Water maze device and method for detecting cognitive function of rats with vascular cognitive impairment

Abstract

The invention relates to a water maze device and method for detecting cognitive function of rats with vascular cognitive impairment, comprising a mounting sleeve, a bracket being arranged on the mounting sleeve, a crossbeam being arranged on the bracket; an upper light source assembly and a lower capture net being longitudinally distributed are arranged on the crossbeam, a vertical pole being fixed at the center of the lower capture net; the upper light source assembly comprises a reflector, a sleeve, an even number of light bars and a deflection unit, and a water-absorbing cotton strip is arranged on the side surface of the light bar; the vertical pole passes through the sleeve, a height adjustment assembly is arranged on the crossbeam, and the height adjustment assembly can adjust the height of the upper light source assembly and the height of the lower capture net respectively; rats can be put in from any position beside a pool, and can be put in multiple times from a single position, and the capture success rate of rats after the experiment is very high, the capture speed is fast, and water draining, water absorption and preliminary drying operations are performed during the capture process, so that the rats can be quickly dried after entering and leaving a pipeline, thereby solving the problems encountered in the current water maze.

Description

Technical Field

[0001] The present invention relates to the technical field of cognitive function detection, and more specifically to a water maze device and method for detecting cognitive function of rats with vascular cognitive impairment. Background Art

[0002] The Morris water maze is an important tool for studying spatial memory and learning. The task requires experimental animals to find a hidden platform in a pool filled with opaque water that has been dyed with titanium dioxide or non-toxic pigments. Animals cannot see or smell the platform, so they must rely on clues in the environment; with experience, animals will locate the platform faster and faster; since Richard G. Morris invented this experiment in 1984, it has become one of the standard tests in behavioral neuroscience.

[0003] The problem with the existing water maze device is that the staff has to release rats with great intensity, and after each rat training, the staff is required to catch the rats from the platform, take them away for drying or other observation. When the staff catch the rats, it is easy for the rats to escape from the platform into the water and cannot be caught. The staff has a high labor intensity to catch the rats, and it is also easy to cause unexpected situations to interfere with the experiment.

[0004] The Chinese application, application number CN202011345211.0, provides a fully automatic intelligent water maze experimental device, which captures rats by means of a capture net with an infrared probe. A plurality of storage chambers surrounding the pool are designed for releasing the rats. The rats are released by opening the storage chambers and dried by infrared electric lamps. However, this device still has major defects: 1. The infrared probe positioning capture itself has a certain delay. If the rat is in a moving state or flees due to the stimulation of the approaching capture net, the capture will fail, which makes the capture success rate of the equipment extremely low; 2. There are cases where the rats in the storage room do not jump into the pool, so that the experimental device cannot run normally and automatically, and only one rat can be released at a single location in one experiment; 3. When drying rats with a single infrared electric lamp, it is easy for one side of the rat to be dried but the other side is not dried, and it is difficult to achieve the expected drying effect; a more efficient and stable water maze device and method for detecting the cognitive function of rats with vascular cognitive impairment is needed. Summary of the invention

[0005] The technical problem to be solved by the present invention is to provide a water maze device for detecting cognitive function of rats with vascular cognitive impairment, and also provide a method for detecting cognitive function of rats with vascular cognitive impairment, in view of the above-mentioned defects of the prior art.

[0006] The technical solution adopted by the present invention to solve the technical problem is:

[0007] A water maze device for detecting cognitive function of rats with vascular cognitive impairment is constructed, comprising a circular pool, wherein a platform for cognitive training is arranged in the pool, wherein the device further comprises a circular mounting sleeve mounted outside the pool, wherein a bracket is arranged on the mounting sleeve, wherein a crossbeam extending to directly above the pool is arranged on the bracket; an upper light source assembly and a lower capture net distributed longitudinally are arranged on the crossbeam, wherein the size of the lower capture net is equivalent to the size of the internal space of the pool; an opening corresponding to the platform is arranged on the lower capture net, wherein a circular elastic cloth piece is arranged at the opening; a vertical pole is detachably connected to the center of the lower capture net, wherein an electromagnet is arranged at the lower end of the vertical pole; the upper light source assembly comprises a reflector, a sleeve fixed through the center of the reflector, an even number of light strips arranged around the sleeve, and a plurality of light strips driving the light strips. The light strips on all odd-numbered positions in the strip are swung around the sleeve by a swing unit, and a water-absorbing cotton strip is arranged on the side surface of the light strip; the reflective surface of the reflector faces downward, and the light emitting direction of the light strip is toward the reflective surface of the reflector; the vertical pole passes through the sleeve, and a height adjustment component is arranged on the crossbeam, and the height adjustment component can adjust the height of the upper light source component and the height of the lower capture net respectively; the mounting sleeve is provided with a plurality of transparent tubes for storing rats inclined downward, a departure pipe for rats to leave, and a rotating unit for driving the plurality of transparent tubes and the departure pipe to rotate around the edge of the pool, and the departure pipe is provided with an infrared probe for detecting rats; a drying head for discharging hot air is arranged around the departure pipe, an electric door is arranged at the lower end of the transparent tube and is located at the edge of the pool, and a plurality of transparent tubes are distributed around the pool.

[0008] The water maze device for detecting cognitive function of rats with vascular cognitive impairment described in the present invention comprises: an annular swivel is rotatably provided on the mounting sleeve, an outer gear ring is provided on the outer surface of the swivel; a servo motor is provided on the mounting sleeve, a driving gear meshing with the outer gear ring is provided at the active end of the servo motor; and the transparent tube and the exit pipe are both passed through the swivel.

[0009] The water maze device for detecting cognitive function of rats with vascular cognitive impairment described in the present invention is characterized in that electric-controlled doors are provided at both ends of the exit pipe, and a buffer tube is connected to the tail end of the exit pipe; a collecting box with an upper opening is fixed outside the mounting sleeve, and the moving trajectory of the buffer tube passes directly above the collecting box.

[0010] The water maze device for detecting cognitive function of rats with vascular cognitive impairment described in the present invention, wherein the outer surface of the exit pipe is fixed with a multi-way pipe connected to a plurality of the drying heads, a fan for intake of air to the multi-way pipe, and an air collecting hood located on the air intake side of the fan, wherein a heating wire unit for heating the intake air is arranged in the air collecting hood.

[0011] The water maze device for detecting cognitive function of rats with vascular cognitive impairment described in the present invention, wherein the height adjustment component includes a first electric push rod installed on the crossbeam to drive the vertical rod to rise and fall, and a second electric push rod installed on the crossbeam to drive the sleeve to rise and fall.

[0012] The water maze device for detecting cognitive function of rats with vascular cognitive impairment described in the present invention, wherein the deflection unit includes a rotating seat coaxially connected to the lower end of the sleeve, and the rotating seat is provided with a plurality of connecting plates connected to the light strips on the odd-numbered positions in a one-to-one correspondence; a micro motor is fixed to the light strip on any even-numbered position, and the micro motor drives the rotating seat to rotate through a reduction gear.

[0013] The water maze device for detecting cognitive function of rats with vascular cognitive impairment of the present invention comprises the following steps: the outer edge of the elastic cloth piece is connected to the edge of the opening, and the inner edge of the elastic cloth piece is sutured and connected with a circular rubber band.

[0014] A method for detecting cognitive function of rats with vascular cognitive impairment, using the water maze device for detecting cognitive function of rats with vascular cognitive impairment as described above, wherein the method comprises the following steps:

[0015] Before the experiment begins, the lower capture net is lowered and submerged in the water of the pool through the height adjustment component, the platform passes through the opening, the electromagnet is powered off, the vertical pole is removed, and the lighting height of the upper light source component is adjusted and recorded through the height adjustment component; multiple rats are placed in the transparent tube one by one;

[0016] During the experiment, the following operations were used for the experimental session of a single rat:

[0017] The rotating unit drives multiple transparent tubes to rotate around the edge of the pool until the transparent tube containing the rat is moved to the required placement location, and the electric door is controlled to open. The rat slides down from the transparent tube into the pool by its own weight, and the electric door is controlled to close.

[0018] At the end of the single rat experiment, the upper light source assembly is adjusted to descend to the upper edge of the exit pipe through the height adjustment component, and the lower capture net is adjusted to rise above the water surface and located at the lower edge of the exit pipe through the height adjustment component. At this time, the platform leaves the opening, the elastic cloth piece contracts and closes the opening, and the rat is driven by the lower capture net to leave the water surface, and the water on the rat drips freely; the upper light source assembly is adjusted to descend to the position where the rat is located between the two light strips through the height adjustment component, and the rat is initially dried by the heat of the light strips; the exit pipe is driven to rotate by the rotating unit and the rat is detected by an infrared probe, and the rotation stops after the rat is detected, and a signal is sent to the deflection unit; the operation of the deflection unit drives the light strips on the odd positions to deflect around the casing, and the rat is gradually expelled from the exit pipe. During the expulsion process, the rat is protected against pinching and further absorbed by absorbent cotton strips; the rat entering the exit pipe is dried by a surrounding drying head that emits hot air.

[0019] The beneficial effects of the present invention are as follows: before the experiment begins, the lower capture net is adjusted by the height adjustment component to be lowered and immersed in the water of the pool, the platform passes through the opening, the electromagnet is powered off, the vertical pole is removed, and the lighting height of the upper light source component is adjusted by the height adjustment component and recorded; multiple rats are placed in the transparent tube one by one;

[0020] During the experiment, the following operations were used for the experimental session of a single rat:

[0021] The rotating unit drives multiple transparent tubes to rotate around the edge of the pool until the transparent tube containing the rat is moved to the required placement location, and the electric door is controlled to open. The rat slides down from the transparent tube into the pool by its own weight, and the electric door is controlled to close.

[0022] At the end of the single rat experiment, the upper light source assembly is adjusted to descend to the upper edge of the exit pipe by the height adjustment assembly, and the lower capture net is adjusted to rise above the water surface and located at the lower edge of the exit pipe by the height adjustment assembly. At this time, the platform leaves the opening, the elastic cloth piece contracts and closes the opening, and the rat is driven by the lower capture net to leave the water surface, and the water on the rat drips freely; the upper light source assembly is adjusted to descend to the position where the rat is located between the two light bars by the height adjustment assembly, and the rat is initially dried by the heat of the light bars; the exit pipe is driven to rotate by the rotating unit and the rat is detected by the infrared probe, and the rotation is stopped after the rat is detected, and a signal is sent to the deflection unit; the operation of the deflection unit drives the light bars on the odd positions to deflect around the casing, and the rat is gradually expelled from the exit pipe. During the expulsion process, the rat is protected against pinching and further absorbed by the absorbent cotton strips; the rat entering the exit pipe is dried by the surrounding drying head that emits hot air;

[0023] By using the device of the present application, not only can rats be placed from any position beside the pool, but also they can be placed multiple times from a single position. Moreover, the rat capture success rate after the experiment is very high, the capture speed is fast, and during the capture process, drainage, water absorption and preliminary drying operations are performed, which facilitates the rapid drying of the rats after entering and leaving the pipe, solving the problems encountered in current water mazes. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the present invention will be further described below in conjunction with the accompanying drawings and embodiments. The drawings described below are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative work:

[0025] Figure 1 is a cross-sectional view of a water maze apparatus for detecting cognitive function in rats with vascular cognitive impairment according to a preferred embodiment of the present invention;

[0026] Figure 2 2. It is a bottom view of a light source assembly on a water maze device for detecting cognitive function of rats with vascular cognitive impairment according to a preferred embodiment of the present invention;

[0027] Figure 3 It is a schematic diagram of the fan structure of a water maze device for detecting cognitive function of rats with vascular cognitive impairment according to a preferred embodiment of the present invention. DETAILED DESCRIPTION

[0028] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the following will be described clearly and completely in combination with the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are partial embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work belong to the protection scope of the present invention.

[0029] The water maze device for detecting cognitive function of rats with vascular cognitive impairment in a preferred embodiment of the present invention is as follows: Figure 1 See also Figure 2 and Figure 3, including a circular pool 1, a platform 10 for cognitive training is arranged in the pool 1, and a circular installation sleeve 2 is arranged outside the pool 1, a bracket 3 is arranged on the installation sleeve 2, and a crossbeam 30 extending to the top of the pool 1 is arranged on the bracket 3; when in use, the camera can be configured on the bracket; the crossbeam 30 is provided with a longitudinally distributed upper light source assembly 4 and a lower capture net 5, and the size of the lower capture net 5 is equivalent to the internal space size of the pool 1; the lower capture net 5 is provided with an opening corresponding to the platform 10 50, a circular elastic cloth piece 51 is arranged at the opening 50; a vertical pole 52 is detachably connected at the center of the lower capture net 5, and an electromagnet 520 is arranged at the lower end of the vertical pole 52 (after the lower capture net 5 is placed, the magnetic force of the electromagnet is released and the vertical pole can be removed to avoid interference with the experiment); the upper light source assembly 4 includes a reflector 40, a sleeve 41 fixed at the center of the reflector 40, an even number of light strips 42 arranged around the sleeve 41, and a plurality of light strips 42 on all odd positions of the light strips 42 are driven to go around the sleeve 41. 1 deflection unit 43, a water-absorbing cotton strip 420 is arranged on the side surface of the light bar 42; the reflective surface of the reflector 40 faces downward, and the light direction of the light bar faces the reflective surface of the reflector 40 (the light is provided to the pool by a multi-light bar reflection method to avoid direct radiation, the light is softer, and the impact of water surface reflection is reduced); the vertical pole 52 passes through the sleeve 41, and the crossbeam 30 is provided with a height adjustment component 32, which can adjust the height of the upper light source component 4 and the height of the lower capture net 5 respectively; The housing 2 is provided with a plurality of transparent tubes 20 for storing rats in an oblique downward direction, a departure pipe 21 for rats to leave, and a rotating unit 6 for driving the plurality of transparent tubes 20 (with air holes for ventilation) and the departure pipe 21 (with air holes for ventilation) to rotate around the edge of the pool, and an infrared probe for detecting rats is provided on the departure pipe 21; a drying head 211 for discharging hot air is arranged around the departure pipe 21, an electric door 200 is provided at the lower end of the transparent tube 20 and is located at the edge of the pool, and a plurality of transparent tubes 20 are distributed around the pool;

[0030] Before the experiment begins, the lower capture net 5 is lowered and submerged in the water of the pool 1 by adjusting the height adjustment component 32, the platform 10 passes through the opening, and the lighting height of the upper light source component 4 is adjusted and recorded by the height adjustment component 32; multiple rats are placed in the transparent tube 20 one by one;

[0031] During the experiment, the following operations were used for the experimental session of a single rat:

[0032] The rotating unit 6 drives the plurality of transparent tubes 20 to rotate around the edge of the pool 1 until the transparent tube 20 containing the rat is moved to the desired placement location, and the electric door 200 is controlled to open. The rat slides down from the transparent tube 20 by its own weight and falls into the pool 1, and the electric door 200 is controlled to close.

[0033] At the end of the single rat experiment, the upper light source assembly is adjusted to descend to the upper edge of the exit pipe by the height adjustment assembly, and the lower capture net 5 is adjusted to rise above the water surface and located at the lower edge of the exit pipe 21 by the height adjustment assembly 32. At this time, the platform 10 leaves the opening, the elastic cloth sheet 51 contracts and closes the opening 50, and the rat is driven by the lower capture net 5 to leave the water surface, and the water on the rat drips freely (drainage);

[0034] The upper light source assembly 4 is adjusted by the height adjustment assembly 32 to move downward until the rat is located between the two light bars 42, and the rat is initially dried by the heat generated by the light bars 42;

[0035] The rotating unit 6 drives the exit pipe 21 to rotate and uses an infrared probe to detect rats. After detecting the rats, the rotation stops (at this time, the exit pipe 21 is directly opposite to the position between the two light bars 42 where the rats are located), and a signal is sent to the deflection unit 43; the deflection unit 43 drives the light bars 42 on the odd positions to deflect around the sleeve 41, and gradually drives the rats out of the exit pipe. During the driving process, the rats are protected from being pinched by the absorbent cotton 420 and further absorb water (absorb water) (at this time, it should be noted that a certain safety distance should be left when the light bars 42 move, and they cannot be completely closed, and driving is mainly used); the rats entering the exit pipe 21 are dried (dried) by the surrounding drying head 211 that discharges hot air;

[0036] By using the device of the present application, not only can rats be placed from any position beside the pool (without any position limitation), but also rats can be placed multiple times from a single position. Moreover, the rat capture success rate after the experiment is very high, the capture speed is fast, and the capture process is accompanied by drainage, water absorption and preliminary drying operations, which facilitates the rapid drying of the rats after entering and leaving the pipe, solving the problems encountered in the current water maze.

[0037] Preferably, an annular swivel 60 is rotatably provided on the mounting sleeve 2, and an outer gear ring 600 is provided on the outer surface of the swivel 60; a servo motor 61 is provided on the mounting sleeve 2, and a driving gear 610 meshing with the outer gear ring is provided at the movable end of the servo motor 61; the transparent tube 20 and the exit pipe 21 are both passed through the swivel 60; the swivel 60, the outer gear ring 600, the servo motor 61 and the driving gear 610 are combined to form a rotating unit 6; when setting, it is necessary to pay attention to the gap between the pool 1 and the swivel 60 not being too large, otherwise the rat may escape from the gap.

[0038] Preferably, both ends of the exit pipe 21 are provided with electric control doors 212, and the tail end of the exit pipe 21 is connected with a buffer pipe 213; a collection box 23 with an upper end opening is fixed outside the installation sleeve 2 (which can be fixedly connected to the bracket 3), and the moving track of the buffer pipe 213 passes directly above the collection box 23;

[0039] The purpose of adopting this design is that after drying a rat, the rotating unit 6 can be used to drive the rat out of the pipe 21 to rotate. When the buffer tube 213 reaches above the collection box 23, the electric door 212 on this side is opened, and the drying head 211 blows air to drive the rat into the buffer tube 213, and the rat falls into the collection box 23 from the buffer tube 213, thereby solving the problem that the rat cannot be automatically collected after drying. Some buffer sheets can be set in the buffer tube 213 for buffering.

[0040] Preferably, a multi-way pipe 214 connecting multiple drying heads 211, a fan 215 for supplying air to the multi-way pipe 214, and an air collecting hood 216 located on the air inlet side of the fan are fixed to the outer surface of the pipe 21, and a heating wire unit 217 for heating the intake air is arranged in the air collecting hood 216; the structure is simple, the assembly is convenient, and the cost is low.

[0041] Preferably, the height adjustment assembly 32 includes a first electric push rod 320 installed on the crossbeam 30 to drive the vertical pole to rise and fall, and a second electric push rod 321 installed on the crossbeam to drive the sleeve to rise and fall; the structure is simple, the assembly is convenient, and the cost is low.

[0042] Preferably, the deflection unit 43 includes a rotating seat 430 coaxially connected to the lower end of the sleeve 41, and the rotating seat 430 is provided with a plurality of connecting plates 431 correspondingly connected to the light strips 42 on the odd positions; a micro motor 432 is fixed on the light strip 42 on any even position, and the micro motor 432 drives the rotating seat 430 (a gear ring is provided on the outer surface of the rotating seat) to rotate through a reduction gear 433; the drive control is convenient, the structure is simple, and the cost is low.

[0043] Preferably, the outer edge of the elastic cloth piece 51 is connected to the edge of the opening, and the inner edge of the elastic cloth piece 51 is sewn with a ring-shaped rubber band; the elastic deformation ability of the elastic cloth piece 51 itself and the elasticity of the rubber band are relied upon to avoid the platform 10.

[0044] A method for detecting cognitive function of rats with vascular cognitive impairment, using the water maze device for detecting cognitive function of rats with vascular cognitive impairment as described above, wherein the method comprises the following steps:

[0045] Before the experiment begins, the lower capture net is lowered and submerged in the water of the pool through the height adjustment component, the platform passes through the opening, the electromagnet is powered off, the vertical pole is removed, and the lighting height of the upper light source component is adjusted and recorded through the height adjustment component; multiple rats are placed in the transparent tube one by one;

[0046] During the experiment, the following operations were used for the experimental session of a single rat:

[0047] The rotating unit drives multiple transparent tubes to rotate around the edge of the pool until the transparent tube containing the rat is moved to the required placement location, and the electric door is controlled to open. The rat slides down from the transparent tube into the pool by its own weight, and the electric door is controlled to close.

[0048] At the end of the single rat experiment, the upper light source assembly is adjusted to descend to the upper edge of the exit pipe through the height adjustment component, and the lower capture net is adjusted to rise above the water surface and located at the lower edge of the exit pipe through the height adjustment component. At this time, the platform leaves the opening, the elastic cloth piece contracts and closes the opening, and the rat is driven by the lower capture net to leave the water surface, and the water on the rat drips freely; the upper light source assembly is adjusted to descend to the position where the rat is located between the two light strips through the height adjustment component, and the rat is initially dried by the heat of the light strips; the exit pipe is driven to rotate by the rotating unit and the rat is detected by an infrared probe, and the rotation stops after the rat is detected, and a signal is sent to the deflection unit; the operation of the deflection unit drives the light strips on the odd positions to deflect around the casing, and the rat is gradually expelled from the exit pipe. During the expulsion process, the rat is protected against pinching and further absorbed by absorbent cotton strips; the rat entering the exit pipe is dried by a surrounding drying head that emits hot air.

[0049] By using the method of the present application, not only can rats be placed from any position beside the pool, but also they can be placed multiple times from a single position. Moreover, the rat capture success rate after the experiment is very high, the capture speed is fast, and during the capture process, drainage, water absorption and preliminary drying operations are performed, which facilitates rapid drying of the rats after entering and leaving the pipe, solving the problems encountered in current water mazes.

[0050] It should be understood that those skilled in the art can make improvements or changes based on the above description, and all these improvements and changes should fall within the scope of protection of the appended claims of the present invention.

Claims

1. A water maze device for detecting cognitive function of rats with vascular cognitive impairment, comprising a circular pool, wherein a platform for cognitive training is arranged in the pool, characterized in that: It also includes a circular installation sleeve that is sleeved outside the pool, the installation sleeve is provided with a bracket, the bracket is provided with a crossbeam extending to the top of the pool; the crossbeam is provided with a longitudinally distributed upper light source assembly and a lower capture net, the size of the lower capture net is equivalent to the internal space size of the pool; the lower capture net is provided with an opening corresponding to the platform, and a circular elastic cloth piece is provided at the opening; the center of the lower capture net is detachably connected to a vertical pole, and the lower end of the vertical pole is provided with an electromagnet; the upper light source assembly includes a reflector, a sleeve that is passed through and fixed at the center of the reflector, an even number of light strips arranged around the sleeve, and a swing unit that drives all odd-numbered light strips among the multiple light strips to swing around the sleeve, and the light strips A water-absorbing cotton strip is arranged on the side surface; the reflective surface of the reflective board faces downward, and the light-emitting direction of the light strip is toward the reflective surface of the reflective board; the vertical pole passes through the sleeve, and the crossbeam is provided with a height adjustment component, and the height adjustment component can adjust the height of the upper light source component and the height of the lower capture net respectively; the mounting sleeve is provided with a plurality of transparent tubes for storing rats obliquely downward, an exit pipe for rats to leave, and a rotating unit for driving the plurality of transparent tubes and the exit pipe to rotate around the edge of the pool, and the exit pipe is provided with an infrared probe for detecting rats; a drying head for discharging hot air is arranged around the exit pipe, an electric door is provided at the lower end of the transparent tube and is located at the edge of the pool, and a plurality of the transparent tubes are distributed around the pool.

2. The water maze device for detecting cognitive function of rats with vascular cognitive impairment according to claim 1, characterized in that: The mounting sleeve is provided with an annular swivel for rotation, and an outer gear ring is provided on the outer surface of the swivel; the mounting sleeve is provided with a servo motor, and a driving gear meshing with the outer gear ring is provided at the movable end of the servo motor; the transparent tube and the exit pipe are both passed through the swivel.

3. The water maze device for detecting cognitive function of rats with vascular cognitive impairment according to claim 2, characterized in that: Both ends of the exit pipe are provided with electric control doors, and the tail end of the exit pipe is connected with a buffer tube; a collection box with an upper opening is fixed outside the installation sleeve, and the moving track of the buffer tube passes directly above the collection box.

4. The water maze device for detecting cognitive function of rats with vascular cognitive impairment according to claim 3, characterized in that: A multi-way pipe connecting a plurality of drying heads, a fan for supplying air to the multi-way pipe, and an air collecting hood located on the air inlet side of the fan are fixed on the outer surface of the exit pipe, and a heating wire unit for heating the intake air is arranged in the air collecting hood.

5. The water maze device for detecting cognitive function of rats with vascular cognitive impairment according to claim 1, characterized in that: The height adjustment assembly includes a first electric push rod installed on the crossbeam to drive the vertical pole to rise and fall, and a second electric push rod installed on the crossbeam to drive the sleeve to rise and fall.

6. The water maze device for detecting cognitive function of rats with vascular cognitive impairment according to claim 1, characterized in that: The deflection unit includes a rotating seat coaxially connected to the lower end of the sleeve, and the rotating seat is provided with a plurality of connecting plates connected to the light strips on the odd positions in a one-to-one correspondence; a micro motor is fixed to the light strip on any even position, and the micro motor drives the rotating seat to rotate through a reduction gear.

7. The water maze device for detecting cognitive function of rats with vascular cognitive impairment according to claim 1, characterized in that: The outer edge of the elastic cloth piece is connected to the edge of the opening, and the inner edge of the elastic cloth piece is sewn and connected with a ring-shaped rubber band.

8. A method for detecting cognitive function in rats with vascular cognitive impairment, using the water maze device for detecting cognitive function in rats with vascular cognitive impairment as described in any one of claims 1 to 7, characterized in that: The method comprises the following steps: Before the experiment begins, the lower capture net is lowered and submerged in the water of the pool through the height adjustment component, the platform passes through the opening, the electromagnet is powered off, the vertical pole is removed, and the lighting height of the upper light source component is adjusted and recorded through the height adjustment component; multiple rats are placed in the transparent tube one by one; During the experiment, the following operations were used for the experimental session of a single rat: The rotating unit drives multiple transparent tubes to rotate around the edge of the pool until the transparent tube containing the rat is moved to the required placement location, and the electric door is controlled to open. The rat slides down from the transparent tube into the pool by its own weight, and the electric door is controlled to close. At the end of the single rat experiment, the upper light source assembly is adjusted to descend to the upper edge of the exit pipe through the height adjustment component, and the lower capture net is adjusted to rise above the water surface and located at the lower edge of the exit pipe through the height adjustment component. At this time, the platform leaves the opening, the elastic cloth piece contracts and closes the opening, and the rat is driven by the lower capture net to leave the water surface, and the water on the rat drips freely; the upper light source assembly is adjusted to descend to the position where the rat is located between the two light strips through the height adjustment component, and the rat is initially dried by the heat of the light strips; the exit pipe is driven to rotate by the rotating unit and the rat is detected by an infrared probe, and the rotation stops after the rat is detected, and a signal is sent to the deflection unit; the operation of the deflection unit drives the light strips on the odd positions to deflect around the casing, and the rat is gradually expelled from the exit pipe. During the expulsion process, the rat is protected against pinching and further absorbed by absorbent cotton strips; the rat entering the exit pipe is dried by a surrounding drying head that emits hot air.

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