Traditional Chinese medicine composition for dispelling cold of gastritis and preparation method of traditional Chinese medicine composition

Abstract

The invention provides a cold-dispelling traditional Chinese medicine composition for gastritis and a preparation method thereof, and relates to the technical field of traditional Chinese medicine formulas. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials: 40 parts of rhizoma atractylodis, 40 parts of rhizoma atractylodis macrocephalae, 40 parts of cortex magnoliae officinalis, 24 parts of liquorice root, 48 parts of herba pogostemonis, 16 parts of rhizoma coptidis, 40 parts of ginger charcoal, 32 parts of fructus evodiae, 60 parts of pericarpium citri reticulatae, 28 parts of fructus amomi rotundus, 120 parts of poria cocos, 40 parts of rhizoma pinellinae praeparata, 60 parts of radix codonopsis and 72 parts of concha arcae. A cold dispelling method is combined on the common gastritis treatment mechanism of tonifying spleen and regulating qi, and clearing heat and eliminating dampness to form a new prescription for treating gastritis, the prescription adopts fourteen medicines as a prescription, the prescription is combined to achieve the effects of warming stomach and dispelling cold, tonifying spleen and eliminating dampness, clearing heat and drying dampness, the prescription is mainly used for treating gastral cavity pain, relapse and aggravation of defending against cold and the like, and the prescription has a remarkable curative effect in actual clinical application.

Description

Technical Field

[0001] The present application relates to the technical field of traditional Chinese medicine formulas, and in particular to a traditional Chinese medicine composition for dispelling cold in gastritis and a preparation method thereof. Background Art

[0002] Gastritis is an acute and chronic inflammation of the gastric mucosa caused by a variety of different causes, often accompanied by epithelial damage, mucosal inflammatory response and epithelial regeneration. It is one of the most common digestive system diseases. Symptoms include epigastric discomfort, pain, fullness after meals, belching, acid reflux, and even nausea and vomiting. There are many drugs on the market for the treatment of gastritis, chronic gastritis, superficial gastritis, antral gastritis, gastric polyps, etc., but there is a disadvantage of slow efficacy. According to the clinical onset and duration of the disease, gastritis is generally divided into acute gastritis and chronic gastritis. Acute gastritis is an acute inflammation of the gastric mucosa caused by a variety of causes. Clinically, it is acutely onset, often manifested by symptoms such as upper abdominal discomfort and dull pain.

[0003] At present, there are many kinds of drugs for treating gastritis. Although western medicine has certain effects, it often damages other organs such as liver and kidneys while treating gastritis. Moreover, the efficacy is unstable and it is easy to relapse after recovery. According to the syndrome type, traditional Chinese medicine divides gastritis into liver-stomach disharmony syndrome, spleen-stomach deficiency syndrome, spleen-stomach damp-heat syndrome, stomach yin deficiency syndrome, stomach collateral stasis syndrome, and spleen deficiency and qi stagnation syndrome. The treatment principle of traditional Chinese medicine for liver-stomach disharmony syndrome is to soothe the liver and regulate qi, harmonize the stomach and relieve depression, the treatment principle for spleen-stomach deficiency syndrome is to warm the middle and strengthen the spleen, invigorate qi and harmonize the stomach, the treatment principle for spleen-stomach damp-heat syndrome is to clear away heat and dampness, harmonize the middle and wake up the spleen, the treatment principle for stomach yin deficiency syndrome is to nourish yin and benefit the stomach, harmonize the collaterals and relieve pain, the treatment principle for stomach collateral stasis syndrome is to activate blood circulation and remove blood stasis, promote qi and relieve pain, and the treatment principle for spleen deficiency and qi stagnation syndrome is to invigorate the spleen and regulate qi, activate blood circulation and remove blood stasis. Summary of the invention

[0004] The purpose of the present application is to provide a traditional Chinese medicine composition for dispelling cold in gastritis, which has the effects of strengthening the spleen and eliminating dampness, warming the middle and dispelling cold, and relieving pain.

[0005] Another object of the present application is to provide a method for preparing a traditional Chinese medicine composition for dispelling cold in gastritis, which is simple and convenient.

[0006] The present application solves the technical problem by adopting the following technical solution.

[0007] On the one hand, an embodiment of the present application provides a traditional Chinese medicine composition for dispelling cold in gastritis, which includes the following Chinese medicinal materials: Atractylodes lancea, Atractylodes macrocephala, Magnolia officinalis, Licorice, Patchouli, Coptis chinensis, ginger charcoal, Evodia rutaecarpa, Tangerine peel, White cardamom, Poria cocos, Pinellia ternata, Codonopsis pilosula and Cortex cerasifera.

[0008] On the other hand, the present invention provides a method for preparing a Chinese medicine composition for dispelling cold in gastritis, comprising the following steps:

[0009] S1. Crush dried orange peel, white cardamom, Poria, Pinellia ternata, Codonopsis pilosula and Corrugated seeds to obtain fine powder;

[0010] S2, boiling Atractylodes lancea, Atractylodes macrocephala, Magnolia officinalis, Licorice root, Patchouli, Coptis chinensis, Ginger charcoal and Evodia rutaecarpa with water for several times, combining the decoctions, collecting the supernatant after precipitation and concentrating it into a clear paste;

[0011] S3, mixing the above-mentioned fine powder and clear paste, adding monosaccharide syrup and mixing to form granules, and pressing them into tablets after drying to obtain the traditional Chinese medicine composition for dispelling cold in gastritis.

[0012] The medication mechanism of the present application is: Evodia rutaecarpa is pungent in nature and can warm the stomach and stop vomiting; ginger charcoal warms the stomach and dispels cold, and at the same time can reduce adverse reactions and stop vomiting, to help the power of Evodia rutaecarpa; Codonopsis pilosula, Poria cocos, Atractylodes macrocephala, and Licorice are based on the meaning of the Four Gentlemen to invigorate Qi and strengthen the spleen; Atractylodes macrocephala dries dampness and invigorates the spleen; Pinellia ternata and Tangerine peel are based on the meaning of Erchen Decoction to dry dampness and resolve phlegm, regulate Qi and harmonize the middle; Patchouli is aromatic and can transform the dampness and turbidity inside, and can avoid filth and harmonize the middle, raise the clear and lower the turbid; Magnolia officinalis and White Amomum villosum promote Qi and resolve dampness, clear the middle and eliminate fullness; Coptis chinensis clears heat and dries dampness; Coriander seed eliminates phlegm and resolves blood stasis, and suppresses acid to relieve pain; the whole formula is used together to achieve the effects of warming the stomach and dispelling cold, invigorating the spleen and removing dampness, and clearing heat and drying dampness.

[0013] Compared with the prior art, the embodiments of the present application have at least the following advantages or beneficial effects:

[0014] The present application combines the common spleen-strengthening and qi-regulating, heat-clearing and dampness-removing treatment mechanism of gastritis with the method of dispelling cold to form a new prescription for treating gastritis. The prescription adopts 14 herbs including Atractylodes macrocephala, Atractylodes macrocephala, Magnolia officinalis, Licorice, Patchouli, Coptis chinensis, ginger charcoal, Evodia rutaecarpa, Tangerine peel, White cardamom, Poria, Pinellia ternata, Codonopsis pilosula and Corrugated caraway as the prescription, which has the effects of warming the stomach and dispelling cold, strengthening the spleen and removing dampness, clearing away heat and drying dampness, and is mainly used to treat epigastric pain, relapse and aggravation of cold, etc., and has significant therapeutic effects in actual clinical application. DETAILED DESCRIPTION

[0015] In order to make the purpose, technical scheme and advantages of the embodiments of the present application clearer, the technical scheme in the embodiments of the present application will be described clearly and completely below. If the specific conditions are not specified in the embodiments, they are carried out according to the conventional conditions or the conditions recommended by the manufacturer. If the manufacturer is not specified for the reagents or instruments used, they are all conventional products that can be purchased commercially.

[0016] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present application will be described in detail below with reference to specific embodiments.

[0017] A traditional Chinese medicine composition for dispelling cold in gastritis comprises the following Chinese medicinal materials: atractylodes, white atractylodes, magnolia bark, liquorice, patchouli, coptis root, ginger charcoal, evodia rutaecarpa, tangerine peel, cardamom, tuckahoe, pinellia, codonopsis and corrugated paper.

[0018] In some embodiments of the present application, the above-mentioned Chinese medicine composition includes the following Chinese medicinal materials, by weight: 30-50 parts of Atractylodes lancea, 30-50 parts of Atractylodes macrocephala, 30-50 parts of Magnolia officinalis, 20-28 parts of Licorice, 45-55 parts of Patchouli, 12-20 parts of Coptis chinensis, 30-50 parts of ginger charcoal, 28-35 parts of Evodia rutaecarpa, 50-65 parts of Citrus reticulata, 22-30 parts of Amomum villosum, 100-140 parts of Poria, 30-50 parts of Pinellia ternata, 50-70 parts of Codonopsis pilosula and 65-80 parts of Cortex Alpiniae.

[0019] In some embodiments of the present application, the above-mentioned Chinese medicine composition includes the following Chinese medicinal materials, measured by weight: 40 parts of Atractylodes lancea, 40 parts of Atractylodes macrocephala, 40 parts of Magnolia officinalis, 24 parts of Licorice, 48 parts of Patchouli, 16 parts of Coptis chinensis, 40 parts of ginger charcoal, 32 parts of Evodia rutaecarpa, 60 parts of Citrus reticulata, 28 parts of Amomum villosum, 120 parts of Poria, 40 parts of Pinellia ternata, 60 parts of Codonopsis pilosula and 72 parts of Cortex Alpiniae.

[0020] In some embodiments of the present application, the Atractylodes lancea is stir-fried with bran, the Atractylodes macrocephala is stir-fried with bran, the Magnolia officinalis is stir-fried with ginger juice, the Evodia rutaecarpa is Glycyrrhiza uralensis stir-fried with water, and the Corrugated Carrageenan is calcined Corrugated Carrageenan.

[0021] A method for preparing a Chinese medicine composition for dispelling cold in gastritis comprises the following steps:

[0022] S1. Crush dried orange peel, white cardamom, Poria, Pinellia ternata, Codonopsis pilosula and Corrugated seeds to obtain fine powder;

[0023] S2, boiling Atractylodes lancea, Atractylodes macrocephala, Magnolia officinalis, Licorice root, Patchouli, Coptis chinensis, Ginger charcoal and Evodia rutaecarpa with water for several times, combining the decoctions, collecting the supernatant after precipitation and concentrating it into a clear paste;

[0024] S3, mixing the above-mentioned fine powder and clear paste, adding monosaccharide syrup and mixing to form granules, and pressing them into tablets after drying to obtain the traditional Chinese medicine composition for dispelling cold in gastritis.

[0025] In some embodiments of the present application, the fine powder in the above step S1 is sieved through an 80-100 mesh sieve.

[0026] In some embodiments of the present application, the decoction is performed twice in step S2, the first decoction is 1.5-2.5 h, and the second decoction is 0.5-1.5 h. The amount of water added in the two times is 10 times and 6 times the weight of the Chinese medicinal materials, respectively.

[0027] In some embodiments of the present application, the relative density of the clear paste is 1.21-1.26.

[0028] In some embodiments of the present application, the amount of simple syrup added is 5-10% of the total mass of the clear paste and the fine powder.

[0029] The features and performance of the present application are further described in detail below in conjunction with the embodiments.

[0030] Example 1

[0031] A Chinese medicine composition for dispelling cold in gastritis, which is prepared by the following method:

[0032] Weigh the raw materials: 40g of Atractylodes (fried with bran), 40g of Atractylodes (fried with bran), 40g of Houbu (fried with ginger juice), 24g of Licorice, 48g of Patchouli, 16g of Coptis chinensis, 40g of Ginger Charcoal, 32g of Evodia (fried with licorice water), 60g of Tangerine Peel, 28g of White Cardamom, 120g of Poria, 40g of Pinellia, 60g of Codonopsis and 72g of Corrugated Seed (calcined);

[0033] Tangerine peel, white cardamom, Poria, French pinellia, Codonopsis pilosula and corrugated fruit are crushed into fine powder and passed through 100 mesh. The remaining atractylodes, white atractylodes, Magnolia bark, liquorice, Patchouli, Coptis chinensis, ginger charcoal and Evodia rutaecarpa are decocted twice with water, the first time for 2 hours and the second time for 1 hour. The amount of water added twice is 10 times and 6 times the weight of the Chinese medicinal materials, respectively. The two decoctions are combined and precipitated overnight. The supernatant is concentrated to a clear paste with a relative density of 1.25, mixed with the above-mentioned fine powder, and an appropriate amount of monosaccharide syrup (8% of the total mass of the clear paste and fine powder) is added. The mixture is mixed into granules, dried, and pressed into 1000 tablets to obtain the Chinese medicine tablet composition of the present embodiment.

[0034] Example 2

[0035] A Chinese medicine composition for dispelling cold in gastritis, which is prepared by the following method:

[0036] Weigh the raw materials: 45g of Atractylodes (fried with bran), 38g of Atractylodes (fried with bran), 40g of Houbu (fried with ginger juice), 25g of Licorice, 50g of Patchouli, 16g of Coptis chinensis, 42g of ginger charcoal, 32g of Evodia (fried with licorice water), 65g of Tangerine Peel, 30g of White Cardamom, 125g of Poria, 38g of Pinellia, 60g of Codonopsis pilosula and 70g of Corrugated Carrot (calcined);

[0037] Tangerine peel, white cardamom, Poria, French pinellia, Codonopsis pilosula and corrugated fruit are crushed into fine powder and passed through 300 mesh. The remaining atractylodes, white atractylodes, Magnolia bark, liquorice, Patchouli, Coptis chinensis, ginger charcoal and Evodia rutaecarpa are decocted twice with water, the first time for 2 hours and the second time for 1 hour. The amount of water added twice is 10 times and 6 times the weight of the Chinese medicinal materials, respectively. The two decoctions are combined and precipitated overnight. The supernatant is concentrated to a clear paste with a relative density of 1.24, mixed with the above-mentioned fine powder, and an appropriate amount of monosaccharide syrup (5% of the total mass of the clear paste and fine powder) is added. The mixture is mixed into granules, dried, and pressed into 1000 tablets to obtain the Chinese medicine tablet composition of the present embodiment.

[0038] Example 3

[0039] A Chinese medicine composition for dispelling cold in gastritis, which is prepared by the following method:

[0040] Weigh the raw materials: 38g of Atractylodes (fried with bran), 40g of Atractylodes (fried with bran), 40g of Houbu (fried with ginger juice), 22g of Licorice, 52g of Patchouli, 12g of Coptis chinensis, 48g of ginger charcoal, 35g of Evodia (fried with licorice water), 60g of Tangerine Peel, 30g of White Cardamom, 130g of Poria, 30g of Pinellia, 66g of Codonopsis and 72g of Corrugated Seed (calcined);

[0041] Tangerine peel, white cardamom, Poria, French pinellia, Codonopsis pilosula and corrugated fruit are crushed into fine powder and passed through 300 mesh. The remaining atractylodes, white atractylodes, Magnolia bark, liquorice, Patchouli, Coptis chinensis, ginger charcoal and Evodia rutaecarpa are decocted twice with water, the first time for 2.5 hours and the second time for 1 hour. The amount of water added twice is 10 times and 6 times the weight of the Chinese medicinal materials, respectively. The two decoctions are combined and precipitated overnight. The supernatant is concentrated to a clear paste with a relative density of 1.22, mixed with the above-mentioned fine powder, and an appropriate amount of monosaccharide syrup (10% of the total mass of the clear paste and fine powder) is added. The mixture is mixed into granules, dried, and pressed into 1000 tablets to obtain the Chinese medicine tablet composition of the present embodiment.

[0042] Example 4

[0043] A Chinese medicine composition for dispelling cold in gastritis, which is prepared by the following method:

[0044] Weigh the raw materials: 36g of Atractylodes (fried with bran), 46g of Atractylodes (fried with bran), 35g of Houbu (fried with ginger juice), 28g of Licorice, 45g of Patchouli, 20g of Coptis chinensis, 45g of Ginger Charcoal, 35g of Evodia (fried with licorice water), 65g of Tangerine Peel, 22g of White Cardamom, 100g of Poria, 34g of Pinellia, 70g of Codonopsis and 75g of Corrugated Seed (calcined);

[0045] Tangerine peel, white cardamom, Poria, French pinellia, Codonopsis pilosula and corrugated fruit are crushed into fine powder and passed through 300 mesh. The remaining atractylodes, white atractylodes, Magnolia bark, liquorice, Patchouli, Coptis chinensis, ginger charcoal and Evodia rutaecarpa are decocted twice with water, the first time for 2.5 hours and the second time for 1.5 hours. The amount of water added twice is 10 times and 6 times the weight of the Chinese medicinal materials, respectively. The two decoctions are combined and precipitated overnight. The supernatant is concentrated to a clear paste with a relative density of 1.22, mixed with the above-mentioned fine powder, and an appropriate amount of monosaccharide syrup (6% of the total mass of the clear paste and fine powder) is added. The mixture is mixed into granules, dried, and pressed into 1000 tablets to obtain the Chinese medicine tablet composition of the present embodiment.

[0046] Example 5

[0047] A Chinese medicine composition for dispelling cold in gastritis, which is prepared by the following method:

[0048] Weigh the raw materials: 40g of Atractylodes (fried with bran), 30g of Atractylodes (fried with bran), 50g of Houbu (fried with ginger juice), 26g of Licorice, 53g of Patchouli, 22g of Coptis chinensis, 50g of Ginger Charcoal, 28g of Evodia (fried with licorice water), 63g of Tangerine Peel, 28g of White Cardamom, 110g of Poria, 30g of Pinellia, 60g of Codonopsis and 80g of Corrugated Carrot (calcined);

[0049] Tangerine peel, white cardamom, Poria, French pinellia, Codonopsis pilosula and corrugated fruit are crushed into fine powder and passed through 100 mesh. The remaining Atractylodes, Atractylodes, Magnolia officinalis, Licorice, Patchouli, Coptis chinensis, ginger charcoal and Evodia rutaecarpa are decocted twice with water, the first time for 2 hours and the second time for 0.5 hour. The amount of water added twice is 10 times and 6 times the weight of the Chinese medicinal materials, respectively. The two decoctions are combined and precipitated overnight. The supernatant is concentrated to a clear paste with a relative density of 1.22, mixed with the above-mentioned fine powder, and an appropriate amount of monosaccharide syrup (6% of the total mass of the clear paste and fine powder) is added. The mixture is mixed into granules, dried, and pressed into 1000 tablets to obtain the Chinese medicine tablet composition of the present embodiment.

[0050] Example 6

[0051] A Chinese medicine composition for dispelling cold in gastritis, which is prepared by the following method:

[0052] Weigh the raw materials: 45g of Atractylodes (fried with bran), 30g of Atractylodes (fried with bran), 32g of Houbu (fried with ginger juice), 22g of Licorice, 50g of Patchouli, 22g of Coptis chinensis, 50g of Ginger Charcoal, 30g of Evodia (fried with licorice water), 60g of Tangerine Peel, 25g of White Cardamom, 110g of Poria, 30g of Pinellia, 65g of Codonopsis pilosula and 65g of Corrugated Carrot (calcined);

[0053] Tangerine peel, white cardamom, Poria, French pinellia, Codonopsis pilosula and corrugated fruit are crushed into fine powder and passed through 100 mesh. The remaining atractylodes, white atractylodes, Magnolia bark, liquorice, Patchouli, Coptis chinensis, ginger charcoal and Evodia rutaecarpa are decocted twice with water, the first time for 2 hours and the second time for 0.5 hour. The amount of water added twice is 10 times and 6 times the weight of the Chinese medicinal materials, respectively. The two decoctions are combined and precipitated overnight. The supernatant is concentrated to a clear paste with a relative density of 1.25, mixed with the above-mentioned fine powder, and an appropriate amount of monosaccharide syrup (6% of the total mass of the clear paste and fine powder) is added. The mixture is mixed into granules, dried, and pressed into 1000 tablets to obtain the Chinese medicine tablet composition of the present embodiment.

[0054] Experimental example

[0055] The Chinese medicine tablet composition prepared in Example 1 above was tested;

[0056] Properties: This product is gray-brown tablets; tastes sweet, slightly spicy and bitter.

[0057] Identification: (1) Take this product and observe it under a microscope. The off-white pieces vary in size, and the surface is mostly uneven and granular, and some have fine textures. Calcium oxalate crystals are present in flakes in the thin-walled cells of the pericarp. Stone cells are scattered singly or in groups, and are polygonal, rhombic, or short spindle-shaped. Most of them have a pointed protrusion, sparse pits, and obvious grooves. The goblet cells in the endocarp are in flakes, yellow-brown, polygonal in surface, thick in wall, and contain siliceous blocks in the cell cavity. Calcium oxalate needle crystals are present in mucus cells. Irregular branched masses are colorless and easily melted in chloral hydrate solution. Mycelium is colorless or light brown.

[0058] (2) Take 5 tablets of this product, grind them, add 20 ml of ether, and perform ultrasonic extraction for 10 minutes. Let it stand, take 5 ml of the supernatant, put it in a white porcelain evaporating dish, evaporate the ether, and add 1-2 drops of 1% vanillin sulfuric acid solution to the residue, which will turn purple and gradually turn purple-red after standing.

[0059] (3) Take the residue after ether extraction in identification (2), evaporate the ether, add 15 ml of water, perform ultrasonic extraction for 15 minutes, filter, take the filtrate, add a small amount of activated carbon for warm immersion decolorization, filter, take 1 ml of the filtrate, add 2 drops of methyl red indicator solution, add 2 drops of ammonium oxalate test solution, and a white precipitate will be generated. Separate it. The precipitate is insoluble in acetic acid but soluble in hydrochloric acid.

[0060] (4) Take 10 tablets of this product, grind them, add 20ml of ethanol, seal, shake for 30 minutes, filter, and concentrate the filtrate to about 1ml as the test solution. Take 0.1g of powder of the reference medicinal material of Coptis chinensis and prepare the reference medicinal material solution in the same way. Then remove the berberine hydrochloride reference substance and add ethanol to prepare a solution containing 0.5mg per 1ml as the reference solution. According to the thin layer chromatography method (Appendix 0502 of Part IV of the 2020 edition of the Chinese Pharmacopoeia), 10ul of the opera test solution, 5ul of the reference medicinal material solution and the reference substance solution are respectively spotted on the same silica gel G thin layer plate, and ethanol-glacial acetic acid and water (7:2:1) are used as the developing agent. Develop, take out, dry, and examine under ultraviolet light (365nm). In the chromatogram of the test sample, fluorescent spots of the same color appear at the corresponding positions of the reference medicinal material and the reference flat chromatogram.

[0061] Inspection: It should comply with the relevant provisions under tablets (Appendix 0101, Part IV of the Chinese Pharmacopoeia 2020 Edition).

[0062] Usage and Dosage: Oral. 4-6 tablets at a time, 3 times a day.

[0063] Specification: 0.4g×100 tablets.

[0064] Storage: Sealed and stored in a cool place.

[0065] The product prepared in the embodiment of the present application has been gradually used clinically, and has the effects of strengthening the spleen and eliminating dampness, warming the middle and dispelling cold, and relieving pain. It is mainly used to treat epigastric pain, cold-resistant recurrence and aggravation, etc., and the effect is obvious.

[0066] Typical cases:

[0067] 1. Mr. Li, male, 43 years old, had long-term abdominal distension, belching, and epigastric pain. The pain was accompanied by a cold feeling in the epigastric area, which was relieved by warmth. He had been treated in other hospitals and taken semitoprazole but was not cured. He was treated with the prepared Chinese medicine granules, 4 to 6 tablets three times a day, morning and evening, for two weeks, and his condition improved significantly.

[0068] 2. Qian, female, 40 years old, often felt dry and bitter mouth, bland taste and preferred hot drinks, loose stools, pale tongue with thin white coating, slow pulse, and occasional acid reflux. She had taken omeprazole but did not see improvement. She was treated with the prepared Chinese medicine granules, 4 to 6 tablets three times a day, morning and evening, for four weeks, and then the symptoms disappeared.

[0069] In summary, the Chinese medicine composition for dispelling cold in gastritis and the preparation method thereof in the embodiments of the present application have the following advantages: the present application combines the dispelling cold method with the common mechanism of treating gastritis of strengthening the spleen and regulating qi, clearing away heat and removing dampness, to form a new prescription for treating gastritis. The prescription adopts 14 herbs including Atractylodes lancea, Atractylodes macrocephala, Magnolia officinalis, Licorice, Patchouli, Coptis chinensis, Ginger charcoal, Evodia rutaecarpa, Tangerine peel, White cardamom, Poria, Pinellia ternata, Codonopsis pilosula and Corrugated caraway as the prescription, which has the effects of warming the stomach and dispelling cold, strengthening the spleen and removing dampness, clearing away heat and drying dampness, and is mainly used to treat epigastric pain, relapse and aggravation of cold, etc., and has significant therapeutic effect in actual clinical application.

[0070] The embodiments described above are part of the embodiments of the present application, rather than all of the embodiments. The detailed description of the embodiments of the present application is not intended to limit the scope of the present application for protection, but merely represents the selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present application.

Claims

1. A Chinese medicine composition for dispelling cold in gastritis, characterized in that: It includes the following Chinese medicinal materials: Atractylodes lancea, Atractylodes macrocephala, Magnolia officinalis, Licorice, Patchouli, Coptis chinensis, Ginger charcoal, Evodia rutaecarpa, Tangerine peel, White cardamom, Poria cocos, Pinellia ternata, Codonopsis pilosula and Corrugated caraway seeds.

2. A Chinese medicine composition for dispelling cold in gastritis according to claim 1, characterized in that: Calculated by weight, the invention comprises the following Chinese medicinal materials: 30-50 parts of Atractylodes lancea, 30-50 parts of Atractylodes macrocephala, 30-50 parts of Magnolia officinalis, 20-28 parts of Licorice, 45-55 parts of Patchouli, 12-20 parts of Coptis chinensis, 30-50 parts of ginger charcoal, 28-35 parts of Evodia rutaecarpa, 50-65 parts of Citrus reticulata, 22-30 parts of Amomum villosum, 100-140 parts of Poria, 30-50 parts of Pinellia ternata, 50-70 parts of Codonopsis pilosula and 65-80 parts of Cortex citrus.

3. A Chinese medicine composition for dispelling cold in gastritis according to claim 2, characterized in that: Calculated by weight, the following Chinese medicinal materials are included: 40 parts of Atractylodes lancea, 40 parts of Atractylodes macrocephala, 40 parts of Magnolia officinalis, 24 parts of Licorice, 48 parts of Patchouli, 16 parts of Coptis chinensis, 40 parts of ginger charcoal, 32 parts of Evodia rutaecarpa, 60 parts of Citrus reticulata, 28 parts of Amomum villosum, 120 parts of Poria, 40 parts of Pinellia ternata, 60 parts of Codonopsis pilosula and 72 parts of Cortex Aconiti Lateralis.

4. A Chinese medicine composition for dispelling cold in gastritis according to any one of claims 1 to 3, characterized in that: The Atractylodes is stir-fried with bran, the Atractylodes is stir-fried with bran, the Magnolia officinalis is stir-fried with ginger juice, the Evodia rutaecarpa is stir-fried with water and the Corrugated Carrageenan is calcined Corrugated Carrageenan.

5. A method for preparing a Chinese medicine composition for dispelling cold in gastritis as claimed in any one of claims 1 to 4, characterized in that: The following steps are involved: S1. Crush dried orange peel, white cardamom, Poria, Pinellia ternata, Codonopsis pilosula and Corrugated seeds to obtain fine powder; S2, boiling Atractylodes lancea, Atractylodes macrocephala, Magnolia officinalis, Licorice root, Patchouli, Coptis chinensis, Ginger charcoal and Evodia rutaecarpa with water for several times, combining the decoctions, collecting the supernatant after precipitation and concentrating it into a clear paste; S3, mixing the above-mentioned fine powder and clear paste, adding monosaccharide syrup and mixing to form granules, and pressing them into tablets after drying to obtain the traditional Chinese medicine composition for dispelling cold in gastritis.

6. The method for preparing a Chinese medicine composition for dispelling cold in gastritis according to claim 5, characterized in that: The fine powder in step S1 is sieved through a 80-100 mesh sieve.

7. The method for preparing a Chinese medicine composition for dispelling cold in gastritis according to claim 5, characterized in that: The decoction is performed twice in step S2, the first decoction is 1.5-2.5 hours, and the second decoction is 0.5-1.5 hours. The amount of water added in the two times is 10 times and 6 times the weight of the Chinese medicinal materials, respectively.

8. The method for preparing a Chinese medicine composition for dispelling cold in gastritis according to claim 5, characterized in that: The relative density of the clear paste is 1.21-1.

26.

9. The method for preparing a Chinese medicine composition for dispelling cold in gastritis according to claim 5, characterized in that: The added amount of the monosaccharide syrup is 5-10% of the total mass of the clear paste and the fine powder.