Curing skin care product containing blue copper peptide and preparation method thereof

Abstract

The invention relates to the technical field of skin care products, and particularly discloses a maintenance skin care product containing blue copper peptide and a preparation method of the maintenance skin care product. The nursing skin care product containing the copper blue peptide is formed by mixing freeze-dried powder and solvent liquid, wherein 100-230 mg of freeze-dried powder is added into every 2-5 ml of solvent liquid; the freeze-dried powder comprises the following components: water, a humectant, a skin conditioner, composite polypeptide and a pH regulator; the solvent liquid is prepared from the following components: water, a humectant, a compound extract, an antioxidant and a skin conditioner; in the solvent liquid, the compound extract is prepared by compounding a pearl extract, a cactus extract, a chlorella extract, a sphingomonas fermentation product extract, a bacillus fermentation product, a papaya fruit extract and meadowfoam seed oil. The acne-removing mask has the advantages of removing acnes and reducing acne marks at the same time.

Description

Technical Field

[0001] The invention relates to the field of skin care products, and in particular to a skin care product containing blue copper peptide and a preparation method thereof. Background Art

[0002] As people's demand for skin health and beauty grows, a large number of skin care products have appeared on the market. These products usually contain a variety of active ingredients and are designed to solve various skin problems, such as moisturizing, anti-aging, whitening, repairing, etc.

[0003] Acne is a common chronic inflammatory skin disease, which is characterized by comedones, papules, pustules, nodules, cysts and scars, accompanied by sebum secretion.

[0004] Today's acne-removing skin care products mainly control the development of acne and achieve the effect of removing acne by adding anti-inflammatory ingredients. However, acne will damage the skin structure, resulting in pits on the skin surface after the acne subsides, commonly known as acne marks. Therefore, although today's acne-removing skin care products have achieved the effect of eliminating acne to a certain extent, the effect on removing acne marks is still relatively general and it is difficult to meet the needs of consumers. Therefore, there is still room for improvement. Summary of the invention

[0005] In order to reduce the occurrence of acne marks while removing acne, the present application provides a skin care product containing blue copper peptide and a preparation method thereof.

[0006] In the first aspect, the present application provides a skin care product containing blue copper peptide, which adopts the following technical solution: A skin care product containing blue copper peptide, which is prepared by mixing freeze-dried powder and solvent liquid, wherein 100-230 mg of freeze-dried powder is added to every 2-5 ml of solvent liquid; The freeze-dried powder comprises the following components in parts by weight: Water 72.5865-86.5519 parts; Moisturizer 8.1499-16.4165 parts; Skin conditioning agent 0.1-1 part; Composite polypeptide 4.9982-7.997 parts; pH regulator 0.2-2 parts; The solvent solution includes the following components in parts by weight: Water 57.107-75.4642 parts; Moisturizer 21.0823-34.9705 parts; 2.1255-3.5425 parts of composite extract; Antioxidant 0.178-1.13 parts; Skin conditioning agent 1.15-3.25 parts; In the solvent liquid, the composite extract is a combination of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and meadowfoam seed oil.

[0007] By adopting the above technical scheme, by adding polypeptides and moisturizers, the skin can be well hydrated, thereby better regulating the water-oil balance of the skin, reducing the oil secretion of the skin, and eliminating the factors that induce acne from the root. Then, by adding a composite extract composed of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white pondweed seed oil, a good anti-inflammatory effect can be achieved, redness and swelling can be quickly removed, skin discomfort can be quickly relieved, and elastase can be well inhibited to promote the replenishment of elastin in the skin, thereby achieving skin repair in the process of acne removal, and after acne removal, the skin is not easy to leave acne marks, and the skin can be restored to be smooth and elastic, which well meets the needs of consumers.

[0008] Preferably, in the composite extract, the mass ratio of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white meadowfoam seed oil is 0.3-0.5: 0.3-0.5: 0.0255-0.0425: 0.15-0.25: 0.75-1.25: 0.3-0.5: 0.3-0.5.

[0009] By adopting the above technical scheme, by specifically selecting the mass ratios of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white meadowfoam seed oil, various active ingredients are combined in a specific ratio to exert a better synergistic effect, thereby achieving a better anti-inflammatory effect, eliminating acne more quickly, and better promoting the replenishment of skin elastin, allowing the skin to quickly restore elasticity, thereby better achieving the effect of removing acne while not leaving acne marks.

[0010] Preferably, in the lyophilized powder, the composite polypeptide is a combination of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1, and hexapeptide-1.

[0011] By adopting the above technical scheme and specifically selecting the combination of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1 and hexapeptide-1, the effect of regulating the water and oil balance of the skin is better, the repaired skin is healthier and less prone to acne.

[0012] Preferably, in the composite polypeptide, the mass ratio of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1 and hexapeptide-1 is 2-3: 0.0003-0.0005: 0.0003-0.0005: 0.0003-0.0005: 0.003-0.0005: 0.0003-0.0005: 2.994-4.99.

[0013] By adopting the above technical scheme and specifically selecting the mass ratios of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1, and hexapeptide-1, the effect of the composite polypeptide in repairing the skin is better and the skin is healthier.

[0014] Preferably, in the freeze-dried powder, the moisturizing agent is compounded by mannitol, trehalose, butylene glycol, 1,2-hexanediol, ethylhexylglycerol, dimethyl isosorbide, and 1,2-pentanediol in a mass ratio of 5-10: 0.5-2: 1.8-3: 0.4833-0.8055: 0.0066-0.011: 0.3-0.5: 0.06-0.1; in the solvent solution, the moisturizing agent is polyglutamic acid, butylene glycol, sodium hyaluronate, β-glucan, ethylhexylglycerol, 1,3-propylene glycol, lactic acid, panthenol, glycerol, caprylic / capric glycerol Triglyceride, hydrogenated lecithin, phytosterol / octyldodecanol lauroyl glutamate, ceramide NP and 1,2-hexanediol are compounded in the mass ratio of 1-2: 11.95-18.25: 1.0003-2.0005: 0.03-0.05: 0.0063-0.0105: 0.6-1: 0.006-0.01: 3-5: 2.5947-4.3245: 0.45-0.75: 0.15-0.25: 0.03-0.05: 0.015-0.025: 0.25-1.2.

[0015] By adopting the above technical solution, the moisturizing effect is improved, the water and oil balance of the skin can be adjusted more permanently, and the inducing factors of acne can be eliminated better from the root, making the skin healthier and less likely to breed acne again.

[0016] Preferably, in the freeze-dried powder, the skin conditioner is sodium chloride; in the solvent solution, the skin conditioner is compounded by tripeptide-1 copper and protease in a mass ratio of 1-3:0.15-0.25.

[0017] By adopting the above technical solution, the skin care effect of skin care products is better, the skin repair effect is more effective, and the repaired skin is healthier.

[0018] Preferably, in the freeze-dried powder, the pH adjuster is prepared by mixing disodium hydrogen phosphate and sodium dihydrogen phosphate in a mass ratio of 0.1-1:0.1-1.

[0019] By adopting the above technical solution, skin care products are made gentler, feel more comfortable when used on the skin, and irritation to the skin is effectively reduced, reducing skin discomfort.

[0020] Preferably, in the solvent liquid, the antioxidant is prepared by compounding phenoxyethanol and p-hydroxyacetophenone in a mass ratio of 0.054-0.09:0.124-1.04.

[0021] By adopting the above technical solution, the shelf life of skin care products is prolonged, the irritation to the skin is reduced, the product safety is higher, and it has higher economic value.

[0022] In a second aspect, the present application provides a method for preparing a skin care product containing blue copper peptide, using the following technical solution: A method for preparing the above-mentioned skin care product containing blue copper peptide includes a freeze-dried powder preparation method and a solvent liquid preparation method; the freeze-dried powder preparation method is as follows: The components are mixed evenly according to the proportion, the material is filtered out and then dried by vacuum freeze drying equipment to obtain freeze-dried powder; The solvent solution preparation method is as follows: Mix the components evenly according to the proportion, filter the material and obtain the solvent solution.

[0023] By adopting the above technical solution, the prepared skin care products containing blue copper peptides can quickly eliminate acne, and while eliminating acne, can effectively reduce the occurrence of acne marks, making the repaired skin more elastic and smoother, and the effect of repairing the skin is more significant, which well meets the needs of consumers.

[0024] In summary, this application has the following beneficial effects: 1. Since the present application can well hydrate the skin by adding polypeptides and moisturizers, it can better regulate the water-oil balance of the skin, reduce the oil secretion of the skin, and eliminate the factors that induce acne from the root, and then by adding pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, Bacillus fermentation product, papaya fruit extract, and white pondweed seed oil to form a composite extract, it can achieve a good anti-inflammatory effect, can quickly remove redness and swelling, quickly relieve skin discomfort, and can play a good role in inhibiting elastase, promote the supplement of elastin in the skin, so that the skin can be repaired in the process of acne removal, so that after the acne removal is completed, the skin is not easy to leave acne marks, and the skin can be restored to be smooth and elastic, which well meets the needs of consumers.

[0025] 2. In the present application, it is preferred to specifically select the mass ratio of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white meadowfoam seed oil so that various active ingredients are matched in a specific ratio to exert a better synergistic effect, thereby making the anti-inflammatory effect better, eliminating acne more quickly, and better promoting the replenishment of skin elastin, so that the skin quickly restores elasticity, thereby better achieving the effect of removing acne without leaving acne marks.

[0026] 3. In this application, it is preferred to specifically select a combination of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1, and hexapeptide-1 to better regulate the water and oil balance of the skin, and the repaired skin is healthier and less prone to acne. DETAILED DESCRIPTION

[0027] The present application is further described in detail below with reference to the embodiments.

[0028] Example 1 A skin care product containing blue copper peptide is prepared by mixing freeze-dried powder and solvent liquid, with 100 mg of freeze-dried powder added to every 2 ml of solvent liquid.

[0029] The lyophilized powder is prepared from the following components: Water, moisturizer, skin conditioner, complex polypeptide, pH adjuster.

[0030] The moisturizer is a compound of mannitol, trehalose, butylene glycol, 1,2-hexanediol, ethylhexylglycerin, dimethyl isosorbide and 1,2-pentanediol.

[0031] The skin conditioning agent is sodium chloride.

[0032] The complex polypeptide is a combination of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1, and hexapeptide-1.

[0033] The pH adjuster is a compound of disodium hydrogen phosphate and sodium dihydrogen phosphate.

[0034] The preparation method of freeze-dried powder is as follows: Step 1), water, mannitol, trehalose, sodium chloride, disodium hydrogen phosphate and sodium dihydrogen phosphate are put into a stirring kettle, the speed is 100 r / min, stirring is continued, heating to 85° C., and stirring is maintained at this temperature for 30 minutes to obtain a premix.

[0035] Step 2), cooling the premix to 40°C, then adding tripeptide-1 copper to the premix, rotating at 100 r / min, stirring for 5 min, to obtain a mixture.

[0036] Step 3), add butanediol, 1,2-hexanediol, ethylhexylglycerol, palmitoyl tetrapeptide-7, isosorbide anhydride dimethyl ether, palmitoyl tripeptide-1, palmitoyl tripeptide-5, 1,2-pentanediol, tetrapeptide-1, nonapeptide-1, hexapeptide-1 to the mixture, rotate at 100 r / min, stir for 5 minutes, filter the material with a 500 mesh filter cloth to obtain a wet material.

[0037] Step 4), the wet material is transferred into a vacuum freeze dryer and freeze-dried at -45°C to obtain freeze-dried powder.

[0038] The specific input amount of each raw material in the freeze-dried powder preparation method of this embodiment is shown in Table 1.

[0039] The source information of each raw material in the freeze-dried powder preparation method of this embodiment is detailed in Table 2.

[0040] The solvent solution is prepared from the following components: Water, moisturizer, complex extract, antioxidant, skin conditioner.

[0041] The moisturizer is a combination of polyglutamic acid, butylene glycol, sodium hyaluronate, β-glucan, ethylhexylglycerin, 1,3-propylene glycol, lactic acid, panthenol, glycerin, caprylic / capric triglyceride, hydrogenated lecithin, phytosteryl / octyldodecanol lauroyl glutamate, ceramide NP, and 1,2-hexanediol.

[0042] The compound extract is a combination of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white meadowfoam seed oil. The antioxidant is a compound of phenoxyethanol and p-hydroxyacetophenone.

[0043] The skin conditioning agent is a combination of tripeptide-1 copper and protease.

[0044] The preparation method of the solvent solution is as follows: Step 1), p-hydroxyacetophenone, butanediol and 1,2-hexanediol are put into a stirring kettle, the temperature is raised to 60°C, the speed is 60r / min, and the mixture is stirred and dissolved completely until transparent and free of particles to obtain a premix for standby use.

[0045] Step 2), add water, polyglutamic acid, sodium hyaluronate into an emulsifying pot, heat to 85°C, 2200r / min, homogenize for 1min, rotate at 100r / min, keep at 85°C, stir for 20min to obtain a mixture.

[0046] Step 3), the mixture is cooled to 40 ° C, and then the premix, β-glucan, ethylhexylglycerin, pearl extract, phenoxyethanol, cactus extract, 1,3-propylene glycol, chlorella extract, lactic acid, sphingomonas fermentation product extract, panthenol, tripeptide-1 copper, glycerol, caprylic / capric triglyceride, hydrogenated lecithin, phytosterol / octyldodecanol lauroyl glutamate ceramide, Bacillus fermentation product, protease, papaya fruit extract, and white meadowfoam seed oil are added to the mixture, the speed is 100 r / min, the mixture is stirred for 10 min, and the material is filtered with a 500 mesh filter cloth to obtain a solvent solution.

[0047] The specific input amount of each raw material in the solvent solution preparation method of this embodiment is detailed in Table 3.

[0048] The source information of each raw material in the solvent solution preparation method of this embodiment is detailed in Table 4.

[0049] Example 2 A skin care product containing blue copper peptide is prepared by mixing freeze-dried powder and solvent liquid, with 180 mg of freeze-dried powder added to every 3 ml of solvent liquid.

[0050] The lyophilized powder is prepared from the following components: Water, moisturizer, skin conditioner, complex polypeptide, pH adjuster.

[0051] The moisturizer is a compound of mannitol, trehalose, butylene glycol, 1,2-hexanediol, ethylhexylglycerin, dimethyl isosorbide and 1,2-pentanediol.

[0052] The skin conditioning agent is sodium chloride.

[0053] The complex polypeptide is a combination of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1, and hexapeptide-1.

[0054] The pH adjuster is a compound of disodium hydrogen phosphate and sodium dihydrogen phosphate.

[0055] The preparation method of freeze-dried powder is as follows: Step 1), water, mannitol, trehalose, sodium chloride, disodium hydrogen phosphate and sodium dihydrogen phosphate are put into a stirring kettle, the speed is 110 r / min, stirring is continued, heating to 86° C., and stirring is maintained at this temperature for 33 minutes to obtain a premix.

[0056] Step 2), cooling the premix to 42°C, then adding tripeptide-1 copper to the premix, rotating at 110 r / min, stirring for 8 min, to obtain a mixture.

[0057] Step 3), add butanediol, 1,2-hexanediol, ethylhexylglycerol, palmitoyl tetrapeptide-7, isosorbide anhydride dimethyl ether, palmitoyl tripeptide-1, palmitoyl tripeptide-5, 1,2-pentanediol, tetrapeptide-1, nonapeptide-1, hexapeptide-1 to the mixture, rotate at 110 r / min, stir for 8 minutes, filter the material with a 500 mesh filter cloth to obtain a wet material.

[0058] Step 4), the wet material is transferred into a vacuum freeze dryer and freeze-dried at -45°C to obtain freeze-dried powder.

[0059] The specific input amount of each raw material in the freeze-dried powder preparation method of this embodiment is shown in Table 1.

[0060] The source information of each raw material in the freeze-dried powder preparation method of this embodiment is detailed in Table 2.

[0061] The solvent solution is prepared from the following components: Water, moisturizer, complex extract, antioxidant, skin conditioner.

[0062] The moisturizer is a combination of polyglutamic acid, butylene glycol, sodium hyaluronate, β-glucan, ethylhexylglycerin, 1,3-propylene glycol, lactic acid, panthenol, glycerin, caprylic / capric triglyceride, hydrogenated lecithin, phytosteryl / octyldodecanol lauroyl glutamate, ceramide NP, and 1,2-hexanediol.

[0063] The compound extract is a combination of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white meadowfoam seed oil. The antioxidant is a compound of phenoxyethanol and p-hydroxyacetophenone.

[0064] The skin conditioning agent is a combination of tripeptide-1 copper and protease.

[0065] The preparation method of the solvent solution is as follows: Step 1), p-hydroxyacetophenone, butanediol and 1,2-hexanediol are put into a stirring kettle, the temperature is raised to 62° C., the speed is 70 r / min, and the mixture is stirred and dissolved completely until transparent and free of particles to obtain a premix for standby use.

[0066] Step 2), add water, polyglutamic acid, sodium hyaluronate into an emulsifying pot, heat to 88°C, 2350r / min, homogenize for 1.5min, rotate at 110r / min, keep at 88°C, stir for 22min, and obtain a mixture.

[0067] Step 3), the mixture is cooled to 42 ° C, and then the premix, β-glucan, ethylhexylglycerin, pearl extract, phenoxyethanol, cactus extract, 1,3-propylene glycol, chlorella extract, lactic acid, sphingomonas fermentation product extract, panthenol, tripeptide-1 copper, glycerol, caprylic / capric triglyceride, hydrogenated lecithin, phytosterol / octyldodecanol lauroyl glutamate ceramide, Bacillus fermentation product, protease, papaya fruit extract, and white meadowfoam seed oil are added to the mixture at a speed of 110 r / min, stirred for 12 min, and filtered with a 500-mesh filter cloth to obtain a solvent solution.

[0068] The specific input amount of each raw material in the solvent solution preparation method of this embodiment is detailed in Table 3.

[0069] The source information of each raw material in the solvent solution preparation method of this embodiment is detailed in Table 4.

[0070] Example 3 A skin care product containing blue copper peptide is prepared by mixing freeze-dried powder and solvent liquid, wherein 230 mg of freeze-dried powder is added to every 5 ml of solvent liquid.

[0071] The lyophilized powder is prepared from the following components: Water, moisturizer, skin conditioner, complex polypeptide, pH adjuster.

[0072] The moisturizer is a compound of mannitol, trehalose, butylene glycol, 1,2-hexanediol, ethylhexylglycerin, dimethyl isosorbide and 1,2-pentanediol.

[0073] The skin conditioning agent is sodium chloride.

[0074] The complex polypeptide is a combination of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1, and hexapeptide-1.

[0075] The pH adjuster is a compound of disodium hydrogen phosphate and sodium dihydrogen phosphate.

[0076] The preparation method of freeze-dried powder is as follows: Step 1), water, mannitol, trehalose, sodium chloride, disodium hydrogen phosphate and sodium dihydrogen phosphate are put into a stirring kettle, the speed is 120r / min, stirring is continued, heating to 88°C, and stirring is maintained at this temperature for 35 minutes to obtain a premix.

[0077] Step 2), cooling the premix to 45°C, then adding tripeptide-1 copper to the premix, rotating at 120 r / min, stirring for 10 min, to obtain a mixture; Step 3), add butanediol, 1,2-hexanediol, ethylhexylglycerol, palmitoyl tetrapeptide-7, isosorbide anhydride dimethyl ether, palmitoyl tripeptide-1, palmitoyl tripeptide-5, 1,2-pentanediol, tetrapeptide-1, nonapeptide-1, hexapeptide-1 to the mixture, rotate at 120 r / min, stir for 10 minutes, filter the material with a 500 mesh filter cloth to obtain a wet material.

[0078] Step 4), the wet material is transferred into a vacuum freeze dryer and freeze-dried at -45°C to obtain freeze-dried powder.

[0079] The specific input amount of each raw material in the freeze-dried powder preparation method of this embodiment is shown in Table 1.

[0080] The source information of each raw material in the freeze-dried powder preparation method of this embodiment is detailed in Table 2.

[0081] The solvent solution is prepared from the following components: Water, moisturizer, complex extract, antioxidant, skin conditioner.

[0082] The moisturizer is a combination of polyglutamic acid, butylene glycol, sodium hyaluronate, β-glucan, ethylhexylglycerin, 1,3-propylene glycol, lactic acid, panthenol, glycerin, caprylic / capric triglyceride, hydrogenated lecithin, phytosteryl / octyldodecanol lauroyl glutamate, ceramide NP, and 1,2-hexanediol.

[0083] The compound extract is a combination of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white meadowfoam seed oil. The antioxidant is a compound of phenoxyethanol and p-hydroxyacetophenone.

[0084] The skin conditioning agent is a combination of tripeptide-1 copper and protease.

[0085] The preparation method of the solvent solution is as follows: Step 1), p-hydroxyacetophenone, butanediol and 1,2-hexanediol are put into a stirring kettle, the temperature is raised to 65°C, the speed is 80r / min, and the mixture is stirred and dissolved completely until transparent and free of particles to obtain a premix for standby use.

[0086] Step 2), add water, polyglutamic acid, sodium hyaluronate into an emulsifying pot, heat to 90°C, 2500r / min, homogenize for 2min, rotate at 120r / min, keep at 90°C, stir for 25min to obtain a mixture.

[0087] Step 3), the mixture is cooled to 45 ° C, and then the premix, β-glucan, ethylhexylglycerin, pearl extract, phenoxyethanol, cactus extract, 1,3-propylene glycol, chlorella extract, lactic acid, sphingomonas fermentation product extract, panthenol, tripeptide-1 copper, glycerol, caprylic / capric triglyceride, hydrogenated lecithin, phytosterol / octyldodecanol lauroyl glutamate ceramide, Bacillus fermentation product, protease, papaya fruit extract, and white meadowfoam seed oil are added to the mixture, the speed is 120 r / min, the mixture is stirred for 15 min, and the material is filtered with a 500 mesh filter cloth to obtain a solvent solution.

[0088] The specific input amount of each raw material in the solvent solution preparation method of this embodiment is detailed in Table 3.

[0089] The source information of each raw material in the solvent solution preparation method of this embodiment is detailed in Table 4.

[0090] Table 1. Specific input amount of each raw material in the freeze-dried powder preparation method of Examples 1-3, unit (kg) Table 2. Source information of raw materials in the freeze-dried powder preparation method of Examples 1-3 Table 3. Specific input amount of each raw material in the solvent solution preparation method of Examples 1-3, unit (kg) Table 4. Source information of each raw material in the solvent solution preparation method of Examples 1-3 Comparative Example 1 A skin care product containing blue copper peptide, compared with Example 2, the only difference is that in the solvent liquid, witch hazel extract is used to replace pearl extract in an equal amount.

[0091] The witch hazel extract was purchased from Shanyang Lianfeng Biotechnology Co., Ltd.

[0092] Comparative Example 2 A skin care product containing blue copper peptide, compared with Example 2, the only difference is that in the solvent liquid, an equal amount of aloe vera extract is used to replace the cactus extract.

[0093] Aloe vera extract was purchased from Sichuan Huanxu Biotechnology Co., Ltd.

[0094] Comparative Example 3 A skin care product containing blue copper peptide, compared with Example 2, the only difference is that in the solvent liquid, an equal amount of chamomile extract is used to replace the chlorella extract.

[0095] Chamomile extract was purchased from Xi'an Anao Biotechnology Co., Ltd.

[0096] Comparative Example 4 A skin care product containing blue copper peptide, compared with Example 2, the only difference is that in the solvent liquid, saffron extract is used to replace the sphingomonas fermentation product extract in an equal amount.

[0097] Saffron extract was purchased from Xi'an Youshuo Biotechnology Co., Ltd.

[0098] Comparative Example 5 A skin care product containing blue copper peptide, compared with Example 2, the only difference is that in the solvent liquid, lavender extract is used to replace the Bacillus fermentation product in an equal amount.

[0099] Lavender extract was purchased from Xi'an Anao Biotechnology Co., Ltd.

[0100] Comparative Example 6 A skin care product containing blue copper peptides, compared with Example 2, the only difference is that in the solvent liquid, an equal amount of Centella asiatica extract is used to replace the papaya fruit extract.

[0101] Centella asiatica extract was purchased from Xi'an Wuling Biotechnology Co., Ltd.

[0102] Comparative Example 7 A skin care product containing blue copper peptide, which is different from Example 2 only in that: In the solvent solution, tea tree essential oil was used to replace white meadowfoam seed oil in an equal amount.

[0103] Tea tree essential oil was purchased from Jiangsu Runfeng Synthetic Technology Co., Ltd.

[0104] Comparative Example 8 A skin care product containing blue copper peptide, which is different from Example 2 only in that: In the solvent solution, witch hazel extract was used to replace pearl extract in an equal amount, aloe vera extract was used to replace cactus extract in an equal amount, chamomile extract was used to replace chlorella extract in an equal amount, saffron extract was used to replace Sphingomonas fermentation product extract in an equal amount, lavender extract was used to replace Bacillus fermentation product in an equal amount, Centella asiatica extract was used to replace papaya fruit extract in an equal amount, and tea tree essential oil was used to replace white meadowfoam seed oil in an equal amount.

[0105] The witch hazel extract was purchased from Shanyang Lianfeng Biotechnology Co., Ltd.

[0106] Aloe vera extract was purchased from Sichuan Huanxu Biotechnology Co., Ltd.

[0107] Chamomile extract was purchased from Xi'an Anao Biotechnology Co., Ltd.

[0108] Saffron extract was purchased from Xi'an Youshuo Biotechnology Co., Ltd.

[0109] Lavender extract was purchased from Xi'an Anao Biotechnology Co., Ltd.

[0110] Centella asiatica extract was purchased from Xi'an Wuling Biotechnology Co., Ltd.

[0111] Tea tree essential oil was purchased from Jiangsu Runfeng Synthetic Technology Co., Ltd.

[0112] Experiment 1 Recruit a number of volunteers, aged 20-30 years old, all with acne symptoms and no less than 10 pimples on their faces, and randomly divide the volunteers into groups of ten. Before conducting the experiment, count the number of pimples on the faces of each group of volunteers, take the average, and record it as the initial number of pimples.

[0113] The volunteers were divided into groups and used the maintenance skin care products containing blue copper peptides of each embodiment and comparative example once every night. When using, 3 ml of the solvent solution was mixed with 180 mg of the freeze-dried powder to form a maintenance skin care product containing blue copper peptides, and then the skin care product was evenly applied to the face until it was completely absorbed.

[0114] After 30 days of continuous use, the number of acne on the faces of volunteers in each group was counted again and the average was taken.

[0115] Experiment 2 The elastase inhibition rate of the skin care products containing blue copper peptide in each embodiment and comparative example was detected.

[0116] 1. Instruments, Equipment and Reagents 1.1 Instruments and equipment: Analytical balance; Full wavelength multifunctional microplate reader.

[0117] 1.2 Reagents and consumables: Tris(hydroxymethyl)aminomethane (AR); Concentrated hydrochloric acid (GR); Elastase (30 U / mg); EGCG (epigallocatechin gallate); AAAPAN(AR).

[0118] 1.3 Test sample: the skin care products containing blue copper peptide in each embodiment and comparative example, prepared and tested according to the ratio of solvent solution to lyophilized powder recorded in each embodiment and comparative example; Negative control: pure water; Positive control: EGCG solution.

[0119] 2. Test method: Four groups, ABCD, were set up respectively, with 3 parallels in each group. Buffer solution, sample solution, enzyme solution and substrate were added to the 96-well plate in sequence, and the 96-well plate was placed in a low-temperature oscillating water tank at a certain temperature, and the oscillation mode was turned on. After the solution inside reacted completely, the absorbance value of each group was measured at a wavelength of 410nm.

[0120] 3. Calculation formula Where: A—is the absorbance of the reaction solution containing sample and enzyme; B—is the absorbance of the reaction solution containing sample and without enzyme; C—is the absorbance of the reaction solution containing enzyme but not sample; D—is the absorbance of the reaction solution without sample and enzyme.

[0121] The specific test data of Experiments 1 and 2 are shown in Table 1.

[0122] Table 1 According to the data comparison of each embodiment and comparative example in Table 1, each embodiment and comparative example can have a good anti-inflammatory effect and can effectively reduce the number of acne, and the elastase inhibition rate of each embodiment is significantly higher than that of each comparative example. It can be seen that each embodiment can not only eliminate acne, but also repair the skin synchronously, promote the skin to supplement elastin, so that acne is eliminated while reducing the generation of acne marks, and the skin after acne removal is more elastic and smoother.

[0123] Each comparative example uses a conventional extract with acne-removing effect to replace the pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white meadowfoam seed oil in each embodiment. Although the acne-removing effect is also good, the special compound of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and white meadowfoam seed oil is destroyed, resulting in a general effect of inhibiting elastase, and it is difficult to achieve the effect of removing acne while reducing acne marks.

[0124] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.

Claims

1. A skin care product containing blue copper peptide, characterized in that: It is made by mixing freeze-dried powder and solvent liquid, adding 100-230mg freeze-dried powder to every 2-5ml solvent liquid; The freeze-dried powder comprises the following components in parts by weight: Water 72.5865-86.5519 parts; Moisturizer 8.1499-16.4165 parts; Skin conditioning agent 0.1-1 part; Composite polypeptide 4.9982-7.997 parts; pH regulator 0.2-2 parts; The solvent solution includes the following components in parts by weight: Water 57.107-75.4642 parts; Moisturizer 21.0823-34.9705 parts; 2.1255-3.5425 parts of composite extract; Antioxidant 0.178-1.13 parts; Skin conditioning agent 1.15-3.25 parts; In the solvent liquid, the composite extract is a combination of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract, and meadowfoam seed oil.

2. A skin care product containing blue copper peptide according to claim 1, characterized in that: In the composite extract, the mass ratios of pearl extract, cactus extract, chlorella extract, sphingomonas fermentation product extract, bacillus fermentation product, papaya fruit extract and meadowfoam seed oil are 0.3-0.5: 0.3-0.5: 0.0255-0.0425: 0.15-0.25: 0.75-1.25: 0.3-0.5: 0.3-0.

5.

3. A skin care product containing blue copper peptide according to claim 1, characterized in that: In the lyophilized powder, the composite polypeptide is a compound of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1, and hexapeptide-1.

4. A skin care product containing blue copper peptide according to claim 3, characterized in that: In the composite polypeptide, the mass ratio of tripeptide-1 copper, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, tetrapeptide-1, nonapeptide-1 and hexapeptide-1 is 2-3: 0.0003-0.0005: 0.0003-0.0005: 0.0003-0.0005: 0.003-0.0005: 0.0003-0.0005: 2.994-4.

99.

5. A skin care product containing blue copper peptide according to claim 1, characterized in that: In the freeze-dried powder, the moisturizing agent is compounded by mannitol, trehalose, butylene glycol, 1,2-hexanediol, ethylhexylglycerol, dimethyl isosorbide, and 1,2-pentanediol in a mass ratio of 5-10: 0.5-2: 1.8-3: 0.4833-0.8055: 0.0066-0.011: 0.3-0.5: 0.06-0.1; in the solvent solution, the moisturizing agent is polyglutamic acid, butylene glycol, sodium hyaluronate, β-glucan, ethylhexylglycerol, 1,3-propylene glycol, lactic acid, panthenol, glycerol, caprylic / capric triglyceride. Ester, hydrogenated lecithin, phytosterol / octyldodecanol lauroyl glutamate, ceramide NP, and 1,2-hexanediol are compounded in a mass ratio of 1-2: 11.95-18.25: 1.0003-2.0005: 0.03-0.05: 0.0063-0.0105: 0.6-1: 0.006-0.01: 3-5: 2.5947-4.3245: 0.45-0.75: 0.15-0.25: 0.03-0.05: 0.015-0.025: 0.25-1.

2.

6. A skin care product containing blue copper peptide according to claim 1, characterized in that: In the freeze-dried powder, the skin conditioner is sodium chloride; in the solvent solution, the skin conditioner is prepared by compounding tripeptide-1 copper and protease in a mass ratio of 1-3:0.15-0.

25.

7. A skin care product containing blue copper peptide according to claim 1, characterized in that: In the freeze-dried powder, the pH regulator is prepared by mixing disodium hydrogen phosphate and sodium dihydrogen phosphate in a mass ratio of 0.1-1:0.1-1.

8. A skin care product containing blue copper peptide according to claim 1, characterized in that: In the solvent liquid, the antioxidant is prepared by compounding phenoxyethanol and p-hydroxyacetophenone in a mass ratio of 0.054-0.09:0.124-1.

04.

9. A method for preparing a skin care product containing blue copper peptide according to any one of claims 1 to 8, characterized in that: Including freeze-dried powder preparation method and solvent liquid preparation method; The freeze-dried powder preparation method is as follows: The components are mixed evenly according to the proportion, the material is filtered out and then dried by vacuum freeze drying equipment to obtain freeze-dried powder; The solvent solution preparation method is as follows: Mix the components evenly according to the proportion, filter the material and obtain the solvent solution.

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