A sampling cone for reducing matrix effect in plasma mass spectrometer

Abstract

The invention relates to a sampling cone for reducing the matrix effect of a plasma mass spectrometer, which is applied to the field of mass spectrometer sampling cones. The sample of a solution in the sampling cone is reduced by assisting the heat dissipation and cooling of the sampling cone. On the basis of the existing heat dissipation of heat dissipation by heat dissipation columns and circulating coolers, a "J"-shaped design is used to enable a second area and a third area where a water-cooling pipe contacts a cooling pipe to maintain an initial cooling effect, thereby maintaining the cooling quality of the second area and the third area consistent. A branch pipe with a folding design can cool the first area, thereby maintaining the cooling effect of the cooling pipe consistent. When the water-cooling pipe exchanges heat, an air bag strip expands and squeezes, thereby increasing the heat exchange contact area between the water-cooling pipe and the cooling pipe, thereby improving the heat dissipation efficiency. In addition, with the cooperation of an inflatable strip and an air supply hose, the heat exchange efficiency can be adjusted, thereby further improving the heat exchange uniformity.

Description

Technical Field

[0001] The invention relates to a sampling cone, in particular to a sampling cone applied to the field of mass spectrometer sampling cones and capable of reducing the matrix effect of a plasma mass spectrometer. Background Art

[0002] The matrix effect refers to the influence of other components in the sample other than the element to be measured on the analysis results during the analysis of the inductively coupled plasma mass spectrometer. This influence may come from a variety of factors, including ionization suppression, space charge effect and synergistic effect. In the analysis of plasma mass spectrometer, the matrix effect is a complex and important issue, which directly affects the accuracy and precision of the analysis. Controlling the sample concentration in the sampling cone is an effective means to reduce the matrix effect.

[0003] The patent specification with publication number CN212461599U discloses a new type of inductively coupled plasma mass spectrometer sampling cone. The new type of inductively coupled plasma mass spectrometer sampling cone has a reasonable structure. A clamp is provided on the circumference of the outer ring of the plane part. When disassembling, the clamp can be removed together with the cone, which solves the problem that the traditional sampling cone is cumbersome and easy to fall off during the disassembly and assembly process.

[0004] Existing sampling cones generally use a combination of heat dissipation columns and circulating coolers to achieve cooling of the sampling cone, so as to avoid excessive temperature inside the sampling cone, which may cause internal sample evaporation and increase sample concentration, thereby controlling the matrix effect inside the sampling cone. However, during the water cooling process, the cooling tube is wrapped around the surface of the sampling cone, and the distance between the water inlet pipe and the water outlet pipe is relatively long, resulting in the cooling effect of the area near the water inlet pipe on the surface of the sampling cone being better than that of the area near the water outlet pipe, resulting in inconsistent cooling effect on the surface of the sampling cone. Summary of the invention

[0005] In view of the above-mentioned prior art, the technical problem to be solved by the present invention is how to achieve consistency in the cooling quality of the sampling cone surface during the cooling process of the sampling cone.

[0006] In order to solve the above problems, the present invention provides a sampling cone for reducing the matrix effect of a plasma mass spectrometer, comprising a sampling cone with a plane portion and a conical portion, a heat dissipation column is installed on the plane portion of the sampling cone, a plurality of heat dissipation fins are installed on the surface of the heat dissipation column, a cooling pipe is spirally wound on the outer surface of the conical portion of the sampling cone, a hose is connected to the water inlet of the cooling pipe, and a branch pipe is connected to the surface of the hose;

[0007] The inner walls of the water inlet and the water outlet of the cooling pipe are both installed with sealing plugs, and a heat insulation strip is connected between the two sealing plugs, and the heat insulation strip divides the inside of the cooling pipe into two independent spaces. Two water-cooling pipes are installed inside the sealing plug at the water inlet position of the cooling pipe, and the two water-cooling pipes are arranged in a "J" shape inside the cooling pipe. The vertical projections of the two water-cooling pipes in the cooling pipe are symmetrically arranged. A heat insulation disk with the same diameter as the inner diameter of the cooling pipe is provided at the position where the vertical projections of the two water-cooling pipes in the cooling pipe overlap, and the two water-cooling pipes pass through the inside of the heat insulation disk;

[0008] The cooling pipe is composed of a heat-conducting part and a heat-insulating part, wherein the heat-conducting part and the heat-insulating part are arranged symmetrically about the heat-insulating strip, an airbag strip is installed inside the heat-conducting part, and the airbag strip is located between the water-cooling pipe and the heat-insulating strip;

[0009] The tip of the conical part of the sampling cone is threadedly connected with an insert, and the inner wall of the end of the sampling cone plane away from the conical part is provided with a groove, in which a high-temperature latex sealing ring is connected.

[0010] In the above-mentioned sampling cone for reducing the matrix effect of the plasma mass spectrometer, on the basis of cooling and heat dissipation by the heat dissipation column and the circulating cooler, the cooling effect of the cooling pipe on the surface of the sampling cone is kept consistent through the "J"-shaped water cooling pipe and the folded branch pipe.

[0011] As a further improvement of the present application, the heat conducting part is made of a heat conducting material, and the heat conducting part is in contact with the surface of the sampling cone, and the heat insulating part is made of a heat insulating material.

[0012] As a further improvement of the present application, the tail end of the branch pipe extends to the inside of the water outlet end of the cooling pipe, and the water outlet of the branch pipe is located in the position area of ​​the water outlet of the cooling pipe, the branch pipe is located above the water cooling pipe, and the height of the airbag strip in the initial state is greater than the installation height of the branch pipe.

[0013] As a further improvement of the present application, the heat dissipation fins are of wave-shaped design and are made of elastic heat-conducting material.

[0014] As a further improvement of the present application, the length of the heat dissipation column is greater than the height of the conical portion of the sampling cone, and the top and bottom ends of the heat dissipation fins are connected to plug-in blocks, and the heat dissipation fins are plugged into plug-in slots provided on the surface of the heat dissipation column through the plug-in blocks.

[0015] As another improvement of the present application, an air filling strip is provided in the water cooling tube, and an air supply hose which is in communication with the air filling strip is installed through the interior of the heat insulation strip, and an electronic valve is installed on the surface of the air supply hose.

[0016] As another improved supplement of the present application, a plurality of temperature sensors are installed on the surface of the cooling pipe, and the temperature sensors are connected to the electronic valve signal.

[0017] As another improved supplement of the present application, an electric vacuum pump connected to an air supply hose is installed on one side of the sampling cone, the inflation strips inside the water-cooling tube are arranged in three sections, and adjacent inflation strips in each water-cooling tube are isolated.

[0018] To summarize, the present application reduces the matrix effect in the sampling cone by assisting the sampling cone in dissipating heat and cooling the solution sample in the sampling cone. On the basis of the existing cooling and heat dissipation of the heat dissipation column and the circulating cooler, the "J"-shaped design can make the water-cooled pipe and the cooling pipe contact area No. 2 and area No. 3 maintain the initial cooling effect, so that the cooling quality of area No. 2 and area No. 3 remains consistent, and the folded branch pipe can cool area No. 1, so that the cooling effects of area No. 1, area No. 2 and area No. 3 remain consistent, and when the water-cooled pipe exchanges heat, the airbag strip expands and squeezes, increasing the heat exchange contact area between the water-cooled pipe and the cooling pipe, improving the heat dissipation efficiency, and with the cooperation of the inflation strip and the air supply hose, the heat exchange efficiency can be adjusted to further improve the heat exchange uniformity. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the overall structure of the first implementation method of the present application;

[0020] Figure 2 This is a schematic diagram of the installation of the embedded sheet and high-temperature latex sealing ring in the sampling cone of the first embodiment of the present application;

[0021] Figure 3 This is a diagram of the heat conducting part and the heat insulating part of the first embodiment of the present application;

[0022] Figure 4 This is a diagram showing the arrangement of the branch pipes in the cooling pipe according to the first embodiment of the present application;

[0023] Figure 5 This is a diagram showing the arrangement of two water cooling pipes in a cooling pipe according to the first embodiment of the present application;

[0024] Figure 6 This is a schematic diagram of the path of the coolant in the branch pipe of the first embodiment of the present application;

[0025] Figure 7 This is a state diagram of the airbag strip before and after expansion of the first embodiment of the present application;

[0026] Figure 8 This is a schematic diagram of the installation of the inflatable strip and the air supply hose according to the second embodiment of the present application;

[0027] Fig. 9 This is a state diagram of the second embodiment of the present application where the expansion of the inflatable strip drives the deformation of the water cooling tube;

[0028] Fig.10 This is a state diagram of different expansion degrees of the segmented inflatable strip of the second embodiment of the present application.

[0029] Description of the numbers in the figure:

[0030] 1. Sampling cone; 2. Cooling tube; 3. Heat dissipation column; 4. Branch pipe; 5. Heat insulation strip; 6. Air bag strip; 7. Water cooling tube; 8. Heat insulation plate; 21. Heat conduction part; 22. Heat insulation part; 71. Inflatable strip; 72. Air supply hose; 9. Sealing plug. DETAILED DESCRIPTION

[0031] Two implementation modes of the present application are described in detail below with reference to the accompanying drawings.

[0032] The first implementation method:

[0033] Figure 1-Figure 5 A sampling cone for reducing the matrix effect of a plasma mass spectrometer is shown, comprising a sampling cone 1 with a plane portion and a conical portion, a heat dissipation column 3 is installed on the plane portion of the sampling cone 1, a plurality of heat dissipation fins are installed on the surface of the heat dissipation column 3, a cooling tube 2 is spirally wound on the outer surface of the conical portion of the sampling cone 1, a hose is connected to the water inlet of the cooling tube 2, and a branch pipe 4 is connected to the surface of the hose;

[0034] The inner walls of the water inlet and the water outlet of the cooling pipe 2 are both installed with sealing plugs 9, and the middle of the two sealing plugs 9 is connected with a heat insulation strip 5, and the heat insulation strip 5 divides the inside of the cooling pipe 2 into two independent spaces. Two water-cooling pipes 7 are installed through the inside of the sealing plug 9 at the water inlet position of the cooling pipe 2, and the two water-cooling pipes 7 are arranged in a "J" shape inside the cooling pipe 2. The vertical projections of the two water-cooling pipes 7 in the cooling pipe 2 are symmetrically arranged. The position where the vertical projections of the two water-cooling pipes 7 in the cooling pipe 2 overlap is provided with a heat insulation disk 8 with the same diameter as the inner diameter of the cooling pipe 2, and the two water-cooling pipes 7 pass through the inside of the heat insulation disk 8;

[0035] The cooling pipe 2 is composed of a heat conducting part 21 and a heat insulating part 22, wherein the heat conducting part 21 and the heat insulating part 22 are arranged symmetrically about the heat insulating strip 5, and an air bag strip 6 is installed inside the heat conducting part 21, and the air bag strip 6 is located between the water cooling pipe 7 and the heat insulating strip 5;

[0036] The tip of the conical part of the sampling cone 1 is threadedly connected with an insert, and the inner wall of the end of the plane part of the sampling cone 1 away from the conical part is provided with a groove, and a high-temperature latex sealing ring is connected in the groove.

[0037] The tail end of the branch pipe 4 extends to the inside of the water outlet end of the cooling pipe 2, and the water outlet of the branch pipe 4 is located in the position area of ​​the water outlet of the cooling pipe 2. The branch pipe 4 is located above the water cooling pipe 7, and the height of the airbag strip 6 in the initial state is greater than the installation height of the branch pipe 4.

[0038] Specifically, during the operation of the sampling cone, the temperature at its outlet is relatively high, which may cause evaporation of the internal solution sample, thereby increasing the concentration of the sample, which is not conducive to reducing the matrix effect. Therefore, during the cooling of the sampling cone 1, the heat dissipation column 3 and the heat dissipation fins on the surface can both play an auxiliary heat dissipation role, and will also cooperate with the circulating cooler (not shown in the figure) arranged on one side of the sampling cone 1 and connected to the cooling tube 2 to enhance the heat dissipation effect.

[0039] By designing an insert, the sample matrix effect can be better reduced, and the matrix tolerance can be improved when processing complex matrices or high-salt samples, thereby indirectly improving the analytical sensitivity of the mass spectrometer. It can also reduce the sedimentation when passing through the cone hole of the sampling cone 1, and reduce the risk of cone hole clogging. In addition, the design of the high-temperature latex sealing ring can make the sealing better.

[0040] In the prior art, the coolant is sent into the cooling pipe 2 through a circulating cooler, and then returns to the circulating cooler through the water outlet of the cooling pipe 2, and the cooled coolant is again sent to the cooling pipe 2 for circulating heat dissipation.

[0041] However, in the prior art, taking the present invention as an example, when the cooling tube 2 dissipates heat, the water inlet of the cooling tube 2 is located at the upper position of the sampling cone 1, and the water outlet of the cooling tube 2 is located at the lower position of the sampling cone 1. This causes the cooling effect at the water inlet of the cooling tube 2 to be better than the cooling effect at the water outlet, because the coolant has been exchanged for a period of time at the water outlet, and the cooling effect of the coolant is poor.

[0042] In the present invention, the coolant entering the water inlet of the cooling tube 2 enters two water-cooling tubes 7 respectively, one of which (marked as tube No. 1) is close to the surface of the sampling cone 1, and performs normal heat exchange operation on the No. 3 area. Under the thermal expansion and extrusion of the airbag strip 6 in the heat-conducting part 21, the water-cooling tube 7 is squeezed and deformed, and the contact area with the cooling tube 2 is increased (such as Figure 7 As shown), the heat exchange efficiency is enhanced, and at the same time, another water-cooled tube 7 (marked as tube No. 2) is isolated in the insulation space formed by the insulation part 22, the insulation plate 8 and the insulation strip 5 to maintain the cooling effect until the two water-cooled tubes 7 exchange the contact parts with the cooling tube 2 (that is, when the No. 1 tube and the No. 2 tube exchange their placement positions), the part of the No. 2 tube that was initially isolated to maintain the cooling effect is able to contact the cooling tube 2, and the surface of the No. 2 area is initially cooled.

[0043] At the same time, the branch pipe 4 in the folded state is cooled in the first area (eg Figure 6 As shown), the cooling effects of area 1, area 2 and area 3 are all maintained in the initial cooling state of the water-cooling pipe 7, thereby achieving consistency in cooling quality.

[0044] During the heat dissipation process, area No. 1 is located near the bottom of the sampling cone 1, area No. 2 is located in the middle of the sampling cone 1, and area No. 3 is located near the top of the sampling cone 1.

[0045] The water outlets of the two water cooling pipes 7 and the water outlet of the branch pipe 4 are both located within the water outlet position of the cooling pipe 2. The coolant after heat exchange treatment can be discharged centrally through the water outlet of the cooling pipe 2 to achieve circulation treatment.

[0046] The heat conducting part 21 is made of a heat conducting material, and the heat conducting part 21 is in contact with the surface of the sampling cone 1 , and the heat insulating part 22 is made of a heat insulating material.

[0047] Specifically, the heat conducting portion 21 contacts the surface of the sampling cone 1 to achieve heat exchange operation.

[0048] The heat dissipation fins are designed in a wave shape and are made of elastic heat-conducting material.

[0049] The length of the heat dissipation column 3 is greater than the height of the conical portion of the sampling cone 1 , and the top and bottom ends of the heat dissipation fins are connected with plug-in blocks, and the heat dissipation fins are plugged into the plug-in slots provided on the surface of the heat dissipation column 3 through the plug-in blocks.

[0050] Specifically, the heat sink fins are in contact with the surface of the heat sink column 3 when in the plugged state. When the dust on the surface of the heat sink fins needs to be cleaned, the plug-in blocks on the surface of the heat sink fins can be detached from the plug-in slots, and then the cleaning sheet can be wrapped around the surface of the heat sink fins. One end of the heat sink fins can be fixed, and then the cleaning sheet in the wrapped state can be driven to move along the surface of the heat sink fins to clean the dust on the surface of the heat sink fins.

[0051] In addition, the height design of the heat dissipation column 3 ensures that the narrow cone opening of the sampling cone 1 will not contact the placement surface even when it is in an inverted state, thereby avoiding bumps and damages.

[0052] The second implementation method:

[0053] Figure 8-Figure 9 It is shown that an air-filling strip 71 is provided in the water-cooling tube 7 , and an air supply hose 72 which is in communication with the air-filling strip 71 is installed through the interior of the heat-insulating strip 5 , and an electronic valve is installed on the surface of the air supply hose 72 .

[0054] An electric vacuum pump (not shown) connected to the air supply hose 72 is installed on one side of the sampling cone 1. The air-filled strips 71 inside the water-cooling tube 7 are arranged in three sections, and adjacent air-filled strips 71 in each water-cooling tube 7 are isolated from each other.

[0055] A plurality of temperature sensors are installed on the surface of the cooling pipe 2, and the temperature sensors are connected to the electronic valve signal.

[0056] Different from the first embodiment, this embodiment mainly aims at improving the cooling of the airbag strip 6 and the water-cooling tube 7, thereby affecting the expansion and extrusion effect.

[0057] Specifically, when heat is dissipated, the airbag strip 6 contacts the water-cooling tube 7 and the temperature is reduced synchronously, thereby affecting the extrusion deformation effect of the water-cooling tube 7. At this time, the design of the built-in inflation strip 71 can be used to increase the contact area with the heat-conducting portion 21 of the cooling tube 2 while the water-cooling tube 7 is deformed, and the inflation design is continuously performed at the same time, so that the expansion degree of the inflation strip 71 is not affected by the temperature of the water-cooling tube 7 itself (such as Fig. 9 as shown).

[0058] In addition, the surface temperature sensor can detect the cooling effect of different areas of the sampling cone 1. When the temperature of a local area on the surface of the sampling cone 1 is higher than that of other areas, the inflation degree of the area can be increased (by adjusting the flow rate of the electronic valve), so that the expansion degree of the inflation strip 71 in different areas is different (such as Fig.10 As shown), the deformation degree of the water-cooling pipe 7 in this area is strengthened, and the heat dissipation contact area is further increased, thereby helping to achieve uniform heat dissipation.

[0059] Moreover, the electric vacuum pump can both inflate and exhaust air, so that the deflation and inflation operations of the inflatable strip 71 can be realized.

[0060] Alternatively, the airbag strip 6 may be replaced by the inflatable strip 71 (that is, the airbag strip 6 is eliminated), so that the inflatable strip 71 is inflated and deformed alone to perform the corresponding deformation processing of the water-cooling tube 7 .

[0061] In summary, the present application reduces the solution sample in the sampling cone by assisting the sampling cone in heat dissipation and cooling when reducing the matrix effect in the sampling cone. On the basis of the existing heat dissipation column 3 and the circulating cooler cooling and heat dissipation, through the "J"-shaped design, the water-cooling tube 7 can be in contact with the cooling tube 2 in area No. 2 and area No. 3. The cooling quality of area No. 2 and area No. 3 is kept consistent, and the folded branch pipe 4 can cool area No. 1, so that the cooling effects of area No. 1, area No. 2 and area No. 3 are kept consistent. When the water-cooling tube 7 exchanges heat, the airbag strip 6 expands and squeezes, increasing the heat exchange contact area between the water-cooling tube 7 and the cooling tube 2, improving the heat dissipation efficiency, and can achieve adjustable heat exchange efficiency with the cooperation of the inflation strip 71 and the air supply hose 72, further improving the heat exchange uniformity.

[0062] In view of current practical needs, the above-mentioned implementation mode adopted in this application is not limited to the scope of protection. Various changes made within the knowledge scope of technical personnel in this field without departing from the concept of this application still fall within the scope of protection of the present invention.

Claims

1. A sampling cone for reducing the matrix effect of a plasma mass spectrometer, comprising a sampling cone (1) having a planar portion and a conical portion, a heat dissipation column (3) being mounted on the planar portion of the sampling cone (1), and a plurality of heat dissipation fins being mounted on the surface of the heat dissipation column (3), characterized in that: A cooling pipe (2) is spirally wound on the outer surface of the conical portion of the sampling cone (1); a hose is connected to the water inlet of the cooling pipe (2), and a branch pipe (4) is connected to the surface of the hose; The inner walls of the water inlet and the water outlet of the cooling pipe (2) are both installed with sealing plugs (9), a heat insulation strip (5) is connected between the two sealing plugs (9), and the heat insulation strip (5) divides the interior of the cooling pipe (2) into two independent spaces, two water cooling pipes (7) are installed through the interior of the sealing plug (9) at the water inlet position in the cooling pipe (2), and the two water cooling pipes (7) are arranged in a "J" shape inside the cooling pipe (2), the vertical projections of the two water cooling pipes (7) in the cooling pipe (2) are symmetrically arranged, and a heat insulation disk (8) with the same diameter as the inner diameter of the cooling pipe (2) is provided at the position where the vertical projections of the two water cooling pipes (7) in the cooling pipe (2) overlap, and the two water cooling pipes (7) pass through the interior of the heat insulation disk (8); The cooling pipe (2) is composed of a heat conducting portion (21) and a heat insulating portion (22), wherein the heat conducting portion (21) and the heat insulating portion (22) are arranged symmetrically with respect to the heat insulating strip (5), an air bag strip (6) is installed inside the heat conducting portion (21), and the air bag strip (6) is located between the water cooling pipe (7) and the heat insulating strip (5); The tip of the conical portion of the sampling cone (1) is threadedly connected with an insert, and the inner wall of the end of the plane portion of the sampling cone (1) away from the conical portion is provided with a groove, and a high-temperature latex sealing ring is connected in the groove.

2. The sampling cone for reducing the matrix effect of plasma mass spectrometer according to claim 1, characterized in that: The heat conducting portion (21) is made of a heat conducting material, and the heat conducting portion (21) is in contact with the surface of the sampling cone (1); and the heat insulating portion (22) is made of a heat insulating material.

3. The sampling cone for reducing the matrix effect of plasma mass spectrometer according to claim 1, characterized in that: The tail end of the branch pipe (4) extends to the inside of the water outlet end of the cooling pipe (2), and the water outlet of the branch pipe (4) is located in the position area of ​​the water outlet of the cooling pipe (2). The branch pipe (4) is located above the water cooling pipe (7), and the height of the airbag strip (6) in the initial state is greater than the installation height of the branch pipe (4).

4. The sampling cone for reducing the matrix effect of plasma mass spectrometer according to claim 1, characterized in that: The heat dissipation fins are designed in a wave shape and are made of elastic heat-conducting material.

5. The sampling cone for reducing the matrix effect of plasma mass spectrometer according to claim 4, characterized in that: The length of the heat dissipation column (3) is greater than the height of the conical portion of the sampling cone (1), and the top and bottom ends of the heat dissipation fins are both connected to plug-in blocks, and the heat dissipation fins are plugged into plug-in slots provided on the surface of the heat dissipation column (3) via the plug-in blocks.

6. The sampling cone for reducing the matrix effect of plasma mass spectrometer according to claim 1, characterized in that: An air-filling strip (71) is arranged in the water-cooling tube (7), and an air supply hose (72) which is in communication with the air-filling strip (71) is installed through the interior of the heat-insulating strip (5), and an electronic valve is installed on the surface of the air supply hose (72).

7. The sampling cone for reducing the matrix effect of plasma mass spectrometer according to claim 6, characterized in that: An electric vacuum pump connected to an air supply hose (72) is installed on one side of the sampling cone (1); the air-filled strips (71) inside the water-cooling tube (7) are arranged in three sections, and adjacent air-filled strips (71) in each water-cooling tube (7) are isolated from each other.

8. The sampling cone for reducing the matrix effect of plasma mass spectrometer according to claim 7, characterized in that: A plurality of temperature sensors are installed on the surface of the cooling tube (2), and the temperature sensors are connected to the electronic valve signal.

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