Multi-angle non-isocenter irradiation bidirectional scanning particle therapy system

Abstract

A multi-angle non-isocenter irradiation bidirectional scanning particle therapy system comprises a rotating rack (1), two rectangular clamping plates (1-1) are connected with a rotating mechanism A (4) through a bracket (1-10), the rotating mechanism A (4) is further connected with a deflection magnet B (5) and a 90-degree deflection magnet C (6) which can achieve scanning in the Y direction, a rotating mechanism B (7) is installed on the outer surface of a front disc (1-2), and the rotating mechanism B (7) is connected with the bracket (1-10). The rotating mechanism A (4) is connected with the rotating mechanism B (7), the rotating mechanism B (7) is connected with a treatment bed (8), the rotating mechanism A (4) and the rotating mechanism B (7) are located above and below an XY plane, the axial leads of the rotating mechanism A (4) and the rotating mechanism B (7) are located in a YZ plane and are parallel to the Y axis, and therefore multi-angle irradiation under non-isocenter irradiation can be achieved, and bidirectional scanning can be conducted through a one-way deflection magnet.

Description

Technical Field

[0001] The present invention relates to particle radiotherapy, in particular to multi-angle rotational irradiation therapy, and is limited to the field of scanning irradiation therapy. The particles may be light ions such as protons or heavy ions such as carbon ions. Background Art

[0002] The currently commonly used single-rotating-axis multi-angle irradiation therapy system is bulky and expensive, which is one of the important reasons for the high cost of particle therapy.

[0003] There are several ways to reduce the size of a rotating rack.

[0004] The consensus is currently on superconducting technology. In the superconducting state, the current of the excitation coil can be very large, which can excite a very strong magnetic field. When the highest energy of the particle is determined, the magnetic stiffness is also determined. For a certain magnetic stiffness, the stronger the magnetic field, the smaller the deflection radius of the magnet. In this way, the multiple deflection magnets in the rotating frame can be made very small, and the volume of the rotating frame can be reduced. However, there are many difficulties in providing low-temperature refrigeration for the magnet excitation coil in the rotating state, especially when using liquid refrigerants, the operation of the refrigerator is limited by direction.

[0005] By reducing the diameter of the rotating gantry, the non-isocentric irradiation method can also be used, that is, the irradiation center of the tumor is not on the axis of the rotating gantry, but is located on the side opposite to the virtual point light source relative to the axis of rotation of the gantry.

[0006] Another method to reduce the size of the rotating gantry is to reduce the gap between the deflection magnet poles, which can greatly increase the magnetic induction intensity between the poles, in exchange for a reduction in the magnet deflection radius. However, after adopting this method, the possibility of installing a deflection magnet before the last deflection magnet to scan in a direction perpendicular to the axis of rotation of the rotating gantry is lost. There are two methods to perform scanning in a direction perpendicular to the axis of rotation of the rotating gantry: one is to install an independent bidirectional scanning system after the last deflection magnet, but this will increase the diameter of the rotating gantry, partially offsetting the reduction in the diameter of the gantry brought about by reducing the gap between the poles; the other is to achieve this by moving the treatment bed. However, the movement speed of the treatment bed should not be too fast, which will greatly increase the scanning irradiation time.

[0007] The present invention proposes to use a combination of non-isocentric irradiation and reducing the deflection magnet pole gap, and at the same time use a method of swinging the last deflection magnet to achieve scanning in a direction perpendicular to the rotating axis of the rotating frame. Summary of the invention

[0008] Aiming at the problem that the current rotating rack-style particle radiation therapy system is bulky, the present invention provides a particle therapy system with a small volume and capable of realizing multi-angle non-isocentric irradiation and bidirectional scanning.

[0009] The technical solution adopted by the present invention to achieve its technical purpose is to narrow the pole gap of the deflection magnet to reduce the volume of the deflection magnet, use non-isocentric irradiation to further reduce the diameter of the rotating frame, and use a swinging unidirectional scanning magnet to achieve bidirectional scanning. The main contents are: A rotating frame is set up, in which two rectangular clamps, in an initial state, refer to a rectangular coordinate system composed of an X-axis, a Y-axis and a Z-axis and can rotate with the rotating frame with the Y-axis as the axis, the upper and lower end faces are parallel to the XY plane, the front and rear end faces are parallel to the XZ plane, and the whole is mirror-symmetrical with respect to the XY plane and the YZ plane respectively, the front end face is connected to a front disc with a trapezoidal convex roller, the rear end face is connected to a rear disc with a flat roller, the center of the front disc and the rear disc coincide with the Y-axis, the two arc-shaped support plates are respectively connected to the outer side faces of the two rectangular clamps and the inner side faces of the front disc and the rear disc, the front disc falls on two supports A with trapezoidal concave rollers, the rear disc falls on two supports B with flat rollers, one of the supports B is connected to a rotating drive mechanism, the bottom faces of the two supports A and the two supports B are connected to a base, and the inner side faces of the two rectangular clamps are connected to a counterweight located below the XY plane.

[0010] Furthermore, two deflection magnets A are provided, connected to the inner side surfaces of the two rectangular clamping plates via two groups of two brackets A in each group, and are located close to the rear disc. The magnetic pole surfaces of the two magnetic poles A of each deflection magnet A are mirror-symmetrical with respect to the YZ plane. The two deflection magnets A have the same shape, the same structure, the same deflection angle, and opposite deflection directions, so that the particle beam E emitted from the second deflection magnet A is parallel to the particle beam A incident on the first deflection magnet A along the Y axis toward the origin of the rectangular coordinate system, is located above the XY plane, coincides with the YZ plane, and points to the XZ plane.

[0011] Furthermore, a range shifter is provided, which is connected to the inner side surfaces of the two rectangular clamping plates via a group of two brackets B and is located between the second deflection magnet A and the coordinate origin, and is used to adjust the energy of the particle beam E.

[0012] Furthermore, a rotating mechanism A is provided, which is connected to the inner side surfaces of the two rectangular clamping plates via a set of two rectangular plate brackets C, and whose length in the Y-axis direction spans the XZ plane, and whose rotation axis coincides with the axis line of the particle beam E.

[0013] Furthermore, a deflection magnet B is provided, connected to the rotating mechanism A from the direction where the rear disk is located, and the magnetic pole surfaces of the two magnetic poles B are mirror-symmetrical with respect to the YZ plane.

[0014] Furthermore, a 90° deflection magnet C is provided, connected to the rotating mechanism A from the direction where the front disk is located, and the magnetic pole surfaces of the two magnetic poles C are mirror-symmetrical with respect to the YZ plane.

[0015] Furthermore, a rotating mechanism B is provided, connected to the outer side surface of the front disc, and its rotation axis is parallel to the Y axis, within the YZ plane, and below the XY plane.

[0016] Furthermore, a treatment bed is provided and connected to the rotating mechanism B.

[0017] Furthermore, a CBCT image positioning system is provided and connected to the inner side of the front disk, and the axis lines of the two positioning diamond beams are in the XZ plane and perpendicularly intersect the axis line of the rotating mechanism B.

[0018] Under the above arrangement, the multi-angle irradiation and bidirectional scanning of the three-rotation axis particle therapy system are completed by the treatment bed, the rotating frame, the rotating mechanism B, the CBCT image positioning system, two deflection magnets A, the deflection magnet B, the 90° deflection magnet C, the rotating mechanism A and the range shifter. Their functions are: The patient is positioned on the treatment couch; The rotating gantry rotates to determine the irradiation angle; The rotating mechanism B rotates in the opposite direction with respect to the rotating frame at equal angles, so that the bed board of the treatment bed is always kept horizontal; The CBCT image positioning system is responsible for determining the collimation parameters; The treatment bed is responsible for delivering the tumor target to the treatment center located at the intersection of the rotation axis of the rotating mechanism B and the XZ plane; The two deflection magnets A2 are responsible for radially translating the particle beams A with different energies incident along the Y axis to a specified distance in the YZ plane, and transforming them into particle beams E pointing to the XZ plane.

[0019] The deflection magnet B and the 90° deflection magnet C are responsible for scanning in the Y-axis direction, and make the particle beam I emitted from the 90° deflection magnet C parallel to each other, intersect the Y-axis perpendicularly, and cover the coordinate origin; The rotating mechanism A is responsible for scanning in the X-axis direction, so that the particle beam I emitted from the 90° deflection magnet C scans the coordinate origin and the treatment center, and the reverse extension line of the axis of the particle beam I is perpendicular to the rotation axis of the rotating mechanism A; The range shifter changes the range of particle beam I in the patient's body by changing the energy of particle beam E, so that bidirectional scanning can be performed at different depths of the tumor target area.

[0020] The three-rotation-axis multi-angle irradiation bidirectional scanning particle therapy system arranged as above can realize multi-angle irradiation under non-isocentric irradiation and realize bidirectional scanning using a unidirectional scanning magnet. The non-isocentric irradiation and the method of reducing the magnetic pole gap used therein can greatly reduce the volume of the rotating gantry without using superconducting technology. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 , Rotating rack structure diagram Figure 2 , Magnet layout Figure 3 、CBCT image positioning system location map Figure 4 , Determine the irradiation angle diagram Figure 5 , Scanning particle beam path diagram in YZ plane Figure 6 , Scanning particle beam path diagram in XZ plane Figure 7 , Structure diagram of rotating mechanism A (Part 1) Figure 8 2. Structure diagram of rotating mechanism A Fig. 9 , Structure diagram of rotating mechanism B Symbols in the figure: 0. The origin of the X-axis, Y-axis, and Z-axis rectangular coordinate system 1. A rotating rack 1-1. Two rectangular splints 1-2, front disc 1-3, rear disc 1-4. Two arc-shaped support plates 1-5. Two supports A 1-6. Two supports B 1-7. A rotary drive mechanism 1-8. A base 1-9. Counterweight 1-10. Bracket 1-10-1, two groups, two brackets A each 1-10-2, a set of two brackets B 1-10-3, two rectangular plate brackets C 2. Two deflection magnets A 2-1. Two magnetic poles A (2-1) 3. A range shifter 4. A rotating mechanism A 4-1. Two swivel support shafts A 4-2. Two rectangular plates 4-3. A rectangular frame 4-4, a turbine 4-5. A worm gear 4-6. Two bearings A 4-7. Two bearing seats A 4-8. A motor A 4-9. A counterweight 5. A deflection magnet B, 5-1. Two magnetic poles B 6. A 90° deflection magnet C 6-1. Two magnetic poles C 7. A rotating mechanism B 7-1. A swing support shaft B 7-2. A belt 7-3. Two limiting rollers 7-4. A small pulley 7-5. One axis 7-6, a set of bearings B 7-7. A bearing seat B 7-8. A U-shaped seat 7-9. A motor B 8. A treatment bed 8-1. Bed board of treatment bed 9. A CBCT image positioning system 9-1. Two positioning diamond beams 100. Particle beam A incident on the first deflection magnet A along the Y axis 200. The particle beam B deflected in the first deflection magnet A 300. Particle beam C emitted from the first deflection magnet A 400. The particle beam D deflected in the second deflection magnet A 500. Particle beam E emitted from the second deflection magnet A 600. Particle beam F deflected in deflection magnet B 700. Particle beam G emitted from deflection magnet B Particle beam H deflected in 800, 90° deflection magnet C 900, particle beam I emitted from 90° deflection magnet C 1000. Rotation axis of rotating mechanism B 2000, Treatment Center DETAILED DESCRIPTION

[0022] In order to simplify the description and make the features of the present invention clear and easy to understand, reference is made to a rectangular coordinate system consisting of an X-axis, a Y-axis and a Z-axis to indicate the orientation of the components based on the drawings. The rectangular coordinate system can be rotated with the present embodiment about the Y-axis as the axis, and when indicating the orientation of the components, the specific embodiment of the present invention is in an initial state.

[0023] The specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. Without violating the scope of the present invention, the present invention is not limited by the specific embodiments disclosed below.

[0024] This embodiment is a multi-angle non-isocentric irradiation bidirectional scanning particle therapy system like Figure 1 As shown, this embodiment includes a rotating frame 1. In the initial state, the two rectangular clamping plates 1-1 therein have their upper and lower end faces parallel to the XY plane, and the front and rear end faces are parallel to the XZ plane. The whole is mirror-symmetrical relative to the XY plane and the YZ plane respectively. The front end face is connected to the front disk 1-2 with a trapezoidal convex roller, and the rear end face is connected to the rear disk 1-3 with a flat roller. The centers of the front disk 1-2 and the rear disk 1-3 coincide with the Y axis. The two arc-shaped support plates 1-4 are respectively connected to the outer side surfaces of the two rectangular clamping plates 1-1 and the inner side surfaces of the front disk 1-2 and the rear disk 1-3. The front disk 1-2 falls on two supports A1-5 with trapezoidal concave rollers.

[0025] The trapezoidal convex roller of the front disc 1-2 cooperates with the trapezoidal concave roller of the support A1-5 to limit the displacement in the Y-axis direction of the roller composed of the front disc 1-2, the rear disc 1-3, the two rectangular clamping plates 1-1 and the two arc-shaped support plates 1-4.

[0026] like Figure 1 As shown, the rear disc 1-3 falls on two supports B1-6 with flat rollers, one of which is connected to a rotation drive mechanism 1-7, the bottom surfaces of the two supports A1-5 and the two supports B1-6 are connected to a base 1-8, and the inner sides of the two rectangular clamps 1-1 are connected to a counterweight 1-9 located below the XY plane.

[0027] Figure 1 In the middle, weights 1-9 are not visible.

[0028] like Figure 2 and Figure 5As shown, this embodiment also includes two deflection magnets A2, which are connected to the inner side surfaces of the two rectangular clamps 1-1 through two groups of two brackets A1-10-1 in each group, and are located close to the rear disk 1-3. The pole surfaces of the two poles 2-1 of each deflection magnet 2 are mirror-symmetrical with respect to the YZ plane. The two deflection magnets 2 have the same shape, the same structure, the same deflection angle, and opposite deflection directions, so that the particle beam E500 emitted from the second deflection magnet 2 is parallel to the particle beam A100 incident on the first deflection magnet 2 along the Y axis toward the coordinate origin 0 of the rectangular coordinate system, is located above the XY plane, coincides with the YZ plane, and points to the XZ plane.

[0029] like Figure 2 As shown, this embodiment also includes a range shifter 3, which is connected to the inner side surfaces of the two rectangular clamps 1-1 via a group of two brackets B1-10-2, and is located between the second deflection magnet 2 and the coordinate origin (0), and is used to adjust the energy of the particle beam E500.

[0030] Configuration of the range shifter 3 shows that this application example is used in conjunction with a cyclotron particle accelerator with non-adjustable energy. If it is used in conjunction with a synchrotron particle accelerator with adjustable energy, the range shifter 3 can be omitted.

[0031] Figure 2 In the embodiment, there are several components between the second deflection magnet A2 and the range shifter 3, which are a group of focusing magnets, a bidirectional guide magnet and an ionization chamber for detecting the cross section and axial position of the particle beam E500. They are necessary for the treatment system, but are not helpful in describing the function of this embodiment, so they are not mentioned in the claims.

[0032] like Figure 2 and Figure 5 As shown, this embodiment also includes a rotating mechanism A4, which is connected to the inner side surfaces of the two rectangular clamps 1-1 via a set of two rectangular plate brackets C1-10-3, and its length in the Y-axis direction spans the XZ plane, and its rotation axis coincides with the axis line of the particle beam E500.

[0033] like Figure 2 and Figure 5 As shown, this embodiment also includes a deflection magnet B5, which is connected to the rotating mechanism A4 from the direction where the rear disk 1-3 is located, and the pole surfaces of its two poles B5-1 are mirror-symmetric relative to the YZ plane.

[0034] like Figure 2 and Figure 5 As shown, this embodiment also includes a 90° deflection magnet C6 connected to the rotating mechanism A4, and the pole surfaces of its two poles C6-1 are mirror-symmetric relative to the YZ plane.

[0035] like Figure 2 and Figure 7As shown, in order to see the 90° deflection magnet C6, the rectangular frame 4-3 of the rotating mechanism A4 is cross-sectioned.

[0036] like Figure 1 As shown, this embodiment also includes a rotating mechanism B7 connected to the outer side of the front disk 1-2, and its rotation axis 1000 is parallel to the Y axis, within the YZ plane, and below the XY plane.

[0037] like Figure 1 As shown, this embodiment also includes a treatment bed 8 connected to the rotating mechanism B7.

[0038] like Figure 3 As shown, this embodiment also includes a CBCT image positioning system 9, which is connected to the inner side of the front disk 1-2, and the axis lines of its two positioning diamond beams 9-1 are in the XZ plane and perpendicularly intersect the rotation axis 1000 of the rotating mechanism B7.

[0039] The multi-angle irradiation and bidirectional scanning of the three-rotation axis particle therapy system are completed by the treatment bed 8, the rotating frame 1, the rotating mechanism B7, the CBCT image positioning system 9, two deflection magnets A2, the deflection magnet B5, the 90° deflection magnet C6, the rotating mechanism A4 and the range shifter 3. Their functions are as follows: Patients in Figure 1 The treatment couch 8 is shown positioned thereon.

[0040] like Figure 4 As shown, the rotating gantry 1 rotates to determine the irradiation angle.

[0041] like Figure 4 As shown, the rotating mechanism B7 rotates in the opposite direction with respect to the rotating frame 1 at equal angles, so that the bed plate 8-1 of the treatment bed 8 is always kept horizontal.

[0042] The CBCT image positioning system 9 is responsible for determining the collimation parameters.

[0043] like Figure 1 and Figure 6 As shown, the treatment bed 8 is responsible for delivering the tumor target center to the treatment center 2000 located at the intersection of the rotation axis 1000 of the rotating mechanism B7 and the XZ plane.

[0044] like Figure 5 As shown, the two deflection magnets A2 are responsible for radially translating the particle beams A100 incident along the Y axis with different energies to a specified distance in the YZ plane, and transforming them into the particle beams E500 pointing to the XZ plane. Since the specified translation distance is fixed, the two deflection magnets A2 need to change the magnetic induction intensity of the deflected particle beams B200 and D400 corresponding to the particle beams A100 with different energies.

[0045] like Figure 5 As shown, the deflection magnet B5 and the 90° deflection magnet C6 are responsible for scanning in the Y-axis direction, and make the particle beam I900 emitted from the 90° scanning magnet 6 parallel to each other, perpendicular to and intersecting the Y-axis, and covering the coordinate origin 0.

[0046] The scanning particle beam in the figure is composed of the following particle beam line segments connected tangentially at the boundary of the magnetic pole: The particle beam A100 is incident on the first deflection magnet A along the Y axis. The particle beam B200 is deflected in the first deflection magnet A. Particle beam C300 emitted from the first deflection magnet A Particle beam D400 deflected in the second deflection magnet A Particle beam E500 emitted from the second deflection magnet A Particle beam F600 deflected in deflection magnet B Particle beam G700 emitted from deflection magnet B Particle beam H800 deflected in 90° deflection magnet C Particle beam I900 emitted from 90° deflection magnet C The particle beam deflected in the deflection magnet B and the 90° deflection magnet C is not one line, which means that the deflection magnet B and the 90° deflection magnet C jointly participate in the scanning, so that the particle beams I900 emitted from the 90° scanning magnet 6 can be parallel to each other, which is equivalent to pushing the virtual point light source to infinity, thereby maximizing the focus-to-skin ratio.

[0047] like Figure 6 As shown, the rotating mechanism A4 is responsible for scanning in the X direction, so that the particle beam I900 emitted from the 90° scanning magnet 6 swings around the axis of the rotating mechanism A4, sweeping through the coordinate origin 0 and the treatment center 2000. At this time, the particle beam I900 is no longer perpendicular to the Y axis, but parallel to the XZ plane, and the direction extension line of the axis of the particle beam I900 is perpendicular to the rotation axis of the rotating mechanism A4.

[0048] Figure 6 In the figure, the rotating mechanism A4 is schematically represented by a rotating support shaft A4-1 as a component thereof.

[0049] like Figure 6 As shown, the distance from the virtual point light source located at the rotation axis of the rotating mechanism A4 to the irradiation center 2000 is limited and difficult to increase further, which reduces the focus-to-skin ratio of the X-axis scanning. This is why in the Y-axis scanning, the deflection magnet B is added to make the scanning particle beams I900 parallel to each other, so that the focus-to-skin ratio is increased to the maximum to neutralize the low focus-to-skin ratio of the X-axis scanning.

[0050] like Figure 5As shown, the range shifter 3 changes the range of the particle beam I900 in the patient's body by changing the energy of the particle beam E500, so that bidirectional scanning is performed at different depth levels of the tumor target area.

[0051] The particle therapy system with three rotating axes arranged as above realizes non-isocentric multi-angle irradiation through the cooperation of the rotating gantry 1 and the rotating mechanism B7; through the cooperation of the rotating mechanism A4, bidirectional scanning in the Y-axis and X-axis directions is realized with only a set of scanning magnets consisting of the deflection magnet B5 and the 90° deflection magnet C6. Since the deflection magnet B5 and the 90° deflection magnet C6 are only responsible for unidirectional scanning, the magnetic pole gap can be made very narrow, the magnetic induction intensity is very strong, the deflection radius can be very small, and the corresponding volume is also very small. Non-isocentric irradiation further reduces the radius of the rotating gantry 1. The overall effect is that the radius of the rotating gantry 1 can be shortened a lot without using superconducting technology.

[0052] like Figure 7 As shown, the rotating mechanism A4 includes two swiveling support shafts A4-1 whose axis lines coincide with the axis line of the particle beam E500, the inner rings of the two swiveling support shafts A4-1 are respectively connected to the inner side surfaces of two rectangular plate brackets C1-10-3 facing each other, the outer rings of the two swiveling support shafts A4-1 are respectively connected to a rectangular plate 4-2, the two rectangular plates 4-2 are connected to a rectangular frame 4-3, a 90° deflection magnet C6 is installed in the rectangular frame 4-3, and relative to the XZ plane, it is located on one side of the rear disk 1-3, and the surface of the rectangular plate 4-2 facing the rear disk 1-3 is connected to the deflection magnet B5.

[0053] Figure 7 In the figure, the two rectangular clamping plates 1-1 connected to the two rectangular plate brackets C1-10-3 are hidden.

[0054] like Figure 8 As shown, relative to the XZ plane, a turbine 4-4 is machined on the outer ring of the rotary support shaft A4-1 located on one side of the rear disc 1-3 toward the XY plane, and a worm 4-5 whose axis is parallel to the X-axis is movably connected to the turbine 4-4. The worm 4-5 passes through two rectangular clamps 1-1 and is connected to two bearings A4-6. Each bearing A4-6 is embedded in a bearing seat A4-7. The two bearing seats A4-7 are respectively connected to the outer side surfaces of the two rectangular clamps 1-1. The outer side surface of a bearing seat A4-7 is connected to a motor A4-8, and the rotating shaft of the motor A4-8 is connected to the worm 4-5.

[0055] Figure 8 In the figure, two rectangular clamping plates 1-1 connected to two bearing seats A4-7 are hidden.

[0056] like Figure 7As shown, a counterweight 4-9 is installed above the rectangular frame 4-3, so that the center of gravity of the rotating mechanism A4 together with the deflection magnet B5 and the 90° deflection magnet C6 connected thereto is on the rotation axis of the rotating mechanism A4. In this way, when the motor A4-8 drives the rotating mechanism A4 together with the deflection magnet B5 and the 90° deflection magnet C6 to rotate, it only needs to overcome their static mass, but not the static moment. The power of the motor A4-8 is required to be large enough so that the speed of scanning in the X direction is fast enough.

[0057] like Fig. 9 As shown, the rotating mechanism B7 includes a swivel support shaft B7-1, whose inner ring is connected to the outer side surface of the front disk 1-2, and whose rotation axis 1000 is parallel to the Y axis, within the YZ plane, and below the XY plane. The outer edge of the outer ring of the swivel support shaft B7-1 is processed into a pulley structure, which is movably connected to the belt 7-2. The belt 7-2 is movably connected to a small pulley 7-4 after passing through two limiting rollers 7-3. The small pulley 7-4 is connected to a shaft 7-5. The shaft 7-5 is movably connected to a group of bearings B7-6. The group of bearings B7-6 is embedded in a bearing seat B7-7. The bearing seat B7-7 -7 is connected to a U-shaped seat 7-8, the U-shaped seat 7-8 crosses the belt 7-2 and is connected to the outer side of the front disc 1-2, the outer surface of the bearing seat B7-7 parallel to the front disc 1-2 is connected to a motor B7-9, the rotating shaft of the motor B7-9 is connected to the shaft 7-5, the outer ring of the rotary support shaft B7-1 is connected to the treatment bed 8, and at the position where the rotary support shaft B7-1 is connected to the front disc 1-2, a circular hole is opened on the front disc, the center of the circle coincides with the axis line 1000 of the rotary support shaft B7-1, and the radius is equal to the inner diameter of the rotary support shaft B7-1, so that the bed board 8-1 of the treatment bed 8 can pass through.

Claims

1. A multi-angle non-isocentric irradiation bidirectional scanning particle therapy system, characterized in that: include: A rotating frame (1), in an initial state, two rectangular clamping plates (1-1) thereof refer to a rectangular coordinate system composed of an X-axis, a Y-axis and a Z-axis and can rotate with the rotating frame (1) with the Y-axis as the axis, the upper and lower end faces are parallel to the XY plane, the front and rear end faces are parallel to the XZ plane, and the whole is mirror-symmetrical with respect to the XY plane and the YZ plane respectively, the front end face is connected to a front disk (1-2) with a trapezoidal convex roller, the rear end face is connected to a rear disk (1-3) with a flat roller, the center of the front disk (1-2) and the rear disk (1-3) coincide with the Y-axis, and two arc-shaped support plates (1-4) are respectively connected to the outer side surfaces of the two rectangular clamping plates (1-1). The front disc (1-2) and the rear disc (1-3) are connected to the inner side surfaces, the front disc (1-2) falls on two supports A (1-5) with trapezoidal concave rollers, and the rear disc (1-3) falls on two supports B (1-6) with flat rollers, one of the supports B (1-6) is connected to a rotation drive mechanism (1-7), the bottom surfaces of the two supports A (1-5) and the two supports B (1-6) are connected to a base (1-8), the inner side surfaces of the two rectangular clamping plates (1-1) are connected to a counterweight (1-9) located below the XY plane; the inner sides of the two rectangular clamping plates (1-1) are connected to related components via a bracket (10); Two deflection magnets A (2) are connected to the inner side surfaces of the two rectangular clamping plates (1-1) via two groups of two brackets A (1-10-1) each, and are located close to the rear disk (1-3). The magnetic pole surfaces of the two magnetic poles A (2-1) of each deflection magnet A (2) are mirror-symmetrical with respect to the YZ plane. The two deflection magnets A (2) have the same shape, the same structure, the same deflection angle, and opposite deflection directions, so that the particle beam E (500) emitted from the second deflection magnet A (2) is parallel to the particle beam A (100) incident on the first deflection magnet A (2) along the Y axis toward the coordinate origin (0) of the rectangular coordinate system, is located above the XY plane, coincides with the YZ plane, and points to the XZ plane; A range shifter (3) connected to the inner side surfaces of the two rectangular clamping plates (1-1) via a set of two brackets B (1-10-2), located between the second deflection magnet A (2) and the coordinate origin (0), for adjusting the energy of the particle beam E (500); A rotating mechanism A (4), connected to the inner side surfaces of the two rectangular clamping plates (1-1) via a set of two rectangular plate brackets C (1-10-3), with its length in the Y-axis direction crossing the XZ plane, and its rotation axis coinciding with the axis of the particle beam E (500); A deflection magnet B (5) is connected to the rotating mechanism A (4) from the direction where the rear disk (1-3) is located, and the magnetic pole faces of its two magnetic poles B (5-1) are mirror-symmetrical with respect to the YZ plane; A 90° deflection magnet C (6) is connected to the rotating mechanism A (4) from the direction where the front disk (1-2) is located, and the magnetic pole faces of its two magnetic poles C (6-1) are mirror-symmetrical with respect to the YZ plane; A rotating mechanism B (7) connected to the outer side of the front disc (1-2), with its rotation axis (1000) parallel to the Y axis, within the YZ plane, and below the XY plane; A treatment bed (8) connected to the rotating mechanism B (7); A CBCT image positioning system (9) is connected to the inner side of the front disk (1-2), and the axis lines of the two positioning diamond beams (9-1) are in the XZ plane and perpendicularly intersect the axis line (1000) of the rotating mechanism B (7); The multi-angle irradiation and bidirectional scanning of the three-rotation axis particle therapy system are jointly completed by a treatment bed (8), a rotating frame (1), a rotating mechanism B (7), a CBCT image positioning system (9), two deflection magnets A (2), a deflection magnet B (5), a 90° deflection magnet C (6), a rotating mechanism A (4) and a range shifter (3); The patient is positioned on the treatment couch (8); The rotating frame (1) rotates to determine the irradiation angle; The rotating mechanism B (7) rotates in the opposite direction at equal angles relative to the rotating frame (1), so that the bed board (8-1) of the treatment bed (8) always remains horizontal; The CBCT image positioning system (9) is responsible for determining the collimation parameters; The treatment bed (8) is responsible for delivering the tumor target to the treatment center (2000) located at the intersection of the rotation axis (1000) of the rotating mechanism B (7) and the XZ plane; Two deflection magnets A (2) are responsible for radially translating the particle beams A (100) incident along the Y axis with different energies to a specified distance in the YZ plane, and transforming them into particle beams E (500) pointing to the XZ plane; The deflection magnet B (5) and the 90° deflection magnet C (6) are responsible for scanning in the Y-axis direction and make the particle beam I (900) emitted from the 90° deflection magnet C (6) parallel to each other, perpendicular to and intersecting the Y-axis, and covering the coordinate origin (0); The rotating mechanism A (4) is responsible for scanning in the X-axis direction, so that the particle beam I (900) emitted from the 90° deflection magnet C (6) is deflected with the axis of the rotating mechanism A (4) as the axis, and scans the coordinate origin (0) and the treatment center (2000). The reverse extension line of the axis of the particle beam I (900) is perpendicular to the rotation axis of the rotating mechanism A (4); The range shifter (3) changes the range of the particle beam I (900) in the patient's body by changing the energy of the particle beam E (500), so that bidirectional scanning can be performed at different depths of the tumor target area.

2. The rotating mechanism A (4) as described in claim 1 comprises two swivel support shafts A (4-1) whose axis lines coincide with the axis line of the particle beam E (500), the inner rings of the two swivel support shafts A (4-1) are respectively connected to the inner side surfaces facing each other of the two rectangular plate brackets C (1-10-3), the outer rings of the two swivel support shafts A (4-1) are respectively connected to a rectangular plate (4-2), the two rectangular plates (4-2) are connected to a rectangular frame (4-3), a 90° deflection magnet C (6) is installed in the rectangular frame (4-3), and is located on one side of the rear disk (1-3) relative to the XZ plane, and the surface of the rectangular plate (4-2) facing the rear disk (1-3) is connected to the deflection magnet B (5). Then, relative to the XZ plane, a section of turbine (4-4) is machined on the outer ring of the rotary support shaft A (4-1) located on one side of the rear disc (1-3) toward the XY plane, a worm (4-5) whose axis is parallel to the X-axis is movably connected to the turbine (4-4), the worm (4-5) passes through two rectangular clamps (1-1) and is connected to two bearings A (4-6), each bearing A (4-6) is embedded in a bearing seat A (4-7), the two bearing seats A (4-7) are respectively connected to the outer side surfaces of the two rectangular clamps (1-1), the outer side surface of a bearing seat A (4-7) is connected to a motor A (4-8), and the rotating shaft of the motor A (4-8) is connected to the worm (4-5).

3. The rotating mechanism B (7) as described in claim 1 comprises a swivel support shaft B (7-1), whose inner ring is connected to the outer side surface of the front disc (1-2), whose rotation axis (1000) is parallel to the Y axis, within the YZ plane, and below the XY plane. The outer edge of the outer ring of the swivel support shaft B (7-1) is processed into a pulley structure, which is movably connected to the belt (7-2). The belt (7-2) passes through two limiting rollers (7-3) and is movably connected to a small pulley (7-4). The small pulley (7-4) is connected to a shaft (7-5). The shaft (7-5) is movably connected to a group of bearings B (7-6). The group of bearings B (7-6) is embedded in a bearing seat B (7-7). The bearing seat B (7-7) is connected to a U-shaped seat (7-8), the U-shaped seat (7-8) is connected to the outer side of the front disc (1-2) across the belt (7-2), the bearing seat B (7-7) is connected to a motor B (7-9) at an outer surface parallel to the front disc (1-2), the rotating shaft of the motor B (7-9) is connected to the shaft (7-5), the outer ring of the swivel support shaft B (7-1) is connected to the treatment bed (8), and at the position where the swivel support shaft B (7-1) is connected to the front disc (1-2), a circular hole is opened on the front disc, the center of the circle coincides with the axis line (1000) of the swivel support shaft B (7-1), and the radius is equal to the inner diameter of the swivel support shaft B (7-1), so that the bed plate (8-1) of the treatment bed (8) can pass through.

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