Energy-saving grinding device before ganciclovir crude product impurity removal
By designing a multi-stage progressive grinding device and a linkage mechanism, the problems of high energy consumption and long grinding time of crude ganciclovir were solved, achieving a highly efficient grinding effect.
Patent Information
- Application Number
- CN202411797878.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-09
- Publication Date
- 2025-11-28
- Estimated Expiration
- 2044-12-09
AI Technical Summary
The grinding process of crude ganciclovir is energy-intensive and time-consuming, and traditional equipment is inefficient.
A multi-stage progressive grinding device is adopted, which uses grinding cylinders with decreasing diameters and inclined grinding teeth in conjunction with grinding rollers. The grinding and discharge of materials are controlled by the forward and reverse rotation of the motor and the linkage mechanism to achieve multiple cycles of grinding.
It significantly improves grinding efficiency, shortens the grinding cycle, reduces energy consumption, and enhances grinding results.
Smart Images
Figure CN119425852B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of ganciclovir grinding, in particular to a ganciclovir crude product impurity removal pre-energy saving grinding device. BACKGROUND
[0002] Ganciclovir is an important antiviral drug and has a wide application in the medical field. The crude product is usually obtained in the chemical synthesis process, contains many impurities and the particle state is often uneven, which cannot be directly used for the subsequent key links of pharmaceutical.
[0003] In the production process of ganciclovir, grinding the ganciclovir crude product is a key step, which aims to reduce the particle size and increase the specific surface area, so as to facilitate the subsequent impurity removal, refining and other processes. The traditional grinding method mainly relies on ball mill, vibration mill and other equipment. The ball mill drives the grinding ball to impact and rub the crude product through the rotation of the grinding tank. Although a certain degree of grinding effect can be achieved, there are problems of high energy consumption and long grinding time. SUMMARY
[0004] The purpose of the present application is to provide a ganciclovir crude product impurity removal pre-energy saving grinding device, which solves the problem of high energy consumption and long time in the background art.
[0005] In order to achieve the above object, the present application provides the following technical scheme: the ganciclovir crude product energy-saving grinding device before impurity removal, including the shell and the inner cylinder arranged in the shell, further including the grinding roller arranged in the inner cylinder, the inner cylinder includes the third grinding cylinder, the second grinding cylinder, the first grinding cylinder and the collecting disc connected in turn from top to bottom, and the diameters of the first grinding cylinder, the second grinding cylinder and the third grinding cylinder decrease in turn upwards, the grinding roller includes the first grinding disc, the second grinding disc and the third grinding disc rotatingly connected in the first grinding cylinder, the second grinding cylinder and the third grinding cylinder respectively, and the first grinding disc, the second grinding disc and the third grinding disc are fixedly connected, the outer edges of the first grinding disc, the second grinding disc and the third grinding disc are uniformly distributed with the grinding teeth, and the grinding teeth are arranged in an inclined manner, one side of the grinding teeth is smoothly connected with the outer wall of the first grinding disc, the second grinding disc and the third grinding disc, and the other side of the grinding teeth is provided with a slope on the outer wall of the first grinding disc, the second grinding disc and the third grinding disc, and the gap for grinding is formed between the first grinding disc, the second grinding disc and the third grinding disc and the inner wall of the first grinding cylinder, the second grinding cylinder and the third grinding cylinder, the gap between the third grinding disc and the third grinding cylinder is greater than the gap between the second grinding disc and the second grinding cylinder, and the gap between the first grinding disc and the first grinding cylinder is the smallest, the inside of the shell below the grinding roller is provided with a motor, the motor is used for driving the forward and reverse rotation of the grinding roller, the outside of the grinding roller in the inside of the shell is provided with a linkage mechanism, the above of the grinding roller in the inside of the shell is provided with a discharging control mechanism and a positioning disc, wherein the linkage mechanism and the discharging control mechanism are used for controlling the material to be ground in turn from top to bottom, and the positioning disc is used for positioning the discharging control mechanism.
[0006] Further, the bottom of the third grinding cylinder is fixedly connected with a second blocking ring, a gap is arranged between the second blocking ring and the second grinding cylinder, the outer side of the second blocking ring is fixedly connected with the second grinding cylinder through a fixing piece, the bottom of the second grinding cylinder is fixedly connected with a first blocking ring, a gap is arranged between the first blocking ring and the first grinding cylinder, and the outer side of the first blocking ring is fixedly connected with the first grinding cylinder through a fixing piece.
[0007] Further, the inside of the collecting disc is provided with an inclined collecting groove, the outside of the collecting disc is provided with a discharging pipe, one end of the discharging pipe is communicated with the collecting groove, the other end of the discharging pipe extends to the outside of the shell, the top of the third grinding cylinder is further provided with a distributing disc, a gap is arranged between the distributing disc and the third grinding cylinder, the distributing disc is fixedly connected with the third grinding cylinder through a fixing piece, and the distributing disc is not fixed with the third grinding disc.
[0008] Further, the motor output end is fixedly connected with a driving rod, the top of the driving rod is fixedly connected with the middle of the bottom of the first grinding disc, the outside of the driving rod is provided with external threads, and the external threads are outwardly protruding thread-shaped; the linkage mechanism comprises a movable frame, the movable frame is L-shaped, the movable frame is provided with two groups, the connecting part of the two groups of movable frames is provided with a threaded seat, the threaded seat is installed on the outside of the driving rod, and the threaded seat corresponds to the driving rod, a compression spring is installed between the bottom of the movable frame and the inner wall of the bottom of the shell, and the top inner side of the movable frame is fixedly installed with a connecting frame.
[0009] Further, the discharging control mechanism comprises a first blocking ring, a second blocking ring and a third blocking ring arranged from the outside to the inside, wherein the bottoms of the first blocking ring, the second blocking ring and the third blocking ring are respectively the tops of the first grinding cylinder, the second grinding cylinder and the third grinding cylinder, the connecting frame is fixedly connected with the first blocking ring, the second blocking ring and the third blocking ring through a sliding block, the first blocking ring, the second blocking ring and the third blocking ring are slidingly connected below the inside of the positioning disc, the top of the positioning disc is provided with a feeding pipe extending to the outside of the shell, and the middle of the positioning disc is provided with a slot penetrating up and down.
[0010] Further, the discharging control mechanism further comprises a first material blocking ring and a second material blocking ring slidingly connected below the positioning disc, wherein the first material blocking ring and the second material blocking ring are respectively located on the inner side of the first blocking ring and the second blocking ring and correspond to the outer wall of the first blocking ring and the second blocking ring.
[0011] Further, the first blocking ring and the first material blocking ring and the second blocking ring and the second material blocking ring are provided with transmission mechanisms.
[0012] Further, the transmission mechanism comprises a second tooth groove arranged on the inner wall of the first blocking ring and the second blocking ring, and a first tooth groove arranged on the outer wall of the first material blocking ring and the second material blocking ring, and further comprises a straight gear installed below the positioning disc through a mounting frame, and the straight gear is meshingly connected between the second tooth groove and the first tooth groove.
[0013] Compared with the prior art, the beneficial effects of the present application are:
[0014] The energy-saving grinding device for removing impurities from crude ganciclovir provided by the present application comprises a third grinding cylinder, a second grinding cylinder, a first grinding cylinder and a collecting disc with decreasing diameters, which are matched with a grinding roller fixedly connected and provided with inclined grinding teeth on the outer edge to form a multi-layer progressive grinding space, the inclined grinding teeth generate a downward extrusion force, the material crushing is more efficient, the grinding degree can be accurately controlled, the material is ground from coarse grinding to fine grinding, the grinding roller is driven by the motor to rotate in the forward and reverse directions, the motor is rotated counterclockwise to grind, and clockwise rotation realizes material transfer and circulation, which greatly improves the overall grinding efficiency, effectively shortens the grinding period, and improves the efficiency compared with traditional grinding equipment. BRIEF DESCRIPTION OF DRAWINGS
[0015] Figure 1 The overall structure of the present application is shown in the figure;
[0016] Figure 2 The overall structure of the present application is shown in the figure;
[0017] Figure 3 The structure of the inner cylinder, grinding roller, motor and positioning disc of the present application is shown in the figure;
[0018] Figure 4 The structure of the inner cylinder, grinding roller, motor, linkage mechanism, discharge control mechanism and positioning disc of the present application is shown in the figure;
[0019] Figure 5 The structure of the inner cylinder, grinding roller and motor of the present application is shown in the figure;
[0020] Figure 6 The structure of the inner cylinder and grinding roller of the present application is shown in the figure;
[0021] Figure 7 The structure of the linkage mechanism and discharge control mechanism of the present application is shown in the figure;
[0022] Figure 8 The structure of the linkage mechanism, discharge control mechanism and positioning disc of the present application is shown in the figure.
[0023] In the figure: 1, outer shell; 2, inner cylinder; 21, first grinding cylinder; 22, second grinding cylinder; 221, first blocking ring; 23, third grinding cylinder; 231, second blocking ring; 24, collecting disc; 241, collecting groove; 242, discharge pipe; 3, grinding roller; 31, first grinding disc; 32, second grinding disc; 33, third grinding disc; 34, grinding teeth; 35, distribution disc; 4, motor; 41, driving rod; 42, external thread; 5, linkage mechanism; 51, movable frame; 52, threaded seat; 53, compression spring; 54, connecting frame; 55, sliding block; 6, discharge control mechanism; 61, first blocking ring; 62, second blocking ring; 63, third blocking ring; 64, first material blocking ring; 65, second material blocking ring; 66, transmission mechanism; 661, first gear slot; 662, second gear slot; 663, spur gear; 7, positioning disc; 71, feeding pipe. DETAILED DESCRIPTION
[0024] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.
[0025] In order to solve the technical problem of high energy consumption and long time in grinding of ganciclovir crude product, the following preferred technical solutions are provided, as shown in Figures 1-8
[0026] As shown in Figures 1-3 The energy-saving grinding device for removing impurities before ganciclovir crude product includes a shell 1 and an inner cylinder 2 arranged inside the shell 1, and further includes a grinding roller 3 arranged inside the inner cylinder 2, as shown in Figures 4-5 The inner cylinder 2 includes a third grinding cylinder 23, a second grinding cylinder 22, a first grinding cylinder 21 and a collecting disc 24 connected in sequence from top to bottom, and the diameters of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23 decrease in sequence from top to bottom. The grinding roller 3 includes a first grinding disc 31, a second grinding disc 32 and a third grinding disc 33 rotatably connected inside the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23, respectively, and the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33 are fixedly connected. The outer edges of the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33 are uniformly distributed with grinding teeth 34, and the grinding teeth 34 are inclinedly arranged. One side of the grinding teeth 34 is smoothly transitioned with the outer walls of the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33, and the other side of the grinding teeth 34 is provided with a slope with the outer walls of the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33. The first grinding disc 31, the second grinding disc 32 and the third grinding disc 33 and the inner walls of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23 form a gap for grinding, as shown in Figure 6 As shown, the gap between the third grinding disc 33 and the third grinding cylinder 23 is larger than the gap between the second grinding disc 32 and the second grinding cylinder 22, which is larger than the gap between the first grinding disc 31 and the first grinding cylinder 21. A motor 4 is arranged below the grinding roller 3 inside the shell 1 and is used to drive the grinding roller 3 to rotate forward and reverse. A linkage mechanism 5 is arranged outside the grinding roller 3 inside the shell 1. A discharge control mechanism 6 and a positioning disc 7 are arranged above the grinding roller 3 inside the shell 1. The linkage mechanism 5 and the discharge control mechanism 6 are used to control the material to be ground from top to bottom in sequence. The positioning disc 7 is used to position the discharge control mechanism 6. When the motor 4 drives the grinding roller 3 to rotate counterclockwise, the grinding teeth 34 outside the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33 continuously extrude the material, so that the material is ground and crushed. Since the grinding teeth 34 are inclined, the material is extruded obliquely downward under the action of rotation, which is more conducive to crushing. When the motor 4 drives the grinding roller 3 to rotate clockwise, the slope between the grinding teeth 34 and the outer wall of the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33, as well as the inclined grinding teeth 34, will move the material upward, so that the material in the third grinding cylinder 23 falls into the second grinding cylinder 22, the material in the second grinding cylinder 22 falls into the first grinding cylinder 21, and the material in the first grinding cylinder 21 falls into the collection groove 241 and finally flows out of the discharge pipe 242.
[0027] As shown in Figure 5 , the bottom of the third grinding cylinder 23 is fixedly connected with a second blocking ring 231. A gap is arranged between the second blocking ring 231 and the second grinding cylinder 22. The outer side of the second blocking ring 231 is fixedly connected with the second grinding cylinder 22 through a fixing member. The bottom of the second grinding cylinder 22 is fixedly connected with a first blocking ring 221. A gap is arranged between the first blocking ring 221 and the first grinding cylinder 21. The outer side of the first blocking ring 221 is fixedly connected with the first grinding cylinder 21 through a fixing member. The bottom of the first grinding cylinder 21 is fixedly connected with the collection disc 24.
[0028] The inside of the collection disc 24 is provided with an inclined collection groove 241. The outside of the collection disc 24 is provided with a discharge pipe 242. One end of the discharge pipe 242 communicates with the collection groove 241. The other end of the discharge pipe 242 extends to the outside of the shell 1. The top of the third grinding cylinder 23 is further provided with a distribution disc 35. A gap is arranged between the distribution disc 35 and the third grinding cylinder 23. The distribution disc 35 is fixedly connected with the third grinding cylinder 23 through a fixing member. The distribution disc 35 is not fixed with the third grinding disc 33.
[0029] As shown in Figure 5 , the output end of the motor 4 is fixedly connected with a driving rod 41. The top of the driving rod 41 is fixedly connected with the middle of the bottom of the first grinding disc 31. The outside of the driving rod 41 is provided with external threads 42, which are outwardly protruding threads.
[0030] As Figure 7 shown, the linkage mechanism 5 includes a movable frame 51, the movable frame 51 is L-shaped, the movable frame 51 is provided with two groups, the connecting part of the two groups of movable frames 51 is provided with a threaded seat 52, the threaded seat 52 is installed outside the driving rod 41, and the threaded seat 52 corresponds to the driving rod 41, a compression spring 53 is installed between the bottom of the movable frame 51 and the inner wall of the bottom of the shell 1, and the top inner side of the movable frame 51 is fixedly installed with a connecting frame 54, when the threaded seat 52 is above the external thread 42, under the action of the self weight of the linkage mechanism 5, the driving rod 41 rotates counterclockwise, the threaded seat 52 descends, until the threaded seat 52 is disengaged from the external thread 42, the threaded seat 52 can slide outside the driving rod 41, the driving rod 41 rotates clockwise, the threaded seat 52 is engaged with the external thread 42 under the action of the compression spring 53, and the threaded seat 52 rises.
[0031] As Figures 7-8 shown, the discharge control mechanism 6 includes a first blocking ring 61, a second blocking ring 62 and a third blocking ring 63 arranged from outside to inside, wherein the bottoms of the first blocking ring 61, the second blocking ring 62 and the third blocking ring 63 are respectively the tops of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23, the connecting frame 54 is fixedly connected with the first blocking ring 61, the second blocking ring 62 and the third blocking ring 63 through the sliding block 55, the first blocking ring 61, the second blocking ring 62 and the third blocking ring 63 are slidingly connected below the inside of the positioning disc 7, the top of the positioning disc 7 is provided with a feeding pipe 71 extending to the outside of the shell 1, and the middle part of the positioning disc 7 is provided with a slot penetrating up and down.
[0032] The discharge control mechanism 6 further includes a first material blocking ring 64 and a second material blocking ring 65 slidingly connected below the positioning disc 7, wherein the first material blocking ring 64 and the second material blocking ring 65 are respectively located on the inner sides of the first blocking ring 61 and the second blocking ring 62, and correspond to the outer walls of the first blocking ring 221 and the second blocking ring 231.
[0033] The transmission mechanism 66 is arranged on the inner wall of the first blocking ring 61 and the second blocking ring 62, and on the outer wall of the first material blocking ring 64 and the second material blocking ring 65. When the motor 4 drives the driving rod 41 to rotate counterclockwise, the movable frame 51 is lowered under the meshing action of the threaded seat 52 and the external thread 42, and drives the first blocking ring 61, the second blocking ring 62 and the third blocking ring 63 to be lowered through the connecting frame 54 and the sliding block 55, and the first material blocking ring 64 and the second material blocking ring 65 are raised. At this time, the materials in the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23 are ground under the counterclockwise rotation of the grinding roller 3. When the materials are well ground, the motor 4 drives the driving rod 41 to rotate clockwise, the movable frame 51 is raised, the first blocking ring 61, the second blocking ring 62 and the third blocking ring 63 are raised, and the first material blocking ring 64 and the second material blocking ring 65 are lowered. The materials overflow from the top of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23. The materials overflowing from the inside of the first grinding cylinder 21 are left between the outer wall of the first grinding cylinder 21 and the inner wall of the second material blocking ring 65. The materials overflowing from the inside of the second grinding cylinder 22 are left between the outer wall of the second grinding cylinder 22 and the inner wall of the first material blocking ring 64. The materials overflowing from the inside of the third grinding cylinder 23 enter the collecting groove 241 and are discharged from the discharge pipe 242. When the motor 4 is switched to counterclockwise rotation, the first blocking ring 61, the second blocking ring 62 and the third blocking ring 63 are lowered, the first material blocking ring 64 and the second material blocking ring 65 are raised, the materials ground by the first grinding cylinder 21 enter the second grinding cylinder 22, and the materials ground by the second grinding cylinder 22 enter the third grinding cylinder 23.
[0034] The transmission mechanism 66 includes a second tooth groove 662 arranged on the inner wall of the first blocking ring 61 and the second blocking ring 62, and a first tooth groove 661 arranged on the outer wall of the first material blocking ring 64 and the second material blocking ring 65. The transmission mechanism 66 also includes a straight gear 663 installed below the positioning disc 7 through a mounting frame. The straight gear 663 is engaged between the second tooth groove 662 and the first tooth groove 661. That is, when the first blocking ring 61 and the second blocking ring 62 are lowered, the second tooth groove 662 engages the straight gear 663 to engage the first tooth groove 661 to drive the first material blocking ring 64 and the second material blocking ring 65 to rise. When the first blocking ring 61 and the second blocking ring 62 are raised, the second tooth groove 662 engages the straight gear 663 to engage the first tooth groove 661 to drive the first material blocking ring 64 and the second material blocking ring 65 to be lowered.
[0035] The materials enter the device through the feeding pipe 71 and fall on the distributing disc 35 to be dispersed. At this time, the first blocking ring 61, the second blocking ring 62 and the third blocking ring 63 are in the initial lower position, and the first material blocking ring 64 and the second material blocking ring 65 are in the initial upper position. The materials can first enter the third grinding cylinder 23 for grinding.
[0036] The motor 4 drives the grinding roller 3 to rotate counterclockwise, and the grinding teeth 34 continuously crush the material in the third grinding cylinder 23 by virtue of the oblique design and the oblique downward extrusion force generated by rotation. When the material is ground to the standard, the motor 4 rotates clockwise, the threaded seat 52 is engaged with the outer thread 42 of the driving rod 41 and rises under the action of the compression spring 53, and the first stop ring 61, the second stop ring 62 and the third stop ring 63 are lifted to the upper position through the linkage mechanism 5, while the first material stop ring 64 and the second material stop ring 65 are lowered to the lower position through the transmission mechanism 66, so as to make the material in the third grinding cylinder 23 overflow to the space between the third stop ring 63 and the third grinding cylinder 23;
[0037] The motor 4 rotates counterclockwise again, the first stop ring 61, the second stop ring 62 and the third stop ring 63 are lowered, the first material stop ring 64 and the second material stop ring 65 are raised, and the material enters the second grinding cylinder 22 for grinding. During this period, new material can enter the third grinding cylinder 23. Subsequent control of the motor 4 is performed to make the material in the second grinding cylinder 22 enter the first grinding cylinder 21 for grinding, and finally the material is discharged from the discharge pipe 242 of the first grinding cylinder 21, so as to realize three-time grinding in a cycle and achieve continuous operation with feeding and discharging at the same time.
[0038] It should be noted that the relational terms herein such as first and second and the like are used only to differentiate one entity or action from another, and do not necessarily require or imply that any such actual relationship or order exists between or among the entities or actions. Also, the terms "comprising", "including", or any other variant thereof are intended to cover a non-exclusive inclusion, so that a process, method, article or apparatus that comprises a list of elements does not include only those elements but can also include other elements not expressly listed or inherent to such process, method, article or apparatus.
[0039] The above description is only the preferred embodiment of the present application, and the protection scope of the present application is not limited thereto. Any person skilled in the art can make equivalent replacements or changes to the technical scheme and the inventive concept of the present application within the technical scope disclosed by the present application, and such replacements or changes should be covered within the protection scope of the present application.
Claims
1. An energy-saving grinding device for crude ganciclovir before impurity removal, comprising a housing (1) and an inner cylinder (2) disposed inside the housing (1), and further comprising a grinding roller (3) disposed inside the inner cylinder (2), characterized in that: The inner cylinder (2) comprises a third grinding cylinder (23), a second grinding cylinder (22), a first grinding cylinder (21) and a collecting disc (24) connected in sequence from top to bottom, and the diameters of the first grinding cylinder (21), the second grinding cylinder (22) and the third grinding cylinder (23) decrease in sequence from top to bottom; the grinding roller (3) comprises a first grinding disc (31), a second grinding disc (32) and a third grinding disc (33) rotatingly connected inside the first grinding cylinder (21), the second grinding cylinder (22) and the third grinding cylinder (23) respectively, and the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33) are fixedly connected; the outer edges of the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33) are uniformly provided with grinding teeth (34), and the grinding teeth (34) are arranged in an inclined manner; one side of the grinding tooth (34) is smoothly connected with the outer wall of the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33); the other side of the grinding tooth (34) is provided with a slope with respect to the outer wall of the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33); the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33) and the inner walls of the first grinding cylinder (21), the second grinding cylinder (22) and the third grinding cylinder (23) form gaps for grinding; the gap between the third grinding disc (33) and the third grinding cylinder (23) is greater than the gap between the second grinding disc (32) and the second grinding cylinder (22), which is greater than the gap between the first grinding disc (31) and the first grinding cylinder (21); the motor (4) is arranged below the grinding roller (3) in the housing (1) and used to drive the grinding roller (3) to rotate in the forward direction and the reverse direction; the linkage mechanism (5) is arranged outside the grinding roller (3) in the housing (1); the discharging control mechanism (6) and the positioning disc (7) are arranged above the grinding roller (3) in the housing (1); the linkage mechanism (5) and the discharging control mechanism (6) are used to control the material to be ground in sequence from top to bottom; and the positioning disc (7) is used to position the discharging control mechanism (6); The bottom of the third grinding cylinder (23) is fixedly connected with a second blocking ring (231), a gap is arranged between the second blocking ring (231) and the second grinding cylinder (22), the outer side of the second blocking ring (231) is fixedly connected with the second grinding cylinder (22) through a fixing member; the bottom of the second grinding cylinder (22) is fixedly connected with a first blocking ring (221), a gap is arranged between the first blocking ring (221) and the first grinding cylinder (21), and the outer side of the first blocking ring (221) is fixedly connected with the first grinding cylinder (21) through a fixing member; and the bottom of the first grinding cylinder (21) is fixedly connected with the collecting disc (24); The output end of the motor (4) is fixedly connected with a driving rod (41), the top of the driving rod (41) is fixedly connected with the middle of the bottom of the first grinding disc (31), and the outer part of the driving rod (41) is provided with external threads (42) in the form of outwardly protruding threads. The linkage mechanism (5) comprises movable racks (51), the movable racks (51) are L-shaped, two groups of movable racks (51) are arranged, threaded seats (52) are arranged at the connection positions of the two groups of movable racks (51), the threaded seats (52) are arranged outside the driving rods (41) and correspond to the driving rods (41), compression springs (53) are arranged between the bottoms of the movable racks (51) and the inner walls of the bottoms of the housings (1). The discharge control mechanism (6) comprises first, second and third blocking rings (61, 62 and 63) arranged from outside to inside, wherein the bottoms of the first, second and third blocking rings (61, 62 and 63) are respectively connected to the tops of the first, second and third grinding cylinders (21, 22 and 23), the connecting racks (54) are fixedly connected to the first, second and third blocking rings (61, 62 and 63) through sliding blocks (55), the first, second and third blocking rings (61, 62 and 63) are slidingly connected to the inner bottom of the positioning disc (7), the top of the positioning disc (7) is provided with a feeding pipe (71) extending to the outside of the housing (1), the middle of the positioning disc (7) is provided with a slot extending from top to bottom, the first and second material blocking rings (64 and 65) are slidingly connected to the lower part of the positioning disc (7), wherein the first and second material blocking rings (64 and 65) are respectively arranged on the inner sides of the first and second blocking rings (61 and 62) and correspond to the outer walls of the first and second blocking rings (221 and 231), and transmission mechanisms (66) are arranged between the first blocking ring (61) and the first material blocking ring (64) and between the second blocking ring (62) and the second material blocking ring (65). The transmission mechanism (66) comprises second tooth grooves (662) arranged in the inner walls of the first and second blocking rings (61 and 62) and first tooth grooves (661) arranged in the outer walls of the first and second material blocking rings (64 and 65), and a straight gear (663) installed below the positioning disc (7) through a mounting rack, the straight gear (663) is meshingly connected between the second tooth grooves (662) and the first tooth grooves (661).
2. The pre-purification energy-saving grinding device for ganciclovir crude product according to claim 1, characterized in that: The inside of the collecting disc (24) is provided with an inclined collecting groove (241), the outside of the collecting disc (24) is provided with a discharge pipe (242), one end of the discharge pipe (242) is communicated with the collecting groove (241), and the other end of the discharge pipe (242) extends to the outside of the housing (1).
3. The pre-grinding device for removing impurities from crude ganciclovir according to claim 1, characterized in that: The top of the third grinding cylinder (23) is further provided with a distribution disc (35), a gap is arranged between the distribution disc (35) and the third grinding cylinder (23), the distribution disc (35) is fixedly connected to the third grinding cylinder (23) through a fixing member, and the distribution disc (35) is not fixed to the third grinding disc (33).
Citation Information
Patent Citations
Raw material grinding equipment in field of food processing machinery
CN211801116U
Efficient energy-saving grinding machine
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