Cerebrospinal fluid drainage device and drainage system

Abstract

The application discloses a cerebrospinal fluid drainage device and a drainage system. The drainage device comprises a drainage component having a drainage cavity, a sink groove formed on the outer periphery of the drainage component and radially inwardly contracted, a drainage hole arranged on the groove bottom of the sink groove to make the drainage cavity communicate with the sink groove, a disturbance component comprising a disturbance rod and radially extending bristles arranged on the disturbance rod, the disturbance rod extending into the drainage cavity from the proximal end of the drainage component, the bristles corresponding to the drainage hole, and the distal end of the bristles being capable of extending to the radial outside of the groove bottom of the sink groove through the drainage hole, the bristles disturbing the drainage hole by being driven, and a converging component connected to the proximal end of the drainage component, the converging component having a converging cavity, the converging cavity communicating with the drainage cavity.

Description

TECHNICAL FIELD

[0001] The present application relates to an apparatus for transferring body fluid from a human body, and in particular to a cerebrospinal fluid drainage device and a drainage system. BACKGROUND

[0002] Intracranial injury, brain tissue self-disease (such as brain tumor, cerebral hemorrhage, encephalitis, cerebrospinal fluid metabolism abnormality), intracranial surgery, etc. may cause excessive production of cerebrospinal fluid. Excessive cerebrospinal fluid may cause intracranial pressure to rise significantly on the one hand, and may cause brain tissue to expand on the other hand, thus causing extrusion of brain tissue, resulting in local and overall displacement, deformation, secondary damage of brain tissue, and further causing dysfunction of patients, and even death.

[0003] Cerebrospinal fluid drainage (shunt) is a treatment method for transferring intracranial cerebrospinal fluid to a body cavity (such as an abdominal cavity) of the body in order to restore the balance between cerebrospinal fluid secretion and absorption and to reduce intracranial pressure to a reasonable level. A drainage system for performing drainage generally includes a rod-shaped (tubular) drainage component for intruding into brain tissue in the skull, a drainage tube connected to the drainage component at a distal end and intruding into a body cavity (such as an abdominal cavity) of a patient at a proximal end, and a drainage control module provided on the drainage tube for controlling the flow and flow rate of cerebrospinal fluid. In the prior art, the drainage component is configured in the following structure: the drainage component has a drainage cavity therein, and a plurality of drainage holes are formed in the wall of the drainage component and penetrate the drainage cavity. During the implementation of drainage, cerebrospinal fluid enters the drainage cavity through the drainage holes and is then guided out of the drainage cavity.

[0004] A typical problem in the implementation of drainage of cerebrospinal fluid by using the above-described drainage component is that some substances (such as protein particles) in the cerebrospinal fluid may accumulate at the drainage holes to block the drainage holes, especially during a long-time drainage process, the degree and probability of blockage of the drainage holes significantly increase, thus resulting in increased drainage resistance and reduced drainage effect.

[0005] To solve the above problem, the prior art provides a drainage device as shown in FIG. 1, which is additionally provided with a disturbance rod 3000 having bristles 3001. Specifically, the disturbance rod 3000 extends into the drainage cavity of a drainage component 2000 (which intrudes into brain tissue 1000), and the bristles 3001 on the disturbance rod 3000 correspondingly extend into the drainage holes 2001. By driving the disturbance rod 3000 as a whole or by applying mechanical energy to each bristle 3001, the bristles 3001 are disturbed in the drainage holes 2001 to prevent the accumulation of substances such as protein particles and to destroy the accumulated substances, thereby preventing the drainage holes from being blocked to a certain extent. Figure 1

[0006] ​However, the drainage device with the disturbance rod with the bristles still has the following defects in preventing the drainage hole from being blocked:

[0007] 1. When the bristles are arranged, the distal end of the bristles cannot extend out of the outer port of the drainage hole, that is, cannot extend out of the outer circumferential surface of the rod-shaped drainage member, and the reason is that in many cases, the brain tissue is in a state of being very close to or even in contact with the outer circumferential surface of the drainage member, and if the distal end of the bristles extends out of the outer circumferential surface, the disturbance of the bristles can damage the brain tissue cells, and thus it is necessary to limit the distal end of the bristles within the outer port of the drainage hole. However, such an arrangement results in the following consequences: the disturbance of the bristles cannot prevent the substances in the cerebrospinal fluid from accumulating at the outer port of the drainage hole, and the disturbance of the bristles cannot destroy the substances that have accumulated at the outer port.

[0008] 2. In many cases, at least part of the outer circumferential surface of the drainage member is in contact with the brain tissue (the contact can be formed when the drainage member invades the brain tissue, or can be formed due to the growth of the brain tissue after long-term drainage), and the brain tissue blocks the drainage hole due to the contact with the outer circumferential surface of the drainage member.

[0009] In addition, generally, during the drainage of the cerebrospinal fluid, it is also necessary to deliver drugs (such as mannitol) to the brain tissue, and in the prior art, the drugs are generally delivered by intravenous injection. However, due to the blood-brain barrier in the human body, only a small amount of the drugs can act on the brain tissue, and thus the treatment effect of delivering the drugs to the brain tissue by intravenous injection is poor. SUMMARY

[0010] In view of the above technical problems in the prior art, embodiments of the present application provide a cerebrospinal fluid drainage device and a drainage system.

[0011] To solve the above technical problems, the technical scheme adopted by the embodiments of the present application is as follows:

[0012] A cerebrospinal fluid drainage device, comprising:

[0013] a rod-shaped drainage member, the drainage member has an axially extending drainage cavity therein, and a plurality of radially inwardly tapered grooves are arranged in a circumferential direction on the outer circumferential surface of the drainage member and axially extend, the width of the groove opening of each groove in the circumferential direction is smaller than the width of the groove bottom in the circumferential direction, and the plurality of grooves divide the drainage member into a plurality of main walls arranged in a circumferential direction; and the outer surfaces of the plurality of main walls envelope a cylindrical surface;

[0014] a drainage hole is formed in the groove bottom of the groove so that the drainage cavity and the groove are in communication;

[0015] a disturbing component comprising a disturbing rod and radially extending bristles arranged on the disturbing rod, the disturbing rod extends into the drainage cavity from the proximal end of the drainage component, and the bristles correspond to the drainage holes, and the distal end of the bristles can extend through the drainage holes to the outside of the radial direction of the trough bottom of the sink, and the bristles are driven to disturb the drainage holes;

[0016] a converging component connected to the proximal end of the drainage component, the converging component has a converging cavity, the converging cavity is in communication with the drainage cavity, the cerebrospinal fluid entering the drainage cavity through the drainage hole enters the converging cavity under the guidance of the drainage cavity, and is discharged through the drainage tube connected to the converging cavity.

[0017] Preferably, the area corresponding to the trough bottom of the sink is convex radially inward to form a secondary wall, which includes a bottom wall constituting the trough bottom of the sink and side walls on both sides of the bottom wall; wherein:

[0018] The drainage hole is configured as a long slit hole that penetrates the bottom wall in the radial direction and penetrates the side wall in the circumferential direction;

[0019] The movement mode of the disturbing component is configured to drive the disturbing rod to rotate to drive the bristles, so that the bristles pass through the long slit hole in a circumferential movement mode to disturb the long slit hole.

[0020] Preferably, the thickness of the bottom wall and the side wall is smaller than the thickness of the main wall.

[0021] Preferably, the width of both sides in the circumferential direction of the long slit hole is greater than the width of the middle region of the long slit hole.

[0022] Preferably,

[0023] The outer surface of the main wall of the drainage component is provided with drainage grooves arranged in axial direction, extending in circumferential direction and extending to the notch of the sink;

[0024] The outer surface of the drainage component is wrapped with a membrane, which allows the fluid in the cerebrospinal fluid to pass through and intercepts the particulate matter in the cerebrospinal fluid.

[0025] Preferably, both sides of the notch of the sink are configured in an arc structure to increase the non-contact area of the membrane and the drainage component at the notch.

[0026] Preferably, the cerebrospinal fluid drainage device further comprises a drug delivery mechanism;

[0027] The drug delivery mechanism comprises:

[0028] A positioning groove is formed on the outer circumferential surface of the main wall of the drainage component and extends axially, and the positioning groove has a radially outward embedding opening;

[0029] A delivery tube enters and is positioned in the positioning groove through the embedding opening, and the delivery tube is provided with a plurality of drug delivery holes arranged axially and corresponding to the embedding opening;

[0030] A delivery flow channel is formed in the upper part of the drainage component and penetrates to the proximal end of the positioning groove, and the delivery tube is connected to the proximal end port of the delivery flow channel;

[0031] A shunt component is arranged at the proximal end of the drainage component, and the shunt component has a distribution cavity therein, the bottom of the distribution cavity has a distribution opening corresponding to the proximal end port of the delivery flow channel, and a check valve is arranged at the distribution opening to allow the drug to flow from the distribution cavity to the delivery flow channel.

[0032] Preferably, the drainage groove is cut off on both sides of the embedding opening.

[0033] Preferably,

[0034] The drainage component is made of silica gel material, and a skeleton arranged axially and spaced apart is embedded in the drainage component.

[0035] The skeleton has a retracted part matched with the sink, and the skeleton passes through the auxiliary wall of the drainage component.

[0036] The application also discloses a drainage system, comprising:

[0037] The cerebrospinal fluid drainage device according to any one of claims 1 to 6 or the cerebrospinal fluid drainage device according to claim 9;

[0038] A drainage tube, the distal end of which is connected to the cerebrospinal fluid drainage device, and the proximal end of which extends into the cavity of the human body.

[0039] A drainage control module arranged on the drainage tube.

[0040] The application also discloses a drainage system, comprising:

[0041] A drug delivery tube, the distal end of which is connected to the cerebrospinal fluid drainage device.

[0042] A drug delivery module connected to the distal end of the drug delivery tube for providing the drug and controlling the flow and flow rate of the drug.

[0043] Compared with the prior art, the cerebrospinal fluid drainage device and the drainage system provided by the embodiments of the application have the following beneficial effects:

[0044] 1. The drainage device provided by the present invention can significantly reduce the probability of particulate matter in cerebrospinal fluid blocking the drainage hole, making the drainage process smoother.

[0045] 2. Other advantages of the present invention are described in the specific embodiments. Attached Figure Description

[0046] In drawings that are not necessarily drawn to scale, the same reference numerals may describe similar parts in different views. The same reference numerals with or without letter suffixes may indicate different instances of similar parts. The drawings generally illustrate various embodiments by way of example rather than limitation and, together with the description and claims, serve to illustrate embodiments of the invention. Where appropriate, the same reference numerals are used in all drawings to refer to the same or similar parts. Such embodiments are illustrative and not intended to be exhaustive or exclusive embodiments of the apparatus or method.

[0047] Figure 1 This is a schematic diagram of the usage status of a drainage device in the prior art.

[0048] Figure 2 This is a schematic diagram showing the usage state of the drainage system provided by the present invention.

[0049] Figure 3 A three-dimensional structural schematic diagram of a drainage device provided in an embodiment of the present invention (without a membrane).

[0050] Figure 4 This is a three-dimensional schematic diagram of the cross-section of a drainage device provided in an embodiment of the present invention.

[0051] Figure 5 A plan view of the cross-section of a drainage device provided according to an embodiment of the present invention.

[0052] Figure 6 An axial sectional view of a drainage device provided according to an embodiment of the present invention.

[0053] Figure 7 This is a view showing the bottom of a diversion component in a drainage device provided according to an embodiment of the present invention.

[0054] Figure 8 A three-dimensional structural schematic diagram of a drainage device (with a membrane) provided for another embodiment of the present invention.

[0055] Figure 9 A perspective view of the cross-section of a drainage device provided for another embodiment of the present invention.

[0056] Figure 10A plan view of the cross-section of the drainage device provided for another embodiment of the present invention.

[0057] In the picture:

[0058] 100 - Drainage device; 200 - Drainage tube; 300 - Drainage control module; 400 - Drug delivery tube; 500 - Drug delivery module; 1000 - Brain tissue;

[0059] 10-Drainage component; 11-Settling trough; 111-Trough opening; 112-Trough bottom; 113-Arched structure; 12-Long slit hole; 13-Main wall; 131-Drainage groove; 14-Secondary wall; 141-Bottom wall; 142-Side wall; 15-Drainage cavity; 20-Disturbance component; 21-Disturbance rod; 22-Brush bristles; 221-Compliant section; 23-Actuation component; 30-Drug delivery mechanism; 31-Delivery tube; 311-Drug administration port; 312-Positioning groove; 3121-Embedding port; 32-Delivery channel; 33-Diverter component; 331-Distribution cavity; 34-Check valve; 40-Merging component; 41-Merging cavity; 42-Inlet port; 50-Frame; 60-Membrane. Detailed Implementation

[0060] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the described embodiments of the present invention without creative effort are within the scope of protection of the present invention.

[0061] Unless otherwise defined, the technical or scientific terms used in this invention shall have the ordinary meaning understood by one of ordinary skill in the art to which this invention pertains. The terms "first," "second," and similar terms used in this invention do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed following the word and their equivalents, without excluding other elements or objects. Terms such as "connected" or "linked" are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. Terms such as "upper," "lower," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0062] To keep the following description of the embodiments of the present invention clear and concise, detailed descriptions of known functions and known components are omitted.

[0063] like Figure 2 As shown, an embodiment of the present invention discloses a cerebrospinal fluid drainage device 100 and a drainage system including the drainage device 100. In addition to the drainage device 100, the drainage system also includes a guide tube 200 and a drainage control module 300. The drainage device 100 is used to penetrate into the brain tissue 1000 of the human body to drain excess cerebrospinal fluid from the intracranial cavity. The distal end of the guide tube 200 is connected to the drainage device 100, and the proximal end of the guide tube 200 extends into the abdominal cavity of the human body. The cerebrospinal fluid drained from the intracranial cavity flows along the guide tube 200 and is eventually transferred to the abdominal cavity. The drainage control module 300 has a control component, such as a control valve, which is used to control the flow rate, flow velocity, and pressure of the cerebrospinal fluid.

[0064] like Figures 3 to 7 As shown, the drainage device 100 includes: a drainage component 10, a disturbance component 20, and a confluence component 40.

[0065] The drainage component 10 is used to be embedded in the brain tissue 1000 inside the human skull. The drainage component 10 has an axially extending drainage cavity 15. The drainage cavity 15 is closed at the distal end of the drainage component 10 in the axial direction and extends to the proximal end of the drainage component 10 in the axial direction. The confluence component 40 is disposed at the proximal end of the drainage component 10 and communicates with the drainage cavity 15. The confluence component 40 has a confluence cavity 41 inside. The side of the confluence component 40 has an interface communicating with the confluence cavity 41. The distal end of the guide tube 200 is connected to the interface of the confluence component 40, thereby making the drainage cavity 15 communicate with the guide tube 200.

[0066] In this invention: such as Figure 4 As shown, a plurality of circumferentially arranged and axially extended grooves 11 are formed on the outer periphery of the drainage component 10. Each groove 11 is radially constricted inward. The plurality of circumferentially arranged grooves 11 divide the drainage component 10 into a plurality of circumferentially arranged main walls 13. The outer surface of the plurality of main walls 13 includes a cylindrical surface. All grooves 11 are located radially inside the enclosed cylindrical surface. Furthermore, the groove opening 111 of the groove 11 faces the radially outside of the drainage component 10, that is, towards the brain tissue 1000. The circumferential width of the groove opening 111 of the groove 11 is smaller than the circumferential width of the groove bottom 112 of the groove 11. That is, the groove opening 111 of the groove 11 is formed as a constricted opening. Multiple drainage holes are provided in the area where the bottom 112 of each sink 11 is located. The multiple drainage holes are arranged at intervals along the axial direction of the drainage component 10. Each drainage hole extends to the drainage cavity 15, so that the drainage cavity 15 is connected to the sink 11 through the drainage hole. The sink 11 is connected to the space on the radial outer side of the drainage component 10 (i.e., the space where the brain tissue 1000 is located) through the slot 111.

[0067] The disturbance component 20 includes an actuating component 23, a disturbance rod 21, and bristles 22 arranged on the disturbance rod 21. The disturbance rod 21 extends from the proximal end of the drainage component 10 into the drainage cavity 15. The bristles 22 correspond to each drainage hole, and the bristles 22 are always located in the drainage hole or pass through the drainage hole by movement. In this invention, the length of the bristles 22 is configured such that the radially outer ends of the bristles 22 extend beyond the outer port of the drainage hole. That is, compared to the bristles 22 in the prior art, the bristles 22 in this invention completely pass through the drainage hole. Thus, when the bristles 22 are disturbed in the drainage hole, the bristles 22 can disturb any area of ​​the drainage hole. That is, the bristles 22 can disturb the inner port, middle region, and outer port of the drainage hole, thereby effectively preventing particulate matter (e.g., protein particles) in the cerebrospinal fluid from accumulating in the inner port (and its surrounding area), middle region, and outer port (and its surrounding area) of the drainage hole, thereby effectively preventing particulate matter from blocking the drainage hole in any area.

[0068] The drainage process of the drainage device 100 is described below.

[0069] After the drainage component 10 invades the intracranial brain tissue 1000, the intracranial cerebrospinal fluid first enters the sink 11 through the slot 111 of the sink 11. Then, the cerebrospinal fluid enters the drainage cavity 15 through the drainage hole. Then, the cerebrospinal fluid flows upward along the drainage cavity 15 and enters the confluence cavity 41 of the confluence component 40. The cerebrospinal fluid that enters the confluence cavity 41 then enters the drainage tube 200 and finally enters the abdominal cavity of the human body along the drainage tube 200.

[0070] Periodically or consistently, the actuating component 23 applies energy (e.g., ultrasonic or electromagnetic energy) directly to the bristles 22 or applies energy (e.g., mechanical energy) to the bristles 22 via the agitator 21, causing the bristles 22 to agitate the drainage hole. This is to prevent particulate matter in the cerebrospinal fluid from accumulating in any area of ​​the drainage hole or to break up any particulate matter that has accumulated in any area of ​​the drainage hole, thereby avoiding blockage of the drainage hole.

[0071] As can be seen from the above, the key to the drainage device 100 of the present invention being able to prevent particulate matter from blocking the drainage hole at any position is that the radial distal end of the bristles 22 extends out of the radial outer end of the drainage hole, that is, the bristles 22 completely pass through the drainage hole.

[0072] Importantly, in this invention, compared to existing technologies, allowing the bristles 22 to completely pass through the drainage hole does not result in the radially outer ends of the bristles 22 damaging the brain tissue 1000 (or, the probability of damaging the brain tissue 1000 is significantly reduced). This is because, in this invention, as... Figure 5As shown, the drainage component 10 is provided with a radially constricted groove 11, and the drainage hole is arranged in the area where the bottom 112 of the groove 11 is located. The bottom 112 of the groove 11 is a certain distance away from the cylindrical surface included by the main wall 13, so that the drainage hole is a certain distance from the brain tissue 1000. Therefore, although the radially outer end of the bristles 22 extends into the groove 11, the probability of the bristles 22 contacting the brain tissue 1000 is also low. Furthermore, by configuring the groove 11 such that the width of the groove opening 111 is smaller than the width of the groove bottom 112, that is, configuring the groove opening 111 of the groove 11 as a constricted opening, the radial inward intrusion of the brain tissue 1000 into the groove 11 can be effectively inhibited, thereby further reducing the probability of the bristles 22 contacting the brain tissue 1000.

[0073] In some preferred structures, such as Figure 4 and Figure 5 As shown, the area corresponding to the bottom 112 of the settling tank 11 protrudes radially inward to form a secondary wall 14. This secondary wall 14 includes a bottom wall 141 constituting the bottom 112 of the settling tank 11 and side walls 142 located on both sides of the bottom wall 141. The drainage hole is configured as follows: the drainage hole is a long slit hole 12 that radially penetrates the bottom wall 141 and circumferentially penetrates the side wall 142. The bristles 22 are arranged such that multiple layers of bristles 22 are spaced apart along the axial direction, each layer of bristles 22 including multiple sets of bristle units arranged circumferentially, each set of bristle units corresponding to one long slit hole 12. The movement of the disturbance component 20 is configured such that a micro motor is used as the actuating component 23. This micro motor is located near the end of the drainage component 10, and the end of the disturbance rod 21 is connected to the micro motor. The micro motor drives the disturbance rod 21 to rotate, thereby driving the bristles 22 so that the bristles 22 move circumferentially through the elongated slit hole 12 and disturb the elongated slit hole 12. The advantages of this configuration are: firstly, when it is not necessary to disturb the drainage hole, the micro motor drives the disturbance rod 21 to keep the bristle unit outside the drainage hole, thereby avoiding the bristle unit from obstructing the drainage process. When it is necessary to disturb the drainage hole, the micro motor drives the disturbance rod 21 to drive the bristle unit from one side of the outlet hole into the drainage hole and disturb the drainage hole; secondly, it simplifies the disturbance of the drainage hole by the bristles 22, that is, it is only necessary to use mechanical force to drive the disturbance rod 21 to drive the bristle unit through the drainage hole, and it can be driven only by the micro motor.

[0074] In some more preferred structures, the thickness of the bottom wall 141 and the side wall 142 is much smaller than the thickness of the main wall 13, that is, the thickness of the bottom wall 141 and the side wall 142 is minimized as much as possible to significantly reduce the radial size of the elongated slit 12, which can significantly suppress the accumulation of particulate matter in the elongated slit 12 and facilitate the cleaning of the accumulated particulate matter.

[0075] In some more preferred configurations, the drainage component 10 is integrally injection molded from a flexible material such as silicone, and the thickness of the main wall 13 is increased as much as possible to increase the rigidity of the drainage component 10 on the one hand, and to enable the main wall 13 to be configured with other structures (e.g., positioning groove 312, which will be described below).

[0076] In some preferred configurations, an axially spaced skeleton 50 is embedded inside the drainage component 10. This skeleton 50 has an inwardly recessed portion adapted to the settling tank 11, and passes through the secondary wall 14 of the drainage component 10. The skeleton 50 and the drainage component 10 are integrally injection molded. The purpose of embedding the skeleton 50 is to provide radial support to the drainage component 10 without affecting its compliant bending, thus preventing radial contraction of the drainage component 10 due to the weakness of the secondary wall 14, and consequently preventing deformation of the settling tank 11.

[0077] In some preferred configurations, the width of the two sides of the circumferentially oriented slit 12 is greater than the width of the central region of the slit 12. This guides the bristle units, making it easier for them to enter the slit 12 from one side of the circumferentially oriented slit 12.

[0078] In some more preferred configurations, the bristles 22 are configured as follows: the bristles 22 are formed by a composite of metal wire (or other rigid filaments) and silicone. Specifically, the metal wire serves as the core wire, and the silicone covers the metal wire. Furthermore, the metal wire does not extend to the radially outer side of the bristles 22, and the radially outer side of the bristles 22 is entirely made of silicone material. Thus, the radially outer side of the bristles 22 is formed as a compliant segment 221. This compliant segment 221 is relatively soft, so that even if the radially outer side of the bristles 22 comes into contact with the brain tissue 1000 during the circumferential movement of the bristles 22 through the drainage hole, the contact area is the compliant segment 221, and therefore, it will hardly cause any damage to the brain tissue 1000.

[0079] In a preferred embodiment provided by the present invention, such as Figures 8 to 10As shown, a membrane 60 is wrapped around the drainage component 10. Specifically, the membrane 60 is configured to allow the liquid portion of cerebrospinal fluid to pass through while intercepting particulate matter. The membrane 60 can be obtained by using a biocompatible filter membrane or by laser perforation (micropores) on a thin film. Numerous drainage grooves 131 are machined on the outer surface of all the main walls 13 of the drainage component 10. These drainage grooves 131 are axially spaced and extend circumferentially to the opening 111 of the settling tank 11. In this way, cerebrospinal fluid in the area outside the circumferential direction of the opening 111 of the settling tank 11 (i.e., the area corresponding to the main wall 13) can pass through the membrane 60 into the drainage grooves 131, and flow laterally under the guidance of the drainage grooves 131 into the opening 111, and then into the settling tank 11. Therefore, the advantages of wrapping the membrane 60 on the drainage component 10 and arranging the drainage groove 131 on the main wall 13 of the drainage component 10 are: on the one hand, it can increase the contact area for drainage, thereby increasing the drainage volume, which is especially beneficial for drainage when the brain tissue 1000 is in contact with the main wall 13; on the other hand, it prevents the brain tissue 1000 from invading into the sink 11 at the groove opening 111, thereby facilitating the extraction of the drainage component 10 from the brain tissue 1000 and avoiding a reduction in the opening of the groove opening 111.

[0080] In some preferred configurations, the two sides of the opening 111 of the settling tank 11 are configured as arc-shaped structures 113. This makes the non-contact area between the diaphragm 60 and the drainage component 10 at the opening 111 much larger than the width of the opening 111. This allows more cerebrospinal fluid to enter the settling tank 11 directly through the opening 111, reducing the obstruction of the brain tissue 1000 to the cerebrospinal fluid.

[0081] In a preferred embodiment provided by the present invention, such as Figures 2 to 7 As shown, the drainage device 100 is further provided with a drug delivery mechanism 30, and correspondingly, the drainage system is further provided with a drug delivery tube 400 and a drug delivery module 500. The drug delivery mechanism 30 includes: a positioning groove 312, a delivery tube 31, a delivery channel 32, and a diversion component 33.

[0082] Each drainage component 10 has an axially extending positioning groove 312 on the outer surface of its main wall 13. The positioning groove 312 has a radially outwardly facing insertion port 3121. The positioning groove 312 is configured with a cross-section of an arc. The delivery tube 31 enters the positioning groove 312 through the insertion port 3121 and is held in the positioning groove 312. The distal end of the delivery tube 31 is closed. The delivery tube 31 has axially spaced drug administration holes 311 on its radially outwardly facing tube wall. The upper part of the drainage component 10 is provided with a delivery channel 32 corresponding to the delivery tube 31. The two ends of the delivery channel 32 are respectively connected to the proximal end of the drainage component 10 and the proximal end of the delivery tube 31. The proximal end of the delivery tube 31 is connected to the distal end of the delivery channel 32, thereby communicating with the delivery channel 32. The diversion component 33 is located at the proximal end of the drainage component 10. The diversion component 33 has a dispensing chamber 331. The bottom of the dispensing chamber 331 has dispensing ports that respectively mate with the proximal ports of the delivery channel 32. The proximal end of the delivery channel 32 corresponds to the dispensing ports, thereby enabling communication between the dispensing chamber 331 and the delivery channel 32. Each dispensing port is equipped with a check valve 34, which allows fluid medication in the dispensing chamber 331 to enter the delivery channel 32 while restricting fluid from flowing back from the delivery channel 32 into the dispensing chamber 331. The diversion component 33 has an interface communicating with the dispensing chamber 331. The distal end of the administration tube 400 is connected to the interface of the diversion component 33. The administration module 500 is connected to the proximal end of the administration tube 400. The administration module 500 can be attached to a flat area of ​​the human body, such as the back or abdomen. The administration module 500 is used to supply medication to the administration tube 400 and to control the flow rate and velocity of the medication.

[0083] The following describes the process by which the drainage system delivers drugs to brain tissue 1000.

[0084] The drainage process and the drug delivery process are alternated. When the cerebrospinal fluid is drained using the drainage component 10, the drug delivery module 500 is closed. At this time, the cerebrospinal fluid is transferred to the abdominal cavity through the drainage hole, the drainage cavity 15 and the guide tube 200. During drainage, a check valve 34 is provided at the distribution port of the diversion component 33 to restrict the flow of cerebrospinal fluid into the distribution cavity 331 of the diversion component 33, so as to avoid contamination of the drug.

[0085] When drug delivery is required, the drainage control module 300 closes the drainage tube 200 in advance, and the drug delivery module 500 provides power so that the drug enters the distribution chamber 331 of the diversion component 33 through the drug delivery tube 400. Then, it enters each delivery tube 31 through the check valve 34 and the delivery channel 32, and then delivers the drug to the brain tissue 1000 through the drug delivery port 311 of the delivery tube 31.

[0086] In some preferred structures, such as Figure 9As shown, the drainage groove 131 ends at both sides of the insertion port 3121, thereby preventing the drug from flowing along the drainage groove 131 to the settling tank 11 to a certain extent when delivering the drug.

[0087] In some preferred structures, such as Figure 6 As shown, the diversion component 33 and the confluence component 40 are stacked axially, and the diversion component 33 is directly connected to the drainage component 10. A reserved cavity is provided between the diversion component 33 and the confluence component 40. An inlet hole 42 is provided at the bottom of the confluence component 40. During drainage, the cerebrospinal fluid passes through the reserved cavity and enters the confluence cavity 41 through the inlet hole 42.

[0088] Furthermore, although exemplary embodiments have been described in this invention, their scope includes any and all embodiments based on the invention that have equivalent elements, modifications, omissions, combinations (e.g., schemes involving intersections of various embodiments), adaptations, or alterations. Elements in the claims will be interpreted broadly based on the language used in the claims and are not limited to the examples described in this specification or during the implementation of this application, and such examples will be interpreted as non-exclusive. Therefore, this specification and examples are intended to be considered illustrative only, and the true scope and spirit are indicated by the full scope of the following claims and their equivalents.

[0089] The above description is intended to be illustrative and not restrictive. For example, the above examples (or one or more of them) can be used in combination with each other. Other embodiments can be used by those skilled in the art when reading the above description. Furthermore, in the above detailed description, various features may be grouped together to simplify the invention. This should not be construed as an intention that a disclosed feature, which is not claimed, is necessary for any claim. Rather, the subject matter of the invention may be less than all the features of the particular disclosed embodiments. Thus, the following claims are incorporated herein by reference as examples or embodiments, wherein each claim is independently considered as a separate embodiment, and these embodiments are contemplated as being able to be combined with each other in various combinations or arrangements. The scope of the invention should be determined by reference to the appended claims and the full scope of their equivalents.

[0090] The above embodiments are merely exemplary embodiments of the present invention and are not intended to limit the present invention. The scope of protection of the present invention is defined by the claims. Those skilled in the art can make various modifications or equivalent substitutions to the present invention within its spirit and scope of protection, and such modifications or equivalent substitutions should also be considered to fall within the scope of protection of the present invention.

Claims

1. A cerebrospinal fluid drainage device, characterized in that, include: A rod-shaped drainage component has an axially extending drainage cavity inside. Multiple radially inwardly tapering grooves are formed on the outer periphery of the drainage component, arranged circumferentially and extending axially. The width of the groove opening in the circumferential direction of each groove is smaller than the width of the groove bottom in the circumferential direction. The multiple grooves divide the drainage component into multiple circumferentially arranged main walls. The outer surfaces of the multiple main walls are enveloped into cylindrical surfaces; A drainage hole is formed at the bottom of the settling tank so that the drainage cavity communicates with the settling tank; A disturbance component includes a disturbance rod and radially extending bristles arranged on the disturbance rod. The disturbance rod extends from the proximal end of the drainage component into the drainage cavity, and the bristles correspond to the drainage hole. The distal ends of the bristles can pass through the drainage hole and extend radially outward from the bottom of the settling tank. The bristles are driven to disturb the drainage hole. A manifold is connected to the proximal end of the drainage component. The manifold has a manifold cavity that communicates with the drainage cavity. Cerebrospinal fluid that enters the drainage cavity through the drainage hole is guided into the manifold cavity by the drainage cavity and is discharged through a guide tube connected to the manifold cavity.

2. The cerebrospinal fluid drainage device according to claim 1, characterized in that, This causes the area corresponding to the bottom of the settling tank to bulge radially inward to form a secondary wall, the secondary wall including a bottom wall constituting the bottom of the settling tank and side walls located on both sides of the bottom wall; wherein: The drainage hole is configured as a long slit hole that penetrates the bottom wall radially and the side wall circumferentially. The movement of the disturbance component is configured such that the disturbance rod is driven to rotate to move the bristles, so that the bristles move circumferentially through the elongated slit and disturb the elongated slit.

3. The cerebrospinal fluid drainage device according to claim 2, characterized in that, The thickness of the bottom wall and the side wall is less than the thickness of the main wall.

4. The cerebrospinal fluid drainage device according to claim 2, characterized in that, The width of the two sides of the elongated slit in the circumferential direction is greater than the width of the central region of the elongated slit.

5. The cerebrospinal fluid drainage device according to claim 1, characterized in that, The outer surface of the main wall of the drainage component is provided with drainage grooves that are spaced apart along the axial direction, extend circumferentially, and extend to the opening of the settling tank. The outer surface of the drainage component is covered with a membrane that allows fluid in the cerebrospinal fluid to pass through while intercepting particulate matter in the cerebrospinal fluid.

6. The cerebrospinal fluid drainage device according to claim 5, characterized in that, The two sides of the groove opening of the settling tank are configured with an arc-shaped structure to increase the non-contact area between the diaphragm and the drainage component at the groove opening.

7. The cerebrospinal fluid drainage device according to claim 5, characterized in that, The cerebrospinal fluid drainage device also includes a drug delivery mechanism; The drug delivery facility includes: A positioning groove is formed on the outer peripheral surface of the main wall of the drainage component and extends axially, the positioning groove having a radially outward insert opening; The delivery tube enters the positioning groove through the insertion port and is positioned in the positioning groove. The delivery tube has drug delivery holes arranged at intervals along the axial direction in the area corresponding to the insertion port. A delivery channel is formed in the upper part of the drainage component and extends to the proximal end of the positioning groove, and the delivery tube is connected to the proximal port of the delivery channel; A diversion component is disposed at the proximal end of the drainage component. The diversion component has a dispensing chamber. The bottom of the dispensing chamber has dispensing ports that respectively connect to the proximal ports of the delivery channel. A check valve is provided at the dispensing ports to allow the drug to flow from the dispensing chamber to the delivery channel while preventing backflow.

8. The cerebrospinal fluid drainage device according to claim 7, characterized in that, The drainage groove ends at both sides of the embedding port.

9. The cerebrospinal fluid drainage device according to claim 2, characterized in that, The drainage component is made of silicone material, and a skeleton arranged at intervals along the axial direction is embedded in the drainage component; The skeleton has an inwardly recessed portion adapted to the settling tank, and the skeleton passes through the secondary wall of the drainage component.

10. A drainage system, characterized in that, include: The cerebrospinal fluid drainage device as described in any one of claims 1 to 6 or the cerebrospinal fluid drainage device as described in claim 9; A drainage tube, the distal end of which is connected to the cerebrospinal fluid drainage device, and the proximal end of which extends into a cavity of the human body; A drainage control module is installed on the drainage tube.

11. A drainage system, characterized in that, include: The cerebrospinal fluid drainage device as described in claim 7 or 8; A drainage tube, the distal end of which is connected to the cerebrospinal fluid drainage device, and the proximal end of which extends into a cavity of the human body; A drainage control module is disposed on the drainage tube; A drug delivery tube, the distal end of which is connected to the cerebrospinal fluid drainage device; A drug delivery module, which is connected to the distal end of the drug delivery tube, is used to deliver the drug and control the flow and rate of the drug.

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