Extraction device for medicine production and use method thereof

Abstract

The invention discloses an extraction device for medicine production and a use method thereof, belongs to the field of devices for medicine production, and can solve the problems that in the background technology, an existing biopharmaceutical extraction mode is that biological tissues are crushed and then filtered and extracted, and the existing biological tissues can be adhered to the inner wall of an extraction container after being crushed and filtered, so that the extraction efficiency is high. After extraction each time, disassembly and cleaning are needed, then installation is conducted, and the problems that the next extraction is affected by residual biological tissue, the mode is tedious, cleaning is time-consuming and labor-consuming, and the extraction progress of the biological tissue is reduced are solved. The method comprises the steps that S1, the biological tissue is put into a crushing barrel through a feeding opening; s2, electrifying a motor to drive a crushing roller to rotate to crush the biological tissue; s3, a control valve is closed, and an electric telescopic rod is powered on to drive a filter plate to move upwards for extraction; and S4, water is introduced into the water pipe, and water is sprayed out through the water spraying holes for cleaning.

Description

Technical Field

[0001] The invention belongs to the field of medical production equipment, in particular to an extraction device for medical drug production and a use method thereof. Background Art

[0002] The biopharmaceutical process refers to the process of extracting effective drug substances from organisms through the use of biotechnology, and finally producing drugs through a series of processing. The existing biopharmaceutical extraction method is to crush the biological tissue and then filter and extract it. After the existing biological tissue is crushed and filtered, the biological tissue will stick to the inner wall of the extraction container. After each extraction, it needs to be disassembled and cleaned, and then installed again to avoid the residual biological tissue affecting the next extraction. The above method is cumbersome, time-consuming and labor-intensive to clean, which will reduce the extraction progress of biological tissue. Summary of the invention

[0003] The purpose of the present invention is to solve the above problems existing in the prior art and to provide an extraction device for the production of pharmaceuticals and a method for using the same.

[0004] To achieve the above purpose, the present invention adopts the following technical solutions:

[0005] An extraction device for producing medicines and drugs comprises: a support frame, a crushing device and an extraction device. The crushing device is fixed on the support frame, and the lower end of the crushing device is fixedly connected to the extraction device.

[0006] The crushing device includes: a crushing barrel, a feed port, a motor, a crushing roller, an upper eccentric plate, a crushing roller groove, a lower eccentric plate, a filter screen and a discharge port. The crushing barrel is fixed on the support frame, the upper end of the crushing barrel is provided with a feed port, the upper end of the crushing barrel is fixed with a motor, the crushing roller is arranged inside the crushing barrel, the upper end of the crushing roller is rotatably connected to the upper eccentric plate, the motor output shaft is fixedly connected to the upper eccentric plate, the bottom surface of the crushing roller is provided with a crushing roller groove, the top surface of the crushing roller groove is rotatably connected to the lower eccentric plate, the lower end of the lower eccentric plate is rotatably connected to the bottom surface of the crushing barrel, the bottom surface of the crushing barrel is provided with a bottom hole, a filter screen is detachably fixed in the bottom hole, the bottom hole and the filter screen are both provided with a plurality of bottom holes and the filter screen, and a discharge port is fixedly provided on the bottom surface of the crushing barrel.

[0007] The bottom surface of the crushing roller is slidably attached to the bottom surface of the crushing barrel, and the top surface of the crushing roller is configured as a wedge-shaped surface.

[0008] The extraction device includes: an extraction barrel, an extraction barrel inlet, a control valve, a guide column, a filter unit and an electric telescopic rod. The upper end of the extraction barrel is provided with an extraction barrel inlet, the extraction barrel inlet is provided with a control valve, the extraction barrel inlet is fixedly connected with a discharge port, the inside of the extraction barrel is symmetrically fixed with guide columns, the filter unit is slidably sealed with the guide columns, the side wall of the filter unit is slidably sealed with the inner wall of the extraction barrel, an electric telescopic rod is fixed to the inner bottom surface of the extraction barrel, and the movable end of the electric telescopic rod is fixedly connected with the bottom surface of the filter unit.

[0009] The filter unit comprises: a filter plate, a water spray hole, an annular connecting pipe, a water inlet, a spring, a sealing plug, a conical groove, a thread, a filter membrane fixing ring, an upper pressure ring, an upper pressure ring groove, a filter membrane, a lower pressure ring and an annular protrusion. The filter plate is slidably sealed with a guide column, and the side wall of the filter plate is slidably sealed with the inner wall of the extraction barrel. A plurality of water spray holes opening upward are evenly arranged on the filter plate. An annular connecting pipe is arranged inside the filter plate, and the annular connecting pipe is connected with the bottom of the plurality of water spray holes. A water inlet hole is arranged at the lower end of the annular connecting pipe. A spring is fixed in each of the water spray holes through a spring bracket. The sealing plug is sealed against the upper end of the water spray hole. The upper end of the spring is fixedly connected to the bottom surface of the sealing plug, the filter plate is provided with a conical groove, the conical groove is provided with a downward notch, and the side wall of the notch is provided with a thread, the upper end of the filter membrane fixing ring is screwed together with the thread for sealing, the lower end of the filter membrane fixing ring is fixed with an upper pressure ring, the bottom surface of the upper pressure ring is provided with an upper pressure ring groove, the upper end of the lower pressure ring is provided with an annular protrusion, the filter membrane is arranged between the upper pressure ring and the lower pressure ring, the upper pressure ring and the lower pressure ring are detachably fixedly connected by bolts, the annular protrusion is arranged in the upper pressure ring groove, the filter membrane is arranged between the annular protrusion and the upper pressure ring groove, and the movable end of the electric telescopic rod is fixedly connected to the bottom surface of the filter plate.

[0010] The water inlet is fixedly connected with a water pipe, and the lower end of the lower pressure ring is fixedly connected with a hose.

[0011] A method for using an extraction device for producing pharmaceutical drugs, the method comprising the following steps:

[0012] S1: Put the biological tissue into the crushing barrel through the feed port;

[0013] S2: Powering on the motor to drive the crushing roller to rotate and crush the biological tissue;

[0014] S3: Close the control valve and energize the electric telescopic rod to drive the filter plate to move upward for extraction;

[0015] S4: Pass water through the water pipe, and the water is sprayed out through the water spray hole for cleaning.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] The present invention provides an extraction device for the production of pharmaceutical drugs, which can solve the problem raised in the background technology: the existing biopharmaceutical extraction method is to crush the biological tissue and then filter and extract it. After the existing biological tissue is crushed and filtered, the biological tissue will stick to the inner wall of the extraction container. After each extraction, it needs to be disassembled and cleaned, and then installed again to avoid the residual biological tissue affecting the next extraction. The above method is cumbersome, time-consuming and labor-intensive to clean, which will reduce the extraction progress of the biological tissue. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the overall structure.

[0019] Figure 2 It is a top view of the bottom of the crushing barrel;

[0020] Figure 3 is a schematic diagram of the extraction device structure;

[0021] Figure 4 It is a schematic diagram of the filter unit structure;

[0022] Figure 5 is a top view of the filter plate;

[0023] Figure 6 It is a partial enlarged view of the filter unit;

[0024] Figure 7 It is a top view of the upper pressure ring groove;

[0025] Figure 8 It is a cross-sectional view of the lower pressure ring. DETAILED DESCRIPTION

[0026] The technical solution of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0027] An extraction device for producing medicines and drugs comprises: a support frame 1, a crushing device 2 and an extraction device 3. The crushing device 2 is fixed on the support frame 1, and the lower end of the crushing device 2 is fixedly connected to the extraction device 3.

[0028] The crushing device 2 includes: a crushing barrel 2-1, a feed port 2-2, a motor 2-3, a crushing roller 2-4, an upper eccentric plate 2-5, a crushing roller slot 2-6, a lower eccentric plate 2-7, a filter screen 2-8 and a discharge port 2-9. The crushing barrel 2-1 is fixed on the support frame 1. The upper end of the crushing barrel 2-1 is provided with a feed port 2-2. The upper end of the crushing barrel 2-1 is fixed with a motor 2-3. The crushing roller 2-4 is arranged inside the crushing barrel 2-1. The upper end of the crushing roller 2-4 is connected to the upper eccentric plate 2-5. Rotatably connected, the output shaft of the motor 2-3 is fixedly connected to the upper eccentric plate 2-5, the bottom surface of the crushing roller 2-4 is provided with a crushing roller groove 2-6, the top surface of the crushing roller groove 2-6 is rotatably connected with the lower eccentric plate 2-7, the lower end of the lower eccentric plate 2-7 is rotatably connected to the bottom surface of the crushing barrel 2-1, the bottom surface of the crushing barrel 2-1 is provided with a bottom hole, a filter screen 2-8 is detachably fixed in the bottom hole, the bottom hole and the filter screen 2-8 are both provided in multiple numbers, and a discharge port 2-9 is fixed to the bottom surface of the crushing barrel 2-1.

[0029] The bottom surface of the crushing roller 2-4 is slidably attached to the bottom surface of the crushing barrel 2-1, and the top surface of the crushing roller 2-4 is set as a wedge-shaped surface.

[0030] The extraction device 3 includes: an extraction barrel 3-1, an extraction barrel inlet 3-2, a control valve 3-3, a guide column 3-4, a filter unit 3-5 and an electric telescopic rod 3-6. The extraction barrel 3-1 is provided with an extraction barrel inlet 3-2 at the upper end, and the extraction barrel inlet 3-2 is provided with a control valve 3-3. The extraction barrel inlet 3-2 is fixedly connected with the discharge port 2-9. The extraction barrel 3-1 is symmetrically fixed with guide columns 3-4. The filter unit 3-5 is slidably sealed with the guide columns 3-4. The side wall of the filter unit 3-5 is slidably sealed with the inner wall of the extraction barrel 3-1. The inner bottom surface of the extraction barrel 3-1 is fixed with an electric telescopic rod 3-6, and the movable end of the electric telescopic rod 3-6 is fixedly connected with the bottom surface of the filter unit 3-5.

[0031] The filter unit 3-5 includes: a filter plate 3-5-1, a water spray hole 3-5-2, an annular connecting pipe 3-5-3, a water inlet 3-5-4, a spring 3-5-5, a sealing plug 3-5-6, a conical groove 3-5-7, a thread 3-5-8, a filter membrane fixing ring 3-5-9, an upper pressure ring 3-5-10, an upper pressure ring groove 3-5-11, a filter membrane 3-5-12, a lower pressure ring 3-5-13 and an annular protrusion 3-5-14. The filter plate 3-5-1 is slidably sealed with the guide column 3-4. The filter plate 3-5-1 side The filter plate 3-5-1 is evenly distributed with a plurality of upwardly opening water spray holes 3-5-2, and an annular connecting pipe 3-5-3 is arranged inside the filter plate 3-5-1. The annular connecting pipe 3-5-3 is connected with the bottom of the plurality of water spray holes 3-5-2, and a water inlet hole is arranged at the lower end of the annular connecting pipe 3-5-3. A spring 3-5-5 is fixed in each of the water spray holes 3-5-2 through a spring bracket, and the sealing plug 3-5-6 is sealed against the water spray hole 3-5-2. The upper end of the spring 3-5-5 is fixedly connected to the bottom surface of the sealing plug 3-5-6, the filter plate 3-5-1 is provided with a conical groove 3-5-7, the conical groove 3-5-7 is provided with a notch facing downward, and a thread 3-5-8 is provided on the side wall of the notch. The upper end of the filter membrane fixing ring 3-5-9 is screwed and sealed with the thread 3-5-8, and the lower end of the filter membrane fixing ring 3-5-9 is fixed with an upper pressure ring 3-5-10, and the bottom surface of the upper pressure ring 3-5-10 is provided with an upper pressure ring groove 3-5-11, and the lower pressure ring 3- An annular protrusion 3-5-14 is arranged on the upper end of 5-13, and the filter membrane 3-5-12 is arranged between the upper pressure ring 3-5-10 and the lower pressure ring 3-5-13. The upper pressure ring 3-5-10 and the lower pressure ring 3-5-13 are detachably fixedly connected by bolts, and the annular protrusion 3-5-14 is arranged in the upper pressure ring groove 3-5-11. The filter membrane 3-5-12 is arranged between the annular protrusion 3-5-14 and the upper pressure ring groove 3-5-11, and the movable end of the electric telescopic rod 3-6 is fixedly connected to the bottom surface of the filter plate 3-5-1.

[0032] The water inlet 3-5-4 is fixedly connected with a water pipe, and the lower end of the lower pressure ring 3-5-13 is fixedly connected with a hose.

[0033] A method for using an extraction device for producing pharmaceutical drugs, the method comprising the following steps:

[0034] S1: Put the biological tissue into the crushing barrel 2-1 through the feed port 2-2;

[0035] S2: energizing the motor 2-3 to drive the crushing roller 2-4 to rotate and crush the biological tissue;

[0036] S3: Close the control valve 3-3 and energize the electric telescopic rod 3-6 to drive the filter plate 3-5-1 to move upward for extraction;

[0037] S4: Let water flow through the water pipe, and the water will be sprayed out through the water spray hole 3-5-2 for cleaning.

[0038] The working principle of the present invention is:

[0039] When in use, biological tissue is put into the crushing barrel 2-1 through the feed port 2-2. The device is connected to an external power supply. The motor 2-3 is energized through the upper eccentric plate 2-5 to drive the crushing roller 2-4 to rotate eccentrically with the lower eccentric plate 2-7 as the center. When the crushing roller 2-4 rotates eccentrically, the biological tissue can be squeezed and crushed by cooperating with the inner wall of the crushing barrel 2-1, thereby crushing the biological tissue. The top surface of the crushing roller 2-4 is set as a wedge-shaped surface. When the biological tissue falls on the top surface of the crushing roller 2-4, it can slide along to between the crushing barrel 2-1 and the crushing roller 2-4, so as to prevent the biological tissue from falling on the crushing roller 2-4 and not being crushed. After the biological tissue is crushed, it slides through the filter screen 2-8, is collected through the discharge port 2-9, and then is imported through the extraction barrel 3-2 enters the extraction barrel 3-1, the filter screen 2-8 can be replaced and cleaned according to the biological tissue that needs to be broken, and the crushing roller 2-4 repeatedly breaks the biological tissue until the biological tissue can pass through the filter screen 2-8. When the biological tissue broken by the crushing roller 2-4 all slides into the extraction barrel 3-1, the control valve 3-3 is closed to make the extraction barrel 3-1 closed, and then the electric telescopic rod 3-6 is energized to drive the filter plate 3-5-1 to move upward along the guide column 3-4. The guide column 3-4 guides and limits the filter plate 3-5-1. The filter plate 3-5-1 moves upward and cooperates with the top surface of the extraction barrel 3-1 to squeeze the biological tissue, thereby generating pressure on the biological tissue. The force is applied to squeeze out the tissue fluid in the biological tissue, and the biological tissue fluid can be filtered through the filter membrane 3-5-12. The biological tissue fluid passes through the filter membrane 3-5-12 and then flows into the hose for collection. When the squeezing is completed, the filter membrane fixing ring 3-5-9 is unscrewed, and the bolts fixing the upper pressure ring 3-5-10 and the lower pressure ring 3-5-13 are removed. The filter membrane 3-5-12 can be replaced, and then the water pipe is passed through. The water enters the annular connecting pipe 3-5-3 through the water pipe, and then enters the water spray hole 3-5-2 through the annular connecting pipe 3-5-3. The sealing plug 3-5-6 is pushed apart from the water spray hole 3-5-2 by the water pressure to produce a gap, and the spring 3-5-5 is stretched at the same time. The water is sprayed out through the gap to the extraction barrel. The inner wall of the extraction bucket 3-1 is rinsed, and the sealing plug 3-5-6 is an inverted cone. When the water is sprayed out, it flows along the outer wall of the sealing plug 3-5-6, which can change the direction of the water flow, so that the water flow can be better rinsed on the inner wall of the extraction bucket 3-1, and the flushing area can be increased. While flushing, the electric telescopic rod 3-6 is powered on and reset, and the electric telescopic rod 3-6 drives the filter plate 3-5-1 to move downward and reset, which can achieve the effect of resetting and cleaning. The cleaned sewage flows out through the conical groove 3-5-7, and the sewage pipe can be connected at the notch at the lower end of the conical groove 3-5-7 for sewage discharge. When the filter plate 3-5-1 is reset, the water is turned off, and the sealing plug 3-5-6 is reset by the spring 3-5-5, and the next biological tissue extraction can be carried out.

[0040] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered in all respects as exemplary and non-limiting, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations within the meaning and range of equivalents of the claims be included in the invention. Any reference numeral in a claim should not be considered as limiting the claim to which it relates.

[0041] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. An extraction device for the production of pharmaceuticals, characterized in that: include: A support frame (1), a crushing device (2) and an extraction device (3), wherein the crushing device (2) is fixed on the support frame (1), and the lower end of the crushing device (2) is fixedly connected to the extraction device (3).

2. The extraction device for producing pharmaceutical products according to claim 1, characterized in that: The crushing device (2) comprises: a crushing barrel (2-1), a feed port (2-2), a motor (2-3), a crushing roller (2-4), an upper eccentric plate (2-5), a crushing roller groove (2-6), a lower eccentric plate (2-7), a filter screen (2-8) and a discharge port (2-9); the crushing barrel (2-1) is fixed on the support frame (1); the upper end of the crushing barrel (2-1) is provided with a feed port (2-2); the upper end of the crushing barrel (2-1) is fixed with a motor (2-3); the crushing roller (2-4) is arranged inside the crushing barrel (2-1); the upper end of the crushing roller (2-4) is connected to the upper eccentric plate (2-5), and the crushing roller groove (2-6) is connected to the lower eccentric plate (2-7). The motor (2-3) is rotatably connected to the upper eccentric plate (2-5), the output shaft of the motor (2-3) is fixedly connected to the upper eccentric plate (2-5), the bottom surface of the crushing roller (2-4) is provided with a crushing roller groove (2-6), the top surface of the crushing roller groove (2-6) is rotatably connected to the lower eccentric plate (2-7), the lower end of the lower eccentric plate (2-7) is rotatably connected to the bottom surface of the crushing barrel (2-1), the bottom surface of the crushing barrel (2-1) is provided with a bottom hole, a filter screen (2-8) is detachably fixed in the bottom hole, the bottom hole and the filter screen (2-8) are both provided in plural numbers, and a discharge port (2-9) is fixed to the bottom surface of the crushing barrel (2-1).

3. The extraction device for producing pharmaceutical products according to claim 2, characterized in that: The bottom surface of the crushing roller (2-4) is slidably attached to the bottom surface of the crushing barrel (2-1), and the top surface of the crushing roller (2-4) is configured as a wedge-shaped surface.

4. The extraction device for producing pharmaceutical products according to claim 2, characterized in that: The extraction device (3) comprises: an extraction barrel (3-1), an extraction barrel inlet (3-2), a control valve (3-3), a guide column (3-4), a filter unit (3-5) and an electric telescopic rod (3-6); the extraction barrel (3-1) is provided with an extraction barrel inlet (3-2) at the upper end; the extraction barrel inlet (3-2) is provided with a control valve (3-3); the extraction barrel inlet (3-2) is fixedly connected to a discharge port (2-9); the extraction barrel (3-1) is symmetrically fixed with a guide column (3-4); the filter unit (3-5) is slidably sealed with the guide column (3-4); the side wall of the filter unit (3-5) is slidably sealed with the inner wall of the extraction barrel (3-1); the inner bottom surface of the extraction barrel (3-1) is fixed with an electric telescopic rod (3-6); the movable end of the electric telescopic rod (3-6) is fixedly connected with the bottom surface of the filter unit (3-5).

5. The extraction device for producing pharmaceutical products according to claim 4, characterized in that: The filter unit (3-5) comprises: a filter plate (3-5-1), a water spray hole (3-5-2), an annular connecting pipe (3-5-3), a water inlet (3-5-4), a spring (3-5-5), a sealing plug (3-5-6), a conical groove (3-5-7), a thread (3-5-8), a filter membrane fixing ring (3-5-9), an upper pressure ring (3-5-10), an upper pressure ring groove (3-5-11), a filter membrane (3-5-12), a lower pressure ring (3-5-13) and an annular protrusion (3-5-14); the filter plate (3-5-1) is slidably sealed with a guide column (3-4); the filter plate The side wall of the filter plate (3-5-1) is slidably sealed with the inner wall of the extraction barrel (3-1); a plurality of water spray holes (3-5-2) with openings facing upward are evenly arranged on the filter plate (3-5-1); an annular connecting pipe (3-5-3) is arranged inside the filter plate (3-5-1); the annular connecting pipe (3-5-3) is connected to the bottom of the plurality of water spray holes (3-5-2); a water inlet hole is arranged at the lower end of the annular connecting pipe (3-5-3); a spring (3-5-5) is fixed in each of the water spray holes (3-5-2) through a spring bracket; the sealing plug (3-5-6) is sealed against the water spray hole (3-5-6); 5-2), the upper end of the spring (3-5-5) is fixedly connected to the bottom surface of the sealing plug (3-5-6), the filter plate (3-5-1) is provided with a conical groove (3-5-7), the conical groove (3-5-7) is provided with a notch facing downwards, and a thread (3-5-8) is provided on the side wall of the notch, the upper end of the filter membrane fixing ring (3-5-9) is screwed and sealed with the thread (3-5-8), the lower end of the filter membrane fixing ring (3-5-9) is fixed with an upper pressure ring (3-5-10), the bottom surface of the upper pressure ring (3-5-10) is provided with an upper pressure ring groove (3-5-11), and the lower pressure ring (3-5-10) is provided with an upper pressure ring groove (3-5-11). -5-13) is provided with an annular protrusion (3-5-14) at the upper end, the filter membrane (3-5-12) is arranged between the upper pressure ring (3-5-10) and the lower pressure ring (3-5-13), the upper pressure ring (3-5-10) and the lower pressure ring (3-5-13) are detachably fixedly connected by bolts, the annular protrusion (3-5-14) is arranged in the upper pressure ring groove (3-5-11), the filter membrane (3-5-12) is arranged between the annular protrusion (3-5-14) and the upper pressure ring groove (3-5-11), and the movable end of the electric telescopic rod (3-6) is fixedly connected to the bottom surface of the filter plate (3-5-1).

6. The extraction device for producing pharmaceutical products according to claim 5, characterized in that: The water inlet (3-5-4) is fixedly connected to a water pipe, and the lower end of the lower pressure ring (3-5-13) is fixedly connected to a hose.

7. A method for using the extraction device for producing pharmaceutical products according to claim 6, characterized in that: The method comprises the following steps: S1: feeding the biological tissue into the crushing barrel (2-1) through the feed port (2-2); S2: energizing the motor (2-3) to drive the crushing roller (2-4) to rotate and crush the biological tissue; S3: close the control valve (3-3) and energize the electric telescopic rod (3-6) to drive the filter plate (3-5-1) to move upwards for extraction; S4: Pass water through the water pipe, and the water is sprayed out through the water spray hole (3-5-2) for cleaning.

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