Skin cell barrier repair cosmetic composition and preparation method thereof

Abstract

The invention discloses a skin cell barrier repairing cosmetic composition. The invention relates to an anti-allergy mask which is prepared from the following raw materials in parts by weight: 10-30 parts of ceramide, 1-50 parts of polypeptide, 20-40 parts of tetrahydromethylpyrimidine carboxylic acid, 50-80 parts of collagen III, 1-30 parts of a pepper stem extract, 3-30 parts of a parthenocissus parvifolia extract, 1-30 parts of an olive leaf extract, 8-45 parts of an inonotus obliquus extract, 6-32 parts of a achillea millefolium extract and 1-25 parts of hyaluronic acid. 10 to 22 parts of squalane and 20 to 30 parts of xanthan gum. The neuro-curamine-multi-skin skin repairing agent with a net structure is prepared from neuro-curamine and multi-skin, can form a protective film on the skin surface during use, prolongs the skin protection time, plays a skin barrier role, serves as an excellent skin cell repairing means, and has a good skin repairing effect. The composition is suitable for occasions of repairing, maintaining and improving human skin.

Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetic manufacturing, and specifically relates to a skin cell barrier repair cosmetic composition and a preparation method thereof. Background Art

[0002] With the development of modern society, people's life pressure is constantly increasing, living habits are irregular, and the influence of environmental, climatic and other factors makes it inevitable that the skin will be harmed and damaged in daily life. Therefore, repairing, maintaining and improving the skin has become one of the most important issues for modern people. Some skin repair products have been put on the market, but due to differences in product ingredients, quality and other factors, the efficacy and safety of the products are uneven, and they cannot play a role in skin repair. In this regard, we propose a skin cell barrier repair cosmetic composition and a preparation method thereof. Summary of the invention

[0003] In view of the deficiencies of the prior art, the present invention provides a skin cell barrier repair cosmetic composition and a preparation method thereof, which solves the problem of being unable to repair the skin.

[0004] To achieve the above objectives, the present invention provides the following technical solution: a skin cell barrier repair cosmetic composition, prepared from the following raw materials in parts by weight: 10-30 parts of ceramide, 1-50 parts of polypeptide, 20-40 parts of tetrahydromethylpyrimidine carboxylic acid, 50-80 parts of type III collagen, 1-30 parts of kava stem extract, 3-30 parts of feverfew extract, 1-30 parts of olive leaf extract, 8-45 parts of inonotus obliquus extract, 6-32 parts of yarrow extract, 1-25 parts of hyaluronic acid, 10-22 parts of squalane and 20-30 parts of xanthan gum.

[0005] Preferably, the polypeptide is an intermediate product of protein hydrolysis, and the polypeptide is composed of three or more amino acid molecules.

[0006] Preferably, the type III collagen is composed of a homotrimer or three identical peptide chains.

[0007] Preferably, the kava stem extract is extracted from the rhizome of Piper methysticum, and the kava stem extract contains 30%-70% kavalactones.

[0008] Preferably, the feverfew extract is an extract from feverfew buds, and the main component of the feverfew extract is parthenolide.

[0009] Preferably, the olive leaf extract is a substance extracted from olive tree leaves, and the main component of the olive leaf extract is oleuropein.

[0010] Preferably, the Inonotus obliquus extract is made from the fruiting body of Inonotus obliquus, and the Yarrow extract is a powdery substance extracted from Yarrow.

[0011] Preferably, the squalane is extracted from shark liver, and the guar gum is used to increase viscosity.

[0012] A method for preparing a skin cell barrier repair cosmetic composition, the preparation steps comprising:

[0013] S1: Prepare the following raw materials in parts by weight: 10-30 parts of ceramide, 1-50 parts of polypeptide, 20-40 parts of ectoine, 50-80 parts of type III collagen, 1-30 parts of kava stem extract, 3-30 parts of feverfew extract, 1-30 parts of olive leaf extract, 8-45 parts of inonotus birch extract, 6-32 parts of yarrow extract, 1-25 parts of hyaluronic acid, 10-22 parts of squalane, 20-30 parts of xanthan gum and 300-800 parts of hot water;

[0014] S2: Pour yarrow extract, type III collagen, kava stem extract, feverfew extract, olive leaf extract, inonotus birch extract and squalane into a reaction kettle for stirring, and pour in a proportion of hot water to dissolve and mix during the stirring process;

[0015] S3: After the materials in S2 are stirred, they are taken out in time and filtered through a filtering device to obtain a mixture A;

[0016] S4: pouring ceramide, polypeptide, ectoine and hyaluronic acid into a reaction kettle for heating and stirring, pouring the obtained mixture A into the reaction kettle for stirring and mixing, obtaining a mixture B, and filtering the mixture;

[0017] S5: pouring the mixture B filtered in the above S4 into a sterilization device for sterilization, and performing multiple centrifugation to remove bacteria and impurities;

[0018] S6: Pour the mixture B into an emulsifying pot for emulsification. During the process, pour xanthan gum to increase the viscosity. Take out and place in a dryer for drying. Collect by centralized filtration to obtain a repairing lotion.

[0019] Preferably, the filtering device is a continuous pressure filter, the pore size of the filter is 15 microns, and the sterilizing device is an autoclave.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] The present invention prepares the ceramide-polypeptide skin repair agent with a network structure by combining ceramide and polypeptide. When used, the ceramide-polypeptide skin repair agent can form a protective film on the skin surface, prolong the protection time of the skin, and play a role as a skin barrier. As an excellent means of repairing skin cells, it is suitable for occasions of human skin repair, maintenance and improvement. DETAILED DESCRIPTION

[0022] Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without making any creative work shall fall within the scope of protection of the present invention.

[0023] Example 1

[0024] A method for preparing a skin cell barrier repair cosmetic composition, the preparation steps comprising:

[0025] S1: Prepare the following raw materials in parts by weight: 10 parts of ceramide, 3 parts of polypeptide, 22 parts of ectoine, 52 parts of type III collagen, 18 parts of kava stem extract, 10 parts of feverfew extract, 11 parts of olive leaf extract, 40 parts of inonotus birch extract, 15 parts of yarrow extract, 20 parts of hyaluronic acid, 15 parts of squalane, 22 parts of xanthan gum and 300 parts of hot water;

[0026] S2: Pour yarrow extract, type III collagen, kava stem extract, feverfew extract, olive leaf extract, inonotus birch extract and squalane into a reaction kettle for stirring, and pour in a proportion of hot water to dissolve and mix during the stirring process;

[0027] S3: After the materials in S2 are stirred, they are taken out in time and filtered through a filtering device to obtain a mixture A;

[0028] S4: pouring ceramide, polypeptide, ectoine and hyaluronic acid into a reaction kettle for heating and stirring, pouring the obtained mixture A into the reaction kettle for stirring and mixing, obtaining a mixture B, and filtering the mixture;

[0029] S5: pouring the mixture B filtered in the above S4 into a sterilization device for sterilization, and performing multiple centrifugation to remove bacteria and impurities;

[0030] S6: Pour the mixture B into an emulsifying pot for emulsification. During the process, pour xanthan gum to increase the viscosity. Take out and place in a dryer for drying. Collect by centralized filtration to obtain a repairing lotion.

[0031] Example 2

[0032] A method for preparing a skin cell barrier repair cosmetic composition, the preparation steps comprising:

[0033] S1: Prepare the following raw materials in parts by weight: 22 parts of ceramide, 45 parts of polypeptide, 33 parts of ectoine, 65 parts of type III collagen, 23 parts of kava stem extract, 14 parts of feverfew extract, 13 parts of olive leaf extract, 33 parts of inonotus birch extract, 16 parts of yarrow extract, 19 parts of hyaluronic acid, 19 parts of squalane, 21 parts of xanthan gum and 800 parts of hot water;

[0034] S2: Pour yarrow extract, type III collagen, kava stem extract, feverfew extract, olive leaf extract, inonotus birch extract and squalane into a reaction kettle for stirring, and pour in a proportion of hot water to dissolve and mix during the stirring process;

[0035] S3: After the materials in S2 are stirred, they are taken out in time and filtered through a filtering device to obtain a mixture A;

[0036] S4: pouring ceramide, polypeptide, ectoine and hyaluronic acid into a reaction kettle for heating and stirring, pouring the obtained mixture A into the reaction kettle for stirring and mixing, obtaining a mixture B, and filtering the mixture;

[0037] S5: pouring the mixture B filtered in the above S4 into a sterilization device for sterilization, and performing multiple centrifugation to remove bacteria and impurities;

[0038] S6: Pour the mixture B into an emulsifying pot for emulsification. During the process, pour xanthan gum to increase the viscosity. Take out and place in a dryer for drying. Collect by centralized filtration to obtain a repairing lotion.

[0039] Example 3

[0040] A method for preparing a skin cell barrier repair cosmetic composition, the preparation steps comprising:

[0041] S1: Prepare the following raw materials in parts by weight: 23 parts of ceramide, 26 parts of polypeptide, 33 parts of ectoine, 67 parts of type III collagen, 21 parts of kava stem extract, 12 parts of feverfew extract, 11 parts of olive leaf extract, 28 parts of inonotus obliquus extract, 31 parts of yarrow extract, 23 parts of hyaluronic acid, 17 parts of squalane, 23 parts of xanthan gum and 750 parts of hot water;

[0042] S2: Pour yarrow extract, type III collagen, kava stem extract, feverfew extract, olive leaf extract, inonotus birch extract and squalane into a reaction kettle for stirring, and pour in a proportion of hot water to dissolve and mix during the stirring process;

[0043] S3: After the materials in S2 are stirred, they are taken out in time and filtered through a filtering device to obtain a mixture A;

[0044] S4: pouring ceramide, polypeptide, ectoine and hyaluronic acid into a reaction kettle for heating and stirring, pouring the obtained mixture A into the reaction kettle for stirring and mixing, obtaining a mixture B, and filtering the mixture;

[0045] S5: pouring the mixture B filtered in the above S4 into a sterilization device for sterilization, and performing multiple centrifugation to remove bacteria and impurities;

[0046] S6: Pour the mixture B into an emulsifying pot for emulsification. During the process, pour xanthan gum to increase the viscosity. Take out and place in a dryer for drying. Collect by centralized filtration to obtain a repairing lotion.

[0047] Example 4

[0048] A method for preparing a skin cell barrier repair cosmetic composition, the preparation steps comprising:

[0049] S1: Prepare the following raw materials in parts by weight: 21 parts of ceramide, 36 parts of polypeptide, 37 parts of ectoine, 69 parts of type III collagen, 28 parts of kava stem extract, 14 parts of feverfew extract, 22 parts of olive leaf extract, 11 parts of inonotus birch extract, 13 parts of yarrow extract, 21 parts of hyaluronic acid, 22 parts of squalane, 21 parts of xanthan gum and 500 parts of hot water;

[0050] S2: Pour yarrow extract, type III collagen, kava stem extract, feverfew extract, olive leaf extract, inonotus birch extract and squalane into a reaction kettle for stirring, and pour in a proportion of hot water to dissolve and mix during the stirring process;

[0051] S3: After the materials in S2 are stirred, they are taken out in time and filtered through a filtering device to obtain a mixture A;

[0052] S4: pouring ceramide, polypeptide, ectoine and hyaluronic acid into a reaction kettle for heating and stirring, pouring the obtained mixture A into the reaction kettle for stirring and mixing, obtaining a mixture B, and filtering the mixture;

[0053] S5: pouring the mixture B filtered in the above S4 into a sterilization device for sterilization, and performing multiple centrifugation to remove bacteria and impurities;

[0054] S6: Pour the mixture B into an emulsifying pot for emulsification. During the process, pour xanthan gum to increase the viscosity. Take out and place in a dryer for drying. Collect by centralized filtration to obtain a repairing lotion.

[0055] Example 5

[0056] A method for preparing a skin cell barrier repair cosmetic composition, the preparation steps comprising:

[0057] S1: Prepare the following raw materials in parts by weight: 30 parts of ceramide, 31 parts of polypeptide, 21 parts of ectoine, 65 parts of type III collagen, 22 parts of kava stem extract, 12 parts of feverfew extract, 1 part of olive leaf extract, 8 parts of inonotus birch extract, 12 parts of yarrow extract, 20 parts of hyaluronic acid, 20 parts of squalane, 20 parts of xanthan gum and 700 parts of hot water;

[0058] S2: Pour yarrow extract, type III collagen, kava stem extract, feverfew extract, olive leaf extract, inonotus birch extract and squalane into a reaction kettle for stirring, and pour in a proportion of hot water to dissolve and mix during the stirring process;

[0059] S3: After the materials in S2 are stirred, they are taken out in time and filtered through a filtering device to obtain a mixture A;

[0060] S4: pouring ceramide, polypeptide, ectoine and hyaluronic acid into a reaction kettle for heating and stirring, pouring the obtained mixture A into the reaction kettle for stirring and mixing, obtaining a mixture B, and filtering the mixture;

[0061] S5: pouring the mixture B filtered in the above S4 into a sterilization device for sterilization, and performing multiple centrifugation to remove bacteria and impurities;

[0062] S6: Pour the mixture B into an emulsifying pot for emulsification. During the process, pour xanthan gum to increase the viscosity. Take out and place in a dryer for drying. Collect by centralized filtration to obtain a repairing lotion.

[0063] Peptides mainly control the growth, development, immune regulation and metabolism of the human body. They are in a state of balance in the human body and can regulate the physiological functions of the human body and enhance and exert the physiological activities of the human body.

[0064] Type III collagen can reduce wrinkles, promote cell generation, and has strong elasticity or repair functions;

[0065] The kava stem extract has antispasmodic, anti-epileptic, local anesthetic, anti-inflammatory, antiseptic and antifungal effects. The preparation method is as follows: the kava stem is crushed, dynamically extracted with ethanol, the extract is sucked into a vacuum concentration container to obtain a filtrate, and the filtrate is concentrated to a viscosity of more than 25 bom. After adding a dispersant to a stirrer, the extract is fully and slowly stirred while stirring, and the kava stem extract is sieved through a 60-mesh screen to obtain the kava stem extract.

[0066] Feverfew extract has strong anti-tumor activity and is a brown-yellow powder;

[0067] Olive leaf extract has immunomodulatory and antioxidant effects;

[0068] Inonotus obliquus extract has anti-cancer and anti-aging effects and is a brown powdery substance;

[0069] Yarrow extract has the function of restoring the elasticity and balance of skin fiber tissue and accelerating the metabolism of skin cells;

[0070] Ceramide can significantly enhance the adhesion between keratinized cells, improve skin dryness, and reduce skin desquamation;

[0071] Hyaluronic acid can protect the skin to a certain extent and make the skin elastic;

[0072] Squalane can strengthen and repair the outer surface of the skin and form a protective film. It is prepared by extraction and then refining.

[0073] The following table shows the test results of the repair lotion in this embodiment.

[0074]

[0075]

[0076] Result analysis: From the test results in the above table, it can be seen that the repairing lotion prepared in Example 2 has the best effect. The test days are all 5 days. Within 5 days, the water content in the repairing lotion is 30%, the colony count is 11%, and the product will not cause irritation to the skin.

[0077] Colony experiment

[0078] S1: Mark a 2×2 cm2 test area on the skin and mark multiple areas for control;

[0079] S2: Use a cotton swab to dip a small amount of saline solution in each area and wipe it back and forth to sterilize and disinfect.

[0080] S3: Soak the cotton swab to obtain the total number of bacteria, and this sample is used as the initial colony count of the skin, recorded as A;

[0081] S4: Then apply the sample in the embodiment to the experimental area;

[0082] S5: Observe for 6 hours and wipe again with a cotton swab;

[0083] S6: Get the colony count B, and calculate the total number of bacteria.

[0084] Recovery rate of skin colonies = [BA] x 100%.

[0085] Water content experiment

[0086] S1: Select a stable environment with constant temperature and humidity;

[0087] S2: The forearm of the experimenter was selected for the experiment, and the blank control group and product application group areas were divided, and a 2cm×2cm mark was made on the corresponding test area;

[0088] S3: Use a skin moisture meter to measure the water content of the designated area six times in parallel, and take the average value as the initial value of the water content;

[0089] S4: Wait for 10 hours and test the samples in the area again. Take six samples, take the average value, and calculate the moisture content.

[0090] The viscosity of the emulsion is measured as follows:

[0091] S1: Prepare the following measuring instruments: stirring rod, conical flask, viscometer and water bath;

[0092] S2: Weigh the sample, dry it, and place it in a conical flask;

[0093] S3: Add an appropriate amount of water to the conical flask and shake it evenly, and continue to add an appropriate amount of water and shake it;

[0094] S4: Place the conical flask in a water bath, pour 20-degree water into the water bath, stir with a stirring rod, put in a viscometer for measurement, and take the rotor for measurement for 10 minutes.

[0095] The calculation formula is b1 = j * H

[0096] b1 = sample viscosity;

[0097] j = viscometer reading value;

[0098] H = rotor constant.

[0099]

[0100] According to the GB / T35828-2018 risk substance testing method, the skin barrier moisturizing repair cream was tested for risk substance content. The principle of the test is: after the sample is digested, the sample is measured by an inductively coupled plasma mass spectrometer, which consists of an ion source and a mass spectrometer. After atomization, the sample solution is sent into the ICP torch through the carrier gas, and is converted into positively charged ions after evaporation, dissociation, atomization, ionization and other processes. After ion focusing, it enters the mass spectrometer, where it is separated and collected. For a certain mass-to-charge ratio, it is proportional to the number of ions entering the mass spectrometer, that is, the mass spectrometer signal intensity is proportional to the element to be measured. Compared with the standard series, it is quantitative, and the content can be measured.

[0101] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0102] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A skin cell barrier repair cosmetic composition, characterized in that: The invention is prepared from the following raw materials in parts by weight: 10-30 parts of ceramide, 1-50 parts of polypeptide, 20-40 parts of tetrahydromethylpyrimidine carboxylic acid, 50-80 parts of type III collagen, 1-30 parts of kava stem extract, 3-30 parts of feverfew extract, 1-30 parts of olive leaf extract, 8-45 parts of inonotus obliquus extract, 6-32 parts of yarrow extract, 1-25 parts of hyaluronic acid, 10-22 parts of squalane and 20-30 parts of xanthan gum.

2. The skin cell barrier repair cosmetic composition according to claim 1, characterized in that: The polypeptide is an intermediate product of protein hydrolysis, and the polypeptide is composed of three or more amino acid molecules.

3. The skin cell barrier repair cosmetic composition according to claim 1, characterized in that: The type III collagen is composed of a homotrimer or three identical peptide chains.

4. The skin cell barrier repair cosmetic composition according to claim 1, characterized in that: The kava stem extract is an item extracted from the rhizome of kava as a raw material, and the kava stem extract contains 30%-70% of kavalactones.

5. The skin cell barrier repair cosmetic composition according to claim 1, characterized in that: The feverfew extract is an extract from feverfew buds, and the main component of the feverfew extract is parthenolide.

6. The skin cell barrier repair cosmetic composition according to claim 1, characterized in that: The olive leaf extract is a substance extracted from olive tree leaves, and the main component of the olive leaf extract is oleuropein.

7. The skin cell barrier repair cosmetic composition according to claim 1, characterized in that: The Inonotus obliquus extract is made from the fruiting body of Inonotus obliquus, and the Yarrow extract is a powdery substance extracted from Yarrow.

8. The skin cell barrier repair cosmetic composition according to claim 1, characterized in that: The squalane is extracted from shark liver, and the guar gum is used to increase viscosity.

9. A method for preparing a skin cell barrier repair cosmetic composition, characterized in that: The preparation steps include: S1: Prepare the following raw materials in parts by weight: 10-30 parts of ceramide, 1-50 parts of polypeptide, 20-40 parts of ectoine, 50-80 parts of type III collagen, 1-30 parts of kava stem extract, 3-30 parts of feverfew extract, 1-30 parts of olive leaf extract, 8-45 parts of inonotus birch extract, 6-32 parts of yarrow extract, 1-25 parts of hyaluronic acid, 10-22 parts of squalane, 20-30 parts of xanthan gum and 300-800 parts of hot water; S2: Pour yarrow extract, type III collagen, kava stem extract, feverfew extract, olive leaf extract, inonotus birch extract and squalane into a reaction kettle for stirring, and pour in a proportion of hot water to dissolve and mix during the stirring process; S3: After the materials in S2 are stirred, they are taken out in time and filtered through a filtering device to obtain a mixture A; S4: pouring ceramide, polypeptide, ectoine and hyaluronic acid into a reaction kettle for heating and stirring, pouring the obtained mixture A into the reaction kettle for stirring and mixing, obtaining a mixture B, and filtering the mixture; S5: pouring the mixture B filtered in the above S4 into a sterilization device for sterilization, and performing multiple centrifugation to remove bacteria and impurities; S6: Pour the mixture B into an emulsifying pot for emulsification. During the process, pour xanthan gum to increase the viscosity. Take out and place in a dryer for drying. Collect by centralized filtration to obtain a repairing lotion.

10. The method for preparing the skin cell barrier repairing cosmetic composition according to claim 9, characterized in that: The filtering device is a continuous pressure filter, the pore size of the filter is 15 microns, and the sterilizing device is a high-pressure sterilizer.

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