A neonicotinoid-containing pesticidal composition

Abstract

The present application belongs to the field of pesticide insecticide, and relates to a neonicotinoid-containing pesticide composition and use. The pesticide composition comprises active ingredient A and active ingredient B, the active ingredient A is a compound of formula (I), the active ingredient B is a neonicotinoid compound, and the mass ratio of the active ingredient A to the active ingredient B is 1:50-40:1. The pesticide composition of the present application has the advantages of synergism and resistance delay, and is used for preventing and treating resistant pests.

Description

Technical Field

[0001] This invention belongs to the field of pesticide technology, specifically relating to a pesticide composition containing neonicotinoids. Background Technology

[0002] Neonicotinoid insecticides inhibit acetylcholine receptors in the central nervous system of insect pests, thereby blocking normal nerve conduction and achieving an insecticidal effect. Since their introduction in the 1980s, neonicotinoid insecticides have gradually replaced traditional organophosphates and carbamates due to their high efficiency, broad spectrum, and low toxicity. However, the widespread use of neonicotinoid insecticides, along with their low volatility, high water solubility, and long half-life in soil, has led to insect resistance in pests and potential harm to non-target organisms.

[0003] In agricultural production, the control of various harmful insects mainly relies on the application of large quantities of pesticides. The excessive, frequent, and irrational use of pesticides leads to increasing resistance in harmful insects, making control increasingly difficult and causing more severe damage to crops. By mixing compounds of formula (I) with two or more neonicotinoid compounds that have different mechanisms of action, it is possible to control different pests simultaneously, broaden the control spectrum, improve pesticide efficacy, and reduce the development of pesticide resistance. Summary of the Invention

[0004] The purpose of this invention is to provide a pesticide composition containing neonicotinoid compounds that has synergistic effects, reduces resistance, and has low usage costs.

[0005] To achieve the above objectives, the technical solution adopted by the present invention is as follows: a pesticide composition containing neonicotinoids, comprising active ingredient A and active ingredient B, wherein active ingredient A is a compound of formula (I). The active ingredient B is a neonicotinoid compound;

[0006] Furthermore, the neonicotinoid compounds include flupyradifurone, flupyradifurone, thiamethoxam, acetamiprid, thiamethoxam, imidacloprid, dinotefuran, nitenpyram, nicotine, flupyrflurane, trifluorophenylpyrimidine, nitenpyram, or chlorothiazoline.

[0007] Furthermore, the neonicotinoid compounds are fipronil, flupyradifurone, thiamethoxam, thiamethoxam, acetamiprid, thiamethoxam, imidacloprid, dinotefuran, acetamiprid, and flupyradifurone.

[0008] Furthermore, the mass ratio between active ingredient A and active ingredient B is 1:50 to 40:1;

[0009] Furthermore, the mass ratio between active ingredient A and active ingredient B is 1:35 to 30:1 or any value between the above values;

[0010] Furthermore, the mass ratio of the compound of formula (I) to flufenacet is 1:27 to 25:1;

[0011] Furthermore, the mass ratio of the compound of formula (I) to flufenacet is 1:27 to 15:1;

[0012] Furthermore, the mass ratio of the compound of formula (I) to flonicamid is 1:20 to 30:1;

[0013] Furthermore, the mass ratio of the compound of formula (I) to flonicamid is 1:20 to 15:1;

[0014] Furthermore, the mass ratio of the compound of formula (I) to thiamethoxam is 1:26 to 18:1;

[0015] Furthermore, the mass ratio of the compound of formula (I) to thiamethoxam is 1:15 to 18:1;

[0016] Furthermore, the mass ratio of the compound of formula (I) to thiamethoxam is 1:50 to 18:1;

[0017] Furthermore, the mass ratio of the compound of formula (I) to thiamethoxam is 1:35 to 18:1;

[0018] Furthermore, the mass ratio of the compound of formula (I) to acetamiprid is 1:25 to 40:1;

[0019] Furthermore, the mass ratio of the compound of formula (I) to acetamiprid is 1:15 to 40:1;

[0020] Furthermore, the mass ratio of the compound of formula (I) to thiamethoxam is 1:24 to 12:1;

[0021] Furthermore, the mass ratio of the compound of formula (I) to imidacloprid is 1:20 to 30:1;

[0022] Furthermore, the mass ratio of the compound of formula (I) to fipronil is 1:24 to 15:1;

[0023] Furthermore, the mass ratio of the compound of formula (I) to acetamiprid is 1:22 to 16:1;

[0024] Furthermore, the mass ratio of the compound of formula (I) to flupyrfuranone is 1:24 to 30:1;

[0025] Furthermore, the mass ratio of the compound of formula (I) to flupyrfuranone is 1:24 to 10:1;

[0026] Furthermore, based on a total mass of 100 wt% of the pesticide composition, the sum of the contents of active ingredient A and active ingredient B in the pesticide composition is 0.5% to 90%.

[0027] Furthermore, the sum of the contents of active ingredient A and active ingredient B in the pesticide composition is 1% to 85%;

[0028] Furthermore, in addition to the active ingredient, the pesticide composition also includes agriculturally acceptable auxiliary ingredients, which are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists or carriers.

[0029] Furthermore, the pesticide composition further includes an adjuvant selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists, and carriers;

[0030] The wetting agent is selected from one or more of the following: alkylbenzene sulfonates, alkylnaphthalene sulfonates, lignin sulfonates, sodium dodecyl sulfate, sodium dioctyl succinate sulfonate, α-olefin sulfonates, alkylphenol polyoxyethylene ethers, castor oil polyoxyethylene ethers, alkylphenol ethoxylates, fatty alcohol ethoxylates, sodium fatty alcohol polyoxyethylene ether sulfate, silkworm excrement, soapberry powder, soapberry powder, SOPA, detergents, emulsifiers 2000 series, and wetting and penetrating agents F; and / or

[0031] The dispersant is selected from one or more of the following: lignin sulfonates, alkyl naphthalene sulfonates formaldehyde condensates, naphthalene sulfonates, tristyrylphenol ethoxylate phosphates, fatty alcohol ethoxylates, alkylphenol polyoxyethylene ethers, alkylphenol polyoxyethylene ether methyl ether condensates sulfates, fatty amine polyoxyethylene ethers, glycerol fatty acid ester polyoxyethylene ethers, polycarboxylates, polyacrylic acids, phosphates, EO-PO block copolymers, and EO-PO graft copolymers; and / or

[0032] The emulsifier is selected from one or more of the following: calcium dodecylbenzenesulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, phenethylphenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styrene-phenol polyoxyethylene ether, castor oil polyoxyethylene ether, and alkylphenol ether phosphate; and / or

[0033] The thickener is selected from one or more of xanthan gum, organobentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose, and silica; and / or

[0034] The disintegrant is selected from one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid, and tartaric acid; and / or

[0035] Antifreeze is selected from one or more of alcohols, alcohol ethers, chlorinated hydrocarbons, and inorganic salts; and / or

[0036] Defoamer selected from C 10 -C 20 Saturated fatty acid compounds, silicone oil, silicone compounds, C8-C 10 One or more of the fatty alcohols; and / or

[0037] The solvent is selected from one or more of benzene, toluene, xylene, mesitylene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethylformamide, cyclohexanone, hydrocarbon carbonates, diesel oil, solvent oil, vegetable oil, vegetable oil derivatives, and water; and / or

[0038] The preservative is selected from one or more of propionic acid, sodium propionate, sorbic acid, sodium sorbate, potassium sorbate, benzoic acid, sodium benzoate, sodium p-hydroxybenzoate, methyl p-hydroxybenzoate, Kathon, and 1,2-benzisothiazolin-3-one; and / or

[0039] The stabilizer is selected from one or more of the following: disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-cresol, triethanolamine oleate, epoxidized vegetable oil, kaolin, bentonite, attapulgite, silica, talc, montmorillonite, and starch; and / or

[0040] Synergists are selected from synergistic phosphorus, synergistic ether; and / or

[0041] The carrier is selected from one or more of the following: ammonium salts, ground natural minerals, ground artificial minerals, silicates, resins, waxes, solid fertilizers, water, organic solvents, mineral oils, vegetable oils, and vegetable oil derivatives.

[0042] Furthermore, the pesticide composition can be prepared into an agriculturally permissible formulation, wherein the formulation is selected from solid and / or liquid formulations;

[0043] Furthermore, the solid dosage forms include powders, granules, balls, tablets, strips, wettable powders, oil-dispersible powders, emulsion powders, water-dispersible granules, emulsion granules, water-dispersible tablets, soluble powders, soluble tablets, or soluble granules;

[0044] Furthermore, the liquid formulation includes soluble agents, colloids, oils, spreading oils, emulsions, latexes, dispersible liquids, ointments, water emulsions, oil emulsions, microemulsions, lipids, suspensions, microcapsule suspensions, oil suspensions, dispersible oil suspensions, suspensions, microcapsule suspension-suspensions, microcapsule suspension-water emulsions, or microcapsule suspension-suspension emulsions;

[0045] Furthermore, the solid formulation is selected from wettable powders and water-dispersible granules; the liquid formulation is selected from emulsifiable concentrates, water emulsions, microemulsions, suspensions, suspension emulsions, and dispersible oil suspensions.

[0046] The application of the pesticide composition described in this invention in the control of agricultural and forestry pests and sanitary pests;

[0047] The pesticide composition described in this invention can be used to control pests on fruit trees, vegetables, ornamental plants, tea, cotton, and cereal crops.

[0048] Furthermore, the aforementioned agricultural and forestry pests and sanitary pests are pests belonging to the orders Hemiptera, Thysanoptera, Lepidoptera, and Diptera.

[0049] Furthermore, the aforementioned Hemiptera pests include: green stink bugs (Acrosternum hilare), chinch bugs (Blissus leucopterus), potato blind bugs (Calocoris norvegicus), aphids, scales, whiteflies, leafhoppers, pea aphids (Acrythosiphon pisum), Adelges spp., cabbage whiteflies (Aleurodes proletella), and spiral whiteflies (Aleurodicus). The following species are listed: * *disperses*, *Aleurothrixus floccosus* (woolly whitefly), *Aluacaspis spp.*, *Aonidiella aurantii*, *Aphis spp.*, *Aphis gossypii* (cotton aphid), *Aphis pomi*, *Aulacorthum solani* (foxglove aphid), *Bemisia spp.* (whitefly), *Bemisia argentifolii*, *Bemisia tabaci* (sweet potato whitefly), *Brachycolus noxius*, *Brachycorynella asparagi* (asparagus aphid), *Brevennia rehi*, and *Brevicoryne*. Species of the genera *Ceroplastes* (brassicae), *Ceroplastes spp.*, *Ceroplastes rubens* (red wax scale), *Chionaspis* (spp.), *Chrysomphalus* (spp.), *Dysaphis plantaginea* (rosy apple aphid), and *Empoasca* (green leafhopper).Apple cotton aphid (Eriosomalanigerum), cottony cushion scale (Icerya purchasi), mango leafhopper (Idioscopus nitidulus), planthopper (Laodelphaxstriatellus), oyster scale (Lepidosaphes spp.), long-tubed aphid (Macrosiphum spp.), euphorbiae, granarium, rosae, quadrilineatus (aster leafhopper), frimbiolata, dirhodum, longicornis, myzus spp., persicae (green peach aphid) The following species are listed: *Nephotettix* spp., *Nephotettix cinctipes* (green leafhopper), *Nilaparvata lugens*, *Parlatoria pergandii*, *Peregrinus maidis* (corndelphacid), *Philaenus* spp., *Phylloxeravitifoliae* (grape phylloxera), *Physokermes piceae* (spruce bud scale), *Planococcus* spp. (mealyptus), *Pseudococcus* spp. (mealyptus), and *Pseudococcus brevipes* (pineapple mealybug). The species *Mealybug*, *Quadraspidiotus perniciosus* (San Josescale), and *Rhopalosiphum spp.*The following aphids are listed: * *Rhopalosiphum maida* (corn leaf aphid), * *Rhapalosiphum padi* (oat bird-cherry aphid), * *Saissetia spp.*, * *Saissetia oleae*, * *Schizaphis graminum* (green bug), * *Sitobion avenae* (English grain aphid), * *Sogatella furcifera*, * *Therioaphis spp.*, * *Toumeyella spp.*, * *Trialeurodes spp.*, and * *Trialeurodes vaporariorum*.

[0050] Furthermore, the aforementioned Thysanoptera pests include: *Thrips palmi* Karny, *Thrips tabaci*, *Frankliniella fusca* (tobaccothrips), *Frankliniella occidentalis* (western flowerthrips), *Frankliniella shultzei*, *Frankliniella williamsi* (cornthrips), *Heliothrips haemorrhaidalis* (greenhouse thrips), *Riphiphorothrips cruentatus*, *Scirtothrips* spp., and *Scirtothrips citri* (citrus thrips). Thrips, yellow tea thrips (Scirtothripsdorsalis), Taeniothrips rhopalantennalis, and thrips spp.

[0051] Furthermore, the aforementioned Lepidoptera pests include: *Adoxophyes spp.*, *Adoxophyes orana*, *Agrotis spp.* (root cutter), *Agrotis ipsilon* (black cutworm), *Alabamaargillacea* (cotton leafworm), *Amorbia cuneana*, *Amyelosis transitella* (navel orange moth), *Anacamptodes defectaria*, *Anarsia lineatella* (peach twig borer), *Anomis sabulifera* (jute looper), *Anticarsia gemma ta lis*, *Archips argyrospila* (fruittree leafroller), and *Archips* (rose leafroller). *Argyrotaenia spp.* (rose leaf roller), *Argyrotaenia citrana* (orange tortrix), *Autographa gamma*, *Bonagota cranaodes*, *Borbo cinnara* (rice leaf folder), *Bucculatrix thurberiella* (cotton leafperforator), *Caloptilia spp.* (leaf miners), *Ca pua reticulana*, *Carposina niponensis* (peach fruit moth), *Chilo spp.*, *Chlumetia transversa* (mango shoot borer), *Choristoneurarosaceana* (obliquebanded rose leaf roller) Leafroller), and species of the genus Chrysodeixis spp.The following species are listed: *Cnaphalocerus medinalis* (grass leafroller), *Colias* spp., *Conpomorpha cramerella*, *Cossus cossus* (carpenter moth), *Crambus* spp. (soil webworms), *Cydiafunebrana* (plum fruit moth), *Cydia molesta* (oriental fruit moth), *Cydia nignicana* (pea moth), *Cydiapomonella* (codling moth), *Darna diducta*, and *Diaphania* spp. (stem borer). *Diatraea* spp. (stalk borers), *Diatraeas accharalis* (sugarcane borer), *Diatraea graniosella* (southwester corn borer), *Earias* spp. (cotton bollworm), *Earias insulata* (Egyptian cotton bollworm), *Earias vitella* (rough northern bollworm), *Ecdytopopha aurantianum*, *Elasmopalpus lignosellus* (lesser cornstalk borer), *Epiphysias postruttana* (light brown apple moth), *Ephestia* spp. (flour moths), *Ephestia* cautella (almond moth), Tobacco moth (Ephestia elutella), Mediterranean flour moth (Ephestia kuehniella), and species of the genus Epimeces (Epimeces spp.).), Epinotia aporema, Erionotathrax (banana skipper), Eupoecilia ambiguella (grape leafroller), Euxoa auxiliaris (army cutworm), Feltia spp. (root cutter), Gortyna spp. (stemborers), Grapholitamolesta (oriental fruit borer).

[0052] (oriental fruit moth)), Hedylepta indicate (bean leaf moth), Helicoverpa sp p. (noctus moth), Helicoverpa armigera, Helicoverpa zea, Heliothis spp., Heliothis virescens, Hellula undalis (cabbage webworm), Indarbela spp. (root borers), Keiferia lycopersicella, Leucinodes orbonalis, Leucoptera malifoliella, Lithocollectis spp., Lobesia botrana (grape fruit moth) The following species are listed: fruitmoth, Loxagrotis spp., Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil palm bagworm), and Malacosoma spp.(tent caterpillars), cabbage armyworm (Mamestra brassicae), bean pod borer (Maruca testulalis), bagworm (Metisa plana), true armyworm (Mythimna unipuncta), elegantalis (Neoleucinodes elegantalis), depunctalis (Nymphula depunctalis), winter inchworm (Operophtherabrumata), European corn borer (Ostrinia nubilalis), Oxydiavesulia, common currant tortrix (Pandemis cerasana), brown apple tortrix (Pandemis heparana), African swallowtail butterfly (Papilio demodocus), pink bollworm (Pectinophora gossypiella). The following species are listed: bollworm, Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phylloocnisitis citrella (citrus leafminer), Phyllonorycter spp. (leek moth), Pieris rapae (cabbage white butterfly), Plathapena scabra (alfalfa green armyworm), Plodia interpunctella (Indian grain moth), Plutellaxylostella (diamondback moth), Polychrosis viteana (grape leafroller), Prays endocarpa (citrus fruit borer), and Prays endocarpa (olive borer). oleae (olive moth), species of the genus Pseudaletia (Pseudaletia spp.).(Noctus), Spodoptera litura Fabricius, Pseudaletia unipunctata (armyworm), Pseudoplusia includes (soybean noctus), Rachiplusia nu, Chilo suppressalis (Walker), Scirpophaga incertulas, Sesamia spp. (stemborers), Sesamia inferens (pink rice stem borer), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp., Spodoptera exigua, Spodoptera fugiperda), Southern armyworm (Spodoptera oridania), Synanthedon spp., Thecla basilides, Thermisia gemmatalis, clothes moth (Tineola bisselliella), cabbage white butterfly (Trichoplusia ni), cabbage white butterfly (Pierisrapae Linne), tomato leafminer (Tuta absoluta).

[0053] Furthermore, the hemiptera pests mentioned include whiteflies, rice planthoppers, and aphids;

[0054] Furthermore, the aforementioned Thysanoptera pests include tobacco thrips, palm thrips, flower thrips, western flower thrips, and tea thrips;

[0055] Furthermore, the lepidopteran pests mentioned include diamondback moth, beet armyworm, cotton bollworm, rice stem borer, and cabbage caterpillar;

[0056] The present invention also provides a method of using the neonicotinoid-containing pesticide composition as described above, specifically applying it in an effective dose to the pest to be controlled or its growth medium.

[0057] The pesticide composition of the present invention has the following advantages:

[0058] 1) The pesticide composition of the present invention exhibits a synergistic effect within a certain ratio range, resulting in significant control effects;

[0059] 2) The pesticide composition has two active ingredients with unique mechanisms of action, which can effectively protect against resistant pests and extend the product's service life. Detailed Implementation

[0060] The present invention will be further described below with reference to the embodiments. The percentages in the embodiments are all weight percentages, but the present invention is not limited thereto.

[0061] The compositions of the present invention can be provided in formulation form. They can be formulated as suspensions, water-dispersible granules, emulsions, pellets, wettable powders, dispersible oil suspensions, etc., as needed. The content of the active ingredient in the compositions of the present invention depends on the application rate when used alone, as well as on the mixing ratio and the degree of synergistic effect. The optimal range of active ingredient content varies depending on the formulation type of the composition.

[0062] Formulation preparation examples

[0063] Example 1:

[0064] 25% Formula (I) Compound·Fluoropyram Suspension (5:20)

[0065] Formula: 5% compound of formula (I), 20% flufenoxam, 2.5% fatty alcohol polyoxyethylene ether, 2% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 4% styrene-phenol polyoxyethylene ether phosphate, 0.5% magnesium aluminum silicate, 0.25% xanthan gum, 1% sodium sorbate, 5% ethylene glycol, 0.5% silicone oil, deionized water to make up the balance;

[0066] Preparation method: Add the active ingredient to the wetting and dispersing agent and defoamer, use zirconia beads, and wet pulverize with a sand mill to D. 90 (90% of the particles have a particle size) < 5 μm to obtain a pulverized slurry. Thickener, antifreeze, and preservative are added to the pulverized slurry and mixed evenly. Deionized water is added to make up to 100%, and the mixture is sheared at high speed to obtain a suspension product.

[0067] Example 2:

[0068] 28% Formula (I) Compound·Fluoride Acetate Suspension (21:7)

[0069] Formula: 21% compound of formula (I), 7% flonicamid, 2.5% fatty alcohol polyoxyethylene ether, 2% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 3% styrene-phenol polyoxyethylene ether phosphate, 2% lignin sulfonate, 0.5% magnesium aluminum silicate, 0.25% xanthan gum, 1.2% sodium sorbate, 5% ethylene glycol, 0.5% silicone oil, deionized water to make up the balance;

[0070] Preparation method: Same as in Example 1.

[0071] Example 3:

[0072] 30% Formula (I) compound·thiamethoxam suspension (15:15)

[0073] Formula: 15% compound of formula (I), 15% thiamethoxam, 3% isotridecyl alcohol polyoxyethylene ether, 2.5% alkylaryl polyoxyethylene ether polyoxypropylene ether, 4% alkylphenol polyoxyethylene ether sulfate, 1% naphthalene sulfonate formaldehyde condensate, 0.8% magnesium aluminum silicate, 0.2% xanthan gum, 1% sodium sorbate, 5% ethylene glycol, 0.5% silicone oil, deionized water to make up the balance;

[0074] Preparation method: Same as in Example 1.

[0075] Example 4:

[0076] 21% Formula (I) Compound·Thiamethoxam Suspension Concentrate (6:15)

[0077] Formula: 6% compound of formula (I), 15% thiamethoxam, 2.5% fatty alcohol polyoxyethylene ether, 2% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 4% styrene-phenol polyoxyethylene ether phosphate, 0.5% magnesium aluminum silicate, 0.25% xanthan gum, 1% citric acid, 5% ethylene glycol, 0.5% silicone oil, deionized water to make up the balance;

[0078] Preparation method: Same as in Example 1.

[0079] Example 5:

[0080] 19% Formula (I) Compound·Fluoropyranone Suspension (4:15)

[0081] Formula: 4% compound of formula (I), 15% flupyrrolidone, 1% naphthalene sulfonate formaldehyde condensate, 2% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 4% styrene phenol polyoxyethylene ether phosphate, 0.5% magnesium aluminum silicate, 0.25% xanthan gum, 0.15% methylisothiazolinone, 5% glycerin, 0.5% silicone oil, deionized water to make up the balance;

[0082] Preparation method: Same as in Example 1.

[0083] Example 6:

[0084] 16% Formula (I) Compound·Thiamethoxam Granules (10:6)

[0085] Formula: 10% compound of formula (I), 6% thiamethoxam, 1% sodium polycarboxylate, 3% sodium lignosulfonate, 2% polyvinyl alcohol, and diatomaceous earth particles to make up the balance;

[0086] Preparation method: The active ingredient, dispersant, and adjuvant are mixed evenly to form a master powder. The master powder and carrier are added together into a coating granulator and stirred. While stirring, the prepared binder aqueous solution is added. After being fully mixed, the mixture is discharged, dried, and sieved to obtain the granules of the present invention.

[0087] Example 7:

[0088] 20% Formula (I) Compound·Thiamethoxam Granules (2:18)

[0089] Formula: 2% compound of formula (I), 18% thiamethoxam, 1% sodium polycarboxylate, 3% sodium lignosulfonate, 2.5% polyvinyl acetate, and diatomaceous earth granules to make up the balance;

[0090] Preparation method: Same as in Example 6.

[0091] Example 8:

[0092] 10% Formula (I) Compound·Fenlotinib Granules (3:7)

[0093] Formula: 3% compound of formula (I), 7% fipronil, 1% sodium polycarboxylate, 3% sodium lignosulfonate, 1% naphthalenesulfonate formaldehyde condensate, and granulated ceramsite to make up the balance;

[0094] Preparation method: Same as in Example 6.

[0095] Example 9:

[0096] 40% Formula (I) Compound·Thiamethoxam Wettable Powder (5:35)

[0097] Formula: 5% compound of formula (I), 35% thiamethoxam, 5% naphthalenesulfonate formaldehyde condensate, 10% tea saponin, 2% sodium dodecyl sulfate, 2% citric acid, kaolin to make up the balance;

[0098] Preparation method: The active ingredients, dispersant, wetting agent and filler are mixed according to the formula ratio, stirred evenly in a stirring tank, and then pulverized and mixed evenly multiple times by an air jet mill to prepare the wettable powder of the composition of the present invention.

[0099] Example 10:

[0100] 35% Formula (I) Compound·Imidacloprid Wettable Powder (30:5)

[0101] Formula: 30% of compound (I), 5% imidacloprid, 5% naphthalenesulfonate formaldehyde condensate, 10% tea saponin, 2% sodium dodecyl sulfate, and kaolin to make up the balance;

[0102] Preparation method: Same as in Example 9.

[0103] Example 11:

[0104] 36% Formula (I) Compound·Fipronil Wettable Powder (14:22)

[0105] Formula: 14% compound of formula (I), 22% fipronil, 5% naphthalenesulfonate formaldehyde condensate, 15% tea saponin, 2% sodium dodecyl sulfate, kaolin to make up the balance;

[0106] Preparation method: Same as in Example 9.

[0107] Example 12:

[0108] 60% Formula (I) Compound·Acetaminophen Wettable Powder (24:36)

[0109] Formula: 24% compound of formula (I), 36% acetamiprid, 6% sodium lignosulfonate, 2% sodium dodecyl sulfate, 10% tea saponin, 10% silica, and kaolin to make up the balance;

[0110] Preparation method: Same as in Example 9.

[0111] Example 13:

[0112] 50% Formula (I) compound·fluoxetine water-dispersible granules (10:40)

[0113] Formula: 10% compound of formula (I), 40% flonicamid, 6% sodium polycarboxylate, 2% dispersant NNO, 6% naphthalene sulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 4% sodium sulfate, and kaolin to make up the balance;

[0114] Preparation method: According to the formula ratio, the active ingredients are added to the carrier, and surfactants and other functional additives are added to it. After mixing, the mixture is pulverized by air jet and then an appropriate amount of water is added. The mixture is then kneaded, granulated, dried and sieved to obtain the water-dispersible granule product.

[0115] Example 14:

[0116] 60% Formula (I) compound·thiamethoxam water-dispersible granules (12:48)

[0117] Formula: 12% compound of formula (I), 48% thiamethoxam, 6% sodium polycarboxylate, 8% naphthalene sulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 4% sodium sulfate, and kaolin to make up the balance;

[0118] Preparation method: Same as in Example 13.

[0119] Example 15:

[0120] 54% Formula (I) Compound·Acetamiprid Water Dispersible Granules (48:6)

[0121] Formula: 48% compound of formula (I), 6% acetamiprid, 6% sodium polycarboxylate, 7.5% naphthalene sulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 4% sodium sulfate, and kaolin to make up the balance;

[0122] Preparation method: Same as in Example 13.

[0123] Example 16:

[0124] 45% Formula (I) Compound·Imidacloprid Water Dispersible Granules (35:10)

[0125] Formula: 35% of compound (I), 10% imidacloprid, 2% sodium lignosulfonate, 3.5% sodium polycarboxylate, 8% naphthalenesulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 4% sodium sulfate, and kaolin to make up the balance;

[0126] Preparation method: Same as in Example 13.

[0127] Example 17:

[0128] 49% Formula (I) Compound·Dinotefuran Water Dispersible Granules (14:35)

[0129] Formula: 14% compound of formula (I), 35% fipronil, 6% sodium lignosulfonate, 8% naphthalenesulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 4% sodium sulfate, and kaolin to make up the balance;

[0130] Preparation method: Same as in Example 13.

[0131] Example 18:

[0132] 55% Formula (I) Compound·Acetaminophen Water Dispersible Granules (25:30)

[0133] Formula: 25% compound of formula (I), 30% acetamiprid, 6% sodium polycarboxylate, 8% naphthalenesulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 10% silica, and kaolin to make up the balance;

[0134] Preparation method: Same as in Example 13.

[0135] Indoor bioactivity assay

[0136] The examples refer to the guidelines for indoor bioassay of pesticides, Part 6: Insect immersion method NY / T 1154.6-2006; Part 7: Determination of the combined effects of mixtures NY / T 1154.7-2006; Part 9: Spraying method NY / T 1154.9-2008; and Part 14: Leaf immersion method NY / T 1154.14-2008, etc.

[0137] Specific indoor toxicity tests:

[0138] 1) Experimental target: Thrips

[0139] Test method: Drug film rolling tube method;

[0140] Test insect source: thrips (Thrips tabaci);

[0141] Reagent preparation: Prepare a stock solution using organic solvent (acetone) for the test reagent, and then prepare 5 to 7 series of mass concentrations using 0.1% Tween 80 aqueous solution according to the ratio or differential method.

[0142] Experimental treatment:

[0143] Immersion tubes: Glass tubes 7 cm high and 1.5 cm in diameter. Within the concentration range determined in the preliminary experiment, the test reagent was diluted with acetone to five concentrations. 250 μL of each concentration was added to the glass tube using a pipette. The glass tube was then held horizontally, and the tube was slowly rolled with the palm of the hand to accelerate the evaporation of the reagent, ensuring it adhered evenly to the inner wall of the tube. Each tube constituted one replicate, with eight replicates for each concentration. The acetone-immersion tube served as a control.

[0144] Leaf dipping: Fresh cabbage leaves were punched into small round pieces with a diameter of 1 cm using a puncher. Each piece was dipped in a pesticide of a different concentration for 10 seconds, with a 0.1% Tween 80 leaf dip used as a control. The treated leaves were then placed on filter paper to dry and placed into glass tubes of the corresponding pesticide concentrations using tweezers. Twenty adult thrips were transferred into the glass tubes using a suction device, and the tube openings were sealed with 200-mesh gauze.

[0145] The treated test insects were placed in a rearing room with a temperature of 25±0.1℃, a humidity of 60%~80%, and a light duration of L:D=16h:8h for rearing and observation.

[0146] Investigation time: Thrips were observed 48 hours later. Thrips were gently touched with the tip of a paintbrush. Thrips that did not move were considered dead. The total number of thrips and the number of dead thrips were recorded.

[0147] 2) Experimental targets: rice planthoppers and whiteflies

[0148] Test method: spray method;

[0149] Test insects: healthy adult insects with uniform growth and development;

[0150] Reagent preparation: Dissolve the test reagent in acetone and prepare five series of concentrations using a 0.1% Tween 80 aqueous solution.

[0151] Experimental treatment: Use an insect aspirator to select no fewer than 15 test insects with the same physiological state and place them in a petri dish. Then place the petri dish in the bottom tray of a potter spray tower for quantitative spraying. The spray volume is 1 mL. After the liquid settles for 1 minute, remove the test insects.

[0152] Each treatment was repeated four times, with a blank treatment serving as a control. The treated insects were then reared in an AI-controlled culture room at 25±1℃, with a light duration of L:D = 16h:8h and a relative humidity of 65±5%.

[0153] Investigation method: The mortality of test insects was investigated 48 hours after the treatment with the agent. The criteria for judging the mortality of test insects were obvious shrinkage of the insect body or inability to crawl normally when punctured. The total number of insects and the number of dead insects were recorded.

[0154] 3) Test target: Aphids

[0155] Experimental method: Insect immersion method;

[0156] Test insects: healthy, uniformly grown and developed second-instar nymphs;

[0157] Reagent preparation: Dissolve the test reagent in acetone and prepare five series of concentrations using a 0.1% Tween 80 aqueous solution.

[0158] Experimental treatment: Second-instar larvae with consistent physiological condition and indoor rearing were selected. The test insects were immersed in the drug solution for 5 seconds using an insect dipping device. 15 insects were treated per treatment, and the treatment was repeated 4 times. The control group was treated with 0.1% Tween 80 aqueous solution. After treatment, the insects were transferred to a 9.0 cm diameter culture dish lined with filter paper for rearing. Fresh leaves were changed daily.

[0159] The treated test insects were raised in an artificial intelligence culture room at 25±1℃, with a light duration of L:D = 14h:10h and a relative humidity of 65%±5%.

[0160] Investigation method: The mortality of test insects was investigated 48 hours after the treatment with the agent. The criteria for judging the mortality of test insects were obvious shrinkage of the insect body or inability to crawl normally when punctured. The total number of insects and the number of dead insects were recorded.

[0161] 4) Experimental target: Diamondback moth

[0162] Experimental method: A combination of leaf soaking and insect soaking;

[0163] Test insects: healthy, uniformly grown and developed 3rd instar larvae;

[0164] Reagent preparation: Dissolve the test reagent in acetone and prepare five series of concentrations using a 0.1% Tween 80 aqueous solution.

[0165] Experimental treatment: Fresh cabbage slices were placed in the drug solution with tweezers and soaked for 10 seconds. After the solution was allowed to air dry, the cabbage slices were placed in a petri dish lined with moisturizing filter paper. Twenty third-instar larvae were placed in the drug solution for 5 seconds. Excess solution was absorbed with filter paper, and the test insects were placed in a petri dish with leaves soaked at the corresponding concentration.

[0166] Each treatment was repeated four times, with a blank treatment serving as a control. The treated insects were then reared in an AI-controlled culture room at 26±1℃, with a light duration of L:D = 16h:8h and a relative humidity of 60%.

[0167] Investigation method: The mortality of test insects was investigated 48 hours after the treatment with the agent. The criteria for judging the mortality of test insects were obvious shrinkage of the insect body or inability to crawl normally when punctured. The total number of insects and the number of dead insects were recorded.

[0168] Data statistics and analysis:

[0169] Based on the survey data, the corrected mortality rates for each treatment were calculated. The calculations were performed using formulas (1) and (2), and the results were rounded to two decimal places.

[0170]

[0171] In the formula:

[0172] P – Mortality rate, expressed as a percentage (%);

[0173] K represents the number of dead insects, in heads;

[0174] N represents the total number of insects treated, in units of heads.

[0175]

[0176] In the formula:

[0177] P1 – Corrected mortality rate, in percentage (%);

[0178] P t —The mortality rate is expressed as a percentage (%).

[0179] P0 – Mortality rate in the blank control group, expressed as a percentage (%).

[0180] If the control mortality rate is <5%, no correction is needed; if the control mortality rate is between 5% and 20%, correction should be made according to formula (2); if the control mortality rate is >20%, the experiment needs to be repeated.

[0181] The data was processed using probability value analysis. The DPS statistical analysis system can be used to analyze the data and determine the toxicity regression line and LC. 50 The values, their 95% confidence limits, and correlation coefficients r are used to evaluate the activity of the test reagent on the biological sample.

[0182] The co-toxicity coefficient (CTC value) of the mixture is calculated using the following formula:

[0183]

[0184] In the formula:

[0185] ATI – Actual Measured Toxicity Index of Mixtures;

[0186] S – LC50 of standard insecticides 50 The unit is milligrams per liter (mg / L);

[0187] M – LC of the mixture 50 The unit is milligrams per liter (mg / L).

[0188] TTI = TI A *P A +TI B *P B

[0189] In the formula:

[0190] TTI – Theoretical Toxicity Index of Mixtures;

[0191] TI A —A. Toxicity index of drug A;

[0192] P A —Percentage content of drug A in the mixture, expressed as percentage (%);

[0193] TI B —Toxicity index of drug B;

[0194] P B —Percentage content of agent B in the mixture, expressed as percentage (%).

[0195]

[0196] In the formula:

[0197] CTC – Cotoxicity Coefficient;

[0198] ATI – Actual Measured Toxicity Index of Mixtures;

[0199] TTI – Theoretical Toxicity Index of Mixtures.

[0200] The co-toxicity coefficient of the compound is ≥120, which shows a synergistic effect; CTC≤80 shows an antagonistic effect; and 80<CTC<120 shows an additive effect.

[0201] Experimental results:

[0202] 1) Combined toxicity of mixed thrips:

[0203] Tables 1-3 show the LC50 of compound (I) for thrips. 50 The concentration was 0.9339 mg / L. Compound (I) exhibited good synergistic effects with thrips when mixed with fipronil, flonicamid, and thiamethoxam. When the mass ratio of compound (I) to fipronil was 1:27–25:1, the co-toxicity coefficient was greater than 80, showing an additive or synergistic effect. Among them, the co-toxicity coefficient was greater than 120 when the mass ratio was 1:27–15:1, showing a good synergistic effect. When the mass ratio of compound (I) to flonicamid was 1:20–20:1, the co-toxicity coefficient was greater than 80, showing an additive or synergistic effect. Among them, the co-toxicity coefficient was greater than 120 when the mass ratio was 1:20–13:1, showing a good synergistic effect. When the mass ratio of compound (I) to thiamethoxam was 1:35–18:1, the co-toxicity coefficient was greater than 120, showing a synergistic effect.

[0204] Table 1 shows the toxicity test results of compound (I) and flufenoxuron in different ratios against thrips.

[0205]

[0206] Table 2 shows the toxicity test results of compound (I) and flupyradifurone in different ratios against thrips.

[0207]

[0208] Table 3 shows the toxicity test results of compound (I) and thiamethoxam in different ratios against thrips.

[0209]

[0210] 2) Co-toxicity of mixed pairs against rice planthoppers:

[0211] Tables 4-9 show the LC50 results of compound (I) against rice planthopper. 50The concentration was 4.6868 mg / L. Compound (I) exhibited good synergistic effects with rice planthoppers when mixed with flonicamid, fipronil, thiamethoxam, thiamethoxam, dinotefuran, and acetamiprid. Specifically, when the mass ratio of compound (I) to flonicamid was 1:20–15:1, the co-toxicity coefficient was greater than 120, indicating a synergistic effect; when the mass ratio of compound (I) to fipronil was 1:25–15:1, the co-toxicity coefficient was greater than 120, indicating a synergistic effect; when the mass ratio of compound (I) to thiamethoxam was 1:26–18:1, the co-toxicity coefficient was greater than 80, indicating an additive or synergistic effect; among these, the 1:15–18:1 ratio showed a synergistic effect. When the co-toxicity coefficient is greater than 120, it exhibits a synergistic effect; when the mass ratio of compound (I) to thiamethoxam is 1:24 to 12:1, the co-toxicity coefficient is greater than 120, exhibiting a synergistic effect; when the mass ratio of compound (I) to dinotefuran is 1:24 to 15:1, the co-toxicity coefficient is greater than 120, exhibiting a synergistic effect; when the mass ratio of compound (I) to acetamiprid is 1:22 to 16:1, the co-toxicity coefficient is greater than 120, exhibiting a synergistic effect.

[0212] Table 4 shows the toxicity test results of compound (I) and different ratios of flonicamid against rice planthopper.

[0213]

[0214]

[0215] Table 5 shows the toxicity test results of compound (I) and flufenoxuron in different ratios against rice planthoppers.

[0216]

[0217] Table 6 shows the toxicity test results of compound (I) and thiamethoxam in different ratios against rice planthoppers.

[0218]

[0219] Table 7 shows the toxicity test results of compound (I) and thiamethoxam in different ratios against rice planthoppers.

[0220]

[0221]

[0222] Table 8 shows the toxicity test results of compound (I) and different ratios of fipronil against rice planthoppers.

[0223]

[0224] Table 9 shows the toxicity test results of compound (I) and acetamiprid in different ratios against rice planthoppers.

[0225]

[0226] 3) Co-virulence of mixed pairs against whiteflies:

[0227] Tables 10 and 11 show the LC50 of compound (I) against whiteflies. 50 The concentration was 2.3935 mg / L. Compound (I) exhibited good synergistic effects when mixed with flonicamid and flupyrflufenoxam in whiteflies. Specifically, when the mass ratio of compound (I) to flonicamid was 1:36–20:1, the co-toxicity coefficient was greater than 80, showing an additive or synergistic effect; when the mass ratio was 1:24–30:1, the co-toxicity coefficient was greater than 120, showing a synergistic effect; and when the mass ratio of compound (I) to flupyrflufenoxam was 1:24–10:1, the co-toxicity coefficient was greater than 120, showing a synergistic effect.

[0228] Table 10 shows the toxicity test results of compound (I) and flupyradifurone in different ratios against whiteflies.

[0229]

[0230]

[0231] Table 11 shows the toxicity test results of compound (I) and flupyrrolidone in different ratios against whiteflies.

[0232]

[0233] 4) Co-virulence of mixed pairs of cotton aphids:

[0234] Tables 12 and 13 show the LC50 of compound (I) against cotton aphids. 50 The concentration was 88.6755 mg / L. Compound (I) exhibited good synergistic effects with cotton aphids when mixed with acetamiprid and imidacloprid. Specifically, the co-toxicity coefficient was greater than 120 when the mass ratio of compound (I) to acetamiprid was 1:15 to 40:1, demonstrating a synergistic effect; the co-toxicity coefficient was also greater than 120 when the ratio of compound (I) to imidacloprid was 1:20 to 30:1, also demonstrating a synergistic effect.

[0235] Table 12 shows the toxicity test results of compound (I) and different ratios of acetamiprid against cotton aphid.

[0236]

[0237]

[0238] Table 13 shows the toxicity test results of compound (I) and imidacloprid in different ratios against cotton aphids.

[0239]

[0240] 5) Co-toxicity of mixed pairs against diamondback moth:

[0241] Table 14 shows the LC50 results of compound (I) against diamondback moth. 50 The concentration was 0.0374 mg / L. Compound (I) and acetamiprid showed good synergistic effects when mixed. Among them, the co-toxicity coefficient of compound (I) and acetamiprid was greater than 120 when the mass ratio of compound (I) to acetamiprid was 1:25 to 10:1, which showed a synergistic effect.

[0242] Table 14 shows the toxicity test results of compound (I) and different ratios of acetamiprid to diamondback moth.

[0243]

[0244] Example 16

[0245] Field efficacy examples

[0246] Field Trial 1

[0247] Experimental crops and targets: Leeks (Dajingou), tobacco thrips;

[0248] Experiment location: Pingdu leek planting base, Qingdao City, Shandong Province;

[0249] Application equipment: 3WBS16 backpack electric sprayer, with a spray volume of 30L / mu;

[0250] Test date: May 10, 2022;

[0251] Experimental environment: The cultivation conditions in all experimental plots were uniform and the same level of fertilizer and water management was used;

[0252] Test reagents:

[0253] Table 15 Field Trial Design and Pesticide Dosage

[0254]

[0255] Experimental method: Apply the pesticide once during the peak period of thrips infestation.

[0256] Cell size and duplication: randomized block arrangement, 25m per cell 2 Each treatment was repeated 4 times.

[0257] Survey method: Five random sampling points were taken in each plot, with 10 plants fixed at each point. The number of adult and nymph insects on all leaves was investigated. The initial insect population was investigated before the pesticide was applied, and the number of residual insects was investigated 1 day and 7 days after the pesticide was applied.

[0258] Calculation formulas and data analysis:

[0259]

[0260]

[0261] Results of field efficacy trials:

[0262] Table 16 shows the field control efficacy of various pesticides against thrips in leek fields. As can be seen from the table, 1 day after application, 40% compound (I)·thiamethoxam wettable powder (5:35), 25% compound (I)·flufenican suspension (5:20), and 28% compound (I)·flufenican suspension (21:7) showed good rapid efficacy, with control efficacies of 82.46%, 87.25%, and 83.62%, respectively. 7 days after application, all mixed formulations also showed good residual efficacy, with control efficacies above 90%, significantly higher than their control single agents.

[0263] Table 16 Field control effects of different pesticides

[0264]

[0265] Note: The above efficacy data are the average of 4 repetitions, and the values ​​are rounded to two decimal places.

[0266] Safety: During the trial period and later observations, the chives grew normally and no obvious phytotoxicity was observed.

[0267] Field Trial 2

[0268] Experimental crops and targets: rice (Y Liangyou 2), rice planthopper;

[0269] Experimental location: Rice paddies in Jimo, Qingdao City, Shandong Province;

[0270] Application equipment: 3WBS16 backpack electric sprayer. First, spray the control plot with water, then spray the experimental pesticide plot. When spraying, point the nozzle downwards and spray the pesticide solution as close to the base of the rice stem as possible.

[0271] Test date: July 26, 2022;

[0272] Experimental environment: The cultivation conditions of all experimental plots were uniform and the same level of fertilizer and water management was used. The rice grew well and no agricultural operations such as fertilization and irrigation were carried out during the experiment.

[0273] Test reagents:

[0274] Table 17 Field Trial Design and Pesticide Dosage

[0275]

[0276]

[0277] Cell size and duplication: randomized block arrangement, 25m per cell2 Each treatment was repeated 4 times.

[0278] Survey method: Five random sampling points were taken in each plot, with two clumps at each point. A 20×33cm white porcelain plate was used as the carrier, with a small amount of water in the plate. The rice clumps were tapped 4 times each time, and the number of planthoppers in the plate was counted. The number of residual insects in each plot was investigated 1 day and 10 days after the treatment.

[0279] Calculation formulas and data analysis:

[0280]

[0281]

[0282] Results of field efficacy trials:

[0283] Table 18 shows the field control effects of various pesticides on rice planthoppers in paddy fields. The table indicates that, one day after application, the pesticides most effective against planthoppers were: 25% Compound (I)·Flufenamic acid suspension (5:20), 50% Compound (I)·Flufenamic acid nitrile water-dispersible granules (10:40), 60% Compound (I)·Thiamethoxam water-dispersible granules (12:48), 36% Compound (I)·Dinotefuran wettable powder (14:22), and 60%… Compound (I)·acetamiprid wettable powder (24:36) and 19% compound (I)·flupyrrolidone suspension (4:15) showed good rapid efficacy, with control efficacies of 82.09%, 80.32%, 81.75%, 82.46%, 83.11%, and 82.19%, respectively. Seven days after application, the mixed formulations also showed good sustained efficacy, with control efficacies of over 90%, significantly higher than their control single-agent formulations.

[0284] Table 18 Field Trial Design and Dosage

[0285]

[0286]

[0287] Note: The above efficacy data are the average of 4 repetitions, and the values ​​are rounded to two decimal places.

[0288] Safety: Observations showed that the experimental pesticide treatment did not cause phytotoxicity or other adverse effects on rice compared with the blank control area.

[0289] Field Trial 3

[0290] Experimental crops and targets: cucumber (with dense spines), aphids;

[0291] Experimental location: Vegetable greenhouse in Qingzhou, Weifang City, Shandong Province;

[0292] Application equipment: 3WBS16 backpack electric sprayer;

[0293] Test date: June 15, 2022;

[0294] Experimental environment: The cultivation conditions in all experimental plots were uniform and the same level of fertilizer and water management was used;

[0295] Test reagents:

[0296] Table 19 Field Trial Design and Pesticide Dosage

[0297]

[0298] Experimental method: Apply pesticide once during the peak period of aphid infestation.

[0299] Plot size and replication: randomized block design, 2 columns of cucumbers (30 plants) per plot, 4 replicates per treatment.

[0300] Survey method: Five random sampling points were taken in each plot, with one plant fixed at each point. The number of aphids on all leaves of the whole plant was investigated. The initial insect population was investigated before the pesticide was applied, and the number of residual insects was investigated 1 day and 5 days after the pesticide was applied.

[0301] Calculation formulas and data analysis:

[0302]

[0303]

[0304] Results of field efficacy trials:

[0305] Table 20 shows the field control efficacy of various pesticides against cucumber aphids. As can be seen from the table, 1 day after application, 54% compound (I)·acetamiprid water-dispersible granules (48:6) and 45% compound (I)·imidacloprid water-dispersible granules (35:10) showed good rapid efficacy, with control efficacies of 82.35% and 84.11%, respectively. 5 days after application, the mixed formulations also showed good residual efficacy, with control efficacies of 89.37% and 90.06%, respectively, significantly higher than their control single agents.

[0306] Table 20 Field control effects of different pesticides

[0307]

[0308] Note: The above efficacy data are the average of 4 repetitions, and the values ​​are rounded to two decimal places.

[0309] Safety: During and after the trial period, the cucumbers grew normally and no obvious phytotoxicity was observed.

[0310] The pesticide compositions or formulations obtained by this invention exhibit significant preventative efficacy, demonstrating superior performance compared to single-agent formulations in delaying the development of resistance and prolonging pesticide retention. Furthermore, no phytotoxicity was observed in the experiments with the compounded pesticides, indicating that the enhanced synergistic insecticidal effect of the resulting pesticide compositions or formulations can reduce production and usage costs while ensuring crop safety.

[0311] Although the present invention has been described in detail above with general description and specific embodiments, some modifications or improvements can be made to it based on the present invention, which will be obvious to those skilled in the art. Therefore, all such modifications or improvements made without departing from the spirit of the present invention are within the scope of protection claimed by the present invention.

Claims

1. A neonicotinoid-containing pesticidal composition, characterized by: comprising active ingredient A and active ingredient B, said active ingredient A being a compound of formula (I) , The active ingredient B is a neonicotinoid compound, and the neonicotinoid compound is flonicamid, sulfoxaflor, clothianidin, thiamethoxam, acetamiprid, thiacloprid, imidacloprid, dinotefuran, nitenpyram, flupyradifurone. The mass ratio of the compound of formula (I) to flonicamid is 1:27-15:1; the mass ratio of the compound of formula (I) to sulfoxaflor is 1:24-20:1; the mass ratio of the compound of formula (I) to clothianidin is 1:15-18:1; the mass ratio of the compound of formula (I) to thiamethoxam is 1:35-18:1; the mass ratio of the compound of formula (I) to acetamiprid is 1:25-40:1; the mass ratio of the compound of formula (I) to thiacloprid is 1:24-12:1; the mass ratio of the compound of formula (I) to imidacloprid is 1:20-30:1; the mass ratio of the compound of formula (I) to dinotefuran is 1:24-15:1; the mass ratio of the compound of formula (I) to nitenpyram is 1:22-16:1; and the mass ratio of the compound of formula (I) to flupyradifurone is 1:24-10:

1.

2. The pesticidal composition according to claim 1, characterized in that: The total content of the active ingredient A and the active ingredient B in the pesticide composition is 0.5%-90% based on 100wt% of the total mass of the pesticide composition.

3. The pesticidal composition according to claim 2, characterized in that: The total content of the active ingredient A and the active ingredient B in the pesticide composition is 1%-85% based on 100wt% of the total mass of the pesticide composition.

4. The pesticidal composition according to claim 1, characterized in that: The pesticide composition further comprises an agriculturally acceptable auxiliary ingredient in addition to the active ingredients, and the auxiliary ingredient is selected from one or more of wetting agents, dispersants, emulsifiers, thickening agents, disintegrants, antifreezing agents, antifoaming agents, solvents, preservatives, stabilizers, synergists or carriers.

5. The pesticidal composition according to claim 4, characterized in that: The pesticide composition can be prepared into an agriculturally permissible formulation form, and the formulation form is selected from solid formulations and / or liquid formulations; the solid formulation is selected from wettable powders and water dispersible granules; and the liquid formulation is selected from emulsifiable concentrates, water emulsions, microemulsions, suspensions, suspoemulsions and dispersible oil suspensions.

6. The use of the pesticide composition according to any one of claims 1 to 5 for controlling agricultural and forestry pests, sanitary pests, characterized in that, The agricultural and forestry pests, and the sanitary pests are thrips, planthoppers, whiteflies, aphids and diamondback moths.

7. Use according to claim 6, characterized in that: The pesticide composition is applied to pests in need of control or a medium where pests grow in an effective dose.

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