Anti-gravity essence and preparation method thereof

Abstract

According to the anti-gravity essence and the preparation method thereof, the anti-gravity essence comprises a water phase and an oil phase, and the mass ratio of the oil phase is 10-15%; the oil phase comprises simmondsia chinensis seed oil, almond oil, camellia seed oil and sunflower seed oil in a mass ratio of 2: 0.8: 2: 5; the water phase is prepared from the following components in parts by mass: 0.1 to 0.5 part of mono / diglycerol fatty acid ester, 5 parts of xylitol, 0.5 part of sodium hyaluronate, 5 parts of sodium lactate, 2 parts of starch, 7.5 to 20 parts of ascorbyl palmitate, 2 to 5 parts of collagen, 2 to 5 parts of nicotinamide, 2 to 5 parts of jasmine flower extracting solution and deionized water. By optimizing formula components, effectively reducing cost and combining a micro-channel preparation process, the stability, permeability and anti-aging effect of the anti-gravity essence are improved, the skin aging process is slowed down, fine wrinkles and wrinkles are improved, and meanwhile, the anti-gravity essence has good safety and tolerance and has very high practicability and wide applicability.

Description

Technical Field

[0001] The invention relates to an anti-gravity essence, in particular to an anti-gravity essence and a preparation method thereof, and belongs to the technical field of cosmetics and skin care. Background Art

[0002] Anti-gravity essence is a skin care product that is mainly used to help improve skin loosening, sagging and fine lines. The main ingredients of anti-gravity essence are usually caviar extract, peptides, etc. These ingredients are rich in unsaturated fatty acids, proteins, vitamins and trace elements, which can provide nutrients to the skin and keep the skin moisturized and smooth. The price of each ingredient is relatively high.

[0003] At present, the preparation of anti-gravity essence is mainly based on machine stirring method, which uses machine stirring equipment to mix, disperse and emulsify the oil phase and the water phase to form a stable emulsion.

[0004] When using machine stirring to emulsify and prepare anti-gravity essence, the emulsification effect will be affected by many factors, including stirring equipment, stirring speed, emulsifier selection, temperature adjustment, etc. There are many variables. Each process link directly affects the stability, texture and efficacy of the product.

[0005] Therefore, it is necessary to provide a low-cost, process-stable anti-gravity essence and a preparation method thereof. Summary of the invention

[0006] To overcome the deficiencies of the prior art, the present invention aims to provide an anti-gravity essence and a preparation method thereof.

[0007] In order to achieve the above object, the present invention adopts the following technical solution:

[0008] An anti-gravity essence, comprising a water phase and an oil phase, wherein the oil phase accounts for 10-15% by weight;

[0009] The oil phase includes jojoba seed oil, almond oil, camellia seed oil, and sunflower seed oil in a mass ratio of 2:0.8:2:5;

[0010] In parts by mass, the aqueous phase includes 0.1-0.5 parts of mono- and di-glycerol fatty acid esters, 5 parts of xylitol, 0.62 parts of sodium hyaluronate, 6.25 parts of sodium lactate, 2.5 parts of starch, 7.5-20 parts of ascorbyl palmitate, 2.5-6.25 parts of collagen, 2-5 parts of niacinamide, 2-5 parts of jasmine extract, and some deionized water.

[0011] The above mono- and di-glycerol fatty acid esters are 1 wt %.

[0012] The mass proportion of the above oil phase is 10%.

[0013] The above-mentioned collagen is 2 wt%.

[0014] The method for preparing the anti-gravity essence is to pump the water phase and the oil phase into the channel of the microchannel reactor respectively, and after mixing, obtain a uniform and stable emulsified liquid, which is the anti-gravity essence;

[0015] The heat exchanger temperature of the microchannel reactor is 83°C.

[0016] Furthermore, the inner diameter of the channel of the above-mentioned microchannel reactor is 21.6 mm.

[0017] Furthermore, the pump speed of the oil phase is 1 ml / min.

[0018] Furthermore, the emulsified liquid does not contain mixed waste.

[0019] The time for receiving the waste is Ts=2.7÷V×60×5,

[0020] Where Ts is the waste receiving time and V is the total flow rate.

[0021] The present invention is beneficial in that:

[0022] The anti-gravity essence and preparation method of the present invention optimize the formula components, effectively reduce the cost, and improve the stability, permeability and anti-aging effect of the anti-gravity essence by combining the microchannel preparation process, so as to better meet the needs of users with different skin types and needs, and have the following advantages:

[0023] 1. High efficiency: The high shear force and turbulence effect inside the microchannel make the emulsification process more efficient. Compared with the traditional mechanical stirring method, the microchannel process can mix the two phases more quickly and refine them into an emulsion, saving time and energy.

[0024] 2. Precise control: The emulsification process can be precisely controlled by adjusting the microchannel size, flow rate, temperature and other parameters to obtain the desired emulsification effect. This precise control capability helps produce high-quality emulsion products to meet the needs of different skin types.

[0025] 3. Uniformity and stability: Microchannels are usually at the micron level. The high shear force and turbulence effect generated by the microchannels are used to achieve mixing, dispersion and emulsification of liquids. The resulting emulsion has a more uniform particle size distribution and higher stability, making the anti-gravity essence produced have better uniformity and stability.

[0026] 4. Save raw materials: Microchannels can fully mix raw materials in a shorter time, reducing the loss and waste of raw materials. At the same time, the emulsification effect is more thorough, the utilization rate of the product is also higher, and the production cost is effectively reduced.

[0027] 5. Environmental protection and sustainability: Compared with traditional mechanical stirring methods, microchannel processes usually require fewer additives and agents, reduce environmental pollution, and are in line with the concept of sustainable development. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 The anti-gravity essence prepared in Example 1.

[0029] Figure 2 This is the anti-gravity essence prepared in Comparative Example 1.

[0030] Figure 3 This is the anti-gravity essence prepared in Example 2.

[0031] Figure 4 This is the anti-gravity essence prepared in Example 3.

[0032] Figure 5 This is the anti-gravity essence prepared in Example 4. DETAILED DESCRIPTION

[0033] The present invention is described in detail below with reference to the accompanying drawings and specific embodiments.

[0034] An anti-gravity essence, the components of which are shown in Table 1 below:

[0035] Table 1

[0036]

[0037]

[0038] Example 1

[0039] Preparation method of anti-gravity essence:

[0040] (1) Turn on the microchannel reactor equipment and adjust the syringe parameters to an inner diameter of 21.6 mm.

[0041] (2) Two syringes (channels) suck ethanol, then adjust the flow rate of the two pumps to 2 ml / min and start the cleaning equipment; after cleaning, adjust the temperature of the heat exchanger to 83 °C for preheating.

[0042] (3) After preheating, start injecting the pre-prepared water phase and oil phase. According to the ratio of water to oil, adjust the flow rate ratio of the two pumps, water: oil = 4:1, and the flow rate is also set to 4:1.

[0043] (4) Take a beaker to collect the waste liquid, and calculate the time for collecting the waste by the formula Ts = 2.7 ÷ V × 60 × 5, Ts is 202.5 seconds. V represents the total flow rate, V = 5 ml / min.

[0044] Because the microchannels are cleaned with water and ethanol in turn before preparation, there will be products left after cleaning. When the reaction materials enter, the products obtained in the early stage are affected and the quality is not high. These products are waste and therefore need to be eliminated.

[0045] (5) After the waste is collected, change the beaker to collect the newly formed emulsion. The emulsion is clear and there is no obvious stratification phenomenon, such as Figure 1 shown.

[0046] (6) The reaction is completed in 3 minutes and 20 seconds.

[0047] (7) After the reaction is finished, the heat exchanger temperature is adjusted to 20°C to cool down; at the same time, two syringes are used to absorb water to clean the equipment, and the pump rates of the two syringes are adjusted to the same ratio. When the temperature drops to 20°C, two syringes are used to absorb ethanol to clean the equipment.

[0048] In a microchannel reactor, the flow rate and flow rate of the liquid (water phase and oil phase) can be controlled by microfluidics technology, so that the two phases can enter the microchannel in a precise and controllable manner. The water phase and the oil phase are mixed under high speed and high shear to form an emulsion.

[0049] Comparative Example 1

[0050] Machine mixing method:

[0051] The first step is to prepare the necessary raw materials.

[0052] In the second step, the B phase mono- and diglycerol fatty acid esters, xylitol, sodium hyaluronate, sodium lactate, starch, ascorbyl palmitate, collagen, niacinamide, jasmine extract, and deionized water are weighed and added to container b in sequence. The A phase jojoba seed oil, almond oil, camellia seed oil, and sunflower seed oil are weighed and added to container a in sequence.

[0053] The third step is to heat the constant temperature water bath to 80°C and use a handheld homogenizer to mix and stir phase A and phase B to ensure that all ingredients are fully mixed and dissolved, and continue to keep warm and heat.

[0054] Step 4: fully mix phase A and phase B in a constant temperature water bath at 80°C, and continuously stir and emulsify until a uniform emulsion is formed to obtain a product such as Figure 2 shown.

[0055] Step 5. Pour the prepared anti-gravity essence into a clean container and seal it in a cool and dry place.

[0056] A. Performance Testing

[0057]

[0058] A1. Appearance test, see Table 2 below:

[0059] Table 2

[0060]

[0061]

[0062] Test method:

[0063] Apply 0.3 ml of the product evenly on different parts of the subject's arm skin, absorb the sample with paper after 60 seconds, observe and feel and record. Repeat three times and take the average value.

[0064] A2. Physical and chemical performance test, see Table 3 below:

[0065] Table 3

[0066]

[0067] Test method:

[0068] Apply 0.3 ml of the product evenly on different parts of the subject's arm. After 60 seconds, remove the sample with paper and use the smart skin analyzer to measure the skin's moisture, oil content, texture, skin color, pigment, sensitivity and pores. Repeat three times and take the average value.

[0069] As can be seen from Table 2 above, the anti-gravity essence prepared by the traditional process (machine stirring method) has a delicate touch when it contacts the skin, does not cause roughness or irritation, and can gently contact the skin surface. Secondly, the texture of the essence after application has a light and refreshing feeling, and is slightly greasy and remains on the skin surface. Then, the moisturizing degree is better after use, easier to absorb, can provide sufficient moisture, keep the skin soft and smooth, and can provide deep nourishment and moisturizing in a short time.

[0070] The anti-gravity essence prepared by the microchannel emulsification method has a light texture and is easy to apply and absorb. It will leave a silky and soft feeling on the skin without adding extra burden or greasiness to the skin. It can be quickly absorbed by the skin without leaving a sticky or heavy feeling on the surface.

[0071] As can be seen from Table 3 above, the anti-gravity essence prepared by the microchannel emulsification method is better than the traditional process in terms of moisture, oil content, skin color, etc., indicating that the emulsification effect of the microchannel emulsification method is better.

[0072] Example 2

[0073] A single factor experiment was conducted on the dosage of emulsifier mono- and di-glycerol fatty acid esters, and the experimental design is shown in Table 4 below:

[0074] Table 4

[0075]

[0076] As shown in Table 4 above, when the addition amount of mono- and di-glycerol fatty acid esters is 0.1 g, the product state is a homogeneous system, a light yellow liquid, and almost no foam, such as Figure 3 shown.

[0077] Example 3

[0078] The dosage of the emulsifier mono- and di-glycerol fatty acid esters was determined to be 0.10%, and the proportion of the oil phase was changed to study the effect of the proportion of the oil phase on the product. The experimental design is shown in Table 5:

[0079] Table 5

[0080]

[0081]

[0082] As shown in Table 5 above, when the amount of mono- and di-glycerol fatty acid esters added as the emulsifier is 0.1 g, the proportion of the oil phase (Phase A in Table 1) is determined to be 10%, and the product state is a homogeneous system, light yellow liquid, and slightly viscous. Figure 4 shown.

[0083] Example 4

[0084] Based on Table 5, the dosage of emulsifier mono- and di-glycerol fatty acid esters was determined to be 0.10 g, the proportion of the oil phase was 10%, and the dosage of collagen was changed to study the effect of the dosage of collagen on the product state. The experimental design is shown in Table 6 below:

[0085] Table 6

[0086]

[0087] As shown in Table 6 above, when the amount of mono- and di-glycerol fatty acid esters added as emulsifier is 0.10 g and the proportion of the oil phase is 10%, the proportion of collagen is determined to be 2%, and the product state is a homogeneous system, light yellow liquid, and slightly viscous. Figure 5 shown.

[0088] Determination of DPPH antioxidant activity:

[0089] Determination of the ability to scavenge DPPH free radicals: prepare 0.1 mmol / L DPPH ethanol solution.

[0090] Accurately pipette 0ml, 0.4ml, 0.8ml, 1.2ml, 1.6ml, 2.0ml, 2.0ml of jasmine extract and 2.0ml, 1.6ml, 1.2ml, 0.8ml, 0.4ml, 0.60ml and 6.0ml of newly prepared DPPH solution into the reagent, shake well, keep aside from light, wait for reaction for 30 minutes, measure the absorbance at 517nm on a UV spectrophotometer, and record the data.

[0091] The blank control was an equal volume of distilled water to measure the absorbance of unreacted DPPH in the ethanol solution.

[0092] The antioxidant capacity of jasmine extract samples was analyzed by plotting the free radical scavenging rate as the ordinate and the sample concentration as the abscissa. Three parallel experiments were performed. The scavenging capacity of the extract samples for DPPH free radicals was calculated according to formula (4-1):

[0093]

[0094] Wherein, I represents the scavenging rate of free radicals (%);

[0095] Ai represents the absorbance of the mixture of jasmine extract and DPPH solution (2 ml extract + 6 ml DPPH solution);

[0096] Aj represents the absorbance of the sample solution without DPPH solution (2 ml of extract + 6 ml of ethanol solution);

[0097] A0 represents the absorbance of the DPPH solution when no sample is added (2 ml of ethanol solution + 6 ml of DPPH solution).

[0098] The free radical scavenging rate of jasmine extract is shown in Table 7 below:

[0099] Table 7

[0100]

[0101] Research has found that jasmine extract has a good antioxidant effect, with a free radical scavenging rate of up to 94.2%.

[0102] Through in-depth research, the present invention has found that in the composition of the anti-gravity essence, niacinamide plays the role of brightening skin tone, moisturizing and anti-oxidation; ascorbyl palmitate (vitamin C) promotes the synthesis of keratin, collagen and the like, and collagen improves the elasticity and firmness of the skin and reduces the appearance of fine lines and wrinkles; sodium hyaluronate firmly retains moisture, helps the skin lock in moisture, and adapts to the moisturizing needs under different environmental humidity; jasmine extract plays the role of anti-oxidation and anti-inflammatory.

[0103] The low-temperature emulsification method is used to retain the activity of active substances, and they are successfully combined with natural extracts with antioxidant properties to prepare anti-gravity essence. Due to the special structure of liquid crystal, the anti-gravity essence forms a "net-like" structure on the skin surface, allowing the skin to breathe and move freely as if in a suspended state, making it easier for the skin to absorb nutrients, thereby achieving better skin care effects.

[0104] The prepared anti-gravity essence was characterized, including appearance test, physical and chemical performance test, etc. The experimental results showed that the prepared essence had good sample appearance and skin feel results. And through the texture and pore tests in the skin feel test, it was fed back that it had significant anti-aging effects, could slow down the aging process of the skin, improve fine lines and wrinkles, and had good safety and tolerance.

[0105] Anti-gravity essence has anti-gravity properties mainly because:

[0106] (1) The synergistic effect of vitamin C, collagen and sodium hyaluronate can continuously stimulate the regeneration of skin cells, promote the synthesis of collagen and hyaluronic acid, thereby improving the elasticity and firmness of the skin and achieving an anti-gravity effect.

[0107] (2) Jasmine extract has excellent anti-free radical and antioxidant effects, which can help soothe the skin and promote the penetration of various functional nutrients into the dermis, thereby enhancing the efficacy.

[0108] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the above embodiments do not limit the present invention in any form, and any technical solution obtained by equivalent replacement or equivalent transformation falls within the protection scope of the present invention.

Claims

1. An anti-gravity essence, characterized in that: The components include a water phase and an oil phase, wherein the mass proportion of the oil phase is 10-15%; The oil phase includes jojoba seed oil, almond oil, camellia seed oil, and sunflower seed oil in a mass ratio of 2:0.8:2:5; In parts by mass, the aqueous phase includes 0.1-0.5 parts of mono- and di-glycerol fatty acid esters, 5 parts of xylitol, 0.5 parts of sodium hyaluronate, 5 parts of sodium lactate, 2 parts of starch, 7.5-20 parts of ascorbyl palmitate, 2-5 parts of collagen, 2-5 parts of niacinamide, 2-5 parts of jasmine extract, and deionized water.

2. The anti-gravity essence according to claim 1, characterized in that: The mono- and di-glycerol fatty acid esters are 1 wt %.

3. The anti-gravity essence according to claim 1, characterized in that: The mass proportion of the oil phase is 10%.

4. The anti-gravity essence according to claim 1, characterized in that: The collagen is 2 wt %.

5. The method for preparing the anti-gravity essence according to any one of claims 1 to 4, characterized in that: By pumping the water phase and the oil phase into the channel of the microchannel reactor respectively and mixing them, a uniform and stable emulsified liquid is obtained, which is the anti-gravity essence; The heat exchanger temperature of the microchannel reactor is 83°C.

6. The method for preparing the anti-gravity essence according to claim 5, characterized in that: The inner diameter of the channel of the microchannel reactor is 21.6 mm.

7. The method for preparing the anti-gravity essence according to claim 5, characterized in that: The pump rate of the oil phase was 1 ml / min.

8. The method for preparing the anti-gravity essence according to claim 5, characterized in that: The emulsified liquid does not contain mixed waste materials, The time for receiving the waste is Ts=2.7÷V×60×5, Where Ts is the waste receiving time and V is the total flow rate.

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