Patents
Literature
Patsnap Copilot is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Patsnap Copilot

202 results about "Injections sites" patented technology

Diagnostic procedures using direct injection of gaseous hyperpolarized 129Xe and associated systems and products

A method of screening for pulmonary embolism uses gaseous phase polarized <129>Xe which is injected directly into the vasculature of a subject. The gaseous <129>Xe can be delivered in a controlled manner such that the gas substantially dissolves into the vasculature proximate to the injection site. Alternatively, the gas can be injected such that it remains as a gas in the bloodstream for a period of time (such as about 8-29 seconds). The injectable formulation of polarized <129>Xe gas is presented in small quantities of (preferably isotopically enriched) hyperpolarized <129>Xe and can provide high-quality vasculature MRI images or NMR spectroscopic signals with clinically useful signal resolution or intensity. One method injects the polarized <129>Xe as a gas into a vein and also directs another quantity of polarized gas into the subject via inhalation. In this embodiment, the perfusion uptake allows arterial signal information and the injection (venous side) allows venous signal information. The dual delivery is used to generate a combined introduction path with a more complete image signal of both the arterial and venous side of the pulmonary vasculature. In this NMR imaging method, the pulmonary embolism screening method can use the same NMR chest coil for the excitation and detection of the <129>Xe signals. The direct injection of small quantities of gas at particular sites along the vasculature targets specific target regions to provide increased signal intensity NMR images. The disclosure also includes related methods directed to other diagnostic vasculature regions physiological and conditions. Associated delivery and dispensing systems and methods, containers, and quantitative formulations of the polarized gas are also described.
Owner:UNIV OF VIRGINIA ALUMNI PATENTS FOUND +1

Auto-injector

The invention refers to an auto-injector (1) for administering a dose of a liquid medicament (M), comprising a tubular chassis (2) telescopable in a tubular case (12); a carrier subassembly comprising a tubular carrier (7) slidably arranged relative to the chassis (2) inside the case (12), the carrier (7) adapted to contain a syringe (3) with a hollow injection needle (4), a drive spring (8) and a plunger (9) for forwarding load of the drive spring (8) to a stopper (6) of the syringe (3), wherein the syringe (3) is lockable for joint axial translation with the carrier (7); a control spring (19) arranged around the carrier (7) for translating the carrier (7) in a proximal direction (P) for insertion of the needle (4) through the chassis (2) into an injection site, wherein the control spring (19) is arranged to bias the case (12) against the chassis (2) in a distal direction (D), so as to extend the chassis (2) out of a proximal end (P) of the case (12), wherein an insertion depth of the needle (4) is defined by the carrier (7) abutting the chassis (2) in a predefined position, wherein the case (12) is arranged to release or allow release of the control spring (19) for needle insertion on translation of the case (12) in the proximal direction (P) relative to the chassis (2) against the bias into an advanced position.
Owner:SANOFI AVENTIS DEUT GMBH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products