Real-time online high-precision detection system and detection method for residual amount of reagent
By designing real -time online online to high -precision detection systems, using components such as weighing sensor modules and microprocessors to solve the problems that existing equipment cannot accurately monitor samples or reagent use conditions in real time, and realize high -precision, low -cost costs Multi -channel monitoring effect.
Patent Information
- Application Number
- CN202411157944.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-22
- Publication Date
- 2025-01-28
AI Technical Summary
Existing in vitro detection equipment cannot accurately monitor the use and residual amount of samples or reagents online in real time, and is costly and has low accuracy, especially in multi-channel situations.
Designed a high -precision detection system for reagent residuals in real time, including weighing sensor modules, computing amplifier circuits, filter circuits, AD sampling circuits, and MCU microprocessors. show.
A real -time online high -precision monitoring of the use of samples or reagents is realized, reducing costs, improving detection accuracy, and suitable for multi -channel monitoring.
Smart Images

Figure CN119374704A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of detection equipment, and in particular to a real-time online high-precision detection system and method for residual reagent amount. Background Art
[0002] Currently, when using in vitro testing equipment, users hope to be able to monitor the usage of consumables such as samples or reagents in real time online and accurately, so that users can clearly understand whether the current sample volume or reagent volume is sufficient, and how long the remaining samples or reagents can last.
[0003] Disadvantages / deficiencies in existing in vitro testing devices: 1) Existing in vitro testing equipment can only indirectly estimate the usage and residual amount of samples or reagents based on the cumulative number of samples, but the accuracy is not completely sufficient; 2) Existing in vitro detection equipment requires high measurement accuracy because it uses relatively small amounts of samples or reagents and is light in weight.
[0004] 3) Existing in vitro detection equipment uses a single-channel weighing detection circuit system. When using multiple channels, it is necessary to add the original detection system, which increases the cost. At the same time, multiple acquisition channels need to be switched by program control, which increases the task load. Summary of the invention
[0005] The present invention overcomes the shortcomings of the prior art and provides a real-time online high-precision detection system and method for residual reagents, which can accurately monitor the usage of consumables such as samples or reagents online, making it convenient for users to clearly understand in real time whether the current sample and reagent quantities are sufficient, and how long the remaining samples or reagents can last.
[0006] To achieve the above-mentioned purpose, the technical solution adopted by the present invention is: a real-time online high-precision detection system for the residual amount of reagents, comprising: a weighing sensor module, the weighing sensor module comprising a tray for testing, a placement area is provided on the tray, a weighing platform is provided on the placement area, a weighing sensor is provided between the weighing platform and the placement area of the tray, and a positioning groove for locating the reagent container to be tested is provided on the weighing platform; the weighing sensor is connected to a microprocessor through an operational amplifier circuit, a filter circuit, and an AD sampling circuit, and the microprocessor is electrically connected to a monitoring and display circuit through a communication interface circuit.
[0007] In a preferred embodiment of the present invention, the weighing sensor is connected to the input end of the operational amplifier circuit through the weighing sensor interface, the output end of the operational amplifier circuit is connected to the input end of the filter circuit, the output end of the filter circuit is connected to the input end of the AD sampling circuit, the microprocessor is an MCU microprocessor, and the output end of the AD sampling circuit is connected to the I / O interface of the MCU microprocessor.
[0008] In a preferred embodiment of the present invention, it also includes a multi-stage power supply circuit for supplying power to the weighing sensor module, operational amplifier circuit, filter circuit, AD sampling circuit, MCU microprocessor, communication interface circuit, and monitoring display circuit.
[0009] In a preferred embodiment of the present invention, the multi-stage power supply circuit includes a power supply module and a reference power supply circuit electrically connected to the power supply module. The power supply module adopts a +24V low-voltage DC single power supply, and the power supply module converts the power supply into +5V through a DC-DC regulated power supply conversion chip. The DC-DC regulated power supply conversion chip is used to power the LDO linear power supply chip, and is converted into 3.3V power supply by the LDO linear power supply chip.
[0010] In a preferred embodiment of the present invention, the number of channels of the operational amplifier circuit matches the number of the weighing sensor modules.
[0011] In a preferred embodiment of the present invention, the filter circuit is an RC filter circuit.
[0012] In a preferred embodiment of the present invention, the MCU microprocessor adopts the STM32FM series and supports CAN communication, 485 communication, or RS323 communication.
[0013] In a preferred embodiment of the present invention, the AD sampling circuit adopts an ADS114S08 sampling chip, and the sampling port of the ADS114S08 sampling chip is connected to a plurality of groups of weighing sensors, operational amplifier circuits, and filter circuits connected in series; the output end of the weighing sensor is connected to the input end of the operational chip in the operational amplifier circuit through two resistors, one of the input ends of the operational chip is connected to the positive power supply terminal of the operational chip through a resistor and a capacitor, and the GND pin of the operational chip is grounded. A capacitor and a resistor are connected in parallel between the other input end and the output end of the operational chip, and the output end of the operational chip is connected to the sampling port of the ADS114S08 sampling chip through a resistor and a capacitor connected in series in the filter circuit; The REFP0 port of the ADS114S08 sampling chip is connected to the REF5050 power chip of the reference power circuit, and the VOUT end of the REF5050 power chip is connected to the ADS114S08 sampling chip. The VOUT end of the REF5050 power chip is also grounded through capacitor C51 and a series resistor R51 and capacitor C52. The power end of the REF5050 power chip is connected to +12V, and the branch connection is grounded through capacitor C53. The ADS114S08 sampling chip is connected to the STM32F407ZET6 chip of the MCU microprocessor, the USART_TX port and USART_RX port of the STM32F407ZET6 chip are connected to the SP3232 chip of the RS232 communication interface circuit, and the TxOUT port and port of the SP3232 chip are connected to the P interface in the monitoring display unit interface; The power supply circuit includes a J5 interface connected to an external power supply. The output end of the J5 interface is connected to a diode D1 and outputs a +24V voltage. A capacitor C70 is connected in parallel at both ends of the diode D1 and is grounded through one end of a capacitor C71. The other end of the capacitor C70 is connected to the input end of the K7812-1000R3 chip through a resistor F1. The input end of the 7812-1000R3 chip is also grounded through a capacitor C71. The output end of the K7812-1000R3 chip outputs a +12V voltage. The output end of the K7812-1000R3 chip is connected to the input end of the K7805-500R3 chip, the output end of the K7805-500R3 chip is connected to the input end of the LM1117MP-3.3 / TR chip, the output end of the K7805-500R3 chip outputs a +5V voltage and is grounded through capacitor C73; the output end of the LM1117MP-3.3 / TR chip outputs a 3.3V voltage and is grounded through capacitor C74.
[0014] In a preferred embodiment of the present invention, a real-time online high-precision detection method for residual reagent comprises the following steps: Step 1: Place the reagent container to be tested on the weighing table of the corresponding weighing sensor module; Step 2, obtaining the weight of the reagent container to be tested on the weighing table in real time through the weighing sensor in the weighing sensor module; Step 3, the pressure operational amplifier circuit amplifies the signal of the weighing sensor of the reagent container to be detected obtained on the weighing table, and then filters out the interference signal or noise through the filter circuit, and converts the filtered signal into digital form through the AD sampling circuit, and inputs the converted digital signal into the MCU microprocessor for sampling, and the MCU microprocessor obtains the sampled detection signal; Step 4: The sampled detection signal obtained by the MCU microprocessor is transmitted to the monitoring and display circuit through the communication interface circuit, and displayed through the monitoring and display circuit.
[0015] In a preferred embodiment of the present invention, after step 3, the MCU microprocessor compares the acquired sampled detection signal with a preset threshold value, and issues an alarm or prompts shutdown due to insufficient margin according to the triggering margin threshold channel.
[0016] In a preferred embodiment of the present invention, all weighing added values, including the empty test agent containers, are cleared before real-time monitoring, and only the net value of the sample or reagent is monitored in real time.
[0017] The present invention solves the defects existing in the technical background, and the beneficial technical effects of the present invention are: The present invention provides a real-time online high-precision detection system and method for residual reagents, which can accurately monitor the usage of consumables such as samples or reagents online, so that users can clearly understand in real time whether the current sample and reagent quantities are sufficient, and how long the remaining samples or reagents can last. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] The present invention is further described below in conjunction with the accompanying drawings and embodiments.
[0019] Figure 1 It is a work flow chart of a preferred embodiment of the present invention; Figure 2 is a circuit diagram of a power supply circuit in a specific implementation circuit of a preferred embodiment of the present invention; Figure 3 is a circuit diagram of a sampling processing circuit in a specific implementation circuit of a preferred embodiment of the present invention; Figure 4 It is a structural schematic diagram of a weighing sensor module of a preferred embodiment of the present invention; Among them, 1. pallet, 2. weighing sensor, 3. weighing platform. DETAILED DESCRIPTION
[0020] The present invention will now be further described in detail with reference to the accompanying drawings and embodiments. These drawings are simplified schematic diagrams that only illustrate the basic structure of the present invention in a schematic manner, and therefore only show the components related to the present invention.
[0021] It should be noted that if there are directional indications (such as up, down, bottom, top, etc.) involved in the embodiments of the present invention, the directional indication is only used to explain the relative position relationship, movement, etc. between the components in a certain specific posture. If the specific posture changes, the directional indication will also change accordingly. The terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. Unless otherwise clearly specified and defined, the terms "set", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be directly connected, or indirectly connected through an intermediate medium, or it can be the internal connection of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances. Embodiment 1
[0022] like Figure 1 , Figure 2 , Figure 3 As shown, a real-time online high-precision detection system for the residual amount of reagents includes: a weighing sensor 2 module, the weighing sensor 2 module includes a tray 1 for testing, a placement area is provided on the tray 1, a weighing platform 3 is provided on the placement area, a weighing sensor 2 is provided between the weighing platform 3 and the placement area of the tray 1, and a positioning groove for positioning the reagent container to be detected is provided on the weighing platform 3; the weighing sensor 2 is connected to the MCU microprocessor through an operational amplifier circuit, a filter circuit, and an AD sampling circuit, and the MCU microprocessor is electrically connected to the monitoring display circuit through a communication interface circuit. The weighing sensor 2 is connected to the input end of the operational amplifier circuit through the weighing sensor 2 interface, the output end of the operational amplifier circuit is connected to the input end of the filter circuit, the output end of the filter circuit is connected to the input end of the AD sampling circuit, and the output end of the AD sampling circuit is connected to the I / O interface of the MCU microprocessor. The multi-stage power supply circuit supplies power to the weighing sensor 2 module, the operational amplifier circuit, the filter circuit, the AD sampling circuit, the MCU microprocessor, the communication interface circuit, and the monitoring display circuit.
[0023] Specifically, the multi-stage power supply circuit includes a power supply module and a reference power supply circuit electrically connected to the power supply module. The power supply module adopts a +24V low-voltage DC single power supply, which is converted into +5V power supply by a DC-DC regulated power supply conversion chip. The DC-DC regulated power supply conversion chip is used to power the LDO linear power supply chip, and is converted into 3.3V power supply by the LDO linear power supply chip.
[0024] Specifically, the signal generated by the weighing sensor 2 module when the weighing sensor 2 module performs real-time weighing is introduced into the detection system through the weighing sensor 2 interface for real-time monitoring; the signal received by the weighing sensor 2 interface is amplified by the operational amplifier circuit system to amplify the weak signal into a signal that can be collected and analyzed, and the interference signal or noise is filtered out by the filter circuit to ensure the signal quality. The weighing sensor 2 interface adopts the snap-on connector in the prior art, which is easy to plug and unplug.
[0025] Specifically, the number of channels of the operational amplifier circuit matches the number of settings of the weighing sensor 2 module. After the signal is amplified, the sampling accuracy can reach 50mg (high accuracy).
[0026] Specifically, the filter circuit adopts an RC filter circuit, and the RC parameters are set according to actual test results and sampling accuracy.
[0027] Specifically, the AD sampling circuit: outputs the reliable signal after being filtered by the filter circuit to the AD sampling circuit, which converts the analog signal into a digital signal and sets the sampling rate and sampling speed. The AD sampling circuit is powered by a reference power supply circuit to ensure its sampling accuracy. The digital signal sampled by the AD sampling circuit is transmitted to the MCU microprocessor through SPI communication for analysis and processing. The MCU microprocessor transmits the analyzed and processed data to the monitoring and display circuit through the RS232 communication circuit for monitoring and display. The sampling AD chip adopts a multi-channel AD, with but not limited to 4 channels; it can realize real-time monitoring of 2 channels of each weighing sensor, while reducing costs, and the sampling accuracy can reach 50mg (high precision); Specifically, the MCU microprocessor adopts the STM32FM series and supports CAN communication, 485 communication, or RS323 communication. In this embodiment, RS232 communication is adopted.
[0028] Specifically, the monitoring display unit module adopts a liquid crystal display screen; it correspondingly displays the current status of the sample or reagent. Embodiment 2
[0029] Based on the first embodiment, Figure 1 , Figure 2 , Figure 3As shown, the weighing sensor 2 modules are listed as 1-4; the weighing sensor 2 module includes a tray 1, a weighing sensor 2, a weighing table 3, and a positioning groove. A placement area is set on each tray 1, and a weighing sensor 2 is installed below the placement area. Above the weighing sensor 2 is a weighing table 3, which is used to place sample bottles or reagent bottles. Each weighing sensor 2 module is independent and adapted to weighing sensors 2 of different models and ranges to weigh samples or reagents of different weights; the preferred weighing sensor 2 is a strain sensor. The weighing sensor 2 module can be set as multiple modules, and the package block is not limited to 4.
[0030] Specifically, Figure 1 , Figure 2 As shown, four weighing sensor 2 modules correspond to four weighing sensor 2 interfaces. The connector used by the weighing sensor 2 interface is a snap-on connector, which is convenient for plugging and maintenance; and the weighing sensor 2 interface adopts a universal connector interface, which is small in size and low in cost. The weighing sensor 2 interface of the weighing sensor 2 module is connected to the MCU microprocessor through an operational amplifier circuit, a filter circuit, and an AD sampling circuit. The operational amplifier circuit, the filter circuit, the AD sampling circuit, the MCU microprocessor, the communication interface circuit, and the monitoring display circuit are powered by a multi-stage power supply circuit.
[0031] Specifically, the power supply adopts a low-voltage DC single power supply +24V, which is converted to +5V through a DCDC voltage-stabilized power supply conversion chip, and is used to power an LDO linear power supply chip and converted to 3.3V; the LDO linear power supply chip has the characteristics of low noise and low power consumption; it meets and improves the sampling accuracy. The reference power supply of the reference power supply circuit used in this example is TI's REF5050, which has the characteristics of small size, low noise, extremely low temperature drift, high-precision voltage reference, and low cost.
[0032] Specifically, the weighing signal of the weighing sensor 2 is a weak signal, and the weighing signal is amplified to a signal that can be collected and analyzed through the operational amplifier circuit; the type selected in the operational amplifier circuit is a high-precision operational amplifier from TI or ADI. The OPA325 chip of TI used in this example has the characteristics of small size, low noise, low power consumption, high precision, and low cost.
[0033] Specifically, the weighing signal is amplified by the operational amplifier circuit to a signal that can be collected and analyzed, and then is sampled by the AD sampling chip of the AD sampling circuit through the filter circuit; the filter circuit adopts a low-cost RC filter circuit. The RC filter circuit calculates the adaptation parameters according to the sampled signal. The RC filter circuit has the characteristics of simplicity and low cost.
[0034] Specifically, the AD sampling chip of the AD sampling circuit is powered by a reference power supply circuit of a multi-stage power supply circuit to ensure the power supply stability and accuracy of the AD sampling power supply. The AD sampling chip is an analog-to-digital conversion chip of TI or ADI. The ADS114S08 chip of TI used in this example has the characteristics of multi-channel, high sampling rate, high sampling accuracy, etc.
[0035] Specifically, after AD sampling, the data is transmitted to the MCU microprocessor for analysis and processing. The MCU microprocessor uses the STM32F4 series chip of ST Company. The AD sampling chip and the MCU microprocessor use the SPI communication mode. SPI communication has the advantages of simple communication, full-duplex communication, high data transmission rate, and strong signal integrity. The MCU microprocessor is not limited to the STM32F4 series chip of ST Company. Specifically, the RS232 communication interface circuit uses the MAX3232 communication chip of ADI, which has the advantages of low power consumption and low cost. The RS232 communication chip converts the output data from the MCU microprocessor into RS232 format through TTL format, improving the transmission quality and anti-interference of the signal data. The RS232 communication chip transmits the output data from the MCU microprocessor to the monitoring and display unit module (used to monitor and display the status of the sample volume or reagent volume); when the residual amount of the displayed sample or reagent is lower than the set threshold, the monitoring and display unit module displays an alarm. Embodiment 3
[0036] Based on the first embodiment, Figure 1-Figure 4 As shown, the AD sampling circuit adopts the ADS114S08 sampling chip, and the sampling port of the ADS114S08 sampling chip is connected to several groups of weighing sensors, operational amplifier circuits, and filtering circuits connected in series; the output ends of the weighing sensors are connected to the input ends of the operational chip in the operational amplifier circuit through two resistors, one of the input ends of the operational chip is connected to the positive power supply terminal of the operational chip +5V power supply through a resistor and a capacitor, and the GND pin of the operational chip is grounded. A capacitor and a resistor are connected in parallel between the other input end and the output end of the operational chip, and the output end of the operational chip is connected to the sampling port of the ADS114S08 sampling chip through the resistor and capacitor connected in series in the filtering circuit.
[0037] The REFP0 port of the ADS114S08 sampling chip is connected to the REF5050 power chip of the reference power circuit, and the VOUT end of the REF5050 power chip is connected to the ADS114S08 sampling chip. The VOUT end of the REF5050 power chip is also grounded through capacitor C51 and series-connected resistor R51 and capacitor C52. The power end of the REF5050 power chip is connected to +12V, and a branch connection is grounded through capacitor C53.
[0038] The ADS114S08 sampling chip is connected to the STM32F407ZET6 chip of the MCU microprocessor, the USART_TX port and USART_RX port of the STM32F407ZET6 chip are connected to the SP3232 chip of the RS232 communication interface circuit, and the TxOUT port and port of the SP3232 chip are connected to the P interface in the monitoring display unit interface.
[0039] The power supply circuit includes a J5 interface connected to an external power supply. The output end of the J5 interface is connected to a diode D1 and outputs a +24V voltage. A capacitor C70 is connected in parallel at both ends of the diode D1 and is grounded through one end of a capacitor C71. The other end of the capacitor C70 is connected to the input end of the K7812-1000R3 chip through a resistor F1. The input end of the 7812-1000R3 chip is also grounded through a capacitor C71. The output end of the K7812-1000R3 chip outputs a +12V voltage. The output end of the K7812-1000R3 chip is connected to the input end of the K7805-500R3 chip, the output end of the K7805-500R3 chip is connected to the input end of the LM1117MP-3.3 / TR chip, the output end of the K7805-500R3 chip outputs a +5V voltage and is grounded through capacitor C73; the output end of the LM1117MP-3.3 / TR chip outputs a 3.3V voltage and is grounded through capacitor C74. Embodiment 4
[0040] Based on the first embodiment, Figure 1 , Figure 2 , Figure 3 As shown, a real-time online high-precision detection method for residual reagents comprises the following steps: Step 1, placing the reagent container to be tested on the weighing platform 3 of the corresponding weighing sensor 2 module; Step 2, obtaining the weight of the reagent container to be tested on the weighing platform 3 in real time through the weighing sensor 2 in the weighing sensor 2 module; Step 3, the pressure operational amplifier circuit amplifies the signal of the weighing sensor 2 of the reagent container to be detected obtained on the weighing platform 3, and then filters out the interference signal or noise through the filter circuit, and converts the filtered signal into digital form through the AD sampling circuit, and inputs the converted digital signal into the MCU microprocessor for sampling, and the MCU microprocessor obtains the sampled detection signal; Step 4: The sampled detection signal obtained by the MCU microprocessor is transmitted to the monitoring and display circuit through the communication interface circuit, and displayed through the monitoring and display circuit. Embodiment 5
[0041] Based on Example 2 or Example 4, a real-time online high-precision detection method for reagent residual amount also includes, after step 3, the MCU microprocessor compares the acquired sampled detection signal with a preset threshold value, and issues an alarm or prompts to shut down due to insufficient residual amount according to the triggering residual threshold channel. Embodiment 6
[0042] Based on the second embodiment or the third embodiment or the fourth embodiment, all weighing added values, including the weighing added values of the empty test agent containers, are cleared before real-time monitoring, and only the net value of the sample or reagent is monitored in real time.
[0043] Working principle: A real-time online high-precision detection system and method for residual reagents can accurately monitor the use of consumables such as samples or reagents online, so that users can clearly understand in real time whether the current sample volume and reagent volume are sufficient, and how long the remaining sample or reagent will last. The present invention can monitor the residual amount of samples or reagents online; high-precision monitoring is also suitable for applications with small sample or reagent volume and light weight; it is suitable for multiple types of weighing sensors 2, realizing multi-channel monitoring, high efficiency and low cost.
[0044] The above specific implementation methods are specific support for the scheme ideas proposed in the present invention, and cannot be used to limit the protection scope of the present invention. Any equivalent changes or equivalent modifications made on the basis of this technical scheme in accordance with the technical ideas proposed in the present invention still fall within the scope of protection of the technical scheme of the present invention.
Claims
1. A real-time high-precision detection system for residual reagents, characterized in that: include: A weighing sensor module, the weighing sensor module comprising a tray for testing, the tray being provided with a placement area, the placement area being provided with a weighing platform, a weighing sensor being provided between the weighing platform and the placement area of the tray, the weighing platform being provided with a positioning groove for positioning a reagent container to be tested; The weighing sensor is connected to the microprocessor through an operational amplifier circuit, a filter circuit, and an AD sampling circuit, and the microprocessor is electrically connected to a monitoring and display circuit through a communication interface circuit.
2. The real-time online high-precision detection system for residual reagent amount according to claim 1 is characterized in that: The weighing sensor is connected to the input end of the operational amplifier circuit through the weighing sensor interface, the output end of the operational amplifier circuit is connected to the input end of the filter circuit, the output end of the filter circuit is connected to the input end of the AD sampling circuit, the microprocessor is an MCU microprocessor, and the output end of the AD sampling circuit is connected to the I / O interface of the MCU microprocessor.
3. The real-time online high-precision detection system for residual reagent amount according to claim 2 is characterized in that: It also includes a multi-stage power supply circuit that supplies power to the weighing sensor module, operational amplifier circuit, filter circuit, AD sampling circuit, MCU microprocessor, communication interface circuit, and monitoring display circuit.
4. The real-time online high-precision detection system for residual reagent according to claim 3 is characterized in that: The multi-stage power supply circuit includes a power supply module and a reference power supply circuit electrically connected to the power supply module. The power supply module adopts a +24V low-voltage DC single power supply. The power supply module converts the power into +5V power through a DC-DC regulated power supply conversion chip. The DC-DC regulated power supply conversion chip is used to power the LDO linear power supply chip and is converted into 3.3V power by the LDO linear power supply chip.
5. The real-time online high-precision detection system for residual reagent amount according to claim 4 is characterized in that: The number of channels of the operational amplifier circuit matches the number of settings of the weighing sensor modules.
6. The real-time online high-precision detection system for residual reagent according to claim 5, characterized in that: The filter circuit adopts an RC filter circuit.
7. The real-time online high-precision detection system for residual reagent amount according to claim 6 is characterized in that: The MCU microprocessor adopts the STM32FM series and supports CAN communication, 485 communication, or RS323 communication.
8. The real-time online high-precision detection system for residual reagent amount according to claim 6, characterized in that: The AD sampling circuit adopts the ADS114S08 sampling chip, and the sampling port of the ADS114S08 sampling chip is connected to several groups of weighing sensors, operational amplifier circuits, and filter circuits connected in series; the output end of the weighing sensor is connected to the input end of the operational chip in the operational amplifier circuit through two resistors, one of the input ends of the operational chip is connected to the positive power supply terminal of the operational chip +5V power supply through a resistor and a capacitor, and the GND pin of the operational chip is grounded. A capacitor and a resistor are connected in parallel between the other input end and the output end of the operational chip, and the output end of the operational chip is connected to the sampling port of the ADS114S08 sampling chip through a resistor and a capacitor connected in series in the filter circuit; The REFP0 port of the ADS114S08 sampling chip is connected to the REF5050 power chip of the reference power circuit, and the VOUT end of the REF5050 power chip is connected to the ADS114S08 sampling chip. The VOUT end of the REF5050 power chip is also grounded through capacitor C51 and a series resistor R51 and capacitor C52. The power end of the REF5050 power chip is connected to +12V, and the branch connection is grounded through capacitor C53. The ADS114S08 sampling chip is connected to the STM32F407ZET6 chip of the MCU microprocessor, the USART_TX port and USART_RX port of the STM32F407ZET6 chip are connected to the SP3232 chip of the RS232 communication interface circuit, and the TxOUT port and port of the SP3232 chip are connected to the P interface in the monitoring display unit interface; The power supply circuit includes a J5 interface connected to an external power supply. The output end of the J5 interface is connected to a diode D1 and outputs a +24V voltage. Capacitor C70 is connected in parallel at both ends of the diode D1 and is grounded through one end of a capacitor C71. The other end of the capacitor C70 is connected to the input end of the K7812-1000R3 chip through a resistor F1. The input end of the K7812-1000R3 chip is also grounded through a capacitor C71. The output end of the K7812-1000R3 chip outputs a +12V voltage. The output end of the K7812-1000R3 chip is connected to the input end of the K7805-500R3 chip, the output end of the K7805-500R3 chip is connected to the input end of the LM1117MP-3.3 / TR chip, the output end of the K7805-500R3 chip outputs a +5V voltage and is grounded through capacitor C73; the output end of the LM1117MP-3.3 / TR chip outputs a 3.3V voltage and is grounded through capacitor C74.
9. A real-time high-precision detection method for residual reagents, characterized in that: The method is implemented by using a real-time online high-precision detection system for residual reagent according to any one of claims 1 to 8, comprising the following steps: Step 1: Place the reagent container to be tested on the weighing table of the corresponding weighing sensor module; Step 2, obtaining the weight of the reagent container to be tested on the weighing table in real time through the weighing sensor in the weighing sensor module; Step 3, the pressure operational amplifier circuit amplifies the signal of the weighing sensor of the reagent container to be detected obtained on the weighing table, and then filters out the interference signal or noise through the filter circuit, and converts the filtered signal into digital form through the AD sampling circuit, and inputs the converted digital signal into the MCU microprocessor for sampling, and the MCU microprocessor obtains the sampled detection signal; Step 4: The sampled detection signal obtained by the MCU microprocessor is transmitted to the monitoring and display circuit through the communication interface circuit, and displayed through the monitoring and display circuit.
10. The real-time online high-precision detection method for residual reagent according to claim 9, characterized in that: After step 3, the MCU microprocessor compares the acquired sampled detection signal with a preset threshold value, and issues an alarm or prompts a shutdown due to insufficient margin according to the trigger margin threshold channel; And / or, all weighing added values, including empty test agent containers, are cleared before real-time monitoring, and only the net value of the sample or reagent is monitored in real time.
Citation Information
Cited By
Feedback circuit for improving measurement accuracy of strain sensor
CN119787995A
Feedback Circuit for Improving the Measurement Accuracy of Strain Sensors
CN119787995B