Rehabilitation stimulation method and equipment for recovery of eye dyskinesia

Abstract

The invention discloses a rehabilitation stimulation method and device for eye dyskinesia recovery. The method comprises the steps that eye movement information of the healthy side of a patient is collected in real time; preprocessing the collected eye movement information of the healthy side of the patient; analyzing the preprocessed eye movement information of the unhealthy side of the patient, and predicting that the eyes of the unhealthy side of the patient are in any movement mode of non-autonomous blinking, autonomous eye closing, long-time eye closing and forceful blinking; according to the predicted eye movement mode of the uninjured side of the patient, generating a stimulation waveform corresponding to the mode; and sending the stimulation waveform to a stimulation electrode on the affected side of the patient. For a facial paralysis patient, the eye movement of the affected side and the healthy side is realized by identifying the healthy side eye, acquiring the corresponding eye movement mode, generating the stimulation waveform and sending the stimulation waveform to the stimulation electrode.

Description

Technical Field

[0001] The present invention belongs to the technical field of rehabilitation stimulation, and in particular relates to a rehabilitation stimulation method and device for recovery of eye movement disorders. Background Art

[0002] The nervous system is divided into the central nervous system and the peripheral nervous system. The facial nerve belongs to the seventh of the 12 pairs of cranial nerves in the peripheral nervous system.

[0003] The motor dysfunction of facial expression muscles caused by facial nerve lesions is called "facial paralysis", which is manifested as loss of static and dynamic expressions on one side of the face, facial asymmetry, incomplete closure, etc. In severe cases, the eyelids cannot close, leading to the risk of dry cornea, inflammation and even blindness.

[0004] Therefore, patients with damaged facial nerves need to restore functions such as closing the eyes as soon as possible through surgery, medication, or massage.

[0005] Now, through neurosurgery, nerve anastomosis surgery can be used to directly connect the nerves, or the upper and lower eyelids can be directly sutured, and erythromycin eye ointment can be directly applied to the affected eye.

[0006] However, the existing methods have the following defects: they sever normal nerves, robbing Peter to pay Paul, and the muscles controlled by the original nerves will lose motor control; the nerve's motor consciousness comes from the motor control signal of the donor site, which will produce unexpected muscle movement; the operation time is long and the risk is relatively high, as the donor nerve must be stripped and transferred to the recipient nerve; it is very easy to cause the formation of neuroma in the donor area and the loss of sensory and motor functions; for complex severed and anastomosed nerve bundles, the terminal muscle motor control recovery is poor; the anastomosis technique that uses a bridge to reduce tension is limited by the length of the bridge, affecting the future survival rate; postoperative rehabilitation training is complicated and the patient's cooperation is poor.

[0007] For patients whose nerve signal transmission is interrupted due to nerve severance or nerve necrosis caused by trauma, inflammation, tumors, surgery, etc., nerve anastomosis must be used for recovery. The facial nerve has a total of five branches, each of which controls muscle movements in the forehead, around the eyes, cheeks, mouth and mandible. For the movement of the facial nerve that controls the eyelid and orbital muscles (orbicularis oculi muscle) after damage, it can be achieved through brain-computer interface technology, through implanted or transcutaneous electrode stimulation. Summary of the invention

[0008] In order to solve the above technical problems, the present invention proposes a rehabilitation stimulation method and device for recovery of ocular movement disorders.

[0009] In order to achieve the above object, the technical solution of the present invention is as follows:

[0010] In one aspect, the present invention discloses a rehabilitation stimulation method for recovery of ocular movement disorders, comprising:

[0011] Step S1: collecting eye movement information of the healthy side of the patient in real time;

[0012] Step S2: preprocessing the collected eye movement information of the healthy side of the patient;

[0013] Step S3: analyzing the pre-processed eye movement information of the healthy side of the patient, and predicting whether the eye of the healthy side of the patient is in any movement mode of involuntary blinking, voluntary eye closure, long-term eye closure, or forced eye blinking;

[0014] Step S4: generating a stimulation waveform corresponding to the predicted eye movement pattern of the healthy side of the patient;

[0015] Step S5: Send the stimulation waveform to the stimulation electrode on the affected side of the patient.

[0016] Based on the above technical solution, the following improvements can be made:

[0017] As a preferred solution, step S1 collects eye movement information of the healthy side in real time by one or more of the following methods;

[0018] Method 1: Using implantable neural electrodes to collect neural electrical signals from the branches of the facial nerve that controls the movement of the orbicularis oculi muscle for eye closing;

[0019] Method 2: Using transcutaneous muscle electrodes to collect the electromyographic signals of the orbicularis oculi muscle that controls the eye closing movement;

[0020] Method 3: Use an image acquisition device to acquire the side image of the eye on the healthy side.

[0021] As a preferred solution, the preprocessing operation in step S2 includes: filtering, removing artifacts, and setting a baseline for the neural electrical signal or the electromyographic signal; or filtering and de-jittering the side eye image.

[0022] As a preferred solution, the stimulation electrode on the affected side is percutaneously or implanted to stimulate the orbicularis oculi muscle and / or nerve that controls the eye closing movement.

[0023] As a preferred solution, the implantable stimulation electrode is a columnar electrode or a filamentary spiral electrode.

[0024] In addition, in another aspect, the present invention further discloses a rehabilitation stimulation device for recovery of ocular movement disorders, comprising:

[0025] Eye movement information collection module, used to collect eye movement information of the healthy side of the patient in real time;

[0026] A preprocessing module, used for preprocessing the collected eye movement information of the healthy side of the patient;

[0027] An analysis and processing module is used to analyze the pre-processed eye movement information of the healthy side of the patient, and predict whether the eye of the healthy side of the patient is in any movement mode of involuntary blinking, voluntary eye closure, long-term eye closure, or forced eye blinking;

[0028] A stimulation waveform generation module, used for generating a stimulation waveform corresponding to the pattern according to the predicted eye movement pattern of the healthy side of the patient;

[0029] The stimulation waveform sending module is used to send the stimulation waveform to the stimulation electrode on the affected side of the patient.

[0030] As a preferred solution, the eye movement information acquisition module acquires the eye movement information of the healthy side in real time by one or more of the following methods:

[0031] Method 1: Using implantable neural electrodes to collect neural electrical signals from the branches of the facial nerve that controls the movement of the orbicularis oculi muscle for eye closing;

[0032] Method 2: Using transcutaneous muscle electrodes to collect the electromyographic signals of the orbicularis oculi muscle that controls the eye closing movement;

[0033] Method 3: Use an image acquisition device to acquire the side image of the eye on the healthy side.

[0034] As a preferred solution, the preprocessing operations in the preprocessing module include: filtering, removing artifacts, and setting a baseline for neural electrical signals or electromyographic signals; or filtering and removing jitter for side eye images.

[0035] As a preferred solution, the stimulation electrode on the affected side is percutaneously or implanted to stimulate the orbicularis oculi muscle and / or nerve that controls the eye closing movement.

[0036] As a preferred solution, the implantable stimulation electrode is a columnar electrode or a filamentary spiral electrode.

[0037] The present invention discloses a rehabilitation stimulation method and device for recovery of ocular movement disorders, which has the following beneficial effects:

[0038] For patients with facial paralysis, the present invention obtains the corresponding eye movement pattern by identifying the healthy eye, generates a stimulation waveform, and sends it to the stimulation electrode to achieve synchronous eye movement of the affected side and the healthy side. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0040] Figure 1 A flowchart of a rehabilitation stimulation method provided in an embodiment of the present invention.

[0041] Figure 2 A schematic diagram of placing stimulation electrodes on the orbicularis oculi nerve trunk provided in an embodiment of the present invention.

[0042] Figure 3 A schematic diagram of placing stimulation electrodes on the facial nerve trunk provided by an embodiment of the present invention.

[0043] Figure 4 A schematic diagram of a columnar electrode provided in an embodiment of the present invention.

[0044] Figure 5 A schematic diagram of a filamentary spiral electrode provided in an embodiment of the present invention.

[0045] Figure 6 This is a flowchart of step S3 provided in an embodiment of the present invention.

[0046] Figure 7 This is a collection diagram of the side image of the eye provided by an embodiment of the present invention.

[0047] Figure 8 An actual schematic diagram of key points P1-P6 of a side eye image provided by an embodiment of the present invention.

[0048] Fig. 9 A theoretical schematic diagram of key points P1-P6 of a side eye image provided by an embodiment of the present invention.

[0049] Fig.10 A schematic diagram of a head-mounted facial paralysis therapeutic device provided in an embodiment of the present invention. DETAILED DESCRIPTION

[0050] The preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0051] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0052] The expression of “comprising” an element is an “open” expression, which merely means that a corresponding component or step exists, and should not be interpreted as excluding additional components or steps.

[0053] In order to achieve the purpose of the present invention, in some embodiments of the rehabilitation stimulation method and device for recovery of ocular movement disorders, as Figure 1 As shown, rehabilitation stimulation methods include:

[0054] Step S1: collecting eye movement information of the healthy side of the patient in real time;

[0055] Step S2: preprocessing the collected eye movement information of the healthy side of the patient;

[0056] Step S3: analyzing the pre-processed eye movement information of the healthy side of the patient, and predicting whether the eye of the healthy side of the patient is in any movement mode of involuntary blinking, voluntary eye closure, long-term eye closure, or forced eye blinking;

[0057] Step S4: generating a stimulation waveform corresponding to the predicted eye movement pattern of the healthy side of the patient;

[0058] The four modes of involuntary blinking, voluntary eye closure, long-term eye closure, and hard blinking correspond to different waveforms;

[0059] Step S5: Send the stimulation waveform to the signal amplifier, and the signal amplifier generates an excitation current according to the set gain, and the excitation current is transmitted to the stimulation electrode on the affected side of the patient.

[0060] Furthermore, step S1 collects eye movement information of the healthy side in real time by one or more of the following methods;

[0061] Method 1: Using implantable neural electrodes to collect neural electrical signals from the branches of the facial nerve that controls the movement of the orbicularis oculi muscle for eye closing;

[0062] Method 2: Using transcutaneous muscle electrodes to collect the electromyographic signals of the orbicularis oculi muscle that controls the eye closing movement;

[0063] Method 3: Use an image acquisition device to acquire the side image of the eye on the healthy side.

[0064] Furthermore, the preprocessing operation in step S2 includes: filtering, removing artifacts, and setting a baseline for the neural electrical signal or the electromyographic signal; or filtering and de-jittering the side eye image.

[0065] Furthermore, the stimulation electrode on the affected side stimulates the orbicularis oculi muscle and / or nerve that controls the eye closing movement percutaneously or implantably.

[0066] The stimulation current is transmitted to the stimulation electrode on the affected side. For implantable devices, the stimulation current can be fed into the energy using NFC; for transcutaneous methods, it is directly delivered to the muscle and nerve electrodes.

[0067] As shown in Figure 2, the stimulation electrode is placed on the orbicularis oculi nerve trunk; Figure 3 As shown, the stimulating electrode is placed on the trunk of the facial nerve.

[0068] Furthermore, the implantable stimulation electrode may be, but is not limited to, a columnar electrode (e.g. Figure 4 as shown) or a filamentary spiral electrode (as Figure 5 shown).

[0069] Brain-Computer Interface (BCI) is a communication system that does not rely on normal output pathways composed of peripheral nerves and muscles. It refers to a technology that achieves information interaction and functional integration between the nervous system and external devices (such as computers, robots, etc.) by establishing a direct connection pathway between the human brain nerves and external devices.

[0070] In simple terms, it is to realize the control of the machine with the mind. From the perspective of technical implementation, BCI is a cross-disciplinary technology involving neuroscience, signal detection, signal processing, pattern recognition and other disciplines. Brain-computer interaction is the ultimate means of human-computer interaction, which can help disabled people repair visual, auditory and other perceptual functions and motor functions, so that normal people can work and live healthier and more efficiently. For patients with facial nerve damage, more than 90% are unilateral damage, and for patients with facial paralysis, symmetrical facial expressions can meet the needs of daily social interaction, chewing and closing eyes. Therefore, the present invention adopts brain-computer interface technology to realize the synchronous closing of eyes (face) on the affected side and the healthy side. The facial nerve is damaged, generally unilaterally, and for normal people, 90% of the eye-closing movements are bilateral synchronous eye-closing. Through the recognition of the eye-closing movement pattern in the artificial intelligence facial expression, or the collection of the facial nerve electrical signal or the orbicularis oculi muscle electromyographic signal, after processing and analysis, the patient's eye-closing consciousness signal is obtained.

[0071] For the affected side that has lost its motor function due to facial nerve damage, the synchronized movement signals detected by nerve / muscle electrodes are input to achieve normal eye closing function on the affected side.

[0072] Among them, the four modes of involuntary blinking, voluntary eye closure, long eye closure, and hard blinking correspond to different stimulation waveforms to achieve the speed of rapid eyelid closing and opening, the strength of movement, as well as the eyelid closing time and closing strength.

[0073] A specific embodiment is described below, the rehabilitation stimulation method comprises:

[0074] Step S1: using an image acquisition device to acquire a side image of the patient's healthy side of the eye in real time;

[0075] Step S2: pre-processing the collected side eye image of the healthy side of the patient, performing filtering, de-jittering, etc.;

[0076] Step S3: analyzing the pre-processed side image of the patient's healthy side eye, and predicting whether the patient's healthy side eye is in any movement mode of involuntary blinking, voluntary eye closure, long-term eye closure, or forced eye blinking;

[0077] Step S4: generating a stimulation waveform corresponding to the predicted eye movement pattern of the healthy side of the patient;

[0078] Step S5: Send the stimulation waveform to the stimulation electrode on the affected side of the patient.

[0079] like Figure 5-8 As shown, the above step S3 specifically includes:

[0080] Step S3.1: Recognize the side view of the eye in any frame and identify six key points P1, P2, P3, P4, P5, and P6 around the eye;

[0081] Among them: P1 point is the eye corner point;

[0082] Points P3 and P5 are the two farthest points where the eyeball and eyelid meet.

[0083] Point P2 is the point closest to the eyelid around the midpoint of the line L13 connecting points P1 and P3;

[0084] Point P6 is the point closest to the eyelid around the midpoint of the line L15 connecting points P1 and P5;

[0085] Point P4 is the intersection of the upper and lower eyelids with the arc of the outer contour of the eye when the upper and lower eyelids are closed;

[0086] Step S3.2: Calculate the angle a between the line L13 connecting the points P1 and P3 and the line L15 connecting the points P1 and P5;

[0087] Calculate the angle b between the line L12 connecting points P1 and P2 and the line L16 connecting points P1 and P6;

[0088] Step S3.3: determining whether the angle a and the angle b of the eye side image of the frame are qualified;

[0089] If qualified, repeat steps S2 to S4 to calculate the angle a and angle b of the side image of the eye of the next frame. If the angle a and angle b of the side image of the eye of the next frame are qualified, continue to step S3.4;

[0090] If it fails, step S3.4 is not performed;

[0091] Step S3.4: Calculate the angle difference α between the qualified angle a or the qualified angle b corresponding to the side eye images of two adjacent frames;

[0092] If α<0, the eyes are closed at this moment;

[0093] If α>0, the eyes are open at this moment;

[0094] Step S3.5: Repeat steps S3.1 to S3.4 to obtain the angle difference α between the next frame and the eye side image of the previous frame;

[0095] Step S3.6: Calculate Ω by the following formula t , and based on Ω t Determine the speed of eye opening and closing;

[0096] Ω t =(α (t,t+1) -α (t-1,t) ) / △T;

[0097] Where: α (t,t+1) is the angle difference obtained based on the side eye images of two adjacent frames at time t and time t+1;

[0098] α (t-1,t) is the angle difference obtained based on the side eye images of two adjacent frames at time t-1 and time t;

[0099] △T is the sampling time interval between two adjacent frames of eye side images;

[0100] If Ω t >Ω t-1 , it indicates that the eye closing speed is accelerated;

[0101] If Ω t >A, it indicates rapid eye closure;

[0102] If Ω t <A, it indicates slow eye closure, and A is the threshold;

[0103] If Ω t =0, and α (t,t+1) <0, α (t,t+1) <0, it means the eyes are closed;

[0104] If Ω t =0, and α (t,t+1) >0, α (t,t+1) >0, it indicates the eyes are open.

[0105] The angle a and angle b mentioned above are the angles of the upper and lower eyelids.

[0106] P4 is used to check the degree of closure of the upper and lower eyelids, and can be cross-checked with the angles of the upper and lower eyelids.

[0107] Step S3.3 makes a qualified judgment on the angle a and the angle b to ensure accurate calculation and avoid misjudgment.

[0108] Step S3.4 makes a judgment based on the angle change of the upper and lower eyelids between the previous and next two frames (angle difference α).

[0109] Specifically, α t-1 =a t -a t-1 , or, α t-1 =b t -b t-1 ;

[0110] a t 、b t is the angle of the side image of the eye at time t;

[0111] a t-1 、b t-1 is the angle of the side eye image in the frame at time t-1.

[0112] In the above step S3.1, a neural convolutional network or an image recognition algorithm is used to recognize the side eye image of any frame.

[0113] Further, step S3.3 is specifically to use the angle difference δ to determine whether the angle a and the angle b of the side eye image of the frame are qualified, and the angle difference δ is the difference between the angle a and the angle b;

[0114] If the angle difference δ does not exceed the threshold value (e.g., 5°), the image is qualified, and steps S3.1 to S3.3 are repeated to calculate the angle a and angle b of the eye side image of the next frame. If the angle a and angle b of the eye side image of the next frame are qualified, step S3.4 is continued;

[0115] If the angle difference δ exceeds the threshold, it is unqualified and step S3.4 is not executed. The image acquisition device (such as the lens) can be further checked to see if it is seriously contaminated and a repair report can be submitted.

[0116] In a specific embodiment, the threshold value (eg, 5°) should be set according to different groups of people, such as skin color and skin aging degree, to avoid invalid misjudgment.

[0117] Further, in step S3.3, if the angle a and the angle b are unqualified, the steps S3.1 to S3.3 are executed again in sequence to calculate the angle a and the angle b of the next frame of the side eye image and determine whether they are qualified;

[0118] If the angle difference δ exceeds the threshold value repeatedly, an alarm is triggered.

[0119] The present invention analyzes and identifies the side image of the eye, and identifies the eye movement state based on the angle recognition method. Compared with the traditional method of collecting the frontal image of the eye, the present invention can install the image acquisition device (such as a camera) on the side of the eye to reduce the impact on the human body.

[0120] For existing head-mounted facial paralysis therapeutic devices (such as Fig.10 The glasses-like structure shown in the figure) can install image acquisition devices (such as cameras) on both sides of the therapeutic device (specifically, they can be installed at the temples), which further improves the aesthetics and reduces the pressure on the user's eyes.

[0121] The embodiment of the present invention further discloses a rehabilitation stimulation device for recovery of ocular movement disorders, comprising:

[0122] Eye movement information collection module, used to collect eye movement information of the healthy side of the patient in real time;

[0123] A preprocessing module, used for preprocessing the collected eye movement information of the healthy side of the patient;

[0124] An analysis and processing module is used to analyze the pre-processed eye movement information of the healthy side of the patient, and predict whether the eye of the healthy side of the patient is in any movement mode of involuntary blinking, voluntary eye closure, long-term eye closure, or forced eye blinking;

[0125] A stimulation waveform generation module, used for generating a stimulation waveform corresponding to the pattern according to the predicted eye movement pattern of the healthy side of the patient;

[0126] The stimulation waveform sending module is used to send the stimulation waveform to the stimulation electrode on the affected side of the patient.

[0127] Furthermore, the eye movement information collection module collects the eye movement information of the healthy side in real time by one or more of the following methods;

[0128] Method 1: Using implantable neural electrodes to collect neural electrical signals from the branches of the facial nerve that controls the movement of the orbicularis oculi muscle for eye closing;

[0129] Method 2: Using transcutaneous muscle electrodes to collect the electromyographic signals of the orbicularis oculi muscle that controls the eye closing movement;

[0130] Method 3: Use an image acquisition device to acquire the side image of the eye on the healthy side.

[0131] Furthermore, the preprocessing operations in the preprocessing module include: filtering, removing artifacts, and setting a baseline for neural electrical signals or electromyographic signals; or filtering and de-jittering the side eye image.

[0132] Furthermore, the stimulation electrode on the affected side stimulates the orbicularis oculi muscle and / or nerve that controls the eye closing movement percutaneously or implantably.

[0133] Furthermore, the implantable stimulation electrode is a columnar electrode or a filamentary spiral electrode.

[0134] In this embodiment, the specific content of the rehabilitation stimulation device for recovery of ocular movement disorders is similar to the content of the rehabilitation stimulation method for recovery of ocular movement disorders disclosed in the above embodiments, and will not be repeated here.

[0135] The present invention discloses a rehabilitation stimulation method and device for recovery of ocular movement disorders, which has the following beneficial effects:

[0136] For patients with facial paralysis, the present invention obtains the corresponding eye movement pattern by identifying the healthy eye, generates a stimulation waveform, and sends it to the stimulation electrode to achieve synchronous eye movement of the affected side and the healthy side.

[0137] It should be understood that the various techniques described herein can be implemented in combination with hardware or software, or a combination thereof. Thus, the method and apparatus of the present invention, or some aspects or portions of the method and apparatus of the present invention, can take the form of program codes (i.e., instructions) embedded in a tangible medium, such as a floppy disk, a CD-ROM, a hard disk drive, or any other machine-readable storage medium, wherein when the program is loaded into a machine such as a computer and executed by the machine, the machine becomes a device for practicing the present invention.

[0138] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for illustrating the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which shall fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A rehabilitation stimulation method for recovery of ocular movement disorders, characterized in that: include: Step S1: collecting eye movement information of the healthy side of the patient in real time; Step S2: preprocessing the collected eye movement information of the healthy side of the patient; Step S3: analyzing the pre-processed eye movement information of the healthy side of the patient, and predicting whether the eye of the healthy side of the patient is in any movement mode of involuntary blinking, voluntary eye closure, long-term eye closure, or forced eye blinking; Step S4: generating a stimulation waveform corresponding to the predicted eye movement pattern of the healthy side of the patient; Step S5: Send the stimulation waveform to the stimulation electrode on the affected side of the patient.

2. The rehabilitation stimulation method according to claim 1, characterized in that: The step S1 collects eye movement information of the healthy side in real time by one or more of the following methods; Method 1: Using implantable neural electrodes to collect neural electrical signals from the branches of the facial nerve that controls the movement of the orbicularis oculi muscle for eye closing; Method 2: Using transcutaneous muscle electrodes to collect the electromyographic signals of the orbicularis oculi muscle that controls the eye closing movement; Method 3: Use an image acquisition device to acquire the side image of the eye on the healthy side.

3. The rehabilitation stimulation method according to claim 2, characterized in that: The preprocessing operation in step S2 includes: filtering, removing artifacts, and setting a baseline for the neural electrical signal or the electromyographic signal; or filtering and removing jitter for the side image of the eye.

4. The rehabilitation stimulation method according to claim 1, characterized in that: The stimulation electrode on the affected side stimulates the orbicularis oculi muscle and / or nerve that controls the eye closing movement through the skin or implantation.

5. The rehabilitation stimulation method according to claim 4, characterized in that: The implantable stimulation electrode is a columnar electrode or a filamentary spiral electrode.

6. A rehabilitation stimulation device for recovery from ocular movement disorders, characterized in that: include: Eye movement information collection module, used to collect eye movement information of the healthy side of the patient in real time; A preprocessing module, used for preprocessing the collected eye movement information of the healthy side of the patient; An analysis and processing module is used to analyze the pre-processed eye movement information of the healthy side of the patient, and predict whether the eye of the healthy side of the patient is in any movement mode of involuntary blinking, voluntary eye closure, long-term eye closure, or forced eye blinking; A stimulation waveform generation module, used for generating a stimulation waveform corresponding to the pattern according to the predicted eye movement pattern of the healthy side of the patient; The stimulation waveform sending module is used to send the stimulation waveform to the stimulation electrode on the affected side of the patient.

7. The rehabilitation stimulation device according to claim 6, characterized in that The eye movement information acquisition module acquires the eye movement information of the healthy side in real time by one or more of the following methods; Method 1: Using implantable neural electrodes to collect neural electrical signals from the branches of the facial nerve that controls the movement of the orbicularis oculi muscle for eye closing; Method 2: Using transcutaneous muscle electrodes to collect the electromyographic signals of the orbicularis oculi muscle that controls the eye closing movement; Method 3: Use an image acquisition device to acquire the side image of the eye on the healthy side.

8. The rehabilitation stimulation device according to claim 7, characterized in that: The preprocessing operations in the preprocessing module include: filtering, removing artifacts, and setting a baseline for neural electrical signals or electromyographic signals; or filtering and removing jitter for side eye images.

9. The rehabilitation stimulation device according to claim 6, characterized in that: The stimulation electrode on the affected side stimulates the orbicularis oculi muscle and / or nerve that controls the eye closing movement through the skin or implantation.

10. The rehabilitation stimulation device according to claim 9, characterized in that The implantable stimulation electrode is a columnar electrode or a filamentary spiral electrode.

Images