A class of compounds capable of being used for antibacterial textiles, and preparation method and use thereof

Abstract

The present invention provides a class of compounds that can be used for textile antibacterial treatment, as well as their preparation methods and uses, and belongs to the field of medical material technology. The present invention develops a compound with high photosensitivity, the structure of which is shown in Formula I. The compound has advantages such as good modifiability, good biocompatibility, strong bioadhesion and adsorption capacity, and easy binding to cell membranes. It can effectively adsorb nucleic acids or proteins of bacteria or viruses, and can effectively fight bacteria without light treatment. After light treatment, it has a better antibacterial effect and shows excellent antibacterial effect against both Gram-positive and Gram-negative bacteria. Textiles treated with the compound of the present invention have a certain hydrophobicity, can inhibit bacterial adhesion, exert excellent antibacterial effects, are simple to operate, low cost, and are suitable for antibacterial treatment of various textiles, with broad application prospects.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical materials, and in particular relates to a compound that can be used for antibacterial textiles, a preparation method thereof and uses thereof. Background Art

[0002] The close contact between textile materials and skin provides a base for microorganisms to transfer from human skin to textiles. Similarly, external microorganisms can transfer to the skin surface by adhering to the surface of textile materials, causing skin inflammation, infection, or allergic reactions. In addition, the growth of microorganisms on textiles can damage the textile fiber structure or dyes, resulting in a decrease in the textile's strength, color fastness, or appearance. Microorganisms can also decompose sweat, oil, or other organic matter on textiles, producing unpleasant odors. Therefore, the antimicrobial properties of textile materials have attracted widespread attention. In practical applications, textile materials are easily wetted by water, providing a breeding ground for bacteria. Dyeing with hydrophobic dyes can generally inhibit bacterial growth and adhesion on textile materials, but it does not effectively kill bacteria.

[0003] Since the advent of penicillin, antibiotics have been considered the golden rule for the clinical prevention and treatment of bacterial infections. However, with the increasing overuse of antibiotics, the problem of bacterial resistance in clinical practice is becoming increasingly serious, particularly the emergence and spread of superbugs, which render antibiotic treatment ineffective. Despite significant efforts to combat bacterial resistance, a significant gap remains between the continued emergence of resistant bacteria and the development of new antibiotics. Therefore, there is an urgent need to develop novel antimicrobial agents to inactivate bacteria and curb the growth of multidrug-resistant bacteria.

[0004] Antibacterial photodynamic therapy (APDT) is a new antibacterial treatment method that utilizes the principle of photodynamic therapy. Under the irradiation of laser light of a specific wavelength, the photosensitizer is excited, and the excited photosensitizer transfers energy to the surrounding oxygen, generating highly active reactive oxygen species (ROS) and singlet oxygen, which can then inactivate surrounding bacteria to resist bacterial infection. The reaction of APDT is mainly divided into type II and type I mechanisms. Currently, most of the existing ones are type II photodynamic systems, which are based on the reaction of triplet ground state molecular oxygen ( 3 O2) undergoes energy transfer to convert it into highly reactive singlet oxygen ( 1O2) to exert therapeutic effects. The high dependence and large consumption of oxygen by type II photosensitizers limit their efficacy against anaerobic bacteria. Unlike the energy transfer mechanism of type II, type I produces free radical ions or free radicals through electron transfer, which can effectively treat hypoxia. Different bacteria have different sensitivities to type I and type II. For example, Gram-negative bacteria are more sensitive to hydroxyl radicals, while Gram-positive bacteria are more sensitive to singlet oxygen. Currently, the bacterial lethal mechanism of APDT includes two aspects: (1) Membrane damage: Due to the large differences in the structural composition of cell walls and cell membranes, APDT is generally more effective in damaging the membrane of Gram-positive bacteria than Gram-negative bacteria. (2) DNA damage: In APDT, photosensitizers interfere with the replication and transcription process of bacteria by inhibiting DNA synthesis and binding to DNA to form complexes. In addition, the ROS generated during APDT can irreversibly damage bases and ribose, thereby destroying the DNA structure of bacteria. Combining photodynamic antimicrobial therapy with textile materials not only kills bacteria and fungi, reduces odors and stains, but also prevents their growth, keeping textiles clean and hygienic. It also isolates bacteria and viruses from the human body, preventing cross-infection. Therefore, while APDT has shown excellent efficacy against infections caused by bacteria, fungi, and viruses, particularly those caused by drug-resistant bacteria, there is still a need to develop photosensitizers with both strong type I and type II photosensitivity to achieve safe, efficient, and broad-spectrum antimicrobial effects in textile antimicrobial materials. However, few reports have yet to show textile antimicrobial materials that meet these requirements. Summary of the Invention

[0005] In view of the shortcomings of the prior art, the present invention aims to provide a class of compounds that can be used for antibacterial textiles, as well as a preparation method and use thereof.

[0006] The present invention provides a compound, the structure of which is shown in Formula I:

[0007]

[0008] Where R is C 1-15 Alkyl, X is halogen.

[0009] Furthermore, R is C 1-12 Alkyl, X is selected from chlorine, bromine, and iodine.

[0010] Further, R is -CH3, -CH2CH3, -CH2CH2CH3, -CH(CH3)CH3, -CH2(CH2)2CH3, -CH(CH3)CH2CH3, -CH2(CH2)3CH3, -CH2CH(CH3)CH2CH3, -CH2CH2CH(CH3)2, -CH2(CH2)4CH3, -CH2(CH2)2CH(CH3)2, -CH2CH2C(CH3 )3, -CH2(CH2)5CH3, -CH2(CH2)3CH(CH3)2, -CH2(CH2)2C(CH3)3, -CH2(CH2)6CH3, -CH2(CH2)4CH(CH3)2, -CH2(CH2)3C(CH3)3, -CH2(CH2)7CH3, -CH2(CH2)5CH(CH3)2, -CH2(CH2)4C(CH3)3, or -CH2(CH2) 10 CH3.

[0011] Further, it is selected from one of the following compounds:

[0012] .

[0013] The present invention also provides a method for preparing the above compound, which comprises the following steps:

[0014]

[0015] Compound 1 reacts with RY to obtain a mixture under the action of anion exchanger A, and the mixture reacts with anion exchanger B to obtain the compound; Y is a halogen;

[0016] Preferably, Y is selected from chlorine, bromine, and iodine, the anion exchanger A is potassium hexafluorophosphate, and the anion exchanger B is tetrabutylammonium chloride, tetrabutylammonium bromide, or tetrabutylammonium iodide.

[0017] Furthermore, the mass volume ratio of the compound 1 to RY is 20-60 mg:1 mL; the solvent of the reaction is an organic solvent; the temperature of the reaction is 10-90° C., and the reaction time is 5-20 hours.

[0018] Furthermore, the mass volume ratio of the compound 1 to RY is 30-50 mg:1 mL; the solvent of the reaction is methanol or N,N-dimethylformamide; the temperature of the reaction is 15-80° C., and the reaction time is 7-17 hours.

[0019] The present invention also provides an antibacterial or antiviral textile, which is a textile impregnated with the solution of the compound.

[0020] Furthermore, the dyeing method is: placing the textile into a solution of the above compound, dyeing, and drying.

[0021] Furthermore, the solvent in the solution is an organic solvent, preferably methanol; the temperature of the dipping is 10-40° C., preferably 15-35° C.; and the time is 2-7 min, preferably 5 min.

[0022] The present invention also provides use of the compound in preparing an antibacterial agent or an antiviral agent.

[0023] Furthermore, the antibacterial agent or antiviral agent is an agent applied to textiles.

[0024] Furthermore, the antibacterial agent or antiviral agent is a photosensitive antibacterial agent or antiviral agent.

[0025] Furthermore, the antibacterial agent is an agent against Gram-positive bacteria or Gram-negative bacteria, the Gram-positive bacteria is preferably Staphylococcus aureus, and the Gram-negative bacteria is preferably Escherichia coli;

[0026] The antiviral agent is an agent against herpes virus.

[0027] Definitions of terms used in the present invention: Unless otherwise specified, the initial definitions provided for groups or terms herein apply to the groups or terms throughout the specification; for terms not specifically defined in the present invention, they should be given the meanings that those skilled in the art would give them based on the disclosure and context. Among them:

[0028] The minimum and maximum carbon atom content in a hydrocarbon group is indicated by a prefix, for example, the prefix C a~b Alkyl refers to any alkyl group containing from "a" to "b" carbon atoms. For example, C 1~12 Alkyl refers to a straight or branched chain alkyl group containing 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 carbon atoms; and so on.

[0029] "Alkyl" refers to a saturated hydrocarbon chain having a specified number of member atoms. An alkyl group may be straight or branched and may be optionally substituted with one or more substituents as defined herein. Alkyl groups include methyl, ethyl, and propyl (n-propyl and isopropyl).

[0030] "Halogen" is fluorine, chlorine, bromine or iodine.

[0031] The present invention has achieved the following beneficial effects:

[0032] 1. The compounds of the present invention offer advantages such as flexible modification, good biocompatibility, strong bioadhesion and adsorption, and easy binding to cell membranes. The abundant positive charges in their structures facilitate their binding to negatively charged cell membranes or DNA, effectively adsorbing bacterial or viral nucleic acids or proteins, thereby achieving a highly effective, broad-spectrum antimicrobial effect.

[0033] 2. The compounds of the present invention are effective in antibacterial treatment even without light treatment, and exhibit even greater antibacterial effects after light treatment, demonstrating photosensitivity-enhanced antibacterial effects. Excellent antibacterial effects can be achieved under simple light conditions.

[0034] 3. The compounds of the present invention exhibit excellent antibacterial effects against both Gram-positive bacteria (such as Staphylococcus aureus) and Gram-negative bacteria (such as Escherichia coli), and have a broad-spectrum antibacterial effect.

[0035] 4. Textiles treated with the compounds of the present invention exhibit a certain hydrophobicity, which can inhibit bacterial adhesion and has excellent antibacterial properties. They are suitable for antibacterial treatment of a variety of textiles and have broad application prospects. As the length of the peripheral alkyl chains of the compounds TP-1, TP-5, and TP-12 increases, their hydrophobicity also increases. However, compared with textile samples dyed with TP-1 and TP-12, textile samples dyed with TP-5 exhibit the best antibacterial properties. This indicates that the compound TP-5, which has a specific hydrophobicity, is the most suitable antibacterial agent for application in textiles.

[0036] 5. The operation conditions for dyeing textiles with the compounds of the present invention are simple, the cost is low, and it is suitable for industrial production.

[0037] Obviously, based on the above contents of the present invention, according to common technical knowledge and customary means in this field, without departing from the above basic technical ideas of the present invention, other various forms of modifications, replacements or changes can be made.

[0038] The following is a further detailed description of the present invention through specific embodiments in the form of examples. However, this should not be construed as limiting the scope of the present invention to the following examples. All technologies implemented based on the above-mentioned content of the present invention fall within the scope of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] Figure 1 The effects of different concentrations of TP-1 on (a) Escherichia coli ( a, E.coil ) and (b) Staphylococcus aureus ( b, S. aureus ) Bacterial activity.

[0040] Figure 2The antibacterial plate graph of non-woven fabrics dyed with different concentrations of TP-1 molecules against Staphylococcus aureus.

[0041] Figure 3 The antibacterial plate diagram of non-woven fabrics dyed with different concentrations of TP-1 molecules against Escherichia coli.

[0042] Figure 4 The antibacterial plate graph of daily-use fabrics dyed with different concentrations of TP-1 molecules against Staphylococcus aureus.

[0043] Figure 5 The antibacterial plate graph of daily-use fabrics dyed with different concentrations of TP-1 molecules against Escherichia coli.

[0044] Figure 6 The antibacterial chart of non-woven fabrics dyed with different concentrations of TP-5 molecules against Staphylococcus aureus.

[0045] Figure 7 The antibacterial plate diagram of non-woven fabrics dyed with different concentrations of TP-5 molecules against Escherichia coli.

[0046] Figure 8 The antibacterial plate graph of daily-use fabrics dyed with different concentrations of TP-5 molecules against Staphylococcus aureus.

[0047] Figure 9 The antibacterial plate graph of daily-use fabrics dyed with TP-5 molecules at different concentrations against Escherichia coli.

[0048] Figure 10 The antibacterial plate graph of non-woven fabrics dyed with different concentrations of TP-12 molecules against Staphylococcus aureus.

[0049] Figure 11 The antibacterial plate diagram of non-woven fabrics dyed with different concentrations of TP-12 molecules against Escherichia coli.

[0050] Figure 12 The antibacterial plate graph of daily-use fabrics dyed with different concentrations of TP-12 molecules against Staphylococcus aureus.

[0051] Figure 13 The antibacterial plate graph of daily-use fabrics dyed with TP-12 molecules at different concentrations against Escherichia coli. DETAILED DESCRIPTION

[0052] The raw materials and equipment used in the present invention are all known products and are obtained by purchasing commercially available products.

[0053] The "normal temperature or room temperature" referred to in the present invention is 25±10°C.

[0054] The "overnight" referred to in the present invention is 12±5 hours.

[0055] The relevant reagents used in the present invention are represented as follows:

[0056] PBS: phosphate buffer (0.03 mol / L), LB: Luria-Bertani medium.

[0057] Example 1. Preparation of Compound TP-1

[0058]

[0059] Compound 1 (47.6 mg) and CH3I (1 mL) were stirred at room temperature overnight. Methanol (1 mL) was added and stirring continued overnight. The solvent was removed, and the residue was dissolved in water. A saturated aqueous solution of potassium hexafluorophosphate was added to the solution to precipitate. The precipitate was dissolved in acetonitrile, and tetrabutylammonium chloride solution was added to the acetonitrile solution to produce a sediment. The sediment was filtered and washed five times with acetonitrile. The solid was dried in a vacuum oven to obtain Compound TP-1 (35 mg, 96%) as a yellow solid. 1 H NMR (400 MHz, MeOD) δ 4.40 (s, 9H), 7.41-7.43 (d, J = 8.7 Hz, 6H), 8.08-8.11 (d, J =11.8 Hz, 6H), 8.39-8.41 (d, J = 7.1 Hz, 6H), 8.92-8.94 (d, J = 7.0 Hz, 6H).

[0060] Example 2. Preparation of Compound TP-5

[0061]

[0062] Compound 1 (30 mg), bromopentane (1 mL), and N,N-dimethylformamide (DMF) (2 mL) were mixed and stirred at 80°C overnight. The reaction solution was poured into water, and potassium hexafluorophosphate was added to the solution to precipitate. The precipitate was dissolved in acetonitrile, and an excess of tetrabutylammonium chloride solution was added to the acetonitrile solution to produce a sediment. The sediment was filtered and washed five times with acetonitrile. The sediment was then dried under vacuum to obtain Compound TP-5 (38 mg, 98%) as a yellow solid. 1 H NMR (400 MHz, MeOD) δ 0.95-0.98 (t, J = 6.9 Hz, 9H), 1.40-1.46 (m, 12H), 2.01-2.09 (m, 6H), 4.58-4.62 (t, J = 7.5 Hz, 6H), 7.41-7.43 (d,J = 8.8 Hz, 6H), 8.08-8.10 (d, J = 8.8 Hz, 6H),8.39-8.41 (d, J = 7.0 Hz, 6H), 8.92-8.94 (d, J = 6.9 Hz, 6H).

[0063] Example 3. Preparation of Compound TP-12

[0064]

[0065] A mixture of compound 1 (30 mg), bromododecane (1 mL), and DMF (2 mL) was stirred at 80°C overnight. The solvent was removed, and potassium hexafluorophosphate was added to the residue to precipitate. The precipitate was dissolved in ethyl acetate. An excess of tetrabutylammonium chloride aqueous solution was added to the ethyl acetate solution to produce a precipitate. The precipitate was filtered and dissolved in a small amount of methanol. Ethyl acetate was then added to precipitate the precipitate. This was repeated five times. The solid was dried in a vacuum oven to obtain compound TP-12 (47 mg, 99%) as a yellow solid. 1 H NMR (400 MHz, MeOD) δ0.87-0.91(t, J = 6.8 Hz, 9H), 1.44-1.24 (m,54H), 2.05 (m, 6H), 4.58-4.61(t, J = 7.5 Hz, 6H), 7.41-7.43 (d, J = 8.7 Hz, 6H),8.08-8.10 (d, J = 8.8 Hz, 6H), 8.39-8.41 (d, J = 6.9 Hz, 6H), 8.92-8.94 (d, J = 6.8 Hz, 6H).

[0066] Example 4: Preparation of antibacterial textiles

[0067] The textiles were immersed in methanol solutions of compound TP-1 with different concentrations (50 uM, 100 uM, 500 uM, and 1 mM), immersed at room temperature for 5 minutes, and then naturally dried to obtain various antibacterial textiles.

[0068] Example 5: Preparation of antibacterial textiles

[0069] The textiles were immersed in methanol solutions of compound TP-5 with different concentrations (50uM, 100uM, 500uM, and 1mM), immersed at room temperature for 5 minutes, and then naturally dried to obtain various antibacterial textiles.

[0070] Example 6: Preparation of antibacterial textiles

[0071] The textiles were immersed in methanol solutions of compound TP-12 with different concentrations (50uM, 100uM, 500uM, and 1mM), immersed at room temperature for 5 minutes, and then naturally dried to obtain antibacterial textiles.

[0072] The beneficial effects of the present invention are demonstrated by experimental examples below.

[0073] Experimental Example 1: Evaluation of the antibacterial ability of compounds as photosensitizers

[0074] 1. Experimental methods

[0075] (1) Preparation of bacterial solution

[0076] Use an inoculating loop to dip E. coli (a, E.coil ), Staphylococcus aureus (b, S. aureus ) of the bacterial culture solution (concentration of 10 5 CFU / mL; purchased from Chengdu Xinnuo Biotechnology Co., Ltd.), and then the bacteria were inoculated on solid agar plates by the plate streak method and cultured for 24 h. The single colonies on the solid agar plates were transferred to 4 mL LB liquid medium and cultured at 37°C with shaking for 18 h to obtain Escherichia coli and Staphylococcus aureus bacterial liquids.

[0077] (2) Group processing

[0078] Blank group: 2 μL of Escherichia coli or Staphylococcus aureus bacterial solution was added to 100 μL of PBS solution, incubated for 5 minutes, and then serially diluted 200 times. 100 μL was then placed on an agar plate and evenly dispersed using a spreader. After incubation for 24 hours, the cells were counted.

[0079] Control group: Pipette 100uL of compound (TP-1, TP-5, TP-12) solutions with concentrations of 2, 5, 10, 20, and 40uM into 500uL EP tubes, respectively. Then, pipette 2uL of the above bacterial solution into compound solutions of different concentrations, incubate in the dark for 5 minutes, take 100uL onto an agar plate, spread it evenly with a spreader, incubate for 24 hours, and count.

[0080] Experimental group: 100uL of the compound (TP-1, TP-5, TP-12) solutions with concentrations of 2, 5, 10, 20, and 40uM were pipetted into 500uL EP tubes, and 2uL of the above bacterial solution was pipetted into the compound solutions with different concentrations. 2 After irradiation with white light for 5 minutes, the solution was diluted 200 times with PBS, 100 μL was spread evenly on an agar plate using a spreader, and then cultured for 24 hours and counted.

[0081] The effects of different concentrations of compounds on Escherichia coli (a, E.coil ) and Staphylococcus aureus (b, S. aureus )'s antibacterial effect.

[0082] 2. Experimental results

[0083] Effects of different concentrations of compounds on Escherichia coli (a, E.coil ) and Staphylococcus aureus colony diagram Figure 1 shown.

[0084] From the experimental results, it can be seen that in the dark environment, the control group has stronger antibacterial ability as the concentration increases; in the white light environment, the experimental group has stronger antibacterial ability as the concentration increases, and under the same conditions, the light group has stronger antibacterial ability, showing a photosensitivity-enhanced antibacterial effect.

[0085] Experimental Example 2: Evaluation of the antibacterial ability of textile samples dyed with compounds

[0086] 1. Experimental methods

[0087] Cut several samples with a diameter of about 25 mm from textile samples (non-woven fabrics and daily fabrics).

[0088] Each group is processed as follows:

[0089] (1) Control group: non-woven fabrics and daily-use fabrics without any treatment.

[0090] (2) Experimental group: Non-woven fabrics and daily-use fabrics were soaked in methanol solutions of compounds (TP-1, TP-5, TP-12) at different concentrations (50 μM, 100 μM, 500 μM, 1 mM) at room temperature for 5 minutes and then naturally dried.

[0091] Prepare the sterilized lower layer of culture medium (LB medium) in an incubator at 37°C. Prepare the upper layer of culture medium: Pour 5 mL of agar medium (LB medium) onto the lower layer of culture medium. Using sterile tweezers, place the control and experimental nonwoven or household fabric samples in the center of the dish and evenly press them onto the agar until good contact is achieved between the nonwoven or household fabric and the agar.

[0092] Take 100ul of each solution with a concentration of 10 5-6 The bacterial solution (Escherichia coli, Staphylococcus aureus) with CFU / mL was evenly spread on the culture medium and cultured without light treatment or after light treatment. The light-treated sample was placed on a sterile operating table with a 2.55mW / cm 2 After 2 hours of white light exposure, the samples were placed in the incubator. Samples without light exposure were placed in the dark for 2 hours before being placed in the incubator. The inhibition zone was measured after 20 hours of incubation.

[0093] 2. Experimental results

[0094] According to the national standard GB / T 20944-2007, an inhibition zone larger than 1 mm is considered to have a good antibacterial effect. Figure 2-13 As shown, textile samples dyed with different concentrations of compounds exhibited inhibition zones of ≥1 mm against Escherichia coli and Staphylococcus aureus without white light irradiation, with inhibition zones as high as 7.5 mm. Textile samples dyed with different concentrations of compounds exhibited enhanced inhibition against Escherichia coli and Staphylococcus aureus under white light irradiation, demonstrating photosensitivity-enhanced antibacterial effects. TP-1 and TP-12 showed no significant inhibition against Escherichia coli and Staphylococcus aureus (inhibition zone: 0 mm) at a lower concentration (50 μM), while TP-5 exhibited significant inhibition against both Escherichia coli (inhibition zone: 3-7 mm) and Staphylococcus aureus (inhibition zone: 3.5-14 mm) at a concentration of 50 μM.

[0095] Compounds TP-1, TP-5, and TP-12 of the present invention exhibit increasing hydrophobicity as their peripheral alkyl chain lengths increase. However, the experimental results above revealed that textile samples dyed with TP-5 exhibited the best antibacterial properties compared to textile samples dyed with TP-1 and TP-12. This suggests that compound TP-5, possessing specific hydrophobicity, is the most suitable photosensitive antibacterial agent for use in textiles.

[0096] In summary, the present invention provides a class of compounds that can be used for textile antibacterial and its preparation method and use. The present invention has developed a compound with high photosensitivity, the structure of which is shown in Formula I. The compound has advantages such as good modifiability, good biocompatibility, strong bioadhesion and adsorption, and easy binding to cell membranes. It can effectively adsorb nucleic acids or proteins of bacteria or viruses, and can effectively fight bacteria without light treatment. After light treatment, it has better antibacterial effect, and shows excellent antibacterial effect on both Gram-positive and Gram-negative bacteria. The textiles treated with the compound of the present invention have certain hydrophobicity, can inhibit bacterial adhesion, exert excellent antibacterial effect, are simple to operate, low cost, and are suitable for antibacterial treatment of a variety of textiles, with broad application prospects.

Claims

1. A compound, characterized in that Its structure is shown in Formula I: Formula I Where R is C 1-12 Alkyl, X is chlorine.

2. The compound according to claim 1, characterized in that R is -CH3, -CH2CH3, -CH2CH2CH3, -CH(CH3)CH3, -CH2(CH2)2CH3, -CH(CH3)CH2CH3, -CH2(CH2)3CH3, -CH2CH(CH3)CH2CH3, -CH2CH2CH(CH3)2, -CH2(CH2)4CH3, -CH2(CH2)2CH(CH3)2, -CH2CH2C(CH3)3, -CH2(CH2)5CH3, -CH2(CH2)3CH(CH3)2, -CH2(CH2)2C(CH3)3, -CH2(CH2)6CH3, -CH2(CH2)4CH(CH3)2, -CH2(CH2)3C(CH3)3, -CH2(CH2)7CH3, -CH2(CH2)5CH(CH3)2, -CH2(CH2)4C(CH3)3 or -CH2(CH2) 10 CH3.

3. The compound according to claim 2, characterized in that It is selected from one of the following compounds: 。 4. A method for preparing the compound according to any one of claims 1 to 3, characterized in that: The method comprises the following steps: Compound 1 reacts with RY to obtain a mixture under the action of anion exchanger A, and the mixture reacts with anion exchanger B to obtain the compound; Y is a halogen; The anion exchanger A is potassium hexafluorophosphate, and the anion exchanger B is tetrabutylammonium chloride.

5. The method according to claim 4, characterized in that Said Y is selected from chlorine, bromine and iodine.

6. An antibacterial or antiviral textile, characterized in that: The textile is dyed with a solution of the compound according to any one of claims 1 to 3.

7. Use of the compound according to any one of claims 1 to 3 in the preparation of an antibacterial agent or an antiviral agent, wherein the antibacterial agent or antiviral agent is an agent applied to textiles.

8. The use according to claim 7, characterized in that The antibacterial agent or antiviral agent is a photosensitive antibacterial agent or antiviral agent.

9. The use according to any one of claims 7-8, characterized in that The antibacterial agent is an agent against Gram-positive bacteria or Gram-negative bacteria; The antiviral agent is an agent against herpes virus.

10. The use according to claim 9, characterized in that The Gram-positive bacteria is Staphylococcus aureus, and the Gram-negative bacteria is Escherichia coli.

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