A heparin sodium raw material leak detection device

Abstract

The present invention discloses a heparin sodium raw material leak detection device, which specifically relates to the field of testing the sealing performance of heparin sodium raw materials under a vacuum environment, including a raw material storage cylinder, wherein the heparin sodium raw material is stored inside the raw material storage cylinder, the top of the raw material storage cylinder is sealedly connected with a raw material cylinder cover, the bottom of the raw material cylinder cover is installed with a supporting piston ring, the supporting piston ring is piston-shaped and slidingly connected to the inner cavity of the raw material storage cylinder, a disc-shaped airbag part is fixedly installed on the top of the inner cavity of the raw material cylinder cover, and the inner cavity of the disc-shaped airbag part is filled with fluorescent gas for detecting sealing performance; a round hole is opened in a through-shaped manner on the top of the raw material cylinder cover. A puncture needle penetrates the prefabricated isolation membrane and the two-layer disc-shaped airbag part, at which time the fluorescent gas in the disc-shaped airbag part leaks out, and the fluorescent gas between the raw material cylinder cover and the supporting piston ring is used to detect the sealing effect of the gap of the connecting thread tooth groove between the raw material storage cylinder and the raw material cylinder cover.

Description

Technical Field

[0001] The invention relates to the technical field of testing the sealing performance of heparin sodium raw materials under a vacuum environment, and more specifically, to a heparin sodium raw material leakage detection device. Background Art

[0002] The raw material of sodium heparin usually exists in the form of powder. Sodium heparin is a polysaccharide extracted and purified from animal tissues (such as pig intestinal mucosa or cow lung). The purified sodium heparin is usually processed into dry powder, which is easier to store, transport and prepare into different drug dosage forms, such as injection. Before use, sodium heparin in powder form is usually dissolved in an appropriate solvent to prepare the final drug preparation.

[0003] If sodium heparin is not sealed well, a series of problems will occur. First, poor sealing will cause the drug to become damp and deteriorate. Sodium heparin is sensitive to moisture and impurities in the air. Poor sealing will change its physical and chemical properties and affect the efficacy. Secondly, poor sealing will increase the risk of microbial contamination. Incompletely sealed packaging may become an invasion route for bacteria, mold and other microorganisms, leading to drug contamination and endangering patient health. Thirdly, poor sealing will cause the degradation of the active ingredients of the drug. Sodium heparin may undergo degradation reactions when exposed to air and light, reducing the effectiveness and safety of the drug. In addition, poor sealing will also lead to decreased stability of the drug, shortened shelf life of the drug, and even failure during storage and transportation. Furthermore, poor sealing will affect the use and therapeutic effects of the drug. Patients using contaminated or expired sodium heparin may not achieve the expected therapeutic effect, and in severe cases may cause adverse reactions or medical accidents. Therefore, ensuring good sealing of sodium heparin is crucial to ensuring the quality, safety and efficacy of the drug. Summary of the invention

[0004] In order to overcome the above-mentioned defects of the prior art, an embodiment of the present invention provides a sodium heparin raw material leak detection device, in which a puncture needle penetrates the prefabricated isolation membrane and the two-layer disc-shaped airbag portion. At this time, the fluorescent gas in the disc-shaped airbag portion leaks out, and the fluorescent gas between the raw material barrel cover and the supporting piston ring is used to detect the sealing effect of the gap of the connecting thread groove between the raw material storage barrel and the raw material barrel cover, so as to solve the problems raised in the above-mentioned background technology.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a heparin sodium raw material leak detection device, comprising a raw material storage cylinder, wherein the heparin sodium raw material is stored inside the raw material storage cylinder, the top of the raw material storage cylinder is sealedly connected with a raw material cylinder cover, the bottom of the raw material cylinder cover is installed with a supporting piston ring, the supporting piston ring is piston-shaped and slidably connected to the inner cavity of the raw material storage cylinder, a disc-shaped airbag portion is fixedly installed on the top of the inner cavity of the raw material cylinder cover, and the inner cavity of the disc-shaped airbag portion is filled with fluorescent gas for detecting sealing;

[0006] The top of the raw material barrel cover is provided with a round hole in a through shape, an extended observation barrel is fixedly installed at the round hole on the top of the raw material barrel cover, an airbag section adjustment section is fixedly installed on the top of the extended observation barrel, and a puncture needle for puncturing the disc-shaped airbag part is fixedly installed on the top of the inner cavity of the airbag section adjustment section;

[0007] The raw material storage tube, the raw material tube cover, the extended observation tube and the air bag section adjustment section are made of transparent materials.

[0008] In a preferred embodiment, the top outer wall of the raw material storage barrel and the inner wall of the raw material barrel cover are provided with mutually meshing engaging thread grooves, and the raw material storage barrel and the raw material barrel cover are threadedly connected via the engaging thread grooves.

[0009] In a preferred embodiment, a puncture needle positioning cylinder is fixedly installed on the top of the inner cavity of the airbag section adjustment section, a disc-shaped puncture needle limiting ring is fixedly installed between the airbag section adjustment section and the extended observation tube, a hole is provided in the middle of the puncture needle limiting ring, the puncture needle positioning cylinder passes through the hole in the middle of the puncture needle limiting ring, and the puncture needle is installed at the bottom of the puncture needle positioning cylinder;

[0010] A prefabricated hole-expanding block is fixedly installed between the puncture needle and the puncture needle positioning cylinder, and the prefabricated hole-expanding block is fixedly installed at the bottom of the puncture needle positioning cylinder. A plurality of strip-shaped positioning elastic ropes are fixedly installed between the puncture needle limiting ring and the prefabricated hole-expanding block, and the plurality of strip-shaped positioning elastic ropes are distributed in sequence in a circular shape and at equal intervals.

[0011] In a preferred embodiment, the circular hole in the top of the raw material barrel cover is a circular prefabricated notch, and a prefabricated isolation membrane is fixedly installed in the inner cavity of the circular prefabricated notch, and the prefabricated isolation membrane is arranged at the bottom of the puncture needle.

[0012] In a preferred embodiment, the inner cavity of the disc-shaped airbag portion is fixedly installed with a plurality of support shafts, the support shafts are fixedly installed on the top of the inner cavity of the raw material barrel cover, the bottom of the support shaft is installed with a bolt connection seat, the bottom of the support shaft is threadedly connected with a buffer-type telescopic rod through the bolt connection seat, the support-type piston ring includes a piston and a support disc, the piston is fixedly installed on the outer periphery of the support disc in a sealing manner, and the bottom end of the buffer-type telescopic rod is fixedly installed on the top of the support-type piston ring;

[0013] The buffer type telescopic rod is a hydraulic telescopic rod.

[0014] In a preferred embodiment, a limited card cover is fixedly installed at the bottom of the support disc of the support piston ring, and the diameter of the limited card cover is larger than the inner diameter of the raw material storage cylinder under normal conditions;

[0015] A plurality of arc-shaped positioning rings are fixedly connected between the supporting piston ring and the limiting card cover, and the plurality of arc-shaped positioning rings are arranged in a circular shape with equal distances and distributed in sequence.

[0016] In a preferred embodiment, the middle portion of the arc-shaped positioning ring is concave, and a plurality of annular positioning elastic sheets are sleeved on the concave portions of the middle portions of the arc-shaped positioning rings;

[0017] The interior of the annular positioning elastic sheet is hollow, and an annular positioning elastic rope is fixedly mounted on the outer wall of the annular positioning elastic sheet.

[0018] In a preferred embodiment, a sealing strip structure for sealing is installed at the outer wall of the disc-shaped airbag portion, and the sealing strip structure includes a rubber sealing ring layer 1, a rubber sealing ring layer 2, a rubber support block, a positioning support rod and a prefabricated connecting ring, and the prefabricated connecting ring is fixedly installed on the outer wall of the disc-shaped airbag portion, and the number of the rubber support blocks is set to at least two groups, and the number of the rubber support blocks is consistent with the number of the prefabricated connecting rings, and the rubber support blocks are inserted into the inner cavity of the rubber sealing ring layer 1 and the rubber sealing ring layer 2 to form a supporting surface, and the supporting surface is used to abut against the inner wall of the raw material storage cylinder;

[0019] The positioning support rod is installed between two groups of rubber support blocks.

[0020] In a preferred embodiment, a positioning type central shaft is fixedly installed at the bottom of the inner cavity of the raw material storage cylinder, a spiral segment 1 is fixedly installed on the outer wall of the positioning type central shaft, a material storage type spiral plate is installed on the outer wall of the positioning type central shaft, a spiral segment 2 is fixedly installed at the inner edge of the material storage type spiral plate, and the spiral segment 2 is meshed with the spiral segment 1;

[0021] A semicircular extension cover is fixedly installed on the outer edge of the storage type spiral plate, wherein the heparin sodium raw material is filled between the multiple layers of the storage type spiral plates;

[0022] A spherical anti-collision top block is installed on the top of the positioning type center shaft rod through bolts.

[0023] In a preferred embodiment, the fluorescent gas includes fluorescent gas and ammonia;

[0024] A humidity detection system is installed at the bottom of the position-limiting card cover, and the humidity detection system includes a microcontroller, a digital humidity sensor, connecting wires, an LED lamp, a breadboard and a resistor.

[0025] Technical effects and advantages of the present invention:

[0026] Press the airbag section adjustment section, and pierce the prefabricated isolation membrane and the two-layer disc-shaped airbag part through the puncture needle. At this time, the fluorescent gas in the disc-shaped airbag part leaks out. The fluorescent gas between the raw material barrel cover and the supporting piston ring is used to detect the sealing effect of the gap between the connecting thread groove between the raw material storage barrel and the raw material barrel cover. Use a fluorescent detector or ultraviolet lamp to scan the raw material storage barrel and the raw material barrel cover. The fluorescent gas will overflow through the bottle wall or the poorly sealed place at the leakage point. The detector or ultraviolet lamp can detect these fluorescent signals, which improves the convenience of detecting the vacuum sealing of a large number of raw material storage barrels;

[0027] After the storage of the heparin sodium raw material is completed, the raw material cylinder cover is threadedly connected to the top of the raw material storage cylinder through the connecting thread groove, wherein the limiting card cover, the supporting piston ring and the rubber support block form a three-layer sealing state from bottom to top, and the probability of air leakage is reduced through the multi-layer sealing method;

[0028] By using it in conjunction with the humidity detection system, when leakage occurs, the sodium heparin raw material will be directly exposed to moisture. On the one hand, it is used to prevent the sodium heparin raw material that does not meet the sealing standards from being reused by illegal vendors. On the other hand, it is used to detect the sealing effect of the supporting piston ring and the limiting card cover. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0030] Figure 2 It is a structural exploded view of the raw material storage cylinder and the raw material cylinder cover of the present invention.

[0031] Figure 3 It is a structural cross-sectional view of the present invention.

[0032] Figure 4 For the present invention Figure 3 A-section structure enlarged view.

[0033] Figure 5 For the present invention Figure 3 Enlarged view of the structure of part B.

[0034] Figure 6 It is a structural cross-sectional view of the raw material cylinder cover of the present invention.

[0035] Figure 7 For the present invention Figure 6 Enlarged view of the C structure.

[0036] Figure 8 For the present invention Figure 6 Enlarged view of the D structure.

[0037] Fig. 9 For the present invention Figure 6 Enlarged view of the E part structure.

[0038] The accompanying drawings are marked as: 1 raw material storage cylinder, 2 raw material cylinder cover, 3 support type piston ring, 4 disc-shaped airbag part, 5 extension type observation cylinder, 6 airbag section adjustment section, 7 puncture needle, 8 connecting type threaded tooth groove, 9 puncture needle positioning cylinder, 10 puncture needle limiting ring, 11 prefabricated expansion block, 12 strip positioning elastic rope, 13 prefabricated isolation membrane, 14 circular prefabricated notch, 15 buffer type telescopic rod, 16 bolt connection seat, 17 annular positioning elastic sheet, 18 limiting card cover, 19 arc positioning ring, 20 annular positioning elastic rope, 21 rubber sealing ring layer one, 22 rubber sealing ring layer two, 23 rubber support block, 24 positioning support rod, 25 prefabricated connecting ring, 26 positioning center shaft rod, 27 spiral segment one, 28 storage type spiral plate, 29 spiral segment two, 30 semicircular extension cover, 31 spherical anti-collision top block. DETAILED DESCRIPTION

[0039] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0040] Refer to the instruction manual Figure 1-9A sodium heparin raw material leak detection device according to an embodiment of the present invention comprises a raw material storage cylinder 1, wherein the sodium heparin raw material is stored inside the raw material storage cylinder 1, the top of the raw material storage cylinder 1 is sealedly connected with a raw material cylinder cover 2, the bottom of the raw material cylinder cover 2 is installed with a supporting piston ring 3, the supporting piston ring 3 is piston-shaped and slidably connected to the inner cavity of the raw material storage cylinder 1, a disc-shaped airbag portion 4 is fixedly installed on the top of the inner cavity of the raw material cylinder cover 2, and the inner cavity of the disc-shaped airbag portion 4 is filled with fluorescent gas for detecting sealing; a circular hole is opened in a through shape on the top of the raw material cylinder cover 2, an extended observation cylinder 5 is fixedly installed at the circular hole on the top of the raw material cylinder cover 2, an airbag section adjustment section 6 is fixedly installed on the top of the extended observation cylinder 5, and a puncture needle 7 for puncturing the disc-shaped airbag portion 4 is fixedly installed on the top of the inner cavity of the airbag section adjustment section 6; the raw material storage cylinder 1, the raw material cylinder cover 2, the extended observation cylinder 5 and the airbag section adjustment section 6 are made of transparent materials.

[0041] The top outer wall of the raw material storage cylinder 1 and the inner wall of the raw material cylinder cover 2 are provided with mutually meshing connecting thread grooves 8, the raw material storage cylinder 1 and the raw material cylinder cover 2 are threadedly connected through the connecting thread grooves 8, a puncture needle positioning cylinder 9 is fixedly installed on the top of the inner cavity of the airbag section adjustment section 6, a disc-shaped puncture needle limiting ring 10 is fixedly installed between the airbag section adjustment section 6 and the extended observation cylinder 5, a hole is provided in the middle of the puncture needle limiting ring 10, the puncture needle positioning cylinder 9 passes through the hole in the middle of the puncture needle limiting ring 10, and the puncture needle 7 is installed at the bottom of the puncture needle positioning cylinder 9 A prefabricated hole-expanding block 11 is fixedly installed between the puncture needle 7 and the puncture needle positioning cylinder 9, and the prefabricated hole-expanding block 11 is fixedly installed at the bottom of the puncture needle positioning cylinder 9. A plurality of strip-shaped positioning elastic ropes 12 are fixedly installed between the puncture needle limiting ring 10 and the prefabricated hole-expanding block 11. The plurality of strip-shaped positioning elastic ropes 12 are arranged in a circular shape and are equidistantly distributed in sequence. The circular hole opened in a through-shaped manner on the top of the raw material cylinder cover 2 is a circular prefabricated notch 14. A prefabricated isolation membrane 13 is fixedly installed in the inner cavity of the circular prefabricated notch 14, and the prefabricated isolation membrane 13 is arranged at the bottom of the puncture needle 7.

[0042] A plurality of support shafts are fixedly installed in the inner cavity of the disc-shaped airbag portion 4, the support shafts are fixedly installed on the top of the inner cavity of the raw material barrel cover 2, a bolt connection seat 16 is installed at the bottom of the support shaft, a buffer-type telescopic rod 15 is threadedly connected to the bottom of the support shaft through the bolt connection seat 16, the support-type piston ring 3 includes a piston and a support disc, the piston is fixedly installed in a sealing manner on the outer periphery of the support disc, and the bottom end of the buffer-type telescopic rod 15 is fixedly installed on the top of the support-type piston ring 3; wherein the buffer-type telescopic rod 15 is a hydraulic telescopic rod.

[0043] A limiting card cover 18 is fixedly installed at the bottom of the supporting disc of the supporting piston ring 3. Under normal circumstances, the diameter of the limiting card cover 18 is larger than the inner diameter of the raw material storage cylinder 1. A plurality of arc-shaped positioning rings 19 are fixedly connected between the supporting piston ring 3 and the limiting card cover 18. The plurality of arc-shaped positioning rings 19 are arranged in a circular shape and are equidistantly distributed in sequence. The middle part of the arc-shaped positioning ring 19 is concave. An annular positioning elastic sheet 17 is sleeved on the concave part of the middle part of the plurality of arc-shaped positioning rings 19. The interior of the annular positioning elastic sheet 17 is hollow. An annular positioning elastic rope 20 is fixedly installed on the outer wall of the annular positioning elastic sheet 17.

[0044] A sealing strip structure is installed on the outer wall of the disc-shaped airbag portion 4, and the sealing strip structure includes a rubber sealing ring layer 1 21, a rubber sealing ring layer 22, a rubber support block 23, a positioning support rod 24 and a prefabricated connecting ring 25. The prefabricated connecting ring 25 is fixedly installed on the outer wall of the disc-shaped airbag portion 4. The number of rubber support blocks 23 is set to at least two groups, and the number of rubber support blocks 23 is consistent with the number of prefabricated connecting rings 25. The rubber support blocks 23 are inserted into the inner cavity of the rubber sealing ring layer 1 21 and the rubber sealing ring layer 22 to form a support surface, and the support surface is used to abut against the inner wall of the raw material storage cylinder 1; the positioning support rod 24 is installed between the two groups of rubber support blocks 23.

[0045] A positioning type central shaft 26 is fixedly installed at the bottom of the inner cavity of the raw material storage cylinder 1, a spiral segment 1 27 is fixedly installed on the outer wall of the positioning type central shaft 26, a storage type spiral plate 28 is installed on the outer wall of the positioning type central shaft 26, a spiral segment 29 is fixedly installed at the inner edge of the storage type spiral plate 28, and the spiral segment 29 and the spiral segment 1 27 are meshed with each other; a semicircular extension cover 30 is fixedly installed at the outer edge of the storage type spiral plate 28, wherein the heparin sodium raw material is filled between the multiple layers of the storage type spiral plates 28.

[0046] As a further solution, the fluorescent gas includes fluorescent gas and ammonia; a humidity detection system is installed at the bottom of the limit-type card cover 18, and the humidity detection system includes a microcontroller, a digital humidity sensor, a connecting wire, an LED lamp with adjustable brightness, a breadboard and necessary resistors. When connecting, first connect the digital humidity sensor to the microcontroller, and write a program to read the humidity data provided by the sensor, then set a threshold in the program, and trigger an alarm when the humidity exceeds the set value. Finally, the alarm function is realized by controlling the brightness or flashing of the LED lamp, so that the LED lamp sends an obvious warning signal when the humidity is too high. After completion, install the system and ensure that the sensor can accurately measure the humidity and ensure that the LED lamp can respond to the alarm signal normally;

[0047] The microcontroller, as the main control unit of the system, is responsible for receiving humidity data from the sensor and triggering corresponding alarm operations according to the set threshold value; digital humidity sensor (such as DHT series sensor): used to measure the humidity level in the environment and convert the humidity data into digital signals for the microcontroller to read and process; connecting wires (such as DuPont wires): used to connect the circuits between the microcontroller and the humidity sensor to achieve data transmission and communication; LED lights with adjustable brightness: as an alarm indicator, depending on whether the humidity exceeds the set threshold, the brightness of the LED lights will change or flash to remind the user of excessive humidity; breadboard: used to temporarily connect circuits and components, convenient for quick construction and debugging of prototypes of humidity detection systems; resistors: can be used in current limiting or voltage dividing circuits to ensure that sensors and LED lights can work properly and protect the microcontroller from interference or overload of the circuit. In addition, the system can be powered by batteries.

[0048] Working principle: In actual use, the sodium heparin raw material is placed in the raw material storage cylinder 1, the storage type spiral plate 28 and the semicircular extension cover 30 are threadedly connected to the outer wall of the positioning type center shaft 26 through the spiral section 29, and the sodium heparin raw material is stored between the multi-layer storage type spiral plates 28. The top of the positioning type center shaft 26 is bolted with a spherical anti-collision top block 31, which is used to prevent the sodium heparin raw material from splashing up and down in the inner cavity of the raw material storage cylinder 1 during transportation or use, and plays the role of clamping the sodium heparin raw material powder;

[0049] After the storage of the heparin sodium raw material is completed, the raw material barrel cover 2 is threadedly connected to the top of the raw material storage barrel 1 through the connecting thread groove 8, wherein the limiting card cover 18, the supporting piston ring 3 and the rubber support block 23 form a three-layer sealing state from bottom to top, wherein the rubber sealing ring layer 1 21, the rubber sealing ring layer 22 and the rubber support block 23 cooperate to form a sealing state of the seal structure, the supporting piston ring 3 is a piston-shaped sealing structure simulating a "syringe", the limiting card cover 18 uses the structure of the bottom edge to form a sealing ring state, and the buffering telescopic rod 15 provides a buffer space for the limiting card cover 18 to prevent the gas expansion in the raw material storage barrel 1, and directly squeeze and burst the raw material barrel cover 2;

[0050] When detecting the vacuum sealing environment formed between the raw material storage barrel 1 and the raw material barrel cover 2, first press the airbag section adjustment section 6 so that the puncture needle 7 at the bottom of the airbag section adjustment section 6 penetrates the prefabricated isolation membrane 13 and the two-layer disc-shaped airbag part 4. At this time, the fluorescent gas in the disc-shaped airbag part 4 leaks out and diffuses between the raw material barrel cover 2 and the supporting piston ring 3. When the raw material storage barrel 1 and the raw material barrel cover 2 are installed through the connecting thread groove 8, the fluorescent gas between the raw material barrel cover 2 and the supporting piston ring 3 is used to detect the sealing effect of the gap of the connecting thread groove 8 between the raw material storage barrel 1 and the raw material barrel cover 2. Use a fluorescence detector or an ultraviolet lamp to scan the raw material storage barrel 1 and the raw material barrel cover 2. The fluorescent gas will overflow through the bottle wall or the poorly sealed place at the leakage point, and the detector or ultraviolet lamp can detect these fluorescent signals;

[0051] The scheme of using fluorescent gas to detect the vacuum sealing effect of the raw material storage cylinder 1 and the raw material cylinder cover 2 also includes a detection method, which is used in conjunction with a humidity detection system. Since the fluorescent gas includes fluorescent gas and ammonia, ammonia reacts with acidic substances (such as heparin sodium) to generate salt (such as ammonium chloride) and water, so that the heparin sodium raw material is damp. On the one hand, it is used to prevent the heparin sodium raw material that does not meet the sealing standards from being used again by illegal vendors. On the other hand, it is used to detect the sealing effect of the supporting piston ring 3 and the limiting card cover 18. In actual use, the raw material storage cylinder 1 and the raw material cylinder cover 2 can be selected from larger tanks or smaller tanks. The smaller tank is used for transportation, and the larger tank is used for fixed-point storage.

[0052] Fluorescent gases include stable gases such as oxygen, nitrogen, helium and argon. In addition, ammonia itself is not a fluorescent gas, but it can react with certain fluorescent dyes to produce fluorescence. The mechanism of this fluorescence production is generally through the reaction of ammonia with dyes to produce amino compounds. These compounds may have fluorescent properties. Therefore, if you need to use fluorescent gases containing ammonia, you can consider selecting certain specific fluorescent dyes and conditions to produce fluorescence in the presence of ammonia. This method is generally used for specific fluorescence detection applications, such as ammonia sensors or environmental monitoring; it should also be noted that under normal circumstances, stable gases such as oxygen, nitrogen, helium and argon will not undergo obvious chemical reactions when mixed with ammonia, but in Under certain conditions, such as high temperature, high pressure or in the presence of a catalyst, the gas mixture may undergo chemical reactions. For the mixture of ammonia with other gases, the main consideration is the possible reaction of ammonia with oxygen (or other oxidants). For example, at high temperatures, ammonia and oxygen can undergo combustion reactions to produce nitrogen and water vapor. In addition, ammonia can also react with some metal or non-metal catalysts, such as reacting with oxygen to produce nitrogen oxides. In general, for the mixture of ammonia with other gases, it is necessary to consider the possible chemical reactions according to the specific situation. In engineering and experimental design, the composition and conditions of the mixed gas are usually strictly controlled to avoid unexpected adverse reactions.

[0053] The annular positioning elastic sheet 17 and the annular positioning elastic rope 20 are only used to maintain the roundness of the disc-shaped limiting cover 18 to prevent local warping and air leakage.

[0054] Finally, a few points should be explained: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, which may refer to mechanical connection or electrical connection, or internal communication between two components, or direct connection. "upper", "lower", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship may change;

[0055] Secondly: In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other;

[0056] Finally: The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A heparin sodium raw material leak detection device, comprising a raw material storage cylinder (1), wherein the heparin sodium raw material is stored inside the raw material storage cylinder (1), and the top of the raw material storage cylinder (1) is sealedly connected to a raw material cylinder cover (2), characterized in that: A supporting piston ring (3) is installed at the bottom of the raw material barrel cover (2), and the supporting piston ring (3) is slidably connected to the inner cavity of the raw material storage barrel (1) in a piston shape. A disc-shaped airbag portion (4) is fixedly installed at the top of the inner cavity of the raw material barrel cover (2), and the inner cavity of the disc-shaped airbag portion (4) is filled with fluorescent gas for detecting sealing; The top of the raw material barrel cover (2) is provided with a circular hole in a through-shaped manner, an extended observation barrel (5) is fixedly mounted at the circular hole on the top of the raw material barrel cover (2), an airbag section adjustment section (6) is fixedly mounted on the top of the extended observation barrel (5), and a puncture needle (7) for puncturing the disc-shaped airbag portion (4) is fixedly mounted on the top of the inner cavity of the airbag section adjustment section (6); The raw material storage tube (1), the raw material tube cover (2), the extended observation tube (5) and the airbag section adjustment section (6) are made of transparent material.

2. A heparin sodium raw material leak detection device according to claim 1, characterized in that: The top outer wall of the raw material storage barrel (1) and the inner wall of the raw material barrel cover (2) are provided with mutually meshing engaging threaded grooves (8), and the raw material storage barrel (1) and the raw material barrel cover (2) are threadedly connected via the engaging threaded grooves (8).

3. A heparin sodium raw material leak detection device according to claim 2, characterized in that: A puncture needle positioning cylinder (9) is fixedly mounted on the top of the inner cavity of the airbag section adjustment section (6); a disc-shaped puncture needle limiting ring (10) is fixedly mounted between the airbag section adjustment section (6) and the extended observation tube (5); a hole is provided in the middle of the puncture needle limiting ring (10); the puncture needle positioning cylinder (9) passes through the hole in the middle of the puncture needle limiting ring (10); and the puncture needle (7) is mounted at the bottom of the puncture needle positioning cylinder (9); A prefabricated hole-expanding block (11) is fixedly installed between the puncture needle (7) and the puncture needle positioning cylinder (9), and the prefabricated hole-expanding block (11) is fixedly installed at the bottom of the puncture needle positioning cylinder (9). A plurality of strip-shaped positioning elastic ropes (12) are fixedly installed between the puncture needle limiting ring (10) and the prefabricated hole-expanding block (11), and the plurality of strip-shaped positioning elastic ropes (12) are distributed in sequence in a circular shape and at equal intervals.

4. A heparin sodium raw material leak detection device according to claim 3, characterized in that: The circular hole formed in a through-hole shape at the top of the raw material barrel cover (2) is a circular prefabricated notch (14), and a prefabricated isolation membrane (13) is fixedly installed in the inner cavity of the circular prefabricated notch (14), and the prefabricated isolation membrane (13) is arranged at the bottom of the puncture needle (7).

5. A heparin sodium raw material leak detection device according to claim 4, characterized in that: The inner cavity of the disc-shaped airbag portion (4) is fixedly mounted with a plurality of support shafts, the support shafts are fixedly mounted on the top of the inner cavity of the raw material barrel cover (2), the bottom of the support shafts is mounted with a bolt connection seat (16), the bottom of the support shafts is threadedly connected with a buffer-type telescopic rod (15) via the bolt connection seat (16), the support-type piston ring (3) comprises a piston and a support disc, the piston is fixedly mounted on the outer circumference of the support disc in a sealing manner, and the bottom end of the buffer-type telescopic rod (15) is fixedly mounted on the top of the support-type piston ring (3); The buffer type telescopic rod (15) is a hydraulic telescopic rod.

6. A heparin sodium raw material leak detection device according to claim 5, characterized in that: A limiting card cover (18) is fixedly mounted on the bottom of the supporting disc of the supporting piston ring (3); under normal conditions, the diameter of the limiting card cover (18) is larger than the inner diameter of the raw material storage cylinder (1); A plurality of arc-shaped positioning rings (19) are fixedly connected between the supporting piston ring (3) and the limiting card cover (18), and the plurality of arc-shaped positioning rings (19) are arranged in a circular shape and are equidistantly distributed in sequence.

7. A heparin sodium raw material leak detection device according to claim 6, characterized in that: The middle portion of the arc-shaped positioning ring (19) is arranged in a concave shape, and a plurality of annular positioning elastic sheets (17) are sleeved on the concave portions of the middle portions of the arc-shaped positioning rings (19); The interior of the annular positioning elastic sheet (17) is hollow, and an annular positioning elastic rope (20) is fixedly mounted on the outer wall of the annular positioning elastic sheet (17).

8. A heparin sodium raw material leak detection device according to claim 7, characterized in that: A sealing strip structure for sealing is installed on the outer wall of the disc-shaped airbag portion (4), the sealing strip structure comprising a first rubber sealing ring layer (21), a second rubber sealing ring layer (22), a rubber support block (23), a positioning support rod (24) and a prefabricated connecting ring (25), the prefabricated connecting ring (25) being fixedly installed on the outer wall of the disc-shaped airbag portion (4), the number of the rubber support blocks (23) being set to at least two groups, the number of the rubber support blocks (23) being consistent with the number of the prefabricated connecting rings (25), the rubber support blocks (23) being inserted into the inner cavity of the first rubber sealing ring layer (21) and the second rubber sealing ring layer (22) to form a supporting surface, the supporting surface being used to abut against the inner wall of the raw material storage cylinder (1); The positioning support rod (24) is installed between two groups of rubber support blocks (23).

9. A heparin sodium raw material leak detection device according to claim 8, characterized in that: A positioning type central shaft (26) is fixedly mounted on the bottom of the inner cavity of the raw material storage cylinder (1), a spiral segment 1 (27) is fixedly mounted on the outer wall of the positioning type central shaft (26), a material storage type spiral plate (28) is mounted on the outer wall of the positioning type central shaft (26), a spiral segment 2 (29) is fixedly mounted on the inner edge of the material storage type spiral plate (28), and the spiral segment 2 (29) is meshed with the spiral segment 1 (27); A semicircular extension cover (30) is fixedly installed at the outer edge of the storage type spiral plate (28), wherein the heparin sodium raw material is filled between the multiple layers of the storage type spiral plate (28); A spherical anti-collision top block (31) is mounted on the top of the positioning type center shaft rod (26) via bolts.

10. A heparin sodium raw material leak detection device according to claim 9, characterized in that: The fluorescent gas includes fluorescent gas and ammonia; A humidity detection system is installed at the bottom of the position-limiting card cover (18), and the humidity detection system comprises a microcontroller, a digital humidity sensor, connecting wires, an LED lamp, a breadboard, and a resistor.

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