Sampling tube capable of adaptively releasing preservative and method for improving dispersion effect of preservative

By designing a sampling tube that adaptively releases preservatives and improving the dispersion effect of preservatives, we solve the problem of not adding preservatives or not adding them in time, which affects the accuracy of urine testing, and achieve timely, uniform dispersion and efficient release of preservatives. , ensuring the accuracy of urine test results.

CN119327527AInactive Publication Date: 2025-01-21WESTCHINA-FRONTIER PHARMATECH CO LTD
View PDF 5 Cites 0 Cited by

Patent Information

Application Number
CN202411760462.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-03
Publication Date
2025-01-21
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In the prior art, the accuracy of urine test results is affected due to the failure of preservatives or the failure to add them in time.

Method used

Design a sampling tube that adaptively releases preservatives. The tube body is provided with a second cavity connected to the first cavity, and a solid preservative is laid in the second cavity. When urine is collected, the solid preservative is automatically released and dispersed. The method to improve the dispersion effect of the preservative is to dissolve thymol in a volatile solvent and quickly dry it to form a microporous structure to improve the release efficiency.

Benefits of technology

It ensures the timely addition and uniform dispersion of preservatives, improves the accuracy of urine test results, and further enhances the release efficiency of preservatives by improving the dispersion effect.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119327527A_ABST
    Figure CN119327527A_ABST
Patent Text Reader

Abstract

The invention provides a sampling tube capable of self-adaptively releasing a preservative and a method for improving the dispersion effect of the preservative in order to solve the problem that the detection result is affected due to the fact that the preservative is not added or not added in time in the prior art, and belongs to the technical field of test analysis. The sampling tube capable of adaptively releasing the preservative comprises a tube body and a cover, a first accommodating cavity is formed in the pipe body; a second accommodating cavity is formed in the first accommodating cavity; the second containing cavity is communicated with the first containing cavity, and a solid preservative is laid in the second containing cavity. The method comprises the following steps: dissolving thymol by utilizing a volatile solvent, and then quickly drying to remove the volatile solvent. The second containing cavity communicated with the first containing cavity is designed in the pipe body, and the solid preservative is laid in the second containing cavity, so that the problem that the detection result is affected due to the fact that the preservative is not added or not added in time is solved, and the accuracy of the detection result is guaranteed. Meanwhile, the volatile solvent improves the dispersion effect of the preservative.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention belongs to the technical field of testing and analysis, and in particular relates to a sampling tube capable of adaptively releasing a preservative and a method for improving the dispersion effect of the preservative. Background Art

[0002] Routine urine testing is of great significance in animal GLP (Good Laboratory Practice) experiments. Urine specimens contain a large number of biomarkers, which provide key information about the physiological status of animals, drug metabolism, toxic effects, etc. Urinalysis can perform semi-quantitative / qualitative testing of single or multiple chemical indicators in animal urine. Common indicators include dry chemical components [pH, urine specific gravity (SG), protein (PRO), glucose (GLU), ketone bodies (KET), etc.] and urine formed element analysis (white blood cells, red blood cells, casts, crystals, etc.), which can provide reference for clinical testing and diagnosis and non-clinical drug research.

[0003] For animal experiments, since animal urination is not controlled by human will, its urine excretion is random, and it is difficult to collect, send for inspection, and test urine in a timely manner within the specified time after it is produced. Therefore, choosing an appropriate dose of preservatives is an effective means to ensure the stability of urine. However, there are still some potential problems with the addition of urine preservatives, which affect the accuracy of urine test results, as follows:

[0004] 1. Compliance issues with adding preservatives: Thymol (thymol) solution is colorless and transparent. It is impossible to visually determine whether preservatives have been added during collection or inspection. If the operator forgets to add preservatives, the urine sample will become unstable and deteriorate, affecting the accuracy of the results.

[0005] 2. Timely addition of preservatives: If preservatives are not added in time after animal urine is collected, it will also affect the stability of the urine sample. Summary of the invention

[0006] In order to solve the problem in the prior art that the test results are affected by the fact that the preservatives are not added or are not added in time, the present invention provides a sampling tube that can adaptively release the preservative. A second cavity that is connected to the first cavity is designed to be arranged in the tube body from the bottom of the first cavity, and a solid preservative is laid in the second cavity. When urine is collected by the sampling tube, the solid preservative immediately contacts the urine and is automatically released and dispersed, thereby solving the problem that the test results are affected by the fact that the preservatives are not added or are not added in time, and ensuring the accuracy of the test results.

[0007] At the same time, the present invention also provides a method for improving the dispersion effect of preservatives. Thymol is dissolved by a volatile solvent and then quickly dried to remove the volatile solvent. This will cause the interior of the remaining thymol to have a large number of microporous structures, and the compactness and density of its own powder accumulation will be reduced, so that it has a larger contact area when in contact with urine, thereby accelerating its release and dispersion process in urine and improving the dispersion effect.

[0008] The technical solution adopted by the present invention is:

[0009] A sampling tube capable of adaptively releasing a preservative comprises a tube body and a cover, wherein the interior of the tube body is a first cavity; an independent second cavity is arranged from the bottom of the first cavity; from bottom to top, corresponding parts of the second cavity are all connected to the first cavity; and a solid preservative is laid in the second cavity starting from the bottom of the second cavity.

[0010] Furthermore, starting from the bottom of the tube body, one or more grooves are opened on the inner side wall of the tube body along its own height direction; the inner area of ​​the groove is the second cavity.

[0011] Furthermore, starting from the bottom of the tube body, one or more grooves are opened on the inner wall of the tube body along the spiral ascending direction; the inner area of ​​the groove is the second cavity.

[0012] Furthermore, starting from the bottom of the tube body, a plurality of grooves are provided on the inner side wall of the tube body along its circumferential direction; the inner area of ​​the groove is the second cavity.

[0013] Furthermore, starting from the bottom of the tube body, one or more groups of partition components protruding from the inner wall of the tube body are formed on the inner wall of the tube body along its own height direction; the partition component includes two partition protrusions, and the area between the two partition protrusions is the second cavity.

[0014] Furthermore, starting from the bottom of the tube body, one or more groups of partition components protruding from the inner wall of the tube body are formed on the inner wall of the tube body along a spiral ascending direction; the partition component includes two partition protrusions, and the area between the two partition protrusions is the second cavity.

[0015] Furthermore, starting from the bottom of the tube body, a plurality of partition components protruding from the inner wall of the tube body are formed in the circumferential direction on the inner wall of the tube body; the partition components include two partition protrusions, and the area between the two partition protrusions is the second cavity.

[0016] Furthermore, starting from the bottom of the tube body, one or more medicine containing tubes are opened along the height direction of the tube body in an area that is not in direct contact with the inner wall; the upper and lower ends of the medicine containing tube are connected, and a notch is opened on the tube wall of the medicine containing tube; the notch starts from the lower end of the medicine containing tube and ends at the upper end of the medicine containing tube; the internal area of ​​the medicine containing tube is the second cavity.

[0017] Furthermore, a scale is formed on the outer side wall of the tube body along its own height direction.

[0018] Based on the same inventive concept, the present invention also provides a method for improving the dispersion effect of preservatives. First, a preset mass of thymol is mixed with a preset volume of a volatile organic solvent to obtain a thymol solution. Then, the thymol solution is introduced into a second cavity in the tube body, and the volatile organic solvent is quickly dried to remove the remaining thymol. The remaining thymol adheres to the inner wall of the second cavity, and finally a sampling tube for adaptively releasing preservatives as described above is obtained.

[0019] The beneficial effects of the present invention are:

[0020] 1. The present invention designs a sampling tube that can adaptively release preservatives, and specifically designs a second cavity that is connected to the first cavity and starts from the bottom of the first cavity in the tube body, and a solid preservative is laid in the second cavity; when urine is collected by the sampling tube, the solid preservative immediately contacts the urine and is automatically released and dispersed, thereby solving the problem of the test results being affected by the failure to add the preservative or the failure to add it in time, and ensuring the accuracy of the test results.

[0021] 2. The present invention also provides a method for improving the dispersion effect of preservatives. On the one hand, since volatile organic solvents are used to dissolve thymol, the uniformity of thymol laid in the second cavity can be guaranteed in the end; on the other hand, the volatile organic solvents will cause the remaining thymol to have a large number of microporous structures in the interior during the rapid drying process, and the compactness and density of the powder itself will be reduced, so that it has a larger contact area when in contact with urine, thereby accelerating its release and dispersion process in urine and improving the dispersion effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0023] Figure 1 This is a front view of a sampling tube for adaptively releasing preservatives in Example 1.

[0024] Figure 2 A top view of a sampling tube for adaptively releasing preservatives in Example 1 (without the cap).

[0025] Figure 3 A perspective view of a sampling tube for adaptive release of preservative in Example 2 (without the cap).

[0026] Figure 4 This is a front view of a sampling tube for adaptively releasing preservatives in Example 3.

[0027] Figure 5 This is a front view of a sampling tube for adaptively releasing preservatives in Example 4.

[0028] Figure 6 A top view of a sampling tube for adaptively releasing preservatives in Example 4 (without the cap).

[0029] Figure 7 A perspective view of a sampling tube for adaptive release of preservative in Example 5 (without the cap).

[0030] Figure 8 This is a front view of a sampling tube for adaptively releasing preservatives in Example 6.

[0031] Fig. 9 This is a schematic diagram of the structure of a tube body that adaptively releases preservatives in Example 7 (excluding the cap).

[0032] Fig.10 This is a schematic diagram of the structure of a tube body that adaptively releases preservatives in Example 8 (excluding the cap).

[0033] Fig.11 A front view of a sampling tube for adaptively releasing preservatives in Example 11.

[0034] Fig.12 A top view of a sampling tube for adaptively releasing preservatives in Example 11 (without the cap).

[0035] Among them: 1-tube body, 2-cover; 3-partition component; 31-partition protrusion; 4-groove; 5-accommodating groove-shaped member; 6-first cavity; 7-second cavity; 8-drug tube; 81-notch. DETAILED DESCRIPTION

[0036] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0037] The disclosure below provides many different embodiments or examples to realize different structures of the present invention. In order to simplify the disclosure of the present invention, the parts and settings of specific examples are described below. Of course, they are only examples, and the purpose is not to limit the present invention.

[0038] The embodiments of the invention are described in detail below with reference to the accompanying drawings.

[0039] Example 1

[0040] This embodiment provides a sampling tube that releases preservatives in an adaptive manner, referring to Figure 1 to Figure 2 , which includes a tube body 1 and a cover 2. The tube body 1 and the cover 2 are mostly made of plastic (such as PE, PP, PVC, etc.) by injection molding, which is low in cost and corrosion-resistant. The top of the tube body 1 is open and transparent; the cover 2 covers the open top of the tube body 1.

[0041] On the inner side of the tube body 1, starting from the bottom of the tube body 1, a group of partition components 3 protruding from the inner wall of the tube body 1 is formed on the inner wall of the tube body 1 along its own height direction; the partition component 3 includes two parallel and oppositely arranged partition protrusions 31; the groove area formed between the two partition protrusions 31 in the same group is the second cavity 7; the area in the tube body 1 except the second cavity 7 is the first cavity 6; the first cavity 6 and the second cavity 7 are connected.

[0042] A solid preservative is laid in the second cavity 7; the solid preservative may be thymol (thymol) or the like. In specific operation, isopropyl alcohol or the like may be used as a solvent to prepare a thymol solution with a mass concentration of 10%, and then the thymol solution is introduced into the second cavity 7, and then the solvent is quickly air-dried to remove the solvent, and the remaining thymol adheres to the inner wall of the second cavity 7 to obtain the solid preservative.

[0043] In this embodiment, in order to ensure the accuracy of the internal volume of the tube body 1, the volume occupied by the separation protrusion 31 and the solid preservative needs to be removed when forming scales on the outer wall of the tube body 1 along its own height direction.

[0044] In this embodiment, the length of the partition protrusion 31 can be set according to the requirements. For example, along the height direction of the tube body 1, the lower end of the partition protrusion 31 starts from the bottom of the first cavity 6 (i.e., the connection between the inner side wall and the inner bottom wall), and the upper end of the partition protrusion 31 ends at the top of the first cavity 6 (i.e., the open end). For another example, along the height direction of the tube body 1, the lower end of the partition protrusion 31 starts from the bottom of the first cavity 6 (i.e., the connection between the inner side wall and the inner bottom wall), and the upper end of the partition protrusion 31 ends at a position 5 to 10 mm away from the top of the first cavity 6 (i.e., the open end).

[0045] When urine is collected using the sampling tube in this embodiment, after the collected urine to be tested is added into the first cavity 6, since the first cavity 6 and the second cavity 7 are interconnected, the solid preservative is quickly and automatically released and dispersed after contacting the urine.

[0046] Compared with the traditional method of adding preservatives after sampling, the sampling tube of this embodiment has the preservative placed in the sampling tube before adding the urine to be tested, so the operator will not forget to add the preservative. After the urine to be tested is added to the sampling tube, the preservative begins to be released and dispersed immediately, ensuring the effect of adding the preservative to the liquid to be tested in time.

[0047] At the same time, from bottom to top, the corresponding parts of the second cavity are connected with the first cavity; as the urine liquid level in the sampling tube changes, the solid preservative at the corresponding urine liquid level in the second cavity is automatically released and scattered, thereby ensuring that the quality of the preservative in the urine is roughly uniform, which is further conducive to ensuring the accuracy of the test results.

[0048] Example 2

[0049] Reference Figure 3 This embodiment provides a sampling tube with adaptive preservative release, which is different from Embodiment 1 in that: on the inner side of the tube body 1, starting from the bottom of the tube body 1, a group of partition components 3 protruding from the inner wall of the tube body 1 are formed along a spiral ascending direction on the inner wall of the tube body 1; the partition component 3 includes two parallel and oppositely arranged partition protrusions 31; the groove area formed between the two partition protrusions 31 in the same group is the second cavity 7.

[0050] Example 3

[0051] Reference Figure 4This embodiment provides a sampling tube with adaptive preservative release, which is different from Embodiment 1 in that: on the inner side of the tube body 1, starting from the bottom of the tube body 1, five groups of partition components 3 protruding from the inner wall of the tube body 1 are formed along the circumferential direction of the inner wall of the tube body 1; the five groups of partition components 3 are evenly distributed along the height direction of the inner wall of the tube body 1; the partition components 3 include two parallel and oppositely arranged partition protrusions 31; the groove area formed between the two partition protrusions 31 in the same group is the second cavity 7.

[0052] In this embodiment, since there is a certain height difference between adjacent partition components 3, the quality of the preservative dispersed therein will fluctuate to a certain extent as the urine liquid level changes. The influence on the fluctuation of the quality of the preservative in urine can be reduced by increasing the number of partition components 3 and reducing the distance between adjacent partition components 2. On the other hand, if the quality of the preservative has no effect on the test results, the sampling tube is fully applicable when the adjacent partition components 3 in this embodiment have a certain distance.

[0053] In this embodiment, when the partition components 3 are formed along the circumferential direction of the tube body 1 itself, the bottom of the second cavity 7 refers to the groove-shaped area formed by the lowest group of partition components 3 in the tube body 1.

[0054] Example 4

[0055] Reference Figure 5~Figure 6 The present embodiment provides a sampling tube for adaptively releasing preservatives, which includes a tube body 1 and a cover 2. The tube body 1 and the cover 2 are mostly made of plastic (such as PE, PP, PVC, etc.) by injection molding, which is low in cost and corrosion-resistant. The top of the tube body 1 is open and transparent; the cover 2 covers the open top of the tube body 1.

[0056] On the inner side of the tube body 1, starting from the bottom of the tube body 1, a groove 4 is formed on the inner wall of the tube body 1 along its own height direction; the groove area formed by the groove area of ​​the groove 4 is the second cavity 7; the area in the tube body 1 except the second cavity 7 is the first cavity 6; the first cavity 6 and the second cavity 7 are connected.

[0057] A solid preservative is laid in the second cavity 7; the solid preservative may be thymol (thymol) or the like. In specific operation, isopropyl alcohol or the like may be used as a solvent to prepare a thymol solution with a mass concentration of 10%, and then the thymol solution is introduced into the second cavity 7, and then the solvent is quickly air-dried to remove the solvent, and the remaining thymol adheres to the inner wall of the second cavity 7 to obtain the solid preservative.

[0058] In this embodiment, in order to ensure the accuracy of the internal volume of the tube body 1, when forming the scale on the outer wall of the tube body 1 along its own height direction, it is necessary to calculate the increased volume of the groove 4 and remove the volume occupied by the solid preservative.

[0059] In this embodiment, the length of the groove 4 can be set according to the requirements. For example, along the height direction of the tube body 1, the lower end of the groove 4 starts from the bottom of the first cavity 6 (i.e., the connection between the inner side wall and the inner bottom wall), and the upper end of the groove 4 ends at the top of the first cavity 6 (i.e., the open end). For another example, along the height direction of the tube body 1, the lower end of the groove 4 starts from the bottom of the first cavity 6 (i.e., the connection between the inner side wall and the inner bottom wall), and the upper end of the groove 4 ends at a position 5 to 10 mm away from the top of the first cavity 6 (i.e., the open end).

[0060] When urine is collected using the sampling tube in this embodiment, after the collected urine to be tested is added into the first cavity 6, since the first cavity 6 and the second cavity 7 are interconnected, the solid preservative is quickly and automatically released and dispersed after contacting the urine.

[0061] Compared with the traditional method of adding preservatives after sampling, the sampling tube of this embodiment has the preservative placed in the sampling tube before adding the urine to be tested, so the operator will not forget to add the preservative. After the urine to be tested is added to the sampling tube, the preservative begins to be released and dispersed immediately, ensuring the effect of adding the preservative to the liquid to be tested in time.

[0062] At the same time, from bottom to top, the corresponding parts of the second cavity are connected with the first cavity; as the urine liquid level in the sampling tube changes, the solid preservative at the corresponding urine liquid level in the second cavity is automatically released and scattered, thereby ensuring that the quality of the preservative in the urine is roughly uniform, which is further conducive to ensuring the accuracy of the test results.

[0063] Example 5

[0064] Reference Figure 7 The present embodiment provides a sampling tube for adaptively releasing preservatives, which is different from the embodiment 4 in that: on the inner side of the tube body 1, starting from the bottom of the tube body 1, a groove 4 is formed on the inner wall of the tube body 1 along a spiral ascending direction; the groove area formed by the groove area of ​​the groove 4 is the second cavity 7; the area in the tube body 1 except the second cavity 7 is the first cavity 6; the first cavity 6 and the second cavity 7 are connected.

[0065] Example 6

[0066] Reference Figure 8The present embodiment provides a sampling tube for adaptively releasing preservatives, which is different from the embodiment 4 in that: on the inner side of the tube body 1, starting from the bottom of the tube body 1, five grooves 4 are formed on the inner wall of the tube body 1 along its own circumferential direction; along the height direction of the inner wall of the tube body 1, the distance between each groove 4 is the same; the groove area formed by the groove area of ​​the groove 4 is the second cavity 7; the area in the tube body 1 except the second cavity 7 is the first cavity 6; the first cavity 6 and the second cavity 7 are connected.

[0067] In this embodiment, since there is a certain height difference between adjacent grooves 4, the quality of the preservative dispersed therein will fluctuate to a certain extent as the urine liquid level changes. The influence of the fluctuation of the quality of the preservative in urine can be reduced by increasing the number of grooves 4 and reducing the distance between two adjacent grooves 4. On the other hand, if the quality of the preservative has no effect on the test results, the sampling tube is completely applicable when the adjacent grooves 4 in this embodiment have a certain distance.

[0068] In this embodiment, when the groove 4 is formed along the circumferential direction of the tube body 1 itself, the bottom of the second cavity 7 refers to the groove area of ​​the lowest groove 4 in the tube body 1 .

[0069] Example 7

[0070] Reference Fig. 9 The present embodiment provides a sampling tube for adaptively releasing preservatives, which is different from the embodiment 1 in that: on the inner side of the tube body 1, starting from the bottom of the tube body 1, three groups of partition components 3 protruding from the inner wall of the tube body 1 are formed along the inner height direction of the tube body 1; the partition components 3 include two parallel and oppositely arranged partition protrusions 31; the three groups of partition components 3 are adjacent to each other, so that the adjacent partition components 3 share a common partition protrusion 31; the groove area formed between the two partition protrusions 31 in the same group is the second cavity 7; the area in the tube body 1 except the second cavity 7 is the first cavity 6; the first cavity 6 and the second cavity 7 are connected.

[0071] At the same time, a matching accommodating groove-shaped member 5 is arranged in each second cavity 7. The outer peripheral size of the accommodating groove-shaped member 5 is consistent with the size of the groove-shaped area formed between the two partition protrusions 31, and can be taken out from the two partition protrusions 31. The solid preservative is laid in the accommodating groove-shaped member 5, and then the accommodating groove-shaped member 5 and the solid preservative are laid in the second cavity 7 as a whole.

[0072] Specifically, when preparing the solid preservative, isopropanol or the like is used as a solvent to prepare a thymol solution with a mass concentration of 10%, and then the thymol solution is introduced into the receiving groove 5, and then the solvent is quickly air-dried to remove the solvent, which greatly improves the convenience of operation, is not affected by the narrow space in the tube body 1, and the solvent evaporates quickly. After the preservative is air-dried in the receiving groove 5, it is inserted into the middle area of ​​the partition protrusion 31, and then the detection can be carried out according to the process in Example 1.

[0073] Example 8

[0074] Reference Fig.10 The present embodiment provides a sampling tube for adaptively releasing preservatives, which is different from the embodiment 4 in that: on the inner side of the tube body 1, starting from the bottom of the tube body 1, three grooves 4 are formed on the inner wall of the tube body 1 along its own height direction; the three grooves 4 are evenly distributed along the circumferential direction of the inner wall of the tube body 1; the groove area formed by the groove area of ​​the groove 4 is the second cavity 7; the area in the tube body 1 except the second cavity 7 is the first cavity 6; the first cavity 6 and the second cavity 7 are connected.

[0075] At the same time, a matching receiving groove-shaped member 5 is arranged in each second receiving cavity 7. The outer peripheral size of the receiving groove-shaped member 5 is consistent with the size of the inner groove area of ​​the groove 4, and can be taken out from the two separation protrusions 31. The solid preservative is laid in the receiving groove-shaped member 5, and then the receiving groove-shaped member 5 and the solid preservative are laid in the second receiving cavity 7 as a whole.

[0076] Specifically, when preparing the solid preservative, isopropanol or the like is used as a solvent to prepare a thymol solution with a mass concentration of 10%, and then the thymol solution is introduced into the receiving groove 5, and then the solvent is quickly air-dried to remove the solvent, which greatly improves the convenience of operation, is not affected by the narrow space in the tube body 1, and the solvent evaporates quickly. After the preservative is air-dried in the receiving groove 5, it is inserted into the middle area of ​​the partition protrusion 31, and then the detection can be carried out according to the process in Example 4.

[0077] Example 9

[0078] Reference Fig.11 and Fig.12 The present embodiment provides a sampling tube for adaptively releasing preservatives, which is different from the embodiment 1 in that: on the inner side of the tube body 1, starting from the bottom of the tube body 1, a medicine containing tube 8 is arranged in the center position of the tube body 1 along its own height direction; the upper and lower ends of the medicine containing tube 8 are connected, and a notch 81 is opened on the tube wall of the medicine containing tube 8, and its outer wall is connected to the side wall of the tube body 1 by a bracket (not shown in the figure); the notch 81 starts from the lower end of the medicine containing tube 8 and ends at the upper end of the medicine containing tube 8; the internal area of ​​the medicine containing tube 8 is the second cavity 7.

[0079] Example 10

[0080] A common preservative in urine component analysis is thymol (thymol), which has a solubility in water of about 0.1 g / 100 mL (20°C). In order to further improve the dispersion effect of thymol when it contacts urine after being laid in the second cavity 7, a preset mass of thymol can be mixed with a preset volume of a volatile organic solvent (such as isopropanol, ethanol, chloroform, ether) to prepare a thymol solution, and then the thymol solution is introduced into the second cavity 7 in the tube body 1, and the volatile organic solvent is quickly dried (such as air drying, vacuum drying), and the remaining thymol adheres to the inner wall of the second cavity 7, and finally a sampling tube with adaptive release of preservatives as in the aforementioned embodiment is obtained.

[0081] On the one hand, since volatile organic solvents are used to dissolve thymol, the uniformity of thymol laid in the second cavity can be guaranteed in the end; on the other hand, the volatile organic solvents will cause the remaining thymol to have a large number of microporous structures in the interior during the rapid drying process, and the compactness and density of the powder itself will be reduced, so that it has a larger contact area when in contact with urine, thereby accelerating its release and dispersion process in urine and improving the dispersion effect.

[0082] When the specific thymol solution is introduced into the second cavity 7, the tube body 1 can be horizontally arranged in the sampling tube of the adaptive preservative release designed in Example 1, Example 4 and Example 9, and the opening area of ​​the second cavity 7 can be directed toward the thymol solution, and then the thymol solution can be introduced, and then the thymol solution can be quickly dried. For the sampling tube of the adaptive preservative release designed in Example 2, Example 3, Example 5 and Example 6, since the second cavity 7 has a certain curvature, the thymol solution can be added multiple times and the method of multiple rapid drying can be adopted; and each time the thymol solution is added, it is necessary to separate the thymol that has been dried last time to prevent it from dissolving.

Claims

1. A sampling tube for adaptively releasing preservatives, comprising a tube body (1) and a cover (2), characterized in that: The interior of the tube body (1) is a first cavity (6); starting from the bottom of the first cavity (6), an independent second cavity (7) is arranged in the first cavity (6); from bottom to top, corresponding parts of the second cavity (7) are all connected to the first cavity (6); and starting from the bottom of the second cavity (7), a solid preservative is laid in the second cavity (7).

2. The sampling tube for adaptively releasing preservatives according to claim 1, characterized in that: Starting from the bottom of the tube body (1), one or more grooves (4) are provided on the inner side wall of the tube body (1) along its own height direction; the inner area of ​​the groove (4) is the second cavity (7).

3. The sampling tube for adaptively releasing preservatives according to claim 1, characterized in that: Starting from the bottom of the tube body (1), one or more grooves (4) are provided on the inner wall of the tube body (1) in a spiral ascending direction; the inner area of ​​the groove (4) is the second cavity (7).

4. The sampling tube for adaptively releasing preservatives according to claim 1, characterized in that: Starting from the bottom of the tube body (1), a plurality of grooves (4) are provided on the inner wall of the tube body (1) along its circumferential direction; the inner area of ​​the grooves (4) is the second cavity (7).

5. The sampling tube for adaptively releasing preservatives according to claim 1, characterized in that: Starting from the bottom of the tube body (1), one or more partition components (3) are formed on the inner side wall of the tube body (1) along its own height direction and protrude from the inner side wall of the tube body (1); the partition component (3) includes two partition protrusions (31), and the area between the two partition protrusions (31) is the second cavity (7).

6. The sampling tube for adaptively releasing preservatives according to claim 1, characterized in that: Starting from the bottom of the tube body (1), one or more groups of partition components (3) are formed on the inner wall of the tube body (1) along a spiral ascending direction and protrude from the inner wall of the tube body (1); the partition component (3) comprises two partition protrusions (31), and the area between the two partition protrusions (31) is the second cavity (7).

7. The sampling tube for adaptively releasing preservatives according to claim 1, characterized in that: Starting from the bottom of the tube body (1), a plurality of partition components (3) are formed on the inner side wall of the tube body (1) in the circumferential direction thereof and protrude from the inner side wall of the tube body (1); the partition component (3) comprises two partition protrusions (31), and the area between the two partition protrusions (31) is the second cavity (7).

8. The sampling tube for adaptively releasing preservatives according to claim 1, characterized in that: Starting from the bottom of the tube body (1), one or more medicine containing tubes (8) are provided in the area of ​​the tube body (1) that is not in direct contact with the inner wall along its own height direction; the upper and lower ends of the medicine containing tube (8) are connected, and a notch (81) is provided on the tube wall of the medicine containing tube (8); the notch (81) starts from the lower end of the medicine containing tube (8) and ends at the upper end of the medicine containing tube (8); the internal area of ​​the medicine containing tube (8) is the second cavity (7).

9. The sampling tube for adaptively releasing preservative according to any one of claims 1 to 8, characterized in that: Graduations are formed on the outer wall of the tube body (1) along its height direction.

10. A method for improving the dispersion effect of a preservative, characterized in that: First, a preset mass of thymol is mixed with a preset volume of a volatile organic solvent to obtain a thymol solution, and then the thymol solution is introduced into the second cavity in the tube body, and the volatile organic solvent is quickly dried to remove the remaining thymol. The remaining thymol adheres to the inner wall of the second cavity, and finally a sampling tube for adaptively releasing preservatives as described in any one of claims 1 to 9 is obtained.

Citation Information

Patent Citations

  • Cup is left and taken in a disposable 24 hour urine examination from area is antiseptic

    CN206295365U

  • Special urine collecting barrel for quantitative test of urine protein

    CN213283067U

  • Spill-proof urine sampler

    CN221654369U

  • Sampling tube capable of self-adaptively releasing preservative

    CN223475068U

  • Tube having unitary blood coagulation activator and method for its preparation

    US5326535A