A cell transport box for maintaining biological cell activity

Abstract

The present invention relates to the field of bioengineering technology, and discloses a cell transport box for maintaining the activity of biological cells, comprising a cell transfer box, a test tube rack being arranged inside the cell transfer box, an outer surface of the cell transfer box being fixedly connected to a water tank, a water pump being fixedly installed on the outer surface of the cell transfer box, a quick-access component for enabling the test tube rack to be taken out conveniently and quickly being arranged inside the cell transfer box, and the test tube rack can be driven to slide out of the device as a whole during the process of opening a sealed door panel, thereby achieving multiple improvements and advantages of this structure. Firstly, this structure improves the convenience of operation, and an operator does not need to laboriously take out the test tube racks one by one, and the operator only needs to slide the sealed door panel, and the test tube rack can slide out as a whole, thereby greatly simplifying the operation steps. Secondly, since the test tube rack remains stable during the sliding out process, the risks of tilting, shaking and falling are reduced, thereby avoiding damage to the cell sample due to impact.

Description

Technical Field

[0001] The invention relates to the technical field of bioengineering, in particular to a cell transport box for maintaining the activity of biological cells. Background Art

[0002] A cell transport box is a device specially designed for transporting and preserving living cells or tissues. Its main purpose is to ensure that the cells or tissues maintain their activity during transportation so that they can be further studied or treated after arriving at their destination. Cell transport boxes have a wide range of applications in biomedical research, biotechnology, medical diagnosis and treatment.

[0003] However, with the continuous development of science and technology, some problems have gradually been exposed in existing cell transport boxes. Existing cell transport boxes usually achieve ventilation by opening ventilation holes on the box body or using mechanical ventilation. However, there is a problem that cannot be ignored in existing ventilation technology: the invasion of dust. Cell transport boxes are generally transported by different means of transportation, including land transportation, sea transportation and aircraft. No matter which means of transportation is used, dust will inevitably enter the interior of the cell transport box through the ventilation holes. These dusts are not only easy to carry bacteria, viruses and other microorganisms, but also directly contact with cells, causing physical damage to them.

[0004] When dust enters the cell transport box, it will first damage the clean environment inside the box. Because cells have extremely high requirements for the cleanliness of the environment, any tiny pollutants will cause abnormal reactions in the cells. Once the microorganisms in the dust, such as bacteria and viruses, come into contact with the cells, they will invade the cells and destroy their normal physiological functions, and even cause cell death. As a result, the cell transport box cannot guarantee the activity of biological cells when transporting them, thereby reducing the preservation effect of the cell transport box on biological cells. In addition, the dust itself also carries some chemical substances, such as heavy metals, harmful gases, etc., which are also toxic to cells.

[0005] At the same time, when the cell transport box is in use, since it is originally designed to accommodate and transport a large number of cell samples, the samples are usually placed in a test tube rack to keep them orderly and stable. However, when the test tube racks need to be overlapped to save space, in order to take out or put in the test tube rack, the operator often needs to take out the entire test tube rack from the inside of the cell transport box as a whole. This process is not only cumbersome, but also very easy to cause damage to the test tube rack and the cell samples therein when space is limited.

[0006] In order to take out the test tube rack, the operator usually needs to open the lid of the cell transport box. Due to the limited internal space of the transport box and the limited opening angle of the lid, the operator needs to be very careful when taking the test tube rack to avoid collision with the box. However, even for skilled operators, it is difficult to completely avoid collision and friction when working in a confined space. Secondly, when the test tube rack is taken out as a whole, due to the certain gaps between the overlapping test tube racks, it is difficult for the operator to stably grasp all the test tube racks at one time, which increases the risk of the test tube rack tilting, shaking or even falling during the process of taking out or putting back. Once the test tube rack tilts or shakes, the cell samples therein will be damaged due to the impact, which in turn affects the activity of the cells.

[0007] To this end, a cell transport box for maintaining the activity of biological cells is proposed. Summary of the invention

[0008] The object of the present invention is to provide a cell transport box for maintaining the activity of biological cells, so as to solve the problems raised in the above background technology.

[0009] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a cell transport box for maintaining the activity of biological cells, comprising a cell transfer box, a test tube rack is arranged inside the cell transfer box, the outer surface of the cell transfer box is fixedly connected to a water tank, a water pump is fixedly installed on the outer surface of the cell transfer box, a quick-access component for allowing the test tube rack to be taken out conveniently and quickly is arranged inside the cell transfer box, a buffer component for preventing the cell transfer box from shaking during transportation is arranged below the cell transfer box, a ventilation and dustproof component for providing air to cells and isolating dust is arranged on the outside of the cell transfer box, and a temperature control component for automatically adjusting the internal temperature of the cell transfer box is arranged on the outside of the cell transfer box.

[0010] The quick-access component includes an L-shaped groove and a sealing door plate, the L-shaped groove is symmetrically opened on the inner surface of the cell transfer box, the top and bottom of the sealing door plate are slidably connected to the inside of the L-shaped groove, the inner surface of the cell transfer box is symmetrically opened with linear grooves, the test tube rack is slidably connected to the inside of the linear grooves, the side bottom of the test tube rack is symmetrically fixedly connected to the limiting columns, the inner wall of the cell transfer box is symmetrically rotatably connected with a rotating limiting rod, the limiting columns are slidably connected to the inside of the rotating limiting rod, and a reset spring is fixedly connected between the bottom side surface of the test tube rack and the inner wall of the cell transfer box.

[0011] The ventilation and dust prevention assembly includes a ventilation shell, which is symmetrically fixedly connected to the outer surface of the cell transfer box, the inner wall of the ventilation shell is eccentrically connected with a rotating block, the inner wall of the ventilation shell is symmetrically provided with circular grooves, the surface of the rotating block is rotatably connected with blades arranged equidistantly in a ring, the inner surface of the ventilation shell is provided with an air inlet, and the inner wall of the ventilation shell is provided with an air outlet that passes through the surface of the cell transfer box.

[0012] Preferably, the buffer assembly includes two vertical spring groups, and the two vertical spring groups are respectively fixedly connected to the bottom of the cell transfer box, the bottom of the two vertical spring groups are fixedly connected to a supporting bottom plate, the ends of the two vertical spring groups that are close to each other are fixedly connected to a receiving plate, the outer surface of the receiving plate is symmetrically rotationally connected to a rotating bracket, the upper surface of the supporting bottom plate is fixedly connected to a fixed rod, the surface of the fixed rod is symmetrically slidingly connected to a sliding sleeve, the top of the sliding sleeve is rotationally connected to the bottom of the rotating bracket, the ends of the two sliding sleeves that are close to each other are fixedly connected to a transverse spring, and the transverse spring is slidably connected to the surface of the fixed rod.

[0013] Preferably, the temperature control component includes a temperature control pipe, which is fixedly connected to the outer surface of the cell transfer box on a side away from the sealing door panel, and the two ends of the temperature control pipe are respectively connected to the water tank and the water pump, and a connecting plate is fixedly connected to the inner wall of the temperature control pipe, and a temperature bag is fixedly connected to the outer surface of the connecting plate, and a valve core is fixedly connected to the surface of the temperature bag on a side away from the connecting plate.

[0014] Preferably, the rotating block is drivenly mounted on an external motor, and the external motor is electrically controlled to start and stop by an external controller, so that the output shaft of the external motor rotates to drive the rotating block to rotate.

[0015] Preferably, the cell transport box has a built-in water pipe, the water tank and the water pump are both connected to the water pipe, and the shape of the valve core is adapted to the shape of the inner wall of the temperature control pipe, achieving shape adaptation and close fit.

[0016] Preferably, the water tank has a built-in refrigeration element, and both the refrigeration element and the water pump are electrically controlled to start and stop by an external controller.

[0017] Preferably, a positioning pin is clamped between the sealing door panel and the outer surface of the cell transport box.

[0018] Preferably, ethylene glycol is provided inside the temperature bag, so that ethylene glycol can make timely changes to the temperature due to its own high temperature sensitivity.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] 1. The centrifugal force generated by the eccentrically arranged blades and the design of the air inlet deviating from the center of the circle effectively blocks the entry of impurities such as dust. By utilizing the eccentrically arranged blades, an outward centrifugal force is generated when the blades rotate, and the centrifugal force can throw dust and other impurities that attempt to enter the box through the air inlet away from the air inlet, thereby preventing dust and other impurities from entering the cell transport box. At the same time, when the airflow passes through the eccentric air inlet, the airflow will be affected by the rotation effect, further enhancing the effect of preventing dust from entering the interior of the ventilation shell.

[0021] First of all, this structure significantly improves the sealing and protection performance of the cell transport box, and effectively prevents the entry of pollutants such as dust, bacteria, and viruses. The cells can maintain a cleaner and more stable environment during transportation, thereby reducing the risk of infection and physical damage to the cells.

[0022] Secondly, this structure improves the cell preservation environment. Due to the effective isolation of dust and pollutants, cells can maintain their activity in a safer and more stable environment, which is crucial for maintaining the physiological functions of cells and the success of subsequent experiments.

[0023] In addition, by preventing the entry of impurities such as dust, cell death and damage caused by contamination are also reduced, which is of great significance for improving the survival rate of cell transportation and ensuring the quality of cell samples. It also helps to reduce experimental failures and repeated operations caused by cell damage, thereby improving the efficiency and accuracy of the experiment.

[0024] 2. When the sealed door panel is opened, the test tube rack can be driven to slide out of the device as a whole, thereby achieving multiple improvements. First, the convenience of operation is improved. The operator does not need to take out the test tube rack one by one with great effort. The operator only needs to slide the sealed door panel, and the test tube rack can slide out as a whole, thereby simplifying the operation steps. Secondly, since the test tube rack remains stable during the sliding process, the risks of tilting, shaking and falling are reduced, thereby avoiding damage to the cell sample due to impact. At the same time, since the operator is no longer required to manually take the test tube rack out of the cell transport box as a whole, the collision and friction between the test tube rack and the cell transport box are reduced, and the risk of contamination of the cell sample is also reduced, and the mistakes and repetitive labor during the operation are reduced. Since the test tube rack can slide out of the device as a whole, the operator can observe the status of the cell sample in the test tube rack more intuitively, reducing the possibility of misoperation. Since the operation process is simpler and faster, the operator's workload and fatigue are also reduced, thereby improving the operator's work efficiency.

[0025] 3. Through the ingenious coordination of the transverse spring and the vertical spring group, the cell transfer box exhibits the dual effects of horizontal shock absorption and vertical shock absorption in the overall structure, which not only enhances the stability and shock resistance of the cell transfer box, but also provides a safer and more stable environment for cells during transportation. First, it absorbs the impact force in the horizontal direction and reduces the displacement and shaking of the cell transfer box in the horizontal direction, thereby improving the stability of the cell transfer box. At the same time, the vertical spring group is responsible for absorbing the impact force in the vertical direction, effectively buffering the vibration of the cell transfer box in the vertical direction, and further enhancing the shock resistance of the cell transfer box. Since the stability and shock resistance of the cell transfer box have been improved, the physical damage and impact on the cells are reduced, thereby reducing the cell mortality rate.

[0026] 4. The movement distance of the valve core is controlled by the thermal expansion and contraction characteristics of the temperature bag itself, which significantly improves the effect of cell preservation and ensures long-term heat exchange between water and refrigeration elements, thereby maintaining a stable and suitable temperature environment, which helps to prolong the survival time of cells and improve the preservation effect of cells, providing higher quality cell samples for subsequent cell culture and experiments. Secondly, the closure of the valve core is controlled by the thermal expansion and contraction characteristics of the temperature bag, which can control the temperature more accurately and reduce the impact of temperature fluctuations on cells. It not only improves the stability during transportation, but also helps to reduce the cell mortality rate, providing more reliable cell samples for biomedical research and medical diagnosis. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 It is a three-dimensional schematic diagram of the main structure of the present invention;

[0028] Figure 2 It is a rear perspective schematic diagram of the main structure of the present invention;

[0029] Figure 3 A schematic cross-sectional perspective view of the internal connection relationship of the cache assembly of the present invention;

[0030] Figure 4 For the present invention Figure 3 Enlarged view of point A in the middle;

[0031] Figure 5 For the present invention Figure 3 Enlarged view of point B in the middle;

[0032] Figure 6 It is a cross-sectional stereoscopic schematic diagram of the connection relationship between the linear groove and the cell transport box of the present invention;

[0033] Figure 7 is a cutaway perspective schematic diagram of a cache assembly of the present invention;

[0034] Figure 8 For the present invention Figure 7 Enlarged view of point C in the middle;

[0035] Fig. 9 It is a cutaway perspective schematic diagram of the ventilation and dust prevention assembly of the present invention;

[0036] Fig.10 For the present invention Fig. 9 Enlarged view of point D in the middle;

[0037] Fig.11 It is a cutaway perspective schematic diagram of the temperature control assembly of the present invention;

[0038] Fig.12 For the present invention Fig.11 Enlarged view of point E in the middle.

[0039] In the figure:

[0040] 1. Cell transport box; 2. Test tube rack; 3. Water tank; 4. Water pump;

[0041] The quick-access assembly includes: 51, L-shaped groove; 52, sealing door plate; 53, linear groove; 54, limiting column; 55, rotating limiting rod; 56, reset spring;

[0042] The buffer assembly includes: 61, a vertical spring group; 62, a supporting bottom plate; 63, a receiving plate; 64, a rotating bracket; 65, a fixing rod; 66, a sliding sleeve; 67, a transverse spring;

[0043] The ventilation and dustproof assembly includes: 71, ventilation housing; 72, rotating block; 73, circular groove; 74, blade; 75, air inlet; 76, air outlet;

[0044] The temperature control component includes: 81, temperature control pipe; 82, connecting plate; 83, temperature bag; 84, valve core. DETAILED DESCRIPTION

[0045] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0046] See also Figures 1 to 12 As shown, an embodiment of the present invention provides:

[0047] A cell transport box for maintaining the activity of biological cells comprises a cell transport box 1, wherein the cell transport box 1 has a built-in water pipe, a water tank 3 and a water pump 4 are both connected to the water pipe, a valve core 84 is adapted to the shape of the inner wall of a temperature control pipe 81, and the shapes are adapted to each other and can be closely matched, a test tube rack 2 is arranged inside the cell transport box 1, a water tank 3 is fixedly connected to the outer surface of the cell transport box 1, a refrigeration element is built into the water tank 3, the refrigeration element and the water pump 4 are both electrically controlled to start and stop by an external controller, a water pump 4 is fixedly installed on the outer surface of the cell transport box 1, a quick-access component for enabling the test tube rack 2 to be conveniently and quickly taken out is arranged inside the cell transport box 1, a buffer component for preventing the cell transport box 1 from shaking during transportation is arranged below the cell transport box 1, a ventilation and dustproof component for providing air to cells and isolating dust is arranged on the outer side of the cell transport box 1, and a temperature control component for automatically adjusting the internal temperature of the cell transport box 1 is arranged on the outer side of the cell transport box 1.

[0048] The cache assembly includes an L-shaped groove 51 and a sealing door plate 52. The L-shaped groove 51 is symmetrically opened on the inner surface of the cell transfer box 1. The top and bottom of the sealing door plate 52 are both slidably connected to the inside of the L-shaped groove 51. A positioning pin is clamped between the sealing door plate 52 and the outer surface of the cell transfer box 1. A straight groove 53 is symmetrically opened on the inner surface of the cell transfer box 1. The test tube rack 2 is slidably connected to the inside of the straight groove 53. The side bottom of the test tube rack 2 is symmetrically fixedly connected to the limiting column 54. The inner wall of the cell transfer box 1 is symmetrically rotatably connected with a rotating limiting rod 55. The limiting columns 54 are all slidably connected to the inside of the rotating limiting rod 55. A reset spring 56 is fixedly connected between the bottom side surface of the test tube rack 2 and the inner wall of the cell transfer box 1. The stiffness coefficient of the reset spring 56 is not enough to damage the cells in the test tube rack 2, and the reset spring 56 can still rely on its own elastic force to bring the test tube rack 2 back to the cell transfer box 1.

[0049] The ventilation and dust prevention assembly includes a ventilation shell 71, which is symmetrically fixedly connected to the outer surface of the cell transfer box 1. The inner wall of the ventilation shell 71 is eccentrically connected to a rotating block 72, and the rotating block 72 is drivenly installed on an external motor. The external motor is electrically controlled to start and stop by an external controller, so that the output shaft of the external motor rotates to drive the rotating block 72 to rotate. Circular grooves 73 are symmetrically provided on the inner wall of the ventilation shell 71, and the surface of the rotating block 72 is symmetrically arranged in a ring and equidistantly connected to the blades 74. The inner surface of the ventilation shell 71 is provided with an air inlet 75, and the inner wall of the ventilation shell 71 is provided with an air outlet 76 that passes through the surface of the cell transfer box 1.

[0050] The buffer assembly includes two vertical spring groups 61, which are respectively fixedly connected to the bottom of the cell transfer box 1, and the bottom of the two vertical spring groups 61 is fixedly connected to a supporting base plate 62, and the ends of the two vertical spring groups 61 that are close to each other are fixedly connected to a receiving plate 63, and the outer surface of the receiving plate 63 is symmetrically rotatably connected to a rotating bracket 64, and the upper surface of the supporting base plate 62 is fixedly connected to a fixed rod 65, and the surface of the fixed rod 65 is symmetrically slidably connected to a sliding sleeve 66, and the top of the sliding sleeve 66 is rotatably connected to the bottom of the rotating bracket 64, and the ends of the two sliding sleeves 66 that are close to each other are fixedly connected to a transverse spring 67, and the transverse spring 67 is slidably connected to the surface of the fixed rod 65.

[0051] The temperature control component includes a temperature control pipe 81, which is fixedly connected to the outer surface of the cell transfer box 1 on the side away from the sealing door plate 52. The two ends of the temperature control pipe 81 are respectively connected to the water tank 3 and the water pump 4. A connecting plate 82 is fixedly connected to the inner wall of the temperature control pipe 81. A temperature bag 83 is fixedly connected to the outer surface of the connecting plate 82. Ethylene glycol is arranged inside the temperature bag 83, which plays a role in timely changing the temperature due to the high temperature sensitivity of ethylene glycol itself. A valve core 84 is fixedly connected to the surface of the temperature bag 83 on the side away from the connecting plate 82.

[0052] The working principle of the present invention in combination with the above is as follows:

[0053] The following is the initial state: the top of the sealing door plate 52 is located on the side of the vertical edge in the L-shaped groove 51, the test tube rack 2 is located on the side of the straight groove 53 away from the sealing door plate 52, the limit column 54 is located on the side of the rotating limit rod 55 away from the top of the cell transfer box 1, the reset spring 56 is not stretched, and the vertical spring group 61 and the transverse spring 67 are not compressed.

[0054] The following are the specific steps of the work:

[0055] Place the cells in test tube rack 2, as Figures 1 to 6 As shown, the operator manually removes the positioning pins on the surface of the sealing door panel 52 and presses the bottom surface of the sealing door panel 52. At this time, the sealing door panel 52 as a whole is subjected to the pressing force applied by the operator, and tends to move toward the water pump 4. However, because the sealing door panel 52 is restricted by the L-shaped groove 51, in order to comply with the pressing force applied by the operator, the bottom of the sealing door panel 52 slides toward the water pump 4 on the side of the horizontal edge of the L-shaped groove 51, and at the same time, the top of the sealing door panel 52 also slides toward the bottom of the cell transfer box 1 on the side of the vertical edge of the L-shaped groove 51.

[0056] like Figure 7As shown, when the bottom of the sealing door plate 52 enters the interior of the cell transport box 1, the bottom of the sealing door plate 52 will conflict with the bottom of the rotation limit rod 55, and the rotation limit rod 55 will rotate with the center as the rotation fulcrum, and then the rotation limit rod 55 will make the test tube rack 2 have the same rotation tendency through the limit column 54, but the test tube rack 2 and the limit column 54 cannot rotate due to the restriction of the straight groove 53, and then under the guidance of the straight groove 53, the test tube rack 2 converts the rotation tendency into a sliding movement away from the water pump 4. Furthermore, at this time, the test tube rack 2 slides in the linear groove 53 toward the side away from the water pump 4. When the limit column 54 slides to the top of the rotating limit rod 55, the test tube rack 2 has slid out of the cell transport box 1 as a whole. During this process, the return spring 56 is pulled by the test tube rack 2 and is in a stretched state. At this time, the test tube rack 2 is exposed to the outside world as a whole. At this time, the operator clamps the sealing door plate 52 on the surface of the cell transport box 1 again through the positioning pin, and puts the test tube containing the cells into the test tube rack 2. During the opening process, the test tube rack 2 can be driven to slide out of the device as a whole, thereby achieving multiple improvements. First, the convenience of operation is improved. The operator does not need to take out the test tube rack 2 one by one with great effort. The operator only needs to slide the sealing door panel 52, and the test tube rack 2 can slide out as a whole, thereby simplifying the operation steps. Secondly, since the test tube rack 2 remains stable during the sliding out process, the risks of tilting, shaking and falling are reduced, thereby avoiding damage to the cell sample due to impact. At the same time, since the operator is no longer required to manually take out the test tube rack 2 as a whole from the cell transport box 1, the collision and friction between the test tube rack 2 and the cell transport box 1 are reduced, and the risk of contamination of the cell sample is also reduced, and the mistakes and repeated labor during the operation are reduced. Since the test tube rack 2 can slide out of the device as a whole, the operator can observe the status of the cell sample in the test tube rack 2 more intuitively, reducing the possibility of misoperation. Moreover, since the operation process is simpler and faster, the workload and fatigue of the operator are also reduced, thereby improving the work efficiency of the operator.

[0057] like Figures 1 to 7 As shown, after the test tubes are installed, the operator removes the positioning pins. At this time, the sealing door panel 52, the test tube rack 2, the limiting column 54 and the rotating limiting rod 55 are not subjected to any external force except their own gravity, and then under the action of the elastic contraction of the reset spring 56 itself, the reset spring 56 pulls the test tube rack 2 back to the initial state. It can be seen from the above steps that when the reset spring 56 is stretched, the sealing door panel 52 is already located inside the cell transfer box 1, and then the contraction of the reset spring 56 will drive the sealing door panel 52 to return to the initial state again through the limiting column 54 and the rotating limiting rod 55. At this time, the operator clamps the sealing door panel 52 to the surface of the cell transfer box 1 again through the positioning pins. At this time, the cells have been loaded into the cell transfer box 1, and the transportation of the cell transfer box 1 can begin.

[0058] During transportation by car or train, the cell transport box 1 is often subjected to vibrations of different directions and intensities due to the complexity of road conditions and other external factors.

[0059] like Figures 3 to 5 As shown, when a vehicle passes through a bumpy road or a train passes through a rail joint, the cell transport box 1 is subjected to vertical vibration, and the vertical spring group 61 begins to play a role. At this time, the vertical spring group 61 is in a continuous compression and extension process due to external vibrations. In this process, the vertical spring group 61 converts part of the kinetic energy into elastic potential energy, thereby reducing the direct impact of the vibration on the cell transport box 1. At the same time, the vertical spring group 61 will drive the receiving plate 63 to move synchronously toward the supporting bottom plate 62 when it contracts, and the descent of the receiving plate 63 will cause the rotating bracket 64 to rotate to a certain extent, within the limit of the fixing rod 65. Under the control, the rotating bracket 64 will also push the sliding sleeve 66 to slide toward the side where the two sliding sleeves 66 are close to each other, and then in the process of the two sliding sleeves 66 sliding towards each other on the fixed rod 65, the movement of the sliding sleeve 66 will also push the transverse spring 67 and make the transverse spring 67 in a compressed state. It can be seen from the above steps that at this time, the vertical spring group 61 is constantly in a process of compression and extension due to external vibration, and then the transverse spring 67 will also be in a process of continuous compression and extension. In this process, the transverse spring 67 converts part of the kinetic energy into elastic potential energy, further reducing the direct impact of vibration on the cell transport box 1.

[0060] like Figures 3 to 5As shown, when the vehicle turns or brakes suddenly, the cell transfer box 1 is subjected to a thrust or a pull from the side, and the transverse spring 67 is responsible for handling the vibration from the horizontal direction. The transverse spring 67 transmits the vibration force to the vertical spring group 61 synchronously through the sliding sleeve 66, the rotating bracket 64, and the receiving plate 63. Then, at this time, the vertical spring group 61 and the transverse spring 67 synchronously disperse the impact force through their own elasticity, thereby reducing the horizontal shaking of the cell transfer box 1. Both vertical and horizontal vibrations will cause reasonable vertical and horizontal shock absorption of the vertical spring group 61 and the transverse spring 67, thereby better protecting the cell transfer box 1 and reducing the shaking of the cell transfer box 1. Through the ingenious cooperation of the transverse spring 67 and the vertical spring group 61, the cell The transfer box 1 exhibits dual effects of horizontal shock absorption and vertical shock absorption in its overall structure, which not only enhances the stability and shock resistance of the cell transfer box 1, but also provides a safer and more stable environment for cells during transportation. First, it absorbs the impact force in the horizontal direction, reduces the displacement and shaking of the cell transfer box 1 in the horizontal direction, thereby improving the stability of the cell transfer box 1. At the same time, the vertical spring group 61 is responsible for absorbing the impact force in the vertical direction, effectively buffering the vibration of the cell transfer box 1 in the vertical direction, and further enhancing the shock resistance of the cell transfer box 1. Since the stability and shock resistance of the cell transfer box 1 are improved, the physical damage and impact to the cells are reduced, thereby reducing the cell mortality rate.

[0061] like Fig. 9 and Fig.10 As shown, during transportation, the operator needs to electrically control the external motor to start through the external controller, and the output shaft of the external motor rotates to drive the rotating block 72 to rotate synchronously, and the rotating block 72 drives the blades 74 on its surface to rotate synchronously along the trajectory of the circular groove 73.

[0062] In terms of ventilation, since the air inlet 75 and the air outlet 76 are both offset from the center of the ventilation shell 71, when the air passes through these air outlets 76, the air will not flow in a straight line along the center of the ventilation shell 71, but will move along an inclined path. As a result, the air generates a rotational component when entering the ventilation shell 71, which helps to guide the air to pass through the ventilation shell 71 more smoothly.

[0063] At the same time, when the circular groove 73 rotates, the blades 74 fixed on the rotating block 72 rotate accordingly, and the rotating blades 74 form a dynamic rotating channel. This channel changes continuously with the rotation of the blades 74, but always maintains a certain space for air to pass through. At the same time, this inclined flow path helps to reduce the resistance to air flow, allowing air to pass through the ventilation shell 71 more smoothly.

[0064] This structure utilizes the Bernoulli principle in fluid mechanics. In an incompressible fluid, the pressure is low where the flow rate is high, and the pressure is high where the flow rate is low. As the air passes through the ventilation shell 71, its flow path is inclined and changes continuously with the rotation of the blades 74. This causes the flow rate of the air to change when passing through the ventilation shell 71. The change in flow rate leads to a change in pressure, thereby forming a dynamic pressure field. This pressure field helps to guide the air to pass through the ventilation shell 71 more smoothly, and this structure enhances the ventilation effect. Further air enters the ventilation shell 71 through the air inlet 75 and finally enters the cell transport box 1 through the air outlet 76 for cell breathing.

[0065] In terms of dust prevention, the rotation of the blades 74 inside the circular groove 73 plays a crucial role. The blades 74 not only form a dynamic barrier, but also effectively prevent dust from entering the interior of the ventilation shell 71 through the centrifugal force generated by their rotation. When the blades 74 rotate inside the circular groove 73, the blades 74 will continuously change their position relative to the rotating block 72. This rotation forms a dynamic barrier, so that when dust tries to enter the ventilation shell 71, it will encounter the constantly changing position of the blades 74, thereby increasing the difficulty of dust entry.

[0066] Secondly, since the mass of dust is greater than the mass of air, when the blades 74 rotate, the dust is more easily affected by centrifugal force, which is the outward force exerted on an object when it rotates. It pushes dust and other impurities to the side away from the air inlet 75. The effect of centrifugal force further enhances the dust-proof effect of the ventilation and dust-proof assembly.

[0067] In addition, the eccentric design of the ventilation and dust prevention assembly also plays a key role. Since the rotating block 72 deviates from the center of the ventilation shell 71, when the rotating block 72 drives the blade 74 to rotate, the blade 74 will move along an inclined path. It can be seen from the above steps that this inclined movement path helps to enhance the ventilation effect. At the same time, when the air flows, the dust is more easily affected by gravity and settles downward. The inclined path makes the dust subject to the combined effects of gravity and centrifugal force when passing through the air inlet 75. Gravity pulls the dust to the bottom of the air inlet 75, while the centrifugal force pushes the dust to the periphery of the air inlet 75. Under the dual effects of gravity and centrifugal force, it is more difficult for dust to enter the ventilation shell 71 Therefore, under the combined effect of the eccentric design and the centrifugal force, the dust-proof effect of the ventilation and dust-proof assembly is enhanced. The centrifugal force generated by the eccentrically arranged blades 74 and the design of the air inlet 75 deviating from the center of the circle effectively prevent the entry of impurities such as dust. By utilizing the eccentrically arranged blades 74, an outward centrifugal force is generated when the blades 74 rotate, and the centrifugal force can throw dust and other impurities that attempt to enter the box through the air inlet 75 away from the air inlet 75, thereby preventing dust and other impurities from entering the interior of the cell transport box 1. At the same time, when the airflow passes through the eccentric air inlet 75, the airflow will be affected by the rotation effect, further enhancing the effect of preventing dust from entering the interior of the ventilation shell 71.

[0068] First of all, this structure significantly improves the sealing and protective performance of the cell transfer box 1, and effectively prevents the entry of pollutants such as dust, bacteria, and viruses. The cells can maintain a cleaner and more stable environment during transportation, thereby reducing the risk of infection and physical damage to the cells.

[0069] Secondly, this structure improves the cell preservation environment. Due to the effective isolation of dust and pollutants, cells can maintain their activity in a safer and more stable environment, which is crucial for maintaining the physiological functions of cells and the success of subsequent experiments.

[0070] In addition, by preventing the entry of impurities such as dust, cell death and damage caused by contamination are also reduced, which is of great significance for improving the survival rate of cell transportation and ensuring the quality of cell samples. It also helps to reduce experimental failures and repeated operations caused by cell damage, thereby improving the efficiency and accuracy of the experiment.

[0071] like Figure 1 and Figure 2 As shown, during the cell transportation process, the operator needs to add water into the water tank 3, and then the operator manually controls the external controller to electrically control the refrigeration element and start the water pump 4.

[0072] During the transportation process, changes in external temperature will affect the activity of its cells. When the external temperature becomes higher, the water inside the water pipe will be affected, and the temperature of the water will become higher.

[0073] like Fig.11 and Fig.12 As shown, when the water pump 4 draws the water in the water injection pipe into the temperature control pipe 81, the water with higher temperature will pass through the connecting plate 82 and contact the temperature bag 83. In this process, due to the increase in water temperature, the temperature bag 83 will expand to a certain extent due to the heat. Since the expanded temperature bag 83 is fixedly connected to the connecting plate 82 at one end, most of the temperature bag 83 will continue to expand toward the side away from the connecting plate 82, and then the expansion of the temperature bag 83 drives the valve core 84 to move synchronously toward the water tank 3. At this time, due to the movement of the valve core 84, the gap between the valve core 84 and the inner wall of the temperature control pipe 81 gradually decreases, thereby resulting in a decrease in the water flow through the valve core 84. Further, the flow rate of water in the temperature control pipe 81 will be synchronously reduced at this time.

[0074] When the water flow rate decreases, the contact time between water molecules and the built-in refrigeration element of the water tank 3 will become longer, thereby improving the heat exchange efficiency, and the heat in the water is absorbed and transferred to the refrigeration element. Because the contact time between water and the refrigeration element increases, the water will continue to be cooled by the refrigeration element after the heat exchange, and continue to enter the built-in water pipe of the cell transport box 1 through the water tank 3, and circulate in this way to keep the water temperature in the water pipe at an appropriate temperature to ensure the activity of the cells. The movement distance of the valve core 84 is controlled by the thermal expansion and contraction characteristics of the temperature bag 83 itself, which significantly improves the cell preservation effect and ensures long-term heat exchange between the water and the refrigeration element, thereby maintaining a stable and suitable temperature environment, which helps to prolong the survival time of the cells, improve the cell preservation effect, and provide higher quality cell samples for subsequent cell culture and experiments. Secondly, the closing of the valve core 84 is controlled by the thermal expansion and contraction characteristics of the temperature bag 83, which can more accurately control the temperature and reduce the impact of temperature fluctuations on the cells. It not only improves the stability during transportation, but also helps to reduce the cell mortality rate, providing more reliable cell samples for biomedical research and medical diagnosis.

[0075] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "including one..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0076] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A cell transport box for maintaining the activity of biological cells, comprising a cell transport box (1), wherein a test tube rack (2) is arranged inside the cell transport box (1), the outer surface of the cell transport box (1) is fixedly connected to a water tank (3), and the outer surface of the cell transport box (1) is fixedly installed with a water pump (4), characterized in that: The cell transport box (1) is provided with a quick-access component for enabling the test tube rack (2) to be taken out conveniently and quickly, a buffer component is provided below the cell transport box (1) for preventing the cell transport box (1) from shaking during transportation, a ventilation and dustproof component is provided outside the cell transport box (1) for providing air to the cells and isolating dust, and a temperature control component is provided outside the cell transport box (1) for automatically adjusting the internal temperature of the cell transport box (1); The quick-access component comprises an L-shaped groove (51) and a sealing door plate (52); the L-shaped groove (51) is symmetrically opened on the inner surface of the cell transport box (1); the top and bottom of the sealing door plate (52) are both slidably connected to the inside of the L-shaped groove (51); the inner surface of the cell transport box (1) is symmetrically opened with linear grooves (53); the test tube rack (2) is slidably connected to the inside of the linear grooves (53); the side bottom of the test tube rack (2) is symmetrically fixedly connected to a limiting column (54); the inner wall of the cell transport box (1) is symmetrically rotatably connected to a rotating limiting rod (55); the limiting columns (54) are all slidably connected to the inside of the rotating limiting rod (55); and a return spring (56) is fixedly connected between the side surface of the test tube rack (2) and the inner wall of the cell transport box (1); The ventilation and dust prevention component comprises a ventilation shell (71), the ventilation shell (71) is symmetrically fixedly connected to the outer surface of the cell transfer box (1), the inner wall of the ventilation shell (71) is eccentrically rotatably connected to a rotating block (72), the inner wall of the ventilation shell (71) is symmetrically provided with circular grooves (73), the surface of the rotating block (72) is rotatably connected to blades (74) arranged equidistantly in a ring shape, the inner surface of the ventilation shell (71) is provided with an air inlet (75), and the inner wall of the ventilation shell (71) is provided with an air outlet (76) penetrating the surface of the cell transfer box (1).

2. A cell transport box for maintaining biological cell activity according to claim 1, characterized in that: The buffer assembly comprises two vertical spring groups (61), the two vertical spring groups (61) are respectively fixedly connected to the bottom of the cell transport box (1), the bottoms of the two vertical spring groups (61) are fixedly connected to a supporting base plate (62), the adjacent ends of the two vertical spring groups (61) are fixedly connected to a receiving plate (63), the outer surface of the receiving plate (63) is symmetrically rotatably connected to a rotating bracket (64), the upper surface of the supporting base plate (62) is fixedly connected to a fixing rod (65), the surface of the fixing rod (65) is symmetrically slidably connected to a sliding sleeve (66), the top of the sliding sleeve (66) is rotatably connected to the bottom of the rotating bracket (64), the adjacent ends of the two sliding sleeves (66) are fixedly connected to a transverse spring (67), and the transverse spring (67) is slidably connected to the surface of the fixing rod (65).

3. A cell transport box for maintaining biological cell activity according to claim 1, characterized in that: The temperature control component comprises a temperature control pipe (81), wherein the temperature control pipe (81) is fixedly connected to the outer surface of a side of the cell transport box (1) away from the sealing door plate (52), and the two ends of the temperature control pipe (81) are respectively connected to the water tank (3) and the water pump (4), and a connecting plate (82) is fixedly connected to the inner wall of the temperature control pipe (81), and a temperature bag (83) is fixedly connected to the outer surface of the connecting plate (82), and a valve core (84) is fixedly connected to the surface of the temperature bag (83) away from the connecting plate (82).

4. A cell transport box for maintaining biological cell activity according to claim 1, characterized in that: The rotating block (72) is drivenly mounted on an external motor, and the external motor is electrically controlled to start and stop by an external controller.

5. The cell transport box for maintaining biological cell activity according to claim 3, characterized in that: The cell transport box (1) has a built-in water pipeline, the water tank (3) and the water pump (4) are both connected to the water pipeline, and the shape of the valve core (84) is compatible with the shape of the inner wall of the temperature control pipeline (81).

6. The cell transport box for maintaining biological cell activity according to claim 1, characterized in that: The water tank (3) has a built-in refrigeration element, and both the refrigeration element and the water pump (4) are electrically controlled to start and stop by an external controller.

7. The cell transport box for maintaining biological cell activity according to claim 1, characterized in that: A positioning pin is clamped between the sealing door plate (52) and the outer surface of the cell transport box (1).

8. The cell transport box for maintaining biological cell activity according to claim 3, characterized in that: Ethylene glycol is arranged inside the temperature bag (83).

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