% of a polypeptide composed of a lysine polypeptide and a yeast polypeptide in a mass ratio of 1:2, 0.15% of galactaric acid, 2.5% of methoxypropyl glucamide, 2% of mannitol, 4% of a thickener composed of carbomer and xanthan gum in a mass ratio of 1:2, 2% of hydroxypropyl methylcellulose, 0.05% of potassium sorbate as a preservative, and 24.30% of water.

[0052] The preparation method of the complex having the effects of soothing and repairing comprises the following steps:

[0053] S1. Add hydroxypropyl methylcellulose to half of the formula water, stir and mix at 42° C. and a stirring rate of 100 r / min for 12 minutes, keep the temperature and stirring rate unchanged, then add Tremella polysaccharide, soluble proteoglycan, and polypeptide, stir and mix to obtain solution A;

[0054] S2. Add galactaric acid, methoxypropyl glucamide, mannitol, thickener and preservative to the remaining half of the formula water, stir and mix at 42°C and a stirring rate of 100 r / min for 15 minutes to obtain solution B. Keeping the temperature and stirring rate unchanged, add solution A in S1 to solution B while stirring, cool to room temperature, homogenize, and filter to obtain a complex with soothing and repairing properties.

[0055] Comparative Example 3

[0056] This comparative example adjusts the raw material components of the complex having the functions of allergy relief and repair on the basis of Example 4. The raw materials of this comparative example do not contain polypeptides, and the rest are the same as Example 4. The details are as follows:

[0057] The raw materials of this embodiment have a soothing and repairing complex, and include the following raw materials by mass percentage: 50% plant extract, 8% tremella polysaccharide, 7% soluble proteoglycan, 0.15% galactaric acid, 2.5% methoxypropyl glucamide, 2% mannitol, 4% thickener composed of carbomer and xanthan gum in a mass ratio of 1:2, 2% hydroxypropyl methylcellulose, 0.05% potassium sorbate as a preservative, and 24.30% water.

[0058] The preparation method of the complex having the effects of soothing and repairing comprises the following steps:

[0059] S1. Add hydroxypropyl methylcellulose to half of the formula water, stir and mix at 42° C. and a stirring rate of 100 r / min for 12 minutes, keep the temperature and stirring rate unchanged, then add plant extract, Tremella polysaccharide, and soluble proteoglycan, stir and mix to obtain solution A;

[0060] S2. Add galactaric acid, methoxypropyl glucamide, mannitol, thickener and preservative to the remaining half of the formula water, stir and mix at 42°C and a stirring rate of 100 r / min for 15 minutes to obtain solution B. Keeping the temperature and stirring rate unchanged, add solution A in S1 to solution B while stirring, cool to room temperature, homogenize, and filter to obtain a complex with soothing and repairing properties.

[0061] Comparative Example 4

[0062] In this comparative example, the raw material components of the complex with allergy relief and repairing properties are adjusted on the basis of Example 4. The raw materials of this comparative example do not contain Tremella polysaccharide and soluble proteoglycan, and the rest are the same as Example 4.

[0063] The details are as follows:

[0064] The raw materials of this embodiment have a soothing and repairing complex, and include the following raw materials by mass percentage: 57% plant extract, 8% polypeptide composed of lysine polypeptide and yeast polypeptide in a mass ratio of 1:2, 0.15% galactaric acid, 2.5% methoxypropyl glucamide, 2% mannitol, 4% thickener composed of carbomer and xanthan gum in a mass ratio of 1:2, 2% hydroxypropyl methylcellulose, 0.05% potassium sorbate as a preservative, and 24.30% water.

[0065] The preparation method of the complex having the effects of soothing and repairing comprises the following steps:

[0066] S1. Add hydroxypropyl methylcellulose to half of the formula water, stir and mix at 42° C. and a stirring rate of 100 r / min for 12 minutes, keep the temperature and stirring rate unchanged, then add the plant extract and the polypeptide and stir and mix to obtain solution A;

[0067] S2. Add galactaric acid, methoxypropyl glucamide, mannitol, thickener and preservative to the remaining half of the formula water, stir and mix at 42°C and a stirring rate of 100 r / min for 15 minutes to obtain solution B. Keeping the temperature and stirring rate unchanged, add solution A in S1 to solution B while stirring, cool to room temperature, homogenize, and filter to obtain a complex with soothing and repairing properties.

[0068] According to the raw material formula and preparation method of the above Examples 1-4 and Comparative Examples 1-4, a complex with soothing and repairing properties was prepared, and the performance of each group of complexes was measured.

[0069] 1. Moisturizing

[0070] The complexes prepared in the above Examples 1-4 and Comparative Examples 1-4 were respectively prepared into aqueous solution samples with a concentration of 1.0 g / L, and then 2 ml of the aqueous solution samples of each group were measured and placed in an open weighing bottle, weighed, and immediately placed in a dryer with a saturated ammonium sulfate solution to dry, and then placed in an environment with a relative humidity of 80% for 8 hours, and the weighing bottle with the aqueous solution sample was taken out and weighed again, and then the moisture retention rate was determined.

[0071] Moisture retention rate (%) = M2 / M1×100%

[0072] Wherein, M1 is the total weight of the aqueous solution sample + weighing bottle before drying, g; M2 is the total weight of the aqueous solution sample + weighing bottle after drying, g. The experimental results are shown in Table 1 below.

[0073] Table 1 Moisturizing properties of the complex with soothing and repairing properties

[0074] Moisturizing rate (%) Example 1 40.85 Example 2 40.13 Example 3 41.32 Example 4 42.50 Comparative Example 1 38.47 Comparative Example 2 33.09 Comparative Example 3 37.15 Comparative Example 4 36.42

[0075] From the results in Table 1, it can be seen that the moisturizing performance of the composites prepared in Examples 1-4 of the present invention is better than that of the composites prepared in Comparative Examples 1-4, indicating that through a reasonable raw material ratio and the compounding of plant extracts with polypeptides, Tremella polysaccharides and soluble proteoglycans, the system's ability to bind water molecules can be effectively improved, the loss of water molecules can be reduced, and an effective moisturizing effect can be achieved.

[0076] 2. Fibroblast Growth Test

[0077] Human normal fibroblast primary cells were routinely cultured in a medium consisting of 10% PBS and 90% DMEM until the logarithmic growth phase, then digested with 0.25% trypsin and collected by centrifugation, and then resuspended in 90% DMEM medium containing 10% FBS, and then cultured at 5×10 4 The number of cells / mL was inoculated in a 96-well plate, cultured for 24 hours, replaced with serum-free DMEM medium and cultured for 24 hours, then the medium was aspirated, the compounds prepared in Examples 1-4 and Comparative Examples 1-4 were mixed with purified water to form a 1.0 g / L aqueous solution sample, and then cultured with cells respectively, and the medium to which EGF was added at 12.5 ng / mL was used as the positive control group, and only serum-free DMEM medium was added as the blank group, 10 μL MTT (0.5 mg / ml of thiazolyl blue) was added after 72 hours of culture, and after incubation in an incubator for 4 hours, the solution in the well was aspirated and 100 μL DMSO was added, and the absorbance OD value was detected at a wavelength of 570 nm after shaking, and then the cell proliferation rate was determined. The results are shown in Table 2 below.

[0078] Proliferation rate % = (OD value of drug administration group / OD value of blank control group-1) × 100%.

[0079] Table 2 Effects of the soothing and repairing complex on the growth of fibroblasts

[0080] Proliferation rate (%) Example 1 162 Example 2 158 Example 3 168 Example 4 174 Comparative Example 1 153 Comparative Example 2 130 Comparative Example 3 146 Comparative Example 4 135 Positive control group 182 Blank group 100

[0081] Fibroblasts have the effect of promoting wound repair and self-healing. As shown in Table 2, the composites prepared by Examples 1-4 of the present invention can effectively promote the growth and expression of fibroblasts, while the composites prepared by Comparative Examples 1-4 have a reduced fibroblast proliferation effect due to unreasonable raw material ratios or lack of plant extracts, polypeptides, Tremella polysaccharides and soluble proteoglycans, indicating that the raw material compatibility of the present invention is scientific and reasonable, especially the combination of plant extracts, polypeptides, Tremella polysaccharides and soluble proteoglycans can play a synergistic role in promoting skin repair.

[0082] 3. Wound healing experiment test results

[0083] 80 Kunming mice weighing 20-30g were selected, half male and half female, and the mice were anesthetized and fixed by intraperitoneal injection of 10mL of sodium pentobarbital aqueous solution, the hair of the central diameter 2cm×2cm area of ​​the back of the mice was cut as the experimental area, and povidone iodine was used for disinfection, and then 8 mice were randomly selected as the blank group, and the remaining mice were scratched with a scalpel in the experimental area to bleed but not cut, and a mouse skin damage model was established, and then the modeled mouse model was randomly divided into 9 groups, 8 mice in each group, and groups 1 to 9 corresponded to Examples 1-4, Comparative Examples 1-4 and positive groups, respectively. The groups of Examples 1-4 and Comparative Examples 1-4 were rubbed with the compounds of Examples 1-4 and Comparative Examples, respectively, at 10 am and 6 pm, with an application amount of 0.5mL, and then the skin of the experimental area was wrapped with gauze, and the blank group and the positive group were not treated in any way, and the skin of the experimental area was also wrapped with gauze at the same time. The wound healing of mice was observed every day and the time of wound healing was recorded. The criteria for wound healing were: scabs formed and fell off on the wound, no bleeding or pus discharge, and the formation of a pink and soft outer skin tissue.

[0084] Table 3 Wound healing time in mice experiment

[0085] Wound healing time (d) Example 1 7 Example 2 7 Example 3 6 Example 4 5 Comparative Example 1 9 Comparative Example 2 13 Comparative Example 3 11 Comparative Example 4 10 Positive group 16 Blank group -

[0086] The above results show that the composites prepared by Examples 1-4 of the present invention can effectively promote the repair of mouse wound skin and effectively promote its healing, while Comparative Examples 1-4 cannot effectively form an effective protective layer on the wound due to unreasonable raw material compatibility, lack of plant extracts (especially Sanguisorba officinalis extract, Scutellaria baicalensis root extract, pineapple extract, Momordica grosvenori extract, Kochia scoparia extract), lack of polypeptide components, and lack of Tremella polysaccharide and soluble proteoglycan, and also affect the repair effect, resulting in a longer wound healing time.

[0087] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A complex having soothing and repairing effects, characterized in that: The raw materials are as follows: 32-58% plant extract, 5-8% Tremella polysaccharide, 1-6% soluble proteoglycan, 2-3% polypeptide, 0.1-0.15% galactaric acid, 1-3% methoxypropyl glucamide, 0.5-2% mannitol, 0.5-5% thickener, 0.1-2% hydroxypropyl methylcellulose, 0.01-0.06% preservative, and the balance is water; The plant extract is one or more of Sanguisorba officinalis extract, Scutellaria baicalensis root extract, pineapple extract, Momordica grosvenori extract, and Kochia scoparia fruit extract; the polypeptide is a lysine polypeptide and a yeast polypeptide in a mass ratio of 1: (1-3).

2. The complex with soothing and repairing effects according to claim 1, characterized in that: The thickener is carbomer and / or xanthan gum; the preservative is one or more of propylparaben, ethylparaben, methylparaben, sodium benzoate and potassium sorbate.

3. The complex with soothing and repairing effects according to claim 1, characterized in that: The plant extract consists of the following raw materials by mass percentage: 22-28% of Sanguisorba officinalis extract, 20-34% of Scutellaria baicalensis root extract, 14-18% of pineapple extract, 16-20% of Momordica grosvenori extract, and 15-20% of Kochia scoparia fruit extract.

4. The complex with soothing and repairing effects according to claim 1, characterized in that: The complex comprises the following raw materials by mass percentage: 50% plant extract, 7% tremella polysaccharide, 5% soluble proteoglycan, 3% polypeptide, 0.15% galactaric acid, 2.5% methoxypropyl glucamide, 2% mannitol, 4% thickener, 2% hydroxypropyl methylcellulose, 0.05% potassium sorbate as a preservative, and the balance water.

5. The complex with soothing and repairing effects according to claim 1, characterized in that: The complex comprises the following raw materials by mass percentage: 42% plant extract, 6% tremella polysaccharide, 4% soluble proteoglycan, 2% polypeptide, 0.12% galactaric acid, 2% methoxypropyl glucamide, 1.5% mannitol, 3% thickener, 1.5% hydroxypropyl methylcellulose, 0.01% sodium benzoate as a preservative, and the balance water.

6. The method for preparing the complex with soothing and repairing effects according to any one of claims 1 to 5, characterized in that: The following steps are involved: S1. Add hydroxypropyl methylcellulose to half of the formula water and stir to mix, then add plant extract, Tremella polysaccharide, soluble proteoglycan and polypeptide and stir to mix to obtain solution A; S2. Add galactaric acid, methoxypropyl glucosamide, mannitol, thickener and preservative to the remaining half of the formula water and stir to obtain solution B. Stir solution A and solution B in the above S1, cool to room temperature, homogenize and filter to obtain a complex with soothing and repairing effects.

7. The method for preparing the complex with soothing and repairing effects according to claim 6, characterized in that: The stirring temperature is 30-45° C., the stirring speed is 80-120 r / min, and the stirring time is 8-15 min.