Experimental animal balance force training and measuring equipment

Abstract

The invention relates to the technical field of animal experiment equipment, in particular to experimental animal balance force training and measuring equipment which comprises a base and further comprises a first rotating device, a second rotating device, an animal plate, a light shield, a visual sensor and a controller. The second rotating device comprises an L-shaped mounting plate, a second servo motor and a second speed reducer, the animal plate comprises a bottom plate and a binding belt, the U-shaped track is driven to horizontally rotate on the base, so that an experimental animal bound on the bottom plate is driven to horizontally rotate on the base, and meanwhile, the experimental animal bound on the bottom plate can be driven to vertically rotate on the base, so that the animal plate is fixed on the base. Therefore, the anti-rotation dizziness capability of the experimental animal under the centrifugal condition can be measured, so that the real coordination capability of the experimental animal can be effectively measured, and the accuracy of data obtained by the animal balance experiment is further improved.

Description

Technical Field

[0001] The invention relates to the technical field of animal experimental equipment, and in particular to an experimental animal balance training and measurement device. Background Art

[0002] In the process of human medical research, the study of the human cerebellum is usually carried out through the study of animal coordination and balance abilities due to methodological and ethical limitations. Animal balance experiments are experiments used to detect the motor coordination and balance abilities of animals. Animal balance experiments are mostly used in medicine to study the coordination and balance abilities of animals.

[0003] Existing animal balance experiments mainly use simple measurement methods such as balance beams to measure the coordination and balance abilities of experimental animals. The balance abilities of experimental animals are measured by having the experimental animals crawl on the balance beam and enter a dark box.

[0004] However, the above-mentioned measurement method only measures the balance ability of experimental animals, but does not effectively measure the actual coordination ability of experimental animals, thereby reducing the accuracy of the data obtained from the animal balance experiment.

[0005] Anti-vertigo ability is an important indicator of coordination ability. The present application adopts a certain method to quantitatively measure the anti-vertigo ability of experimental animals, thereby being able to effectively measure the true coordination ability of experimental animals. Summary of the invention

[0006] The purpose of the present invention is to provide an experimental animal balance training and measurement device, which solves the technical problem that the existing animal balance experiment only measures the balance ability of the experimental animal when measuring with a simple measurement method such as a balance beam, but does not effectively measure the actual coordination ability of the experimental animal, thereby reducing the accuracy of the data obtained from the animal balance experiment.

[0007] To achieve the above-mentioned purpose, the present invention provides an experimental animal balance training and measurement equipment, comprising a base, a first rotating device, a second rotating device, an animal board, a light shield, a visual sensor and a controller; the first rotating device comprises a first servo motor, a first reducer and a U-shaped track, the first servo motor and the first reducer are both fixedly mounted on the base, the output shaft of the first servo motor is connected to the input shaft of the first reducer, and the U-shaped track is fixedly mounted on the output shaft of the first reducer; the second rotating device comprises an L-shaped mounting plate, a second servo motor and a second reducer, the L-shaped mounting plate is arranged on the U-shaped track, the second servo motor and the second reducer are both fixedly mounted on the L-shaped mounting plate, and the output shaft of the second servo motor is connected to the input shaft of the second reducer; the animal board comprises a bottom plate and a strap, the bottom plate is connected to the output shaft of the second reducer, and the strap is arranged on the bottom plate; the light shield is arranged on the base, and completely covers the first rotating device, the second rotating device and the animal board, the visual sensor is installed on the top of the light shield, the controller is respectively connected to the visual sensor, the first servo motor and the second servo motor, and the controller is located on the base.

[0008] Among them, a plurality of rows of threaded holes are arranged at the bottom of the U-shaped track, a through hole is arranged on the L-shaped mounting plate, and the L-shaped mounting plate is fixedly mounted on the U-shaped track by screws.

[0009] The strap has a Velcro sub-strip and a Velcro main strip, and the experimental animal can be fixed by sticking the Velcro sub-strip and the Velcro main strip together.

[0010] Among them, the experimental animal balance training and measurement equipment also includes a flexible display screen, which is arranged around the U-shaped track and tracks and displays a specific pattern in the direction of the animal's line of sight based on the animal's head direction obtained by the visual sensor.

[0011] Wherein, the experimental animal balance training and measurement equipment also includes a temperature control device, which is arranged in the light shield and is used to control the temperature in the experimental space.

[0012] Wherein, the experimental animal balance training and measurement equipment also includes a water spraying device, which is arranged above the animal plate and is used to implement specific water spraying stimulation to the experimental animal.

[0013] Wherein, the experimental animal balance training and measurement equipment also includes a host computer, which is connected to the controller and is used to set the rotation speed curves of the first rotating device and the second rotating device and the maximum experimental time.

[0014] The present invention provides an experimental animal balance training and measurement device. By driving the U-shaped track to rotate horizontally above the base, the L-shaped mounting plate can be driven to rotate horizontally above the base, and the experimental animal bound to the bottom plate can be driven to rotate horizontally above the base. By driving the bottom plate to rotate vertically on the L-shaped mounting plate, the experimental animal bound to the bottom plate can be driven to rotate vertically above the base. Combined with the horizontal rotation of the experimental animal above the base, the anti-rotational dizziness ability of the experimental animal under centrifugal conditions can be measured. During the rotation of the experimental animal, the visual sensor is used to collect the visual information formed in the experiment. The controller can obtain visual data and determine whether the experimental animal is dizzy based on the visual data. When dizziness occurs, the controller can be used to stop the rotation of the experimental animal to stop the entire experiment. By measuring the experimental animal's ability to resist rotation dizziness under centrifugal conditions, an effective measurement of the real coordination ability of the experimental animal can be achieved, thereby improving the accuracy of the data obtained from the animal balance experiment. This solves the technical problem that the existing animal balance experiment only measures the balance ability of the experimental animal when measuring with simple measurement methods such as balance beams, but does not effectively measure the real coordination ability of the experimental animal, thereby reducing the accuracy of the data obtained from the animal balance experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art are briefly introduced below.

[0016] Figure 1 It is a schematic diagram of the overall structure of the experimental animal balance training and measurement device according to the first embodiment of the present invention.

[0017] Figure 2 FIG. 4 is a cross-sectional schematic diagram along the first servo motor of the first embodiment of the present invention.

[0018] Figure 3 1 is a schematic cross-sectional view of a temperature control device according to a first embodiment of the present invention.

[0019] Figure 4 It is a schematic diagram of the connection between the U-shaped track and the L-shaped mounting plate according to the first embodiment of the present invention.

[0020] Figure 5 1 is a top view of the experimental animal balance training and measurement device according to the first embodiment of the present invention.

[0021] Figure 6 The first embodiment of the present invention Figure 5 Enlarged view of point A.

[0022] In the figure: 101-base, 102-light shield, 103-visual sensor, 104-controller, 105-flexible display screen, 106-temperature control device, 107-water spray device, 108-host computer, 109-first servo motor, 110-first reducer, 111-U-shaped track, 112-L-shaped mounting plate, 113-second servo motor, 114-second reducer, 115-bottom plate, 116-strap, 117-screw, 118-Velcro sub-sticker, 119-Velcro mother sticker. DETAILED DESCRIPTION

[0024] Embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, but should not be construed as limiting the present invention.

[0025] First embodiment: See also Figures 1 to 6 The present invention provides an experimental animal balance training and measurement device, including a base 101, a first rotating device, a second rotating device, an animal board, a light shield 102, a visual sensor 103, a controller 104, a flexible display screen 105, a temperature control device 106, a water spray device 107 and a host computer 108, the first rotating device includes a first servo motor 109, a first reducer 110 and a U-shaped track 111, the second rotating device includes an L-shaped mounting plate 112, a second servo motor 113 and a second reducer 114, and the animal board includes a bottom plate 115 and a strap 116.

[0026] In this embodiment, by driving the U-shaped track 111 to rotate horizontally above the base 101, the L-shaped mounting plate 112 can be driven to rotate horizontally above the base 101, and then the experimental animal bound to the bottom plate 115 can be driven to rotate horizontally above the base 101. By driving the bottom plate 115 to rotate vertically on the L-shaped mounting plate 112, the experimental animal bound to the bottom plate 115 can be driven to rotate vertically above the base 101. Combined with the horizontal rotation of the experimental animal above the base 101, the anti-rotational dizziness ability of the experimental animal under centrifugal conditions can be measured. During the rotation of the experimental animal, the visual sensor 10 3 is used to collect visual data formed by the experiment, and it is determined whether the experimental animal has dizziness based on the visual data. When dizziness occurs, the controller 104 is used to control the experimental animal to stop rotating, so as to stop the entire experiment. By measuring the anti-rotation dizziness ability of the experimental animal under centrifugal conditions, an effective measurement of the real coordination ability of the experimental animal is achieved, thereby improving the accuracy of the data obtained from the animal balance experiment, and solving the technical problem that the existing animal balance experiment only measures the balance ability of the experimental animal when measuring with a simple measurement method such as a balance beam, but does not effectively measure the real coordination ability of the experimental animal, thereby reducing the accuracy of the data obtained from the animal balance experiment.

[0027] Wherein, the first servo motor 109 and the first reducer 110 are both fixedly mounted on the base 101, the output shaft of the first servo motor 109 is connected to the input shaft of the first reducer 110, the U-shaped track 111 is fixedly mounted on the output shaft of the first reducer 110, the L-shaped mounting plate 112 is arranged on the U-shaped track 111, the second servo motor 113 and the second reducer 114 are both fixedly mounted on the L-shaped mounting plate 112, the output shaft of the second servo motor 113 is connected to the input shaft of the second reducer 114, the bottom plate 115 is connected to the output shaft of the second reducer 114, the binding belt 116 is arranged on the bottom plate 115, the shading The cover 102 is arranged on the base 101, and completely covers the first rotating device, the second rotating device and the animal plate. The visual sensor 103 is installed on the top of the light shielding cover 102. The controller 104 is connected to the visual sensor 103, the first servo motor 109 and the second servo motor 113 respectively. The controller 104 is located on the base 101. The output shaft of the first servo motor 109 is connected to the input shaft of the first reducer 110, and the U-shaped track 111 is fixedly installed on the output shaft of the first reducer 110, so that the first servo motor 109 can transmit the driving force to the input shaft of the first reducer 110, and the first servo motor 109 is connected to the input shaft of the first reducer 110. The driving force is decelerated, and after deceleration, the decelerated driving force is transmitted to the U-shaped track 111 through the output shaft of the first reducer 110, so that the U-shaped track 111 can be driven to rotate horizontally above the base 101 at a low speed, and the output shaft of the second servo motor 113 is connected to the input shaft of the second reducer 114, and the bottom plate 115 is fixedly installed on the output shaft of the second reducer 114, so that the second servo motor 113 can transmit the driving force to the input shaft of the second reducer 114, and decelerate the driving force at the second reducer 114, and after deceleration, the decelerated driving force is transmitted to the bottom plate 115 through the output shaft of the second reducer 114, so that the U-shaped track 111 can be driven to rotate horizontally above the base 101 at a low speed. The bottom plate 115 rotates vertically above the base 101, the strap 116 can fix the experimental animal on the bottom plate 115, the light shield 102 covers the entire training and measuring equipment, constructs a lightless environment for the experiment, and isolates the heat exchange between the experimental environment and the outside world. The controller 104 is connected to the visual sensor 103, the first servo motor 109 and the second servo motor 113 respectively. The visual sensor 103 (including infrared lighting) is installed on the top of the light shield 102, and its field of view can completely cover the experimental area. It is used to collect visual data formed by the experiment, and judge the direction of the experimental animal's head through machine learning, as well as whether the experimental animal vomits or closes its eyes for a long time during the experiment.If vomiting occurs and the eye closure time is higher than the limit, it is considered that the animal is dizzy. At this time, the judgment result is transmitted to the controller 104, so that the controller 104 will generate corresponding control instructions to control the first servo motor 109 and the second servo motor 113 to stop running, thereby stopping the experiment.

[0028] Secondly, the output shaft of the first servo motor 109 is connected to the input shaft of the first reducer 110 through a gear pair, and the second rotating device is electrically connected to the base 101 through a conductive slip ring.

[0029] Again, the bottom of the U-shaped track 111 is provided with multiple rows of threaded holes, the L-shaped mounting plate 112 is provided with through holes, the L-shaped mounting plate 112 is fixedly mounted on the U-shaped track 111 by screws 117, the U-shaped track 111 is composed of two U-shaped track plates, each U-shaped track plate is evenly distributed with an even number of threaded holes, the L-shaped mounting plate 112 is evenly distributed with through holes, the number of through holes of the L-shaped mounting plate 112 is the same as the number of threaded holes of each U-shaped track plate, and the positions of the through holes of the L-shaped mounting plate 112 are The screw 117 is threadedly connected to the threaded hole of the U-shaped track plate corresponding to the position of the threaded hole of each U-shaped track plate, so that the screw 117 can pass through the through hole of the L-shaped mounting plate 112 and be tightened in the threaded hole of the U-shaped track plate, so that the L-shaped mounting plate 112 is fixedly mounted on the U-shaped track plate, and the two L-shaped mounting plates 112 are fixedly mounted on the two U-shaped track plates respectively, so that the two L-shaped mounting plates 112 can be fixedly mounted on the left and right sides of the U-shaped track 111 respectively.

[0030] Meanwhile, the strap 116 is provided with a Velcro sub-strip 118 and a Velcro main patch 119 , and the experimental animal can be fixed by sticking the Velcro sub-strip 118 and the Velcro main patch 119 together.

[0031] In addition, the flexible display screen 105 is arranged around the U-shaped track 111, and based on the animal head orientation obtained by the visual sensor 103, tracks and displays a specific pattern in the direction of the animal's line of sight. The height of the highest point of the L-shaped mounting plate 112 should be higher than the height of the highest point of the base plate 115 to avoid blocking the line of sight of the experimental animal fixed on the base plate 115, which prevents the experimental animal from viewing the flexible display screen 105.

[0032] Finally, the temperature control device 106 is arranged in the light shield 102 for controlling the temperature in the experimental space, the water spray device 107 is arranged above the animal plate for implementing specific water spray stimulation to the experimental animals, and the host computer 108 is connected to the controller 104 for setting the rotation speed curve of the first rotating device and the second rotating device and the maximum experimental time.

[0033] When using an experimental animal balance training and measurement device of the present embodiment, when measuring the anti-rotational dizziness ability of the experimental animal, the abdomen of the experimental animal is first placed on the base plate 115, and the experimental animal is fixed by sticking the Velcro sub-strip 118 on the strap 116 and the Velcro mother patch 119 on another strap 116 together, and the sticking position of the Velcro sub-strip 118 and the Velcro mother patch 119 on the strap 116 is adjusted, so that experimental animals of different specifications can be fixed.

[0034] After the experimental animal is fixed, the light shield 102 is covered on the base 101, so that the light shield 102 can construct a light-free environment for the experiment and isolate the heat exchange between the experimental environment and the outside world. After that, after setting the rotation speed curve of the first rotating device and the second rotating device and the maximum experimental time through the host computer 108, a start instruction is input to the host computer 108, so that the host computer 108 can transmit the start instruction to the controller 104, so that the controller 104 can control the start of the first servo motor 109 and the second servo motor 113 according to the start instruction.

[0035] By starting the first servo motor 109, the first servo motor 109 can transmit the driving force to the input shaft of the first reducer 110, and reduce the driving force at the first reducer 110. After reduction, the reduced driving force is transmitted to the U-shaped track 111 through the output shaft of the first reducer 110, so that the U-shaped track 111 can be driven to rotate horizontally above the base 101 at a low speed, and then the experimental animal bound to the bottom plate 115 can be driven to rotate horizontally above the base 101 at a low speed. The start-up of the motor 113 enables the second servo motor 113 to transmit the driving force to the input shaft of the second reducer 114, and reduce the driving force at the second reducer 114. After reduction in speed, the reduced driving force is transmitted to the base plate 115 through the output shaft of the second reducer 114, thereby driving the experimental animal bound to the base plate 115 to rotate vertically above the base 101 at a low speed. Combined with the horizontal rotation of the experimental animal above the base 101, the anti-rotational dizziness ability of the experimental animal under centrifugal conditions can be measured.

[0036] During the measurement of the experimental animals' ability to resist rotational dizziness, the temperature in the experimental space is controlled by the temperature control device 106, the water spray device 107 is used to apply specific water spray stimulation to the experimental animals, the visual data formed by the experiment is collected by the visual sensor 103, and the direction of the experimental animal's head and whether the experimental animal vomits or closes its eyes for a long time during the experiment are determined by machine learning. If vomiting occurs and the eye-closing time is higher than the limit, it is considered that the animal is dizzy. At this time, the judgment result is transmitted to the controller 104, so that the controller 104 will generate corresponding control instructions to control the first servo motor 109 and the second servo motor 113 to stop running, thereby stopping the experiment. The flexible display screen 105 tracks and displays a specific pattern in the direction of the animal's line of sight based on the animal's head direction obtained by the visual sensor 103, thereby assisting in measuring the experimental animals' ability to resist rotational dizziness under centrifugal conditions.

[0037] By measuring the ability of experimental animals to resist rotational dizziness under centrifugal conditions, the actual coordination ability of experimental animals can be effectively measured, thereby improving the accuracy of data obtained from animal balance experiments. This solves the technical problem that the existing animal balance experiments, when using simple measurement methods such as balance beams, only measure the balance ability of experimental animals, but fail to effectively measure the actual coordination ability of experimental animals, thereby reducing the accuracy of data obtained from animal balance experiments.

[0038] What is disclosed above is only one or more preferred embodiments of the present application, and cannot be used to limit the scope of rights of the present application. Ordinary technicians in this field can understand that all or part of the processes of implementing the above embodiments and equivalent changes made according to the claims of the present application are still within the scope covered by the present application.

Claims

1. An experimental animal balance training and measurement device, comprising a base, characterized in that: Also included are a first rotating device, a second rotating device, an animal plate, a light shield, a visual sensor, and a controller; The first rotating device comprises a first servo motor, a first reducer and a U-shaped track, wherein the first servo motor and the first reducer are both fixedly mounted on the base, the output shaft of the first servo motor is connected to the input shaft of the first reducer, and the U-shaped track is fixedly mounted on the output shaft of the first reducer; The second rotating device comprises an L-shaped mounting plate, a second servo motor and a second reducer, wherein the L-shaped mounting plate is arranged on the U-shaped track, the second servo motor and the second reducer are both fixedly mounted on the L-shaped mounting plate, and the output shaft of the second servo motor is connected to the input shaft of the second reducer; The animal board comprises a bottom plate and a strap, wherein the bottom plate is connected to the output shaft of the second reducer, and the strap is arranged on the bottom plate; The light shield is arranged on the base, completely covering the first rotating device, the second rotating device and the animal plate. The visual sensor is installed on the top of the light shield. The controller is respectively connected to the visual sensor, the first servo motor and the second servo motor, and the controller is located on the base.

2. The experimental animal balance training and measurement device according to claim 1, characterized in that: The bottom of the U-shaped track is provided with multiple rows of threaded holes, the L-shaped mounting plate is provided with through holes, and the L-shaped mounting plate is fixedly mounted on the U-shaped track by screws.

3. The experimental animal balance training and measurement device according to claim 1, characterized in that: The strap is provided with a Velcro sub-stick and a Velcro main stick, and the experimental animal is fixed by sticking the Velcro sub-stick and the Velcro main stick together.

4. The experimental animal balance training and measurement device according to claim 1, characterized in that: The experimental animal balance training and measurement equipment also includes a flexible display screen, which is arranged around the U-shaped track and tracks and displays a specific pattern in the direction of the animal's line of sight based on the animal's head direction obtained by the visual sensor.

5. The experimental animal balance training and measurement device according to claim 1, characterized in that: The experimental animal balance training and measurement equipment also includes a temperature control device, which is arranged in the light shield and is used to control the temperature in the experimental space.

6. The experimental animal balance training and measurement device according to claim 1, characterized in that: The experimental animal balance training and measurement equipment also includes a water spray device, which is arranged above the animal plate and is used to implement specific water spray stimulation to the experimental animal.

7. The experimental animal balance training and measurement device according to claim 1, characterized in that: The experimental animal balance training and measurement equipment also includes a host computer, which is connected to the controller and is used to set the rotation speed curves of the first rotating device and the second rotating device and the maximum experimental time.

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