Irradiation equipment for skin failure light experiment

By designing an annular runway that allows mice to move freely in the irradiation equipment and an irradiation equipment that automatically feeds feed, the anxiety and hunger problems caused by fixation in traditional experiments were solved, and the reliability of experimental data was improved and shortened. Experimental cycle.

CN119214823AInactive Publication Date: 2024-12-31THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV
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Patent Information

Application Number
CN202411769383.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-04
Publication Date
2024-12-31
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In traditional skin failure light experiments, mice caused anxiety and tension due to fixed devices, which affected the functions of the endocrine and immune system. They did not feed for a long time and resulted in hunger, unable to maintain a normal physiological state, and prolonged the experimental cycle.

Method used

Design an irradiation device, including an ultraviolet irradiation instrument, a placement mechanism and a temperature monitoring device. The placement mechanism allows the mice to move freely through an annular runway surrounded by the outer ring body and the built-in cylinder body. It will automatically feed the feed to reduce the amount of time. Invigorate the reaction and prolong the experiment time.

Benefits of technology

Mice can keep moving freely during the experiment, reduce stress response, improve the reliability of experimental data, and shorten the experimental cycle by automatically feeding feed to obtain more sample data.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of light aging experiment equipment, in particular to irradiation equipment for a skin failure light experiment, which comprises an ultraviolet irradiation instrument, a placement mechanism arranged on the inner bottom surface of the ultraviolet irradiation instrument and a temperature monitoring device arranged above the placement mechanism, and the temperature monitoring device comprises an infrared imager for observing the temperature distribution condition of the skin of the mouse below. According to the irradiation equipment for the skin failure light experiment, the annular runway defined by the outer sleeve ring body and the built-in cylinder body is matched with the limiting part, so that a mouse can move freely in the experiment process under the condition that back skin irradiation is not affected, the mode of binding the mouse in a traditional experiment is avoided, and the experiment efficiency is improved. Therefore, the possibility of stress reaction of the mouse in the experiment process is reduced, and the reliability of experiment data is further improved.
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Description

Technical Field

[0001] The invention relates to the technical field of photoaging experimental equipment, in particular to an irradiation device used for skin failure light experiment. Background Art

[0002] In photoaging experiments, ultraviolet irradiation equipment is usually used to accurately simulate and accelerate the aging process of materials or organisms under natural light conditions and to ensure the controllability and repeatability of experimental conditions. In order to allow the experimental subjects to more effectively simulate the process of photofailure of human skin, mice with genes and skin structures that are highly similar to humans are usually used as experimental subjects.

[0003] The patent with application number CN202320449251.2 discloses an ultraviolet irradiation test device, a box body and an ultraviolet irradiation component. A test chamber with an opening on the top is provided inside the box body, a top cover is provided at the opening of the test chamber, a water tank is provided at the bottom of the test chamber, a heating device is provided in the water tank, a sample placement table is installed above the water tank, a sample is placed on the sample placement table, the ultraviolet irradiation component is arranged on the inner wall of the test chamber, and the ultraviolet irradiation component is located above the sample, which can effectively simulate the environmental conditions in the natural climate to conduct accelerated weather resistance tests on the test materials, and has a simple structure and is easy to assemble and disassemble.

[0004] In traditional skin failure photoaging experiments, in order to limit the movement of mice during the experiment, special fixing devices are usually needed to fix the mice. However, the use of fixing devices may cause the mice to feel anxious and nervous due to fixation, which in turn affects the function of their endocrine and immune systems, thereby having a certain impact on the experimental results. In addition, in traditional experiments, long-term non-feeding will cause the mice to starve and lose physical strength. In this case, the mice cannot maintain a normal physiological state, and effective skin failure photoaging experiments cannot be carried out. Therefore, it is necessary to conduct skin failure photoaging experiments on mice for a long time and multiple times, but this will extend the overall cycle of the experiment.

[0005] In view of this, we propose an irradiation device for skin failure photoexperiments. Summary of the invention

[0006] The object of the present invention is to provide an irradiation device for skin failure light experiment to solve the problems raised in the above background technology.

[0007] To achieve the above object, the present invention provides the following technical solutions: An irradiation device for skin failure light experiment, comprising an ultraviolet irradiator, a placement mechanism arranged on the bottom surface of the ultraviolet irradiator, and a temperature monitoring device arranged above the placement mechanism, wherein the temperature monitoring device comprises an infrared imager for observing the temperature distribution of the mouse skin below; The ultraviolet irradiation device comprises a fixed body with an open front end and a plurality of fixed lamp tubes regularly distributed on the top surface of the fixed body for irradiating ultraviolet rays to the mouse skin; The placement mechanism includes a drawing mechanism, a placement cage arranged on the top surface of the drawing mechanism, a limiting part arranged on the top surface of the placement cage, a moving part arranged inside the placement cage, and a feeding mechanism whose internal structure moves with the movement of the moving part; The placement cage comprises an outer ring body, an inner cylinder body arranged inside the outer ring body, a plurality of steel wires regularly connected between the outer ring body and the inner cylinder body, and a central truncated cone arranged on the inner ring wall of the inner cylinder body; The moving part comprises an arc-shaped slide plate, a plate wall rack arranged on the inner side ring wall of the arc-shaped slide plate, and an elastic ring for sleeved on the neck of the mouse; The feeding mechanism includes a rotating disc, disc wall ring teeth sleeved on the outer ring wall of the rotating disc, a material storage barrel arranged above the rotating disc, a material guide platform arranged on the inner bottom surface of the material storage barrel, and docking gears arranged on the left and right sides of the rotating disc.

[0008] In the technical solution of the present invention, a limiting slide groove connected to the outer wall of the fixed body is opened on the inner top surface of the fixed body, and a sealing flap is rotatably connected to the outer bottom of the open front end of the fixed body. The fixed lamp tube is fixedly connected to the inner top surface of the fixed body by screws.

[0009] In the technical solution of the present invention, the pull-out mechanism includes a movable platform placed on the bottom surface of the fixed body and a pull-out box slidably connected to the inside of the movable platform. A circular table hole that passes through from top to bottom is opened at the center position of the top surface of the movable platform.

[0010] In the technical solution of the present invention, the outer ring body is clamped and fixed on the top surface of the mobile platform, the inner cylinder body is welded and fixed on the inner top surface of the outer ring body, and cylinder wall grooves are provided on the top surfaces of the left and right ends of the inner cylinder body, and the two ends of the steel wire strip are respectively welded and fixed to the inner wall of the outer ring body and the outer wall of the inner cylinder body.

[0011] In the technical solution of the present invention, the central cone is welded and fixed to the inner wall of the built-in cylinder, and a material guide groove connected to the front end wall of the built-in cylinder is provided on the top surface of the central cone circular plate near the front end, and several of the steel wire strips are clamped with arc-shaped connecting plates in the groove below the material guide groove.

[0012] In the technical solution of the present invention, the limiting portion includes an outer ring bar and an inner ring bar, both of which are L-shaped in longitudinal cross-section, and a number of regularly distributed connecting strips are welded between the outer ring bar and the inner ring bar. The bottom surfaces of the left and right ends of the inner ring bar are provided with strip bottom grooves corresponding to the positions of the cylinder wall grooves, and the outer ring bar and the inner ring bar are respectively clamped and fixed on the top surfaces of the outer ring body and the inner cylinder body.

[0013] In the technical solution of the present invention, the arc-shaped slide plate is slidably connected between the outer ring body and the inner cylinder body, the top surface of the arc-shaped slide plate is provided with a plate surface through groove which passes through from top to bottom, the plate wall rack is welded and fixed to the arc-shaped slide plate, and the elastic ring is adhesively fixed to the bottom surface of the arc-shaped slide plate.

[0014] In the technical solution of the present invention, the rotating disc is rotatably connected to the top surface of the central cone, and a disc body through hole corresponding to the position of the top notch of the material guide groove and passing through the top and bottom is opened on the top surface of the rotating disc, and the disc wall ring teeth are welded and fixed to the outer wall of the rotating disc, and the material storage barrel is fixed to the top surface of the central cone after passing through the rotating disc through the round rod at the bottom.

[0015] In the technical solution of the present invention, a material discharge hole is provided on the bottom wall of the material storage barrel, which passes through the upper and lower parts and is connected to the through hole of the disk body. The material guide platform is integrally formed with the material storage barrel. A fixed rod is provided inside the docking gear, and the docking gear is rotatably connected to the outer wall of the fixed rod. The docking gear is respectively meshed with the disk wall ring gear and the plate wall rack.

[0016] In the technical solution of the present invention, the infrared imager is slidably connected to the inside of the limiting slide groove, and the temperature monitoring device also includes a pull-out plate fixed on the outer groove wall of the limiting slide groove and a connecting rod connected between the infrared imager and the pull-out plate.

[0017] Compared with the prior art, the present invention has the following beneficial effects: 1. The irradiation equipment used for skin failure light experiment, through the circular track surrounded by the outer ring body and the inner cylinder, cooperates with the limiting part, so that the mice can move freely during the experiment without affecting the irradiation of the back skin, avoiding the way of restraining mice in traditional experiments, thereby reducing the possibility of stress response in mice during the experiment, and then improving the reliability of experimental data.

[0018] 2. In the irradiation equipment used for skin failure light experiments, when mice move in the circular track surrounded by the outer ring body and the inner cylinder, the plate wall rack can drive the structure in the feeding mechanism to move, and a certain amount of feed can be delivered to the top of the arc-shaped connecting plate, thereby extending the time for a single experimental observation, which is helpful to obtain more diverse experimental data and shorten the experimental cycle. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0020] Figure 2 It is a schematic diagram of the overall structure of the present invention.

[0021] Figure 3 It is a schematic cross-sectional view of the structure of the ultraviolet irradiator in the present invention.

[0022] Figure 4 It is a structural schematic diagram of the placement mechanism in the present invention.

[0023] Figure 5 It is a schematic diagram of the structural disassembly of the drawing and pulling mechanism in the present invention.

[0024] Figure 6 It is a partial structural schematic diagram of the placement mechanism in the present invention.

[0025] Figure 7 It is a schematic cross-sectional view of the structure of the placement cage in the present invention.

[0026] Figure 8 It is a schematic diagram of the structure of the limiting part in the present invention.

[0027] Fig. 9 It is a structural schematic diagram of the moving part in the present invention.

[0028] Fig.10 It is a schematic cross-sectional view of the structure of the feeding mechanism in the present invention.

[0029] Fig.11 It is a partial structural schematic diagram of the feeding mechanism in the present invention.

[0030] Fig.12 It is a schematic diagram of the structure of the temperature monitoring device in the present invention.

[0031] Description of reference numerals: 100, ultraviolet irradiator; 110, fixed body; 111, limit slide; 120, sealing flap; 130, fixed lamp tube; 200, placement mechanism; 210, drawing mechanism; 211, mobile platform; 2110, table top round hole; 212, drawing box; 220, placement cage; 221, outer ring body; 222, built-in cylinder; 2220, cylinder wall groove; 223, steel wire; 224, arc connecting plate; 225, center round table; 2250, guide groove; 230, limit part; 231, outer ring strip; 232, inner ring strip; 2 320, groove at the bottom of the strip; 233, connecting strip; 240, moving part; 241, arc-shaped slide plate; 2410, through groove on the board surface; 242, rack on the board wall; 243, elastic ring; 250, feeding mechanism; 251, rotating disc; 2510, through hole on the disc body; 252, ring gear on the disc wall; 253, material storage barrel; 2530, material discharge hole; 254, material guide platform; 255, fixing rod; 256, docking gear; 300. Temperature monitoring device; 310. Infrared imager; 320. Pull-out plate; 330. Connecting rod. DETAILED DESCRIPTION

[0032] The following will be combined with the accompanying drawings in the present invention to clearly and completely describe the technical solutions in the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0033] See also Figure 1-Figure 12 As shown, this embodiment provides a technical solution: An irradiation device for skin failure light experiment, comprising an ultraviolet irradiator 100, a placement mechanism 200 arranged on the bottom surface of the ultraviolet irradiator 100, and a temperature monitoring device 300 arranged above the placement mechanism 200, wherein the temperature monitoring device 300 comprises an infrared imager 310 for observing the temperature distribution of the mouse skin below; In this embodiment, Figure 3 As shown, the ultraviolet irradiation device 100 includes a fixed body 110 with an open front end and a plurality of fixed lamp tubes 130 regularly distributed on the top surface of the fixed body 110 for irradiating the mouse skin with ultraviolet rays; Specifically, a limiting slide groove 111 connected to the outer wall of the fixed body 110 is opened on the inner top surface of the fixed body 110, and a sealing flap 120 is rotatably connected to the outer bottom of the open front end of the fixed body 110, and the fixed lamp tube 130 is fixedly connected to the inner top surface of the fixed body 110 by screws.

[0034] Furthermore, the fixed body 110 is used to ensure the strength of the overall structure of the ultraviolet irradiator 100, the sealing flap 120 is used to ensure the airtightness of the internal structure of the fixed body 110, the fixed lamp tube 130 is used to irradiate ultraviolet rays to the mouse's skin, and the limiting slide groove 111 is used to provide a sliding range for the temperature monitoring device 300.

[0035] In this embodiment, Figure 4-Figure 5 As shown, the placement mechanism 200 includes a drawing mechanism 210, a placement cage 220 disposed on the top surface of the drawing mechanism 210, a limiting portion 230 disposed on the top surface of the placement cage 220, a moving portion 240 disposed inside the placement cage 220, and a feeding mechanism 250 whose internal structure moves as the moving portion 240 moves; Specifically, the pull-out mechanism 210 includes a movable platform 211 placed on the bottom surface of the fixed body 110 and a pull-out box 212 slidably connected to the inside of the movable platform 211 . A table circular hole 2110 that passes through the top and bottom is opened at the center position of the top surface of the movable platform 211 .

[0036] Furthermore, the mobile platform 211 is used to provide a placement area for the cage 220 , the drawer box 212 is used to facilitate the cleaning of garbage caused by mice during the experiment, and the circular hole 2110 on the table is used to facilitate the falling of garbage in the cage 220 .

[0037] In this embodiment, Figure 6-Figure 7 As shown, the placement cage 220 includes an outer ring body 221, an inner cylinder body 222 disposed inside the outer ring body 221, a plurality of connecting strips 233 regularly connected between the outer ring body 221 and the inner cylinder body 222, and a central truncated cone 225 disposed on the inner ring wall of the inner cylinder body 222; Specifically, the outer ring body 221 is clamped and fixed on the top surface of the mobile platform 211, and the inner cylinder 222 is welded and fixed on the inner top surface of the outer ring body 221. The top surfaces of the left and right ends of the inner cylinder 222 are provided with cylinder wall grooves 2220, and the two ends of the steel wire 223 are respectively welded and fixed to the inner wall of the outer ring body 221 and the outer wall of the inner cylinder 222.

[0038] Furthermore, the central cone 225 is welded and fixed to the inner wall of the built-in cylinder 222, and a material guide groove 2250 connected to the front end wall of the built-in cylinder 222 is opened on the top surface of the circular plate of the central cone 225 near the front end, and a plurality of steel wire strips 223 are clamped with an arc-shaped connecting plate 224 in the groove below the material guide groove 2250.

[0039] Furthermore, the outer ring body 221 cooperates to ensure the strength of the overall structure of the inner cylinder 222. The circular runway formed by the outer ring body 221 and the inner cylinder 222 is used to allow the mice to move during the experiment. The steel wire strip 223 is used to allow the feces of the mice to fall below the circular hole 2110 on the table. The arc-shaped connecting plate 224 is used to store feeding feed, and the central frustum 225 is used to provide a placement platform for the feeding mechanism 250.

[0040] In this embodiment, Figure 8 As shown, the limiting portion 230 includes an outer ring strip 231 and an inner ring strip 232, both of which are L-shaped in longitudinal cross-section. A number of regularly distributed connecting strips 233 are welded between the outer ring strip 231 and the inner ring strip 232. The bottom surfaces of the left and right ends of the inner ring strip 232 are provided with strip bottom grooves 2320 corresponding to the positions of the cylinder wall grooves 2220. The outer ring strip 231 and the inner ring strip 232 are respectively clamped and fixed on the top surfaces of the outer ring body 221 and the inner cylinder body 222. Furthermore, the inner ring strip 232 is used to connect the outer ring strip 231 and the inner ring strip 232. After the outer ring strip 231 and the inner ring strip 232 are snapped onto the top surfaces of the outer ring body 221 and the inner cylinder body 222, they are used to limit the position of the moving part 240, so that the mouse can only move within the circular runway surrounded by the outer ring body 221 and the inner cylinder body 222, so that when the mouse moves, only the back is exposed under the fixed lamp tube 130, and the cylinder wall groove 2220 is used to provide a contact area between the structure in the feeding mechanism 250 and the structure inside the moving part 240.

[0041] In this embodiment, Fig. 9 As shown, the moving part 240 includes an arc-shaped slide plate 241, a plate wall rack 242 arranged on the inner side ring wall of the arc-shaped slide plate 241, and an elastic ring 243 for being set on the neck of the mouse; Specifically, the arc-shaped slide plate 241 is slidably connected between the outer ring body 221 and the inner cylinder body 222 , the top surface of the arc-shaped slide plate 241 is provided with a plate surface through groove 2410 which passes through from top to bottom, the plate wall rack 242 is welded and fixed to the arc-shaped slide plate 241 , and the elastic ring 243 is adhesively fixed to the bottom surface of the arc-shaped slide plate 241 .

[0042] Furthermore, the plate groove 2410 on the top surface of the arc-shaped slide plate 241 is used to expose the skin on the back of the mouse to the bottom of the fixed lamp tube 130, and the plate wall rack 242 is used to contact the structure in the feeding mechanism 250. In the experiment, the head of the mouse and one of its front paws are placed inside the elastic ring 243, so that when the mouse moves, it can drive the arc-shaped slide plate 241 to move together.

[0043] In this embodiment, Figure 10-11As shown, the feeding mechanism 250 includes a rotating disc 251, a disc wall ring gear 252 sleeved on the outer ring wall of the rotating disc 251, a material storage barrel 253 arranged above the rotating disc 251, a material guide platform 254 arranged on the inner bottom surface of the material storage barrel 253, and a docking gear 256 arranged on the left and right sides of the rotating disc 251; Specifically, the rotating disc 251 is rotatably connected to the top surface of the central truncated platform 225. A disc through hole 2510 corresponding to the top notch of the material guide groove 2250 and penetrating from top to bottom is provided on the top surface of the rotating disc 251. The disc wall ring gear 252 is welded and fixed to the outer wall of the rotating disc 251. The material storage barrel 253 is fixed to the top surface of the central truncated platform 225 after passing through the rotating disc 251 through the round rod at the bottom. Furthermore, a discharge hole 2530 is provided on the bottom wall of the material storage barrel 253, which passes through from top to bottom and is connected to the through hole 2510 of the disk body. The material guide platform 254 is integrally formed with the material storage barrel 253. A fixed rod 255 is provided inside the docking gear 256, and the docking gear 256 is rotatably connected to the outer wall of the fixed rod 255. The docking gear 256 is respectively meshed with the disk wall ring gear 252 and the plate wall rack 242.

[0044] Furthermore, during the light experiment, the experimental mice walked in the circular track between the outer ring body 221 and the inner cylinder body 222, which drove the arc-shaped slide plate 241 to move. When the plate wall rack 242 collided with the docking gear 256, the docking gear 256 was driven to rotate, and the disk wall ring gear 252 and the rotating disk 251 were driven to rotate. After the disk body through hole 2510 of the rotating disk 251 moves to the bottom of the material guide groove 2250, a certain amount of feed will fall into the inside of the disk body through hole 2510, and when the disk body through hole 2510 moves to the top of the material guide groove 2250 along with the rotating disk 251, the feed will immediately fall from the material guide groove 2250 to the top surface of the arc-shaped connecting plate 224.

[0045] In this embodiment, Fig.12 As shown, the infrared imager 310 is slidably connected to the inside of the limiting slide groove 111, and the temperature monitoring device 300 also includes a pull-out plate 320 fixed on the outer groove wall of the limiting slide groove 111 and a connecting rod 330 connected between the infrared imager 310 and the pull-out plate 320; Furthermore, the infrared imager 310 is used to observe the temperature distribution of the skin on the back of the mouse in real time during the light experiment, and the infrared imager 310 can be quickly pulled out of the interior of the fixed body 110 by driving the pull-out plate 320 to move.

[0046] Finally, it should be noted that the fixed lamp tube 130 and infrared imager 310 involved in the present invention are universal standard parts or parts known to technical personnel in this field, and their structures and principles are known to technical personnel in this field through technical manuals or conventional experimental methods. In the idle space of this device, the fixed lamp tube 130 and the infrared imager 310 are connected to the external power supply through wires. The specific connection method should refer to the working principle of the present invention. The electrical connection between each electrical component is completed in a sequential working order, and the detailed connection methods are all well-known technologies in this field.

[0047] When the irradiation device for skin failure light experiment of the present invention is used, first, the intensity of the ultraviolet light irradiated by the fixed lamp tube 130 in the ultraviolet irradiator 100 is determined, and the sealing flap 120 is opened; Next, the hair on the back of the mouse used for the skin failure light experiment is removed, and the head and one of the front paws of the mouse are placed inside the elastic ring 243 in the moving part 240 of the placement mechanism 200; Subsequently, the arc-shaped slide plate 241 is placed together with the arc-shaped slide plate 241 in the annular runway between the outer ring body 221 and the inner cylinder body 222 in the placement cage 220, and the limiting portion 230 is integrally buckled on the top of the outer ring body 221 and the inner cylinder body 222; Afterwards, the placement mechanism 200 is placed as a whole on the inner bottom surface of the fixed body 110, and after the sealing flap 120 is closed, the fixed lamp tube 130 and the infrared imager 310 in the temperature monitoring device 300 are turned on; During the experiment, the mice walked in the circular track between the outer ring body 221 and the inner cylinder body 222, which drove the arc-shaped slide plate 241 to move. When the plate wall rack 242 collided with the docking gear 256, the docking gear 256 was driven to rotate, and the disk wall ring gear 252 and the rotating disk 251 were driven to rotate. After the disk body through hole 2510 of the rotating disk 251 moves to the bottom of the material guide groove 2250, a certain amount of feed will fall into the inside of the disk body through hole 2510, and when the disk body through hole 2510 moves to the top of the material guide groove 2250 along with the rotating disk 251, the feed will immediately fall from the material guide groove 2250 to the top surface of the arc-shaped connecting plate 224.

[0048] The foregoing description of specific exemplary embodiments of the present invention is for the purpose of illustration and demonstration. These descriptions are not intended to limit the present invention to the precise form disclosed, and it is clear that many changes and variations can be made based on the above teachings. The purpose of selecting and describing exemplary embodiments is to explain the specific principles of the present invention and its practical application, so that those skilled in the art can realize and utilize various different exemplary embodiments of the present invention and various different selections and changes. The scope of the present invention is intended to be limited by the specification and its equivalents.

Claims

1. An irradiation device for a skin failure light experiment, comprising an ultraviolet irradiator (100), a placement mechanism (200) disposed on the bottom surface of the ultraviolet irradiator (100), and a temperature monitoring device (300) disposed above the placement mechanism (200), wherein the temperature monitoring device (300) comprises an infrared imager (310) for observing the temperature distribution of the mouse skin below; Features: The ultraviolet irradiation device (100) comprises a fixed body (110) with an open front end and a plurality of fixed lamp tubes (130) regularly distributed on the top surface of the fixed body (110) and used for irradiating the mouse skin with ultraviolet rays; The placement mechanism (200) comprises a drawing mechanism (210), a placement cage (220) arranged on the top surface of the drawing mechanism (210), a limiting portion (230) arranged on the top surface of the placement cage (220), a moving portion (240) arranged inside the placement cage (220), and a feeding mechanism (250) whose internal structure moves as the moving portion (240) moves; The placement cage (220) comprises an outer ring body (221), an inner cylinder body (222) arranged inside the outer ring body (221), a plurality of steel wires (223) regularly connected between the outer ring body (221) and the inner cylinder body (222), and a central truncated cone (225) arranged on the inner ring wall of the inner cylinder body (222); The moving part (240) comprises an arc-shaped slide plate (241), a plate wall rack (242) arranged on the inner side ring wall of the arc-shaped slide plate (241), and an elastic ring (243) for being sleeved on the neck of a mouse; The feeding mechanism (250) comprises a rotating disc (251), a disc wall ring gear (252) sleeved on the outer ring wall of the rotating disc (251), a material storage barrel (253) arranged above the rotating disc (251), a material guide platform (254) arranged on the inner bottom surface of the material storage barrel (253), and docking gears (256) arranged on the left and right sides of the rotating disc (251).

2. The irradiation device for skin failure light experiment according to claim 1 is characterized in that: A limiting slide groove (111) is provided on the internal top surface of the fixed body (110) and is connected to the outer wall of the fixed body (110); a sealing flap (120) is rotatably connected to the outer bottom of the front open end of the fixed body (110); and the fixed lamp tube (130) is fixedly connected to the internal top surface of the fixed body (110) by means of screws.

3. The irradiation device for skin failure light experiment according to claim 1 is characterized in that: The drawer mechanism (210) comprises a movable platform (211) placed on the bottom surface of the fixed body (110) and a drawer box (212) slidably connected to the inside of the movable platform (211); a table top circular hole (2110) penetrating from top to bottom is provided at the center of the top surface of the movable platform (211).

4. The irradiation device for skin failure light experiment according to claim 1 is characterized in that: The outer ring body (221) is fixedly connected to the top surface of the mobile platform (211), the inner cylinder (222) is fixedly connected to the inner top surface of the outer ring body (221) by welding, and cylinder wall grooves (2220) are provided on the top surfaces of the left and right ends of the inner cylinder (222), and the two ends of the steel wire (223) are respectively fixedly connected to the inner wall of the outer ring body (221) and the outer wall of the inner cylinder (222).

5. The irradiation device for skin failure light experiment according to claim 1 is characterized in that: The central truncated cone (225) is welded and fixed to the inner wall of the built-in cylinder (222); a material guide groove (2250) connected to the front wall of the built-in cylinder (222) is provided on the top surface of the circular plate of the central truncated cone (225) near the front end; and a plurality of the steel wire strips (223) are clamped with arc-shaped connecting plates (224) at the groove below the material guide groove (2250).

6. The irradiation device for skin failure light experiment according to claim 4 is characterized in that: The limiting portion (230) comprises an outer ring strip (231) and an inner ring strip (232) both of which are L-shaped in longitudinal cross-section; a plurality of regularly distributed connecting strips (233) are welded between the outer ring strip (231) and the inner ring strip (232); the bottom surfaces of the left and right ends of the inner ring strip (232) are provided with strip bottom grooves (2320) corresponding to the positions of the cylinder wall grooves (2220); the outer ring strip (231) and the inner ring strip (232) are respectively clamped and fixed on the top surfaces of the outer ring body (221) and the inner cylinder body (222).

7. The irradiation device for skin failure light experiment according to claim 1 is characterized in that: The arc-shaped slide plate (241) is slidably connected between the outer ring body (221) and the inner cylinder body (222); a plate surface through groove (2410) which passes through the top and bottom is provided on the top surface of the arc-shaped slide plate (241); the plate wall rack (242) is welded and fixed to the arc-shaped slide plate (241); and the elastic ring (243) is adhesively fixed to the bottom surface of the arc-shaped slide plate (241).

8. The irradiation device for skin failure light experiment according to claim 5 is characterized in that: The rotating disk (251) is rotatably connected to the top surface of the central truncated platform (225); a disk body through hole (2510) corresponding to the top notch position of the material guide groove (2250) and penetrating from top to bottom is provided on the top surface of the rotating disk (251); the disk wall ring teeth (252) are welded and fixed to the outer wall of the rotating disk (251); and the material storage barrel (253) is fixed to the top surface of the central truncated platform (225) after passing through the rotating disk (251) through the round rod at the bottom.

9. The irradiation device for skin failure light experiment according to claim 8, characterized in that: A material discharge hole (2530) is provided on the bottom wall of the material storage barrel (253) and is connected to the through hole (2510) of the disc body. The material guide platform (254) is integrally formed with the material storage barrel (253). A fixing rod (255) is provided inside the docking gear (256). The docking gear (256) is rotatably connected to the outer wall of the fixing rod (255). The docking gear (256) is respectively meshed with the disc wall ring gear (252) and the plate wall rack (242).

10. The irradiation device for skin failure light experiment according to claim 1, characterized in that: The infrared imager (310) is slidably connected to the interior of the limiting slide groove (111), and the temperature monitoring device (300) further comprises a pull-out plate (320) fixedly engaged with the outer groove wall of the limiting slide groove (111), and a connecting rod (330) connected between the infrared imager (310) and the pull-out plate (320).