A cell solution mixing structure

Abstract

This invention discloses a cell solution mixing structure, including a feeding chamber and a test tube. The feeding chamber includes a sample needle through-hole, a sample needle, and a mounting hole. The sample needle through-hole is vertically positioned within the feeding chamber, and the sample needle is inserted through it. The top of the sample needle is fixed within the sample needle through-hole by a sealing connector. The mounting hole is horizontally positioned within the feeding chamber and communicates with the sample needle through-hole. The cell solution mixing structure also includes a vibration structure disposed within the mounting hole, with its vibrating end abutting against the sample needle. The vibrating end of the vibration structure strikes the top of the sample needle, and the bottom of the sample needle amplifies the vibration to mix the cell solution in the test tube. This invention provides more efficient mixing of cell solutions in test tubes, solving the problems of cell adhesion to the walls, low cell viability, and uneven cell distribution in the solution caused by using a motor to mix the cell solution in the test tube.

Description

Technical Field

[0001] This invention relates to the field of cell analyzer technology, and more specifically to a cell solution mixing structure. Background Technology

[0002] A cell analyzer is a device for automated analysis and sorting of cells. It typically includes a cell solution mixing structure to homogenize the cell solution. This mixing structure usually comprises at least a feed chamber, a test tube, and a motor-driven rotating mixing mechanism. The feed chamber contains an injection needle, the bottom of which is inserted into the test tube to draw or add cell solution. The test tube is positioned on the motor-driven rotating mixing mechanism, which mixes the cell solution inside the test tube after it has been added.

[0003] In the prior art, when the motor-driven rotating mixing structure mixes the cell solution in the test tube, problems such as cell adhesion to the wall, low cell viability, and uneven cell distribution in the solution are prone to occur. Furthermore, since the rotating shaft of the motor-driven mixing structure needs to rotate, the sealing of the motor shaft is also required.

[0004] Therefore, a new technological solution is needed. Summary of the Invention

[0005] In view of this, embodiments of the present invention provide a cell solution mixing structure to at least address the shortcomings of existing cell solution mixing structures that use motor-driven rotation mixing structures.

[0006] The embodiments of the present invention provide the following technical solutions:

[0007] This invention provides a cell solution mixing structure, including a feeding chamber and a test tube. The feeding chamber includes a sample injection needle through-hole, a sample injection needle, and a mounting hole. The sample injection needle through-hole is vertically disposed on the feeding chamber. The sample injection needle is inserted through the sample injection needle through-hole. The top of the sample injection needle is limited and fixed in the sample injection needle through-hole by a sealing joint. The bottom of the sample injection needle extends out of the sample injection needle through-hole and is inserted into the test tube. The mounting hole is horizontally disposed on the feeding chamber and communicates with the sample injection needle through-hole.

[0008] The cell solution mixing structure also includes:

[0009] A vibration structure is disposed within the mounting hole, and the vibration end of the vibration structure abuts against the injection needle.

[0010] When the vibration structure is activated, the vibrating end of the vibration structure strikes the tip of the injection needle, and the bottom end of the injection needle amplifies the vibration to mix the cell solution in the test tube.

[0011] Furthermore, the vibration structure includes:

[0012] A base is disposed at the end of the mounting hole away from the injection needle through-hole;

[0013] A stacked piezoelectric ceramic is disposed in the mounting hole and located between the base and the injection needle through hole. The end of the stacked piezoelectric ceramic away from the injection needle through hole is limited by the base. The stacked piezoelectric ceramic can undergo mechanical deformation and recovery in the direction of the injection needle through hole through the inverse piezoelectric effect.

[0014] A vibrating top block is slidably inserted into the mounting hole and located between the stacked piezoelectric ceramic and the injection needle through hole. The vibrating top block is used to move within the mounting hole under the mechanical deformation of the stacked piezoelectric ceramic to drive the injection needle to vibrate.

[0015] A spring, the two ends of which are respectively connected to the vibrating top block and the base, the spring being used to pull the vibrating top block to always be in contact with the stacked piezoelectric ceramic.

[0016] Furthermore, the vibration structure also includes:

[0017] An adjusting screw, threaded on the base and abutting against the end of the stacked piezoelectric ceramic away from the vibrating top block, is used to adjust the position of the stacked piezoelectric ceramic and the vibrating top block.

[0018] Furthermore, the vibrating top block includes:

[0019] A top block groove is formed at one end of the vibrating top block near the stacked piezoelectric ceramic, for mounting the stacked piezoelectric ceramic at the end near the vibrating top block;

[0020] The stacked piezoelectric ceramics include:

[0021] A limiting part is provided on the outer wall of the stacked piezoelectric ceramic and located at the end of the stacked piezoelectric ceramic away from the vibrating top block;

[0022] When the end face of the stacked piezoelectric ceramic near the vibrating top block abuts against the bottom of the groove of the top block, the limiting part abuts against the edge of the groove of the top block or has a preset distance. The limiting part is used to prevent the vibrating top block from pressing the stacked piezoelectric ceramic too much under the action of the spring.

[0023] Furthermore, the mounting hole includes:

[0024] The first sub-mounting hole is formed on the feed chamber and communicates with the injection needle through hole;

[0025] The second sub-mounting hole is formed on the feed chamber and communicates with the first sub-mounting hole, and the inner diameter of the second sub-mounting hole is larger than the inner diameter of the first sub-mounting hole.

[0026] Furthermore, the vibrating top block includes:

[0027] A vibrating rod portion, which is sealed and slidably disposed within the first sub-mounting hole and is configured in correspondence with the injection nozzle;

[0028] The vibration base is connected to the vibration rod and is disposed in the second sub-mounting hole, and the top block groove is provided on the side of the vibration base away from the vibration rod.

[0029] Furthermore, the vibrating top block also includes:

[0030] A sealing ring is fitted onto the vibrating rod portion to seal the space between the vibrating rod portion and the first sub-mounting hole.

[0031] Furthermore, the vibrating top block is provided with a first connecting post, the base is provided with a second connecting post, and the two ends of the spring are respectively connected to the first connecting post and the second connecting post.

[0032] Furthermore, the injection needle is a metal injection needle.

[0033] Furthermore, the cell solution mixing structure further includes:

[0034] A test tube holder base, wherein a test tube holder is provided on the test tube holder base, and the test tube holder and the test tube holder base are completely sealed.

[0035] Furthermore, the test tube holder includes:

[0036] The connecting part is fully sealed to the test tube holder base at its bottom end, and the connecting part is covered with a sealing ring.

[0037] Compared with the prior art, the beneficial effects that the at least one technical solution adopted in the embodiments of the present invention can achieve include at least:

[0038] The present invention provides a cell solution mixing structure that uses a vibration structure to vibrate the injection needle, thereby amplifying the vibration at the bottom of the injection needle to mix the cell solution in the test tube. This solves the problems of cell adhesion to the wall, low cell viability, and uneven cell distribution in the solution caused by the use of a motor to rotate and mix the cell solution in the test tube in the prior art.

[0039] Furthermore, since no motor rotation structure is required, the test tube holder base and the test tube holder in the cell solution mixing structure of this application can be completely sealed to ensure the airtightness of the cell solution mixing structure. Attached Figure Description

[0040] To more clearly illustrate the technical solutions of the embodiments of this application, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0041] Figure 1 This is a cross-sectional view of the feed chamber portion in a cell solution mixing structure according to an embodiment of the present invention;

[0042] Figure 2 This is a cross-sectional view of the vibration structure according to an embodiment of the present invention;

[0043] Figure 3 This is a schematic diagram of the test tube holder base, test tube holder, and test tube according to an embodiment of the present invention.

[0044] 10. Feed chamber; 11. Injection needle through hole; 12. Injection needle; 13. Mounting hole; 131. First sub-mounting hole; 132. Second sub-mounting hole;

[0045] 20. Test tube;

[0046] 30. Vibration structure; 31. Base; 32. Stacked piezoelectric ceramics; 321. Limiting part; 33. Vibration top block; 331. Top block groove; 332. Vibration rod; 333. Vibration base; 334. Sealing ring; 34. Spring; 35. Adjusting screw; 36. First connecting post; 37. Second connecting post;

[0047] 40. Test tube holder;

[0048] 50. Test tube holder base. Detailed Implementation

[0049] The embodiments of this application will now be described in detail with reference to the accompanying drawings.

[0050] The following specific examples illustrate the implementation of this application. Those skilled in the art can easily understand other advantages and effects of this application from the content disclosed in this specification. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. This application can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of this application. It should be noted that, in the absence of conflict, the following embodiments and features in the embodiments can be combined with each other. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0051] It should be noted that various aspects of embodiments within the scope of the appended claims are described below. It will be apparent that the aspects described herein can be embodied in a wide variety of forms, and any particular structure and / or function described herein is merely illustrative. Based on this application, those skilled in the art will understand that one aspect described herein can be implemented independently of any other aspect, and two or more of these aspects can be combined in various ways. For example, any number and aspects set forth herein can be used to implement the device and / or practice the method. Additionally, this device and / or method can be implemented using structures and / or functionalities other than one or more of the aspects set forth herein.

[0052] It should also be noted that the illustrations provided in the following embodiments are only schematic representations of the basic concept of this application. The drawings only show the components related to this application and are not drawn according to the actual number, shape and size of the components in the actual implementation. In the actual implementation, the form, quantity and proportion of each component can be arbitrarily changed, and the layout of the components may also be more complex.

[0053] Additionally, specific details are provided in the following description to facilitate a thorough understanding of the examples. However, those skilled in the art will understand that practice can be carried out without these specific details.

[0054] Existing cell solution mixing structures, when using motor-driven rotary mixing, suffer from problems such as uneven cell distribution in the solution, low cell survival rate, cell adhesion to the wall, poor sealing, low injection pressure, and slow injection speed.

[0055] Based on this, the embodiments of this specification propose a processing solution: such as Figures 1-2As shown, the cell solution mixing structure of this application, by setting the vibration structure 30 on the feed chamber 10 to vibrate the injection needle 12, amplifies the vibration at the bottom of the injection needle 12 and mixes the cell solution in the test tube 20, thus eliminating the need for a motor to rotate the mixing structure and for the test tube 20 to rotate. This solves the problems of uneven cell distribution in solution, low cell survival rate, cell adhesion to the wall, poor sealing, low injection pressure, and slow injection speed in the prior art.

[0056] The technical solutions provided by the various embodiments of this application are described below with reference to the accompanying drawings.

[0057] like Figures 1-3 As shown, a cell solution mixing structure of the present invention includes a feeding chamber 10 and a test tube 20. The feeding chamber 10 includes a sample needle through hole 11, a sample needle 12, and a mounting hole 13. The sample needle through hole 11 is vertically disposed on the feeding chamber 10. The sample needle 12 is inserted through the sample needle through hole 11. The top of the sample needle 12 is limited and fixed in the sample needle through hole 11 by a sealing joint. The bottom of the sample needle 12 extends out of the sample needle through hole 11 and is inserted into the test tube 20. The mounting hole 13 is horizontally disposed on the feeding chamber 10 and communicates with the sample needle through hole 11.

[0058] This application mainly improves the feeding chamber 10, test tube 20 and its base portion of the cell solution mixing structure, while other structural parts are similar or the same as those in the prior art.

[0059] The injection needle 12 is inserted into the test tube 20 and used to deliver or extract cell solution into the test tube 20.

[0060] The size of the injection needle through hole 11 is slightly larger than that of the injection needle 12, so that the injection needle 12 can enter without affecting the subsequent vibration of the injection needle 12.

[0061] The cell solution mixing structure also includes a vibration structure 30, which is disposed in the mounting hole 13 and the vibration end of the vibration structure 30 abuts against the injection needle 12. When the vibration structure 30 is turned on, the vibration end of the vibration structure 30 strikes the top of the injection needle 12, and the bottom of the injection needle 12 amplifies the vibration to mix the cell solution in the test tube 20.

[0062] The vibration structure 30 can be constructed using a vibration motor or other vibration structures 30.

[0063] In some of these embodiments, the vibration structure 30 includes a base 31, stacked piezoelectric ceramics 32, a vibration top block 33, and a spring 34. The base 31 is located at the end of the mounting hole 13 away from the injection needle through-hole 11, providing mounting support. The stacked piezoelectric ceramic 32 is disposed in the mounting hole 13, between the base 31 and the injection needle through-hole 11, and the end of the stacked piezoelectric ceramic 32 away from the injection needle through-hole 11 is limited by the base 31. The stacked piezoelectric ceramic 32 can undergo mechanical deformation and recovery in the direction of the injection needle through-hole 11 through the inverse piezoelectric effect. The vibrating top block 33 is slidably inserted into the mounting hole 13, between the stacked piezoelectric ceramic 32 and the injection needle through-hole 11. The vibrating top block 33 is used to move in the mounting hole 13 under the mechanical deformation of the stacked piezoelectric ceramic 32 to drive the injection needle 12 to vibrate. The two ends of the spring 34 are connected to the vibrating top block 33 and the base 31 respectively. The spring 34 is used to pull the vibrating top block 33 to always be in contact with the stacked piezoelectric ceramic 32.

[0064] The base 31 provides mounting support for the stacked piezoelectric ceramics 32, the vibrating top block 33, and the other end of the spring 34.

[0065] Among them, piezoelectric ceramics will undergo mechanical deformation when performing the inverse piezoelectric effect.

[0066] Among them, the stacked piezoelectric ceramic 32 is formed by stacking multiple piezoelectric ceramics to increase the degree of mechanical deformation.

[0067] Specifically, when an external current is applied to the stacked piezoelectric ceramic 32, the stacked piezoelectric ceramic 32 can deform outward. Since the end of the stacked piezoelectric ceramic 32 away from the injection needle through hole 11 is held against by the base 31, the stacked piezoelectric ceramic 32 will deform in the direction of the injection needle through hole 11 to push the vibrating top block 33 to move.

[0068] The vibrating top block 33 is pushed by the stacked piezoelectric ceramic 32, which can push the injection needle 12. After the stacked piezoelectric ceramic 32 is restored, the vibrating top block 33 will be reset under the action of the spring 34. Thus, after the stacked piezoelectric ceramic 32 is repeatedly deformed and restored, the vibrating top block 33 will repeatedly strike the injection needle 12 to make the injection needle 12 vibrate. Since the vibrating top block 33 makes the tip of the injection needle 12 vibrate, the vibration will be gradually amplified after it is transmitted to the bottom of the injection needle 12, so as to achieve vibration mixing / stirring mixing of the cell solution in the test tube 20.

[0069] The spring 34 is used to pull the vibrating block 33 when the stacked piezoelectric ceramic 32 is restored, so that the vibrating block 33 is always in contact with the stacked piezoelectric ceramic 32, so that the vibrating block 33 can be pushed to move when the stacked piezoelectric ceramic 32 deforms again.

[0070] Furthermore, the vibration structure 30 also includes an adjusting screw 35, which is threaded onto the base 31 and abuts against the end of the stacked piezoelectric ceramic 32 away from the vibration top block 33, for adjusting the position of the stacked piezoelectric ceramic 32 and the vibration top block 33.

[0071] The adjustment screw 35 can reduce the space inside the mounting hole 13 and push the stacked piezoelectric ceramic 32 to move towards the side of the injection needle through hole 11. In turn, the stacked piezoelectric ceramic 32 pushes the vibrating top block 33 to move closer to the injection needle 12. The adjustment screw 35 can increase the space inside the mounting hole 13. At this time, the vibrating top block 33 and the stacked piezoelectric ceramic 32 move away from the injection needle 12 under the action of the spring 34.

[0072] The vibrating top block 33 includes a top block groove 331, which is formed at one end of the vibrating top block 33 near the stacked piezoelectric ceramic 32, for mounting the stacked piezoelectric ceramic 32 near the end of the vibrating top block 33.

[0073] The stacked piezoelectric ceramic 32 includes a limiting part 321, which is disposed on the outer wall of the stacked piezoelectric ceramic 32 and located at the end of the stacked piezoelectric ceramic 32 away from the vibrating top block 33. When the end face of the stacked piezoelectric ceramic 32 near the vibrating top block 33 abuts against the bottom of the groove of the top block groove 331, the limiting part 321 abuts against the edge of the groove of the top block groove 331 or has a preset interval. The limiting part 321 is used to prevent the vibrating top block 33 from pressing the stacked piezoelectric ceramic 32 too much under the action of the spring 34.

[0074] The limiting part 321 and the top block groove 331 cooperate to prevent the vibrating top block 33 from pressing the stacked piezoelectric ceramic 32 too much under the action of the spring 34, so that the stacked piezoelectric ceramic 32 can generate a piezoelectric effect.

[0075] Furthermore, the mounting hole 13 includes a first sub-mounting hole 131 and a second sub-mounting hole 132. The first sub-mounting hole 131 is formed on the feed chamber 10 and communicates with the injection needle through hole 11; the second sub-mounting hole 132 is formed on the feed chamber 10 and communicates with the first sub-mounting hole 131, and the inner diameter of the second sub-mounting hole 132 is larger than the inner diameter of the first sub-mounting hole 131.

[0076] The vibrating top block 33 includes a vibrating rod portion 332 and a vibrating base portion 333. The vibrating rod portion 332 is sealed and slidably disposed within the first sub-mounting hole 131 and is correspondingly disposed with respect to the injection needle 12. The vibrating base portion 333 is connected to the vibrating rod portion 332 and is disposed within the second sub-mounting hole 132. A top block groove 331 is formed on the side of the vibrating base portion 333 away from the vibrating rod portion 332.

[0077] The outer diameter of the vibrating rod 332 is smaller than the outer diameter of the vibrating base 333, which facilitates the matching of the size of the injection needle 12 and reduces the size and weight of the vibrating top block 33, making it easier for the vibrating top block 33 to vibrate.

[0078] Furthermore, the vibrating top block 33 also includes a sealing ring 334, which is fitted onto the vibrating rod portion 332 to seal between the vibrating rod portion 332 and the first sub-mounting hole 131.

[0079] The sealing ring 334 is used to seal the injection needle through hole 11 to ensure the injection pressure.

[0080] Specifically, when the vibrating rod 332 enters the injection needle through hole 11 to vibrate the injection needle 12, the sealing ring 334 is squeezed and deformed, which can provide good sealing performance, thereby increasing the injection pressure and injection speed.

[0081] In some embodiments, the vibrating top block 33 further includes a vibrating cylinder portion disposed on the side of the vibrating base 333 away from the vibrating rod portion 332. The vibrating cylinder portion abuts against the base 31 under the action of the spring 34, and the inner diameter of the vibrating cylinder portion is larger than the inner diameter of the vibrating groove. The vibrating cylinder portion is used to place the stacked piezoelectric ceramics 32 and the limiting portion 321.

[0082] The stacked piezoelectric ceramic 32 and the limiting part 321 can slide inside the vibrating cylinder.

[0083] Furthermore, the vibrating top block 33 is provided with a first connecting post 36, and the base 31 is provided with a second connecting post 37. The two ends of the spring 34 are respectively connected to the first connecting post 36 and the second connecting post 37.

[0084] The first connecting column 36 can be installed on the vibrating cylinder.

[0085] Specifically, a through hole is provided on the side wall of the vibrating cylinder, and the first connecting post 36 is disposed in the through hole. After the spring 34 is disposed in the through hole, it is connected to the first connecting post 36.

[0086] Furthermore, the injection needle 12 is a metal injection needle 12 to maintain the integrity of the function of the injection needle 12 when the injection needle 12 vibrates.

[0087] Furthermore, the cell solution mixing structure also includes a test tube holder base 50, on which a test tube holder 40 is provided. The test tube holder 40 and the test tube holder base 50 are completely sealed, thereby preventing leakage between the test tube holder base 50 and the test tube holder 40 and solving the problem that the motor shaft of the motor mixing structure cannot be sealed with the test tube holder base 50.

[0088] The test tube holder 40 includes a connecting part, the bottom end of which is fully sealed to the test tube holder base 50, and the connecting part is covered with a sealing ring 334, which can seal with the feed chamber 10.

[0089] The working principle of this invention is as follows:

[0090] When the cell solution in the test tube 20 is shaken and mixed, an electric current is applied to the stacked piezoelectric ceramic 32. Due to the existence of the inverse piezoelectric effect, the stacked piezoelectric ceramic 32 will undergo mechanical deformation, which will push the vibrating top block 33 to move towards the injection needle 12, thereby driving the injection needle 12 to vibrate.

[0091] After the stacked piezoelectric ceramic 32 is de-energized and restored, the vibrating top block 33 is reset by the action of the spring 34 and always remains in contact with the stacked piezoelectric ceramic 32 so that the stacked piezoelectric ceramic 32 continues to push the vibrating top block 33 to strike the injection needle 12 in the next cycle.

[0092] The vibration structure 30 of this invention is integrally mounted on the feed chamber 10. The vibration top block 33 of the vibration structure 30 touches the tip of the metal injection needle 12, causing the metal injection needle 12 to undergo elastic deformation and vibrate. This amplifies the vibration effect at the bottom of the injection needle 12, thereby mixing the liquid in the test tube 20. To ensure the mixing effect, different input voltages are applied to the piezoelectric ceramic according to the characteristics of different liquids (such as viscosity, concentration, etc.), and the piezoelectric ceramic will output different amplitude values.

[0093] Compared with the prior art, the test tube holder 40 and the test tube holder base 50 of this invention are fully sealed structures, eliminating the need to consider the sealing problem at the motor rotation shaft. The structure is simpler, maintenance is more convenient, and the overall sealing performance of the cell analyzer is improved.

[0094] The cell solution mixing structure of the present invention has the following advantages:

[0095] 1. The structure is simple and the operation is convenient, which improves the stability and maintainability of the equipment.

[0096] 2. High cell survival rate, reducing cell adhesion to the cell wall.

[0097] 3. High cell survival rate, reducing cell adhesion to the cell wall.

[0098] 4. Increase the injection pressure and increase the injection speed.

[0099] 5. High degree of modularity, lower cost.

[0100] 6. The control method is simple, the equipment is highly stable, and it has a wide range of applications and is easy to maintain.

[0101] In this specification, the same or similar parts between the various embodiments can be referred to mutually. Each embodiment focuses on describing the differences from other embodiments. In particular, for the product embodiments described later, since they correspond to the methods, the descriptions are relatively simple, and the relevant parts can be referred to the descriptions in the system embodiments.

[0102] The above description is merely a specific embodiment of this application, but the scope of protection of this application is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this application should be included within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.

Claims

1. A cell solution mixing structure, comprising a feed chamber and a test tube, characterized in that, The feeding chamber includes a sample needle through hole, a sample needle, and a mounting hole. The sample needle through hole is vertically disposed on the feeding chamber. The sample needle is inserted through the sample needle through hole. The top of the sample needle is limited and fixed in the sample needle through hole by a sealing joint. The bottom of the sample needle extends out of the sample needle through hole and is inserted into the test tube. The mounting hole is horizontally disposed on the feeding chamber and communicates with the sample needle through hole. The cell solution mixing structure also includes: A vibration structure is disposed within the mounting hole, and the vibration end of the vibration structure abuts against the injection needle. The vibration structure includes: A base is disposed at the end of the mounting hole away from the injection needle through-hole; A stacked piezoelectric ceramic is disposed in the mounting hole and located between the base and the injection needle through hole. The end of the stacked piezoelectric ceramic away from the injection needle through hole is limited by the base. The stacked piezoelectric ceramic can undergo mechanical deformation and recovery in the direction of the injection needle through hole through the inverse piezoelectric effect. A vibrating top block is slidably inserted into the mounting hole and located between the stacked piezoelectric ceramic and the injection needle through hole. The vibrating top block is used to move within the mounting hole under the mechanical deformation of the stacked piezoelectric ceramic to drive the injection needle to vibrate. A spring, the two ends of which are respectively connected to the vibrating top block and the base, the spring being used to pull the vibrating top block to always be in contact with the stacked piezoelectric ceramic; When the vibration structure is activated, the vibrating end of the vibration structure strikes the tip of the injection needle, and the bottom end of the injection needle amplifies the vibration to mix the cell solution in the test tube.

2. The cell solution mixing structure according to claim 1, characterized in that, The vibration structure also includes: An adjusting screw, threaded on the base and abutting against the end of the stacked piezoelectric ceramic away from the vibrating top block, is used to adjust the position of the stacked piezoelectric ceramic and the vibrating top block.

3. The cell solution mixing structure according to claim 2, characterized in that, The vibrating top block includes: A top block groove is formed at one end of the vibrating top block near the stacked piezoelectric ceramic, for mounting the stacked piezoelectric ceramic at the end near the vibrating top block; The stacked piezoelectric ceramics include: A limiting part is provided on the outer wall of the stacked piezoelectric ceramic and located at the end of the stacked piezoelectric ceramic away from the vibrating top block; When the end face of the stacked piezoelectric ceramic near the vibrating top block abuts against the bottom of the groove of the top block, the limiting part abuts against the edge of the groove of the top block or has a preset distance. The limiting part is used to prevent the vibrating top block from pressing the stacked piezoelectric ceramic too much under the action of the spring.

4. The cell solution mixing structure according to claim 3, characterized in that, The mounting holes include: The first sub-mounting hole is formed on the feed chamber and communicates with the injection needle through hole; The second sub-mounting hole is formed on the feed chamber and communicates with the first sub-mounting hole, and the inner diameter of the second sub-mounting hole is larger than the inner diameter of the first sub-mounting hole. The vibrating top block includes: A vibrating rod is sealed and slidably disposed within the first sub-mounting hole and is configured in correspondence with the injection nozzle; The vibration base is connected to the vibration rod and is disposed in the second sub-mounting hole, and the top block groove is provided on the side of the vibration base away from the vibration rod.

5. The cell solution mixing structure according to claim 4, characterized in that, The vibrating top block also includes: A sealing ring is fitted onto the vibrating rod portion to seal the space between the vibrating rod portion and the first sub-mounting hole.

6. The cell solution mixing structure according to claim 5, characterized in that, The vibrating top block is provided with a first connecting post, the base is provided with a second connecting post, and the two ends of the spring are respectively connected to the first connecting post and the second connecting post.

7. The cell solution mixing structure according to claim 1, characterized in that, The injection needle is a metal injection needle.

8. The cell solution mixing structure according to any one of claims 1 to 7, characterized in that, Also includes: A test tube holder base, wherein a test tube holder is provided on the test tube holder base, and the test tube holder and the test tube holder base are completely sealed.

9. The cell solution mixing structure according to claim 8, characterized in that, The test tube holder includes: The connecting part is fully sealed to the test tube holder base at its bottom end, and the connecting part is covered with a sealing ring.

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