Liquid delivery simulation method, device and medium based on prostatitis animal model
Through the fluid delivery simulation method based on the animal model of prostatitis, the prostate is simulated to produce deformation and fluid flow under negative pressure, solving the complex problem of abnormal urination function in chronic prostatitis, and providing new methods and possible treatment methods to study the pathogenesis.
Patent Information
- Application Number
- CN202411475977.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-22
- Publication Date
- 2025-04-18
- Estimated Expiration
- 2044-10-22
AI Technical Summary
The symptoms of abnormal urination function caused by chronic prostatitis are complex and difficult to control, and the prior art is difficult to effectively detect and study the pathogenesis of prostatitis during urination.
The liquid delivery simulation method based on the animal model of prostatitis is used to identify bladder space information by scanning data, build liquid storage space and multiple liquid delivery spaces, generate multi-level liquid delivery models, and simulate the deformation of the prostate under negative pressure, record the liquid flow rate and intraflow field deformation, and generate prostate fluid delivery simulation results.
Simulation of the impact of prostatitis lesions on the urination process in animals is achieved, providing new ways to understand the possible mechanism of CP and helping to develop new treatment methods.
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Figure CN119361163B_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of prostate fluid delivery simulation, and in particular to a fluid delivery simulation method, device and medium based on a prostatitis animal model. Background Art
[0002] Chronic prostatitis (CP) is a common complex syndrome in male urological patients, with an incidence of approximately 2.0% to 16.0%, accounting for 25.0% to 33.0% of the total number of outpatients in urological departments [1]. CP has a long course and a variety of symptoms, among which abnormal urination function is one of the most common and difficult to treat main symptoms, which is manifested as frequent urination, urgency, dysuria, bifurcated urine, burning sensation in the urethra, weak and thin urine, and dysuria. The symptoms are sometimes mild and sometimes severe, and recur repeatedly. They are difficult to control with medication, which seriously affects the patient's mental health and quality of life. The etiology and pathogenesis of abnormal urination in CP are very complex, and no single mechanism can provide a satisfactory explanation for its many complex clinical manifestations. Therefore, it is urgent to detect the urination process during the onset of prostatitis, so as to study the pathological analysis of the role of urination in the induction of prostatitis and explore the possible mechanism of CP. Summary of the invention
[0003] In view of this, the purpose of the present application is to provide a liquid delivery simulation method, device and medium based on a prostatitis animal model.
[0004] According to the first aspect of the present application, a method for simulating liquid delivery based on a prostatitis animal model is provided, the method comprising:
[0005] According to the scan data of the prostatitis animal model, the spatial information of the bladder part in the prostatitis animal model is identified to construct a liquid storage space; the anatomical data corresponding to the prostatitis animal model is added with a random transformation factor to generate a plurality of irregular liquid delivery structures to construct a plurality of liquid delivery spaces, and a multi-level liquid delivery model is constructed based on the relative position relationship between the liquid storage space and the plurality of liquid delivery spaces in the scan data; and at the connection between the liquid storage space and the lowest liquid delivery space among the plurality of liquid delivery spaces, a prostatitis model is formed by a plurality of irregular spherical clusters of preset diameters, wherein the plurality of liquid delivery spaces are divided into a plurality of segments;
[0006] Meshing the internal flow field of the multi-stage liquid transport model to generate a liquid internal flow field; meshing the prostatitis model to respectively divide the fluid and solid in the prostatitis model to generate a prostatitis discrete model;
[0007] Constructing a bidirectional coupling data transmission between the prostatitis discrete model and the solid surface of the prostatitis model, and driving the solid region to move by applying a vertical negative pressure upward to the outer surface of the solid region, and transmitting the pressure to the fluid region through the boundary layer between the fluid and the solid, so that the fluid region is subjected to a force accumulation, so as to simulate the deformation of the prostate due to the negative pressure and the deformation of the internal flow field of the segmented internal flow field close to the prostatitis model in the liquid internal flow field under the deformation of the prostate;
[0008] From the direction of the plurality of liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space, according to the flow direction of the liquid in the multi-stage liquid delivery model, the liquid flow rate at the specified position in each of the segments of the multi-stage liquid delivery model is recorded in sequence, and according to the flow rate boundary condition, the liquid is transferred to the specified level of the previous segment of the segment in the prostatitis model, and the internal flow field motion simulation is performed on the previous segment of the segment in the multi-stage liquid delivery model, and the deformation of the prostatitis model is monitored to obtain the physical deformation data of the prostate, and the internal flow field motion of each segment is detected to obtain the internal flow field liquid data;
[0009] A prostate fluid transport simulation result is generated according to the fluid velocity at a designated level in each of the segments, the prostate physical deformation data and the internal flow field fluid data.
[0010] Optionally, constructing a multi-level liquid delivery model based on the relative position relationship between the liquid storage space and the plurality of liquid delivery spaces in the scanning data includes:
[0011] The scanning positions of the plurality of preset calibration points in the scanning data and the reference positions of the plurality of preset calibration points in the anatomical data are fitted with the actual set positions of the plurality of preset calibration points in the prostatitis animal model to obtain a position conversion relationship between the spatial position corresponding to the scanning data and the spatial position corresponding to the anatomical data;
[0012] Determine the spatial position information of the liquid storage space corresponding to the prostatitis animal model in the scan data, and determine the spatial position information of the plurality of liquid delivery spaces in the anatomical data;
[0013] Through the position conversion relationship, the spatial position information of the liquid storage space and the spatial position information of the multiple liquid delivery spaces are fitted in the three-dimensional simulation space to construct the multi-level liquid delivery model.
[0014] Optionally, the step of transferring the liquid to the designated level of the previous segment of the segment in the prostatitis model according to the flow rate boundary condition, simulating the internal flow field motion of the previous segment of the segment in the multi-stage liquid delivery model, and monitoring the deformation of the prostatitis model to obtain prostate physical deformation data and detecting the internal flow field motion of each segment to obtain internal flow field liquid data includes:
[0015] According to the flow velocity boundary condition, when the fluid reaches the designated level, internal flow field motion simulation is performed on the segments from the designated level to the previous designated level based on the multi-level liquid transport model;
[0016] The deformation of the prostatitis model during the internal flow field motion simulation is detected to obtain the prostate physical deformation data of the prostatitis model during the simulation process; and the liquid flow rate of the segment from the specified level to the previous specified level during the internal flow field motion simulation is detected to obtain the internal flow field liquid data of the segment.
[0017] Optionally, the deformation of the prostatitis model is detected during the internal flow field motion simulation process to obtain the prostate physical deformation data of the prostatitis model during the simulation process, including:
[0018] Before the internal flow field motion simulation process, the boundary contour of the prostatitis model is identified to obtain initial contour information corresponding to the boundary contour of the prostatitis model;
[0019] Performing real-time detection on the boundary contour of the prostatitis model during the internal flow field motion simulation process to obtain real-time deformation data corresponding to the boundary contour of the prostatitis model;
[0020] The prostate physical deformation data is generated according to a deformation area surrounded by a deformation position corresponding to the real-time deformation data and a deformation position corresponding to the initial contour information.
[0021] Optionally, generating the prostate physical deformation data according to a deformation area surrounded by a deformation position corresponding to the real-time deformation data and a deformation position corresponding to the initial contour information includes:
[0022] Determining the dynamic change characteristics of the deformation area during the internal flow field motion simulation;
[0023] According to the initial contour information and the dynamic change characteristics, the deformation characteristics of the prostatitis model during the internal flow field motion simulation process are generated; according to the deformation characteristics and the initial contour information, the motion state of the prostatitis model during the internal flow field motion simulation process is simulated to generate the prostate physical deformation data.
[0024] Optionally, generating a prostate liquid transport simulation result according to the fluid velocity at a specified level in each of the segments, the prostate physical deformation data and the internal flow field liquid data comprises:
[0025] According to whether the liquid flow rate and the liquid flow rate in the internal flow field liquid data are respectively within the set value range, a liquid transport simulation result is obtained;
[0026] The prostate liquid delivery simulation result is generated according to the liquid delivery simulation result.
[0027] According to a second aspect of the present application, a liquid delivery simulation device based on a prostatitis animal model is provided, the device comprising:
[0028] A construction module is used to identify the spatial information of the bladder part in the prostatitis animal model according to the scan data of the prostatitis animal model, and construct a liquid storage space; add a random transformation factor to the anatomical data corresponding to the prostatitis animal model to generate a plurality of irregular liquid delivery structures to construct a plurality of liquid delivery spaces, and construct a multi-level liquid delivery model based on the relative position relationship between the liquid storage space and the plurality of liquid delivery spaces in the scan data; and form a prostatitis model by clustering a plurality of irregular spheres of preset diameters at the connection between the liquid storage space and the lowest liquid delivery space among the plurality of liquid delivery spaces, wherein the plurality of liquid delivery spaces are divided into a plurality of segments;
[0029] A generation module is used to grid the internal flow field of the multi-stage liquid transport model to generate a liquid internal flow field; grid the prostatitis model to respectively divide the fluid and solid in the prostatitis model to generate a prostatitis discrete model;
[0030] A simulation module is used to construct a bidirectional coupling data transmission between the prostatitis discrete model and the solid surface of the prostatitis model, and to drive the solid area to move by applying a vertical negative pressure upward to the outer surface of the solid area, and to transfer the vertical negative pressure to the fluid area through the boundary layer between the fluid and the solid, so that the fluid area is subjected to force accumulation, so as to simulate the deformation of the prostate due to the negative pressure and the deformation of the internal flow field of the segmented internal flow field close to the prostatitis model in the liquid internal flow field under the deformation of the prostate;
[0031] A detection module, for recording the liquid flow rate at a specified position in each segment of the multi-stage liquid delivery model in sequence according to the flow direction of the liquid in the multi-stage liquid delivery model, from the multiple liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space, and according to the flow rate boundary condition, when transferring the liquid to the specified level of the previous segment of the segment in the prostatitis model, simulating the internal flow field motion of the previous segment of the segment in the multi-stage liquid delivery model, monitoring the deformation of the prostatitis model, obtaining prostate physical deformation data, and detecting the internal flow field motion of each segment to obtain internal flow field liquid data;
[0032] The execution module is used to generate a prostate fluid transport simulation result according to the fluid velocity at a specified level in each of the segments, the prostate physical deformation data and the internal flow field fluid data.
[0033] Optionally, the building block is further used to:
[0034] The scanning positions of the plurality of preset calibration points in the scanning data and the reference positions of the plurality of preset calibration points in the anatomical data are fitted with the actual set positions of the plurality of preset calibration points in the prostatitis animal model to obtain a position conversion relationship between the spatial position corresponding to the scanning data and the spatial position corresponding to the anatomical data;
[0035] Determine the spatial position information of the liquid storage space corresponding to the prostatitis animal model in the scan data, and determine the spatial position information of the plurality of liquid delivery spaces in the anatomical data;
[0036] Through the position conversion relationship, the spatial position information of the liquid storage space and the spatial position information of the multiple liquid delivery spaces are fitted in the three-dimensional simulation space to construct the multi-level liquid delivery model.
[0037] According to a second aspect of the present application, a computer-readable medium is provided, on which a computer program is stored, and when the program is executed by a processing device, the steps of any method described in the first aspect of the present disclosure are implemented.
[0038] According to a third aspect of the present application, there is provided an electronic device, including:
[0039] a storage device having at least one computer program stored thereon;
[0040] At least one processing device, used to execute the at least one computer program in the storage device to implement the steps of any one of the methods described in the first aspect of the present disclosure.
[0041] According to any one of the above aspects, the technical effect of the present application is:
[0042] According to the scanning data of the prostatitis animal model, the spatial information of the bladder part in the prostatitis animal model is identified to construct a liquid storage space; the anatomical data corresponding to the prostatitis animal model is added with random transformation factors to generate irregular multiple liquid delivery structures to construct multiple liquid delivery spaces, and a multi-level liquid delivery model is constructed based on the relative position relationship between the liquid storage space and the multiple liquid delivery spaces in the scanning data; and at the connection between the liquid storage space and the lowest liquid delivery space among the multiple liquid delivery spaces, a prostatitis model is formed by a plurality of irregular spherical clusters of preset diameters, wherein the multiple liquid delivery spaces are divided into a plurality of segments, and the internal flow field of the multi-level liquid delivery model is gridded to generate a liquid internal flow field; the prostatitis model is gridded to respectively divide the fluid and solid in the prostatitis model to generate a prostatitis discrete model, and a bidirectional coupling data transmission between the prostatitis discrete model and the solid surface of the prostatitis model is constructed, and a vertical negative pressure is applied vertically upward to the outer surface of the solid area to drive the solid to move. The body region moves, and is transferred to the fluid region through the boundary layer between the fluid and the solid, so that the fluid region is subjected to force and backlogged, so as to simulate the deformation of the prostate due to negative pressure and the deformation of the internal flow field of the segment close to the prostatitis model in the liquid internal flow field under the deformation of the prostate. From the multiple liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space, according to the flow direction of the liquid in the multi-stage liquid delivery model, the liquid flow rate at the specified position in each of the segments of the multi-stage liquid delivery model is recorded in sequence, and according to the flow rate boundary condition, the liquid is transferred to the specified level of the previous segment of the segment in the prostatitis model, and the internal flow field motion simulation is performed on the previous segment of the segment in the multi-stage liquid delivery model, and the deformation of the prostatitis model is monitored to obtain prostate physical deformation data and the internal flow field motion of each segment is detected to obtain internal flow field liquid data, and the prostate liquid delivery simulation result is generated according to the fluid velocity at the specified level in each segment, the prostate physical deformation data and the internal flow field liquid data. Therefore, based on the scanning data of the prostatitis animal model, the fluid transport of urine during daily exercise in prostatitis is simulated to identify the impact of prostatitis lesions on the animal's urination process, simulate the fluid transport process, and then study the possible occurrence mechanism of CP. BRIEF DESCRIPTION OF THE DRAWINGS
[0043] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.
[0044] Figure 1 is a flow chart of a liquid delivery simulation method based on a prostatitis animal model according to an embodiment of the present disclosure;
[0045] Figure 2 is a block diagram of a liquid delivery simulation device based on a prostatitis animal model according to an embodiment of the present disclosure;
[0046] Figure 3 A schematic diagram of the component structure of a liquid delivery simulation device based on a prostatitis animal model for implementing the above-mentioned liquid delivery simulation method based on a prostatitis animal model provided in an embodiment of the present application is shown. DETAILED DESCRIPTION
[0047] To make the purpose, technical scheme and advantages of the embodiment of the present application clearer, the technical scheme in the embodiment of the present application will be clearly and completely described below according to the drawings in the embodiment of the present application. It should be understood that the drawings in the present application only serve the purpose of explanation and description, and are not used to limit the scope of protection of the present application. In addition, it should be understood that the schematic drawings are not drawn in real proportion. The flowchart used in this application shows the operations implemented according to some embodiments of the embodiment of the present application. It should be understood that the operations of the flowchart can be implemented out of order, and the steps without logical context can be reversed in order or implemented simultaneously. In addition, those skilled in the art can add at least one other operation to the flowchart under the guidance of the content of the present application, or destroy at least one operation from the flowchart.
[0048] In addition, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. The components of the embodiments of the present application described and shown in the drawings here can be arranged and designed in various configurations. Therefore, the following detailed description of the embodiments of the present application provided in the drawings is not intended to limit the scope of the application claimed for protection, but merely represents the selected embodiments of the present application. According to the embodiments of the present application, all other embodiments obtained by those skilled in the art without making creative work correspond to the scope of protection of the present application.
[0049] Figure 1 FIG. 1 is a flow chart of a method for simulating liquid delivery based on a prostatitis animal model according to an embodiment of the present disclosure. Figure 1As shown, it should be understood that in other embodiments, the order of some steps in the liquid delivery simulation method based on the prostatitis animal model of this embodiment can be shared with each other according to actual needs, or some steps can be omitted or maintained. The detailed steps of the liquid delivery simulation method based on the prostatitis animal model include:
[0050] Step S11, identifying the spatial information of the bladder part in the prostatitis animal model according to the scanning data of the prostatitis animal model, and constructing a liquid storage space; adding random transformation factors to the anatomical data corresponding to the prostatitis animal model to generate multiple irregular liquid delivery structures to construct multiple liquid delivery spaces, and constructing a multi-level liquid delivery model based on the relative position relationship between the liquid storage space and the multiple liquid delivery spaces in the scanning data; and forming a prostatitis model by a plurality of irregular spherical clusters with preset diameters at the connection between the liquid storage space and the lowest liquid delivery space among the multiple liquid delivery spaces.
[0051] For example, in this embodiment, the liquid delivery space in the prostatitis animal model is graded and segmented to detect, and multiple liquid delivery spaces are divided into multiple segments to obtain the flow rate of the liquid at different positions, and the corresponding solid change characteristics. By scanning and dissecting the prostatitis animal model, the relevant structural tissues of the prostatitis animal model during the scanning and dissection process are identified to obtain the scanning data of the prostatitis animal model. Among them, the scanning data can be image data or CT image data. The bladder position in the prostatitis animal model in the scanning data is identified. It should be understood that the bladder position in the animal model is an animal organ for storing liquid. In the liquid delivery simulation analysis process of the prostatitis animal model, it is necessary to determine the position in the organ for storing liquid, and the storage position corresponds to the position for delivering liquid. The position of the delivery liquid includes the liquid input position and the liquid output position. Therefore, the bladder part in the prostatitis animal model is spatially identified to construct a liquid storage space. It should be noted that in this embodiment, the position of the bladder in the prostate animal model is identified by scanning data, and the spatial area wrapped by the bladder is identified to obtain the liquid storage space in the simulation process.
[0052] Considering the diversity of biological samples and the standardization of prostatitis animal models. It is necessary to randomly transform the anatomical data of the prostatitis animal model, add random transformation factors based on the anatomical data, and generate irregular liquid transport structures. The random transformation factors are the characteristic transformation ranges under multiple biological characteristic studies, including the value range of organ size, organ position range, organ shape range, etc. The anatomical data of the prostatitis animal model can be randomly transformed based on the random transformation factors to obtain irregular anatomical data, and then the position, length and width of multiple liquid transport structures in the transformed anatomical data are identified, and multiple liquid transport spaces are constructed after obtaining the identification data.
[0053] After the liquid storage space and multiple liquid delivery spaces are determined by the above method, multiple liquid delivery spaces are constructed on the liquid storage space based on the parent-child relationship of each space in the prostatitis animal model to generate a multi-level liquid delivery model. The parent-child relationship is determined based on the upstream and downstream relationship of the liquid flow in the prostatitis animal model. The multiple liquid delivery spaces located in the upper section of the liquid storage space and used to input liquid into the liquid storage space are the parent delivery spaces, that is, the ureter space from the bladder to the kidney is the parent delivery space; the liquid delivery space located in the lower section of the liquid storage space and transporting liquid downward from the liquid storage space is the child delivery space.
[0054] In this embodiment, it is necessary to simulate liquid delivery, which is used to study the effect of prostatitis corresponding to the prostatitis animal model on the liquid delivery process, which leads to the animal's urinary urgency, frequent urination, and dysuria when discharging liquid, and then reversely acts on prostatitis, leading to further lesions of the prostate. Therefore, in the liquid delivery simulation process, it is necessary to construct a prostatitis model at the corresponding position. For example, based on the conventional position of the prostate in the animal model, at the connection between the liquid storage space and the lowest liquid delivery space, a prostatitis model is formed by a plurality of irregular spherical clusters of preset diameters, and a plurality of irregular spherical clusters of preset diameters can be pre-stored in the database to construct the prostatitis model. It should be noted that in the construction process of the prostatitis model, it is necessary to construct the prostatitis model on the multi-level liquid delivery model space constructed above based on the position of the prostatitis model and the size of the prostatitis model. Thereby simulating the liquid delivery changes caused by the prostatitis symptoms during the liquid delivery process.
[0055] Optionally, in some embodiments, the above step of "constructing a multi-level liquid delivery model based on the relative position relationship between the liquid storage space and the plurality of liquid delivery spaces in the scanning data" includes:
[0056] The scanning positions of the multiple preset calibration points in the scanning data and the reference positions of the multiple preset calibration points in the anatomical data are fitted based on the actual set positions of the multiple preset calibration points in the prostatitis animal model to obtain a position conversion relationship between the spatial position corresponding to the scanning data and the spatial position corresponding to the anatomical data;
[0057] Determining spatial position information of a liquid storage space corresponding to a prostatitis animal model in the scan data, and determining spatial position information of a plurality of liquid transport spaces in the anatomical data;
[0058] Through the position conversion relationship, the spatial position information of the liquid storage space and the spatial position information of multiple liquid delivery spaces are fitted in the three-dimensional simulation space to construct a multi-level liquid delivery model.
[0059] For example, in this application, the spatial position information recorded between the scan data and the anatomical data is inconsistent, and correction and conversion are required during the conversion and combination process to avoid misalignment during the data combination process. In this embodiment, multiple preset calibration points are marked in the prostatitis animal model before data processing, and the scanning positions of the multiple preset calibration points in the scan data and the reference positions in the anatomical data are fitted based on different data processing methods. The scan position and the reference position are fitted based on the preset calibration points to obtain the position conversion relationship between the spatial position corresponding to the scan data and the spatial position corresponding to the anatomical data. Then, according to the position conversion relationship, the above-mentioned liquid delivery space and the above-mentioned multiple liquid delivery spaces are fitted and corrected, and the position space is converted into the digital space corresponding to the same data, thereby constructing a multi-level liquid delivery model. The fitting process is to correct the position relationship of each organ in the scan data, for example, to correct the position of the above-mentioned liquid delivery space in three-dimensional space. The positions of the above-mentioned multiple liquid delivery spaces in the three-dimensional space in the anatomical data are corrected, and the positions of the above-mentioned liquid delivery spaces in the three-dimensional space are converted to the three-dimensional space corresponding to the anatomical data, or the positions of the multiple liquid delivery spaces in the three-dimensional space are converted to the three-dimensional space corresponding to the scanning data, thereby achieving the unification between the liquid storage space and the multiple liquid delivery spaces, and ensuring the accuracy of the constructed multi-level liquid delivery model.
[0060] Step S12, meshing the internal flow field of the multi-stage liquid transport model to generate the liquid internal flow field; meshing the prostatitis model to respectively divide the fluid and solid in the prostatitis model to generate a discrete prostatitis model.
[0061] For example, in this embodiment, in order to perform liquid dynamics analysis, the entire liquid delivery model and the prostatitis model are meshed. For the liquid delivery model, since the prostate and the liquid delivery space are independent of each other, but the prostate wraps the delivery space corresponding to the liquid output position in the liquid delivery space, the lesion characteristics of the prostate will affect the flow rate, flow rate and reflux during the liquid discharge process. Therefore, in this embodiment, a discrete model of prostatitis is obtained through meshing, and the interaction relationship between prostatitis and the liquid discharge space during the liquid flow process is constructed through the discrete model of prostatitis.
[0062] Step S13, constructing a bidirectional coupling data transmission between the prostatitis discrete model and the solid surface of the prostatitis model, and driving the solid area to move by applying a vertical negative pressure upward to the outer surface of the solid area, and transmitting it to the fluid area through the boundary layer between the fluid and the solid, so that the fluid area is compressed by the force, so as to simulate the deformation of the prostate due to the negative pressure and the deformation of the segmented internal flow field close to the prostatitis model in the liquid internal flow field under the deformation of the prostate.
[0063] It should be noted that, through bidirectional coupling, the fluid pressure changes in the prostatitis discrete model can be fed back to the corresponding fixed part of the prostatitis model in real time. At the same time, the solid deformation of the prostatitis model will in turn affect the flow parameters of the liquid in the smooth flow. By gridding the prostatitis discrete model and constructing a bidirectional coupling between the prostatitis discrete model and the prostatitis model, the accuracy and authenticity of the simulation are guaranteed.
[0064] For example, in this embodiment, the bidirectional coupled data transmission between the prostatitis model and the prostatitis discrete model is used to simulate the force on the solid surface of the prostate during liquid transportation, and the real effect of the prostate on the liquid flow rate in the liquid transportation space. And the solid area is driven to move by applying a vertical negative pressure upward on the outer surface of the solid area, thereby simulating the normal movement process of the animal. Through the boundary layer between the fluid and the solid, the influence of the negative pressure movement is transmitted to the fluid area, simulating the negative pressure movement of the fluid area, resulting in the backlog of force in the fluid area, thereby simulating the deformation of the prostate when the prostate is deformed by negative pressure, and the deformation of the liquid transportation space of the internal flow field close to the corresponding internal flow field in the prostatitis model segment under the deformation of the prostate, thereby simulating the liquid transportation situation under this deformation based on the following method.
[0065] Step S14, from the direction of the liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space, according to the flow direction of the liquid in the multi-stage liquid delivery model, the liquid flow rate at the specified position in each segment of the multi-stage liquid delivery model is recorded in sequence, and according to the flow rate boundary condition, the liquid is transferred to the specified level of the previous segment of the segment in the prostatitis model, and the internal flow field motion of the previous segment of the segment in the multi-stage liquid delivery model is simulated, and the deformation of the prostatitis model is monitored to obtain the physical deformation data of the prostate and the internal flow field motion of each segment is detected to obtain the internal flow field liquid data.
[0066] For example, in this embodiment, from the direction of the multiple liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space, the multi-level liquid delivery model is segmented and detected according to the set classification distance and the organ wrapping distance. That is, in this embodiment, according to the above-mentioned parent-child relationship, the multi-level liquid delivery model is segmented, and the liquid flow rate at the specified position in each segment is recorded in sequence, and the flow of the liquid in the internal flow field in the multi-level liquid delivery model is simulated at the specified level according to the flow rate boundary condition, and the deformation of the prostatitis model is monitored during the liquid flow process to generate prostate physical deformation data and internal flow field liquid data, and the internal flow field liquid data is used to indicate the flow rate, flow rate and other information of the liquid at each specified level during the liquid flow process.
[0067] Optionally, in some embodiments, the above step of "transferring the liquid to the designated level of the previous segment of the segment in the prostatitis model according to the flow rate boundary condition, simulating the internal flow field motion of the previous segment of the segment in the multi-stage liquid delivery model, and monitoring the deformation of the prostatitis model to obtain prostate physical deformation data and detecting the internal flow field motion of each segment to obtain internal flow field liquid data" includes:
[0068] According to the flow velocity boundary condition, when the fluid reaches the designated level, internal flow field motion simulation is performed on the segments from the designated level to the previous designated level based on the multi-level liquid transport model;
[0069] The deformation of the prostatitis model during the internal flow field motion simulation is detected to obtain the prostate physical deformation data of the prostatitis model during the simulation process; and the liquid flow rate of the segment from the specified level to the previous specified level during the internal flow field motion simulation is detected to obtain the internal flow field liquid data of the segment.
[0070] For example, in this embodiment, according to the velocity boundary condition, the motion state of the liquid internal flow field in the segment from the specified level to the previous specified level in the multi-level liquid delivery model during the liquid delivery process is simulated. The velocity boundary condition is the area average velocity, and the cross-sectional velocity at the velocity inlet is a constant. The initial velocity of the liquid input into the multi-level liquid delivery model during the liquid simulation process and the liquid flow rate per minute are set based on the velocity boundary condition to simulate the actual liquid delivery process. The deformation of the prostatitis model during the internal flow field motion simulation is detected, and the deformation detection includes the shape, size, volume, displacement detection, etc. of the prostatitis model. The deformation of the prostatitis model at the segment from the specified level to the previous specified level during the internal flow field motion simulation, as well as the internal flow field liquid data in the segment, are obtained.
[0071] In some embodiments, the above step of "detecting the deformation of the prostatitis model during the internal flow field motion simulation to obtain the prostate physical deformation data of the prostatitis model during the simulation process" includes:
[0072] Before the internal flow field motion simulation process, the boundary contour of the prostatitis model is identified to obtain initial contour information corresponding to the boundary contour of the prostatitis model;
[0073] Performing real-time detection on the boundary contour of the prostatitis model during the internal flow field motion simulation process to obtain real-time deformation data corresponding to the boundary contour of the prostatitis model;
[0074] The prostate physical deformation data is generated according to a deformation area surrounded by a deformation position corresponding to the real-time deformation data and a deformation position corresponding to the initial contour information.
[0075] For example, in this embodiment, the deformation process of the prostatitis model during the internal flow field motion simulation is identified based on contour recognition. By tracking the contour of the prostatitis model, the real-time deformation data of the prostatitis model during the internal flow field motion simulation is obtained. The real-time deformation data is used to indicate the position change relationship of the corresponding contour of the prostatitis model. The deformation area enclosed by the deformed contour and the initial contour is detected in real time, and the physical deformation data of the prostate of the prostatitis model during the deformation process is characterized according to the deformation area.
[0076] Step S15, generating a prostate liquid transport simulation result according to the fluid velocity at a specified level in each of the segments, the prostate physical deformation data and the internal flow field liquid data.
[0077] For example, based on the prostate physical deformation data obtained by detecting the prostate deformation during the above-mentioned internal flow field simulation process, the specified basic fluid data is detected to obtain the fluid velocity, and the liquid parameters such as the flow rate and flow rate of the internal flow field liquid during the simulation process are detected to obtain the internal flow field liquid data. The above data are combined to obtain the prostate liquid transport simulation results during the internal flow field liquid simulation process.
[0078] Optionally, in some embodiments, the above step S15 includes:
[0079] According to whether the liquid flow rate and the liquid flow rate in the internal flow field liquid data are respectively within the set value range, a liquid transport simulation result is obtained;
[0080] The prostate liquid delivery simulation result is generated according to the liquid delivery simulation result.
[0081] For example, in this embodiment, the internal flow field liquid data is analyzed to determine whether the corresponding liquid flow velocity and liquid flow rate are within the set value range, so as to determine whether the deformation lesions of the prostatitis model in the above-mentioned internal flow field liquid simulation process affect the liquid delivery at the corresponding specified level, generate the liquid delivery simulation result, and based on the liquid delivery simulation result, perform deformation influence analysis to generate the prostate liquid delivery simulation result.
[0082] According to the scanning data of the prostatitis animal model, the spatial information of the bladder part in the prostatitis animal model is identified to construct a liquid storage space; the anatomical data corresponding to the prostatitis animal model is added with random transformation factors to generate irregular multiple liquid delivery structures to construct multiple liquid delivery spaces, and a multi-level liquid delivery model is constructed based on the relative position relationship between the liquid storage space and the multiple liquid delivery spaces in the scanning data; and at the connection between the liquid storage space and the lowest liquid delivery space among the multiple liquid delivery spaces, a prostatitis model is formed by a plurality of irregular spherical clusters of preset diameters, wherein the multiple liquid delivery spaces are divided into a plurality of segments, and the internal flow field of the multi-level liquid delivery model is gridded to generate a liquid internal flow field; the prostatitis model is gridded to respectively divide the fluid and solid in the prostatitis model to generate a prostatitis discrete model, and a bidirectional coupling data transmission between the prostatitis discrete model and the solid surface of the prostatitis model is constructed, and a vertical negative pressure is applied vertically upward to the outer surface of the solid area to drive the solid to move. The body region moves, and is transferred to the fluid region through the boundary layer between the fluid and the solid, so that the fluid region is subjected to force and backlogged, so as to simulate the deformation of the prostate due to negative pressure and the deformation of the internal flow field of the segment close to the prostatitis model in the liquid internal flow field under the deformation of the prostate. From the multiple liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space, according to the flow direction of the liquid in the multi-stage liquid delivery model, the liquid flow rate at the specified position in each of the segments of the multi-stage liquid delivery model is recorded in sequence, and according to the flow rate boundary condition, the liquid is transferred to the specified level of the previous segment of the segment in the prostatitis model, and the internal flow field motion simulation is performed on the previous segment of the segment in the multi-stage liquid delivery model, and the deformation of the prostatitis model is monitored to obtain prostate physical deformation data and the internal flow field motion of each segment is detected to obtain internal flow field liquid data, and the prostate liquid delivery simulation result is generated according to the fluid velocity at the specified level in each segment, the prostate physical deformation data and the internal flow field liquid data. Therefore, based on the scanning data of the prostatitis animal model, the fluid transport of urine during daily exercise in prostatitis is simulated to identify the impact of prostatitis lesions on the animal's urination process, simulate the fluid transport process, and then study the possible mechanism of CP.
[0083] Figure 2 FIG. 1 is a block diagram of a liquid delivery simulation device based on a prostatitis animal model according to an embodiment of the present disclosure. Figure 2 As shown, the device 100 includes:
[0084] The construction module 110 is used to identify the spatial information of the bladder part in the prostatitis animal model according to the scan data of the prostatitis animal model, and construct a liquid storage space; add a random transformation factor to the anatomical data corresponding to the prostatitis animal model to generate a plurality of irregular liquid delivery structures to construct a plurality of liquid delivery spaces, and construct a multi-level liquid delivery model based on the relative position relationship between the liquid storage space and the plurality of liquid delivery spaces in the scan data; and at the connection between the liquid storage space and the lowest liquid delivery space among the plurality of liquid delivery spaces, a plurality of irregular spherical clusters of preset diameters are used to form a prostatitis model, wherein the plurality of liquid delivery spaces are divided into a plurality of segments;
[0085] The generation module 120 is used to perform grid division on the internal flow field of the multi-stage liquid transport model to generate the liquid internal flow field; perform grid division on the prostatitis model to respectively divide the fluid and solid in the prostatitis model to generate a prostatitis discrete model;
[0086] The simulation module 130 is used to construct a bidirectional coupling data transmission between the discrete prostatitis model and the solid surface of the prostatitis model, and to drive the solid region to move by applying a vertical negative pressure upward to the outer surface of the solid region, and to transfer the vertical negative pressure to the fluid region through the boundary layer between the fluid and the solid, so that the fluid region is subjected to a force accumulation, so as to simulate the deformation of the prostate due to the negative pressure and the deformation of the internal flow field of the segmented internal flow field close to the prostatitis model in the liquid internal flow field under the deformation of the prostate;
[0087] The detection module 140 is used to sequentially record the liquid flow rate at a specified position in each segment of the multi-stage liquid delivery model in a direction from the multiple liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space according to the flow direction of the liquid in the multi-stage liquid delivery model, and according to the flow rate boundary condition, when transferring the liquid to the specified level of the previous segment of the segment in the prostatitis model, simulate the internal flow field motion of the previous segment of the segment in the multi-stage liquid delivery model, monitor the deformation of the prostatitis model, obtain prostate physical deformation data, and detect the internal flow field motion of each segment to obtain internal flow field liquid data;
[0088] The execution module 150 is used to generate a prostate fluid transport simulation result according to the fluid velocity at a specified level in each of the segments, the prostate physical deformation data and the internal flow field fluid data.
[0089] Optionally, the building block is further used to:
[0090] The scanning positions of the plurality of preset calibration points in the scanning data and the reference positions of the plurality of preset calibration points in the anatomical data are fitted with the actual set positions of the plurality of preset calibration points in the prostatitis animal model to obtain a position conversion relationship between the spatial position corresponding to the scanning data and the spatial position corresponding to the anatomical data;
[0091] Determine the spatial position information of the liquid storage space corresponding to the prostatitis animal model in the scan data, and determine the spatial position information of the plurality of liquid delivery spaces in the anatomical data;
[0092] Through the position conversion relationship, the spatial position information of the liquid storage space and the spatial position information of the multiple liquid delivery spaces are fitted in the three-dimensional simulation space to construct the multi-level liquid delivery model.
[0093] Optionally, the detection module 140 includes:
[0094] A simulation submodule, for simulating the internal flow field motion of the segment from the designated level to the previous designated level based on the multi-level liquid transport model when the fluid reaches the designated level according to the flow velocity boundary condition;
[0095] A generation submodule is used to detect the deformation of the prostatitis model during the internal flow field motion simulation to obtain the prostate physical deformation data of the prostatitis model during the simulation process and to detect the liquid flow rate of the segment from the specified level to the previous specified level during the internal flow field motion simulation to obtain the internal flow field liquid data of the segment.
[0096] Optionally, generate submodules, including:
[0097] A first generating unit is used to identify the boundary contour of the prostatitis model before the internal flow field motion simulation process to obtain initial contour information corresponding to the boundary contour of the prostatitis model;
[0098] A second generating unit is used to perform real-time detection on the boundary contour of the prostatitis model during the internal flow field motion simulation process to obtain real-time deformation data corresponding to the boundary contour of the prostatitis model;
[0099] The third generating unit is used to generate the prostate physical deformation data according to the deformation area surrounded by the deformation position corresponding to the real-time deformation data and the deformation position corresponding to the initial contour information.
[0100] Optionally, the third generating unit is used to
[0101] Determining the dynamic change characteristics of the deformation area during the internal flow field motion simulation;
[0102] According to the initial contour information and the dynamic change characteristics, the deformation characteristics of the prostatitis model during the internal flow field motion simulation process are generated; according to the deformation characteristics and the initial contour information, the motion state of the prostatitis model during the internal flow field motion simulation process is simulated to generate the prostate physical deformation data.
[0103] Optionally, the execution module 150 is configured to:
[0104] According to whether the liquid flow rate and the liquid flow rate in the internal flow field liquid data are respectively within the set value range, a liquid transport simulation result is obtained;
[0105] The prostate liquid delivery simulation result is generated according to the liquid delivery simulation result.
[0106] According to the scanning data of the prostatitis animal model, the spatial information of the bladder part in the prostatitis animal model is identified to construct a liquid storage space; the anatomical data corresponding to the prostatitis animal model is added with random transformation factors to generate irregular multiple liquid delivery structures to construct multiple liquid delivery spaces, and a multi-level liquid delivery model is constructed based on the relative position relationship between the liquid storage space and the multiple liquid delivery spaces in the scanning data; and at the connection between the liquid storage space and the lowest liquid delivery space among the multiple liquid delivery spaces, a prostatitis model is formed by a plurality of irregular spherical clusters of preset diameters, wherein the multiple liquid delivery spaces are divided into a plurality of segments, and the internal flow field of the multi-level liquid delivery model is gridded to generate a liquid internal flow field; the prostatitis model is gridded to respectively divide the fluid and solid in the prostatitis model to generate a prostatitis discrete model, and a bidirectional coupling data transmission between the prostatitis discrete model and the solid surface of the prostatitis model is constructed, and a vertical negative pressure is applied vertically upward to the outer surface of the solid area to drive the solid to move. The body region moves, and is transferred to the fluid region through the boundary layer between the fluid and the solid, so that the fluid region is subjected to force and backlogged, so as to simulate the deformation of the prostate due to negative pressure and the deformation of the internal flow field of the segment close to the prostatitis model in the liquid internal flow field under the deformation of the prostate. From the multiple liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space, according to the flow direction of the liquid in the multi-stage liquid delivery model, the liquid flow rate at the specified position in each of the segments of the multi-stage liquid delivery model is recorded in sequence, and according to the flow rate boundary condition, the liquid is transferred to the specified level of the previous segment of the segment in the prostatitis model, and the internal flow field motion simulation is performed on the previous segment of the segment in the multi-stage liquid delivery model, and the deformation of the prostatitis model is monitored to obtain prostate physical deformation data and the internal flow field motion of each segment is detected to obtain internal flow field liquid data, and the prostate liquid delivery simulation result is generated according to the fluid velocity at the specified level in each segment, the prostate physical deformation data and the internal flow field liquid data. Therefore, based on the scanning data of the prostatitis animal model, the fluid transport of urine during daily exercise in prostatitis is simulated to identify the impact of prostatitis lesions on the animal's urination process, simulate the fluid transport process, and then study the possible mechanism of CP.
[0107] Figure 3The liquid delivery simulation device 100 based on the prostatitis animal model shown includes: a processor 1001 and a memory 1003. Among them, the processor 1001 and the memory 1003 are connected, such as being connected through a bus 1002. Optionally, the liquid delivery simulation device 100 based on the prostatitis animal model may also include a transceiver 1004, which may be used for data interaction between the server and other servers, such as data transmission and / or data reception. It should be noted that in actual scheduling, the transceiver 1004 is not limited to one, and the structure of the liquid delivery simulation device 100 based on the prostatitis animal model does not constitute a limitation on the embodiments of the present application.
[0108] Processor 1001 may be a CPU (Central Processing Unit), a general-purpose processor, a DSP (Digital Signal Processor), an ASIC (Application Specific Integrated Circuit), an FPGA (Field Programmable Gate Array) or other programmable logic devices, transistor logic devices, hardware components or any combination thereof. It may implement or execute various exemplary logic blocks, modules and circuits described in conjunction with the disclosure of this application. Processor 1001 may also be a combination that implements computing functions, such as a combination of one or more microprocessors, a combination of a DSP and a microprocessor, etc.
[0109] The bus 1002 may include a path to transmit information between the above components. The bus 1002 may be a PCI (Peripheral Component Interconnect) bus or an EISA (Extended Industry Standard Architecture) bus. The bus 1002 may be divided into an address bus, a data bus, a control bus, etc. For ease of representation, Figure 3 Only one thick line is used in the diagram, but this does not mean that there is only one bus or only one type of bus.
[0110] The memory 1003 may be a ROM (Read Only Memory) or other types of static storage devices that can store static information and instructions, a RAM (Random Access Memory) or other types of dynamic storage devices that can store information and instructions, or an EEPROM (Electrically Erasable Programmable Read Only Memory), a CD-ROM (Compact Disc Read Only Memory) or other optical disk storage, optical disk storage (including compressed optical disk, laser disk, optical disk, digital versatile disk, Blu-ray disk, etc.), magnetic disk storage medium, other magnetic storage devices, or any other medium that can be used to carry or store program code and can be read by a computer, without limitation herein.
[0111] The memory 1003 is used to store program codes for executing the embodiments of the present application, and the execution is controlled by the processor 1001. The processor 1001 is used to execute the program codes stored in the memory 1003 to implement the steps shown in the above method embodiments.
[0112] An embodiment of the present application provides a computer-readable storage medium having program code stored thereon. When the program code is executed by a processor, the steps and corresponding contents of the aforementioned method embodiment can be implemented.
[0113] It should be understood that, although each operation step is indicated by arrows in the flowchart of the embodiment of the present application, the implementation order of these steps is not limited to the order indicated by the arrows. Unless there is a clear description in this article, in some implementation scenarios of the embodiment of the present application, the implementation steps in each flowchart can be performed in other orders based on demand. In addition, some or all of the steps in each flowchart may include multiple sub-steps or multiple stages according to the actual implementation scenario. Some or all of these sub-steps or stages can be executed at the same time, and each sub-step or stage in these sub-steps or stages can also be executed at different times respectively. In different scenarios at the execution time, the execution order of these sub-steps or stages can be flexibly configured based on demand, and the embodiment of the present application does not limit this.
[0114] The above is only an optional implementation method for some implementation scenarios of the present application. It should be pointed out that for ordinary technicians in this technical field, without departing from the technical concept of the scheme of the present application, other similar implementation methods based on the technical ideas of the present application are also within the protection scope of the embodiments of the present application.
Claims
1. A liquid delivery simulation method based on a prostatitis animal model, characterized in that: The method comprises: According to the scan data of the prostatitis animal model, the spatial information of the bladder part in the prostatitis animal model is identified to construct a liquid storage space; the anatomical data corresponding to the prostatitis animal model is added with a random transformation factor to generate a plurality of irregular liquid delivery structures to construct a plurality of liquid delivery spaces, and a multi-level liquid delivery model is constructed based on the relative position relationship between the liquid storage space and the plurality of liquid delivery spaces in the scan data; and at the connection between the liquid storage space and the lowest liquid delivery space among the plurality of liquid delivery spaces, a prostatitis model is formed by a plurality of irregular spherical clusters of preset diameters, wherein the plurality of liquid delivery spaces are divided into a plurality of segments, and the plurality of liquid delivery spaces include one or more parent delivery spaces and a plurality of child delivery spaces; Meshing the internal flow field of the multi-stage liquid transport model to generate a liquid internal flow field; meshing the prostatitis model to respectively divide the fluid and solid in the prostatitis model to generate a prostatitis discrete model; Constructing a bidirectional coupling data transmission between the prostatitis discrete model and the solid surface of the prostatitis model, and applying a vertical negative pressure upward to the outer surface of the solid area to drive the solid area to move, and transmitting it to the fluid area through the boundary layer between the fluid and the solid, so that the fluid area is subjected to force accumulation, so as to simulate the deformation of the prostate due to the negative pressure and the deformation of the internal flow field of the segmented internal flow field close to the prostatitis model in the liquid internal flow field under the deformation of the prostate; From the direction of the multiple liquid delivery spaces approaching the liquid storage space to the direction away from the liquid storage space, according to the flow direction of the liquid in the multi-stage liquid delivery model, the liquid flow rate at the specified position in each of the segments of the multi-stage liquid delivery model is recorded in sequence and segmented, and according to the flow rate boundary condition, when the liquid is transferred to the specified level of the previous segment of the segment in the prostatitis model, the previous segment of the segment in the multi-stage liquid delivery model is simulated for the internal flow field motion, and the deformation of the prostatitis model is monitored to obtain the physical deformation data of the prostate and the internal flow field motion of each segment is detected to obtain the internal flow field liquid data, wherein the direction from the approaching the liquid storage space to the direction away from the liquid storage space is the direction from the parent delivery space to the corresponding child delivery space; A prostate fluid transport simulation result is generated according to the fluid velocity at a designated level in each of the segments, the prostate physical deformation data and the internal flow field fluid data.
2. The liquid delivery simulation method based on the prostatitis animal model according to claim 1, characterized in that: The constructing of a multi-level liquid delivery model based on the relative position relationship between the liquid storage space and the plurality of liquid delivery spaces in the scanning data comprises: The scanning positions of the plurality of preset calibration points in the scanning data and the reference positions of the plurality of preset calibration points in the anatomical data are fitted with the actual set positions of the plurality of preset calibration points in the prostatitis animal model to obtain a position conversion relationship between the spatial position corresponding to the scanning data and the spatial position corresponding to the anatomical data; Determine the spatial position information of the liquid storage space corresponding to the prostatitis animal model in the scan data, and determine the spatial position information of the plurality of liquid delivery spaces in the anatomical data; Through the position conversion relationship, the spatial position information of the liquid storage space and the spatial position information of the multiple liquid delivery spaces are fitted in the three-dimensional simulation space to construct the multi-level liquid delivery model.
3. The liquid delivery simulation method based on the prostatitis animal model according to claim 1, characterized in that: The method comprises: transferring the liquid to the designated level of the previous segment of the segment in the prostatitis model according to the flow rate boundary condition, simulating the internal flow field motion of the previous segment of the segment in the multi-stage liquid delivery model, monitoring the deformation of the prostatitis model, obtaining the physical deformation data of the prostate, and detecting the internal flow field motion of each segment to obtain the internal flow field liquid data, including: According to the flow velocity boundary condition, when the fluid reaches the designated level, internal flow field motion simulation is performed on the segments from the designated level to the previous designated level based on the multi-level liquid transport model; The deformation of the prostatitis model during the internal flow field motion simulation is detected to obtain the prostate physical deformation data of the prostatitis model during the simulation process; and the liquid flow rate of the segment from the specified level to the previous specified level during the internal flow field motion simulation is detected to obtain the internal flow field liquid data of the segment.
4. The liquid delivery simulation method based on the prostatitis animal model according to claim 3, characterized in that: The method of detecting the deformation of the prostatitis model during the internal flow field motion simulation to obtain the prostate physical deformation data of the prostatitis model during the simulation process includes: Before the internal flow field motion simulation process, the boundary contour of the prostatitis model is identified to obtain initial contour information corresponding to the boundary contour of the prostatitis model; Performing real-time detection on the boundary contour of the prostatitis model during the internal flow field motion simulation process to obtain real-time deformation data corresponding to the boundary contour of the prostatitis model; The prostate physical deformation data is generated according to a deformation area surrounded by a deformation position corresponding to the real-time deformation data and a deformation position corresponding to the initial contour information.
5. The method for simulating liquid delivery based on a prostatitis animal model according to claim 4, characterized in that: The generating the prostate physical deformation data according to the deformation area surrounded by the deformation position corresponding to the real-time deformation data and the deformation position corresponding to the initial contour information comprises: Determining the dynamic change characteristics of the deformation area during the internal flow field motion simulation; According to the initial contour information and the dynamic change characteristics, the deformation characteristics of the prostatitis model during the internal flow field motion simulation process are generated; according to the deformation characteristics and the initial contour information, the motion state of the prostatitis model during the internal flow field motion simulation process is simulated to generate the prostate physical deformation data.
6. The method for simulating liquid delivery based on a prostatitis animal model according to any one of claims 1 to 5, characterized in that: The generating of the prostate liquid transport simulation result according to the fluid velocity at the designated level in each of the segments, the prostate physical deformation data and the internal flow field liquid data comprises: According to whether the liquid flow rate and the liquid flow rate in the internal flow field liquid data are respectively within the set value range, a liquid transport simulation result is obtained; The prostate liquid delivery simulation result is generated according to the liquid delivery simulation result.
7. A liquid delivery simulation device based on a prostatitis animal model, characterized in that: The device comprises: A construction module is used to identify the spatial information of the bladder part in the prostatitis animal model according to the scan data of the prostatitis animal model, and construct a liquid storage space; add a random transformation factor to the anatomical data corresponding to the prostatitis animal model to generate multiple irregular liquid delivery structures to construct multiple liquid delivery spaces, and construct a multi-level liquid delivery model based on the relative position relationship between the liquid storage space and the multiple liquid delivery spaces in the scan data; and at the connection between the liquid storage space and the lowest liquid delivery space among the multiple liquid delivery spaces, a prostatitis model is formed by a plurality of irregular spherical clusters of preset diameters, wherein the multiple liquid delivery spaces are divided into multiple segments, and the multiple liquid delivery spaces include one or more parent delivery spaces and multiple child delivery spaces; A generation module is used to grid the internal flow field of the multi-stage liquid transport model to generate a liquid internal flow field; grid the prostatitis model to respectively divide the fluid and solid in the prostatitis model to generate a prostatitis discrete model; A simulation module is used to construct a bidirectional coupling data transmission between the prostatitis discrete model and the solid surface of the prostatitis model, and to drive the solid area to move by applying a vertical negative pressure upward to the outer surface of the solid area, and to transfer the vertical negative pressure to the fluid area through the boundary layer between the fluid and the solid, so that the fluid area is subjected to force accumulation, so as to simulate the deformation of the prostate due to the negative pressure and the deformation of the internal flow field of the segmented internal flow field close to the prostatitis model in the liquid internal flow field under the deformation of the prostate; A detection module, for recording the liquid flow rate at a specified position in each segment of the multi-stage liquid delivery model in sequence according to the flow direction of the liquid in the multi-stage liquid delivery model, from the multiple liquid delivery spaces close to the liquid storage space to the direction away from the liquid storage space, and according to the flow rate boundary condition, when transferring the liquid to the specified level of the previous segment of the segment in the prostatitis model, simulating the internal flow field motion of the previous segment of the segment in the multi-stage liquid delivery model, and monitoring the deformation of the prostatitis model to obtain prostate physical deformation data and detecting the internal flow field motion of each segment to obtain internal flow field liquid data, wherein the direction from close to the liquid storage space to away from the liquid storage space is the direction from the parent delivery space to the corresponding child delivery space; The execution module is used to generate a prostate fluid transport simulation result according to the fluid velocity at a specified level in each of the segments, the prostate physical deformation data and the internal flow field fluid data.
8. The liquid delivery simulation device based on the prostatitis animal model according to claim 7, characterized in that: The building blocks are also used to: The scanning positions of the plurality of preset calibration points in the scanning data and the reference positions of the plurality of preset calibration points in the anatomical data are fitted with the actual set positions of the plurality of preset calibration points in the prostatitis animal model to obtain a position conversion relationship between the spatial position corresponding to the scanning data and the spatial position corresponding to the anatomical data; Determine the spatial position information of the liquid storage space corresponding to the prostatitis animal model in the scan data, and determine the spatial position information of the plurality of liquid delivery spaces in the anatomical data; Through the position conversion relationship, the spatial position information of the liquid storage space and the spatial position information of the multiple liquid delivery spaces are fitted in the three-dimensional simulation space to construct the multi-level liquid delivery model.
9. A computer readable medium having a computer program stored thereon, characterized in that: When the program is executed by a processing device, the steps of the method described in any one of claims 1 to 7 are implemented.
10. An electronic device, characterized in that: include: a storage device having at least one computer program stored thereon; At least one processing device, configured to execute the at least one computer program in the storage device to implement the steps of the method according to any one of claims 1 to 7.
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