Tissue closer

Abstract

The invention provides a tissue closer, and relates to the technical field of endoscopes. A tissue closer comprises a puncture cannula, a suture line, a pair of fixing pieces, a line pulling piece, a releasing piece and a driving guide wire. The puncture cannula is provided with a far end and a near end, the far end is a tip end, and the pair of fixing pieces, the wire pulling piece, the releasing piece and the driving guide wire are sequentially arranged from the far end to the near end; the release part is connected with the driving guide wire, and the driving guide wire can drive the release part to move in the axial direction of the puncture cannula; the releasing piece is provided with a threading hole, and the suture line penetrates through the threading hole; the thread pulling piece is provided with a thread tightening hole, the two ends of the suture thread penetrate through the thread tightening hole in the same direction, the hole wall of the thread tightening hole applies clamping force to the suture thread, and the clamping force is smaller than the breaking strength of the suture thread; one of the pair of fixing pieces is connected with one end of the suture line, and the other one of the pair of fixing pieces is connected with the other end of the suture line. The tissue closer provided by the invention can be suitable for tissue butt joint and large gastrointestinal tract defect closing under an endoscope.

Description

Technical Field

[0001] The present application relates to the technical field of endoscopes, and in particular to a tissue closure device. Background Art

[0002] With the development of clinical internal medicine, endoscopic treatments for the digestive tract or respiratory tract have become increasingly diverse and common, such as using biopsy forceps for tissue pathology analysis, using high-frequency incision knives to remove diseased tissue, etc. These operations usually cause artificial internal wounds.

[0003] At present, endoscopic hemostatic clips are mostly used to close the defect. However, due to the limitation of the opening size of the endoscopic hemostatic clips, endoscopic hemostatic clips are only effective for small-scale mucosal closure and small-sized defects, and cannot be adapted to endoscopic tissue docking and closure of large gastrointestinal defects. Summary of the invention

[0004] In view of this, the purpose of this application is to overcome the deficiencies in the prior art and to provide a tissue closure device with a wide range of adaptability, suitable for a variety of wounds, and capable of endoscopic tissue docking and closure of large gastrointestinal defects, as well as capable of staggered layer connections.

[0005] This application provides the following technical solutions:

[0006] The present application provides a tissue closure device, which includes a puncture cannula, a suture, a pair of fixing members, a wire puller, a release member, and a drive guide wire, wherein the pair of fixing members, the wire puller, the release member, and the drive guide wire are respectively movably arranged in the puncture cannula; wherein the puncture cannula has a distal end and a proximal end, the distal end is configured as a tip, and the pair of fixing members, the wire puller, the release member, and the drive guide wire are sequentially arranged from the distal end to the proximal end;

[0007] The release member is connected to the drive guide wire, and the drive guide wire can drive the release member to move along the axial direction of the puncture sleeve; wherein the release member has a threading hole, and the suture is passed through the threading hole;

[0008] The wire pulling member has a wire tightening hole, and the two ends of the suture are inserted into the wire tightening hole in the same direction. The hole wall of the wire tightening hole exerts a clamping force on the suture, and the clamping force is less than the breaking strength of the suture;

[0009] One of the pair of fixing members is connected to one end of the suture, and the other of the pair of fixing members is connected to the other end of the suture.

[0010] In some of these embodiments, the tip is provided with a cutting edge.

[0011] In some embodiments, the fixing member has a head end and a tail end, the head end is close to the distal end, and the tail end is far away from the distal end, the outer wall of the tail end of the fixing member is provided with a plurality of storage grooves, the plurality of storage grooves extend from the end surface of the tail end toward the head end, the tail end is connected to one end of the suture, and the connection between the suture and the tail end is located in the storage groove.

[0012] In some of the embodiments, a receiving groove is further provided in the middle of the end surface of the tail end, the receiving groove is extended from the end surface of the tail end toward the head end, and the storage groove and the receiving groove are connected to each other.

[0013] In some embodiments, a wire groove is provided on the side wall of the fixing member, and the wire groove extends from the end surface of the head end to the end surface of the tail end;

[0014] And / or, the end surface of the head end of the fixing member is provided with a wire passing hole, and the wire passing hole extends from the end surface of the head end to the bottom of the accommodating groove.

[0015] In some embodiments, the portion of the fixing member located between adjacent placement grooves is configured as an elastic structure, and the initial outer diameter of the portion of the fixing member located in the placement groove is greater than the inner diameter of the puncture sleeve.

[0016] In some embodiments, the outer wall of the tail end has a flange portion, and the initial outer diameter of the flange portion is larger than the inner diameter of the puncture sleeve.

[0017] In some embodiments, two ends of the suture thread are inserted into the same tightening hole;

[0018] Alternatively, the two ends of the suture thread are respectively inserted into different tightening holes, and the suture thread and the tightening hole are transitionally matched.

[0019] In some embodiments, the inner wall of the tightening hole is provided with barbs, and the barbs are biased toward an end of the tightening hole away from the fixing member.

[0020] In some embodiments, the outer wall of the pull wire member is provided with an elastic protrusion and a recessed portion, and the pull wire member entering and exiting the puncture sleeve can enable the elastic protrusion to switch between a compressed state located inside the recessed portion and an expanded state located outside the recessed portion; wherein, in the expanded state, the maximum outer diameter of the pull wire member is greater than the inner diameter of the puncture sleeve.

[0021] In some embodiments, a groove is provided on the outer wall of the wire pulling member, the groove is extended along the circumference of the wire pulling member, and the recessed portion is provided in the groove;

[0022] The raised portion includes a plurality of elastic strips, which are arranged at intervals along the circumference of the wire pulling member, one end of the elastic strip is connected to one side of the groove, the other end of the elastic strip is connected to the other side of the groove, and the middle part of the elastic strip is arched in the direction away from the wire pulling member.

[0023] In some of the embodiments, the threading hole is provided at one end of the release member, and the other end of the release member is connected to the drive guide wire; wherein, the hole wall of the threading hole is provided with a breakable area, and the breaking of the breakable area can cause the hole wall of the threading hole to form a non-closed structure.

[0024] In some embodiments, the breakable area is provided with a breaking groove, and the breaking groove extends from one end surface of the threading hole to the other end surface.

[0025] In some of the embodiments, an end surface of one end of the release member having the threading hole is provided with an open groove, and the threading hole passes through two groove walls of the open groove.

[0026] The embodiments of the present application have the following advantages:

[0027] The present application provides a tissue closure device, which is inserted into one side of a wound using a puncture cannula. By manipulating the driving guide wire to drive the release member to move distally, the first fixing member is pushed out of the puncture cannula, and the puncture cannula is pulled out to retain the first fixing member in the tissue at the edge of the wound, wherein, under the action of the surface tension of the tissue mucosa, the hole punctured by the puncture cannula is close to being closed, further enhancing the restraint force on the first fixing member so that it will not fall out of the tissue. The other side of the wound is inserted using a puncture cannula. By manipulating the driving guide wire to drive the release member to move distally, the second fixing member is pushed out of the puncture cannula, and the puncture cannula is pulled out to retain the second fixing member in the tissue at the edge of the wound, wherein, under the action of the surface tension of the tissue mucosa, the hole punctured by the puncture cannula is close to being closed, further enhancing the restraint force on the second fixing member so that it will not fall out of the tissue. By continuing to manipulate the driving guide wire to drive the release member to move distally, the pull wire member is pushed out of the puncture cannula, so that the pull wire member is separated from the puncture cannula and exposed. By controlling the guide wire to pull back the release member, the wire puller is pulled close to the distal end, but the wire puller cannot enter the puncture cannula due to the end blocking the puncture cannula. Then the suture in the tightening hole of the wire puller is stressed, so that the two fixing members are pulled together, and the wound is closed. Finally, the suture is cut and the puncture cannula is removed.

[0028] Obviously, such a design allows for more flexible treatment of gastrointestinal defects of different sizes and types, especially for those that are difficult to effectively treat with traditional hemostatic clips. In addition, the device also supports staggered connection, which means it can better adapt to the needs of repairing irregular shapes or multi-level tissue injuries.

[0029] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and understandable, preferred embodiments are given below and described in detail with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0031] Figure 1 A schematic structural diagram of a tissue closure device provided in the first embodiment of the present application is shown;

[0032] Figure 2 A structural schematic diagram showing a fixing member of a tissue closure device provided in the second embodiment of the present application from one perspective;

[0033] Figure 3 A schematic structural diagram showing another perspective of a fixing member of a tissue closure device provided in the second embodiment of the present application;

[0034] Figure 4 A structural schematic diagram showing a perspective of a fixing member of a tissue closure device provided in the first embodiment of the present application;

[0035] Figure 5 A schematic structural diagram showing another perspective of a fixing member of a tissue closure device provided in the first embodiment of the present application;

[0036] Figure 6 A structural schematic diagram showing a fixing member of a tissue closure device provided in a third embodiment of the present application from one perspective;

[0037] Figure 7 A schematic structural diagram showing another perspective of a fixing member of a tissue closure device provided in the third embodiment of the present application;

[0038] Figure 8 A structural schematic diagram showing a fixing member of a tissue closure device provided in a fourth embodiment of the present application from one perspective;

[0039] Fig. 9 A schematic structural diagram showing another perspective of a fixing member of a tissue closure device provided in the fourth embodiment of the present application;

[0040] Fig.10 A structural schematic diagram showing a wire puller of a tissue closure device provided in the first embodiment of the present application from one perspective;

[0041] Fig.11 A schematic structural diagram showing a wire puller of a tissue closure device provided in a second embodiment of the present application from one perspective;

[0042] Fig.12 A schematic structural diagram showing another perspective of a wire puller of a tissue closure device provided in the second embodiment of the present application;

[0043] Fig.13 A schematic structural diagram showing a release member of a tissue closure device provided in the first embodiment of the present application from one perspective;

[0044] Fig.14 A schematic structural diagram showing another perspective of a release member of a tissue closure provided in the first embodiment of the present application;

[0045] Fig.15 The operation schematic diagram of step 1 in the working principle of the present application is shown;

[0046] Fig.16 The operation schematic diagram of step 2 in the working principle of the present application is shown;

[0047] Fig.17 The schematic diagram of the operation of step 5 in the working principle of the present application is shown;

[0048] Fig.18 The operation schematic diagram of step 6 in the working principle of the present application is shown;

[0049] Fig.19 The operation diagram of step 7 in the working principle of the present application is shown.

[0050] Description of main component symbols:

[0051] 100-puncture sleeve; 110-distal end; 120-proximal end; 200-fixing piece; 210-wire groove; 220-head end; 230-tail end; 240-accommodating groove; 250-storage groove; 260-first wire fixing hole; 270-wire passing hole; 280-flange; 300-wire pulling piece; 310-tightening hole; 320-elastic strip; 330-groove; 400-releasing piece; 410-threading hole; 420-breaking groove; 430-opening groove; 440-second wire fixing hole; 500-driving guide wire; 600-suture. DETAILED DESCRIPTION

[0052] The embodiments of the present application are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present application, and cannot be understood as limiting the present application.

[0053] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. In contrast, when an element is referred to as being "directly on" another element, there is no intermediate element. The terms "vertical", "horizontal", "left", "right" and similar expressions used herein are for illustrative purposes only.

[0054] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0055] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0056] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of the template are only for the purpose of describing specific embodiments and are not intended to limit this application. The term "and / or" used herein includes any and all combinations of one or more of the related listed items.

[0057] In the related technologies, with the development of clinical internal medicine, endoscopic treatments for the digestive tract or respiratory tract have become increasingly abundant and common, such as using biopsy forceps for tissue pathology analysis, using high-frequency incision knives for diseased tissue removal, etc. These operations usually cause artificial internal wounds.

[0058] Endoscopic hemostatic clips are usually used to close the defect. However, due to the limitation of the opening size of the endoscopic hemostatic clips, endoscopic hemostatic clips are only effective for small-scale mucosal closure and small-sized defects, and cannot be used for endoscopic tissue docking and closure of large gastrointestinal defects.

[0059] like Figure 1 As shown, in order to solve the above technical problems, an embodiment of the present application provides a tissue closure device, which includes a puncture sleeve 100, a suture 600, a pair of fixing members 200, a wire pull member 300, a release member 400 and a drive guide wire 500, wherein the pair of fixing members 200, the wire pull member 300, the release member 400 and the drive guide wire 500 are respectively movably arranged in the puncture sleeve 100; wherein the puncture sleeve 100 has a distal end 110 and a proximal end 120, the distal end 110 is set as a pointed end, and the pair of fixing members 200, the wire pull member 300, the release member 400 and the drive guide wire 500 are sequentially arranged from the distal end 110 to the proximal end 120. The release member 400 is connected to the driving guide wire 500, and the driving guide wire 500 can drive the release member 400 to move axially along the puncture sleeve 100; wherein the release member 400 has a threading hole 410, and the suture 600 is passed through the threading hole 410; the wire pulling member 300 has a tightening hole 310, and both ends of the suture 600 are passed through the tightening hole 310 in the same direction, and the hole wall of the tightening hole 310 applies a clamping force to the suture 600, and the clamping force is less than the breaking strength of the suture 600; one of the pair of fixing members 200 is connected to one end of the suture 600, and the other of the pair of fixing members 200 is connected to the other end of the suture 600.

[0060] In these embodiments, the design purpose of the present application is to solve the problem of large-scale or complex wound closure encountered in endoscopic surgery. Among them, the puncture sleeve 100: as the basic structure of the entire device, it is a slender tubular object, one end of which is a tip (distal end 110) for easy puncture of tissues; the other end is a proximal end 120 for operator control.

[0061] Suture 600: This thread is used to close the tissue. The suture 600 passes through the threading hole 410 on the release member 400 , the middle of the suture 600 is inserted into the threading hole 410 , and both ends of the suture 600 are clamped by the wire pulling member 300 .

[0062] For example, the suture 600 may be a common suture 600, an absorbable suture 600, a unidirectional serrated suture 600, etc., without limitation.

[0063] Fixing members 200: There are two fixing members 200, and both ends of the suture 600 are connected with fixing members 200. These fixing members 200 can be pushed into and positioned in the edges of the tissues that need to be closed, and when the suture 600 is tightened, they can help fix and close the edges of the wound and promote healing.

[0064] The wire puller 300 has a tightening hole 310, and is used to clamp the suture 600 and give appropriate tension. Its design ensures that the suture 600 will not break easily even if a certain force is applied to it, and prevents the suture 600 from breaking or loosening after being fixed by the wire puller 300, so that the wire puller 300 can be used to keep the incision closed after the suture 600 is tightened.

[0065] Release member 400: The release member 400 is connected to the driving guide wire 500 and can move inside the puncture sleeve 100. The release member 400 has a threading hole 410 for the suture 600 to pass through. As the release member 400 moves axially along the puncture sleeve 100, it can adjust the position of the suture 600, the fixing member 200 and the pulling member 300, thereby helping to complete the tissue docking and closure process.

[0066] Drive guide wire 500: used to control the action of release member 400, so that the doctor can accurately control the entire closing process.

[0067] It should be noted that, for ease of understanding, Fig.15 , Fig.16 , Fig.17 , Fig.18 and Fig.19 As shown, the working principle of this application is as follows:

[0068] Step 1: Use the puncture cannula 100 to insert into one side of the wound.

[0069] Step 2: The release member 400 is driven to move toward the distal end 110 by manipulating the driving guide wire 500 to push the first fixing member 200 out of the puncture cannula 100, and the puncture cannula 100 is removed so that the first fixing member 200 is retained in the tissue at the edge of the wound, wherein, under the action of the surface tension of the tissue mucosa, the hole punctured by the puncture cannula 100 is forced to be close to closure, further enhancing the restraining force on the first fixing member 200 so that it will not fall out of the tissue.

[0070] Step 3: Use the puncture cannula 100 to insert into the other side of the wound.

[0071] Step 4: The release member 400 is driven to move toward the distal end 110 by manipulating the driving guide wire 500 to push the second fixing member 200 out of the puncture cannula 100, and the puncture cannula 100 is removed so that the second fixing member 200 is retained in the tissue at the edge of the wound, wherein, under the action of the surface tension of the tissue mucosa, the hole punctured by the puncture cannula 100 is forced to be nearly closed, further enhancing the restraining force on the second fixing member 200 so that it will not fall out of the tissue.

[0072] Step 5: Continue to manipulate the driving guide wire 500 to drive the release member 400 to move toward the distal end 110 to push the pull wire member 300 out of the puncture cannula 100 , so that the pull wire member 300 is separated from the puncture cannula 100 and exposed.

[0073] Step 6: By controlling the driving guide wire 500 to pull back the release member 400, the pull wire member 300 is pulled close to the distal end 110, but due to the obstruction of the end of the puncture cannula 100, the pull wire member 300 cannot enter the puncture cannula 100, and the suture 600 in the tightening hole 310 of the pull wire member 300 is stressed, so that the two fixing members 200 are pulled together.

[0074] Step 7: After the wound is closed, the endoscopic forceps can be used to cut the suture 600 and remove the puncture sleeve 100. The connection between the suture 600 and the release member 400 can also be directly disconnected by pulling off the distal end of the threading hole 410 of the release member 400.

[0075] Obviously, such a design allows for more flexible treatment of gastrointestinal defects of different sizes and types, especially for those that are difficult to effectively treat with traditional hemostatic clips. In addition, the device also supports staggered connection, which means it can better adapt to the needs of repairing irregular shapes or multi-level tissue injuries.

[0076] In addition, compared with the traditional surgical suture incisions that easily cause other external wounds and increase the patient's physical burden, the tissue closure provided by the present application will not cause external wounds during use, and the secondary trauma caused to the patient is small, which is beneficial to the patient's recovery. It should be noted that the closure, hemostasis and graft fixation of internal tissues are one of the areas with major unmet needs in clinical practice, and the suture 600 suture used in surgery has a very high flexibility and convenience. It is of great significance to introduce the suture 600 suture method into internal surgery. This technology seems to have great potential, especially in improving the efficiency of endoscopic surgery and improving patient recovery.

[0077] Furthermore, for the treatment of small-scale mucosal closure and small-sized defects, the use of endoscopic hemostatic clips for treatment has the following disadvantages: endoscopic hemostatic clips are mostly made of metal. Although it is generally believed that the above-mentioned implanted closures can fall off within a certain period of time, it has been clinically found that they cannot fall off or are wrapped by new tissues, and removing the clip body is a high-risk operation, which may cause the healed wound to collapse again. The metal implants remaining in the body have a great impact on the patient, such as: scratches during eating or exercise, and inability to perform MRI examinations. In addition, when the above-mentioned implanted closures remain in the body for a long time, it is not ruled out that they will cause allergic reactions to the surrounding mucosa. Obviously, the use of the tissue closure provided by the present application can avoid the above problems and has considerable technical advantages.

[0078] like Figure 1 As shown, in some embodiments, the tip is provided with a cutting edge.

[0079] In these embodiments, the distal end 110 of the puncture sleeve 100 is configured as a tip, and a cutting edge is provided at the tip, so that the distal end 110 has a puncture function, thereby being able to puncture the mucosa and create a cavity for the fixing member 200 to invade the mucosa and hook.

[0080] Exemplary, in the present embodiment, the blade is single-edged, i.e. bamboo cross-section type. Of course, in other embodiments, the blade can also be set to three blades, five blades, etc., as long as the puncture effect can be formed.

[0081] like Figure 2 and Figure 3 As shown, in some embodiments, the fixing member 200 has a head end 220 and a tail end 230, the head end 220 is close to the distal end 110, and the tail end 230 is far away from the distal end 110, and the outer wall of the tail end 230 of the fixing member 200 is provided with a plurality of storage grooves 250, and the plurality of storage grooves 250 extend from the end surface of the tail end 230 toward the head end 220, the tail end 230 is connected to one end of the suture 600, and the connection between the suture 600 and the tail end 230 is located in the storage groove 250.

[0082] In these embodiments, the design of the fixing member 200 is further refined. By providing a plurality of placement grooves 250 on the outer wall of the tail end 230 of the fixing member 200, one end of the suture 600 can be placed in these placement grooves 250. This not only plays a certain protective role, but also prevents the suture 600 from being directly exposed to the outside environment or other tissues, and reduces the risk of wear caused by friction and other reasons; moreover, after the fixing member 200 enters the mucosa, when the suture 600 is pulled back, the suture 600 can be separated from the placement groove 250, and then the middle part of the fixing member 200 is dragged to adjust the posture of the fixing member 200, so that it is close to horizontal or horizontal in the mucosa, thereby preventing the problem of the fixing member 200 being separated from the mucosa due to the pulling back of the suture 600.

[0083] Furthermore, by providing the storage groove 250 , the volume of the fixing member 200 can be reduced, thereby reducing the impact on the human body.

[0084] Exemplarily, the edge of the head end 220 is chamfered, and the edge of the tail end 230 is chamfered, thereby preventing the fixing member 200 from stabbing the tissue for the second time.

[0085] Obviously, since the end of the tail end 230 is an integrated structure, the overall rigidity and strength of the fixing member 200 can be ensured, which is not conducive to the fixing member 200 being separated from the mucosa.

[0086] like Figure 4 and Figure 5 As shown, in some embodiments, a receiving groove 240 is further provided in the middle of the end surface of the tail end 230 , and the receiving groove 240 extends from the end surface of the tail end 230 toward the head end 220 , and the storage groove 250 and the receiving groove 240 are connected.

[0087] In these embodiments, by placing one end of the suture 600 in the receiving groove 240, it is possible to ensure that the suture 600 is more accurately placed inside the fixing member 200, ensure that the surface of the fixing member 200 is smooth, and help reduce the pushing resistance and reduce the wear of the suture 600. At the same time, this also helps to maintain the stability of the suture 600 during the operation.

[0088] When the suture 600 is placed in the receiving groove 240, it can be supported in multiple directions, not only from the lateral support provided by the storage groove 250, but also from the support at the bottom of the receiving groove 240. This can reduce the stress concentration points of the suture 600 caused by pulling, thereby enhancing the tensile strength of the entire system.

[0089] Furthermore, since the receiving groove 240 and the placement groove 250 are connected, when the fixing member 200 enters the mucosa, it is usually non-directional. The multiple placement grooves 250 can make the suture 600 detach from the placement grooves 250 in all directions, so that the fixing member 200 is placed horizontally under the pulling force of the suture 600, thereby avoiding pulling back the suture 600 and driving the fixing member 200 away from the mucosa.

[0090] Furthermore, the fixing member 200 can be further lightened by providing the receiving groove 240 .

[0091] Exemplarily, the suture 600 is connected to the bottom of the receiving groove 240. Optionally, the bottom of the receiving groove 240 is provided with a first thread fixing hole 260, and the end of the suture 600 is passed through the first thread fixing hole 260 and is fixed by applying glue.

[0092] Exemplarily, the slot width of the storage slot 250 is greater than the diameter of the suture 600 , so that the suture 600 can enter and exit the storage slot 250 easily and reduce the wear of the slot 250 on the suture 600 .

[0093] like Figure 4 and Figure 5 As shown, in some embodiments, a wire groove 210 is disposed on the side wall of the fixing member 200 , and the wire groove 210 extends from the end surface of the head end 220 to the end surface of the tail end 230 .

[0094] In these embodiments, the wire groove 210 is used to provide a holding space for the suture 600 connected to the fixing member 200 near the tip when passing through the fixing member 200 away from the tip, so as to prevent the suture 600 from being clamped between the puncture sleeve 100 and the fixing member 200.

[0095] Of course, when the gap between the fixing member 200 and the puncture sleeve 100 is larger than the wire diameter of the suture thread 600, the wire groove 210 may not be provided.

[0096] like Figure 6 and Figure 7 As shown, in some embodiments, the end surface of the head end 220 of the fixing member 200 is provided with a wire hole 270 , and the wire hole 270 extends from the end surface of the head end 220 to the bottom of the accommodating groove 240 .

[0097] In these embodiments, the function of setting the wire hole 270 is the same as that of setting the wire groove 210. The wire hole 270 is used to provide a holding space for the suture 600 connected to the fixing member 200 close to the tip when passing through the fixing member 200 away from the tip, thereby preventing the suture 600 from being clamped between the puncture sleeve 100 and the fixing member 200.

[0098] like Figure 8 and Fig. 9 As shown, in some embodiments, the portion of the fixing member 200 located between adjacent placement grooves 250 is configured as an elastic structure, and the initial outer diameter of the portion of the fixing member 200 located in the placement groove 250 is greater than the inner diameter of the puncture sleeve 100 .

[0099] In these embodiments, when the fixing member 200 is in the puncture cannula 100, the natural outer diameter (i.e., the initial outer diameter) of the fixing member 200 is slightly larger than the inner diameter of the puncture cannula 100, but the outer diameter of the fixing member 200 gradually increases from the head end 220 to the tail end 230 by utilizing the elasticity of the side wall of the tail end 230 of the fixing member 200, so that the fixing member 200 can still move in the puncture cannula 100. When the fixing member 200 is released from the puncture cannula 100, it can expand circumferentially again, so that the anti-slip force between the tissues at the incision becomes larger, that is, it is more difficult for the fixing member 200 to slip out of the tissue.

[0100] For example, the side wall of the tail end 230 of the fixing member 200 is set to a thin-walled structure. This design makes the side wall of the tail end 230 have greater elasticity. The reasons for the above elasticity are: first, the elastic deformation is easy to recover; second, the thin-walled structure makes it easier to deform circumferentially (especially the end face of the tail end 230); third, when there is no external force, the above outer wall will usually automatically expand circumferentially, which is usually caused by residual stress during processing.

[0101] like Figure 8 and Fig. 9 As shown, in some embodiments, the outer wall of the tail end 230 has a flange portion 280, and the initial outer diameter of the flange portion 280 is larger than the inner diameter of the puncture sleeve.

[0102] In these embodiments, when the fixing member 200 is pushed through the puncture sleeve 100 and reaches the target position, the flange portion 280 cannot easily re-enter the puncture sleeve 100 due to its larger diameter. This effectively prevents the fixing member 200 from accidentally retreating or shifting, ensuring the safety and stability of the closing operation.

[0103] Since the outer diameter of the flange portion 280 is greater than the inner diameter of the puncture sleeve 100, it will expand after passing through the sleeve, thereby increasing the area in contact with the surrounding tissue. Such a structure can be better anchored in the tissue and provide a stronger fixing force, which is more effective when treating larger or irregularly shaped defects.

[0104] Furthermore, by providing the flange 280 , the tail end 230 of the fixing member 200 contacts the inner wall of the puncture sleeve 100 through the flange 280 , thereby reducing the contact surface between the fixing member 200 and the puncture sleeve, thereby reducing the pushing resistance. It should be noted that the flange 280 is also cut off by the storage groove 250 .

[0105] like Fig.10 As shown, in some embodiments, both ends of the suture thread 600 are passed through the same tightening hole 310 .

[0106] In these embodiments, the wire pulling hole is provided with a tightening hole 310, and the two ends of the suture 600 are limited by passing through the tightening hole 310 in a direction from the end of the wire feeding hole away from the fastener to the end of the fastener close to the fastener, and the same tightening hole 310 is used to limit the two ends of the suture 600.

[0107] For example, the diameter of the suture 600 is slightly larger than the minimum diameter of the tightening hole 310 , thereby enabling the tightening hole 310 to exert a clamping force on the suture 600 .

[0108] In some embodiments, two ends of the suture thread 600 are respectively inserted into different tightening holes 310 , and the suture thread 600 and the tightening hole 310 are transitionally matched.

[0109] In these embodiments, the wire pulling member 300 has two tightening holes 310, and the two ends of the suture 600 are respectively inserted into the corresponding tightening holes 310, and the suture 600 and the tightening holes 310 are provided with an interference fit. The transition fit between the suture 600 and the tightening holes 310 means that the friction between the two is large enough to prevent the suture 600 from slipping out easily, but not so large that it is difficult to adjust.

[0110] In some embodiments, the inner wall of the tightening hole 310 is provided with barbs, and the barbs are inclined toward an end of the tightening hole 310 away from the fixing member 200 .

[0111] In these embodiments, the barb design can effectively prevent the suture 600 from retreating after being tightened. Once the suture 600 is pulled through the barb, the barb will hook the suture 600, so that it cannot easily move in the opposite direction, that is, the tightening hole 310 has a one-way passability. This ensures that the tension during the closing process remains stable, improving the safety and reliability of the closing.

[0112] Among them, the barbs increase the friction between the inner wall of the tightening hole 310 and the suture 600, so that the suture 600 is more firmly fixed in the tightening hole 310. This is very important for maintaining the closure effect, especially when the tension needs to be maintained for a long time.

[0113] Obviously, by providing a reliable anti-slip mechanism, there is no need to frequently check or readjust the position of the suture 600, so that more focus can be placed on other critical operating steps, improving overall surgical efficiency. In addition, if the closing tension needs to be fine-tuned during surgery, the barbed structure allows the doctor to pull the suture 600 multiple times to achieve the ideal tension state without causing the previous tension to be lost with each adjustment. Furthermore, when dealing with complex multi-layer wounds or situations requiring high-tension closure, the barbs can provide additional support to ensure that the closure point will not loosen due to the patient's activities or other factors even during postoperative recovery.

[0114] In summary, the design that the inner wall of the tightening hole 310 is provided with barbs and the barbs are biased toward the end of the tightening hole 310 away from the fixing member 200 is intended to enhance the fixing ability of the suture 600 by physical means to prevent it from accidentally loosening, while providing a convenient one-way adjustment function. Such a design has significant advantages in improving the overall performance of the tissue closure device, especially in ensuring the durability and safety of the closing effect.

[0115] like Fig.11 and Fig.12As shown, in some embodiments, the outer wall of the pull wire member 300 is provided with an elastic protrusion and a recessed portion, and the pull wire member 300 enters and exits the puncture sleeve 100 so that the elastic protrusion can switch between a compressed state located inside the recessed portion and an expanded state located outside the recessed portion; wherein, in the expanded state, the maximum outer diameter of the pull wire member 300 is greater than the inner diameter of the puncture sleeve 100.

[0116] In these embodiments, in the compressed state, when the wire puller 300 is pushed into or pulled out of the puncture cannula 100, the elastic protrusion is compressed into the recessed portion. At this time, the overall outer diameter of the wire puller 300 is reduced, so that it can smoothly pass through the puncture cannula 100. In this state, the wire puller 300 has a smaller outer diameter and can easily move inside the puncture cannula 100.

[0117] Expanded state: Once the pull wire member 300 completely enters the target position and extends from the distal end 110 of the puncture cannula 100, the elastic protrusion will naturally return to its original shape, that is, the expanded state. In the expanded state, the maximum outer diameter of the pull wire member 300 is larger than the inner diameter of the puncture cannula 100, which can prevent the pull wire member 300 from accidentally retreating into the puncture cannula 100. The expanded state provides additional fixing force to ensure that the pull wire member 300 is firmly located outside the puncture cannula 100.

[0118] In other words, after the wire puller 300 is pushed out of the puncture sleeve 100, the suture 600 is gathered. Usually, the wire puller 300 is not easy to be pulled into the puncture sleeve 100 again. However, once pulled into the puncture sleeve 100, it needs to be pushed out again. The wire puller 300 needs to be fixed and the suture 600 needs to be moved, so as to gather. In order to avoid the above risks, the above improvements are proposed.

[0119] The selection of elastic material for the elastic protrusion can be optimized according to different tissue characteristics and surgical requirements to ensure the best closure effect. For example, when dealing with harder tissue, a harder elastic material can be selected; when dealing with soft or fragile tissue, a more flexible material can be selected.

[0120] In summary, by providing the elastic protrusion and the recess, the pull wire member 300 can switch between the compressed and expanded states, thereby providing a solution that is both convenient to operate and safe and reliable, and is particularly suitable for complex endoscopic surgical scenarios.

[0121] like Fig.11 and Fig.12 As shown, in some embodiments, the outer wall of the wire pulling member 300 is provided with a groove 330, the groove 330 is extended along the circumference of the wire pulling member 300, and the recessed portion is provided in the groove 330;

[0122] The raised portion includes a plurality of elastic strips 320, which are arranged at intervals along the circumference of the wire pulling member 300, one end of the elastic strip 320 is connected to one side of the groove 330, the other end of the elastic strip 320 is connected to the other side of the groove 330, and the middle part of the elastic strip 320 is arched in the direction away from the wire pulling member 300.

[0123] In these embodiments, the outer wall of the wire puller 300 is provided with grooves 330, which extend along the circumference of the wire puller 300. The existence of the grooves 330 provides a space for placing the elastic strip 320 and helps to maintain the position of the elastic strip 320. The recessed portion is provided in the groove 330. When the wire puller 300 is in a compressed state, the elastic strip 320 will be pressed into the recessed portion, so that the overall outer diameter of the wire puller 300 is reduced, so that it can pass through the puncture sleeve 100 smoothly.

[0124] The raised portion is composed of a plurality of elastic strips 320, which are arranged at intervals along the circumference of the wire puller 300. One end of each elastic strip 320 is connected to one side of the groove 330, and the other end is connected to the other side of the groove 330. The middle part of the elastic strip 320 is arched in the direction away from the wire puller 300 to form a raised structure. This arched design allows the elastic strip 320 to expand naturally when not subjected to external force, and can be compressed into the recessed portion when subjected to external force (such as passing through the puncture sleeve 100).

[0125] Obviously, when the wire puller 300 needs to pass through the puncture sleeve 100, the elastic strip 320 can be compressed into the recessed portion in the groove 330 to reduce the overall outer diameter and facilitate movement. Once the wire puller 300 extends from the distal end 110 of the puncture sleeve 100, the elastic strip 320 will naturally restore its arched shape, so that the maximum outer diameter of the wire puller 300 is greater than the inner diameter of the puncture sleeve 100 to prevent retreat. In other words, in the expanded state, the additional support force provided by the elastic strip 320 can ensure that the wire puller 300 is firmly fixed in the target position, improving the stability and reliability of the closing operation. Because the elastic strips 320 are flexible, they can provide a certain buffering effect when contacting tissue, reducing potential damage to surrounding healthy tissue.

[0126] For example, the elastic strip 320 is a thin sheet structure, and the elastic strip 320 is easily deformed. In contrast, there is a concave groove 330 corresponding to the surface of the wire puller 300. When the wire puller 300 is in the puncture sleeve 100, the elastic strip 320 is pressed into the groove 330; when the wire puller 300 is outside the puncture sleeve 100, the elastic strip 320 bulges and expands the total outer diameter of the wire puller 300, preventing the wire puller 300 from being pulled into the puncture sleeve 100 again.

[0127] like Fig.13 and Fig.14As shown, in some embodiments, a threading hole 410 is provided at one end of the release member 400, and the other end of the release member 400 is connected to the drive guide wire 500; wherein, the hole wall of the threading hole 410 is provided with a breakable area, and the breaking of the breakable area can cause the hole wall of the threading hole 410 to form a non-closed structure.

[0128] In these embodiments, by driving the operation of the guide wire 500, the position and movement of the release member 400 can be controlled, thereby adjusting the tightness of the suture 600. The fragile zone is a pre-set weak point or pre-cut on the wall of the threading hole 410, and its strength is lower than other parts of the hole wall. When necessary, the fragile zone can be broken by applying a certain force (such as pulling or shearing), so that the hole wall of the threading hole 410 forms a non-closed structure. The non-closed structure is formed to facilitate the release of the suture 600, that is, once the fragile zone breaks, the threading hole 410 will no longer be completely closed, which makes it easier for the suture 600 to detach from the hole. This is very useful for rapid disassembly after the end of the operation or rapid processing in an emergency. And there is no need to use other auxiliary cutting instruments to cut the suture 600 after the incision is closed, which is convenient for surgical operation. That is, when the suture 600 needs to be released, it only needs to apply appropriate force without additional tools or complicated steps.

[0129] Exemplarily, a second wire fixing hole 440 is provided at one end of the release member 400 away from the threading hole 410, and the end of the driving guide wire 500 passes through the second wire fixing hole 440 and is fixed by applying glue.

[0130] like Fig.13 and Fig.14 As shown, in some embodiments, the breakable area is provided with a breaking groove 420 , and the breaking groove 420 extends from one end surface of the threading hole 410 to the other end surface.

[0131] In these embodiments, the rupture groove 420 provides a clear rupture path for the hole wall of the threading hole 410. When the threading hole 410 needs to be formed into a non-closed structure, the rupture will occur along the preset rupture groove 420, thereby ensuring that the rupture occurs at the expected position. The pre-set rupture groove 420 can more accurately control the rupture process. This allows the doctor to release the suture 600 more reliably during the operation, improving the controllability and predictability of the operation.

[0132] The design of the rupture groove 420 reduces the risk of accidental damage caused by irregular rupture. Without the rupture groove 420, the hole wall may break at any weak point, resulting in uncontrollable situations. Due to the presence of the rupture groove 420, only appropriate force is required to break the fragile area. This simplifies the operation steps of releasing the suture 600, and no additional tools or complicated actions are required.

[0133] It should be noted that during the manufacturing process, the fracture groove 420 can be created by precision machining techniques (such as laser cutting, micromachining, etc.). These techniques can ensure that the size and position of the fracture groove 420 are highly accurate to meet the requirements of clinical applications. In order to ensure the effectiveness of the fracture groove 420, the material used needs to have a certain degree of brittleness so that it can be accurately broken when subjected to a predetermined force. At the same time, the material also needs to have good biocompatibility and mechanical strength to ensure the overall performance of the device.

[0134] like Fig.13 and Fig.14 As shown, in some embodiments, the end surface of one end of the release member 400 provided with a threading hole 410 is provided with an open groove 430 , and the threading hole 410 passes through two groove walls of the open groove 430 .

[0135] In these embodiments, the provision of the opening groove 430 is beneficial to reducing the structural strength of the side wall of the threading hole 410, thereby facilitating the breaking of the fragile area.

[0136] For example, the number of the opening slot 430 is one. Of course, in other embodiments, the number of the opening slot 430 may also be two, three, four, five, etc.

[0137] In all examples shown and described herein, any specific values ​​should be interpreted as merely exemplary and not as limiting, and thus other examples of the exemplary embodiments may have different values.

[0138] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0139] The above-mentioned embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application.

Claims

1. A tissue closure device, characterized in that: The tissue closure device comprises a puncture sleeve, a suture, a pair of fixing members, a wire puller, a release member and a drive guide wire, wherein the pair of fixing members, the wire puller, the release member and the drive guide wire are respectively movably arranged in the puncture sleeve; wherein the puncture sleeve has a distal end and a proximal end, the distal end is arranged as a tip, and the pair of fixing members, the wire puller, the release member and the drive guide wire are arranged in sequence from the distal end to the proximal end; The release member is connected to the drive guide wire, and the drive guide wire can drive the release member to move along the axial direction of the puncture sleeve; wherein the release member has a threading hole, and the suture is passed through the threading hole; The wire pulling member has a wire tightening hole, and the two ends of the suture are inserted into the wire tightening hole in the same direction. The hole wall of the wire tightening hole exerts a clamping force on the suture, and the clamping force is less than the breaking strength of the suture; One of the pair of fixing members is connected to one end of the suture, and the other of the pair of fixing members is connected to the other end of the suture.

2. The tissue closure according to claim 1, characterized in that: The tip is provided with a cutting edge.

3. The tissue closure device according to claim 1, characterized in that: The fixing member has a head end and a tail end, the head end is close to the distal end, and the tail end is far away from the distal end. The outer wall of the tail end of the fixing member is provided with a plurality of storage grooves, and the plurality of storage grooves extend from the end surface of the tail end toward the head end. The tail end is connected to one end of the suture, and the connection between the suture and the tail end is located in the storage groove.

4. The tissue closure according to claim 3, characterized in that: A receiving groove is also provided in the middle of the end surface of the tail end, and the receiving groove is extended from the end surface of the tail end toward the head end, and the storage groove and the receiving groove are communicated with each other.

5. The tissue closure according to claim 4, characterized in that: The side wall of the fixing member is provided with a wire groove, and the wire groove extends from the end surface of the head end to the end surface of the tail end; And / or, the end surface of the head end of the fixing member is provided with a wire passing hole, and the wire passing hole extends from the end surface of the head end to the bottom of the accommodating groove.

6. The tissue closure device according to claim 3, characterized in that: The portion of the fixing member located between the adjacent placement grooves is configured as an elastic structure, and the initial outer diameter of the portion of the fixing member located in the placement groove is greater than the inner diameter of the puncture sleeve.

7. The tissue closure according to claim 6, characterized in that: The outer wall of the tail end has a flange portion, and the initial outer diameter of the flange portion is larger than the inner diameter of the puncture sleeve.

8. The tissue closure according to claim 1, characterized in that: The two ends of the suture thread are passed through the same tightening hole; Alternatively, the two ends of the suture thread are respectively inserted into different tightening holes, and the suture thread and the tightening hole are transitionally matched.

9. The tissue closure according to claim 1 or 8, characterized in that: The inner wall of the tightening hole is provided with barbs, and the barbs are biased toward an end of the tightening hole away from the fixing member.

10. The tissue closure according to claim 1, wherein: The outer wall of the pull wire piece is provided with an elastic protrusion and a recessed portion. The pull wire piece enters and exits the puncture sleeve so that the elastic protrusion can switch between a compressed state located inside the recessed portion and an expanded state located outside the recessed portion; wherein, in the expanded state, the maximum outer diameter of the pull wire piece is greater than the inner diameter of the puncture sleeve.

11. The tissue closure according to claim 10, characterized in that: The outer wall of the wire pulling member is provided with a groove, the groove is extended along the circumference of the wire pulling member, and the recessed portion is provided in the groove; The raised portion includes a plurality of elastic strips, which are arranged at intervals along the circumference of the wire pulling member, one end of the elastic strip is connected to one side of the groove, the other end of the elastic strip is connected to the other side of the groove, and the middle part of the elastic strip is arched in the direction away from the wire pulling member.

12. The tissue closure according to claim 1, wherein: One end of the release member is provided with the threading hole, and the other end of the release member is connected to the drive guide wire; wherein, the hole wall of the threading hole is provided with a breakable area, and the breaking of the breakable area can cause the hole wall of the threading hole to form a non-closed structure.

13. The tissue closure according to claim 12, characterized in that: The breakable area is provided with a breaking groove, and the breaking groove extends from one end surface of the threading hole to the other end surface.

14. The tissue closure according to claim 12, characterized in that: An end surface of one end of the release member having the threading hole is provided with an open groove, and the threading hole passes through two groove walls of the open groove.

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