A method and system for controlling infusion based on loss of fluid balance

Abstract

The present invention relates to an infusion control method and system based on loss of fluid replacement balance, belonging to the field of medical monitoring. The method includes obtaining an infusion evaluation index, wherein the infusion evaluation index includes an environmental evaluation index and a human evaluation index; calculating an initial infusion index according to the infusion evaluation index, establishing an initial infusion index model according to the initial infusion index, and outputting initial infusion information corresponding to the initial infusion index through the initial infusion index model; obtaining an appropriate infusion temperature, a real-time fluid loss of a human body, and a real-time fluid replacement amount of a human body according to the initial infusion information, and performing intelligent infusion control, wherein the intelligent infusion control includes an infusion heating operation and a loss of fluid replacement balance operation; when the real-time fluid replacement amount of a human body is twice the real-time fluid loss amount of a human body, a termination infusion instruction is generated, the intelligent infusion control is terminated by the termination infusion instruction, and a buzzer is triggered to sound an alarm. The present invention solves the problem that infusion liquids are easily solidified and frozen in plateau areas, and at the same time achieves the purpose of intelligently controlling the infusion amount according to the balance of human body fluids.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical monitoring, and in particular relates to an infusion control method and system based on loss of fluid replacement balance. Background Art

[0002] Entering a plateau from a plain or from a plateau to a higher altitude area will cause the human body to undergo a series of plateau hypoxia stress reactions. People with altitude sickness need to be transferred to a warm place indoors for infusion treatment. However, it is difficult to transfer people in plateau areas, which can easily cause secondary injuries or delay the best treatment time during the transfer process. If one intends to implement plateau infusion treatment, one needs to solve problems such as the infusion fluid easily solidifies and freezes, the infusion volume is difficult to control, and the body's fluid balance affects the effect of infusion treatment. Summary of the invention

[0003] In order to solve the above problems existing in the prior art, the present invention provides an infusion control method and system based on loss of fluid replacement balance;

[0004] The purpose of the present invention can be achieved through the following technical solutions:

[0005] A method for controlling an infusion based on a loss of fluid replacement balance, the implementation of the infusion control method comprising the following steps:

[0006] S1: Obtaining an infusion evaluation index, wherein the infusion evaluation index includes an environment evaluation index and a human evaluation index, wherein the human evaluation index includes a human health index and a human oxygen content index;

[0007] S2: calculating an initial infusion index according to the infusion evaluation index, establishing an initial infusion index model according to the initial infusion index, and outputting initial infusion information corresponding to the initial infusion index through the initial infusion index model, wherein the initial infusion index includes an initial infusion volume index and an initial infusion flow rate index, the initial infusion index model includes an initial infusion volume index model and an initial infusion flow rate index model, and the initial infusion information includes initial infusion volume information and initial infusion flow rate information;

[0008] S3: according to the initial infusion information, the appropriate infusion temperature, the real-time fluid loss of the human body, and the real-time fluid replacement volume of the human body are obtained, and intelligent infusion control is performed, wherein the intelligent infusion control includes an infusion heating operation and a loss-replenishment balance operation;

[0009] S4: When the real-time fluid replenishment volume of the human body is twice the real-time fluid loss volume of the human body, an infusion termination instruction is generated, the intelligent infusion control is terminated by the infusion termination instruction, and the buzzer is triggered to sound an alarm.

[0010] Preferably, the environmental evaluation indicators include atmospheric pressure, altitude, ambient temperature, atmospheric oxygen concentration, water vapor partial pressure, and oxygen flow; the human health indicators include systolic blood pressure, diastolic blood pressure, pulse, respiratory rate, gender index, gender coefficient, mean pulmonary artery pressure, age index, respiratory quotient, arterial carbon dioxide partial pressure, plateau exposure time, and body weight; the human oxygen content indicators include inspired oxygen concentration, inspired oxygen partial pressure, and arterial oxygen partial pressure.

[0011] Preferably, the step S2 specifically includes:

[0012] S201: Establishing the initial infusion volume index model by calculating the initial infusion volume index based on the infusion evaluation index. The calculation formula of the initial infusion volume index is:

[0013]

[0014] Among them, f L is the initial infusion volume index, To round down, E is the altitude, is the gender index, with a value of 1 for females and 0.5 for males, FIO2 is the fraction of inspired oxygen, PIO2 is the partial pressure of inspired oxygen, β is the age index, with a value of 0.1 for those under 14 years old, 0.8 for those between 14 and 60 years old, and 0.5 for those over 60 years old, PaO2 is the partial pressure of oxygen in arterial blood, SBP is the systolic blood pressure, DBP is the diastolic blood pressure, P is the pulse, is the water vapor partial pressure;

[0015] S202: Outputting the initial infusion volume information through the initial infusion volume index model, wherein the initial infusion volume information includes low initial infusion volume information and high initial infusion volume information;

[0016] Acquire an initial infusion volume threshold, and obtain the initial infusion volume information by comparing the initial infusion volume index with the initial infusion volume threshold;

[0017] Determine the initial infusion volume index, and when the initial infusion volume index is less than or equal to the initial infusion volume threshold, feedback the low initial infusion volume information, wherein the low initial infusion volume information is 65% of the maximum limit infusion volume of the therapeutic drug, in milliliters per day;

[0018] When the initial infusion volume index is greater than the initial infusion volume threshold, the high initial infusion volume information is fed back, and the high initial infusion volume information is 80% of the maximum limit infusion volume of the therapeutic drug, in milliliters per day;

[0019] S203: Establishing the initial infusion flow rate index model by calculating the initial infusion flow rate index based on the infusion evaluation index. The calculation formula of the initial infusion flow rate index is:

[0020]

[0021] Where fv is the initial infusion flow rate index, To round down, is the gender index, with females taking the value of 0.5 and males taking the value of 1, β is the age index, with those under 14 years old taking the value of 0.1, those aged 14 to 60 years old taking the value of 0.5, and those aged 60 years and above taking the value of 0.8, t is the plateau exposure time, O is the respiratory rate, PAPm is the mean pulmonary artery pressure, T is the ambient temperature, and PaO2 is the partial pressure of oxygen in arterial blood;

[0022] S204: Outputting the initial infusion flow rate information according to the initial infusion flow rate index model, wherein the initial infusion flow rate information includes low initial infusion flow rate information and high initial infusion flow rate information;

[0023] Acquire an initial infusion flow rate threshold, and obtain the initial infusion flow rate information by comparing the initial infusion flow rate index with the initial infusion flow rate threshold;

[0024] Determine the initial infusion flow rate index, and when the initial infusion flow rate index is less than or equal to the initial infusion flow rate threshold, feedback the low initial infusion flow rate information, wherein the low initial infusion flow rate information is 65% of the maximum limit infusion flow rate of the therapeutic drug, in drops per minute;

[0025] When the initial infusion flow rate index is greater than the initial infusion flow rate threshold, the high initial infusion flow rate information is fed back, and the high initial infusion flow rate information is 80% of the maximum limit infusion flow rate of the therapeutic drug, in drops per minute.

[0026] Preferably, the step S3 specifically includes:

[0027] S301: performing the infusion heating operation by an infusion heating device according to the initial infusion flow rate information;

[0028] S302: performing the loss-replenishment balance operation through an infusion clamp based on the real-time fluid loss and the real-time fluid replacement of the human body, wherein the real-time fluid replacement of the human body is the infusion volume that has been injected into the patient's body.

[0029] Preferably, the step S301 specifically includes:

[0030] S301-1: Obtain the infusion liquid temperature through a temperature sensor, and calculate the appropriate infusion temperature according to the ambient temperature. The calculation formula is:

[0031] T max =6.1163×T-0.0187×V d-0.3125×T 2 +0.0051×T 3 -0.0001×V d 2

[0032] Among them, T max is the suitable temperature for infusion, T is the ambient temperature, V d is the initial infusion flow rate information;

[0033] S301-2: Perform the infusion heating operation according to the suitable infusion temperature through the infusion heating device until the infusion liquid temperature reaches the suitable infusion temperature.

[0034] Preferably, the step S302 specifically includes:

[0035] S302-1: Detect the patient's actual blood sodium concentration using a blood sodium concentration detection kit, and calculate the real-time fluid loss of the human body according to the patient's actual blood sodium concentration. The calculation formula is:

[0036] H=G×ξ(C' Na -C Na )

[0037] Among them, H is the real-time fluid loss of the human body, G is the body weight, ξ is the gender coefficient, which is 3 for females and 4 for males, and C' Na The actual blood sodium concentration of the patient, C Na Normal blood sodium concentration is 140 mmol per liter;

[0038] S302-2: obtaining fluid loss and replacement balance information based on the real-time fluid loss of the human body, wherein the fluid loss and replacement balance information includes fluid flow rate acceleration information and fluid flow rate reduction information;

[0039] Acquire the real-time fluid replenishment volume of the human body, and obtain the fluid loss-replenishment balance information by comparing the real-time fluid replenishment volume of the human body with the real-time fluid loss volume of the human body;

[0040] Determine the real-time fluid replenishment volume of the human body, and when the real-time fluid replenishment volume of the human body is less than the real-time fluid loss volume of the human body, feedback the information of accelerating the infusion flow rate;

[0041] When the real-time fluid replenishment volume of the human body is greater than or equal to the real-time fluid loss volume of the human body, the infusion flow rate slowing down information is fed back;

[0042] S302-3: Transmitting the fluid replacement balance information to the stepper motor, and the stepper motor performs the fluid replacement balance operation by controlling the infusion clamp.

[0043] Preferably, the step S302-3 specifically includes:

[0044] The fluid balance loss information is processed by an intermediate frequency filter to obtain an intermediate frequency fluid balance loss signal, and the intermediate frequency fluid balance loss signal is expressed as:

[0045]

[0046] Among them, S IF (t X ) is the intermediate frequency fluid balance signal, r is the fluid balance information, A IF is the amplitude of the intermediate frequency fluid imbalance signal, f IF is the center frequency of the intermediate frequency loss of fluid balance signal, t X The duration of the fluid balance loss information, is the initial phase of the intermediate frequency fluid balance signal, h IF (t X ) is an intermediate frequency filter;

[0047] The intermediate frequency loss-of-replenishment balance signal is mixed by a local oscillator and a mixer to obtain a transmission loss-of-replenishment balance signal, and the transmission loss-of-replenishment balance signal is expressed as:

[0048]

[0049] Among them, S RF (t X ) is used to send a signal of loss of fluid balance, S IF (t X ) is the intermediate frequency loss of fluid balance signal, A RF is the amplitude of the transmitted signal of loss of replenishment balance, f0 is the center frequency of the transmitted signal of loss of replenishment balance, and f IF is the center frequency of the intermediate frequency loss of fluid balance signal, t X The duration of the fluid balance loss information, To send the initial phase of the signal of loss of fluid balance, h IF (t X ) is an intermediate frequency filter;

[0050] The stepper motor receives the transmitted fluid replacement balance signal to obtain a received fluid replacement balance signal, wherein the received fluid replacement balance signal includes the transmitted fluid replacement balance signal, noise, and interference signal. The received fluid replacement balance signal is expressed as:

[0051]

[0052] Among them, r(t X ) is the signal of receiving fluid balance loss, t X is the duration of fluid balance loss information, S RF (t X ) is to send the signal of loss of fluid balance, n(t X) is noise, i(t X ) is the interference signal, f IF is the center frequency of the intermediate frequency loss of liquid replenishment balance signal, It is the initial phase of the intermediate frequency loss of fluid balance signal;

[0053] The interference loss of fluid replenishment balance signal is obtained through the signal anti-interference network to obtain the loss of fluid replenishment balance signal after interference suppression. The expression of the loss of fluid replenishment balance signal after interference suppression is:

[0054] λ(t X )=r(t X )-r'(t X )

[0055] Among them, λ(t X ) is the signal of loss of fluid balance after interference suppression, r(t X ) receives the signal of loss of fluid balance, r'(t X ) is the interference signal of loss of fluid balance;

[0056] The stepper motor performs the fluid replacement balance operation by controlling the infusion clamp according to the interference suppressed fluid replacement balance signal.

[0057] An infusion control system based on loss of fluid replacement balance, used to execute the above-mentioned infusion control method, characterized by comprising a data acquisition module, an initial infusion information output module, an intelligent infusion control module, and an intelligent infusion termination module;

[0058] The data acquisition module is used to obtain infusion evaluation indicators, which include environmental evaluation indicators and human evaluation indicators. The environmental evaluation indicators include atmospheric pressure, altitude, ambient temperature, atmospheric oxygen concentration, water vapor partial pressure, and oxygen flow. The human evaluation indicators include human health indicators and human oxygen content indicators. The human health indicators include systolic pressure, diastolic pressure, pulse, respiratory rate, gender index, gender coefficient, mean pulmonary artery pressure, age index, respiratory quotient, arterial carbon dioxide partial pressure, plateau exposure time, and body weight. The human oxygen content indicators include inspired oxygen concentration, inspired oxygen partial pressure, and arterial oxygen partial pressure.

[0059] The initial infusion information output module is used to calculate the initial infusion index according to the infusion evaluation index, establish an initial infusion index model according to the initial infusion index, and output the initial infusion information corresponding to the initial infusion index through the initial infusion index model, wherein the initial infusion index includes an initial infusion volume index and an initial infusion flow rate index, the initial infusion index model includes an initial infusion volume index model and an initial infusion flow rate index model, and the initial infusion information includes initial infusion volume information and initial infusion flow rate information;

[0060] The intelligent infusion control module is used to obtain the appropriate infusion temperature, the real-time human body fluid loss, and the real-time human body fluid replacement according to the initial infusion information and perform intelligent infusion control, wherein the intelligent infusion control includes an infusion heating operation and a loss-replenishment balance operation;

[0061] The intelligent infusion termination module is used to generate an infusion termination instruction when the real-time fluid replenishment volume of the human body is twice the real-time fluid loss volume of the human body, terminate the intelligent infusion control through the infusion termination instruction, and trigger the buzzer to sound an alarm.

[0062] The beneficial effects of the present invention are:

[0063] (1) The problem of easy freezing of infusion fluids in plateaus can be solved by heating the infusion fluid, and the infusion volume can be intelligently controlled according to the body fluid balance of the human body through the loss of fluid balance operation, so as to achieve on-site rescue of patients and reduce the harm that may be caused by secondary transportation of patients;

[0064] (2) By calculating the initial infusion index based on the infusion evaluation index, an initial infusion index model is established to output the initial infusion information, so as to timely judge the patient's condition, use medication as needed, and achieve rapid and reasonable rescue of patients;

[0065] (3) By using an infusion heating device to warm the infusion according to the appropriate infusion temperature, until the infusion liquid temperature reaches the appropriate infusion temperature, the drug coagulation caused by too low a temperature or the drug ineffectiveness caused by too high a temperature can be minimized;

[0066] (4) Obtaining the interference loss of fluid balance signal through the signal anti-interference network to obtain the loss of fluid balance signal after interference suppression, eliminating the interference signal during the infusion process, and preventing the infusion device from triggering the termination of infusion information after receiving the interference signal. BRIEF DESCRIPTION OF THE DRAWINGS

[0067] In order to facilitate understanding by those skilled in the art, the present invention is further described below with reference to the accompanying drawings.

[0068] Figure 1 The present invention is a flow chart of the steps of an infusion control method based on loss of fluid replacement balance. DETAILED DESCRIPTION

[0069] In order to further explain the technical means and effects adopted by the present invention to achieve the predetermined invention purpose, the specific implementation methods, structures, features and effects of the present invention are described in detail below in conjunction with the accompanying drawings and preferred embodiments.

[0070] The working principle and use process of the present invention:

[0071] See also Figure 1 , a method for controlling infusion based on loss of fluid balance, comprising:

[0072] S1: Obtain infusion evaluation indicators, the infusion evaluation indicators include environmental evaluation indicators and human evaluation indicators, the environmental evaluation indicators include atmospheric pressure, altitude, ambient temperature, atmospheric oxygen concentration, water vapor partial pressure, oxygen flow, the human evaluation indicators include human health indicators and human oxygen content indicators, the human health indicators include systolic blood pressure, diastolic blood pressure, pulse, respiratory rate, gender index, gender coefficient, pulmonary artery mean pressure, age index, respiratory quotient, arterial carbon dioxide partial pressure, plateau exposure time, body weight, the human oxygen content indicators include inspired oxygen concentration, inspired oxygen partial pressure, arterial oxygen partial pressure;

[0073] S2: calculating an initial infusion index according to the infusion evaluation index, establishing an initial infusion index model according to the initial infusion index, and outputting initial infusion information corresponding to the initial infusion index through the initial infusion index model, wherein the initial infusion index includes an initial infusion volume index and an initial infusion flow rate index, the initial infusion index model includes an initial infusion volume index model and an initial infusion flow rate index model, and the initial infusion information includes initial infusion volume information and initial infusion flow rate information;

[0074] S3: according to the initial infusion information, the appropriate infusion temperature, the real-time fluid loss of the human body, and the real-time fluid replacement volume of the human body are obtained, and intelligent infusion control is performed, wherein the intelligent infusion control includes an infusion heating operation and a loss-replenishment balance operation;

[0075] S4: When the real-time fluid replenishment volume of the human body is twice the real-time fluid loss volume of the human body, an infusion termination instruction is generated, the intelligent infusion control is terminated by the infusion termination instruction, and the buzzer is triggered to sound an alarm.

[0076] In this embodiment, an infusion evaluation index is obtained, and the infusion evaluation index includes an environmental evaluation index and a human evaluation index. The environmental evaluation index includes atmospheric pressure, altitude, ambient temperature, atmospheric oxygen concentration, water vapor partial pressure, and oxygen flow. The human evaluation index includes a human health index and a human oxygen content index. The human health index includes systolic pressure, diastolic pressure, pulse, respiratory rate, gender index, gender coefficient, mean pulmonary artery pressure, age index, respiratory quotient, arterial carbon dioxide partial pressure, plateau exposure time, and body weight. The human oxygen content index includes inspired oxygen concentration, inspired oxygen partial pressure, and arterial oxygen partial pressure. The specific implementation can be performed by the following steps:

[0077] The calculation formula for the inspired oxygen concentration is:

[0078]

[0079] Wherein, FIO2 is the inspired oxygen concentration, in %; is the atmospheric oxygen concentration, in %; is the oxygen flow rate in liters per minute;

[0080] The calculation formula for the inspired oxygen partial pressure is:

[0081]

[0082] Where PIO2 is the partial pressure of inspired oxygen, expressed in millimeters of mercury; P B is the atmospheric pressure in millimeters of mercury; is the water vapor partial pressure in millimeters of mercury;

[0083] The arterial oxygen partial pressure calculation formula is:

[0084]

[0085] Among them, PaO2 is the partial pressure of oxygen in arterial blood, in millimeters of mercury; PIO2 is the partial pressure of inspired oxygen, in millimeters of mercury; PaCO2 is the partial pressure of carbon dioxide in arterial blood, in millimeters of mercury; R is the respiratory quotient, which is 0.8.

[0086] In this embodiment, the initial infusion index is calculated according to the infusion evaluation index, an initial infusion index model is established according to the initial infusion index, and initial infusion information corresponding to the initial infusion index is output through the initial infusion index model, the initial infusion index includes an initial infusion volume index and an initial infusion flow rate index, the initial infusion index model includes an initial infusion volume index model and an initial infusion flow rate index model, and the initial infusion information includes initial infusion volume information and initial infusion flow rate information, which can be specifically implemented by the following steps:

[0087] S201: Establishing the initial infusion volume index model by calculating the initial infusion volume index based on the infusion evaluation index. The calculation formula of the initial infusion volume index is:

[0088]

[0089] Among them, f L is the initial infusion volume index; is rounded down; E is the altitude, in meters; is the gender index, with a value of 1 for females and 0.5 for males; FIO2 is the inspired oxygen concentration, in %; PIO2 is the inspired oxygen partial pressure, in mmHg; β is the age index, with a value of 0.1 for those under 14 years old, 0.8 for those between 14 and 60 years old, and 0.5 for those over 60 years old; PaO2 is the arterial oxygen partial pressure, in mmHg; SBP is the systolic blood pressure, in mmHg; DBP is the diastolic blood pressure, in mmHg; P is the pulse, in beats per minute; is the water vapor partial pressure in millimeters of mercury;

[0090] S202: Outputting the initial infusion volume information through the initial infusion volume index model, timely judging the patient's condition, administering medicine as needed, and achieving rapid and reasonable rescue of the patient, wherein the initial infusion volume information includes low initial infusion volume information and high initial infusion volume information;

[0091] Acquire an initial infusion volume threshold, and obtain the initial infusion volume information by comparing the initial infusion volume index with the initial infusion volume threshold;

[0092] Determine the initial infusion volume index, and when the initial infusion volume index is less than or equal to the initial infusion volume threshold, feedback the low initial infusion volume information, wherein the low initial infusion volume information is 65% of the maximum limit infusion volume of the therapeutic drug, in milliliters per day;

[0093] When the initial infusion volume index is greater than the initial infusion volume threshold, the high initial infusion volume information is fed back, and the high initial infusion volume information is 80% of the maximum limit infusion volume of the therapeutic drug, in milliliters per day;

[0094] S203: Establishing the initial infusion flow rate index model by calculating the initial infusion flow rate index based on the infusion evaluation index. The calculation formula of the initial infusion flow rate index is:

[0095]

[0096] Wherein, fv is the initial infusion flow rate index; To round down; is the gender index, with females taking 0.5 and males taking 1; β is the age index, with those under 14 taking 0.1, those aged 14 to 60 taking 0.5, and those aged 60 and above taking 0.8; t is the plateau exposure time in minutes; O is the respiratory rate in breaths per minute; PAPm is the mean pulmonary artery pressure in millimeters of mercury; T is the ambient temperature in degrees Celsius; PaO2 is the partial pressure of oxygen in arterial blood in millimeters of mercury;

[0097] S204: Outputting the initial infusion flow rate information according to the initial infusion flow rate index model, wherein the initial infusion flow rate information includes low initial infusion flow rate information and high initial infusion flow rate information;

[0098] Acquire an initial infusion flow rate threshold, and obtain the initial infusion flow rate information by comparing the initial infusion flow rate index with the initial infusion flow rate threshold;

[0099] Determine the initial infusion flow rate index, and when the initial infusion flow rate index is less than or equal to the initial infusion flow rate threshold, feedback the low initial infusion flow rate information, wherein the low initial infusion flow rate information is 65% of the maximum limit infusion flow rate of the therapeutic drug, in drops per minute;

[0100] When the initial infusion flow rate index is greater than the initial infusion flow rate threshold, the high initial infusion flow rate information is fed back, and the high initial infusion flow rate information is 80% of the maximum limit infusion flow rate of the therapeutic drug, in drops per minute.

[0101] In this embodiment, the appropriate infusion temperature, the real-time fluid loss of the human body, and the real-time fluid replacement volume of the human body are obtained according to the initial infusion information, and intelligent infusion control is performed. The intelligent infusion control includes an infusion heating operation and a loss-replenishment balance operation, which can be specifically implemented by the following steps:

[0102] S301: performing the infusion heating operation by an infusion heating device according to the initial infusion flow rate information;

[0103] S302: performing the loss-replenishment balance operation through an infusion clamp based on the real-time fluid loss and the real-time fluid replacement of the human body, wherein the real-time fluid replacement of the human body is the infusion volume that has been injected into the patient's body.

[0104] In this embodiment, the infusion heating operation is performed by an infusion heating device according to the initial infusion flow rate information, which can be specifically implemented by the following steps:

[0105] S301-1: Obtain the infusion liquid temperature through a temperature sensor, and calculate the appropriate infusion temperature according to the ambient temperature. The calculation formula is:

[0106] T max =6.1163×T-0.0187×V d -0.3125×T 2 +0.0051×T 3 -0.0001×V d 2

[0107] Among them, T max is the suitable temperature for infusion, in degrees Celsius; T is the ambient temperature, in degrees Celsius; V d is the initial infusion flow rate information, in drops per minute;

[0108] S301-2: Perform the infusion heating operation according to the suitable infusion temperature through the infusion heating device until the infusion liquid temperature reaches the suitable infusion temperature, thereby minimizing drug coagulation caused by too low a temperature or drug ineffectiveness caused by too high a temperature.

[0109] In this embodiment, the loss-replenishment balance operation is performed by an infusion clamp based on the real-time fluid loss and the real-time fluid replacement of the human body, wherein the real-time fluid replacement of the human body is the amount of infusion that has been infused into the patient's body, and can be specifically implemented by the following steps:

[0110] S302-1: Detect the patient's actual blood sodium concentration using a blood sodium concentration detection kit, and calculate the real-time fluid loss of the human body according to the patient's actual blood sodium concentration. The calculation formula is:

[0111] H=G×ξ(C' Na -C Na )

[0112] Among them, H is the real-time fluid loss of the human body, in ml; G is the body weight, in kilograms; ξ is the gender coefficient, which is 3 for females and 4 for males; C' Na The actual blood sodium concentration of the patient, in millimoles per liter; C Na Normal blood sodium concentration is 140 mmol per liter;

[0113] S302-2: obtaining fluid loss and replacement balance information based on the real-time fluid loss of the human body, wherein the fluid loss and replacement balance information includes fluid flow rate acceleration information and fluid flow rate reduction information;

[0114] Acquire the real-time fluid replenishment volume of the human body, and obtain the fluid loss-replenishment balance information by comparing the real-time fluid replenishment volume of the human body with the real-time fluid loss volume of the human body;

[0115] Determine the real-time fluid replenishment volume of the human body, and when the real-time fluid replenishment volume of the human body is less than the real-time fluid loss volume of the human body, feedback the information of accelerating the infusion flow rate;

[0116] When the real-time fluid replenishment volume of the human body is greater than or equal to the real-time fluid loss volume of the human body, the infusion flow rate slowing down information is fed back;

[0117] S302-3: Transmitting the fluid replacement balance information to the stepper motor, and the stepper motor performs the fluid replacement balance operation by controlling the infusion clamp.

[0118] In this embodiment, the fluid balance information is transmitted to the stepper motor, and the stepper motor controls the infusion clamp to perform the fluid balance operation, which can be specifically implemented by the following steps:

[0119] The fluid balance loss information is processed by an intermediate frequency filter to obtain an intermediate frequency fluid balance loss signal, and the intermediate frequency fluid balance loss signal is expressed as:

[0120]

[0121] Among them, S IF(t X ) is the medium frequency fluid balance loss signal; r is the fluid balance loss information; A IF is the amplitude of the intermediate frequency loss of fluid balance signal; f IF is the center frequency of the intermediate frequency loss of fluid balance signal; t X The duration of the information for loss of fluid balance; h is the initial phase of the intermediate frequency fluid balance loss signal; IF (t X ) is an intermediate frequency filter;

[0122] The intermediate frequency loss-of-replenishment balance signal is mixed by a local oscillator and a mixer to obtain a transmission loss-of-replenishment balance signal, and the expression of the transmission loss-of-replenishment balance signal is:

[0123]

[0124] Among them, S RF (t X ) is to send a signal of loss of fluid balance; S IF (t X ) is the intermediate frequency loss of fluid balance signal; A RF is the amplitude of the transmitted signal of loss of replenishment balance; f0 is the center frequency of the transmitted signal of loss of replenishment balance; f IF is the center frequency of the intermediate frequency loss of fluid balance signal; t X The duration of the information for loss of fluid balance; It is the initial phase of sending the signal of loss of fluid replenishment balance; h IF (t X ) is an intermediate frequency filter;

[0125] The stepper motor receives the transmitted fluid replacement balance signal to obtain a received fluid replacement balance signal, wherein the received fluid replacement balance signal includes the transmitted fluid replacement balance signal, noise, and interference signal. The received fluid replacement balance signal is expressed as:

[0126]

[0127] Among them, r(t X ) is to receive the signal of loss of fluid balance; t X S is the duration of fluid balance loss information; RF (t X ) is to send a signal of loss of fluid balance; n(t X ) is noise; i(t X ) is the interference signal; f IF is the center frequency of the intermediate frequency loss of fluid balance signal; It is the initial phase of the intermediate frequency loss of fluid balance signal;

[0128] The interference loss of fluid balance signal is obtained through the signal anti-interference network to obtain the loss of fluid balance signal after interference suppression, and the interference signal during the infusion process is eliminated to prevent the infusion device from triggering the termination of infusion information after receiving the interference signal. The expression of the loss of fluid balance signal after interference suppression is:

[0129] λ(t X )=r(t X )-r'(t X )

[0130] Among them, λ(t X ) is the signal of loss of fluid balance after interference suppression; r(t X ) receives the signal of loss of fluid balance; r'(t X ) is the interference signal of loss of fluid balance;

[0131] The stepper motor performs the fluid replacement balance operation by controlling the infusion clamp according to the interference suppressed fluid replacement balance signal.

[0132] An infusion control system based on loss of fluid replacement balance, comprising a data acquisition module, an initial infusion information output module, an intelligent infusion control module, and an intelligent infusion termination module;

[0133] The data acquisition module is used to obtain infusion evaluation indicators, which include environmental evaluation indicators and human evaluation indicators. The environmental evaluation indicators include atmospheric pressure, altitude, ambient temperature, atmospheric oxygen concentration, water vapor partial pressure, and oxygen flow. The human evaluation indicators include human health indicators and human oxygen content indicators. The human health indicators include systolic pressure, diastolic pressure, pulse, respiratory rate, gender index, gender coefficient, mean pulmonary artery pressure, age index, respiratory quotient, arterial carbon dioxide partial pressure, plateau exposure time, and body weight. The human oxygen content indicators include inspired oxygen concentration, inspired oxygen partial pressure, and arterial oxygen partial pressure.

[0134] The initial infusion information output module is used to calculate the initial infusion index according to the infusion evaluation index, establish an initial infusion index model according to the initial infusion index, and output the initial infusion information corresponding to the initial infusion index through the initial infusion index model, wherein the initial infusion index includes an initial infusion volume index and an initial infusion flow rate index, the initial infusion index model includes an initial infusion volume index model and an initial infusion flow rate index model, and the initial infusion information includes initial infusion volume information and initial infusion flow rate information;

[0135] The intelligent infusion control module is used to obtain the appropriate infusion temperature, the real-time human body fluid loss, and the real-time human body fluid replacement according to the initial infusion information and perform intelligent infusion control, wherein the intelligent infusion control includes an infusion heating operation and a loss-replenishment balance operation;

[0136] The intelligent infusion termination module is used to generate an infusion termination instruction when the real-time fluid replenishment volume of the human body is twice the real-time fluid loss volume of the human body, terminate the intelligent infusion control through the infusion termination instruction, and trigger the buzzer to sound an alarm.

[0137] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Although the present invention has been disclosed as a preferred embodiment as above, it is not used to limit the present invention. Any technical personnel in this field can make some changes or modify the technical contents disclosed above into equivalent embodiments without departing from the scope of the technical solution of the present invention. However, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention without departing from the content of the technical solution of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. A method for controlling infusion based on loss of fluid balance, characterized in that: The implementation of the infusion control method comprises the following steps: S1: Obtain infusion evaluation indicators, the infusion evaluation indicators include environmental evaluation indicators and human evaluation indicators, the human evaluation indicators include human health indicators and human oxygen content indicators, the environmental evaluation indicators include atmospheric pressure, altitude, ambient temperature, atmospheric oxygen concentration, water vapor partial pressure, and oxygen flow; the human health indicators include systolic blood pressure, diastolic blood pressure, pulse, respiratory rate, gender index, gender coefficient, pulmonary artery mean pressure, age index, respiratory quotient, arterial blood carbon dioxide partial pressure, plateau exposure time, and body weight; the human oxygen content indicators include inspired oxygen concentration, inspired oxygen partial pressure, and arterial blood oxygen partial pressure; S2: calculating an initial infusion index according to the infusion evaluation index, establishing an initial infusion index model according to the initial infusion index, and outputting initial infusion information corresponding to the initial infusion index through the initial infusion index model, wherein the initial infusion index includes an initial infusion volume index and an initial infusion flow rate index, the initial infusion index model includes an initial infusion volume index model and an initial infusion flow rate index model, and the initial infusion information includes initial infusion volume information and initial infusion flow rate information; S3: according to the initial infusion information, the appropriate infusion temperature, the real-time fluid loss of the human body, and the real-time fluid replacement volume of the human body are obtained, and intelligent infusion control is performed, wherein the intelligent infusion control includes an infusion heating operation and a loss-replenishment balance operation; S4: When the real-time fluid replenishment volume of the human body is twice the real-time fluid loss volume of the human body, an infusion termination instruction is generated, and the intelligent infusion control is terminated by the infusion termination instruction, and the buzzer is triggered to sound an alarm.

2. The infusion control method according to claim 1, characterized in that: The step S2 specifically includes: S201: Establishing the initial infusion volume index model by calculating the initial infusion volume index based on the infusion evaluation index. The calculation formula of the initial infusion volume index is: ， Among them, f L is the initial infusion volume index, is rounded down, E is the altitude, φ is the gender index, which is 1 for females and 0.5 for males, FIO2 is the fraction of inspired oxygen, PIO2 is the partial pressure of inspired oxygen, β is the age index, which is 0.1 for those under 14 years old, 0.8 for those between 14 and 60 years old, and 0.5 for those over 60 years old. is the partial pressure of oxygen in arterial blood, SBP is the systolic pressure, DBP is the diastolic pressure, P is the pulse, is the water vapor partial pressure; S202: Outputting the initial infusion volume information through the initial infusion volume index model, wherein the initial infusion volume information includes low initial infusion volume information and high initial infusion volume information; Acquire an initial infusion volume threshold, and obtain the initial infusion volume information by comparing the initial infusion volume index with the initial infusion volume threshold; Determine the initial infusion volume index, and when the initial infusion volume index is less than or equal to the initial infusion volume threshold, feed back the low initial infusion volume information, wherein the low initial infusion volume information is 65% of the maximum limit infusion volume of the therapeutic drug, in milliliters per day; When the initial infusion volume index is greater than the initial infusion volume threshold, the high initial infusion volume information is fed back, and the high initial infusion volume information is 80% of the maximum limit infusion volume of the therapeutic drug, in milliliters per day; S203: Establishing the initial infusion flow rate index model by calculating the initial infusion flow rate index based on the infusion evaluation index. The calculation formula of the initial infusion flow rate index is: ， Where, fv is the initial infusion flow rate index, is rounded down, φ is the gender index, with females taking 0.5 and males taking 1, β is the age index, with those under 14 taking 0.1, those between 14 and 60 taking 0.5, and those over 60 taking 0.8, t is the plateau exposure time, O is the respiratory rate, PAPm is the mean pulmonary artery pressure, T is the ambient temperature, is the partial pressure of oxygen in arterial blood; S204: Outputting the initial infusion flow rate information according to the initial infusion flow rate index model, wherein the initial infusion flow rate information includes low initial infusion flow rate information and high initial infusion flow rate information; Acquire an initial infusion flow rate threshold, and obtain the initial infusion flow rate information by comparing the initial infusion flow rate index with the initial infusion flow rate threshold; Determine the initial infusion flow rate index, and when the initial infusion flow rate index is less than or equal to the initial infusion flow rate threshold, feedback the low initial infusion flow rate information, wherein the low initial infusion flow rate information is 65% of the maximum limit infusion flow rate of the therapeutic drug, in drops per minute; When the initial infusion flow rate index is greater than the initial infusion flow rate threshold, the high initial infusion flow rate information is fed back, and the high initial infusion flow rate information is 80% of the maximum limited infusion flow rate of the therapeutic drug, in drops per minute.

3. The infusion control method according to claim 1, characterized in that: The step S3 specifically includes: S301: performing the infusion heating operation by an infusion heating device according to the initial infusion flow rate information; S302: performing the loss-replenishment balance operation through an infusion clamp based on the real-time fluid loss and the real-time fluid replacement of the human body, wherein the real-time fluid replacement of the human body is the infusion volume that has been injected into the patient's body.

4. The infusion control method according to claim 3, characterized in that: The step S301 specifically includes: S301-1: Obtain the infusion liquid temperature through a temperature sensor, and calculate the appropriate infusion temperature according to the ambient temperature. The calculation formula is: ， Among them, T max is the suitable temperature for infusion, T is the ambient temperature, V d is the initial infusion flow rate information; S301-2: Perform the infusion heating operation according to the suitable infusion temperature through the infusion heating device until the infusion liquid temperature reaches the suitable infusion temperature.

5. The infusion control method according to claim 3, characterized in that: The step S302 specifically includes: S302-1: Detect the patient's actual blood sodium concentration using a blood sodium concentration detection kit, and calculate the real-time fluid loss of the human body according to the patient's actual blood sodium concentration. The calculation formula is: H=G×ξ(C' Na -C Na ), Among them, H is the real-time fluid loss of the human body, G is the body weight, ξ is the gender coefficient, which is 3 for females and 4 for males, and C' Na The actual blood sodium concentration of the patient, C Na Normal blood sodium concentration is 140 mmol per liter; S302-2: obtaining fluid loss and replacement balance information based on the real-time fluid loss of the human body, wherein the fluid loss and replacement balance information includes fluid flow rate acceleration information and fluid flow rate reduction information; Acquire the real-time fluid replenishment volume of the human body, and obtain the fluid loss-replenishment balance information by comparing the real-time fluid replenishment volume of the human body with the real-time fluid loss volume of the human body; Determine the real-time fluid replenishment volume of the human body, and when the real-time fluid replenishment volume of the human body is less than the real-time fluid loss volume of the human body, feedback the information of accelerating the infusion flow rate; When the real-time fluid replenishment volume of the human body is greater than or equal to the real-time fluid loss volume of the human body, the infusion flow rate slowing down information is fed back; S302-3: Transmitting the fluid replacement balance information to the stepper motor, and the stepper motor performs the fluid replacement balance operation by controlling the infusion clamp.

6. The infusion control method according to claim 5, characterized in that: The step S302-3 specifically includes: The fluid balance loss information is processed by an intermediate frequency filter to obtain an intermediate frequency fluid balance loss signal, and the intermediate frequency fluid balance loss signal is expressed as: ， Among them, S IF (t X ) is the intermediate frequency fluid balance signal, r is the fluid balance information, A IF is the amplitude of the intermediate frequency loss of fluid balance signal, f IF is the center frequency of the intermediate frequency loss of fluid balance signal, t X is the duration of fluid balance loss information, φ IF is the initial phase of the intermediate frequency fluid balance signal, h IF (t X ) is an intermediate frequency filter; The intermediate frequency loss-of-replenishment balance signal is mixed by a local oscillator and a mixer to obtain a transmission loss-of-replenishment balance signal, and the transmission loss-of-replenishment balance signal is expressed as: ， Among them, S RF (t X ) is used to send a signal of loss of fluid balance, S IF (t X ) is the intermediate frequency loss of fluid balance signal, A RF is the amplitude of the transmitted signal of loss of replenishment balance, f0 is the center frequency of the transmitted signal of loss of replenishment balance, and f IF is the center frequency of the intermediate frequency loss of fluid balance signal, t X is the duration of fluid balance loss information, φ RF To send the initial phase of the signal of loss of fluid balance, h IF (t X ) is an intermediate frequency filter; The stepper motor receives the transmitted fluid replacement balance signal to obtain a received fluid replacement balance signal, wherein the received fluid replacement balance signal includes the transmitted fluid replacement balance signal, noise, and interference signal. The received fluid replacement balance signal is expressed as: r(t X )=[S RF (t X )+n(t X )+i(t X )]cos(2πf IF t X +φ IF ), Among them, r(t X ) is the signal of receiving fluid balance loss, t X is the duration of fluid balance loss information, S RF (t X ) is to send the signal of loss of fluid balance, n(t X ) is noise, i(t X ) is the interference signal, f IF is the center frequency of the intermediate frequency loss of fluid balance signal, φ IF It is the initial phase of the intermediate frequency loss of fluid balance signal; The interference loss of fluid replenishment balance signal is obtained through the signal anti-interference network to obtain the loss of fluid replenishment balance signal after interference suppression. The expression of the loss of fluid replenishment balance signal after interference suppression is: λ(t X )=r(t X )-r'(t X ), Among them, λ(t X ) is the signal of loss of fluid balance after interference suppression, r(t X ) receives the signal of loss of fluid balance, r'(t X ) is the interference signal of loss of fluid balance; The stepper motor performs the fluid replacement balance operation by controlling the infusion clamp according to the interference suppressed fluid replacement balance signal.

7. An infusion control system based on loss of fluid replacement balance, used to execute the infusion control method according to any one of claims 1 to 6, characterized in that: It includes a data acquisition module, an initial infusion information output module, an intelligent infusion control module, and an intelligent infusion termination module; The data acquisition module is used to obtain infusion evaluation indicators, which include environmental evaluation indicators and human evaluation indicators. The environmental evaluation indicators include atmospheric pressure, altitude, ambient temperature, atmospheric oxygen concentration, water vapor partial pressure, and oxygen flow. The human evaluation indicators include human health indicators and human oxygen content indicators. The human health indicators include systolic pressure, diastolic pressure, pulse, respiratory rate, gender index, gender coefficient, mean pulmonary artery pressure, age index, respiratory quotient, arterial carbon dioxide partial pressure, plateau exposure time, and body weight. The human oxygen content indicators include inspired oxygen concentration, inspired oxygen partial pressure, and arterial oxygen partial pressure. The initial infusion information output module is used to calculate the initial infusion index according to the infusion evaluation index, establish an initial infusion index model according to the initial infusion index, and output the initial infusion information corresponding to the initial infusion index through the initial infusion index model, wherein the initial infusion index includes an initial infusion volume index and an initial infusion flow rate index, the initial infusion index model includes an initial infusion volume index model and an initial infusion flow rate index model, and the initial infusion information includes initial infusion volume information and initial infusion flow rate information; The intelligent infusion control module is used to obtain the appropriate infusion temperature, the real-time human body fluid loss, and the real-time human body fluid replacement according to the initial infusion information and perform intelligent infusion control, wherein the intelligent infusion control includes an infusion heating operation and a loss-replenishment balance operation; The intelligent infusion termination module is used to generate an infusion termination instruction when the real-time fluid replenishment volume of the human body is twice the real-time fluid loss volume of the human body, terminate the intelligent infusion control through the infusion termination instruction, and trigger the buzzer to sound an alarm.

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