Pressurizing experiment device for biodegradable sample

Abstract

The invention discloses a biodegradable sample pressurization experiment device, which not only can apply pressure to a sample in a constant-temperature water bath, but also can measure the displacement of the sample in a soaking degradation process in real time. A support is included; a counterweight frame is arranged at the top of the support, a transverse plate is arranged at the bottom of the support, the pressurizing plate is used for applying pressure to a sample, one end of the cable in the pulley block system is connected with the counterweight frame, the other end of the cable is connected with the pressurizing plate, and the sample is located between the pressurizing plate and the transverse plate. The counter weight frame applies pulling force to the cable and applies upward pulling force to the pressurizing plate after turning through a pulley block in the pulley block system so as to enable the sample to bear pressure; the lower end of the bracket is positioned in the soak solution in the beaker, so that the sample is positioned below the liquid level of the soak solution; according to the invention, pressurization, real-time measurement and fixation support can be provided for simulation of experiments of biodegradable samples in scenes of in-vivo load bearing, muscle traction and the like.

Description

Technical Field

[0001] The invention relates to the technical field of biomedical experimental equipment, in particular to a biodegradable sample pressurization experimental device. Background Art

[0002] In the prior art, in experiments simulating the degradation and deformation of degradable materials in the body, it is often necessary to apply a certain stress to the sample in order to simulate the actual situation of the sample in the body as much as possible; therefore, in addition to immersing the sample in simulated body fluid in a constant temperature water bath, it is also necessary to apply a certain pressure to the sample, and measure and record the displacement of the sample under stress in real time; however, there is currently no special experimental equipment that can apply pressure to the sample in a constant temperature water bath and measure its displacement in real time. Based on the above technical problems, the present invention provides a biodegradable sample pressurization experimental device. Summary of the invention

[0003] The purpose of the present invention is to overcome the shortcomings of the prior art, meet practical needs, and provide a biodegradable sample pressurization experimental device, which can apply pressure to the sample in a constant temperature water bath and also realize real-time measurement of its displacement.

[0004] In order to achieve the purpose of the present invention, the technical solution adopted by the present invention is: A biodegradable sample pressurization experimental device is designed, comprising a bracket; a counterweight frame is provided on the top of the bracket, a horizontal plate is provided on the bottom of the bracket, and also comprises a pressurization plate for applying pressure to the sample, and a pulley system with a cable, one end of the cable in the pulley system is connected to the counterweight frame, and the other end is connected to the pressurization plate, the sample is located between the pressurization plate and the horizontal plate, the counterweight frame applies tension to the cable and applies upward tension to the pressurization plate after turning the pulley in the pulley system, thereby pressurizing the sample; The lower end of the support is located in the soaking liquid in the beaker so that the sample is located below the liquid surface of the soaking liquid.

[0005] Two columns are respectively arranged on both sides of the top of the bracket; the counterweight frame is a container with an opening on the top; the counterweight frame is used for placing counterweight objects; and the two ends of the cable are respectively connected to the two sides of the counterweight frame.

[0006] The first pulleys in the pulley block are respectively located at the tops of the two columns, the second pulleys in the pulley block are located at the bottoms of the two columns, the two third pulleys in the pulley block are located at the crossbeam position in the middle of the bracket, and a wire groove is provided on the cross plate. The cables pass through the first pulley, the second pulley, and the third pulley respectively, and then pass through the wire groove and are connected to the pressure plate.

[0007] A plurality of adjustment grooves connected by semicircular grooves symmetrically about the central axis are arranged in the cross beam in the middle of the bracket, and the adjustment shafts on the two third pulleys can be located in any two of the semicircular grooves in the adjustment grooves to adjust the distance between the two third pulleys.

[0008] The two columns are respectively provided with through grooves which penetrate through both ends of the column, and the side walls of the through grooves penetrate through the side walls of the column to form a linear observation port. The cable passes through the through grooves, and a wire holder is connected to the cable in the through grooves. The wire holder is provided with an indicator plate, and the indicator plate is located in the linear observation port and can move axially in the linear observation port. The side walls of the columns on the sides of the linear observation port are provided with scale values.

[0009] The indicator plate on the upper part of the wire clamp is a cross-shaped structure, extending out from the surface of the column through a linear observation port, and the bottom of the wire clamp is a conical structure.

[0010] The pressurizing plate is provided with through holes arranged in an array, so that the soaking liquid can enter the pressurizing surface of the sample, and the cables can also pass through the through holes to achieve uniform pressurization of the sample.

[0011] A bolt is respectively provided on both sides of the two supporting arms below the horizontal plate. The bolt is threadedly connected to the side wall of the supporting arm, and the front end of the bolt passes through the supporting arm. The ends of the two bolts are rotatably connected to clamping plates respectively. The two bolts can clamp and fix the sample to be tested by adjusting the distance between the two clamping plates.

[0012] The bracket is respectively provided with extension arms extending outward on both sides, and also includes an annular base and a support column connected to the base. The end of the extension arm is provided with a threaded hole, and the threaded hole is threadedly connected with an adjusting screw. The lower end of the adjusting screw is threadedly connected to the adjusting threaded hole on the support column. The height of the bracket can be adjusted by adjusting the adjusting screw.

[0013] The beneficial effects of the present invention are: The biodegradable sample pressurization experimental device of the present invention is used to apply a certain stress to the sample through a pulley system. The magnitude of the stress can be adjusted by adding weights of corresponding weights in the counterweight frame as required, and the displacement of the sample immersed in the immersion liquid can be observed and recorded in real time through the change of the position of the wire clamp, and there is no need to take out the sample for measurement, thereby avoiding the problem of adverse effects on the experimental results due to thermal expansion and contraction caused by temperature changes and the reaction between the sample and components in the air after the sample is taken out; in addition, the adjustable support column can adjust the height of the bracket, so that the entire device can adapt to the requirements of different immersion containers and immersion liquid amounts. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1It is a schematic structural diagram of the biodegradable sample pressurization experimental device of the present invention in a three-dimensional state; Figure 2 Based Figure 1 A schematic diagram of the enlarged structure of the middle part A; Figure 3 It is a schematic diagram of the main structural cross-section of the biodegradable sample pressurization experimental device of the present invention in the front view state; Figure 4 It is a schematic diagram of the partial cross-sectional structure of the crossbeam and the adjusting groove thereon and the third pulley in the matching state in the present invention.

[0015] In the figure: 1. Column; 2. Counterweight frame; 3. Counterweight; 4. First pulley; 5. Cable; 6. Linear observation port; 7. Indicator board; 8. Scale value; 9. Extension arm; 10. Support column; 11. Adjusting screw; 12. Second pulley; 13. Wire clamp; 14. Base; 15. Support arm; 16. Cross plate; 17. Wire trough; 18. Bolt; 19. Clamping plate; 20. Sample; 21. Pressure plate; 22. Adjustment groove; 23. Semicircular groove; 24. Third pulley; 25. Adjustment shaft; 26. Crossbeam; 27. Ring frame. DETAILED DESCRIPTION

[0016] The present invention is further described below in conjunction with the accompanying drawings and embodiments: Example 1: A biodegradable sample pressurization experimental device, see Figures 1 to 4 .

[0017] The device includes a bracket; two columns 1 are respectively provided on both sides of the top of the bracket, and extension arms 9 extending outward are respectively provided on both sides of the bracket. It also includes an annular base 14 and a support column 10 connected to the base 14. The end of the extension arm 9 is provided with a threaded hole, and the threaded hole is threadedly connected with an adjusting screw 11. The lower end of the adjusting screw 11 is threadedly connected to the adjusting threaded hole on the support column 10. The height of the bracket can be adjusted by adjusting the adjusting screw 11. The base 14 is a flat annular structure at the bottom, and stable support of the bracket is achieved through the base 14.

[0018] Furthermore, a counterweight frame 2 is provided on the top of the bracket. The counterweight frame 2 is a container with an open top. The counterweight frame 2 is used to place a counterweight 3, and the counterweight 3 includes weights and the like.

[0019] Furthermore, a horizontal plate 16 is provided at the bottom of the bracket, and also includes a pressure plate 21 for applying pressure to the sample, and a pulley system with a cable 5, one end of the cable 5 in the pulley system is connected to the counterweight frame 2, and the other end is connected to the pressure plate 21, and the sample 20 is located between the pressure plate 21 and the horizontal plate 16, and the counterweight frame 2 applies tension to the cable 5 and applies upward tension to the pressure plate 21 after turning the pulley group in the pulley system, thereby making the sample 20 bear pressure.

[0020] Specifically, the first pulley 4 in the pulley block is located at the top of the two columns 1, the second pulley 12 in the pulley block is located at the bottom of the two columns 1, and the two third pulleys 24 in the pulley block are located at the crossbeam 26 in the middle of the bracket. The cross plate 16 is provided with a through wire groove 17, and the cable 5 passes through the first pulley 4, the second pulley 12, and the third pulley 24 respectively, and then passes through the wire groove 17 and is connected to the pressure plate 21. Figure 3 As mentioned above, there is one cable 5 in this embodiment, but in a specific implementation, there may be two cables.

[0021] Furthermore, the pressurizing plate 21 is provided with through holes arranged in an array, so that the soaking liquid can penetrate into the pressurizing surface of the sample through the through holes. At the same time, by passing the cable 5 through two different through holes, pressurization operation can be achieved for samples of different sizes.

[0022] Furthermore, the present design also provides a bolt 18 on both sides of the two support arms 15 below the horizontal plate 16, the bolt 18 is threadedly connected to the side wall of the support arm 15, and the front end of the bolt 18 passes through the support arm, and the ends of the two bolts 18 are rotatably connected to clamping plates 19 respectively. When necessary, the two bolts can be adjusted to clamp and fix the sample 20 to be tested through the two clamping plates 19.

[0023] Furthermore, the present design also provides an adjustment groove 22 connected in sequence by a number of semicircular grooves 23 symmetrically arranged along the central axis in the cross beam 26 in the middle of the bracket. The adjustment shafts 25 on the two third pulleys 24 can be located in any two of the semicircular grooves 23 in the adjustment grooves 22 to adjust the distance between the two third pulleys 24. Through this design, when the sample is large, the distance between the two third pulleys 24 can be adjusted to avoid the influence of the cable inclination on both sides on the applied pressure and displacement measurement results.

[0024] Furthermore, in order to facilitate the intuitive observation of sample degradation and deformation, the present design also provides through grooves penetrating both ends of the two columns 1 respectively, and the side walls of the through grooves penetrate the side walls of the column 1 to form a linear observation port 6, and the cable 5 penetrates the through groove, and a wire holder 13 is connected to the cable in the through groove, and an indicator plate 7 is provided on the wire holder 13, and the indicator plate 7 is located in the linear observation port 6 and can move axially in the linear observation port 6. A scale value 8 is provided on the side wall of the column on the side of the linear observation port 6. The indicator plate 7 on the upper part of the wire holder 13 in the present design is a cross-shaped structure, extending out of the surface of the column 1 through the linear observation port, and the bottom of the wire holder 13 is a conical structure.

[0025] The use process of the biodegradable sample pressurization experimental device designed in this paper is as follows: 1. Adjust the two bolts 18 and temporarily fix the sample by clamping it with two clamping plates 19.

[0026] 2. Assemble the pulley system and place the pressure plate 21 against the bottom of the sample.

[0027] 3. Convert the pressure to be applied into the mass of the weight located in the counterweight rack.

[0028] 4. Tighten the two bolts 18 to loosen the fixation of the two clamping plates 19 on the sample.

[0029] 5. After adding enough soaking liquid into the beaker, place the beaker in a water bath, place the annular frame 27 at the bottom of the support arm 15 in the soaking liquid in the beaker and place the sample in the soaking liquid. At this time, the beaker is located inside the base 14, and the base 14 provides support for the bracket.

[0030] 6. The position of the annular frame 27 is adjusted by adjusting the adjusting screw 11 so that it is attached to the bottom of the beaker, thereby providing further support for the immersion liquid.

[0031] 7. Observe the changes on the indicator plate 7 through the scale value 8 to determine the degree of sample degradation and deformation.

[0032] The embodiments of the present invention disclose preferred embodiments, but are not limited thereto. A person skilled in the art can easily understand the spirit of the present invention based on the above embodiments and make different extensions and changes. However, as long as they do not deviate from the spirit of the present invention, they are all within the protection scope of the present invention.

Claims

1. A biodegradable sample pressurization experimental device, comprising a support; characterized in that: The top of the bracket is provided with a counterweight frame, the bottom of the bracket is provided with a horizontal plate, and also includes a pressure plate for applying pressure to the sample and a pulley system with a cable, one end of the cable is connected to the counterweight frame, and the other end is connected to the pressure plate, the sample is located between the pressure plate and the horizontal plate, the counterweight frame applies tension to the cable and applies upward tension to the pressure plate after turning the pulley group in the pulley group system, thereby pressurizing the sample; the lower end of the bracket is located in the immersion liquid in the beaker and the sample is located below the liquid surface of the immersion liquid.

2. The biodegradable sample pressurization test device according to claim 1, characterized in that: Two columns are respectively arranged on both sides of the top of the bracket; the counterweight frame is a container with an opening on the top; the counterweight frame is used for placing counterweight objects; and the two ends of the cable are respectively connected to the two sides of the counterweight frame.

3. The biodegradable sample pressurization test device according to claim 2, characterized in that: The first pulleys in the pulley block are respectively located at the tops of the two columns, the second pulleys in the pulley block are located at the bottoms of the two columns, the two third pulleys in the pulley block are located at the crossbeam position in the middle of the bracket, and a wire groove is provided on the cross plate. The cables pass through the first pulley, the second pulley, and the third pulley respectively, and then pass through the wire groove and are connected to the pressure plate.

4. The biodegradable sample pressurization test device according to claim 3, characterized in that: A plurality of adjustment grooves connected by semicircular grooves symmetrically about the central axis are arranged in the cross beam in the middle of the bracket, and the adjustment shafts on the two third pulleys can be located in any two of the semicircular grooves in the adjustment grooves to adjust the distance between the two third pulleys.

5. The biodegradable sample pressurization test device according to claim 4, characterized in that: The two columns are respectively provided with through grooves which penetrate through both ends of the column, and the side walls of the through grooves penetrate through the side walls of the column to form a linear observation port. The cable passes through the through grooves, and a wire holder is connected to the cable in the through grooves. The wire holder is provided with an indicator plate, and the indicator plate is located in the linear observation port and can move axially in the linear observation port. The side walls of the columns on the sides of the linear observation port are provided with scale values.

6. The biodegradable sample pressurization test device according to claim 5, characterized in that: The indicator plate on the upper part of the wire clamp is a cross-shaped structure, extending out from the surface of the column through a linear observation port, and the bottom of the wire clamp is a conical structure.

7. The biodegradable sample pressurization test device according to claim 1, characterized in that: The pressure plate is provided with through holes arranged in an array, and the cables pass through two through holes on the pressure plate.

8. The biodegradable sample pressurization test device according to claim 1, characterized in that: A bolt is respectively provided on both sides of the two supporting arms below the horizontal plate. The bolt is threadedly connected to the side wall of the supporting arm, and the front end of the bolt passes through the supporting arm. The ends of the two bolts are rotatably connected to clamping plates respectively. The two bolts can clamp and fix the sample to be tested by adjusting the distance between the clamping plates.

9. The biodegradable sample pressurization test device according to claim 1, characterized in that: The bracket is respectively provided with extension arms extending outward on both sides, and also includes an annular base and a support column connected to the base. The end of the extension arm is provided with a threaded hole, and the threaded hole is threadedly connected with an adjusting screw. The lower end of the adjusting screw is threadedly connected to the adjusting threaded hole on the support column. The height of the bracket can be adjusted by adjusting the adjusting screw.

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