Agricultural preparation containing nicotine or bisamide compounds

Abstract

The invention belongs to the field of insecticides, and relates to an agricultural preparation containing nicotine or bisamide compounds. The preparation consists of an active component, a surfactant and a functional aid, wherein the active component accounts for 0.2-60% of the mass of the preparation, and the active component is a nicotine compound or a bisamide compound. According to the present invention, the lignin auxiliary agent and the starch are subjected to compatibility use, such that the excellent adhesion ability improving effect can be provided under the appropriate ratio, the lignin yield is only second to the cellulose yield, the lignin is the most abundant aromatic compound capable of being obtained from the renewable resources, the production capacity is outstanding throughout the world, and the non-toxic and cheap effects are provided.

Description

Technical Field

[0001] The invention belongs to the field of pesticides and relates to an agricultural preparation containing nicotine or diamide compounds. Background Art

[0002] There are many types of underground pests, which are serious and widely distributed. They are one of the important disasters in agricultural production. There are many types of crops that are harmed. The main underground pests are cutworms, white grubs, wireworms, mole crickets, etc. They usually feed on plant roots, stems and leaves before sowing or during the growth of crops, causing damage to seedlings; they bite off seedlings during the growth of crops, causing the plants to die; and they harm seeds and fruits after the harvest of crops. Underground pests not only harm the seeds, seedlings, and rhizomes of crops, but also cause missing seedlings and broken ridges. According to statistics, the economic losses caused by underground pests in the country amount to 10 billion yuan each year. Therefore, prevention and control of underground pests is an important measure to ensure high and stable crop yields.

[0003] Nicotinoid compounds are key agents for underground pest control. Currently, the nicotinoid compounds used for underground pest control in China are mainly imidacloprid, thiamethoxam, clothianidin and dinotefuran, among which imidacloprid, thiamethoxam and clothianidin are mainly used. The mechanism of action of nicotinoid insecticides is that they selectively bind to acetylcholine receptors as nicotinic acetylcholine receptor agonists, compete with insect acetylcholine, block the normal conduction of the central nervous system, and then cause insect paralysis and death. But nicotine The high solubility of these compounds in water has long been a drawback for the application of seed coating agents. After the seeds are coated, they are easily lost with rainwater, which brings safety problems.

[0004] Because underground pests live and cause harm underground and are hidden, prevention and control should follow the principle of prevention first and comprehensive prevention and control. For prevention, the most effective way is chemical control. Chemical control generally adopts two methods. One is to mix seeds with chemicals, that is, to use seed treatment agent technology, prepare the liquid medicine according to the requirements, mix it with seeds, and dry it completely before sowing, which can effectively prevent and control underground pests; the other is soil treatment, which is to use granules containing active ingredients before sowing, mix the soil, ensure that it is evenly spread on the ground, and after part of it is adsorbed in the soil, sow it.

[0005] For both methods of underground pest control, there are problems with the adhesion ability and adhesion degree of the agents. Whether it is the application of the agent attached to the seeds as seed dressing, or the application of mixing around the soil particles and adsorbing it in the soil as much as possible, it is necessary to effectively improve the adhesion degree of the agent. The current method of improving the adhesion degree basically adopts the method of film-forming substances or high molecular polymers in the formulation, but the actual effect of improving the adhesion ability and the environmental problems caused by residues in the soil need to be effectively solved.

[0006] This problem has always existed as a difficult problem in the industry and needs to be studied and solved. Summary of the invention

[0007] The object of the present invention is to provide an agricultural preparation containing nicotine or bisamide compounds.

[0008] To achieve the above purpose, the present invention adopts the following technical solution:

[0009] An agricultural preparation containing nicotine or bisamide compounds, the preparation is composed of active ingredients, surfactants and functional additives; wherein the active ingredients account for 0.2-60% of the preparation mass, and the active ingredients are nicotine compounds or bisamide compounds.

[0010] The functional additive is corn starch and / or potato starch.

[0011] The surfactant is selected from one or more of fatty alcohol polyoxyethylene ether, polyoxyethylene polyoxypropylene ether block copolymer, sorbitan fatty acid ester polyoxyethylene ether, and lignin sulfonate.

[0012] Furthermore, the surfactant is selected from one or more of lignin sulfonate, polymer carboxylate, naphthalene sulfonate, naphthalene sulfonate formaldehyde condensate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfonate, sodium dodecylbenzene sulfonate, sodium dodecyl sulfate, fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, polyoxyethylene polyoxypropylene ether block copolymer, and sorbitan fatty acid ester polyoxyethylene ether; for example, including but not limited to YUS-FS3000, Ultrazine NA, AEO-5, 127FL, Tween-80, Borresperse NA, etc.

[0013] Preferably, the surfactant is selected from lignin sulfonates; for example Ultrazine NA, Borresperse NA.

[0014] The mass ratio of the active ingredient to the remaining components (total mass of surfactants and functional additives) is 10:1-1:1; the mass ratio of surfactants to functional additives is 2:1-3:1;

[0015] The nicotine compound is one or more of imidacloprid, thiamethoxam and clothianidin; the diamide compound is compound A;

[0016]

[0017] Compound A.

[0018] The formulation type can be a seed treatment suspension, a seed treatment emulsion, a seed treatment dry powder, a seed treatment microcapsule suspension, or a granule.

[0019] The preparation may also contain other adjuvants, such as:

[0020] The carrier is selected from one or more of water, S150#, clay, diatomaceous earth, bentonite, magnesium aluminum silicate, white carbon black, light calcium carbonate and carbon dioxide.

[0021] Thickening substances may also be included, which may be one or more of xanthan gum, gelatin, gum arabic, polyvinyl acetate, polyvinyl pyrrolidone, magnesium aluminum silicate, polyethylene glycol, phenolic resin, sodium polyacrylate, polyurea prepolymer, styrene maleic anhydride copolymer, shellac, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, methyl cellulose and sodium alginate, which may improve the stability of the preparation to a certain extent.

[0022] If required by the application, a defoaming agent may be added. The defoaming agent may be one or more of SAG1522, silicones, C8-10 fatty alcohols, phosphates, C10-20 saturated fatty acids (such as capric acid) and amides or others.

[0023] If it is necessary to store it for a long time, a preservative may be added, which may be one or more of sodium benzoate, kason (2-methyl-4-isothiazoline-3-one and (B) 5-chloro-2-methyl-4-isothiazoline-3-one), potassium sorbate, sodium dehydroacetate or others.

[0024] If you need to adjust the pH of the system, you can also add hydrochloric acid, sodium hydroxide, etc.

[0025] If color is required, color-alerting agents may be added, which may include dyes, pigments (including toners and color pastes), etc.

[0026] The agricultural preparations can be seed treatment suspensions, seed treatment emulsions, seed treatment microcapsule suspensions, seed treatment dry powders, and granules.

[0027] The above-mentioned preparation can also be used in the formulations for controlling other underground pests which need to improve the adhesion.

[0028] The adhesion ability, i.e., the degree of adhesion, is determined in accordance with the determination of adhesion in 4.12 of the product standard HG / T5443-2018 for thiamethoxam seed treatment suspension.

[0029] Compared with the prior art, the technical solution of the present invention has the following advantages:

[0030] The present invention finds that for the system of preparing corresponding seed treatment agents from nicotine and diamide compounds, when lignin additives are used in combination with starch, at a suitable ratio, it can achieve excellent effect of improving adhesion. Lignin production is second only to cellulose, and it is the most abundant aromatic compound that can be obtained from renewable resources. It has outstanding production capacity worldwide, and it is non-toxic and cheap. Lignin-based adsorption materials are one of the ways to utilize lignin in a high-value manner. Lignin can introduce various chemical groups through its phenolic hydroxyl groups to meet product needs. At the same time, these two types of lignin and starch are both degradable and environmentally friendly substances. Compared with the functional additive film-forming substances that solve the adhesion problem in the prior art, they can significantly improve the effect of solving the adhesion problem and shorten the drying time. In addition, the technical solution adopted by them also has important environmental significance. DETAILED DESCRIPTION

[0031] The following specific examples are used to further illustrate the present invention, but the present invention is by no means limited to these examples. Methods well known to those skilled in the art are all included in the scope of the present invention. The percentages and parts in the formula are all by weight. The preparation of compound A is obtained by referring to the relevant records in (CN 112457288 B), and the dosage is added after 100%, and the proportion of each component is weight percentage. All other raw materials are commercially available.

[0032] The invention aims to improve the adhesion under underground application conditions, and does not use conventional polymer film-forming materials, but uses lignin and plant starch as key substances instead to form an insecticide for controlling underground pests.

[0033] Preparation formula example

[0034] Comparative Example 1-1.12% Imidacloprid seed treatment suspension

[0035] According to the formula requirements, imidacloprid 12%, YUS-FS3000 0.8%, magnesium aluminum silicate 1%, xanthan gum 0.2%, warning agent Red 5%, polyvinyl alcohol 0.4%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 12% imidacloprid seed treatment suspension can be obtained by discharging the material.

[0036] Comparative Example 1-2. 12% Imidacloprid seed treatment suspension

[0037] According to the formula requirements, imidacloprid 12%, Ultrazine NA 0.8%, magnesium aluminum silicate 1%, xanthan gum 0.2%, warning agent Red 5%, polyvinyl alcohol 0.4%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 12% imidacloprid seed treatment suspension can be obtained.

[0038] Example 1. 12% Imidacloprid seed treatment suspension

[0039] According to the formula requirements, imidacloprid 12%, Ultrazine NA 0.8%, magnesium aluminum silicate 1%, xanthan gum 0.2%, warning agent Red 5%, corn starch 0.4%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 12% imidacloprid seed treatment suspension can be obtained by discharging the material.

[0040] Comparative Example 2-1.20% Thiamethoxam seed treatment suspension

[0041] According to the formula requirements, thiamethoxam 20%, AEO-5 4%, magnesium aluminum silicate 0.8%, xanthan gum 0.1%, warning color agent Red 5%, polyvinyl alcohol 2%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 20% thiamethoxam seed treatment suspension can be obtained by discharging the material.

[0042] Comparative Example 2-2.20% Thiamethoxam seed treatment suspension

[0043] According to the formula requirements, thiamethoxam 20%, Ultrazine NA 4%, magnesium aluminum silicate 0.8%, xanthan gum 0.1%, warning color agent Red 5%, polyvinyl alcohol 2%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 20% thiamethoxam seed treatment suspension can be obtained by discharging the material.

[0044] Example 2. 20% Thiamethoxam seed treatment suspension

[0045] According to the formula requirements, 20% thiamethoxam, 4% Ultrazine NA, 0.8% magnesium aluminum silicate, 0.1% xanthan gum, 5% warning color agent Red, and 2% corn starch are added with water according to the formula ratio to 100%, and the mixture is put into a sand mill for sand grinding, and the 20% thiamethoxam seed treatment suspension can be obtained by discharging the material.

[0046] Comparative Example 3-1.30% Thiamethoxam seed treatment suspension

[0047] According to the formula requirements, thiamethoxam 30%, 127FL 4%, magnesium aluminum silicate 0.6%, xanthan gum 0.12%, warning color agent Red 7%, polyvinyl alcohol 2%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 30% thiamethoxam seed treatment suspension can be obtained by discharging the material.

[0048] Comparative Example 3-2.30% Thiamethoxam seed treatment suspension

[0049] According to the formula requirements, thiamethoxam 30%, Ultrazine NA 4%, magnesium aluminum silicate 0.6%, xanthan gum 0.12%, warning color agent Red 7%, polyvinyl alcohol 2%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 30% thiamethoxam seed treatment suspension can be obtained by discharging the material.

[0050] Comparative Example 3-3. 30% Thiamethoxam seed treatment suspension

[0051] According to the formula requirements, thiamethoxam 30%, Ultrazine NA 12%, magnesium aluminum silicate 0.6%, xanthan gum 0.12%, warning color agent Red 7%, corn starch 3%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 30% thiamethoxam seed treatment suspension can be obtained by discharging the material.

[0052] Example 3. 30% Thiamethoxam seed treatment suspension

[0053] According to the formula requirements, 30% thiamethoxam, 4% Ultrazine NA, 0.6% magnesium aluminum silicate, 0.12% xanthan gum, 7% warning color agent Red, and 2% corn starch are added with water according to the formula ratio to 100%, and the mixture is put into a sand mill for sand grinding, and the 30% thiamethoxam seed treatment suspension can be obtained by discharging the material.

[0054] Comparative Example 4-1.40% Clothianidin seed treatment suspension

[0055] According to the formula requirements, 40% of clothianidin A, 15% of Tween-80, 0.2% of magnesium aluminum silicate, 0.08% of xanthan gum, 8% of warning color agent Red, and 5% of polyvinyl alcohol are added with water according to the formula ratio to 100%, and the mixture is put into a sand mill for sand grinding, and the 40% clothianidin seed treatment suspension can be obtained by discharging the material.

[0056] Comparative Example 4-2.40% Clothianidin seed treatment suspension

[0057] According to the formula requirements, 40% clothianidin, 15% Borresperse NA, 0.2% magnesium aluminum silicate, 0.08% xanthan gum, 8% warning color agent Red, and 5% polyvinyl alcohol are added with water to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 40% clothianidin seed treatment suspension can be obtained by discharging the material.

[0058] Example 4. 40% Clothianidin seed treatment suspension

[0059] According to the formula requirements, 40% clothianidin, 15% Borresperse NA, 0.2% magnesium aluminum silicate, 0.08% xanthan gum, 8% warning color agent Red, and 5% corn starch are added with water according to the formula ratio to 100%, and the mixture is put into a sand mill for sand grinding, and the 40% clothianidin seed treatment suspension can be obtained by discharging the material.

[0060] Comparative Example 5. 10% Clothianidin Granules

[0061] According to the formula requirements, 10% clothianidin and 8% diatomaceous earth are mixed to obtain a mother powder, and then 5% polyvinyl alcohol is added and mixed with quartz sand to obtain 10% clothianidin granules.

[0062] Example 5. 10% Clothianidin granules

[0063] According to the formula requirements, 10% of clothianidin and 8% of diatomaceous earth are mixed to obtain a mother powder, and then 5% corn starch, 10% Borresperse NA and quartz sand are added and mixed to obtain 10% clothianidin granules.

[0064] Comparative Example 6-1.60% Imidacloprid seed treatment suspension

[0065] According to the formula requirements, imidacloprid 60%, SP 27001 15%, magnesium aluminum silicate 0.1%, xanthan gum 0.06%, warning agent Red 9%, polyvinyl alcohol 5%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 60% imidacloprid seed treatment suspension can be obtained by discharging the material.

[0066] Comparative Example 6-2.60% Imidacloprid Seed Treatment Suspension

[0067] According to the formula requirements, imidacloprid 60%, Borresperse NA 15%, magnesium aluminum silicate 0.1%, xanthan gum 0.06%, warning color agent Red 9%, polyvinyl alcohol 5%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 60% imidacloprid seed treatment suspension can be obtained by discharging the material.

[0068] Comparative Example 6-3.60% Imidacloprid Seed Treatment Suspension

[0069] According to the formula requirements, imidacloprid 60%, Borresperse NA 15%, magnesium aluminum silicate 0.1%, xanthan gum 0.06%, warning agent Red 9%, corn starch 3%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 60% imidacloprid seed treatment suspension can be obtained by discharging the material.

[0070] Example 6. 60% Imidacloprid seed treatment suspension

[0071] According to the formula requirements, imidacloprid 60%, Borresperse NA 15%, magnesium aluminum silicate 0.1%, xanthan gum 0.06%, warning agent Red 9%, corn starch 5%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 60% imidacloprid seed treatment suspension can be obtained by discharging the material.

[0072] Comparative Example 7. 0.5% Compound A Granules

[0073] According to the formula requirements, 0.5% of compound A and 8% of diatomaceous earth are mixed to obtain a mother powder, and then 5% of polyvinyl alcohol and quartz sand are added and mixed to obtain 0.5% compound A granules.

[0074] Example 7. 0.5% Compound A Granules

[0075] According to the formula requirements, 0.5% of compound A and 8% of diatomaceous earth are mixed to obtain a mother powder, and then 5% corn starch, 10% Borresperse NA and quartz sand are added and mixed to obtain 0.5% compound A granules.

[0076] Comparative Example 8-1.12% Compound A seed treatment suspension

[0077] According to the formula requirements, compound A 12%, YUS-FS3000 0.8%, magnesium aluminum silicate 1%, xanthan gum 0.2%, warning agent Red 5%, polyvinyl alcohol 0.4%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 12% compound A seed treatment suspension can be obtained.

[0078] Comparative Example 8-2.12% Compound A seed treatment suspension

[0079] According to the formula requirements, compound A 12%, Ultrazine NA 0.8%, magnesium aluminum silicate 1%, xanthan gum 0.2%, warning color agent Red 5%, polyvinyl alcohol 0.4%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 12% compound A seed treatment suspension can be obtained.

[0080] Example 8. 12% Compound A seed treatment suspension

[0081] According to the formula requirements, compound A 12%, Ultrazine NA 0.8%, magnesium aluminum silicate 1%, xanthan gum 0.2%, warning color agent Red 5%, corn starch 0.4%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 12% compound A seed treatment suspension can be obtained by discharging the material.

[0082] Example 9. 12% Compound A seed treatment microcapsule suspension

[0083] According to the formula requirements, compound A 12%, Ultrazine NA 0.8%, sodium polyacrylate 2.5%, polyurea prepolymer 8%, styrene maleic anhydride copolymer 1%, S150# 10%, hydrochloric acid 3%, sodium hydroxide 0.01%, xanthan gum 0.01%, warning agent Red 5%, corn starch 0.4% are added with water to 100% according to the formula ratio, added into the sand-ground slurry and mixed and stirred evenly to obtain 12% compound A seed treatment microcapsule suspension.

[0084] Comparative Example 10-1.20% Compound A seed treatment suspension

[0085] According to the formula requirements, compound A 20%, AEO-5 4%, magnesium aluminum silicate 0.8%, xanthan gum 0.1%, warning color agent Red 5%, polyvinyl alcohol 2%, water is added to 100% according to the formula ratio, put into a sand mill for sand grinding, and the material can be discharged to obtain 20% compound A seed treatment suspension.

[0086] Comparative Example 10-2.20% Compound A seed treatment suspension

[0087] According to the formula requirements, compound A 20%, Ultrazine NA 4%, magnesium aluminum silicate 0.8%, xanthan gum 0.1%, warning color agent Red 5%, polyvinyl alcohol 2%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 20% compound A seed treatment suspension can be obtained.

[0088] Example 10. 20% Compound A seed treatment suspension

[0089] According to the formula requirements, compound A 20%, Ultrazine NA 4%, magnesium aluminum silicate 0.8%, xanthan gum 0.1%, warning color agent Red 5%, corn starch 2%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 20% compound A seed treatment suspension can be obtained.

[0090] Comparative Example 11-1.30% Compound A seed treatment suspension

[0091] According to the formula requirements, compound A 30%, 127FL4%, magnesium aluminum silicate 0.6%, xanthan gum 0.12%, warning color agent Red 7%, polyvinyl alcohol 2%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 30% compound A seed treatment suspension can be obtained.

[0092] Comparative Example 11-2.30% Compound A seed treatment suspension

[0093] According to the formula requirements, 30% of compound A, 4% of Ultrazine NA, 0.6% of magnesium aluminum silicate, 0.12% of xanthan gum, 7% of warning color agent Red, and 2% of polyvinyl alcohol are added with water according to the formula ratio to 100%, and the mixture is put into a sand mill for sand grinding, and the 30% compound A seed treatment suspension can be obtained by discharging the material.

[0094] Comparative Example 11-3. 30% Compound A seed treatment suspension

[0095] According to the formula requirements, compound A 30%, Ultrazine NA 12%, magnesium aluminum silicate 0.6%, xanthan gum 0.12%, warning color agent Red 7%, corn starch 2%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 30% compound A seed treatment suspension can be obtained.

[0096] Example 11. 30% Compound A seed treatment suspension

[0097] According to the formula requirements, 30% of compound A, 4% of Ultrazine NA, 0.6% of magnesium aluminum silicate, 0.12% of xanthan gum, 7% of warning color agent Red, and 2% of corn starch are added with water according to the formula ratio to 100%, and the mixture is put into a sand mill for sand grinding, and the 30% compound A seed treatment suspension can be obtained by discharging the material.

[0098] Example 12. 30% Compound A seed treatment emulsion

[0099] According to the formula requirements, compound A 30%, 127FL 4%, Ultrazine NA 0.8%, S150#25%, warning agent Red 5%, corn starch 2.4%, water is added to 100% according to the formula ratio, and high shear is applied at 12000rpm for 15 minutes to obtain a 30% compound A seed treatment emulsion.

[0100] Comparative Example 13-1.40% Compound A seed treatment suspension

[0101] According to the formula requirements, compound A 40%, Tween-80 15%, magnesium aluminum silicate 0.2%, xanthan gum 0.08%, warning color agent Red 8%, polyvinyl alcohol 5%, water is added to 100% according to the formula ratio, put into a sand mill for sand grinding, and the material can be discharged to obtain 40% compound A seed treatment suspension.

[0102] Comparative Example 13-2.40% Compound A seed treatment suspension

[0103] According to the formula requirements, 40% of compound A, 15% of Borresperse NA, 0.2% of magnesium aluminum silicate, 0.08% of xanthan gum, 8% of warning color agent Red, and 5% of polyvinyl alcohol are added with water to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 40% compound A seed treatment suspension can be obtained.

[0104] Example 13. 40% Compound A seed treatment suspension

[0105] According to the formula requirements, 40% of compound A, 15% of Borresperse NA, 0.2% of magnesium aluminum silicate, 0.08% of xanthan gum, 8% of warning color agent Red, and 5% of corn starch are added with water according to the formula ratio to 100%, and the mixture is put into a sand mill for sand grinding, and the 40% compound A seed treatment suspension can be obtained by discharging the material.

[0106] Comparative Example 14-1.60% Compound A seed treatment suspension

[0107] According to the formula requirements, compound A 60%, SP 27001 15%, magnesium aluminum silicate 0.1%, xanthan gum 0.06%, warning color agent Red 9%, polyvinyl alcohol 5%, water is added to 100% according to the formula ratio, put into a sand mill for sand grinding, and the 60% compound A seed treatment suspension can be obtained by discharging.

[0108] Comparative Example 14-2.60% Compound A seed treatment suspension

[0109] According to the formula requirements, compound A 60%, Borresperse NA 15%, magnesium aluminum silicate 0.1%, xanthan gum 0.06%, warning color agent Red 9%, polyvinyl alcohol 5%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 60% compound A seed treatment suspension can be obtained.

[0110] Example 14. 60% Compound A seed treatment suspension

[0111] According to the formula requirements, compound A 60%, Borresperse NA 15%, magnesium aluminum silicate 0.1%, xanthan gum 0.06%, warning color agent Red 9%, corn starch 5%, water is added to 100% according to the formula ratio, and the mixture is put into a sand mill for sand grinding, and the 60% compound A seed treatment suspension can be obtained.

[0112] Example 15. 60% Compound A Seed Treatment Dry Powder

[0113] According to the formula requirements, 60% of compound A, 15% of Borresperse NA, 0.5% of rose essence, 2% of diatomaceous earth, 7.5% of corn starch, and the balance of light calcium carbonate are supplemented to 100%. After air flow grinding, a 60% compound A seed treatment dry powder can be obtained.

[0114] Application performance measurement:

[0115] The seed treatment agents in the above examples were coated on corn seeds, and the following properties were measured after coating.

[0116] This method mainly involves pouring the coated sample through the upper glass funnel onto the guide slot partition door, opening the partition door, and allowing the seeds to freely fall onto the sieve at a fixed height. The drug powder that falls off the seeds is separated through the sieve. The above process is repeated 5 times, and the drug content remaining on the seeds is determined and compared with the drug content on untested seeds to calculate the drug adhesion. The adhesion test device used is detailed in the Thiamethoxam Seed Treatment Suspension Concentrate Standard HG / T 5443-2018.

[0117] Weigh 100g (accurate to 1g) of corn seeds in a petri dish for later use. Use a syringe to draw 0.33g of the sample and inject it into a beaker, then add 9.67g of deionized water and mix well. Draw 1g of the seed treatment agent sample mixture prepared in the above examples and inject it into the petri dish, cover it and shake it for 1min, then spread the coated seeds flat and place them until the liquid is dry for later use.

[0118] 330 g of seeds treated as above were stored at a temperature of (23±5)°C and a relative humidity of 40% to 60% for at least 24 hours.

[0119] Weigh three 20g samples from the prepared seed samples into three conical flasks, add 50mL of methanol, and oscillate ultrasonically until the dye on the seed surface is completely dissolved. Take out, let stand for 10 minutes or centrifuge, and determine the mass of the active ingredient.

[0120] The remaining 270g of seeds were divided into 3 equal parts and tested as follows: 90g of the sample was slowly poured into the glass cylindrical guide groove through the upper glass funnel. When all the seeds reached the bottom of the guide groove, the partition door was opened to allow the seeds to fall freely onto the sieve, and the partition door was closed. There is no need to clean the experimental device during the seed falling process. Repeat the above process 4 times. Take out 20g of sample for testing the dosage of seed medicine. Before conducting the next batch of sample experiments, clean the residual powder on the guide groove, sieve and device. Repeat the above experimental process for the remaining 2 samples. After the drop test is completed, take out 3 20g samples from each of the 3 conical flasks, add 50mL of methanol, and oscillate ultrasonically until the dye on the surface of the seeds is completely dissolved. Take it out, let it stand for 10 minutes or centrifuge it, and determine the mass of the active ingredient.

[0121] The adhesion is calculated according to formula (1):

[0122]

[0123] Where:

[0124] ω2—Adhesion degree of the sample, in percentage (%);

[0125] m' - the average value of the mass of the active ingredient in three samples after the drop test, in grams (g);

[0126] m—The average value of the mass of the active ingredient in three samples that have not been subjected to the drop test, in grams (g).

[0127] Table 1 shows the data of the adhesion measured after the preparations were prepared in the examples and coated on the seeds. From the data in the table, it can be seen that the schemes in bold font all use a formulation system of lignin sulfonate compounded with corn starch, and their adhesion is significantly improved, and under the appropriate ratio, it has a significant effect of improving the adhesion.

[0128] Table 1 Adhesion of coated seeds

[0129]

[0130]

[0131] From the data in the table, it can be seen that among the three solutions of using polyvinyl alcohol alone, lignin plus polyvinyl alcohol, and lignin plus starch, only the formula after using lignin sulfonate combined with corn starch has a significant improvement in the adhesion value, and under the appropriate ratio, the improvement effect is more obvious. Further performance measurement of the seed package preparation obtained above:

[0132] The corn seeds of the above-mentioned Examples 6 and 11 were coated respectively, and the seed germination safety under the formulation was determined according to the preparation dosage of 200 ml / 100 kg of seeds and 600 ml / 100 kg of seeds, respectively. The present invention adopts GB / T3543.4-1995 Inspection Procedure for Seeds of Crops-Germination Test. Germination refers to the appearance and growth of seedlings in the laboratory to a certain stage, and the main structure of the seedlings indicates whether they can further grow into normal plants under suitable conditions in the field. Its germination potential refers to the trend of germination, which is observed on the 4th day according to relevant standards, and the germination rate is the percentage of the number of normal seedlings grown under the specified conditions and time to the number of seeds for inspection.

[0133] The experiment uses sand as the germination bed. The sand particles are uniform in size, with a diameter of 0.05-0.80mm, and the seeds are non-toxic and sterile. Wash and sterilize at high temperature before use. The sand bed adopts the sand-in-sand method, that is, the seeds are sown on a layer of flat wet sand, and then covered with 10-20mm thick loose sand according to the seed size.

[0134] The germination equipment is a germination box: with light, temperature control range 10-40℃;

[0135] According to the germination conditions specified in the standard, the low temperature is 20℃, and the germination potential and germination rate are measured at this temperature both day and night.

[0136] Germination potential is the percentage of seedlings that emerged 4 days after planting to the total number;

[0137] The germination rate is the percentage of seedlings that emerged 7 days after planting.

[0138] Among them, blank refers to blank seeds that are not coated with any agent.

[0139] Table 2 Safety data of Example 6 and Example 10

[0140]

[0141] It can be seen from Table 2 that under this technical solution, the seeds coated with the example preparations according to high and low drug-to-seed ratios can germinate normally, which is equivalent to or slightly higher than the germination of blank seeds, and has no effect on the germination rate.

Claims

1. An agricultural preparation containing nicotine or diamide compounds, characterized in that: The preparation comprises active ingredients, surfactants and functional additives; wherein the active ingredients account for 0.2-60% of the preparation mass, and the active ingredients are nicotine compounds or bisamide compounds.

2. The agricultural preparation containing nicotine or bisamide compounds according to claim 1, characterized in that: The functional additive is corn starch and / or potato starch.

3. The agricultural preparation containing nicotine or bisamide compounds according to claim 1, characterized in that: The surfactant is selected from one or more of fatty alcohol polyoxyethylene ether, polyoxyethylene polyoxypropylene ether block copolymer, sorbitan fatty acid ester polyoxyethylene ether, and lignin sulfonate.

4. The agricultural preparation containing nicotine or bisamide compounds according to any one of claims 1 to 3, characterized in that: The mass ratio of the active ingredient to the remaining components (total mass of surfactants and functional additives) is 10:1-1:1; the mass ratio of the surfactant to the functional additive is 2:1-3:

1.

5. The agricultural preparation containing nicotine or bisamide compounds according to claim 4, characterized in that: The nicotine compound is one or more of imidacloprid, thiamethoxam and clothianidin; the diamide compound is compound A; 6. The agricultural preparation containing nicotine or bisamide compounds according to claim 1, characterized in that: The formulation type can be a seed treatment suspension, a seed treatment emulsion, a seed treatment dry powder, a seed treatment microcapsule suspension, or a granule.

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