Vertical beam boron neutron capture therapy system and neutron target system

Abstract

The invention relates to the technical field of boron neutron capture therapy application based on accelerator driving, in particular to boron neutron capture therapy equipment which adopts linear accelerator equipment to accelerate particles such as protons to bombard a target body so as to generate neutrons, and particularly relates to a vertical beam boron neutron capture therapy system and a neutron target system. The neutron target system comprises a target body container, a rotating target and an evaporation slowing-down assembly, an incidence cavity, a target body cavity and an equipment cavity which are communicated with one another are formed in the target body container, an incidence opening communicated with the incidence cavity is formed in the top end of the target body container, the rotating target comprises a target body and a transmission shaft, and the evaporation slowing-down assembly comprises a slowing-down body, a connecting piece and an evaporation device. According to the invention, the integration of the steps of target material installation, moderation, evaporation, cleaning, drying, operation and the like can be completed, the manufacturing, the operation, the maintenance and the like of the target body are integrated in the same container, the target body is prevented from being frequently disassembled and replaced, and the related cost is reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of accelerator-driven boron neutron capture therapy applications, specifically to a boron neutron capture therapy device that uses a linear accelerator device to accelerate protons and other particles to bombard a target body to generate neutrons, and more particularly to a vertical beam boron neutron capture therapy system and a neutron target system. Background Art

[0002] Boron Neutron Capture Therapy (BNCT) refers to a binary targeted intracellular radiotherapy technology that uses the fission products of thermal neutrons captured by the B-10 element to kill tumor cells. It has precise targeting at the cellular level. This is because the boron-containing drugs pre-injected into the human body are targeted, and the affinity between the drugs and cancer cells is used to enrich the drugs in cancer cells, while the distribution in normal tissues is relatively small. When neutrons are used for external irradiation of the tumor site, the B-10 element in the drug captures neutrons and undergoes fission reactions, releasing high-energy alpha particles and lithium ions with high linear energy transfer (LET). These two particles have strong lethality to cancer cells and both have high energy transfer line density. At the same time, they have a strong relative biological effect on cancer cells. The energy generated by only a few alpha particles can produce a lethal effect on tumor cells, and cause less damage to normal tissues.

[0003] When particles or rays generated by the accelerator bombard the neutron generating target, especially after the incidence of low-energy protons, high-energy deposition will be formed at the front end of the target. For example, in the boron neutron capture therapy for cancer, the proton energy used is between 2MeV and 10MeV, the proton beam power is as high as 30kW or more, and the heat flux density exceeds 100kW / cm2, so the heat dissipation problem of the target needs to be solved urgently. The neutron performance of lithium targets is better than that of beryllium targets. It has a higher neutron yield at a lower proton beam energy of 2.5 to 3.5MeV, and the neutron energy is also low and easy to slow down.

[0004] Chinese patent application number CN218925979U discloses a device for producing a rotating lithium target material. Although it can continuously produce lithium material, there is no vacuum protection on the outside, and the newly formed lithium layer is quickly oxidized, resulting in an unsatisfactory final effect. Chinese patent application number CN113260131A discloses a solid lithium target chamber with a sealing structure, which can maintain a vacuum environment during the transportation, installation, and maintenance of the lithium target. However, lithium material consumption will occur during the target shooting process, so the target body needs to be taken out for evaporation, and the solid lithium target has poor heat dissipation, which requires high cooling performance for the overall device. Chinese patent application number CN217181818U discloses a rotating cylindrical target body container. By setting an evaporation crucible, the evaporation function of the lithium target can be realized, but the device does not have a moderator structure. Therefore, in the existing inventions and invention patents, most of them use lithium as the target material, and the target body is mostly in a fixed state, so there are the following problems:

[0005] (1) The melting point of lithium material is relatively low, about 180°C. In order to maintain its performance and extend the service life of the target, an efficient heat dissipation cooling method must be adopted. Most substrate cooling methods are not suitable for long-term operation of the target;

[0006] (2) Long-term beam irradiation will cause many irreversible damages to the target, such as foaming of the target material and the generation of impurities. Especially when the target is fixed in position, the target material needs to be replaced regularly, which increases the cost of production, manufacturing, and processing;

[0007] (3) Accelerator-driven targets are mostly independent devices that need to be assembled with moderators, reflectors and other equipment to complete neutron moderation, ensure neutron directionality and other functions. Therefore, the above-mentioned devices will occupy a certain amount of space and incur costs such as coordination and installation. Summary of the invention

[0008] In order to overcome the above-mentioned shortcomings, the present invention aims to provide a technical solution that can solve the above-mentioned problems.

[0009] A neutron target system of a vertical beam boron neutron capture therapy system comprises a target container, a rotating target and an evaporation moderation assembly. The target container is provided with an incident cavity, a target cavity and an equipment cavity which are interconnected. The top of the target container is provided with an incident port which is communicated with the incident cavity. A sealing cover plate is hinged at the incident port, and the sealing cover plate can be flipped into the incident cavity to open the incident port. The rotating target is arranged in the target cavity. The rotating target comprises a target body and a transmission shaft. The target body is cylindrical. The transmission shaft is coaxially connected with the target body. An opening which is communicated with the target cavity is arranged on the side of the target container. The transmission shaft passes through the opening and is placed outside the target container. The evaporation moderation assembly is arranged in the equipment cavity. The evaporation moderation assembly comprises a moderator, a connector and an evaporation device. The moderator and the evaporation device are connected by the connector.

[0010] As a further solution of the present invention: the rotating target also includes a target shell, which is sleeved outside the target body, and a cooling water circuit is arranged inside the target shell. The transmission shaft consists of an inner tube and an outer tube, and the outer tube is sleeved outside the inner tube. The inner tube is connected to the water inlet end of the cooling water circuit, and the outer tube is connected to the water return end of the cooling water circuit.

[0011] As a further solution of the present invention: it also includes a driving device, which is connected to the sealing cover plate through a cover plate shaft to drive the sealing cover plate to flip.

[0012] As a further solution of the present invention: the evaporation device includes a crucible, a thermal resistor evaporation source and an insulation layer.

[0013] As a further solution of the present invention: a cleaning nozzle is provided on the inner wall of the target cavity above the target body.

[0014] As a further solution of the present invention: a sliding baffle is slidably provided at the connection between the target cavity and the equipment cavity, a discharge port communicating with the equipment cavity is opened on the side of the target container, and a sealing baffle is provided at the discharge port.

[0015] As a further solution of the present invention: a film thickness monitor is also provided on the inner wall of the target cavity located above the target.

[0016] As a further solution of the present invention: a ventilation valve communicating with the target cavity is provided on the side of the target container.

[0017] As a further solution of the present invention: a sealing strip is provided on the outer edge of the incident port.

[0018] The present invention also provides a vertical beam boron neutron capture therapy system, which includes an ion source, a low-energy transmission section, an RFQ accelerator, a solid-state power source, a high-energy transmission section, a control system and the above-mentioned neutron target;

[0019] Among them, the ion source includes a source unit, a power supply unit, a microwave unit and an extraction unit. The ion source is used to ionize hydrogen and generate a proton beam. The low-energy transmission section includes a solenoid magnet and a correction magnet. The two ends of the low-energy transmission section are respectively connected to the ion source and the RFQ accelerator. The low-energy transmission section is used to transmit the beam generated by the ion source to the RFQ accelerator. The RFQ accelerator includes a cavity unit, a vacuum unit, a water cooling unit and a radio frequency power source unit. The RFQ accelerator is used to accelerate the proton beam. The solid-state power source is externally connected to the RFQ accelerator. The solid-state power source is used to further accelerate the proton beam and focus at the same time. The high-energy transmission section includes a vacuum unit, a power supply unit, a magnet unit and a beam measurement unit. The two ends of the high-energy transmission section are respectively connected to the RFQ accelerator and the neutron target, which is used to transmit the accelerated beam to the neutron target for target shooting to generate neutrons. The control system includes a hardware module and a software module. The control system is used for beam modulation of the RFQ accelerator and real-time monitoring of the status of the RFQ accelerator.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] 1. It has the function of automatic evaporation, which can regularly perform evaporation on the whole or part of the lithium target to replenish the target material and ensure the neutron production capacity of the target.

[0022] 2. It has real-time monitoring function, and the target material thickness can be monitored in real time through the film thickness monitor, which is convenient for controlling the evaporation conditions of the target body.

[0023] 3. It has an automatic cleaning function, which can regularly remove waste impurities remaining on the target to ensure efficient cooling of the target.

[0024] 4. It has an automatic drying function, which can dry the target after cleaning to ensure that the surface of the target is dry and free of impurities before the next evaporation.

[0025] 5. The above functions do not require manual operation, reducing the potential risk of human radiation during target operation and maintenance.

[0026] 6. It has the function of neutron moderation. The moderator set at the bottom of the target can directly absorb neutrons and slow them down, ensuring the maximum neutron flux that meets the experimental expectations. The moderator structure is connected to the device, saving installation space and reducing installation costs.

[0027] 7. It has a vacuum sealing function, so that the evaporation, cleaning and drying of the target can be completed in a closed vacuum environment to avoid target material damage caused by oxidation of the target.

[0028] 8. It has the function of waste collection, which can collect the waste generated by the target during operation and maintenance, and facilitate the collection and treatment of waste in the later stage.

[0029] 9. Complete the integration of target installation, evaporation, cleaning, drying, operation and other steps, and integrate the production, operation and maintenance of the target body into the same container to avoid frequent disassembly and replacement of the target body and reduce related costs.

[0030] 10. It has an automatic rotation function. By setting a cylindrical target, the surface area of ​​the target material being irradiated can be increased through its own rotation, thereby reducing the heat flux density per unit volume of the target material, improving the heat exchange efficiency of the target body, and making it easy to deal with abnormal working conditions.

[0031] 11. The shape, angle and spot size of the proton beam output by the accelerator should be lower and have a wider range of applicability.

[0032] 12. Compared with other types of rotating targets, cylindrical targets have a compact structure and small size, saving required space.

[0033] 13. The sealing door adopts an inward push structure to avoid affecting the normal irradiation of the beam during the operation of the target and ensure the neutron output efficiency.

[0034] Additional aspects and advantages of the present invention will be given in part in the following description and in part will be obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0036] Figure 1 It is a schematic diagram of the neutron target structure of the present invention.

[0037] Figure 2 It is another structural schematic diagram of the neutron target of the present invention.

[0038] Figure 3 It is a transverse cross-sectional view of the neutron target of the present invention.

[0039] Figure 4 It is a longitudinal cross-sectional view of the neutron target of the present invention.

[0040] Figure 5 It is a system principle block diagram of the present invention.

[0041] In the figure: 10, ion source, 20, low energy transmission section, 30, RFQ accelerator, 40, solid-state power source, 50, high energy transmission section, 60, control system, 70, neutron target, 1, target container, 2, rotating target, 3, evaporation moderator assembly, 4, cover shaft, 5, cleaning nozzle, 6, film thickness monitor, 7, ventilation valve, 8, sealing strip, 11, incident cavity, 12, target cavity, 13, equipment cavity, 14, incident port, 15, sealing cover, 16, discharge port, 17, sealing baffle, 18, sliding baffle, 19, opening, 21, target, 22, transmission shaft, 23, target shell, 31, moderator, 32, connector, 33, evaporation device, 221, outer tube, 222, inner tube, 231, cooling water circuit. DETAILED DESCRIPTION

[0042] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0043] Embodiment 1

[0044] See also Figures 1 to 4 In an embodiment of the present invention, a neutron target system 70 of a vertical beam boron neutron capture therapy system includes a target container 1, a rotating target 2 and a vapor deposition moderator assembly 3. The target container 1 is provided with an incident cavity 11, a target cavity 12 and an equipment cavity 13 which are interconnected. The top of the target container 1 is provided with an incident port 14 which is connected to the incident cavity 11. A sealing cover plate 15 is hinged at the incident port 14. The sealing cover plate 15 can be flipped into the incident cavity 11 to open the incident port 14. The rotating target 2 is arranged at In the target cavity 12, the rotating target 2 includes a target body 21 and a transmission shaft 22. The target body 21 is cylindrical, and the transmission shaft 22 is coaxially connected to the target body 21. An opening 19 communicating with the target cavity 12 is opened on the side of the target container 1. The transmission shaft 22 passes through the opening 19 and is placed outside the target container 1. The evaporation moderator assembly 3 is arranged in the equipment cavity 13. The evaporation moderator assembly 3 includes a moderator 31, a connector 32 and an evaporation device 33. The moderator 31 and the evaporation device 33 are connected by the connector 32.

[0045] The target container 1 serves as the outer shell of the device; the incident cavity 11, the target cavity 12 and the equipment cavity 13 provide a working environment; the target 21 generates neutrons by being irradiated by a proton beam; during the target shooting process, the sealing cover plate 15 is flipped inward to open the closed port to avoid affecting the normal irradiation of the beam during the operation of the target 21 and ensure the neutron output efficiency; the transmission shaft 22 provides kinetic energy for the target 21 and drives the target 21 to rotate. During the target shooting process, the irradiated surface area of ​​the target material can be increased by its own rotation, thereby reducing the heat flux density per unit volume of the target material, improving the heat exchange efficiency of the target 21, and making it easy to cope with abnormal working conditions; the moderator 31 is used to moderate high-energy neutrons to meet the treatment needs; the evaporation device 33 is used for evaporation of lithium targets to provide regenerated target materials for the target 21; the connector 32 is used to connect the moderator 31 and the evaporation device 33, and the moderation and evaporation work are performed by moving the two during use.

[0046] The rotating target 2 also includes a target shell 23, which is sleeved on the outside of the target body 21. A cooling water circuit 231 is arranged inside the target shell 23. The transmission shaft 22 consists of an inner tube 222 and an outer tube 221. The outer tube 221 is sleeved outside the inner tube 222. The inner tube 222 is connected to the water inlet end of the cooling water circuit 231, and the outer tube 221 is connected to the water return end of the cooling water circuit 231. Through the setting of the cooling water circuit 231, the inner tube 222 and the appearance, a cooling medium is connected to provide a cooling function for the heat exchange function of the target body 21, and removes the internal heat deposition when the target body 21 is irradiated and operated.

[0047] The device also includes a driving device, which is connected to the sealing cover plate 15 through the cover plate shaft 4 to drive the sealing cover plate 15 to flip. The driving device is provided to realize automatic control of the opening and closing of the sealing door, thereby realizing intelligent control during operation in the container cavity. The driving device includes but is not limited to a servo motor, a stepper motor, etc.

[0048] In order to satisfy the evaporation function of the target material, the evaporation device 33 includes a crucible, a thermal resistor evaporation source and a heat insulating layer.

[0049] The inner wall of the target cavity 12 is located above the target 21 and is provided with a cleaning nozzle 5 . The cleaning nozzle 5 is used to clean the waste target material generated by the target 21 and complete the cleaning work inside the target container 1 at the same time.

[0050] A sliding baffle 18 is slidably provided at the connection between the target cavity 12 and the equipment cavity 13. A discharge port 16 communicating with the equipment cavity 13 is provided on the side of the target container 1. A sealing baffle 17 is provided at the discharge port 16. The sliding baffle 11 is opened during irradiation and closed during cleaning. It is opened after cleaning to discharge waste liquid and is closed when maintenance of the moderator 31 and the evaporation device 33 is required. The sealing baffle 17 is closed during irradiation and opened after cleaning to process waste liquid and move the moderator 31 and the evaporation device 33.

[0051] The inner wall of the target cavity 12 is located above the target 21 and is also provided with a film thickness monitor 6. The film thickness monitor 6 is used to monitor the thickness of the regenerated target material on the surface of the target 21 during the evaporation operation so as to control and meet the parameter requirements.

[0052] A ventilation valve 7 communicating with the target cavity 12 is provided on the side of the target container 1. The ventilation valve 7 is used to connect external equipment, deliver high-temperature gas when drying the target 21, and connect protective gas such as argon to maintain a vacuum environment in the container cavity when abnormal conditions occur.

[0053] A sealing strip 8 is provided on the outer edge of the injection port 14 to ensure a sealed environment in the target container 1 when the sealing door is closed.

[0054] The working principle of this embodiment is:

[0055] Target evaporation: Close the sealing cover plate 15 at the top of the target container 1, move the evaporation device 33 to the bottom of the target 21, open the sliding baffle 18, and close the sealing cover plate 15 and the sealing baffle 17. Connect the vent valve 7 to the vacuum pump to evacuate the target container 1 so that the system reaches the preset deposition pressure value. Set the speed range of the target 21 to 1-100 rpm, and set the flow rate of the inlet cooling medium to control the temperature of the target 21. The evaporation device 33 is heated to evaporate the built-in spare target material. The evaporated atoms or molecules move in a straight line without collision and are rapidly transmitted to the target shell 23 to form clusters. Through contact and merging with adjacent particles, a continuous film is formed. The film thickness monitor 6 in the container monitors the target film thickness in real time. When the preset value is reached, the heating of the evaporation device 33 is stopped to complete the evaporation process of the target 21. It should be noted that the spare target material is pre-placed in the evaporation device 33 during operation, and can be replenished after the spare target material is exhausted.

[0056] Beam target shooting: Before the proton beam irradiates the target 21, the target container 1 is evacuated to a high vacuum state, the top sealing cover 15, the sliding baffle 18 and the sealing baffle 17 are opened, the moderator 31 connected to the evaporation device 33 is moved to the bottom of the target 21, and the sealing baffle 17 is closed. The speed range of the target 21 is set to 1000-10000rpm, the cooling medium inlet switch is turned on, and the inlet flow rate is adjusted to make the cooling medium flow rate reach the rated state. After the flow rate stabilizes, the accelerator system is started, and the proton beam is directly shot to the cylindrical target 21 that is performing periodic rotation through the high-energy transmission line, a spallation reaction occurs and epithermal neutrons are generated, and the beam target shooting process is completed.

[0057] Target cleaning: The target 21 will produce impurities after being irradiated with the beam for a period of time. Before cleaning the target 21, close the sealing cover 15, the sliding baffle 18 and the sealing baffle 17. Set the speed range of the target 21 to 1 to 100 rpm, then turn on the cleaning nozzle 5 to spray the built-in oxidant liquid in an atomized state. During this period, the spray continuously corrodes the metal target material and dissolves it in the oxide spray liquid to form waste liquid. After the final cleaning is completed, open the sliding baffle 18 and the sealing baffle 17, and the waste liquid is discharged through the discharge port 16. Observe the inside of the container through a visual probe. After the target 21 is cleaned until there are no residual impurities, close the cleaning nozzle 5 to complete the target 21 cleaning process.

[0058] Target drying: After the target 21 cleaning process is completed, there are residual droplets on the surface of the target 21, the target shell 23 and the inner surface of the target container 1, which becomes a safety hazard in the next evaporation process of the target 21. Before drying the target 21, open the sliding baffle 18, close the sealing cover plate 15 and the sealing baffle 17 at the upper end of the target container 1, open the ventilation valve 7 to spray high-temperature gas into the target container 1, and evaporate the residual droplets. Set the speed range of the target 21 to 100rpm. Observe through the visual probe, and when there is no liquid residue on each surface, close the ventilation valve 7 to complete the drying process of the target 21.

[0059] Embodiment 2

[0060] See also Figure 5 The present invention also provides a vertical beam boron neutron capture therapy system, which includes an ion source 10, a low energy transmission section 20, an RFQ accelerator 30, a solid-state power source 40, a high energy transmission section 50, a control system 60 and the above-mentioned neutron target 70;

[0061] The ion source 10 includes a source unit, a power supply unit, a microwave unit and an extraction unit. The ion source 10 is used to ionize hydrogen and generate a proton beam. The low-energy transmission section 20 includes a solenoid magnet and a correction magnet. The two ends of the low-energy transmission section 20 are respectively connected to the ion source 10 and the RFQ accelerator 30. The low-energy transmission section 20 is used to transmit the beam generated by the ion source 10 to the RFQ accelerator 30. The RFQ accelerator 30 includes a cavity unit, a vacuum unit, a water cooling unit and a radio frequency power source unit. The RFQ accelerator 30 is used to accelerate the proton beam. The solid-state power source 40 is externally connected to the RFQ accelerator 30, and is used to further accelerate the proton beam and focus it at the same time. The high-energy transmission section 50 includes a vacuum unit, a power supply unit, a magnet unit and a beam measurement unit. The two ends of the high-energy transmission section 50 are respectively connected to the RFQ accelerator 30 and the neutron target 70, and are used to transmit the accelerated beam to the neutron target 70 for target shooting to generate neutrons. The control system 60 includes a hardware module and a software module. The control system 60 is used for beam modulation of the RFQ accelerator 30 and real-time monitoring of the status of the RFQ accelerator 30.

[0062] The ion source 10, the low-energy transmission section 20, the RFQ accelerator 30, the solid-state power source 40, the high-energy transmission section 50 and the neutron target 70 are connected by a vacuum pipe. The proton beam generated by ionization of the ion source 10 is sent to the RFQ accelerator 30 through the low-energy transmission section 20, and after being focused and accelerated, it is sent to the high-energy transmission section 50. Finally, the proton beam passes through the high-energy transmission section 50 to irradiate the target body 21 and generate neutrons. This example is a vertical beam boron neutron capture therapy system with a compact and reasonable structure, and has the characteristics of small size, low cost, and easy installation and operation.

[0063] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be considered exemplary and non-restrictive in all respects, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention.

Claims

1. A neutron target system for a vertical beam boron neutron capture therapy system, characterized in that: include: A target container, wherein the target container is provided with an incident cavity, a target cavity and an equipment cavity which are interconnected, and the top of the target container is provided with an incident port which is connected with the incident cavity, and a sealing cover plate is hinged at the incident port, and the sealing cover plate can be turned into the incident cavity to open the incident port; A rotating target is arranged in the target body cavity. The rotating target includes a target body and a transmission shaft. The target body is cylindrical. The transmission shaft is coaxially connected to the target body. An opening communicating with the target body cavity is provided on the side of the target body container. The transmission shaft passes through the opening and is placed outside the target body container. The evaporation slowing down assembly is arranged in the equipment cavity. The evaporation slowing down assembly comprises a slowing down body, a connecting piece and an evaporation device. The slowing down body and the evaporation device are connected through the connecting piece.

2. A neutron target system for a vertical beam boron neutron capture therapy system according to claim 1, characterized in that: The rotating target also includes a target shell, which is sleeved outside the target body. A cooling water circuit is arranged inside the target shell. The transmission shaft consists of an inner tube and an outer tube, the outer tube is sleeved outside the inner tube, the inner tube is connected to the water inlet end of the cooling water circuit, and the outer tube is connected to the water return end of the cooling water circuit.

3. The neutron target system of the vertical beam boron neutron capture therapy system according to claim 1, characterized in that: It also includes a driving device, which is connected to the sealing cover plate through a cover plate shaft to drive the sealing cover plate to flip.

4. The neutron target system of the vertical beam boron neutron capture therapy system according to claim 1, characterized in that: The evaporation device comprises a crucible, a thermal resistor evaporation source and a heat insulating layer.

5. The neutron target system of the vertical beam boron neutron capture therapy system according to claim 1, characterized in that: The inner wall of the target body cavity is located above the target body and is provided with a cleaning nozzle.

6. The neutron target system of the vertical beam boron neutron capture therapy system according to claim 1, characterized in that: A sliding baffle is slidably arranged at the connection between the target cavity and the equipment cavity, a discharge port communicating with the equipment cavity is opened on the side of the target container, and a sealing baffle is arranged at the discharge port.

7. The neutron target system of the vertical beam boron neutron capture therapy system according to claim 1, characterized in that: The inner wall of the target cavity is located above the target and is also provided with a film thickness monitor.

8. The neutron target system of the vertical beam boron neutron capture therapy system according to claim 1, characterized in that: A ventilation valve communicating with the target body cavity is arranged on the side of the target body container.

9. The neutron target system of the vertical beam boron neutron capture therapy system according to claim 1, characterized in that: A sealing strip is arranged on the outer edge of the incident port.

10. A vertical beam boron neutron capture therapy system, characterized in that: The invention comprises an ion source, a low energy transmission section, an RFQ accelerator, a solid-state power source, a high energy transmission section, a control system and a neutron target system as claimed in any one of claims 1 to 9.

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