A Chinese medicine composition for pediatric spleen and stomach plaster and its preparation method

Abstract

The present invention belongs to the field of traditional Chinese medicine technology and discloses a pediatric spleen and stomach plaster Chinese medicine composition and preparation method thereof. The key points of the technical solution are that the Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: Linderae Root, Patchouli Radix, Citrus Aurantii Rhizoma, Atractylodes Macrocephalae, and Corydalis Rhizoma. The spleen and stomach plaster provided by the present invention applies a medicine with warming and tonic properties to the corresponding acupuncture points. Through the stimulating effect of the medicine itself, the skin penetration effect, and the meridian properties of the acupuncture points, the overall function of the human internal organs is regulated to achieve the purpose of treatment. It has a good therapeutic effect on anorexia, abdominal pain, constipation, vomiting, and other symptoms caused by spleen and stomach deficiency and cold, and is suitable for children of all ages.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicines, and more particularly to a pediatric spleen and stomach plaster traditional Chinese medicine composition and a preparation method thereof. Background Art

[0002] Spleen and stomach deficiency and coldness refer to symptoms manifested by a deficiency of spleen and stomach yang qi and an internal accumulation of yin and cold. This includes both spleen yang deficiency and stomach yang deficiency (some believe it refers solely to spleen yang deficiency), often caused by dietary imbalances, excessive consumption of raw and cold foods, overwork, prolonged illness, or anxiety that damages the spleen. Symptoms of spleen yang deficiency include poor appetite, abdominal distension, epigastric pain that responds to warmth and pressure, a bland mouth without thirst, cold extremities, loose stools or edema, aversion to cold and preference for warmth, clear, long, or difficult urination, and, in women, thin, profuse vaginal discharge, a pale, plump, tender tongue with a white, moist coating, and a deep, slow pulse. Pain in stomach yang deficiency is often triggered by cold weather or exposure to cold foods. The pain is accompanied by a chill in the stomach, which is alleviated by warmth. The stomachache is dull, persistent, and uncomfortable, with a preference for warmth and pressure. The pain is worse on an empty stomach and relieved by food. The pain flares up or worsens after exertion, cold food, or exposure to cold. There is vomiting of clear water, poor appetite, fatigue, cold hands and feet, loose, thin stools, a pale tongue with a white coating, and a weak pulse. Stomach Yang deficiency syndrome is diagnosed based on symptoms of disharmony and descent of the stomach and the manifestations of Yang deficiency. Spleen Yang deficiency syndrome is diagnosed based on symptoms of spleen deficiency and cold. Spleen and stomach deficiency and cold can easily lead to symptoms such as anorexia, abdominal pain, constipation, and vomiting. These symptoms not only affect a child's absorption of nutrients and growth and development, but can also lead to shock and death in severe cases. Numerous medications are available on the market for treating spleen and stomach deficiency and cold in children, including both Western and Traditional Chinese Medicines. Western medicines have significant side effects, while Traditional Chinese Medicines have an even more unpleasant odor. Medication has certain side effects, and feeding children medications is also a challenge.

[0003] Therefore, the present invention provides a Chinese medicine composition for a pediatric spleen and stomach plaster and a preparation method thereof. Summary of the Invention

[0004] The purpose of the present invention is to provide a pediatric spleen and stomach plaster Chinese medicine composition.

[0005] In order to achieve the above object, the technical solution adopted by the present invention is:

[0006] A pediatric spleen and stomach plaster traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 80-120g of Linderae umbellatae, 80-120g of Patchouli, 80-120g of Citrus aurantium, 80-120g of Atractylodes macrocephala, and 80-120g of Corydalis yanhusuo.

[0007] Preferably, the Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 90-110g of Linderae scutellariae, 90-110g of Patchouli, 90-110g of Citrus aurantium, 90-110g of Atractylodes macrocephala, 90-110g of Corydalis yanhusuo

[0008] Preferably, the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 100g of Linderae strychnifolia, 100g of Patchouli strychnifolia, 100g of Citrus aurantium, 100g of Atractylodes macrocephala, and 100g of Corydalis yanhusuo.

[0009] Another object of the present invention is to provide a method for preparing the above-mentioned Chinese medicine composition.

[0010] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0011] S1: Grind the prescribed amounts of Linderae Root, Patchouli Radix Atractylodes, Citrus Aurantii Rhizoma, Atractylodes Rhizoma, and Rhizoma Corydalis into powder to obtain medicinal powder;

[0012] S2: adding the medicinal powder to a suitable matrix, stirring evenly until the mixture becomes a paste, thereby obtaining a paste of the traditional Chinese medicine composition;

[0013] S3: The paste of the traditional Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0014] Preferably, in step S1, the medicinal powder is an extremely fine powder.

[0015] Ultrafine powder refers to powder that can pass through the No. 8 sieve and contains no less than 95% of the powder that can pass through the No. 9 sieve; the mesh number of the No. 8 sieve is 150 mesh, and the mesh number of the No. 9 sieve is 200 mesh.

[0016] Preferably, in step S2, the matrix is ​​any one or more of rubber, thermoplastic rubber, rosin, rosin derivatives, vaseline, lanolin and zinc oxide.

[0017] Preferably, the matrix is ​​petrolatum.

[0018] Preferably, the mass ratio of the medicinal powder to the matrix is ​​1:1.

[0019] Another object of the present invention is to provide the use of the above-mentioned pediatric spleen and stomach plaster Chinese medicine composition in the preparation of a medicine for treating anorexia, abdominal pain, constipation or vomiting caused by spleen and stomach deficiency and cold.

[0020] It should be noted that the pharmacological effects of some of the raw materials in the formula of the present invention are as follows:

[0021] Linderae serrata: Linderae serrata Aggregate boundary(Sims)Kos-term. Dried root tuber. Nature and Meridian Pathogenesis: Pungent, warm. Enters the Lung, Spleen, Kidney, and Bladder meridians. Functions and Indications: Promotes qi and relieves pain, warms the kidneys and dispels cold. Used for cold-stagnation qi stagnation, chest and abdominal pain, qi reversal and shortness of breath, bladder deficiency and coldness, enuresis and frequent urination, hernia pain, and abdominal pain caused by cold menstruation.

[0022] Patchouli: Patchouli of the Lamiaceae family Rugged Agastache(Fisch.et Mey.)Q.Ktze.The whole plant or aerial parts of this herb. Nature and Meridians: Slightly warm, pungent. It enters the Lung, Spleen, and Stomach meridians. Functions and Indications: Aromatically eliminates dampness, soothes the stomach and stops vomiting, and dispels summer heat and relieves exterior symptoms. It treats dampness blocking the middle burner, causing abdominal distension and pain, loss of appetite, vomiting, diarrhea, headaches caused by exogenous summer heat and dampness, fever and fatigue at the onset of damp-heat, chest discomfort and nausea, sinusitis, and tinea pedis and manuum.

[0023] Green peel: for the Rutaceae plant citrus Citrus reticulate White The dried young or immature fruit peel of its cultivated varieties. Nature and flavor: bitter, pungent, warm. It enters the Liver, Gallbladder, and Stomach meridians. Functions and indications: Relieves exterior symptoms and dispels cold, dispels wind and relieves pain, clears the nasal passages, dries dampness and stops leukorrhea, reduces swelling and discharges pus. Soothes the liver and resolves qi, dissipates stagnation, and resolves stagnation. It is used for chest and flank pain, hernia pain, breast lumps, breast abscesses, food stagnation and qi stagnation, and abdominal distension and pain.

[0024] Raw Atractylodes macrocephala: Atractylodes macrocephala Atractylodes macrocephala Koidz. Dried rhizome. Nature and Meridian Pathogenesis: Bitter, sweet, warm. Enters the spleen and stomach meridians. Functions and Indications: Strengthens the spleen and replenishes qi, eliminates dampness and promotes diuresis, stops sweating, and stabilizes the fetus. Used for spleen deficiency, poor appetite, abdominal distension and diarrhea, phlegm and fluid retention, dizziness and palpitations, edema, spontaneous sweating, and fetal restlessness.

[0025] Yuanhu: is the plant of the Poppy family Corydalis yanhusuo Corydalis introduced WTWang Dried tuber of . Nature and flavor and meridians: pungent, bitter, warm. Enter the liver and spleen meridians. Functions and indications: promote blood circulation, promote qi circulation, and relieve pain. Used for chest and flank pain, epigastric pain, chest pain and heart pain, amenorrhea and dysmenorrhea, postpartum blood stasis, and swelling and pain caused by falls. It should also be noted that the method of use of the spleen and stomach plaster prepared by the present invention is: apply 1 patch per day to the patient's Zhongwan, Shenque or Tianshu acupoints, and 5 days is one course of treatment. Among them, Zhongwan warms the stomach and dispels cold, Shenque warms the spleen and relieves pain, and the bilateral Tianshu regulates the spleen and stomach, so that the spleen's ascending and stomach's descending functions are normal, then the spleen and stomach are healthy and diseases are not generated.

[0026] The present invention has the following beneficial effects:

[0027] 1. In the Chinese medicine composition of the present invention, Linderae Root warms and nourishes the spleen and kidney, Patchouli Radix is ​​aromatic and removes turbidity, Citrus aurantium peel promotes qi and eliminates stagnation, and Corydalis yanhusuo regulates qi and relieves pain and enters the blood. All the medicines are used together to warm the spleen and stomach, regulate qi and relieve pain.

[0028] 2. The spleen and stomach patch of this invention applies a warming and nourishing drug to the corresponding acupuncture points. Through the drug's own stimulation, skin penetration, and the meridian properties of the acupuncture points, it regulates the overall function of the human internal organs to achieve the therapeutic purpose. It has a good therapeutic effect on anorexia, abdominal pain, constipation, vomiting, and other symptoms caused by spleen and stomach deficiency and cold, and is suitable for children of all ages. DETAILED DESCRIPTION

[0029] In order to enable those skilled in the art to better understand the present invention, the technical solution of the present invention will be further described in detail below in conjunction with the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts should fall within the scope of protection of the present invention.

[0030] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments of the present invention can be combined with each other. The present invention will be described in detail below with reference to the embodiments.

[0031] Example 1:

[0032] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0033] S1: Grind 100g of Linderae scutellariae, 100g of Patchouli, 100g of Citrus aurantium, 100g of Atractylodes macrocephala, and 100g of Corydalis yanhusuo into very fine powder to obtain medicinal powder;

[0034] S2: adding the medicinal powder to an equal amount of vaseline, stirring evenly until the mixture becomes a paste, thereby obtaining a paste of the Chinese medicine composition;

[0035] S3: The paste of the traditional Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0036] Example 2:

[0037] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0038] S1: Grind 80g of Linderae Root, 80g of Patchouli Radix, 80g of Citrus Aurantii Radix, 120g of Atractylodes Macrocephala, and 120g of Corydalis Rhizoma into very fine powder to obtain medicinal powder;

[0039] S2: adding the medicinal powder to an equal amount of lanolin, stirring evenly until the mixture becomes a paste, thereby obtaining a paste of the Chinese medicine composition;

[0040] S3: The paste of the traditional Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0041] Example 3:

[0042] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0043] S1: Grind 120g of Linderae sibiricum, 120g of Patchouli, 80g of Citrus aurantium, 80g of Atractylodes macrocephala, and 80g of Corydalis yanhusuo into very fine powder to obtain medicinal powder;

[0044] S2: adding the medicinal powder to an equal amount of the rosin derivative, stirring evenly until the mixture becomes a paste, thereby obtaining a paste of the Chinese medicine composition;

[0045] S3: The paste of the traditional Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0046] Example 4:

[0047] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0048] S1: Grind 110g of Linderae sibiricum, 90g of Patchouli Radix Adenophorae, 110g of Citrus aurantium, 90g of Atractylodes macrocephala, and 90g of Corydalis yanhusuo into very fine powder to obtain medicinal powder;

[0049] S2: adding the medicinal powder to an equal mass of thermoplastic rubber, stirring evenly until the mixture becomes a paste, thereby obtaining a paste of the Chinese medicine composition;

[0050] S3: The paste of the traditional Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0051] Embodiment 5:

[0052] A method for preparing a pediatric spleen and stomach plaster Chinese medicine composition comprises the following steps:

[0053] S1: Grind 90g of Linderae Root, 90g of Patchouli Radix, 90g of Citrus Aurantii Radix, 110g of Atractylodes Macrocephala, and 110g of Corydalis Rhizoma into very fine powder to obtain medicinal powder;

[0054] S2: adding the medicinal powder to an equal amount of vaseline, stirring evenly until the mixture becomes a paste, thereby obtaining a paste of the Chinese medicine composition;

[0055] S3: The paste of the traditional Chinese medicine composition is made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a spleen and stomach plaster.

[0056] Clinical trial cases:

[0057] To prove that the spleen and stomach plaster prepared from the Chinese herbal composition of the present invention has the positive effects of dispelling exogenous pathogens and promoting the descending of lung qi, the inventors conducted a large number of clinical trials on the spleen and stomach plaster prepared in Example 1, and now select some clinical trials to report as follows.

[0058] Case 1: Mr. Li, a 2-year-9-month-old male, had been experiencing abdominal pain for the past month, primarily in the left lower abdomen, with dry stools and bowel movements every 2-3 days. He was given a spleen and stomach plaster applied to the Shenque and Tianshu acupoints. After one course of treatment, his symptoms were relieved.

[0059] Case 2: Xu, a 2-year-9-month-old female, had experienced intermittent abdominal pain for a week, primarily around the umbilicus. Abdominal ultrasound revealed enlarged mesenteric lymph nodes, but no other abnormalities were noted. Intermittent oral treatment with belladonna tablets and Lactobacillus acidophilus tablets was ineffective. A course of Spleen and Stomach Plaster applied to the Shenque and Tianshu acupoints resolved the abdominal pain.

[0060] Case 3: Qu Moumou, female, 10 years and 11 months old, developed vomiting symptoms 2 days ago due to careless diet. The vomitus was undigested gastric contents, 2-3 times a day, not in a jet-like state. She was given a spleen and stomach plaster applied to Zhongwan, Shenque, and Tianshu, 2-4 hours / time, once a day, for a total of 2 days, and the symptoms were relieved.

[0061] Case 4: Cui Moumou, male, 4 years and 7 months old, had loose stools with increased frequency for more than a month. The child had loose stools for more than a month, 3-4 times / day, without mucus, pus or blood. He was treated with oral probiotics and montmorillonite powder, but the effect was not good. He was given 2 courses of spleen and stomach plaster on Shenque and Tianshu points, and the symptoms were relieved.

[0062] Case 5: Sha Moumou, male, 5 years and 9 months old, usually had dry stool and irregular bowel movements, with bowel movements once every 3-5 days. Intermittent oral probiotic treatment had poor efficacy. He was given a spleen and stomach plaster applied to the Tianshu acupoint for 2 courses of treatment, and his stool became soft, with bowel movements once every 1-2 days.

[0063] Case 6: Yu Moumou, male, 3 years and 4 months old, had abdominal pain for more than half a year, mainly in the upper abdomen, accompanied by nausea and vomiting. Electronic gastroscopy showed gastritis. He took medication regularly, but still had intermittent abdominal pain. He applied spleen and stomach plaster on Zhongwan, Tianshu and Guanyuan acupoints. After 4 courses of treatment, the pain was relieved.

[0064] Case 7: Liu Moumou, female, 3 years and 2 months old, had intermittent abdominal pain for more than a month, mainly around the umbilicus, without nausea and vomiting. She was given a course of Piwei patch on Shenque and Tianshu acupoints, and the pain was relieved.

[0065] Case 8: Zhao, a 4-year-old female, had been experiencing poor appetite for a year, with no abdominal pain, bloating, nausea, or vomiting, and normal bowel movements. She was given a Piwei plaster applied to the Zhongwan, Shenque, and Tianshu acupoints for two courses, and her appetite improved.

[0066] Case 9: Guo Moumou, male, 12 years and 5 months old, had diarrhea 2 weeks ago and was treated with oral montmorillonite powder, probiotics and other drugs. Later, he developed dry stools and defecated once every 3-4 days. He was given a course of spleen and stomach plaster and his constipation symptoms improved.

[0067] Case 10: Liu Moumou, female, 6 years and 6 months old, had intermittent abdominal pain for more than half a month, with no fixed tenderness in the whole abdomen. Abdominal ultrasound showed no obvious abnormalities. She was given 2 courses of spleen and stomach plaster and her symptoms were relieved.

[0068] In summary, the spleen and stomach plaster prepared by the present invention has the functions of warming the spleen and stomach, regulating qi and relieving pain, and has the efficacy and the like, and is mainly used to treat anorexia, abdominal pain, diarrhea, constipation, vomiting and the like.

[0069] This specific embodiment is merely an explanation of the present invention and is not intended to limit the present invention. After reading this specification, those skilled in the art may make non-creative modifications to this embodiment as needed. However, as long as such modifications are within the scope of the claims of the present invention, they are protected by patent law.

Claims

1. A pediatric spleen and stomach plaster, characterized in that: The plaster is composed of the following raw medicinal materials in parts by weight: 80-120g of Linderae strychnifolia, 80-120g of Patchouli, 80-120g of Citrus aurantium, 80-120g of Atractylodes macrocephala, and 80-120g of Corydalis yanhusuo.

2. A pediatric spleen and stomach plaster according to claim 1, characterized in that The plaster is composed of the following raw medicinal materials in parts by weight: 90-110g of Linderae strychnifolia, 90-110g of Patchouli, 90-110g of Citrus aurantium, 90-110g of Atractylodes macrocephala, and 90-110g of Corydalis yanhusuo.

3. A pediatric spleen and stomach plaster according to claim 2, characterized in that, The plaster is composed of the following raw medicinal materials in parts by weight: 100g of Linderae striata, 100g of Patchouli, 100g of Citrus aurantium, 100g of Atractylodes macrocephala, and 100g of Corydalis yanhusuo.

4. A method for preparing the pediatric spleen and stomach plaster according to any one of claims 1 to 3, characterized in that: The steps include: S1: Grind the prescribed amounts of Linderae Root, Patchouli Radix Atractylodes, Citrus Aurantii Rhizoma, Atractylodes Rhizoma, and Rhizoma Corydalis into powder to obtain medicinal powder; S2: adding the drug powder to the matrix in a mass ratio of 1:1, stirring evenly until the mixture becomes a paste, to obtain a paste; S3: The paste was made into a medicine cake with a diameter of 3 cm and a thickness of 0.5 cm, and placed in a blank non-woven plaster to obtain a pediatric spleen and stomach plaster.

5. The preparation method of the pediatric spleen and stomach plaster according to claim 4, characterized in that, In step S1, the medicinal powder is an extremely fine powder.

6. The preparation method of the pediatric spleen and stomach plaster according to claim 4, characterized in that: In step S2, the matrix is ​​any one or more of rubber, thermoplastic rubber, rosin, rosin derivatives, vaseline and lanolin.

7. The preparation method of the pediatric spleen and stomach plaster according to claim 4, characterized in that: The matrix is ​​vaseline.

8. Use of the pediatric spleen and stomach patch according to any one of claims 1 to 3 in the preparation of a medicine for treating anorexia, abdominal pain, constipation or vomiting caused by spleen and stomach deficiency and cold.