Method and device for deciding dosage of contrast agent in CT (Computed Tomography) examination

Abstract

The invention discloses a contrast agent dosage decision-making method and device in CT examination, and relates to the technical field of contrast agent usage, and the method comprises the steps: calculating the total amount of a contrast agent according to the body weight, the body fat rate, the first examination item constant, the contrast agent concentration and the tube voltage coefficient of a patient; the first examination item constant is a contrast agent reference coefficient corresponding to an examination item of a patient; calculating the flow velocity of the contrast agent according to the total amount of the contrast agent and a second examination item constant; the second inspection item constant is the contrast agent injection time of the inspection item. The accuracy of the dosage of the contrast agent is improved.

Description

Technical Field

[0001] The present application relates to the technical field of contrast agent use, and in particular to a method and device for determining the amount of contrast agent used in CT examinations. Background Art

[0002] Computed Tomography (CT) enhancement or angiography is an advanced medical imaging technique that uses contrast agents to enhance the contrast of images, allowing doctors to more clearly observe the structure of blood vessels and surrounding tissues. Among them, CT enhancement scanning technology is mainly used for more accurate observation and tissue differentiation of lesions, especially when CT plain scans cannot effectively diagnose. By injecting contrast agents, the difference between lesions and surrounding tissues can be observed more clearly, and the blood supply of lesions can be judged, thereby helping doctors make more accurate diagnoses. CT angiography (CTA) is a special examination method for blood vessels. Through three-dimensional reconstruction technology, it can show the morphology and course of blood vessels in detail, and is more helpful to observe subtle lesions in the wall and lumen, which is of great value for the diagnosis of vascular lesions. The development of CT enhancement or angiography examinations and related technologies that rely on contrast agents has brought revolutionary changes to the field of medical imaging, improved the accuracy and efficiency of diagnosis, and provided patients with better medical services.

[0003] In clinical practice, the total amount and flow rate of contrast agent are the key to the success of CT enhancement or angiography for each patient. On the one hand, when the total amount and flow rate of contrast agent are insufficient, the image after examination is indistinguishable from the CT plain scan, thus failing to achieve the purpose of examination and diagnostic requirements; on the other hand, when the total amount and flow rate of contrast agent are too large, the image will produce obvious hardening artifacts, which also fails to achieve the purpose of examination and diagnostic requirements. In addition, when the total amount and flow rate of contrast agent are fixed, the lesion detection rate of high-concentration and low-concentration contrast agents is not the same. The lesion detection rate is often better with high-concentration contrast agents than with low-concentration contrast agents, but the use of high-concentration contrast agents will increase the patient's iodine load by 23%. On the contrary, if the total amount of iodine is kept unchanged, increasing the flow rate can improve the lesion detection rate without increasing the iodine load.

[0004] Therefore, each imaging worker needs to manually calculate and use contrast agents for each patient individually. The dosage of contrast agents is crucial to ensure the safety and effectiveness of the examination. At present, the accuracy of contrast agent dosage still needs to be improved. Summary of the invention

[0005] The purpose of the present application is to provide a method and device for deciding the dosage of contrast agent in CT examination, thereby improving the accuracy of the dosage of contrast agent.

[0006] To achieve the above objectives, this application provides the following solutions:

[0007] In a first aspect, the present application provides a method for determining the dosage of contrast agent in a CT examination, comprising:

[0008] Calculate the total amount of contrast agent according to the patient's weight, body fat percentage, first examination item constant, contrast agent concentration, and tube voltage coefficient; the first examination item constant is a contrast agent reference coefficient corresponding to the patient's examination item;

[0009] The contrast agent flow rate is calculated according to the total amount of contrast agent and a second examination item constant; the second examination item constant is the contrast agent injection time of the examination item.

[0010] Optionally, the formula for calculating the total amount of contrast agent according to the patient's weight, body fat percentage, constant of the first examination item, contrast agent concentration, and tube voltage coefficient is:

[0011] Total amount of contrast medium = body weight × constant of the first examination item × contrast medium concentration × tube voltage coefficient × (1-body fat percentage).

[0012] Optionally, the formula for calculating the contrast agent flow rate according to the total amount of contrast agent and the second examination item constant is:

[0013] Contrast medium flow rate = the total amount of contrast medium / the second examination item constant.

[0014] Optionally, before calculating the total amount of contrast agent according to the patient's weight, body fat percentage, first examination item constant, contrast agent concentration, and tube voltage coefficient, the method for determining the amount of contrast agent in CT examination further includes:

[0015] The patient's body fat percentage is calculated based on the patient's body mass index. The body fat percentage calculation formula is divided into a male body fat percentage calculation formula and a female body fat percentage calculation formula;

[0016] The formula for calculating male body fat percentage is: body fat percentage = 1.20 × BMI + 0.23 × age - 16.2;

[0017] The formula for calculating female body fat percentage is: body fat percentage = 1.20 × BMI + 0.23 × age - 5.4;

[0018] BMI is body mass index.

[0019] Optionally, the examination items are divided into CT enhanced examination and CT angiography; the CT enhanced examination includes head CT enhanced scan, chest CT enhanced scan and abdominal CT enhanced scan; the CT angiography examination includes intracranial artery CTA examination, carotid artery CTA examination, thoracic and abdominal aorta CTA examination, coronary artery CTA examination, pulmonary artery CTA examination, lower limb artery CTA examination, portal vein CTV examination, mesenteric vein CTV examination and lower limb vein CTV examination.

[0020] Optionally, the contrast agent concentration includes one of the contrast agent concentrations of iodixanol, iopromide, iohexol and ioversol; the concentration of iodixanol includes 270 mgI / ml and 320 mgI / ml; the concentration of iopromide includes 300 mgI / ml; the concentrations of iohexol and ioversol both include 300 mgI / ml and 350 mgI / ml.

[0021] In a second aspect, the present application provides a device for determining the amount of contrast agent used in a CT examination, wherein the device for determining the amount of contrast agent used in a CT examination comprises:

[0022] A contrast agent total amount calculation module, used to calculate the total amount of contrast agent according to the patient's weight, body fat percentage, a first examination item constant, a contrast agent concentration, and a tube voltage coefficient; the first examination item constant is a contrast agent reference coefficient corresponding to the patient's examination item;

[0023] The contrast agent flow rate calculation module is used to calculate the contrast agent flow rate according to the total amount of contrast agent and a second examination item constant; the second examination item constant is the contrast agent injection time of the examination item.

[0024] Optionally, the device for deciding the dosage of contrast agent in CT examination further includes: a patient information entry module, and the patient information entry module is used to enter the patient's gender, age, height and weight.

[0025] Optionally, the device for deciding the dosage of contrast agent in the CT examination also includes: an examination item selection module, which is used to select examination items from CT enhanced examination and CT angiography examination, wherein the CT enhanced examination includes head CT enhanced scan, chest CT enhanced scan and abdominal CT enhanced scan; the CT angiography examination includes intracranial artery CTA examination, carotid artery CTA examination, thoracic and abdominal aorta CTA examination, coronary artery CTA examination, pulmonary artery CTA examination, lower limb artery CTA examination, portal vein CTV examination, mesenteric vein CTV examination and lower limb vein CTV examination.

[0026] Optionally, the contrast agent dosage decision device in the CT examination also includes: a contrast agent concentration selection module, which is used to select a contrast agent concentration of a contrast agent from iodixanol, iopromide, iohexol and ioversol, wherein the concentration of iodixanol includes 270mgI / ml and 320mgI / ml; the concentration of iopromide includes 300mgI / ml; the concentrations of iohexol and ioversol both include 300mgI / ml and 350mgI / ml.

[0027] According to the specific embodiments provided in this application, this application discloses the following technical effects:

[0028] The present application provides a method and device for deciding the amount of contrast agent used in a CT examination, which calculates the total amount of contrast agent based on the patient's own weight and body fat ratio (Body Fat Ratio, BFR), as well as the first examination item constant corresponding to the examination item, the contrast agent concentration, and the tube voltage coefficient, thereby achieving individualized calculation of the total amount of contrast agent and flow rate, reducing dependence on the operator's experience, and thus improving the accuracy of contrast agent dosage. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0030] Figure 1 A flowchart of a method for determining the dosage of contrast agent in a CT examination provided in one embodiment of the present application;

[0031] Figure 2 A schematic diagram of a flow chart for calculating the total amount and flow rate of contrast agent provided in one embodiment of the present application;

[0032] Figure 3 A schematic diagram of functional modules in a device for determining the dosage of contrast agent in a CT examination provided in one embodiment of the present application. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0034] In order to make the above-mentioned objects, features and advantages of the present application more obvious and easy to understand, the present application is further described in detail below with reference to the accompanying drawings and specific implementation methods.

[0035] In an exemplary embodiment, Figure 1 As shown, a method for determining the dosage of contrast agent in CT examination is provided, which is executed by a computer device, and can be executed by a computer device such as a terminal or a server alone, or by a terminal and a server together. In the embodiment of the present application, the method includes the following steps 101 to 102. Among them:

[0036] Step 101: Calculate the total amount of contrast agent according to the patient's weight, body fat percentage, first examination item constant, contrast agent concentration, and tube voltage coefficient; the first examination item constant is a contrast agent reference coefficient corresponding to the patient's examination item.

[0037] Step 102: Calculate the contrast agent flow rate according to the total amount of contrast agent and a second examination item constant; the second examination item constant is the contrast agent injection time of the examination item.

[0038] The present application calculates the total amount of contrast agent based on the patient's own weight and body fat percentage, as well as the first examination item constant, contrast agent concentration, and tube voltage coefficient corresponding to the examination item, thereby achieving individualized calculation of the total amount of contrast agent and flow rate, reducing dependence on operator experience, and thus improving the accuracy of contrast agent dosage.

[0039] The formula for calculating the total amount of contrast agent in step 101 is: total amount of contrast agent = body weight × constant of the first examination item × contrast agent concentration × tube voltage coefficient × (1-body fat percentage), such as Figure 2 shown.

[0040] The first examination item constant is the reference coefficient for the recommended use of contrast agents for different CT enhancement or angiography examination items. This parameter is based on the contrast agent dosage recommended by the guidelines and a large amount of clinical practice data analysis and verification. When performing CT enhancement scanning, choosing the appropriate tube voltage is crucial to balancing image quality and the radiation dose received by the patient. A large number of clinical studies have shown that the tube voltage KV is negatively correlated with the enhanced CT value, that is, the lower the KV, the higher the CT value. Therefore, lowering the KV can effectively reduce the amount of contrast agent used and reduce the patient's radiation dose. The tube voltage coefficient is the adjustment value relative to different tube voltages during scanning. For example, at 120KV, the tube voltage coefficient is 1. When scanning under different tube voltage conditions, the tube voltage coefficient needs to be changed accordingly.

[0041] The formula for calculating the contrast agent flow rate in step 102 is: contrast agent flow rate = the total amount of contrast agent / the second examination item constant. The second examination item constant is specifically the contrast agent injection time corresponding to different CT enhancement or angiography examination items.

[0042] In an exemplary embodiment, before calculating the total amount of contrast agent based on the patient's weight, body fat percentage, first examination item constant, contrast agent concentration, and tube voltage coefficient, the method for deciding the amount of contrast agent in CT examination also includes: calculating the patient's body fat percentage based on the patient's body mass index (Body Mass Index, BMI), and the calculation formula for body fat percentage is divided into a male body fat percentage calculation formula and a female body fat percentage calculation formula.

[0043] The formula for calculating body fat percentage for men is: body fat percentage = 1.20×BMI+0.23×age-16.2.

[0044] The formula for calculating body fat percentage for women is: body fat percentage = 1.20×BMI+0.23×age-5.4.

[0045] BMI stands for body mass index. It is a commonly used standard to measure the fatness and health of a person. Its calculation formula is weight (kg) divided by height (m) squared. The formula is: BMI = Kg / m 2 .

[0046] The amount of contrast agent used is positively correlated with body weight. The greater the body weight, the more contrast agent is used. However, the relationship between body weight and the amount of contrast agent used is not linear. Since body fat has less blood supply, the contrast agent intake is very small, which does not directly affect the metabolism and distribution of the contrast agent. In addition, the proportion of body fat content will increase with weight. Therefore, simply calculating the amount of contrast agent used by body weight will definitely exceed the actual needs of the patient, increasing the probability of adverse reactions and contrast nephropathy in the patient. Therefore, it is very necessary to calculate the patient's body fat percentage.

[0047] Body fat percentage refers to the proportion of body fat weight to total body weight, usually expressed as a percentage. Body fat percentage can more accurately reflect a person's obesity level because it directly takes into account the proportion of body fat. This application uses the BMI method to estimate body fat percentage to determine body fat percentage.

[0048] In an exemplary embodiment, the examination items are divided into CT enhanced examination and CT angiography examination; the CT enhanced examination includes head CT enhanced scan, chest CT enhanced scan and abdominal CT enhanced scan, etc.; the CT angiography examination includes intracranial artery CTA examination, carotid artery CTA examination, thoracic and abdominal aorta CTA examination, coronary artery CTA examination, pulmonary artery CTA examination, lower limb artery CTA examination, portal vein CTV examination, mesenteric vein CTV examination and lower limb vein CTV examination, etc.

[0049] This application supports the calculation of the total amount of contrast agents of various concentrations, and all types and concentrations of contrast agents currently commonly used in clinical practice are included in the calculation.

[0050] In an exemplary embodiment, the contrast agent concentration includes one of the contrast agent concentrations of iodixanol, iopromide, iohexol and ioversol; the concentration of iodixanol includes 270 mgI / ml and 320 mgI / ml; the concentration of iopromide includes 300 mgI / ml; the concentrations of iohexol and ioversol both include 300 mgI / ml and 350 mgI / ml. Currently, non-ionic contrast agents have a low incidence of toxic and side effects and high biosafety, and the use of non-ionic contrast agents is recommended.

[0051] A method for deciding the amount of contrast agent used in a CT examination also includes: summarizing and displaying the patient's basic information and the calculated body mass index and body fat percentage, simultaneously presenting the type of selected examination target and the concentration of contrast agent used, and giving recommendations to determine the contrast agent flow rate and total amount of contrast agent required for the formal scan.

[0052] The present application discloses a method for decision-making on the dosage of contrast agent in CT examination, which is an intelligent auxiliary method for decision-making on the dosage of individual contrast agent in CT enhancement or angiography examination, and aims to provide individualized decision-making support on the dosage of contrast agent for CT enhancement or angiography examination. The method can automatically calculate the most appropriate contrast dosage according to the specific situation of the patient through an intelligent algorithm to obtain high-quality image quality, while reducing the amount of contrast agent used, improving its efficiency, reducing dependence on the operator's experience, and improving the success rate of the examination.

[0053] The present application also provides an application scenario, which applies the above-mentioned method for deciding the amount of contrast agent in CT examination. Specifically: the method for deciding the amount of contrast agent in CT examination provided in this embodiment can be applied in CT enhancement or angiography examination. CT enhancement or angiography examination includes a contrast agent dosage decision link and an actual inspection link; the total amount of contrast agent is calculated according to the patient's weight, body fat percentage, first examination item constant, contrast agent concentration, and tube voltage coefficient, and the contrast agent flow rate is further calculated to enter the actual inspection link. The method for deciding the amount of contrast agent in CT examination provided in this embodiment belongs to the contrast agent dosage decision link in CT enhancement or angiography examination.

[0054] The beneficial effects of this application are mainly reflected in the following aspects:

[0055] 1. The method for deciding the dosage of contrast agent in CT examination provided in this application can fully automatically, quickly and accurately determine the dosage of contrast agent. Through factors such as the body mass index, body fat percentage, type of examination target and contrast agent concentration determined by the patient, the intelligent system can calculate personalized contrast agent dosage for the patient, minimize the dosage of contrast agent, reduce the dependence on the experience of medical personnel operating the machine, and improve the safety and effectiveness of examinations in clinical practice.

[0056] 2. This application can help optimize resource utilization and promote patient recovery: Reasonable calculation of contrast agent dosage can help reduce contrast agent waste and optimize the use of medical resources. By reducing the residual contrast agent in the body, it can help patients recover quickly and reduce discomfort after the examination and the risk of potential adverse reactions.

[0057] 3. This application can adapt to patients of different body shapes and health conditions, including children, the elderly and groups with special medical needs, meet individual needs, simplify the decision-making process of doctors and improve work efficiency.

[0058] 4. This application can calculate the dosage of contrast agent in an individualized and accurate manner, which can reduce the economic burden of patients, reduce their anxiety and fear, improve their comfort and satisfaction during the examination, improve their satisfaction with medical services, and enhance their trust in medical institutions.

[0059] Based on the same inventive concept, the embodiment of the present application also provides a device for deciding the amount of contrast agent in CT enhancement or angiography for implementing the above-mentioned method for deciding the amount of contrast agent in CT examination. The implementation scheme for solving the problem provided by the device is similar to the implementation scheme recorded in the above-mentioned method, so the specific limitations in the embodiments of one or more devices for deciding the amount of contrast agent in CT examination provided below can refer to the limitations of the method for deciding the amount of contrast agent in CT enhancement or angiography above, and will not be repeated here.

[0060] In an exemplary embodiment, Figure 3 As shown, a device for determining the dosage of contrast agent in CT examination is provided, comprising:

[0061] The total amount of contrast agent calculation module is used to calculate the total amount of contrast agent based on the patient's weight, body fat percentage, the first examination item constant, the contrast agent concentration, and the tube voltage coefficient; the first examination item constant is the contrast agent reference coefficient corresponding to the patient's examination item.

[0062] The contrast agent flow rate calculation module is used to calculate the contrast agent flow rate according to the total amount of contrast agent and a second examination item constant; the second examination item constant is the contrast agent injection time of the examination item.

[0063] The contrast agent total amount calculation module includes a contrast agent total amount calculation unit, which is used to calculate the total amount of contrast agent according to the formula: contrast agent total amount = body weight × first examination item constant × contrast agent concentration × tube voltage coefficient × (1-body fat percentage).

[0064] The contrast agent flow rate calculation module includes a contrast agent flow rate calculation unit, which is used to calculate the contrast agent flow rate according to the formula: contrast agent flow rate = the total amount of contrast agent / the second examination item constant.

[0065] The device for deciding the dosage of contrast agent in CT examination also includes: a patient information input module, and the patient information input module is used to input the patient's gender, age, height and weight.

[0066] The device for deciding the amount of contrast agent used in CT examination also includes: an examination item selection module, which is used to select examination items from CT enhanced examination and CT angiography examination. For example, if CT enhanced examination is selected, the subordinate list of examination items includes head CT enhanced scan, chest CT enhanced scan and abdominal CT enhanced scan, etc.; if CT angiography is selected, the subordinate list of examination items includes intracranial artery CTA examination, carotid artery CTA examination, thoracic and abdominal aorta CTA examination, coronary artery CTA examination, pulmonary artery CTA examination, lower limb artery CTA examination, portal vein CTV examination, mesenteric vein CTV examination and lower limb vein CTV examination, etc.

[0067] The contrast agent dosage decision device in CT examination also includes: a contrast agent concentration selection module, which is used to select a contrast agent concentration of a contrast agent from iodixanol, iopromide, iohexol and ioversol, wherein the concentration of iodixanol includes 270mgI / ml and 320mgI / ml; the concentration of iopromide includes 300mgI / ml; the concentrations of iohexol and ioversol both include 300mgI / ml and 350mgI / ml.

[0068] The device for deciding the amount of contrast agent used in CT examination also includes: a data presentation output module, which summarizes and displays the patient's basic information and the calculated body mass index and body fat percentage, simultaneously presents the type of examination target selected and the concentration of the contrast agent used, and gives suggestions to determine the contrast agent flow rate and total amount of contrast agent required for the formal scan, etc.

[0069] In an exemplary scenario 1: when a patient needs to undergo an abdominal CT enhanced scan, common clinical operations rely on experience or customary medication, such as prescribing a contrast agent iohexol 350mgI / ml*100ml*1 bottle. The present application provides a contrast agent dosage decision device in a CT examination, first inputting the patient's gender, age, height, weight and other basic information, then entering the CT enhancement or angiography examination item selection module, selecting the abdominal CT enhanced scan in the CT enhanced examination drop-down menu, and then selecting the recommended contrast agent concentration according to the patient's physical function (renal function status, whether there is diabetes, thyroid function status and whether there is an allergic constitution, etc.), after entering the information, directly entering the contrast agent total amount calculation module and the contrast agent flow rate calculation module, and instantly entering the data presentation output module, which can summarize and display the patient's basic information and the calculated body mass index and body fat rate, synchronously present the type of selected examination target and the concentration of the contrast agent used, and give suggestions to determine the contrast agent flow rate and contrast agent dosage required for the formal scan. For example, the patient is a male, 40 years old, 1.75m tall, 60Kg in weight, denies abnormal renal function, diabetes, abnormal thyroid function, and allergic history, and chooses iohexol 350mgI / ml and tube voltage 120KV. Before using the contrast agent dosage decision device in the CT examination of this application, the patient calculated that the contrast agent dosage was 78.86ml, the high-pressure syringe injection rate of the contrast agent was 2.8ml / s, and the injection time was 28s; after using the contrast agent dosage decision device in the CT examination of this application, it is recommended to use 65.84ml of contrast agent, the high-pressure syringe injection rate of the contrast agent is 2.35ml / s, and the injection time is 28s. If the patient is male, 40 years old, 1.60m tall, 160Kg in weight, denies abnormal renal function, diabetes, abnormal thyroid function, allergy history, etc., and also selects iohexol 350mgI / ml and tube voltage 120KV, the patient calculates the contrast agent dosage as 210.29ml before using the contrast agent dosage decision device in the CT examination of the present application, the contrast agent injection rate of the high-pressure syringe is 7.5ml / s, and the injection time is 28s; after using the contrast agent dosage decision device in the CT examination of the present application, it is recommended to use 67.29ml of contrast agent, the contrast agent injection rate of the high-pressure syringe is 2.4ml / s, and the injection time is 28s. A simple comparison shows that the difference in the amount of contrast agent before and after using the contrast agent dosage decision device in the CT examination of the present application is very large, especially for patients with large body weight.

[0070] In an exemplary scenario 2: when a patient needs to undergo a coronary CTA scan, common clinical operations rely on experience or customary medication, such as prescribing a contrast agent ioversol 300mgI / ml*100ml dosage*1 bottle. The present application provides a contrast agent dosage decision device for CT examination, firstly inputting the patient's gender, age, height, weight and other basic information, then entering the CT enhancement or angiography examination item selection unit, selecting the coronary CTA scan in the CT angiography examination drop-down menu, and then selecting the recommended contrast agent concentration according to the patient's physical function (renal function status, whether there is diabetes, thyroid function status and whether there is an allergic constitution, etc.), after the information is entered, directly entering the contrast agent total amount calculation module and the contrast agent flow rate calculation module, and instantly entering the data presentation output module, which can summarize and display the patient's basic information and the calculated body mass index and body fat rate, synchronously presenting the type of selected examination target and the concentration of the contrast agent used, and giving suggestions to determine the contrast agent flow rate and contrast agent dosage required for the formal scan. For example, a female patient is 60 years old, 1.60m tall, and weighs 60kg. She denies abnormal renal function, diabetes, abnormal thyroid function, and a history of allergies. She chooses ioversel 300mgI / ml and a tube voltage of 100KV. Before using the device for deciding the dosage of contrast agent in a CT examination of the present application, the patient calculated that the dosage of contrast agent was 73.69ml, the injection rate of contrast agent by the high-pressure syringe was 2.6ml / s, and the injection time was 28s. After using the device for deciding the dosage of contrast agent in a CT examination of the present application, it is recommended to use 51.48ml of contrast agent, the injection rate of contrast agent by the high-pressure syringe was 1.84ml / s, and the injection time was 28s. If the patient is female, 60 years old, 1.50m tall, 80Kg in weight, denies abnormal renal function, diabetes, abnormal thyroid function, allergic history, etc., and also chooses ioversel 300mgI / ml and tube voltage 100KV, the patient calculates the contrast agent dosage as 98.26ml before using the contrast agent dosage decision device in CT examination of the present application, the contrast agent injection rate of the high-pressure syringe is 3.5ml / s, and the injection time is 28s; after using the contrast agent dosage decision device in CT examination of the present application, it is recommended to use 44.37ml of contrast agent, the contrast agent injection rate of the high-pressure syringe is 1.58ml / s, and the injection time is 28s. In addition to individual differences, it is not difficult to find that the differences in the purpose of the examination and the differences in the use of contrast agents are also very large.

[0071] After accurate individual calculation of the contrast agent dosage, it was found that the use of contrast agents varies greatly due to individual differences and different examination purposes. Irrational use of contrast agents will bring some problems: on the one hand, if the dosage is too large, the contrast agent will be wasted, and it will increase the economic and physical burden of the patient, may increase the risk of potential adverse reactions, and cause a series of waste of medical resources; on the other hand, if the dosage is too small, it may lead to a decline in image quality, which not only affects the accuracy of diagnosis, but may also require repeated imaging examinations, which will increase the radiation dose received by the patient, the total dose of contrast agents is excessive, and it also increases medical costs and resource consumption.

[0072] By applying the contrast agent dosage decision device in CT examination of the present application through the above-mentioned embodiment, it can effectively ensure that the patient is provided with individualized contrast agent dosage decision support. The device can automatically calculate the most appropriate contrast agent dosage according to the specific situation of the patient to obtain high-quality image quality, while reducing the amount of contrast agent used, improving its use efficiency, reducing dependence on the operator's experience, improving the success rate of the examination, and facilitating the clinical formulation of safer and more scientific examination and treatment plans.

[0073] The technical features of the above embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0074] This article uses specific examples to illustrate the principles and implementation methods of this application. The description of the above embodiments is only used to help understand the method and core ideas of this application. At the same time, for those skilled in the art, according to the ideas of this application, there will be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as limiting this application.

Claims

1. A method for determining the dosage of contrast agent in CT examination, characterized in that: The method for determining the amount of contrast agent used in the CT examination includes: Calculate the total amount of contrast agent according to the patient's weight, body fat percentage, first examination item constant, contrast agent concentration, and tube voltage coefficient; the first examination item constant is a contrast agent reference coefficient corresponding to the patient's examination item; The contrast agent flow rate is calculated according to the total amount of contrast agent and a second examination item constant; the second examination item constant is the contrast agent injection time of the examination item.

2. The method for determining the amount of contrast agent used in CT examination according to claim 1, characterized in that: The formula for calculating the total amount of contrast agent based on the patient's weight, body fat percentage, constant of the first examination item, contrast agent concentration, and tube voltage coefficient is: Total amount of contrast medium = body weight × constant of the first examination item × contrast medium concentration × tube voltage coefficient × (1-body fat percentage).

3. The method for determining the amount of contrast agent used in CT examination according to claim 1, characterized in that: The formula for calculating the contrast agent flow rate according to the total amount of contrast agent and the second examination item constant is: Contrast medium flow rate = the total amount of contrast medium / the second examination item constant.

4. The method for determining the amount of contrast agent used in CT examination according to claim 1, characterized in that: Before calculating the total amount of contrast agent according to the patient's weight, body fat percentage, constant of the first examination item, contrast agent concentration, and tube voltage coefficient, the method for determining the amount of contrast agent in CT examination further includes: The patient's body fat percentage is calculated based on the patient's body mass index. The body fat percentage calculation formula is divided into a male body fat percentage calculation formula and a female body fat percentage calculation formula; The formula for calculating male body fat percentage is: body fat percentage = 1.20 × BMI + 0.23 × age - 16.2; The formula for calculating female body fat percentage is: body fat percentage = 1.20 × BMI + 0.23 × age - 5.4; BMI is body mass index.

5. The method for determining the amount of contrast agent used in CT examination according to claim 1, characterized in that: The examination items are divided into CT enhanced examination and CT angiography; the CT enhanced examination includes head CT enhanced scan, chest CT enhanced scan and abdominal CT enhanced scan; the CT angiography includes intracranial artery CTA examination, carotid artery CTA examination, thoracic and abdominal aorta CTA examination, coronary artery CTA examination, pulmonary artery CTA examination, lower limb artery CTA examination, portal vein CTV examination, mesenteric vein CTV examination and lower limb vein CTV examination.

6. The method for determining the amount of contrast agent used in CT examination according to claim 1, characterized in that: The contrast agent concentration includes one of the contrast agent concentrations of iodixanol, iopromide, iohexol and ioversol; the concentration of iodixanol includes 270 mgI / ml and 320 mgI / ml; the concentration of iopromide includes 300 mgI / ml; the concentrations of iohexol and ioversol both include 300 mgI / ml and 350 mgI / ml.

7. A device for determining the dosage of contrast agent in CT examination, characterized in that: The contrast agent dosage decision device in the CT examination comprises: A contrast agent total amount calculation module, used to calculate the total amount of contrast agent according to the patient's weight, body fat percentage, a first examination item constant, a contrast agent concentration, and a tube voltage coefficient; the first examination item constant is a contrast agent reference coefficient corresponding to the patient's examination item; The contrast agent flow rate calculation module is used to calculate the contrast agent flow rate according to the total amount of contrast agent and a second examination item constant; the second examination item constant is the contrast agent injection time of the examination item.

8. The device for determining the dosage of contrast agent in CT examination according to claim 7, characterized in that: The device for deciding the dosage of contrast agent in CT examination also includes: a patient information input module, and the patient information input module is used to input the patient's gender, age, height and weight.

9. The device for determining the dosage of contrast agent in CT examination according to claim 7, characterized in that: The device for deciding the amount of contrast agent used in CT examination also includes: an examination item selection module, which is used to select examination items from CT enhanced examination and CT angiography examination, wherein the CT enhanced examination includes head CT enhanced scan, chest CT enhanced scan and abdominal CT enhanced scan; the CT angiography examination includes intracranial artery CTA examination, carotid artery CTA examination, thoracic and abdominal aorta CTA examination, coronary artery CTA examination, pulmonary artery CTA examination, lower limb artery CTA examination, portal vein CTV examination, mesenteric vein CTV examination and lower limb vein CTV examination.

10. The device for determining the dosage of contrast agent in CT examination according to claim 7, characterized in that: The contrast agent dosage decision device in CT examination also includes: a contrast agent concentration selection module, which is used to select a contrast agent concentration of a contrast agent from iodixanol, iopromide, iohexol and ioversol, wherein the concentration of iodixanol includes 270mgI / ml and 320mgI / ml; the concentration of iopromide includes 300mgI / ml; the concentrations of iohexol and ioversol both include 300mgI / ml and 350mgI / ml.

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