298results about How to "Suitable for long term storage" patented technology

The invention relates to the field of stem cells, discloses a method for preparing exosome freeze-dried powder of stem cells, and particularly relates to a method for preparing exosome freeze-dried powder of human amniotic mesenchymal stem cells. The method for preparing the exosome freeze-dried powder of the human amniotic mesenchymal stem cells disclosed by the invention comprises the following steps: mixing trehalose with exosomes of the human amniotic mesenchymal stem cells as a cryoprotectant; filtering and removing bacteria by virtue of a filter membrane; and firstly carrying out ultralow temperature pre-freezing, and then carrying out low-temperature freezing at a certain vacuum degree. The preparation method disclosed by the invention is simple to operate, safe and effective. An experiment proves that compared with a conventional preparation method of the freeze-dried powder, the morphologies and the activity of the exosomes of the human amniotic mesenchymal stem cells can be well kept by the method for preparing the exosome freeze-dried powder of the human amniotic mesenchymal stem cells disclosed by the invention; and the method is suitable for long-term preservation and application of the exosomes of the human amniotic mesenchymal stem cells.

The invention discloses a moxa cone coiling forming machine which comprises a spiral conveying mechanism, a paper tape winding mechanism, a gluing and forming mechanism and a shearing mechanism which are arranged in sequence, wherein the spiral conveying mechanism is used for forming a naked moxa cone; the paper tape winding mechanism mainly consists of a paper coiling disc and a paper tape; a conical guide groove of which the front part is large and the rear part is small is formed in the paper coiling disc; the width of the paper tape is greater than the perimeter of the naked moxa cone; the paper tape is paved inside the conical guide groove in the paper coiling disc in a dynamic conveying manner; the gluing and forming mechanism mainly consists of a gluing machine and a sealing ring; the gluing machine is used for gluing the paper tape; the sealing ring is used for shifting, guiding and compacting the glued paper tape when the paper tape is dynamically conveyed, so as to coil and seal the paper tape; the shearing mechanism is used for shearing the coiled and formed moxa cone output from the gluing and forming mechanism. The moxa cone coiling forming machine is capable of automatically and continuously producing coiled paper moxa cones and is applicable to large-scale in-batch production, the whole production process is clean, sanitary, free of pollution, high in production efficiency and low in cost, and the formed moxa cones are high in medicinal quality.

The invention discloses an abiraterone acetate polymorphic substance I, and a preparation method and pharmaceutical composition thereof.

The invention discloses a dasatinib polymorphic substance. In addition, the invention also discloses a preparation method and a medicinal composition of the dasatinib polymorphic substance. The dasatinib polymorphic substance provided by the invention has the advantages of good physicochemical property and good stability, is more suitable for industrial scale preparation, and the like.

The invention discloses a preparation method of composite gel micro-spheres. The preparation method comprises the following steps: performing modification treatment on silk fibroins to obtain a methacrylate anhydride silk fibroin solution; adding a methacrylate anhydride bio-polymerized molecular solution and a photo-initiator to obtain a pre-polymer solution; preparing composite micro-droplets bythe pre-polymer solution, performing radiation treatment with blue light to obtain the silk fibroin protein and the bio-polymerized molecule composite gel microspheres. The composite gel microsphereswith high mechanical property and good biocompatibility can be prepared by the method. The invention further discloses a cell coating method based on the preparation method; composite gel microsphere-coated cells are small in damage and low in toxicity and can be obtained with good survival and proliferation. The invention also discloses the composite gel micro-spheres prepared by the method andapplication thereof to cell 3D culture, 3D printing and use as biomedical materials; the composite gel micro-spheres have a wide application to the biomedical field through good biocompatibility and mechanical property.

The invention discloses a method for preparing wax emulsion from branched polyethylene wax through direct emulsification, which comprises the following steps of: mixing the branched polyethylene wax and a cosolvent, adding an emulsifier and heating and emulsifying; adding water and dispersing and emulsifying by a phase transfer method; and shearing, emulsifying and dispersing to prepare milky branched polyethylene wax emulsion. In the emulsification method, the cosolvent is added into the branched polyethylene wax for direct emulsifying, and the process for production of the emulsion is greatly simplified. The branched polyethylene wax emulsion can be applied in the fields of leather finish, fur finishing, textile finishing, automobile polishing, shoe cream and the like, the coating has smooth handfeel, natural color, high hardness and high scratch resistance, and the wax emulsion is a high-grade wax emulsion product. The emulsification process can greatly expand the use of the branched polyethylene wax and reduce the application of solvent products, and is an environmentally-friendly emulsification process.

The invention relates to a method for preparing a functional type food containing persimmon. The technical scheme provided by the invention is as follows: the method comprises the following steps of: carrying out re-acerbity resistant treatment on persimmons: softening mature persimmons, cleaning, removing bases, pulping, and embedding by adding a compound debitterizing agent containing 2-5% of beta-cyclodextrin and maltodextrin to prevent re-acerbity; adding the prepared substances into ingredients; and deeply processing: stirring, mixing, rubber grinding, refining, slicing, drying, uncovering slices, overlapping slices, and slicing, wherein the embedding time is 50-70 min; and the embedding temperature is 35-45 DEG C. By adopting the technical scheme, the method disclosed by the invention has the benefits that: persimmons are processed into serial fruit paste type leisure foods which have the advantages of being good in mouth feel, easy for storage and applicable to being eaten by men and women of all ages; a condition is created for persimmon industrialization; unlike other foods containing persimmons, the produced foods can avoid re-acerbity phenomenon, taste good and tenacious and are suitable for being stored for a long time; and the technical problem which is expected to solve for a long time but not solved is solved.

The invention discloses a crystal IV of 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindole-2-yl) piperidine-2,6-diketone. 2theta expressed by degrees has diffraction peaks between 7.7+ / -0.2 and 11.9+ / -0.2 in the X-ray diffraction pattern of the crystal. Moreover, the invention also discloses a preparation method and a medicinal composite of the crystal.

The invention relates to an anhydrous peramivir crystal compound and a preparation method thereof, and further discloses a pharmaceutical composition comprising the same and the application thereof in the preparation of medicaments for treating the influenza virus and the Avian influenza virus.

The invention discloses a moisturizing composition with an anti-allergy repairing efficacy and preparation and application to skincare products. The composition is prepared from xanthan gum, pullulan,polyglutamic acid, hyaluronic acid, trehalose, allantoin, urea and chondroitin sulfate by reasonable compounding. The composition has a function of stereo moisturizing of all skin layers including acorium layer, an epidermal layer, a cuticle layer and a skin surface, the skin moisture content can be increased, and skin moisture loss is reduced. The composition is capable of inhibiting hyaluronidase activity, soothing skin allergy and pruritus and repairing skin barrier. The composition has excellent moisturizing effects and an anti-allergy repairing efficacy in vitro and on human skin, effects are remarkably improved as compared with those of single use of each component, and accordingly synergistic effects are achieved by combination of the components in an appropriate ratio. The composition is solid powder and free of any preservatives, and convenience in long-time storage and transport is achieved. The composition can be applied to all types of skincare and cleansing products.

The invention provides a biological sporoderm-breaking technology and an effective antioxidation method for ganoderma lucidum spore powder. Firstly, full mature ganoderma lucidum spores are screened and put into water to be cleaned, then the ganoderma lucidum spores are heated after being frozen, spore enzymolysis and sporoderm breaking are carried out with one of expansin, cellulose, lysozyme, helicase and the like or the mixture of a plurality of enzymes for 3-24 hours at the temperature of 37-45 DEG C, pH (Potential Of Hydrogen) is regulated to 5.5-6.8 by citric acid, and then a vitamin C is used as an antioxidant of the ganoderma lucidum spore powder. Finally, 1% of sweetener-stevioside is used for removing bitter, and treatment with an instantaneous ultra-high temperature sterilization machine and bagging are carried out. The method disclosed by the invention has a good sterilization effect and high sporoderm breaking efficiency, is low in cost, does not break protoplasm of the ganoderma lucidum spore powder and keeps the original characteristics of the ganoderma lucidum powder.

The invention discloses an adsorption film mixing three metallic oxides and a preparation method thereof and a method for measuring fluorinion based on a gradient diffusion thin film technology. The adsorption film takes three oxides, namely iron, aluminum and cerium as adsorption materials, and the three oxides are uniformly dispersed into a polyacrylamide solution to form a gel and the gel is heated to form an adsorption film. The adsorption film, a diffusion film and a filter membrane are overlapped to assemble a DGT device, and the DGT device is placed into water body and sediments to realize in situ testing of fluorinion and the subcentimetre high resolution detection of fluorinion distributed in the water body and sediments. The adsorption film prepared by adopting the preparation method disclosed by the invention is large in adsorption capacity, long in retention time and easily available in materials; compared with the traditional fluorinion selective electrode method, the fluorinion in situ test method based on the gradient diffusion thin film technology is wide in application range and the result has more representativeness.

The invention relates to a preparation method of fluorocarbon compound liposome. The method comprises the following steps of a. dissolving 1-50 parts by weight of phospholipid and 0-50 parts by weight of cholesterol in 200 parts by weight of an organic solvent, and mixing uniformly under the assistance of ultrasonic; b. adding 10-50 parts by weight of fluorocarbon in the organic solvent with the phospholipid dissolved therein, and continuously mixing uniformly under the assistance of the ultrasonic; and c. dropwise-adding the solution obtained from the step b in 100-500 parts by weight of a salt solution, stirring the solution with a stirring rate of 500-2,500 revolutions per minute until the organic solvent is volatilized completely, the stirring time being 2 hours, and thus the fluorocarbon compound liposome is obtained. The prepared fluorocarbon compound liposome has good stability and small particle size. The method is simple, and is convenient for large-scale production. The prepared fluorocarbon compound liposome can have good applications in the aspects such as emergency oxygen supply drugs, acute blood supply, contrast agents, etc.

The invention relates to a method and a system for realizing storage and query of a communication detailed ticket. The method comprises the following steps: I, performing real-time processing on a real-time generated standard ticket file in a same day detailed ticket storage module to generate a same day detailed ticket storage file according to the number segment; II, performing regulation processing on the same day detailed ticket storage file generated in the former day in a former day detailed ticket regulation module to generate a former day detailed ticket regulation file and establish a day index file; III, compressing and filing all former day detailed ticket regulation files of all users in a designated month in a former month detailer ticket filing module to generate a former month detailed ticket filing file and establish a month index file; and IV, positioning corresponding detailed ticket files according to cell phone numbers and time to complete queries. The system and the method, provided by the invention, adopt different data organization forms for different detailed tickets and perform storage and queries in different ways, so as to reduce the cost and risk, and improve the efficiencies for storage and query of mass data.

The invention discloses a convenient five cereal battercake taking a plurality of cereals as raw materials and a processing method thereof. The convenient five cereal battercake takes wheat flour, green bean powder and soybean meal as main raw materials so as to obtain the convenient five cereal battercake which can be saved for a long time and unpacked when being to be eaten, has good nutrition and taste compared with the prior battercake no matter being soaked, boiled or directly eaten and is suitable for being used as a convenient food for battercake liking crowds through steps, i.e. material mix, spread, frying, and the like.

The invention relates to PLGA ultrasonic nano bubbles integrating ultrasonic imaging, drug delivery and gene therapy into a whole and a preparation method thereof. The preparation method comprises the following steps: preparing drug-loading nano bubbles loaded with a chemotherapy drug DOX, further modifying PLGA nano bubbles through PEI, adsorbing shRNA plasmids of MDR-1, thereby forming the composite nano bubbles. The nano bubbles have high drug loading rate and encapsulation efficiency, drug release has pH responsiveness, the loaded genes can be protected, expression of drug resistance genes MDR-1 is effectively silenced, the ultrasonic imaging capacity can be exerted, and the drugs and genes can be simultaneously and efficiently delivered to tumor locations to exert a synergistic effect.

The invention discloses zirconium-based metal organic frameworks UiO-66 and application thereof, and further discloses a preparation method. The preparation method comprises the steps that zirconium tetrachloride and acetic acid are dissolved in N, N-dimethylformamide, terephthalic acid is added, and uniform stirring is carried out so as to obtain a mixed reaction solution; and the mixed reactionsolution is transferred into a reaction kettle and is placed at the temperature of 120 DEG C for reaction for 7-24 hours, then cooling is carried out to reach room temperature, solid-liquid separationis carried out, and then solid obtained after solid-liquid separation is cleaned and dried so as to obtain the zirconium-based metal organic frameworks UiO-66. The zirconium-based metal organic frameworks UiO-66 can serve as a liquid binding phase of a DGT(diffusive gradients in thin-films) device and are used for measuring the active phosphorus of a water body; and the zirconium-based metal organic frameworks UiO-66 have good binding capacity for the phosphorus and can be applied to the DGT(diffusive gradients in thin-films) device as the liquid binding phase, so that in-situ collection andrapid detection can be carried out on the active phosphorus of the water body, in addition, the operation is simple, the accuracy is high, the stability is good, and the the zirconium-based metal organic frameworks UiO-66 are suitable for long-term storage and large-scale production.

The invention provides an underground semiconductor refrigerating device which comprises a base pipe, a lower connector, a heat-insulating box, a heat-conducting block, a semiconductor refrigerating sheet, a radiating block, a heat-insulating box cover and an upper connector, wherein the lower connector and the upper connector are respectively sleeved on the base pipe from the lower end and upper end of the base pipe; extending parts of the lower connector and the upper connector are lap-jointed; the heat-insulating box is sleeved between the base pipe and the lower connector or the upper connector; a heat-conducting through hole matched with the heat-conducting block is arranged on an outer wall of the heat-insulating box; the heat-conducting block, the semiconductor refrigerating sheet and the radiating block are embedded into the heat-conducting through hole in turn from outer to inner; and the semiconductor refrigerating sheet is used for forming a refrigerating surface on an inner surface and a radiating surface on an outer surface under a working state. According to the underground semiconductor refrigerating device, a temperature difference of the inner and outer surfaces is formed on the semiconductor refrigerating sheet and a heat conducting flow from inner to outer is formed at the heat-conducting through hole by the heat-insulating box, so that the real-time control on the required temperature in the heat-insulating box is realized.

A beverage bottle capable of generating healthy water comprises a bottle body and a bottle cap; and a healthy water generator is fixed below the cap bottom of the bottle cap and / or above the bottle bottom of the bottle body and comprises a shell and hydrogen composite ceramic water purifying particles in the shell. A hydrogen composite ceramic water purifying material is a pure natural hydrogen-rich material, tourmaline, medical stone, lapilli and other thirteen kinds of ore are smashed into an ultramicro powder material, then various kinds of rare earth metal materials, photocatalytic enzymes and other elements are blended in the ultramicro powder material, mixing and forming are performed, and finally, the particles in different sizes and different shapes are prepared through baking and low-temperature firing. Firstly, the particles are placed in the beverage bottle, then the beverage bottle is filled with potable water in the market, the potable water can react with the above hydrogen composite ceramic water purifying material to generate hydrogen-rich small molecular group water, and meanwhile, negative electric potential water and weak alkalinity water are made, namely so-called healthy water.

The invention relates to a paper pulp mould product which is antimicrobial and rotproof, protects the environment and can be used for a long time. The technical point is to prepare the paper pulp mould product by using the paper pulp made of Chinese stellera roots. The paper pulp mould product has the advantages that the fiber flexibility is good, the product is not crisp, the product is antimicrobial and rotproof as well as mothproof and acid and alkali resistant, etc., is suitable for a long-time storage, has the natural straw yellow green color and is particularly suitable for storing valuables and valuable medical materials for a long time.

The invention discloses cocktail method bi-color freeze-dried powder, and further discloses a preparation method of the cocktail method bi-color freeze-dried powder. The cocktail method bi-color freeze-dried powder comprises an upper-layer freeze-dried powder body and a lower-layer freeze-dried powder body; and the upper-layer freeze-dried powder body includes oligopeptide-1, oligopeptide-3 and anexcipient A, and the lower-layer freeze-dried powder body includes tripeptide-1 copper, carnosine and an excipient B, wherein the specific weight of the excipient A is smaller than that of the excipient B. According to the cocktail method bi-color freeze-dried powder, different functional additive components are suitable for being stored in different systems, thus every two systems can be added with more functional additives, the different systems are not prone to acting mutually before the functional additives are freeze-dried, more stability is achieved after freeze-drying, and thus the freeze-dried powder is suitable for being stored for a long term; and during using, the systems are redissolved into one system through a solvent, according to molecular weight distribution of the functional components, cocktail-type step distribution is presented similarly from low to high, micromolecules are absorbed and take effects firstly, macromolecules are absorbed later, step-by-step absorption and relaying effect taking are conducted, and thus the freeze-dried powder takes the effects more quickly and keeps the effects longer.

The invention provides a waste composite high-heat biomass fuel and an ultrasonic microwave assisted preparation method thereof. The waste composite high-heat biomass fuel is prepared from the following components in parts by dry weight: 25-35 parts of forestry and agricultural residues, 15-25 parts of household waste, 15-25 parts of sludge, 15-25 parts of excrement, 15-25 parts of pulverized coal, 15-25 parts of waste tire rubber particles and 2-10 parts of combustion improver; the combustion improver is composed of dolomite powder, black shale powder, serpentine powder, urea, potassium perchlorate, red mud, calcium peroxide, manganese oxide, strontium peroxide, zinc oxide, cerium oxide, boric sludge and ferrocene. The waste composite high-heat biomass fuel is suitable for long-time storage without peculiar smell. The waste composite high-heat biomass fuel is high in combustion temperature which can be within the range of 1450-1500 DEG C, and compared with a common biomass fuel, the combustion efficiency is improved by about 40%; the heat value of the waste composite high-heat biomass fuel can be within the range of 5200-5600 kilocalories / kilometer, and each ton of the waste composite high-heat biomass fuel is equivalent to 0.77 ton of standard coal; the combustion tail gas conforms to the national relevant regulations, the sulfur removal rate can be 98% and the nitrate removal rate can be 95%.

The invention discloses a method for making an earthtype tea set. The method comprises the following steps that: mottled earth, loess, blue earth and purple soil are respectively mixed according to the weight percent of 56 to 64 percent, 17 to 23 percent, 4 to 6 percent and 13 to 17 percent, and then are ground; water is added in to carry out stirring; slurry is calmed and filtered; sunshine is carried out; water is filtered out to form mud; billet drawing and finishing are finished; natural drying is carried out; oxidizing flame negative pressure baking is finished at 1,100 DEG C; equal to or higher than 1,110 DEG C and lower than or equal to 1,180 DEG C reducing flame positive pressure baking is carried out to generate kiln transformation; and finally, natural cooling, grinding and polishing are carried out. The earthtype tea set made by the method is firm and durable and has high drying degree, infrequent water absorption and better gas permeability after grinding and polishing; therefore, the earthtype tea set is suitable for containing tea and Pu'er tea particularly for a long time, and can prevent the tea from easy deterioration; moreover, the tea set has smooth and rounded surface, excellent hand feeling and both practicality and ornamental property.

The invention relates to 1-[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazol[4,3-d] pyridine-5-group)-4-ethoxybenzene sulfonyl]-cis-3,5-lupetazin citrate or aildenafil citrate crystal form O and a preparation method thereof. The invention also relates to a medicine compound containing aildenafil citrate crystal form O and the application thereof in preparing the medicine for treating erectile dysfunction (ED). The aildenafil citrate crystal form O is formed by the steps of: solving citrate in the distilled water and tetrahydrofuran, stirring, rising temperature, filtering, stirring filtrate, decreasing temperature, crystallizing and filtering. The aildenafil citrate crystal form O is prepared into the medicine together with the medical excipients and is applied in treating the erectile dysfunction disease.

The invention discloses a bladder-type storage tank for high concentration hydrogen peroxide, which comprises a storage tank shell body, an injection discharging component and a thin film liquid bag, wherein the injection discharging component is coaxially mounted inside the storage tank shell body; the injection discharging component is constituted of an end cover, a multi-hole pipe, a fixed disc and a support plate; the end cover and the fixed disc are respectively welded on two ends of the multi-hole pipe; the end cover is connected to a storage tank outlet flange; liquid inlet / outlet channels are respectively opened on the end cover and the fixed disc; the multi-hope pipe is provided with dense small holes in order to make sure the flow area of a propellant; the fixed disc and a support disc are used for mounting the thin film liquid bag and fixing the injection discharging component; the support disc is designed with a diffusion hole in order to prevent the thin film liquid bag from being impacted directly by the pressurized gas; and the thin film liquid bag is uniform in applied force. The advantages are that the bladder-type storage tank is suitable for storing hydrogen peroxide propellant for a long time; the hydrogen peroxide propellant and the pressurized gas are separated by the thin film liquid bag; the pressurized gas is wide in choice; and the hydrogen peroxide won't be catalyzed and decomposed by the pressurized gas.

The invention belongs to the technical field of corrosion resistant paint, and particularly relates to black rust-proof UV curing paint for an oil steel pipe. The UV curing paint comprises, by mass, 20%-40% of modified polyurethane acrylate (PUA), 10%-30% of modified acrylate, 20%-50% of monomer, 4%-10% of an adhesion promoter, 2%-8% of a photoinitiator, 0.5%-5% of a co-initiator, 0.5%-2% of black carbon powder, 0.5%-1% of a leveling agent, 0.5%-1% of a defoaming agent and 0.5%-1% of a dispersing agent. The UV curing paint not only guarantees an attractive coating on the surface of the oil steel pipe, but also guarantees that the drying speed and curing time of the paint are not affected; additionally, the producing process is simple, and a formed paint film has good covering power, adhesion, abrasion resistance, salt spray resistance and humidity resistance; and the UV curing paint can be applied to steel products, especially oil steel pipes, has a high coating efficiency, and is suitable for a plurality of coating modes such as spray coating and curtain coating.

The invention provides six-delicacy filling for dumplings and a preparation method thereof. The three-delicacy filling for the dumplings comprises pig lean meat 20-30 parts, pig backfat 20-30 parts, dried shelled shrimps 2-4 parts, Chinese chives 4-8 parts, dried scallops 5-8 parts, sea cucumbers 8-12 parts, shrimp eggs 2-4 parts, clear water 12-15 parts, dried shelled shrimp water 2-4 parts and dried scallop water 3-5 parts. The six-delicacy filling for the dumplings has multiple seafood species and enough delicate flavor and is free of fishy smell.

The invention discloses a preparation method of a magnesium alloy surface micro-arc oxidized nano self-assembling composite protective coating, and belongs to the technical field of magnesium alloy surface treatment. The method comprises the following steps: firstly performing micro-arc oxidation on a magnesium alloy matrix surface to form a porous ceramic layer, spraying modified water-based paint on the porous ceramic layer surface to form a water-based coating so as to form a composite protective coating composed of the porous ceramic layer and the water-based coating on the magnesium alloy matrix surface. The multilayer composite protective coating formed on the magnesium alloy surface has the features of good binding force, good compactness, high hardness, high corrosion resistance, high wear resistance and the like; the preparation method is simple, convenient and environment-friendly; the composite protective coating is an expected composite protective coating of the magnesium alloy application, and the protective requirement on the magnesium alloy product in severe environment is satisfied.