Insecticidal composition containing benzoylureas

Abstract

The invention belongs to the field of pesticides, and relates to an insecticidal composition containing benzoylurea. Effective components of the insecticidal composition comprise an active component A and an active component B, the active component A is a compound represented by a formula (I), the active component B is a benzoylurea compound, and a mass ratio of the active component A to the active component B is 1: 50-56: 1. The insecticidal composition has the advantages of synergism, resistance delay and the like, and is used for preventing and treating resistant pests.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticides and insecticides, and particularly relates to an insecticide composition containing benzoyl ureas. Background Art

[0002] Benzoylurea insecticides are a type of chitin synthesis inhibitor based on benzoylurea compounds. They are insect growth regulators that inhibit the activity of chitin synthase in target pests, affecting chitin synthesis in the pest cuticle, thereby affecting the pests' feeding, molting and pupation, and ultimately leading to the death of the pests. This type of insecticide has the advantages of high selectivity and easy decomposition in the environment. It has good control effects on Lepidoptera and Diptera pests, but its rapid effect is poor and it is easy to develop resistance.

[0003] In the process of agricultural production, the frequent and unreasonable use of pesticides has led to the continuous enhancement of the resistance of harmful insects, which has caused more serious damage to crops and made prevention and control more difficult. In order to promote the sustainable development of benzoylurea pesticide products and solve the scientific problems they face, this study mixed the compound of formula (I) with benzoylurea pesticides to achieve rapid control of different pests, expand the control spectrum, improve the efficacy of the pesticide, and reduce the generation of pest resistance. Summary of the invention

[0004] The invention aims to provide an insecticide composition containing benzoylureas which has synergistic effect, reduces resistance and has low use cost.

[0005] To achieve the above object, the technical solution adopted by the present invention is: an insecticide composition containing benzoylurea, comprising active ingredient A and active ingredient B, wherein the active ingredient A is a compound of formula (I) with the following structure:

[0006] The active ingredient B is a benzoylurea compound;

[0007] Further, the benzoylurea compounds include lufenuron, diflubenzuron, diflubenzuron, bistrifluanuron, chlorfluazuron, fluazifop, flufenoxuron, flubendiamide, flufenoxuron, flubendiamide, flufluanidone, flufenoxuron ...;

[0008] Furthermore, the benzoylurea compound is diflubenzuron, thiofluanidone, and hexafluanidone;

[0009] Furthermore, the mass ratio between the active ingredient A and the active ingredient B is 1:50 to 56:1;

[0010] Furthermore, the mass ratio between the active ingredient A and the active ingredient B is 1:35 to 35:1;

[0011] Furthermore, the mass ratio of the compound of formula (I) to lufenuron is 1:35 to 35:1, such as 1:35, 1:18, 1:9, 2:5, 3:4, 9:1, 18:1, 35:1 or any value between the above values;

[0012] Furthermore, the mass ratio of the compound of formula (I) to lufenuron is 1:18 to 18:1.

[0013] Furthermore, the mass ratio of the compound of formula (I) to lufenuron is 1:18, 1:9, 2:5, 3:4, 9:1, 18:1;

[0014] Furthermore, the mass ratio of the compound of formula (I) to diflubenzuron is 1:32 to 27:1, such as 1:50, 1:32, 1:7, 4:1, 4:5, 12:1, 27:1 or any value between the above values;

[0015] Furthermore, the mass ratio of the compound of formula (I) to diflubenzuron is 1:7 to 27:1.

[0016] Furthermore, the mass ratio of the compound of formula (I) to diflubenzuron is 1:7, 4:1, 4:5, 12:1, 27:1;

[0017] The mass ratio of the compound of formula (I) to diflubenzuron is 1:27 to 27:1; such as 1:27, 1:14, 1:6, 2:3, 6:1, 14:1, 27:1, 56:1 or any value between the above values;

[0018] Furthermore, the mass ratio of the compound of formula (I) to diflubenzuron is 1:14 to 27:1;

[0019] Furthermore, the mass ratio of the compound of formula (I) to diflubenzuron is 1:14, 1:6, 2:3, 6:1, 14:1, 27:1;

[0020] Furthermore, based on the total mass of the insecticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 0.5% to 90%;

[0021] Furthermore, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 1% to 85%;

[0022] Furthermore, the insecticide composition includes agriculturally acceptable auxiliary ingredients in addition to the active ingredients, and the auxiliary ingredients are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists or carriers;

[0023] Furthermore, the acaricide composition further comprises an adjuvant, which is selected from one or more of a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a solvent, a preservative, a stabilizer, a synergist and a carrier;

[0024] Further, the wetting agent is selected from one or more of alkylbenzene sulfonate, alkylnaphthalene sulfonate, lignin sulfonate, sodium dodecyl sulfate, sodium dioctyl succinate sulfonate, alpha olefin sulfonate, alkylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, alkylphenol ethoxylate, fatty alcohol ethoxylate, fatty alcohol polyoxyethylene ether sodium sulfate, silkworm feces, saponin powder, soapberry powder, SOPA, detergent, emulsifier 2000 series and wetting penetrant F; and / or

[0025] Further, the dispersant is selected from one or more of lignin sulfonate, alkylnaphthalene sulfonate formaldehyde condensate, naphthalene sulfonate, tristyrylphenol ethoxylate phosphate, fatty alcohol ethoxylate, alkylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether methyl ether condensate sulfate, fatty amine polyoxyethylene ether, glycerol fatty acid ester polyoxyethylene ether, polycarboxylates, polyacrylic acids, phosphates, EO-PO block copolymers and EO-PO graft copolymers; and / or

[0026] Further, the emulsifier is selected from one or more of calcium dodecylbenzene sulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, phenylethylphenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether and alkylphenol ether phosphate; and / or

[0027] Furthermore, the thickener is selected from one or more of xanthan gum, organic bentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose and white carbon black; and / or

[0028] Furthermore, the disintegrant is selected from one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid and tartaric acid; and / or

[0029] Furthermore, the antifreeze agent is selected from one or more of alcohols, alcohol ethers, chlorinated hydrocarbons and inorganic salts; and / or

[0030] Furthermore, the defoaming agent is selected from C 10 -C 20 Saturated fatty acid compounds, silicone oil, silicone compounds, C8-C 10 One or more of fatty alcohols; and / or

[0031] Further, the solvent is selected from one or more of benzene, toluene, xylene, durene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethylformamide, cyclohexanone, alkylene carbonate, diesel, solvent oil, vegetable oil, vegetable oil derivatives and water; and / or

[0032] Further, the preservative is selected from one or more of propionic acid, sodium propionate, sorbic acid, sodium sorbate, potassium sorbate, benzoic acid, sodium benzoate, sodium p-hydroxybenzoate, methyl p-hydroxybenzoate, kasone and 1,2-benzisothiazolin-3-one; and / or

[0033] Further, the stabilizer is selected from one or more of disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-cresol, triethanolamine oleate, epoxidized vegetable oil, kaolin, bentonite, attapulgite, white carbon black, talc, montmorillonite and starch; and / or

[0034] Furthermore, the synergist is selected from synergist phosphine and piperonyl ether; and / or

[0035] Furthermore, the carrier is selected from one or more of ammonium salts, ground natural minerals, ground artificial minerals, silicates, resins, waxes, solid fertilizers, water, organic solvents, mineral oils, vegetable oils and vegetable oil derivatives.

[0036] Furthermore, the insecticide composition can be prepared into an agriculturally acceptable formulation, and the formulation is selected from a solid formulation and / or a liquid formulation;

[0037] Furthermore, the solid preparation includes powders, granules, pellets, tablets, strips, wettable powders, oil-dispersible powders, emulsion powders, water-dispersible granules, emulsion granules, water-dispersible tablets, soluble powders, soluble tablets or soluble granules;

[0038] Further, the liquid preparation includes a soluble solution, a soluble gel, an oil, a film-spreading oil, an emulsifiable concentrate, a latex, a dispersible liquid, an ointment, an aqueous emulsion, an oil emulsion, a microemulsion, a fat, a suspension, a microcapsule suspension, an oil suspension, a dispersible oil suspension, a suspoemulsion, a microcapsule suspension-suspension, a microcapsule suspension-water emulsion or a microcapsule suspension-suspoemulsion;

[0039] Furthermore, the solid preparation is selected from wettable powders and water dispersible granules; the liquid preparation is selected from emulsifiable concentrates, aqueous emulsions, microemulsions, suspensions, suspoemulsions, and dispersible oil suspensions;

[0040] Furthermore, the solid preparation is selected from wettable powders and water dispersible granules; the liquid preparation is selected from emulsifiable concentrates and suspensions;

[0041] Application of the insecticide composition of the present invention in preventing and controlling agricultural and forestry pests and sanitary pests;

[0042] The insecticide composition of the present invention can be used to control pests on fruit trees, vegetables, ornamental plants, tea, cotton, and cereal crops;

[0043] Furthermore, the agricultural and forestry pests and sanitary pests are Lepidoptera pests;

[0044] Further, the Lepidoptera pests include: Adoxophyes spp., Adoxophyes orana, Agrotis spp. (cutworms), Agrotis ipsilon (black cutworm), Alabamaargillacea (cotton leafworm), Amorbia cuneana, Amyelosis transitella (navel orangeworm), Anacamptodes defectaria, Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia g emma talis, Archips argyrospila (fruittreeleafroller), Archips rose leafroller, rosana(rose leaf roller), Argyrotaenia spp.(tortricid moths), Argyrotaenia citrana(orange tortrix), Autographa gamma, Bonagota cranaodes, Borbo cinnara(rice leaf folder), Bucculatrix thurberiella(cotton leaf perforator), Caloptilia spp.(leaf miners), Capua reticulana, Carposina niponensis(peach fruit moth), Chilo spp., Chlumetia transversa(mango shoot borer), Choristoneura rosaceana(obliquebanded leaf roller), leafroller)), Chrysodeixis spp.), Cnaphalocerus medinalis (grass leafroller), Colias spp., Conpomorpha cramerella, Cossus cossus (carpenter moth), Crambus spp. (sod webworms), Cydia funebrana (plum fruit moth), Cydia molesta (oriental fruit moth), Cydia nignicana (pea moth), Cydia pomonella (codling moth), Darna diducta, Diaphania spp. (stem borer), borers), Diatraea spp. (stalk borers), Diatraea spp. (sugarcane borer), Diatraea graniosella (southwester corn borer), Earias spp. (bollworms), Earias insulata (Egyptian bollworm), Earias vitella (rough northern bollworm), Ecdytopopha aurantianum, Elasmopalpus lignosellus (lesser cornstalk borer), Epiphysias postruttana (light brown apple moth), Ephestia spp. (flour moths), Ephestia cautella)(almond moth), Ephestia elutella(tobbacomoth), Ephestia kuehniella(Mediterranean flour moth), Epimeces spp.), Epinotia aporema, Erionotathrax (banana skipper), Eupoecilia ambiguella (grapeberry moth), Euxoa auxiliaris (army cutworm), Feltia spp. (cutworms), Gortyna spp. (stemblerers), Grapholitamolesta (oriental fruit moth), Hedylepta indicate (bean leaf webber), Helicoverpa sp p. (noctuids), Helicoverpa armigera, Helicoverpa zea, Heliothis spp., Heliothis budworm (Heliothis virescens), Hellula undalis (cabbage webworm), Indarbela spp. (root borers), Keiferia lycopersicella, Leucinodes orbonalis, Leucoptera malifoliella, Lithocollectis spp., Lobesia botrana (grape fruitmoth), Loxagrotis spp., Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil palm bagworm), bagworm) and Malacosoma spp.)(tent caterpillars), Mamestra brassicae(cabbage armyworm), Maruca testulalis(bean pod borer), Metisa plana, Mythimna unipuncta(true armyworm), Neoleucinodes elegantalis, Nymphula depunctalis, Operophtherabrumata, Ostrinia nubilalis(European corn borer), Oxydia vesulia, Pandemis cerasana(common currant tortrix), Pandemis heparana(brown apple tortrix), Papilio demodocus, Pectinophora gossypiella(pink bellworm), (bottomworm), Peridroma spp. (cutworm), Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phyllocnisitis citrella, Phyllonorycter spp., Pieris rapae, Plathypena scabra, Plodia interpunctella, Plutellaxylostella (diamondback moth), Polychrosis viteana (grapeberry moth), Prays endocarpa, Prays olive moth oleae) (olive moth), Pseudaletia spp.) (spodoptera), Spodoptera litura Fabricius, Pseudaletia unipunctata (armyworm), Pseudoplusia includes (, Rachiplusia nu, Chilo suppressalis (Walker), Scirpophaga incertulas, Sesamia spp. (stem borers), Sesamia inferens (pink rice stem borer), Spodoptera frugiperda (JESmmith), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp.), Spodoptera exigua, Spodoptera fugiperda, Spodoptera oridania (southern armyworm), Synanthedon spp., Thecla basilides, Thermisia gemmatalis, Tineola bisselliella (webbing clothesmoth), Trichoplusia ni (pieris rapae), Pierisrapae Linne (pieris rapae), Tuta absoluta;.

[0045] Furthermore, the lepidopteran pests include Plutella xylostella, Spodoptera exigua, Spodoptera litura, Fall Armyworm, Chilo suppressalis, Cotton bollworm, and Pieris rapae.

[0046] The present invention also provides a method for using the insecticidal composition containing benzoylureas as described above, specifically applying an effective dose to the pests to be controlled or the medium in which they grow.

[0047] The insecticidal composition of the present invention has the following advantages:

[0048] 1) The insecticide composition of the present invention can produce a significant synergistic effect within a certain ratio range, thereby improving the toxicity and rapidity of the agent;

[0049] 2) The insecticide composition of the present invention can delay the resistance of target pests and extend the service life of the product;

[0050] 3) The insecticide composition of the present invention expands the control spectrum while reducing the amount of pesticides used, thereby reducing the pressure on the ecological environment and agricultural production costs. DETAILED DESCRIPTION

[0051] The present invention is further described below with reference to the examples. The percentages in the examples are all percentages by weight, but the present invention is not limited thereto.

[0052] The composition of the present invention can be provided in the form of a preparation. It can be prepared into a suspension, emulsifiable concentrate, water dispersible granules, aqueous emulsion, granules, wettable powder, dispersible oil suspension, etc. as needed. The content of the active ingredient in the composition of the present invention depends on the application amount when used alone, and also depends on the mixing ratio and the degree of synergistic effect. The optimal range of the active ingredient content varies according to the type of preparation of the composition.

[0053] Formulation Examples

[0054] Preparation Example 1: 24% compound of formula (I)·difluanidazole suspension (4:20)

[0055] Preparation formula: 4% compound of formula (I), 20% diflubenzuron, 5% sodium sulfate of fatty alcohol polyoxyethylene ether, 1.5% sodium salt of polycarboxylic acid, 3.5% styrene phenol polyoxyethylene ether phosphate, 0.8% magnesium aluminum silicate, 0.2% xanthan gum, 0.5% sodium sorbate, 5% ethylene glycol, 0.5% organosilicon defoamer, and deionized water to make up the balance;

[0056] Preparation method: Add active ingredients to the wetting dispersant and defoamer, use zirconium oxide beads, and use a sand mill to wet grind to D 90 (90% of the particle size) <10 μm, and a crushed slurry is obtained. A thickener, antifreeze agent, preservative, etc. are added to the crushed slurry and mixed evenly, and deionized water is added to 100%, and a suspension product is obtained by high-speed shearing.

[0057] Preparation Example 2: 30% compound of formula (I)·thiocarbamide suspension (5:25)

[0058] Preparation formula: 5% compound of formula (I), 25% thiocarbamide, 2% fatty alcohol polyoxyethylene ether phosphate, 1% sodium polycarboxylate, 2.5% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 3.5% sodium lignin sulfonate, 0.8% magnesium aluminum silicate, 0.2% xanthan gum, 0.5% sodium sorbate, 4.5% propylene glycol, 0.5% organosilicon defoamer, and deionized water to make up the balance;

[0059] Preparation method: Same as Preparation Example 1.

[0060] Preparation Example 3: 6% compound of formula (I)·hexaflumuron emulsifiable concentrate (5:1)

[0061] Preparation formula: 5% compound of formula (I), 1% hexaflumuron, 10% propylene carbonate, 1.5% calcium dodecylbenzenesulfonate, 13.5% tristyrylphenol polyoxyethylene ether, 20% N,N-dimethylformamide, 2% soybean oil, 28% cyclohexanone, and methyl oleate makes up the balance;

[0062] Preparation method: firstly add the active ingredient into the solvent and completely dissolve it, then add the emulsifier and the like and stir evenly to form a uniform and transparent oily liquid, and then fill it to prepare the emulsifiable concentrate preparation of the composition of the present invention.

[0063] Preparation Example 4: 4.5% compound of formula (I)·thiofluanidone emulsifiable concentrate (2:2.5)

[0064] Preparation formula: 2% compound of formula (I), 2.5% thiocarbamide, 10% propylene carbonate, 1.5% calcium dodecylbenzenesulfonate, 13.5% tristyrylphenol polyoxyethylene ether, 20% N,N-dimethylformamide, 0.5% BHT, 2.5% corn oil, 25% cyclohexanone, and methyl oleate makes up the balance;

[0065] Preparation method: Same as Preparation Example 3.

[0066] Preparation Example 5: 30% compound of formula (I)·difluanid WP (13:17)

[0067] Preparation formula: 13% compound of formula (I), 17% diflubenzuron, 8% naphthalenesulfonate formaldehyde condensate, 10% tea saponin, 2% sodium lauryl sulfate, 5% attapulgite, and kaolin makes up the balance;

[0068] Preparation method: Active ingredients, other functional adjuvants and fillers are mixed according to the formula ratio, stirred evenly in a stirring kettle, and ground and mixed evenly for multiple times by a jet mill to prepare the wettable powder of the composition of the present invention.

[0069] Preparation Example 6: 11% compound of formula (I)·hexaflumuron water dispersible granules (9.5:1.5)

[0070] Preparation formula: 9.5% compound of formula (I), 1.5% hexaflumuron, 7% sodium lignin sulfonate, 7% naphthalene sulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 4.5% attapulgite, 20% starch, and kaolin makes up the balance;

[0071] Preparation method: According to the formula ratio of the embodiment, the active ingredient is added to the carrier, and a surfactant and other functional additives are added thereto, mixed, and after air flow pulverization, 10-25% of water is added, and then kneading, granulation, drying and sieving are performed to obtain a water-dispersible granule product.

[0072] Indoor biological activity assay

[0073] Test basis: Refer to the agricultural industry standards "Guidelines for Indoor Bioassay Tests of Pesticides Insecticides Part 6: Insect Dipping Method" (NY / T 1154.6-2006), "Guidelines for Indoor Bioassay Tests of Pesticides Insecticides Part 7: Determination of Combined Action of Mixtures" (NY / T 1154.7-2006), "Guidelines for Indoor Bioassay Tests of Pesticides Insecticides Part 14: Leaf Dipping Method" (NY / T1154.14-2008), etc.

[0074] Test target: beet armyworm;

[0075] Test method: leaf dipping method combined with insect dipping method;

[0076] Drug preparation: The test drug was dissolved in acetone and prepared into 5 series of concentrations using 0.1% Tween 80 aqueous solution.

[0077] Test materials: Use a hole puncher to punch leaf discs (1.5 cm in diameter), immerse them in the drug solution for 10 seconds, wait for the solution to dry naturally, then place the cabbage pieces in a petri dish lined with moisturizing filter paper, place 20 3rd instar larvae in the drug solution for 5 seconds, absorb the excess drug solution with filter paper, and place the test insects in the petri dish with leaves immersed in the corresponding concentration;

[0078] Experimental treatment: Each treatment was repeated 4 times, and the blank treatment was used as the control. The treated test insects were placed in an artificial intelligence culture room at 25±1℃, light duration L:D=16h:8h, and relative humidity of 65%±5% for breeding.

[0079] Investigation method: Check the experimental results after 72 hours. Touch the insect body with the tip of a brush. If there is no reaction, it is considered dead. Count the number of live and dead insects in each treatment and calculate the mortality rate.

[0080] Data statistics and analysis:

[0081] Based on the survey data, the adjusted mortality rate of each treatment was calculated.

[0082] The calculation results are retained to two decimal places:

[0083]

[0084] Where:

[0085] P——mortality rate, in percentage (%);

[0086] K——indicates the number of dead insects, in units of heads;

[0087] N——represents the total number of insects treated, in heads.

[0088]

[0089] Where:

[0090] P1——adjusted mortality rate, in percentage (%);

[0091] P t ——Treatment mortality rate, expressed as percentage (%);

[0092] P0——blank control mortality rate, in percentage (%).

[0093] If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made; if the control mortality rate is greater than 20%, the test needs to be repeated.

[0094] The data were processed by probability value analysis and analyzed by DPS statistical analysis system to obtain the toxicity regression line, LC 50 The activity of the test agent on the biological test material was evaluated by using the value, 95% confidence limit and correlation coefficient r.

[0095] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0096]

[0097] Where:

[0098] ATI——Actual Toxicity Index of Mixture;

[0099] S——LC of standard pesticide 50 , the unit is milligrams per liter (mg / L);

[0100] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0101] TTI=TI A * P A +TI B * P B

[0102] Where:

[0103] TTI – Theoretical Toxicity Index of Mixtures;

[0104] TI A ——A: toxicity index of the agent;

[0105] P A ——The percentage of agent A in the mixture, in percentage (%);

[0106] TI B ——Toxicity index of agent B;

[0107] P B ——The percentage of agent B in the mixture, in percentage (%).

[0108]

[0109] Where:

[0110] CTC – Co-toxicity coefficient;

[0111] ATI——Actual Toxicity Index of Mixture;

[0112] TTI - Theoretical Toxicity Index of Mixture.

[0113] The co-toxicity coefficient of the combination CTC ≥ 120 shows a synergistic effect; CTC ≤ 80 shows an antagonistic effect; 80 < CTC < 120 shows an additive effect.

[0114] Test results:

[0115] Combined toxicity of the mixture to Spodoptera exigua: LC of the compound of formula (I) against Spodoptera exigua 50 The content of the compound of formula (I) is 6.11 mg / L. The mixture of compound of formula (I) with diflubenzuron, fluazifop-urea and hexaflumuron has a good combined effect on Spodoptera exigua, and shows obvious synergistic effect at a certain mass ratio.

[0116] The results in Table 1 show that when the weight ratio of the compound of formula (I) and diflubenzuron to beet armyworm is 1:35 to 35:1, the co-toxicity coefficient is greater than 120, and the mixture of the two exhibits a synergistic effect within this weight ratio range; when the weight ratio of the compound of formula (I) and diflubenzuron to beet armyworm is 1:18 to 18:1, the co-toxicity coefficient is greater than 150, which has an obvious synergistic effect.

[0117] Table 1 The results of the toxicity test of different ratios of the compound of formula (I) and diflubenzuron against Spodoptera exigua

[0118]

[0119] The results in Table 2 show that when the weight ratio of the compound of formula (I) and cyfluthrin to beet armyworm is 1:50-27:1, the co-toxicity coefficient is greater than 80, and the mixture of the two exhibits an additive or synergistic effect within this weight ratio range; when the weight ratio of the compound of formula (I) and cyfluthrin to beet armyworm is 1:32-27:1, the co-toxicity coefficient is greater than 120, which has an obvious synergistic effect.

[0120] Table 2 Toxicity test results of different ratios of the compound of formula (I) and triflumuron against Spodoptera exigua

[0121]

[0122]

[0123] The results in Table 3 show that when the weight ratio of the compound of formula (I) and hexaflumuron to beet armyworm is 1:27 to 56:1, the co-toxicity coefficient is greater than 80, and the mixture of the two exhibits an additive or synergistic effect within this weight ratio range; when the weight ratio of the compound of formula (I) and hexaflumuron to beet armyworm is 1:27 to 27:1, the co-toxicity coefficient is greater than 140, which has an obvious synergistic effect.

[0124] Table 3 Toxicity test results of different ratios of the compound of formula (I) and hexaflumuron against Spodoptera exigua

[0125]

[0126] Field efficacy examples

[0127] Test crops and targets: green onion, beet armyworm;

[0128] Experimental location: Sunzhuang green onion planting field in Queshan County, Zhumadian City, Henan Province;

[0129] Application equipment: 3WBS-16 electric backpack sprayer;

[0130] Trial time: September 15, 2023;

[0131] Experimental environment: The cultivation conditions of all experimental plots are uniform and consistent, and the same fertilizer and water management level is adopted;

[0132] Test drug:

[0133] Table 4 Field test design and dosage

[0134]

[0135] Test method: Apply the pesticide once at the early stage of beet armyworm outbreak.

[0136] Plot area and replication: randomized block arrangement, 20m per plot 2, each treatment was repeated 4 times.

[0137] Methodology:

[0138] 1) Drug safety evaluation.

[0139] Observe the effects of different pesticides on the growth of green onions 1, 3, 7, and 14 days after application, and record whether there is any pesticide damage. If there is any pesticide damage, record the type, degree, duration, recovery, and other related information.

[0140] 2) Investigation on prevention effectiveness.

[0141] Five random sampling points were taken in each plot, with 10 plants fixed at each point. The number of beet armyworms on all the onion tubes of the whole plant was investigated. The base number of insects was investigated before spraying, and the number of remaining insects was investigated 3d and 14d after spraying.

[0142] Calculation formula and data analysis:

[0143]

[0144] Test results:

[0145] Safety: According to visual observations at 1d, 3d, 7d, and 14d after application, it was found that none of the pesticides used in this experiment caused any damage to the growth of green onions, indicating that the pesticides were safe under the conditions of this experiment.

[0146] Results of field efficacy test: As can be seen from Table 5, 3 days after application, 24% compound of formula (I)·flumuron suspension concentrate (4:20), 6% compound of formula (I)·hexaflumuron emulsifiable concentrate (5:1), and 30% compound of formula (I)·flumuron suspension concentrate (5:25) showed good rapid effectiveness in controlling beet armyworm in onion fields, with control effects of 82.27%, 83.00%, and 80.01%, respectively. Each treatment was significantly higher than the control single agent.

[0147] Table 5 Field control effect of different pesticides on beet armyworm (3 days after application)

[0148]

[0149] Note: The above data are the average values ​​of 4 repetitions, and the values ​​are rounded to two decimal places. Different letters after the efficacy data in the same column indicate significant differences (P < 0.05).

[0150] As can be seen from Table 6, 14 days after application, 24% compound of formula (I)·flumuron suspension concentrate (4:20), 6% compound of formula (I)·hexaflumuron emulsifiable concentrate (5:1), and 30% compound of formula (I)·flumuron suspension concentrate (5:25) showed good sustained effectiveness against beet armyworm in onion fields, with control effects of 87.74%, 90.81%, and 86.44%, respectively, and each treatment was significantly higher than the control single agent.

[0151] Table 6 Field control effect of the same pesticide on beet armyworm (14 days after application)

[0152]

[0153] Note: The above data are the average values ​​of 4 repetitions, and the values ​​are rounded to two decimal places. Different letters after the efficacy data in the same column indicate significant differences (P < 0.05).

[0154] The insecticide composition or the preparation obtained by compounding the present invention has a significant control effect, and is superior to a single agent in delaying the generation of drug resistance and prolonging drug retention. In addition, no compound agent was found to cause phytotoxicity to crops (green onions) in the test, indicating that the insecticide composition or preparation obtained can reduce production costs and use costs and is safe for crops when the insecticide synergistic synergy is improved.

[0155] Although the present invention has been described in detail above with general instructions and specific implementation schemes, it is obvious to those skilled in the art that some modifications or improvements can be made on the basis of the present invention. Therefore, these modifications or improvements made without departing from the spirit of the present invention are within the scope of protection claimed by the present invention.

Claims

1. An insecticidal composition containing benzoylureas, characterized in that: The invention comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is a compound of formula (I) and has the following structure: The active ingredient B is a benzoyl urea compound.

2. The insecticidal composition according to claim 1, characterized in that: The benzoylurea compounds include lufenuron, diflubenzuron, diflubenzuron, bistrifluanuron, chlorfluazuron, fluazifop, flufenoxuron, flubenzuron, fluazifop, flubenzuron, flufluanidone, flufenoxuron ...; Preferably, the benzoyl urea compound is diflubenzuron, chloranil, and hexaflumuron.

3. The insecticidal composition according to claim 1, characterized in that: The mass ratio between the active ingredient A and the active ingredient B is 1:50 to 56:1; Preferably, the mass ratio between the active ingredient A and the active ingredient B is 1:35 to 35:

1.

4. The insecticidal composition according to claim 1, characterized in that: The mass ratio of the compound of formula (I) to lufenuron is 1:35 to 35:1, the mass ratio of the compound of formula (I) to diflubenzuron is 1:32 to 27:1, and the mass ratio of the compound of formula (I) to diflubenzuron is 1:27 to 27:1; Preferably, the mass ratio of the compound of formula (I) to lufenuron is 1:18 to 18:1, the mass ratio of the compound of formula (I) to diflubenzuron is 1:7 to 27:1, and the mass ratio of the compound of formula (I) to chlorfenapyr is 1:14 to 27:

1.

5. The insecticidal composition according to claim 1, characterized in that: Based on the total mass of the insecticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 0.5% to 90%; Preferably, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 1% to 85%.

6. The insecticidal composition according to claim 1, characterized in that: In addition to the active ingredients, the insecticide composition also includes agriculturally acceptable auxiliary ingredients, which are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists or carriers.

7. The insecticidal composition according to claim 6, characterized in that: The insecticide composition is prepared into a formulation form permitted in agriculture, and the formulation form is selected from a solid formulation and / or a liquid formulation; Preferably, the solid preparation is selected from wettable powders and water-dispersible granules; the liquid preparation is selected from emulsifiable concentrates, aqueous emulsions, microemulsions, suspensions, suspoemulsions, and dispersible oil suspensions.

8. Use of the insecticide composition according to any one of claims 1 to 7 in preventing and controlling agricultural and forestry pests and sanitary pests.

9. The use according to claim 8, characterized in that: The agricultural and forestry pests and sanitary pests are lepidoptera pests.

10. The insecticidal composition according to claim 1, characterized in that: The insecticide composition is applied to the pests to be controlled or the medium where they grow in an effective dose.

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