Preparation method of blood-activating and blood-stasis-removing dressing and dressing

Abstract

A method for preparing a blood-activating and stasis-removing dressing includes the following steps: First, EVAL powder is evenly sprinkled on PP spunbond fabric. Then, the side of the PP spunbond fabric with EVAL powder is laminated with a PE spunbond film to obtain an SF film composite material. Next, the SF film composite material is made into an open bag, and then an appropriate amount of iron powder and carbon powder are filled into the bag before sealing it to obtain a chemical heat-removing pack. The chemical heat-removing pack is then laminated into a pure cotton spunlace nonwoven fabric. Finally, a flash-evaporated nonwoven fabric is laminated on top of the pure cotton spunlace nonwoven fabric to obtain a heat-generating nonwoven fabric. First, PVA solution and carboxymethyl chitosan solution are prepared separately. Then, an appropriate amount of PVA solution and carboxymethyl chitosan solution are mixed evenly, and an appropriate amount of magnesium sulfate solution is added and stirred evenly. After standing, the mixture is cooled and solidified to obtain a skin-friendly hydrogel. The skin-friendly hydrogel is then adhered to the bottom of the heat-generating nonwoven fabric to obtain the blood-activating and stasis-removing dressing. This invention can maintain a stable temperature.

Description

Technical Field

[0001] This invention relates to an improvement in the preparation of a blood-activating and stasis-removing dressing, belonging to the medical field, and particularly to a method for preparing the blood-activating and stasis-removing dressing and the dressing itself. Background Art

[0002] Phlebitis refers to acute aseptic inflammation of veins. Depending on the location of the lesion, phlebitis can be divided into superficial phlebitis and deep phlebitis. Its pathological changes include intimal hyperplasia, narrowing of the lumen of the blood vessel, and slowing of blood flow. Patients often experience pain and inflammatory symptoms. Applying heat at a suitable temperature can promote vasodilation and congestion, accelerate the body's metabolism, effectively relieve symptoms, and promote the dissipation of inflammation. Therefore, heat application is used in current technology to treat phlebitis.

[0003] The most common method of applying heat in existing technologies is to dissolve a certain amount of magnesium sulfate in warm water to obtain a magnesium sulfate solution, then soak medical gauze in the magnesium sulfate solution, and then take out the magnesium sulfate gauze carrying a certain amount of heat. Then, relevant personnel use the magnesium sulfate gauze to apply heat to the patient. However, the magnesium sulfate gauze obtained by this method has a short heat retention time, dissipates heat quickly, and the heating temperature cannot be maintained at a stable state, resulting in poor effect in relieving inflammation.

[0004] Chinese patent application CN202410242637.5, filed on March 4, 2024, discloses a biomedical hydrogel composite material and its preparation method. The formulation includes: polyvinyl alcohol hydrogel, graphene composite hydrogel, phase change hydrogel, and traditional Chinese medicine liquid composite hydrogel. The weight parts of each component are: 3-30 parts of polyvinyl alcohol hydrogel, 1-10 parts of graphene composite hydrogel, 10-50 parts of phase change hydrogel, and 5-30 parts of traditional Chinese medicine liquid. A compound hydrogel; preparation method, including the following steps: Step 1, material preparation; Step 2, coating; Step 3, slitting; Step 4, storage; By coating polyvinyl alcohol-based hydrogel, graphene compound hydrogel, phase change hydrogel and traditional Chinese medicine liquid compound hydrogel onto non-woven fabric, it becomes a medical polymer bandage that can be used for cold or hot compresses. This bandage improves the quality of the bandage. However, the above technology only records that the biomedical hydrogel can be used for hot compresses, without any record of how to maintain temperature stability.

[0005] The information disclosed in this background section is intended only to enhance the understanding of the overall background of this patent application and should not be construed as an admission or in any way implying that the information constitutes prior art known to those skilled in the art. Summary of the Invention

[0006] The purpose of this invention is to overcome the problem of difficulty in maintaining a stable temperature in the prior art, and to provide a method for preparing a blood-activating and stasis-removing dressing that can maintain a stable temperature, as well as the dressing itself.

[0007] To achieve the above objectives, the technical solution of the present invention is: a method for preparing a blood-activating and stasis-removing dressing, the method comprising the following steps:

[0008] The first step is to evenly sprinkle EVAL powder onto PP spunbond fabric, and then laminate the side of the PP spunbond fabric with EVAL powder onto PE spunbond film to obtain SF film composite material.

[0009] The second step is to first make an open cloth bag from SF film composite material, then fill the cloth bag with an appropriate amount of iron powder and carbon powder and seal it to obtain a chemical heat pack. Then, the chemical heat pack is laminated into a pure cotton spunlace nonwoven fabric, and then a flash nonwoven fabric is laminated on top of the pure cotton spunlace nonwoven fabric.

[0010] The third step is to first prepare PVA solution and carboxymethyl chitosan solution separately, then take an appropriate amount of PVA solution and carboxymethyl chitosan solution and mix them evenly, then add an appropriate amount of magnesium sulfate solution and stir evenly. After standing, the mixture will solidify and form a skin-friendly hydrogel.

[0011] Step 4: Adhere the skin-friendly hydrogel to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and stasis-removing dressing.

[0012] In the first step, EVAL powder is first evenly sprinkled on PP spunbond fabric, and then the side of the PP spunbond fabric with EVAL powder is laminated with PE spunbond film to obtain SF film composite material. Specifically, EVAL powder is evenly sprinkled on the prepared PP spunbond fabric, and then the powder is melted by heating and introduced into the PE breathable membrane. Hot melt adhesive is impregnated on the surface of the two materials, and then pressure is applied using a laminating machine to solidify the hot melt adhesive in a short time, so that the PP spunbond fabric and PE breathable membrane are bonded together to become SF film composite material.

[0013] In the second step, the appropriate amount of iron powder and carbon powder is as follows: the mass percentage of iron powder to carbon powder is 5-20: carbon powder 1-10.

[0014] In the second step, the chemical heat pack is further laminated inside the pure cotton spunlace nonwoven fabric. Specifically, the upper layer is pure cotton spunlace nonwoven fabric, the middle layer is the chemical heat pack, and the lower layer is pure cotton spunlace nonwoven fabric. The upper and lower layers of pure cotton spunlace nonwoven fabric wrap the chemical heat pack inside.

[0015] The chemical heat pack has a heating rate of 8℃ / min to 14℃ / min, a temperature of 31℃ to 65℃, and a continuous heating time of 140 minutes to 201 minutes.

[0016] The pure cotton spunlace nonwoven fabric and the flash nonwoven fabric have the same length and width, but the length and width of the pure cotton spunlace nonwoven fabric are greater than those of the skin-friendly hydrogel.

[0017] Both the pure cotton spunlace nonwoven fabric and the flash-steamed nonwoven fabric are 15cm×15cm squares, and the magnesium sulfate skin-friendly hydrogel is a 5×5cm square.

[0018] In the third step, the mass fraction of the PVA solution is 5%–20%, the mass fraction of the carboxymethyl chitosan solution is 5%–20%, and the mass fraction of the magnesium sulfate solution is 10%–40%.

[0019] The volume ratio of the PVA solution, carboxymethyl chitosan solution, and magnesium sulfate solution is 2-15:2-15:0.1-1.

[0020] The PVA solution is prepared as follows: 5-15g of polyvinyl alcohol is placed in 40g of deionized water, heated and ultrasonically treated for 5min to obtain the PVA solution;

[0021] The preparation method of the carboxymethyl chitosan solution is as follows: then take 5-15g of carboxymethyl chitosan and place it in 40g of deionized water to obtain the carboxymethyl chitosan solution;

[0022] The magnesium sulfate solution is prepared as follows: 10-50g of magnesium sulfate is dissolved in warm water at 40℃ to obtain a magnesium sulfate solution;

[0023] The process of obtaining a skin-friendly hydrogel by cooling and solidifying after static conditions is as follows: magnesium sulfate solution is ultrasonically treated for 5 minutes, poured into a mold, and then cooled and solidified for 12 hours to obtain a skin-friendly hydrogel.

[0024] A blood-activating and stasis-removing dressing is prepared using the above-mentioned preparation method. The blood-activating and stasis-removing dressing includes a flash-evaporated nonwoven fabric, a pure cotton spunlace nonwoven fabric, a heat pack, and a skin-friendly hydrogel. The flash-evaporated nonwoven fabric is placed on top of the pure cotton spunlace nonwoven fabric, the heat pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is placed at the bottom of the pure cotton spunlace nonwoven fabric.

[0025] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0026] 1. In the preparation method of the blood-activating and stasis-removing dressing of the present invention, the skin-friendly hydrogel in the dressing is first applied to the wound, and then the entire dressing is fixed. Since the pure cotton spunlace nonwoven fabric is used as the material for wrapping the heat pack, after water-repellent finishing, the average effective pore size inside the pure cotton spunlace nonwoven fabric increases, forming a continuous water-repellent film on the surface of the cotton fibers. The fibers adhere and bind more tightly, resulting in larger pores inside. At this time, the exudate from the wound is stored by the pure cotton spunlace nonwoven fabric, and the chemical heat pack is wrapped by the pure cotton spunlace nonwoven fabric. When the exudate drips into the heat pack, heat is generated. Furthermore, the magnesium sulfate skin-friendly hydrogel on the pure cotton spunlace nonwoven fabric directly adheres to the skin, and the hydrogel contains a large amount of skin-friendly substances, making it... The chemical heating pack is unlikely to cause stinging upon contact with the patient. Magnesium ions, upon entering the body, can inhibit platelet function and regulate coagulation. At low concentrations, it stimulates Na+, K+, and ATPases, while at high concentrations, it inhibits their activity, regulating transmembrane sodium and potassium movement. This downregulates inflammatory mediators, reduces inflammation, and heals bruising. Furthermore, the chemical heating pack maintains continuous heating based on the amount of exudate. The excellent insulation properties of the pure cotton spunlace nonwoven fabric enhance the pack's heat retention. The use of carbon powder within the pack accelerates the heating efficiency of the iron powder. At this temperature, the magnesium sulfate in the skin-friendly hydrogel can better penetrate the wound, reducing inflammation around the wound and promoting patient recovery. The magnesium sulfate skin-friendly hydrogel can be directly applied to the wound. Therefore, this invention maintains a stable temperature.

[0027] 2. In the preparation method and dressing of the blood-activating and stasis-removing dressing of the present invention, the pure cotton spunlace nonwoven fabric, after water-repellent finishing, becomes stiffer and has high air permeability, high rigidity and flexibility, and excellent skin-friendly properties; at the same time, combined with the good water-repellent effect of the flash-evaporated nonwoven fabric, it can prevent the test liquid from contacting the skin, allowing the pure cotton spunlace fabric to quickly absorb liquid and allow the liquid to diffuse inside, thus having a long-term water storage capacity, enabling the heat pack to release heat stably for a long time. Therefore, the heat pack of the present invention provides stable heat release for a long time and has good waterproof effect.

[0028] 3. In the preparation method and dressing of the present invention for promoting blood circulation and removing blood stasis, the hydrogel can absorb and fix several times or even hundreds of times its weight in water, forming a soft and moist gel-like substance. The hydrogel can retain moisture and has a certain degree of breathability, which helps maintain the normal respiration of the skin or tissue. The treatment using hydrogel dressings has a higher rate of reduction in total wound area and volume compared with traditional bandage treatment, and the effect is better. Therefore, the present invention has good breathability and good effect.

[0029] 4. In the preparation method and dressing of the blood-activating and stasis-removing dressing of this invention, the outermost layer of the dressing is made of flash-spun nonwoven fabric with fibers as fine as 0.11 dtex, high crystallinity, and good fiber orientation, resulting in high strength and excellent tear resistance, which is 2-3 times that of polypropylene nonwoven fabric produced by other methods. It is also less prone to pilling, does not attract dust, has good dimensional stability, good waterproof and breathable properties, and its strength at the same areal density is several times that of other spunbond products. Therefore, this invention has high strength and good waterproof and breathable properties. Attached Figure Description

[0030] Figure 1 It is a structural schematic diagram of the present invention.

[0031] Figure 2 This is a schematic diagram of the temperature change curve of the heating pack in this invention.

[0032] Figure 3 This is a diagram showing the heating rate of the heating pack in this invention. Detailed Implementation

[0033] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0034] See Figures 1 to 3 A method for preparing a blood-activating and stasis-removing dressing, the method comprising the following steps:

[0035] The first step is to evenly sprinkle EVAL powder onto PP spunbond fabric, and then laminate the side of the PP spunbond fabric with EVAL powder onto PE spunbond film to obtain SF film composite material.

[0036] The second step is to first make an open cloth bag from SF film composite material, then fill the cloth bag with an appropriate amount of iron powder and carbon powder and seal it to obtain a chemical heat pack. Then, the chemical heat pack is laminated into a pure cotton spunlace nonwoven fabric, and then a flash nonwoven fabric is laminated on top of the pure cotton spunlace nonwoven fabric.

[0037] The third step is to first prepare PVA solution and carboxymethyl chitosan solution separately, then take an appropriate amount of PVA solution and carboxymethyl chitosan solution and mix them evenly, then add an appropriate amount of magnesium sulfate solution and stir evenly. After standing, the mixture will solidify and form a skin-friendly hydrogel.

[0038] Step 4: Adhere the skin-friendly hydrogel to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and stasis-removing dressing.

[0039] In the first step, EVAL powder is first evenly sprinkled on PP spunbond fabric, and then the side of the PP spunbond fabric with EVAL powder is laminated with PE spunbond film to obtain SF film composite material. Specifically, EVAL powder is evenly sprinkled on the prepared PP spunbond fabric, and then the powder is melted by heating and introduced into the PE breathable membrane. Hot melt adhesive is impregnated on the surface of the two materials, and then pressure is applied using a laminating machine to solidify the hot melt adhesive in a short time, so that the PP spunbond fabric and PE breathable membrane are bonded together to become SF film composite material.

[0040] In the second step, the appropriate amount of iron powder and carbon powder is as follows: the mass percentage of iron powder to carbon powder is 5-20: carbon powder 1-10.

[0041] In the second step, the chemical heat pack is further laminated inside the pure cotton spunlace nonwoven fabric. Specifically, the upper layer is pure cotton spunlace nonwoven fabric, the middle layer is the chemical heat pack, and the lower layer is pure cotton spunlace nonwoven fabric. The upper and lower layers of pure cotton spunlace nonwoven fabric wrap the chemical heat pack inside.

[0042] The chemical heat pack has a heating rate of 8℃ / min to 14℃ / min, a temperature of 31℃ to 65℃, and a continuous heating time of 140 minutes to 201 minutes.

[0043] The pure cotton spunlace nonwoven fabric and the flash nonwoven fabric have the same length and width, but the length and width of the pure cotton spunlace nonwoven fabric are greater than those of the skin-friendly hydrogel.

[0044] Both the pure cotton spunlace nonwoven fabric and the flash-steamed nonwoven fabric are 15cm×15cm squares, and the magnesium sulfate skin-friendly hydrogel is a 5×5cm square.

[0045] In the third step, the mass fraction of the PVA solution is 5%–20%, the mass fraction of the carboxymethyl chitosan solution is 5%–20%, and the mass fraction of the magnesium sulfate solution is 10%–40%.

[0046] The volume ratio of the PVA solution, carboxymethyl chitosan solution, and magnesium sulfate solution is 2-15:2-15:0.1-1.

[0047] The PVA solution is prepared as follows: 5-15g of polyvinyl alcohol is placed in 40g of deionized water, heated and ultrasonically treated for 5min to obtain the PVA solution;

[0048] The preparation method of the carboxymethyl chitosan solution is as follows: then take 5-15g of carboxymethyl chitosan and place it in 40g of deionized water to obtain the carboxymethyl chitosan solution;

[0049] The magnesium sulfate solution is prepared as follows: 10-50g of magnesium sulfate is dissolved in warm water at 40℃ to obtain a magnesium sulfate solution;

[0050] The process of obtaining a skin-friendly hydrogel by cooling and solidifying after static conditions is as follows: magnesium sulfate solution is ultrasonically treated for 5 minutes, poured into a mold, and then cooled and solidified for 12 hours to obtain a skin-friendly hydrogel.

[0051] A blood-activating and stasis-removing dressing is prepared using the above-mentioned preparation method. The blood-activating and stasis-removing dressing includes a flash-evaporated nonwoven fabric, a pure cotton spunlace nonwoven fabric, a heat pack, and a skin-friendly hydrogel. The flash-evaporated nonwoven fabric is placed on top of the pure cotton spunlace nonwoven fabric, the heat pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is placed at the bottom of the pure cotton spunlace nonwoven fabric.

[0052] A blood-activating and stasis-removing dressing is prepared using the aforementioned method. The dressing comprises a flash-evaporated nonwoven fabric, a pure cotton spunlace nonwoven fabric, a heat pack, and a skin-friendly hydrogel. The flash-evaporated nonwoven fabric is positioned on top of the pure cotton spunlace nonwoven fabric, the heat pack is embedded within the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is positioned at the bottom of the pure cotton spunlace nonwoven fabric.

[0053] The following are supplementary descriptions of the present invention:

[0054] The dressing size can also be 20cm×20cm, 20cm×30cm, or 15cm×20cm, and can be used for partial and full-thickness skin injuries with exudate.

[0055] Example 1:

[0056] A method for preparing a blood-activating and stasis-removing dressing, the method comprising the following steps:

[0057] The first step is to evenly sprinkle EVAL powder onto PP spunbond fabric, and then laminate the side of the PP spunbond fabric with EVAL powder onto PE spunbond film to obtain SF film composite material. SF film is a waterproof and oil-proof film.

[0058] The second step is to first make an open cloth bag from the SF film composite material, then fill the bag with 5-20g of iron powder and 1-10g of carbon powder to obtain a chemical heat pack. After sealing the chemical heat pack, it is combined with pure cotton spunlace nonwoven fabric. Then, a layer of flash nonwoven fabric is combined on top of the pure cotton spunlace nonwoven fabric.

[0059] Step 3: First, take 5-15g of polyvinyl alcohol and place it in 40g of deionized water. After heating and ultrasonic treatment for 5 minutes, obtain a PVA solution for later use. Then, take 5-15g of carboxymethyl chitosan and place it in 40g of deionized water to obtain a carboxymethyl chitosan solution for later use. Next, take 10-50g of magnesium sulfate and dissolve it in 40℃ warm water to obtain a magnesium sulfate solution. Then, take 2-15ml of PVA solution and carboxymethyl chitosan solution and mix them evenly. Then, add 0.1-1ml of magnesium sulfate solution and ultrasonic treatment for 5 minutes. Pour the mixture into a mold and then let it cool for 12 hours to form a skin-friendly hydrogel.

[0060] Step 4: Adhere the skin-friendly hydrogel to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and stasis-removing dressing.

[0061] A blood-activating and stasis-removing dressing is prepared using the above-mentioned preparation method. The blood-activating and stasis-removing dressing includes a flash-evaporated nonwoven fabric, a pure cotton spunlace nonwoven fabric, a heat pack, and a skin-friendly hydrogel. The flash-evaporated nonwoven fabric is placed on top of the pure cotton spunlace nonwoven fabric, the heat pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is placed at the bottom of the pure cotton spunlace nonwoven fabric.

[0062] When applying: The hydrogel is mixed in a 1:1 ratio. Magnesium sulfate has anti-inflammatory properties and can help reduce inflammation around the wound. By reducing inflammation, magnesium sulfate helps reduce redness and pain around pressure sores, thus creating a more favorable environment for healing. The skin absorbs magnesium sulfate, which helps dilate blood vessels, increasing blood flow to the damaged area. Better blood circulation brings more oxygen and nutrients, which helps the wound repair and heal.

[0063] Example 2:

[0064] Example 2 is basically the same as Example 1, except that:

[0065] A method for preparing a blood-activating and stasis-removing dressing, the method comprising the following steps:

[0066] The first step is to evenly sprinkle EVAL powder onto the prepared PP spunbond fabric, then melt the powder by heating and introduce it into the PE breathable membrane. Hot melt adhesive is then applied to the surfaces of the two materials. The hot melt adhesive is then pressed using a laminating machine to cure the hot melt adhesive in a short time, thus bonding the PP spunbond fabric and the PE breathable membrane together to form an SF membrane composite material.

[0067] The second step is to first make an open cloth bag from the SF film composite material, then fill the bag with 10g of iron powder and 2g of carbon powder to obtain a chemical heat pack, then seal the chemical heat pack and combine it with pure cotton spunlace nonwoven fabric, and then combine a layer of flash nonwoven fabric on top of the pure cotton spunlace nonwoven fabric.

[0068] Step 3: First, take 10g of polyvinyl alcohol and place it in 40g of deionized water. After heating and ultrasonic treatment for 5 minutes, obtain a PVA solution for later use. Then, take 10g of carboxymethyl chitosan and place it in 40g of deionized water to obtain a carboxymethyl chitosan solution for later use. Next, take 30g of magnesium sulfate and dissolve it in 40℃ warm water to obtain a magnesium sulfate solution. Then, take 15ml of PVA solution and carboxymethyl chitosan solution and mix them evenly. Then, add 0.5ml of magnesium sulfate solution and ultrasonic treatment for 5 minutes. Pour the mixture into a mold and then let it cool for 12 hours to form a skin-friendly hydrogel.

[0069] Step 4: Adhere the skin-friendly hydrogel to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and stasis-removing dressing.

[0070] In application: a ratio of 10g iron powder to 2g carbon powder results in a specific heat capacity of 460J / (kg·℃) for the reduced iron powder, slightly lower than the specific heat capacity of 840J / (kg·℃) for activated carbon. The higher the content of reduced iron powder in the mixed powder, the lower the overall specific heat capacity of the chemical heating agent, and the less heat is required to raise the mixed powder to the same temperature, thus making it easier to heat up. Using "10ml, 10% PVA solution, 10% carboxymethyl chitosan solution, 0.5ml, 30% magnesium sulfate solution, 12h molding" results in rapid molding, minimal precipitation, and commonly produces pressure sores with an area of ​​approximately 4cm². 2 By selecting the above values, the area to be made can completely cover the wound, minimizing material waste.

[0071] Example 3:

[0072] Example 3 is basically the same as Example 1, except that:

[0073] like Figures 2 to 3 As shown, the chemical heating pack rapidly heated to 51℃ within 15 minutes at an average heating rate of 2.3℃ / min. The real-time heating rate decreased continuously over time, and the temperature remained between 51℃ and 52℃ for 38 minutes, during which the heating rate was approximately 0℃ / min. The chemical heating pack then began to cool down, gradually decreasing to room temperature with a negative heating rate, initially increasing in absolute value and then decreasing to near zero. The process of sealing the chemical heating pack and then combining it with a pure cotton spunlace nonwoven fabric is as follows: the upper layer is pure cotton spunlace nonwoven fabric, the middle layer is the chemical heating pack, and the lower layer is pure cotton spunlace nonwoven fabric. The upper and lower layers of pure cotton spunlace nonwoven fabric encapsulate the chemical heating pack. 10.0g of iron powder and 2.0g of carbon powder were mechanically perforated and sealed at room temperature, with an average heating rate of 10.1℃ / min, reaching a temperature of 45.6℃, and a continuous heating time of 186 minutes.

[0074] When applying: The chemical heat pack reaches the appropriate temperature in 4 minutes, the heating rate is 10.1℃ / min, and the heating duration is 186 minutes. After the heating efficiency reaction is complete, the texture changes from a granular feel to a powdery feel, which can be used to identify whether the reaction is complete. This design is to meet the current routine care needs of 4 to 5 times a day, with a heat compress duration of 3 hours. It can maintain the normal heat compress temperature and ensure the heat compress time. The heat compress temperature is controlled at 40-50℃, which is more conducive to recovery.

[0075] Example 4:

[0076] Example 4 is basically the same as Example 1, except that:

[0077] A blood-activating and stasis-removing dressing is prepared using the aforementioned preparation method. The dressing comprises a flash-evaporated nonwoven fabric, a pure cotton spunlace nonwoven fabric, a heat pack, and a skin-friendly hydrogel. The flash-evaporated nonwoven fabric is placed on top of the pure cotton spunlace nonwoven fabric, and the heat pack is embedded within it. The heat pack is made of PP, PE, and EVAL, with the addition of a pore-forming agent CaCO3 followed by mechanical stretching to control the pore structure, ensuring timely and quantitative dripping of exudate and guaranteeing stable heat release over a long period. The skin-friendly hydrogel is placed at the bottom of the pure cotton spunlace nonwoven fabric. The pure cotton spunlace nonwoven fabric and the flash-evaporated nonwoven fabric have the same length and width, but the length and width of the pure cotton spunlace nonwoven fabric are greater than those of the skin-friendly hydrogel. The pure cotton spunlace nonwoven fabric and the flash-evaporated nonwoven fabric are 15cm × 15cm squares, and the magnesium sulfate skin-friendly hydrogel is a 5×5cm square.

[0078] In application: Pure cotton spunlace nonwoven fabric is degreased. During the degreasing process, impurities such as fat and wax in the cotton are removed, making the surface of the cotton fibers cleaner and smoother. This allows water to penetrate more easily into the fiber interior, thereby increasing the water absorption of the cotton fibers and making them more suitable for textiles and other applications requiring good water absorption. The chemical structure of cotton fibers contains a large number of polar groups (such as hydroxyl groups), which can form hydrogen bonds with water molecules, thus giving cotton fibers good hydrophilicity and hygroscopicity. Spunlace nonwoven fabric is a material composed of a porous structure formed by the three-dimensional random arrangement of fibers. It has a large specific surface area and many capillary channels, which is conducive to the adsorption and transport of water molecules. At the same time, due to the large number of gaps and channels between fibers, water molecules can quickly diffuse into the interior of the fiber web, thereby improving the overall hygroscopic performance.

[0079] Example 5:

[0080] Example 5 is basically the same as Example 1, except that:

[0081] The bottom of the pure cotton spunlace nonwoven fabric is surrounded by a ring-shaped strap on the outside of the skin-friendly hydrogel, which is used to fix the dressing to the wrist or ankle.

[0082] Example 6:

[0083] Example 6 is basically the same as Example 1, except that:

[0084] The severity grading (n / %) of phlebitis after treatment with magnesium sulfate skin-friendly hydrogel is shown in the table below.

[0085]

[0086] The following table shows a comparison of the incidence (n / %) of adverse reactions after using magnesium sulfate hydrogel.

[0087]

[0088] The table below shows a comparison of patients' pain levels (n / %) 30 minutes after applying the blood-activating and stasis-removing dressing.

[0089]

[0090] The comparison of wound healing rates (n / %) between the two groups is shown in the table below.

[0091]

[0092] The data comparison in the table above shows that dressings made with this product effectively improve wound healing and reduce patient pain.

[0093] The above description is only a preferred embodiment of the present invention. The scope of protection of the present invention is not limited to the above embodiments. Any equivalent modifications or changes made by those skilled in the art based on the content disclosed in the present invention should be included within the scope of protection set forth in the claims.

Claims

1. A method for preparing a blood-activating and stasis-removing dressing, characterized in that: The preparation method of the blood-activating and stasis-removing dressing includes the following steps: The first step is to evenly sprinkle EVAL powder onto PP spunbond fabric, and then laminate the side of the PP spunbond fabric with EVAL powder onto PE spunbond film to obtain SF film composite material. The second step is to first make an open cloth bag from SF film composite material, then fill the cloth bag with an appropriate amount of iron powder and carbon powder and seal it to obtain a chemical heat pack. Then, the chemical heat pack is laminated into a pure cotton spunlace nonwoven fabric, and then a flash nonwoven fabric is laminated on top of the pure cotton spunlace nonwoven fabric. The third step is to first prepare PVA solution and carboxymethyl chitosan solution separately, then take an appropriate amount of PVA solution and carboxymethyl chitosan solution and mix them evenly, then add an appropriate amount of magnesium sulfate solution and stir evenly. After standing, the mixture will solidify and form a skin-friendly hydrogel. Step 4: Adhere the skin-friendly hydrogel to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and stasis-removing dressing.

2. The method for preparing a blood-activating and stasis-removing dressing according to claim 1, characterized in that: The process involves first uniformly sprinkling EVAL powder onto PP spunbond fabric, and then laminating the side of the PP spunbond fabric with EVAL powder onto a PE spunbond membrane to obtain an SF membrane composite material. Specifically, EVAL powder is uniformly sprinkled onto the prepared PP spunbond fabric, then the powder is melted by heating and introduced into the PE breathable membrane. Hot melt adhesive is applied to the surfaces of the two materials, and then pressure is applied using a laminating machine to cure the hot melt adhesive in a short time, thereby bonding the PP spunbond fabric and the PE breathable membrane together to form an SF membrane composite material.

3. The method for preparing a blood-activating and stasis-removing dressing according to claim 1, characterized in that: In the second step, the appropriate amount of iron powder and carbon powder is as follows: the mass percentage of iron powder to carbon powder is 5-20: carbon powder 1-10.

4. The method for preparing a blood-activating and stasis-removing dressing according to claim 2, characterized in that: In the second step, the chemical heat pack is further laminated inside the pure cotton spunlace nonwoven fabric. Specifically, the upper layer is pure cotton spunlace nonwoven fabric, the middle layer is the chemical heat pack, and the lower layer is pure cotton spunlace nonwoven fabric. The upper and lower layers of pure cotton spunlace nonwoven fabric wrap the chemical heat pack inside.

5. The method for preparing a blood-activating and stasis-removing dressing according to claim 3, characterized in that: The chemical heat pack has a heating rate of 8℃ / min to 14℃ / min, a temperature of 31℃ to 65℃, and a continuous heating time of 140 minutes to 201 minutes.

6. The method for preparing a blood-activating and stasis-removing dressing according to claim 1, characterized in that: The pure cotton spunlace nonwoven fabric and the flash nonwoven fabric have the same length and width, but the length and width of the pure cotton spunlace nonwoven fabric are greater than those of the skin-friendly hydrogel.

7. The method for preparing a blood-activating and stasis-removing dressing according to claim 6, characterized in that: Both the pure cotton spunlace nonwoven fabric and the flash-steamed nonwoven fabric are 15cm×15cm squares, and the magnesium sulfate skin-friendly hydrogel is a 5×5cm square.

8. The method for preparing a blood-activating and stasis-removing dressing according to claim 1, characterized in that: In the third step, the mass fraction of the PVA solution is 5%–20%, the mass fraction of the carboxymethyl chitosan solution is 5%–20%, and the mass fraction of the magnesium sulfate solution is 10%–40%. The volume ratio of the PVA solution, carboxymethyl chitosan solution, and magnesium sulfate solution is 2-15:2-15:0.1-1.

9. The method for preparing a blood-activating and stasis-removing dressing according to claim 8, characterized in that: The PVA solution is prepared as follows: 5-15g of polyvinyl alcohol is placed in 40g of deionized water, heated and ultrasonically treated for 5min to obtain the PVA solution; The preparation method of the carboxymethyl chitosan solution is as follows: then take 5-15g of carboxymethyl chitosan and place it in 40g of deionized water to obtain the carboxymethyl chitosan solution; The magnesium sulfate solution is prepared as follows: 10-50g of magnesium sulfate is dissolved in warm water at 40℃ to obtain a magnesium sulfate solution; The process of obtaining a skin-friendly hydrogel by cooling and solidifying after static conditions is as follows: magnesium sulfate solution is ultrasonically treated for 5 minutes, poured into a mold, and then cooled and solidified for 12 hours to obtain a skin-friendly hydrogel.

10. A blood-activating and stasis-removing dressing, characterized in that: The blood-activating and stasis-removing dressing is prepared using the preparation method of the blood-activating and stasis-removing dressing according to claim 1. The blood-activating and stasis-removing dressing includes a flash-steamed nonwoven fabric, a pure cotton spunlace nonwoven fabric, a hot compress pack, and a skin-friendly hydrogel. The flash-steamed nonwoven fabric is placed on top of the pure cotton spunlace nonwoven fabric, the hot compress pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is placed at the bottom of the pure cotton spunlace nonwoven fabric.

Images