Preparation method of medical modified starch

Abstract

The invention discloses a preparation method of medical modified starch, which comprises the following steps: S1, putting native starch and deionized water into a mixing device, and stirring to prepare native starch slurry; s2, regulating the temperature of the raw starch slurry through a heat exchanger, wherein the reaction temperature is 40-58 DEG C; s3, adjusting the pH value of the native starch slurry to 8.2-9.8 by using sodium hydroxide, keeping the temperature at 35-60 DEG C, adding a cross-linking agent and succinic anhydride, uniformly stirring, and standing to react for 1-3 hours; s4, adding an etherifying agent for etherification reaction; s5, adding hydrochloric acid to adjust the pH value to 6.5-7.5; s6, selenium-enriched yeast and carrageenan are sequentially added, and stirring is conducted for 40-60 min at the temperature of 25-30 DEG C; and S7, adding procyanidine and trace elements, stirring for 0.5-1 hour, and drying in a drying device to obtain the medical modified starch. According to the invention, the reaction conditions are optimized, the reaction efficiency is improved, the reaction time is shortened, the production efficiency is improved, and the preparation method is simple and easy for industrial production and application.

Description

Technical Field

[0001] The invention relates to the technical field of modified starch preparation, and in particular to a method for preparing medical modified starch. Background Art

[0002] Starch is the largest storage carbohydrate in cereal grains and a polysaccharide. Starch is a raw material with thermoplastic properties and a degradable molecular structure. However, due to its poor water solubility, its chemical application is greatly limited, so modified starch is often used. Natural starch is properly chemically treated to introduce certain chemical groups to change its molecular structure or its physical and chemical properties, thereby generating modified starch. Modified starch is widely used in food, medicine and health, agriculture, papermaking, printing, cosmetics, detergents, adhesives and other industries.

[0003] The existing modified starch preparation reaction efficiency is low, the reaction time is long, and the production efficiency is low. Summary of the invention

[0004] The problem to be solved by the present invention is to provide a method for preparing modified starch for medicine, which optimizes reaction conditions, improves reaction efficiency, shortens reaction time, improves production efficiency, and is simple in preparation method and easy to be applied in industrial production. The present invention prepares modified starch by adding a cross-linking agent to native starch and succinic anhydride, and composites the modified starch with trace elements to prepare composite modified starch with higher nutritional value. At the same time, acidification and etherification treatment are used to introduce new functional groups into starch molecules or change the size of starch molecules and the properties of starch particles, thereby changing the natural properties of starch and making it more suitable for the application requirements of food gel candies, jellies and hollow capsules for medicine.

[0005] The technical solution provided by the present invention to solve the above problems is: a method for preparing modified starch for medicine, comprising the following raw materials in parts by weight: 50-70 parts of native starch, 0.01-0.05 parts of trace elements, 5-35 parts of deionized water, 0.01-0.1 parts of hydrochloric acid, 0.01-0.1 parts of sodium hydroxide, 2-4 parts of etherifying agent, 4-10 parts of cross-linking agent, 0.1-0.5 parts of succinic anhydride, 5-8 parts of selenium-enriched yeast, 6-8 parts of proanthocyanidins, and 4-6 parts of carrageenan;

[0006] The preparation method comprises the following steps:

[0007] S1, putting raw starch and deionized water into a mixing device and stirring to prepare raw starch slurry;

[0008] S2, adjusting the temperature of the raw starch slurry through a heat exchanger, the reaction temperature is 40-58°C;

[0009] S3, using sodium hydroxide to adjust the pH of the original starch slurry to 8.2-9.8, maintaining the temperature at 35-60° C., adding a cross-linking agent and succinic anhydride, stirring evenly, and allowing to react for 1-3 hours;

[0010] S4, adding an etherifying agent to carry out etherification reaction;

[0011] S5. Add hydrochloric acid to adjust the pH to 6.5-7.5;

[0012] S6, add selenium-enriched yeast and carrageenan in sequence, and stir at a temperature of 25-30°C for 40-60 minutes;

[0013] S7. Add proanthocyanidins and trace elements, stir for 0.5 to 1 hour, and dry in a drying device to obtain medical modified starch.

[0014] Preferably, the raw materials include the following parts by weight: 50 parts of native starch, 0.01 parts of trace elements, 25 parts of deionized water, 0.03 parts of hydrochloric acid, 0.05 parts of sodium hydroxide, 2 parts of etherifying agent, 6 parts of cross-linking agent, 0.3 parts of succinic anhydride, 6 parts of selenium-enriched yeast, 6 parts of proanthocyanidins, and 6 parts of carrageenan.

[0015] Preferably, the raw materials include the following parts by weight: 60 parts of native starch, 0.03 parts of trace elements, 30 parts of deionized water, 0.01 parts of hydrochloric acid, 0.04 parts of sodium hydroxide, 3 parts of etherifying agent, 10 parts of cross-linking agent, 0.1 parts of succinic anhydride, 5 parts of selenium-enriched yeast, 8 parts of proanthocyanidins, and 4 parts of carrageenan.

[0016] Preferably, the raw materials include the following parts by weight: 70 parts of native starch, 0.05 parts of trace elements, 35 parts of deionized water, 0.08 parts of hydrochloric acid, 0.1 parts of sodium hydroxide, 4 parts of etherifying agent, 4 parts of cross-linking agent, 0.5 parts of succinic anhydride, 8 parts of selenium-enriched yeast, 7 parts of proanthocyanidins, and 5 parts of carrageenan.

[0017] Preferably, the native starch is one or a combination of waxy corn starch, corn starch, potato starch or cassava starch.

[0018] Preferably, the trace element is one or a combination of multiple elements selected from the group consisting of Zn, Fe and Ga.

[0019] Preferably, the etherifying agent is propylene oxide.

[0020] Preferably, in S1, the concentration of the native starch slurry is controlled to be 25 to 30 degrees Baume.

[0021] Preferably, the stirring time in S1 is 40 to 60 minutes.

[0022] Preferably, the stirring speed in S1 is 60 r / min, and the stirring temperature is 40-50°C.

[0023] Compared with the prior art, the invention has the following advantages: the invention optimizes the reaction conditions, improves the reaction efficiency, shortens the reaction time, improves the production efficiency, and has a simple preparation method, which is easy to carry out industrial production and application; the invention prepares modified starch by adding a cross-linking agent to native starch and succinic anhydride, and composites the modified starch with trace elements to prepare composite modified starch with higher nutritional value; and at the same time, by acidification and etherification treatment, new functional groups are introduced into starch molecules or the size of starch molecules and the properties of starch particles are changed, thereby changing the natural properties of starch and making it more suitable for the application requirements of food gel candies, jellies and medicinal hollow capsules. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The drawings described herein are used to provide further understanding of the present invention and constitute a part of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute improper limitations on the present invention.

[0025] Figure 1 It is a flowchart of the preparation method of the present invention;

[0026] Figure 2 It is a schematic diagram of the three-dimensional structure of the drying device of the present invention;

[0027] Figure 3 is a front view of the outer cylinder of the drying device of the present invention;

[0028] Figure 4 yes Figure 3 The enlarged schematic diagram of point A in the middle;

[0029] Figure 5 is a cross-sectional view of an inner cylinder of a drying device of the present invention;

[0030] Figure 6 yes Figure 5 The enlarged schematic diagram of point B in the middle;

[0031] Figure 7 is a top view of the inner cylinder of the drying device of the present invention;

[0032] Figure 8 is a cross-sectional view of an outer cylinder of a drying device of the present invention;

[0033] Fig. 9 yes Figure 8 Enlarged schematic diagram of point C in the middle.

[0034] The attached drawings are marked with: 1. frame, 2. fixing plate, 3. bolt, 4. outer cylinder, 5. support seat, 6. rotating wheel, 7. mounting hole, 8. fixing frame, 9. screening net one, 10. notch groove, 11. positioning rod, 12. positioning strip, 13. arc rod, 14. bristles, 15. positioning frame, 16. positioning groove, 17. heating layer, 18. support rod, 19. screening net two. DETAILED DESCRIPTION

[0035] The following will describe the implementation methods of the present invention in detail with reference to the accompanying drawings and embodiments, so that the implementation process of how the present invention applies technical means to solve technical problems and achieve technical effects can be fully understood and implemented accordingly.

[0036] In the description of the present invention, it should be noted that directional words, such as the terms "center", "lateral", "longitudinal", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", etc., indicating directions and positional relationships are based on the directions or positional relationships shown in the accompanying drawings, which are only for the convenience of narrating the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and cannot be understood as limiting the specific scope of protection of the present invention.

[0037] In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features. Therefore, the definition of "first" and "second" features can explicitly or implicitly include one or more of the features. In the description of the present invention, the meaning of "several" is two or more, unless otherwise clearly and specifically defined.

[0038] In the present invention, unless otherwise specified and limited, the terms "assemble", "connect", and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can also be a mechanical connection; it can be directly connected, or it can be connected through an intermediate medium, or the two elements can be internally connected. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0039] It should be understood that when used in this specification and the appended claims, the terms "include" and "comprises" indicate the presence of described features, integers, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, integers, steps, operations, elements, components and / or combinations thereof.

[0040] It should also be understood that the terms used in this description of the embodiments of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the embodiments of the present invention. As used in the description of the embodiments of the present invention and the appended claims, unless the context clearly indicates otherwise, the singular forms of "a", "an" and "the" are intended to include plural forms.

[0041] Example 1

[0042] The present embodiment discloses a method for preparing modified starch for medical use, comprising the following raw materials in parts by weight: 50-70 parts of native starch, 0.01-0.05 parts of trace elements, 5-35 parts of deionized water, 0.01-0.1 parts of hydrochloric acid, 0.01-0.1 parts of sodium hydroxide, 2-4 parts of etherifying agent, 4-10 parts of cross-linking agent, 0.1-0.5 parts of succinic anhydride, 5-8 parts of selenium-enriched yeast, 6-8 parts of proanthocyanidins, and 4-6 parts of carrageenan; wherein the native starch is a combination of one or more of waxy corn starch, corn starch, potato starch or cassava starch; the trace elements are a combination of one or more of Zn, Fe and Ga; the etherifying agent is propylene oxide.

[0043] The preparation method comprises the following steps:

[0044] S1. Put the raw starch and deionized water into a mixing device and stir to form raw starch slurry. The stirring time is 40 to 60 minutes, the stirring speed is 60 r / min, and the stirring temperature is 40 to 50° C. The concentration of the raw starch slurry is controlled to be 25 to 30 degrees Baume;

[0045] S2, adjusting the temperature of the raw starch slurry through a heat exchanger, the reaction temperature is 40-58°C;

[0046] S3, using sodium hydroxide to adjust the pH of the original starch slurry to 8.2-9.8, maintaining the temperature at 35-60° C., adding a cross-linking agent and succinic anhydride, stirring evenly, and allowing to react for 1-3 hours;

[0047] S4, adding an etherifying agent to carry out etherification reaction;

[0048] S5. Add hydrochloric acid to adjust the pH to 6.5-7.5;

[0049] S6, add selenium-enriched yeast and carrageenan in sequence, and stir at a temperature of 25-30°C for 40-60 minutes;

[0050] S7. Add proanthocyanidins and trace elements, stir for 0.5 to 1 hour, and dry in a drying device to obtain medical modified starch.

[0051] Example 2

[0052] The present embodiment discloses a method for preparing a modified starch for medical use, comprising the following raw materials in parts by weight: 50 parts of native starch, 0.01 parts of trace elements, 25 parts of deionized water, 0.03 parts of hydrochloric acid, 0.05 parts of sodium hydroxide, 2 parts of an etherifying agent, 6 parts of a cross-linking agent, 0.3 parts of succinic anhydride, 6 parts of selenium-enriched yeast, 6 parts of proanthocyanidins, and 6 parts of carrageenan; wherein the native starch is a combination of one or more of waxy corn starch, corn starch, potato starch, or cassava starch; the trace elements are a combination of one or more of Zn, Fe, and Ga; the etherifying agent is propylene oxide;

[0053] The preparation method comprises the following steps:

[0054] S1. Put the raw starch and deionized water into a mixing device and stir to form raw starch slurry. The stirring time is 40 to 60 minutes, the stirring speed is 60 r / min, and the stirring temperature is 40 to 50° C. The concentration of the raw starch slurry is controlled to be 25 to 30 degrees Baume;

[0055] S2, adjusting the temperature of the raw starch slurry through a heat exchanger, the reaction temperature is 40-58°C;

[0056] S3, using sodium hydroxide to adjust the pH of the original starch slurry to 8.2-9.8, maintaining the temperature at 35-60° C., adding a cross-linking agent and succinic anhydride, stirring evenly, and allowing to react for 1-3 hours;

[0057] S4, adding an etherifying agent to carry out etherification reaction;

[0058] S5. Add hydrochloric acid to adjust the pH to 6.5-7.5;

[0059] S6, add selenium-enriched yeast and carrageenan in sequence, and stir at a temperature of 25-30°C for 40-60 minutes;

[0060] S7. Add proanthocyanidins and trace elements, stir for 0.5 to 1 hour, and dry in a drying device to obtain medical modified starch.

[0061] Example 3

[0062] The present embodiment discloses a method for preparing a modified starch for medical use, comprising the following raw materials in parts by weight: 60 parts of native starch, 0.03 parts of trace elements, 30 parts of deionized water, 0.01 parts of hydrochloric acid, 0.04 parts of sodium hydroxide, 3 parts of an etherifying agent, 10 parts of a cross-linking agent, 0.1 parts of succinic anhydride, 5 parts of selenium-enriched yeast, 8 parts of proanthocyanidins, and 4 parts of carrageenan; wherein the native starch is a combination of one or more of waxy corn starch, corn starch, potato starch, or cassava starch; the trace elements are a combination of one or more of Zn, Fe, and Ga; the etherifying agent is propylene oxide;

[0063] The preparation method comprises the following steps:

[0064] S1. Put the raw starch and deionized water into a mixing device and stir to form raw starch slurry. The stirring time is 40 to 60 minutes, the stirring speed is 60 r / min, and the stirring temperature is 40 to 50° C. The concentration of the raw starch slurry is controlled to be 25 to 30 degrees Baume;

[0065] S2, adjusting the temperature of the raw starch slurry through a heat exchanger, the reaction temperature is 40-58°C;

[0066] S3, using sodium hydroxide to adjust the pH of the original starch slurry to 8.2-9.8, maintaining the temperature at 35-60° C., adding a cross-linking agent and succinic anhydride, stirring evenly, and allowing to react for 1-3 hours;

[0067] S4, adding an etherifying agent to carry out etherification reaction;

[0068] S5. Add hydrochloric acid to adjust the pH to 6.5-7.5;

[0069] S6, add selenium-enriched yeast and carrageenan in sequence, and stir at a temperature of 25-30°C for 40-60 minutes;

[0070] S7. Add proanthocyanidins and trace elements, stir for 0.5 to 1 hour, and dry in a drying device to obtain medical modified starch.

[0071] Example 4

[0072] The present embodiment discloses a method for preparing a modified starch for medical use, comprising the following raw materials in parts by weight: 70 parts of native starch, 0.05 parts of trace elements, 35 parts of deionized water, 0.08 parts of hydrochloric acid, 0.1 parts of sodium hydroxide, 4 parts of an etherifying agent, 4 parts of a cross-linking agent, 0.5 parts of succinic anhydride, 8 parts of selenium-enriched yeast, 7 parts of proanthocyanidins, and 5 parts of carrageenan; wherein the native starch is a combination of one or more of waxy corn starch, corn starch, potato starch, or cassava starch; the trace elements are a combination of one or more of Zn, Fe, and Ga; the etherifying agent is propylene oxide;

[0073] The preparation method comprises the following steps:

[0074] S1. Put the raw starch and deionized water into a mixing device and stir to form raw starch slurry. The stirring time is 40 to 60 minutes, the stirring speed is 60 r / min, and the stirring temperature is 40 to 50° C. The concentration of the raw starch slurry is controlled to be 25 to 30 degrees Baume;

[0075] S2, adjusting the temperature of the raw starch slurry through a heat exchanger, the reaction temperature is 40-58°C;

[0076] S3, using sodium hydroxide to adjust the pH of the original starch slurry to 8.2-9.8, maintaining the temperature at 35-60° C., adding a cross-linking agent and succinic anhydride, stirring evenly, and allowing to react for 1-3 hours;

[0077] S4, adding an etherifying agent to carry out etherification reaction;

[0078] S5. Add hydrochloric acid to adjust the pH to 6.5-7.5;

[0079] S6, add selenium-enriched yeast and carrageenan in sequence, and stir at a temperature of 25-30°C for 40-60 minutes;

[0080] S7. Add proanthocyanidins and trace elements, stir for 0.5 to 1 hour, and dry in a drying device to obtain medical modified starch.

[0081] Example 5

[0082] This embodiment discloses a drying device, which is applied to S6 of Embodiments 1-4, and specifically includes a frame 1, a drying cylinder and a driving assembly;

[0083] The drying cylinder is rotatably arranged on the frame 1, and the driving assembly is installed on the frame 1 to drive the drying cylinder to rotate;

[0084] The drying cylinder comprises an inner cylinder and an outer cylinder 4, wherein the inner cylinder is detachably mounted inside the outer cylinder 4 and can rotate along with the outer cylinder 4, and sieve holes are arranged on the inner cylinder, and the inner cylinder is used for placing the modified starch to be dried.

[0085] In the above scheme, the drying cylinder is composed of an inner cylinder and an outer cylinder, and the inner cylinder is used to place the modified starch to be dried. During the rotational drying process of the drying cylinder, the powdered modified starch in the inner cylinder is dried and enters the outer cylinder through the sieve holes on the inner cylinder, while the agglomerated modified starch remains in the inner cylinder, which can effectively improve the drying efficiency.

[0086] In this embodiment, the inner cylinder includes a fixing frame 8 and a screening net 9, the fixing frame 8 is cylindrical, the screening net 9 is wound and installed on the fixing frame 8, and the sieve holes are arranged on the screening net 9.

[0087] In this embodiment, further, a mounting hole 7 is provided on the side wall of the outer cylinder 4, and the fixing frame 8 can pass through the mounting hole 7 to enter the inner part of the outer cylinder 4, and a plurality of axial support rods 18 are provided inside the outer cylinder 4, and the plurality of support rods 18 are arranged in an annular shape, and the support rods 18 contact the screening net 9 to position the screening net 9. Furthermore, the fixing method between the inner cylinder and the outer cylinder is specifically as follows: a fixing plate 2 is provided at one end of the fixing frame 8, and a through hole is provided on the fixing plate 2, and a bolt 3 hole is provided at a position corresponding to the through hole on the side wall of the outer cylinder 4, and the inner cylinder and the outer cylinder 4 are fixed by the bolt 3 passing through the through hole and being threadedly connected with the bolt 3 hole.

[0088] In the above scheme, when the inner tube is inserted into the outer tube from the mounting hole, the screening net on the inner tube contacts the support rod in the outer tube, and the support rod provides a positioning for the inner tube. Then, the inner tube can be installed into the outer tube by tightening the bolts.

[0089] In this embodiment, a notch groove 10 is provided on the inner tube, axial positioning rods 11 are provided on the groove walls on both sides of the notch groove 10, and positioning strips 12 are provided on the positioning rods 11. An axial positioning frame 15 is provided in the outer tube 4, and positioning grooves 16 cooperating with the positioning strips 12 are provided on both sides of the positioning frame 15.

[0090] Furthermore, a second screening net 19 is provided on the positioning frame 15 , and screening holes are provided on the second screening net 19 . The aperture of the screening holes on the second screening net 19 is consistent with the aperture of the screening holes on the first screening net 9 .

[0091] In the above scheme, through the cooperation of the positioning groove on the positioning frame and the positioning strip on the positioning rod, on the one hand, the rotation positioning of the inner cylinder is realized to prevent the inner cylinder from rotating relative to the outer cylinder during the process of following the rotation of the outer cylinder; on the other hand, a second screening net is arranged on the positioning frame, and the starch can also be screened through the second screening net, thereby improving the screening efficiency of the starch by the inner cylinder. At the same time, the starch to be dried can be conveniently placed in the inner cylinder through the notch groove. In the process of installing the inner cylinder into the outer cylinder, the notch groove can be closed through the cooperation between the positioning frame and the positioning rod. In the process of taking out the inner cylinder, the positioning frame is separated from the positioning rod, and the notch groove can be opened, thereby improving the efficiency of loading, unloading and cleaning.

[0092] Since some agglomerated starch in the inner cylinder will block the second screening net during the screening process, affecting the screening efficiency of the second screening net for starch, in this embodiment, further, a cleaning component for cleaning the second screening net 19 is provided on the inner cylinder at the notch groove 10. The cleaning component includes an arc rod 13 and bristles 14, the arc rod 13 is installed at the notch groove 10, the bristles 14 are fixedly arranged on the arc rod 13, and the end of the bristles 14 away from the arc rod 13 can contact the inner surface of the second screening net 19.

[0093] In the above scheme, during the process of installing or removing the inner cylinder, the bristles will scrape the inner surface of the screening net 2 to scrape off the starch blocking the screen holes on the screening net 2. Therefore, the screening efficiency of the screening net 2 for starch can be effectively guaranteed. This scheme improves work efficiency by automatically cleaning the screening net 2 during the process of installing or removing the inner cylinder.

[0094] In this embodiment, the driving assembly includes a motor and a driving shaft, the motor is mounted on the frame 1, one end of the driving shaft is connected to the output end of the motor, and the other end is fixedly connected to the outer cylinder 4. The specific installation method of the drying cylinder is as follows: a support seat 5 is provided on the frame 1, a rotatable wheel 6 is provided on the support seat 5, one end of the outer cylinder 4 is rotatably connected to the frame 1, and the other end is contacted and connected with the surface of the wheel 6.

[0095] The above description is only for the best embodiment of the present invention, but it should not be understood as limiting the claims. The present invention is not limited to the above embodiments, and its specific structure is allowed to be changed. All changes made within the scope of protection of the independent claims of the present invention are within the scope of protection of the present invention.

Claims

1. A method for preparing modified starch for medical use, characterized in that: The invention comprises the following raw materials in parts by weight: 50-70 parts of native starch, 0.01-0.05 parts of trace elements, 5-35 parts of deionized water, 0.01-0.1 parts of hydrochloric acid, 0.01-0.1 parts of sodium hydroxide, 2-4 parts of etherifying agent, 4-10 parts of cross-linking agent, 0.1-0.5 parts of succinic anhydride, 5-8 parts of selenium-enriched yeast, 6-8 parts of proanthocyanidins, and 4-6 parts of carrageenan; The preparation method comprises the following steps: S1, putting raw starch and deionized water into a mixing device and stirring to prepare raw starch slurry; S2, adjusting the temperature of the raw starch slurry through a heat exchanger, the reaction temperature is 40-58°C; S3, using sodium hydroxide to adjust the pH of the original starch slurry to 8.2-9.8, maintaining the temperature at 35-60° C., adding a cross-linking agent and succinic anhydride, stirring evenly, and allowing to react for 1-3 hours; S4, adding an etherifying agent to carry out etherification reaction; S5. Add hydrochloric acid to adjust the pH to 6.5-7.5; S6, add selenium-enriched yeast and carrageenan in sequence, and stir at a temperature of 25-30°C for 40-60 minutes; S7. Add proanthocyanidins and trace elements, stir for 0.5 to 1 hour, and dry in a drying device to obtain medical modified starch.

2. The method for preparing a modified starch for medical use according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 50 parts of native starch, 0.01 parts of trace elements, 25 parts of deionized water, 0.03 parts of hydrochloric acid, 0.05 parts of sodium hydroxide, 2 parts of etherifying agent, 6 parts of cross-linking agent, 0.3 parts of succinic anhydride, 6 parts of selenium-enriched yeast, 6 parts of proanthocyanidins and 6 parts of carrageenan.

3. The method for preparing a modified starch for medical use according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 60 parts of native starch, 0.03 parts of trace elements, 30 parts of deionized water, 0.01 parts of hydrochloric acid, 0.04 parts of sodium hydroxide, 3 parts of etherifying agent, 10 parts of cross-linking agent, 0.1 parts of succinic anhydride, 5 parts of selenium-enriched yeast, 8 parts of proanthocyanidins and 4 parts of carrageenan.

4. The method for preparing a modified starch for medical use according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 70 parts of native starch, 0.05 parts of trace elements, 35 parts of deionized water, 0.08 parts of hydrochloric acid, 0.1 parts of sodium hydroxide, 4 parts of etherifying agent, 4 parts of cross-linking agent, 0.5 parts of succinic anhydride, 8 parts of selenium-enriched yeast, 7 parts of proanthocyanidins and 5 parts of carrageenan.

5. The method for preparing a modified starch for medical use according to claim 1, characterized in that: The native starch is one or a combination of waxy corn starch, corn starch, potato starch or cassava starch.

6. The method for preparing a modified starch for medical use according to claim 1, characterized in that: The trace elements are one or a combination of multiple elements selected from Zn, Fe and Ga.

7. The method for preparing a modified starch for medical use according to claim 1, characterized in that: The etherifying agent is propylene oxide.

8. The method for preparing a modified starch for medicine according to claim 1, characterized in that: In the S1, the concentration of the native starch slurry is controlled to be 25 to 30 degrees Baume.

9. The method for preparing a modified starch for medicine according to claim 1, characterized in that: The stirring time in S1 is 40 to 60 minutes.

10. The method for preparing a modified starch for medicine according to claim 1, characterized in that: The stirring speed in S1 is 60 r / min, and the stirring temperature is 40-50°C.

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