BCL2L15 gene molecular marker for resisting porcine reproductive and respiratory syndrome and application of BCL2L15 gene molecular marker

Abstract

The invention provides a molecular marker related to porcine reproductive and respiratory syndrome resistance in a BCL2L15 gene and application of the molecular marker. The molecular marker rs331890123 is located at the 106681000th basic group of a chromosome 4 of a pig reference genome and is located in a 3 'UTR (Untranslated Region) region of the pig BCL2L15 gene. According to the invention, rs331890123 is taken as a detection site, and the polymorphism of the site obviously affects the expression of the BCL2L15 gene, so that the proliferation of the porcine reproductive and respiratory syndrome virus is inhibited. The invention also establishes a rapid detection method of the molecular marker polymorphism Tetra-primer ARMS-PCR (Reverse Transcription-Respiratory Syndrome-Polymerase Chain Reaction) related to the resistance of the porcine reproductive and respiratory syndrome. The invention provides a novel SNP molecular marker for marker-assisted selection of porcine reproductive and respiratory syndrome resistance breeding.

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