Mild toothpaste matrix and preparation method thereof

Abstract

The invention relates to the technical field of extraction of plant extracts, in particular to a mild toothpaste matrix and a preparation method thereof.In the process of ultrasonic-assisted extraction of a centella asiatica extract, a standing wave effect is prone to occurring, and the thicker plant cell walls for extracting the centella asiatica extract are, the higher plant strength is, the more prone to occurring the standing wave effect; when the standing wave intensity is too large, the cell structure is excessively damaged, so that the integrity of centella asiatica extract molecules is influenced, the difficulty degree of the standing wave effect of a plant currently used for extracting the plant extract is comprehensively analyzed according to the plant cell wall thickness and the extrusion feedback condition, the control precision of the extraction process of the plant extract is improved, and the extraction efficiency of the plant extract is improved. The transmitting power and the transmitting frequency of the ultrasonic waves are further reduced according to the analysis result, so that the standing wave effect is reduced and is in a proper range, the cell structure is favorably damaged, the plant extract is released, and the extraction efficiency of the plant extract is improved.

Description

Technical Field

[0001] The invention relates to the technical field of plant extract extraction, in particular to a mild toothpaste matrix and a preparation method thereof. Background Art

[0002] Centella asiatica extract is used as an auxiliary drug raw material for anti-inflammatory and anti-oral ulcer effects in toothpaste. The existing technology mostly obtains plant extracts through solvent extraction. However, the standing wave effect is prone to occur during the extraction of plant extracts. When the standing wave intensity is too large, it will excessively destroy the cell structure, thereby affecting the integrity of the plant extract and reducing the content of effective plant extract components in the toothpaste matrix.

[0003] Chinese patent publication number: CN107440990A discloses a method for preparing a plant extract, wherein the plant extract is a chloroform extraction part of daffodil petals. The whitening skin care product provided by the invention has a significant effect, can enhance the water-locking ability of the skin, reduce the melanin content of the skin, and has the effect of whitening and moisturizing; at the same time, the product is non-irritating to the skin and is safe and reliable.

[0004] However, the prior art still has the following problems: The standing wave effect is prone to occur during the extraction process of plant extracts. When the standing wave intensity is too large, it will excessively damage the cell structure, thereby affecting the integrity of the plant extract and reducing the content of effective plant extract ingredients in the toothpaste matrix. Summary of the invention

[0005] To this end, the present invention provides a mild toothpaste base and a preparation method thereof, so as to overcome the problem that the standing wave effect is easily occurred in the extraction process of plant extracts in the prior art. When the standing wave intensity is too large, the cell structure will be excessively destroyed, thereby affecting the integrity of the plant extract and reducing the content of the components of the effective plant extract in the toothpaste base.

[0006] To achieve the above object, the present invention provides a method for preparing a mild toothpaste base. The method comprises: Obtaining a sample of the plant to be extracted, and performing a property experiment on the sample, including squeezing the sample for a predetermined stroke, obtaining a feedback force of squeezing, obtaining a fiber image of a tissue section of the sample, and determining a cell wall thickness of the sample based on the fiber image; Calculating standing wave effect characterization parameters for the plant to be extracted based on the cell wall thickness and the squeeze feedback force, and determining the standing wave effect tendency of the plant to be extracted based on the standing wave effect characterization parameters; The plant to be extracted is placed in an extraction tank and a solvent for leaching the Centella asiatica extract is added, and the extraction is assisted by ultrasound. The process parameters of the ultrasound-assisted extraction are controlled based on the standing wave effect tendency of the plant to be extracted, including adjusting the transmission power and transmission frequency of the ultrasound based on the standing wave effect characterization parameters, obtaining the image of the extraction tank liquid surface at the initial stage of leaching to extract the bubble density, calculating the cavitation effect uniformity characterization parameters in combination with the heat distribution discrete quantity of several detection points on the liquid surface of the extraction tank, determining whether there is an abnormality in the leaching process, and correcting the transmission power and transmission frequency of the ultrasound; Or, maintain the transmitting power and transmitting frequency of the ultrasonic wave to complete the leaching; The extract is filtered and chromatographically separated to obtain a Centella asiatica extract puree, which is separated and purified using a macroporous resin column and further purified and concentrated using an ultrafiltration technique, the purified and concentrated Centella asiatica extract puree is dried to obtain a Centella asiatica extract, and the Centella asiatica extract is mixed with a prefabricated toothpaste base mixture to obtain a toothpaste base.

[0007] Furthermore, the process of calculating the standing wave effect characterization parameters for the plant to be extracted includes: Calculating the ratio of the cell wall thickness to the preset standard cell wall thickness as the first standing wave effect characterization feature; The ratio of the squeeze feedback force to the preset standard squeeze feedback force is calculated as the characterization feature of the second standing wave effect; The standing wave effect characterization parameter is obtained by weighted summing the first standing wave effect characterization feature and the second standing wave effect characterization feature.

[0008] Further, determining the standing wave effect tendency of the plant to be extracted based on the standing wave effect characterization parameter includes: Tendency towards strong standing wave effect and tendency towards weak standing wave effect.

[0009] Furthermore, the process parameters of ultrasonic-assisted leaching are controlled based on the standing wave effect tendency of the plant to be extracted, including: Based on the standing wave effect characterization parameters, the ultrasonic emission power and emission frequency are adjusted, the leaching pool surface image at the initial stage of leaching is obtained to extract the bubble density, and the cavitation effect uniformity characterization parameters are calculated in combination with the thermal distribution discrete quantities of several detection points on the leaching pool surface to determine whether there is an abnormality in the leaching process, and the ultrasonic emission power and emission frequency are corrected. Alternatively, the ultrasonic transmission power and frequency are maintained to complete the leaching.

[0010] Furthermore, based on the standing wave effect characterization parameter, the ultrasonic emission power and the ultrasonic emission frequency are reduced, wherein the reduction amount of the ultrasonic emission power and the ultrasonic emission frequency is negatively correlated with the standing wave effect characterization parameter.

[0011] Furthermore, the process of calculating the characterization parameters for the uniformity of the cavitation effect includes: The ratio of the bubble density to the preset standard bubble density is calculated as the first cavitation effect uniformity characterization feature, the ratio of the heat distribution discrete amount to the preset standard heat distribution discrete amount is calculated as the second cavitation effect uniformity characterization feature, and the first cavitation effect uniformity characterization feature and the second cavitation effect uniformity characterization feature are weightedly summed to obtain the cavitation effect uniformity characterization parameter.

[0012] Furthermore, based on the cavitation effect uniformity characterization parameters, it is determined whether there is an abnormality in the leaching process, including: When the cavitation effect uniformity characterization parameter is less than the preset cavitation effect uniformity characterization parameter standard threshold value, it is determined that an abnormality exists in the leaching process.

[0013] Furthermore, when it is determined that there is an abnormality in the leaching process, the ultrasonic transmission power and the transmission frequency are increased based on the cavitation effect uniformity characterization parameters, wherein: The increase in the ultrasonic emission power and emission frequency is inversely proportional to the cavitation effect uniformity characterization parameter.

[0014] Furthermore, calculating the discrete quantities of heat distribution at a plurality of detection points on the liquid surface of the leaching tank comprises: The temperature of each detection point on the liquid surface of the leaching pool is determined by infrared temperature measuring equipment. The variance of each temperature value is calculated as the thermal distribution discrete quantity.

[0015] The present invention provides a mild toothpaste base, wherein the prefabricated toothpaste base mixture comprises: a whitening agent, a synergist, a tooth enamel repairing agent, a wetting agent, and an abrasive; The synergist includes: glyceryl glucoside, sodium hyaluronate, aloe vera, ectoine, acetyl glucosamine, white schizone gum, and milo wood extract; Humectants include: glycerin, propylene glycol.

[0016] Compared with the prior art, the beneficial effect of the present invention lies in that, in the process of using ultrasound to assist in the extraction of Centella asiatica extract, a standing wave effect is likely to occur. The thicker the plant cell wall used to extract the Centella asiatica extract and the greater the plant strength, the more likely the standing wave effect will occur. When the standing wave intensity is too large, the cell structure will be excessively destroyed, thereby affecting the integrity of the Centella asiatica extract molecules. The present invention comprehensively analyzes the difficulty of the standing wave effect in the plants currently used to extract plant extracts through the thickness of the plant cell wall and the extrusion feedback situation, thereby improving the control accuracy of the plant extract extraction process, and further reducing the ultrasonic emission power and emission frequency according to the analysis results, thereby reducing the standing wave effect and making the standing wave effect within a moderate range, which is beneficial to destroying the cell structure to release the plant extract and improve the extraction efficiency of the plant extract.

[0017] Furthermore, in the present invention, cavitation effect occurs during the extraction process of the Centella asiatica extract, and ultrasonic waves generate cavities and bubbles in the liquid, forming tiny liquid-air alternating zones, increasing the contact area between the solvent and the extract, and improving the chance of dissolution. The more bubbles there are during the extraction process, the stronger the cavitation effect is, and the higher the extraction efficiency is. In addition, the present invention takes into account the uniformity of the cavitation effect and characterizes the uniformity of the cavitation effect by the discrete amount of thermal distribution. The present invention comprehensively analyzes the degree of cavitation effect occurring during the extraction process by the bubble density and the discrete degree of temperature distribution in the extract, thereby improving the control accuracy for the current extraction process, and analyzing whether there is an abnormality in the entry and exit process based on the analyzed degree of cavitation effect. In the event of an abnormality, the ultrasonic emission power and emission frequency are increased, thereby enhancing the cavitation effect, improving the extraction efficiency of the plant extract, and further improving the preparation efficiency of the hair growth liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 The present invention is a flow chart of the method for preparing the mild toothpaste base; Figure 2 A flow chart for determining the standing wave effect tendency of the plant to be extracted; Figure 3 A flow chart for determining process parameters for controlling ultrasonic-assisted leaching; Figure 4 The figure is a flow chart for determining whether there is any abnormality in the leaching process. DETAILED DESCRIPTION

[0019] In order to make the objects and advantages of the present invention more clearly understood, the present invention is further described below in conjunction with embodiments; it should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0020] It should be pointed out that the data in this embodiment are obtained by comprehensive analysis and evaluation of the historical data of the system of the present invention in the six months before this determination and the corresponding historical determination results. It can be understood by those skilled in the art that the determination method of the system of the present invention for a single parameter mentioned above can be to select the value with the highest proportion as the preset standard parameter according to the data distribution, use weighted summation to use the obtained value as the preset standard parameter, substitute each historical data into a specific formula and use the value obtained by the formula as the preset standard parameter or other selection methods, as long as the system of the present invention can clearly define different specific situations in the single determination process through the obtained values.

[0021] The preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are only used to explain the technical principles of the present invention and are not intended to limit the protection scope of the present invention.

[0022] It should be noted that, in the description of the present invention, terms such as "up", "down", "left", "right", "inside" and "outside" indicating directions or positional relationships are based on the directions or positional relationships shown in the drawings. This is merely for the convenience of description and does not indicate or imply that the device or element must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it cannot be understood as a limitation on the present invention.

[0023] In addition, it should be noted that in the description of the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0024] See also Figure 1 As shown, it is a flow chart of the preparation method of the mild toothpaste base of the present invention.

[0025] The method for preparing a mild toothpaste base provided by an embodiment of the present invention comprises: Step S1, obtaining a sample of the plant to be extracted, and performing a property experiment on the sample, including squeezing the sample for a predetermined stroke, obtaining a squeezing feedback force, obtaining a fiber image of a tissue section of the sample, and determining a cell wall thickness of the sample based on the fiber image; Step S2, calculating a standing wave effect characterization parameter for the plant to be extracted based on the cell wall thickness and the extrusion feedback force, and determining a standing wave effect tendency of the plant to be extracted based on the standing wave effect characterization parameter; Step S3, placing the plant to be extracted into an extraction tank and adding a solvent for leaching the Centella asiatica extract, and performing ultrasonic-assisted leaching, and controlling the process parameters of the ultrasonic-assisted leaching based on the standing wave effect tendency of the plant to be extracted, including adjusting the transmission power and transmission frequency of the ultrasonic wave based on the standing wave effect characterization parameter, obtaining the liquid surface image of the extraction tank at the initial stage of leaching to extract the bubble density, calculating the cavitation effect uniformity characterization parameter in combination with the heat distribution discrete quantity of several detection points on the liquid surface of the extraction tank, determining whether there is an abnormality in the leaching process, and correcting the transmission power and transmission frequency of the ultrasonic wave; Or, maintain the transmitting power and transmitting frequency of the ultrasonic wave to complete the leaching; Step S4, filtering the leachate and performing chromatography separation to obtain Centella asiatica extract puree, using a macroporous resin column for separation and purification and further purifying and concentrating the Centella asiatica extract puree through ultrafiltration technology, drying the purified and concentrated Centella asiatica extract puree to obtain Centella asiatica extract, and mixing the Centella asiatica extract with a prefabricated toothpaste base mixture to obtain a toothpaste base.

[0026] Specifically, there is no specific limitation on the equipment for ultrasonic-assisted leaching. The equipment for emitting ultrasonic waves only needs to meet the requirements of adjustable transmission power and transmission frequency and be in line with the application environment. Technical personnel in this field can choose according to their needs.

[0027] It can be understood that the standing wave effect refers to a special wave phenomenon formed by the interference of waves when sound waves propagate and reflect in a liquid medium. This effect may lead to uneven distribution of ultrasonic energy in local areas during the extraction process, affecting the extraction efficiency and uniformity; In actual situations, plant properties, such as cell wall structure, tissue density, and chemical composition, may affect the propagation of ultrasound in the extraction medium, thereby affecting the formation and characteristics of standing waves.

[0028] In the process of ultrasonic-assisted extraction of anthocyanins in the present invention, a standing wave effect is likely to occur. The thicker the cell wall of the plant used to extract anthocyanins and the greater the plant strength, the more likely the standing wave effect will occur. When the standing wave intensity is too large, the cell structure will be excessively destroyed, thereby affecting the integrity of the anthocyanin molecules. The present invention comprehensively analyzes the difficulty of the standing wave effect in the plants currently used to extract anthocyanins through the thickness of the plant cell wall and the extrusion feedback situation, thereby improving the control accuracy of the anthocyanin extraction process, and further reduces the emission power and emission frequency of the ultrasonic wave according to the analysis results, thereby reducing the standing wave effect and making the standing wave effect within a moderate range, which is beneficial to destroying the cell structure to release anthocyanins and improve the extraction efficiency of anthocyanins.

[0029] Specifically, the process of calculating the standing wave effect characterization parameters for the plant to be extracted includes: Calculating the ratio of the cell wall thickness to the preset standard cell wall thickness as the first standing wave effect characterization feature; The ratio of the squeeze feedback force to the preset standard squeeze feedback force is calculated as the characterization feature of the second standing wave effect; The standing wave effect characterization parameter is obtained by weighted summing the first standing wave effect characterization feature and the second standing wave effect characterization feature.

[0030] Specifically, the sample is squeezed for a predetermined stroke to obtain the extrusion feedback force, which is the feedback force exerted on the device that squeezes the sample. In this embodiment, the sample can be squeezed by a small press. Of course, other forms can also be used, which will not be repeated here.

[0031] Specifically, in this embodiment, the preset standard cell wall thickness is obtained by pre-measurement, recording the cell wall thicknesses of several different plants that can be used to extract anthocyanins, and solving for the average cell wall thickness. The preset standard cell wall thickness is 0.7 to 0.85 times the average cell wall thickness.

[0032] Specifically, in this embodiment, the preset standard extrusion feedback force is obtained by pre-measurement, recording the extrusion feedback forces of several different plants that can be used to extract anthocyanins, and solving the average extrusion feedback force. The preset standard extrusion feedback force is 0.65 to 0.8 times the average extrusion feedback force.

[0033] See also Figure 2 As shown, it is a flow chart for determining the standing wave effect tendency of the plant to be extracted.

[0034] Specifically, determining the standing wave effect tendency of the plant to be extracted based on the standing wave effect characterization parameter includes: If the standing wave effect characterization parameter is greater than or equal to a preset standing wave effect characterization parameter standard threshold, then the plant to be extracted is determined to have a strong standing wave effect tendency; If the standing wave effect characterization parameter is less than the preset standing wave effect characterization parameter standard threshold, it is determined that the plant to be extracted has a weak standing wave effect tendency.

[0035] Specifically, the preset standing wave effect characterization parameter standard threshold is selected between the interval [1.2, 1.3].

[0036] See also Figure 3 As shown, it is a flow chart for determining the process parameters for controlling ultrasonic-assisted leaching.

[0037] Specifically, the process parameters for controlling ultrasonic-assisted leaching based on the standing wave effect tendency of the plant to be extracted include: If the plant to be extracted has a strong standing wave effect tendency, the ultrasonic emission power and emission frequency are adjusted based on the standing wave effect characterization parameters, the bubble density is extracted by obtaining the liquid surface image of the leaching pool at the initial stage of leaching, and the cavitation effect uniformity characterization parameters are calculated in combination with the thermal distribution discrete quantities of several detection points on the liquid surface of the leaching pool, to determine whether there is an abnormality in the leaching process, and to correct the ultrasonic emission power and emission frequency; If the plant to be extracted is prone to weak standing wave effect, the ultrasonic emission power and emission frequency are maintained to complete the leaching.

[0038] Specifically, the transmission power and the transmission frequency of the ultrasonic wave are reduced based on the parameters characterizing the standing wave effect, wherein the reduction amount of the transmission power and the transmission frequency of the ultrasonic wave is negatively correlated with the parameters characterizing the standing wave effect.

[0039] In this embodiment, optionally, the standing wave effect characterization parameter is compared with a preset first preset standing wave effect characterization parameter and a preset second preset standing wave effect characterization parameter. If the standing wave effect characterization parameter is less than or equal to the first preset standing wave effect characterization parameter, the first transmit power is reduced, and the first transmit power is 0.35 times the initial transmit power; If the standing wave effect characterization parameter is greater than the first preset standing wave effect characterization parameter and less than or equal to the second preset standing wave effect characterization parameter, then the second transmit power is reduced, and the second transmit power is 0.3 times the initial transmit power; If the standing wave effect characterization parameter is greater than the second preset standing wave effect characterization parameter, reducing the third transmit power, the third transmit power being 0.25 times the initial transmit power; Among them, the first preset standing wave effect characterization parameter is 1.2 times the preset standing wave effect characterization parameter standard threshold, and the second preset standing wave effect characterization parameter is 1.3 times the preset standing wave effect characterization parameter standard threshold.

[0040] Specifically, the process of calculating the characterization parameters for the uniformity of the cavitation effect includes: The ratio of the bubble density to the preset standard bubble density is calculated as the first cavitation effect uniformity characterization feature, the ratio of the heat distribution discrete amount to the preset standard heat distribution discrete amount is calculated as the second cavitation effect uniformity characterization feature, and the first cavitation effect uniformity characterization feature and the second cavitation effect uniformity characterization feature are weightedly summed to obtain the cavitation effect uniformity characterization parameter.

[0041] Specifically, in this embodiment, the preset standard bubble density is obtained by pre-measurement, recording the density of bubbles under several different ultrasonic emission powers, and solving the average value of the bubble density. The preset standard bubble density is 0.68 to 0.82 times the average value of the bubble density.

[0042] Specifically, in this embodiment, the preset standard thermal distribution discrete quantity is obtained by pre-measurement, recording the temperature values ​​at several detection points of the liquid surface of the leaching pool under several different ultrasonic transmission powers, calculating the variance of the temperature values ​​of each detection point of the liquid surface of the leaching pool under a single ultrasonic transmission power, and calculating the mean variance of the temperature values ​​of the liquid surface of the leaching pool under different ultrasonic transmission powers. The preset standard thermal distribution discrete quantity is 0.65 to 0.75 times the mean variance.

[0043] See also Figure 4 As shown, it is a flow chart for determining whether there is an abnormality in the leaching process.

[0044] Specifically, the cavitation effect uniformity characterization parameters are used to determine whether there are abnormalities in the leaching process, including: If the cavitation effect uniformity characterization parameter is greater than or equal to a preset cavitation effect uniformity characterization parameter standard threshold value, it is determined that there is no abnormality in the leaching process; If the cavitation effect uniformity characterization parameter is less than the preset cavitation effect uniformity characterization parameter standard threshold value, it is determined that there is an abnormality in the leaching process.

[0045] In the present invention, cavitation effect occurs during the extraction process of anthocyanins, and ultrasonic waves generate cavities and bubbles in the liquid, forming tiny liquid-air alternating zones, increasing the contact area between the solvent and the extracted substance, and improving the chance of dissolution. The more bubbles there are during the extraction process, the more uniform the temperature distribution, the stronger the cavitation effect, and the higher the extraction efficiency. The present invention comprehensively analyzes the degree of cavitation effect occurring during the extraction process through the bubble density and the temperature distribution discreteness in the extract, thereby improving the control accuracy for the current extraction process, and analyzing whether there is an abnormality in the entry and exit process based on the analyzed degree of cavitation effect. In the event of an abnormality, the ultrasonic emission power and emission frequency are increased, thereby enhancing the cavitation effect, improving the extraction efficiency of anthocyanins, and further improving the preparation efficiency of hair growth liquid.

[0046] Specifically, the preset cavitation effect uniformity characterization parameter standard threshold value Z0 is selected between the interval [1.15, 1.3].

[0047] Specifically, when it is determined that there is an abnormality in the leaching process, the ultrasonic transmission power and the transmission frequency are increased based on the cavitation effect uniformity characterization parameters, wherein: The increase in the ultrasonic emission power and emission frequency is inversely proportional to the cavitation effect uniformity characterization parameter.

[0048] In this embodiment, optionally, the cavitation effect uniformity characterization parameter standard threshold Za is compared with a preset first preset cavitation effect uniformity characterization parameter standard threshold Za1 and a preset second preset cavitation effect uniformity characterization parameter standard threshold Za2. If the cavitation effect uniformity characterization parameter standard threshold is less than or equal to the first preset cavitation effect uniformity characterization parameter standard threshold, increase the fourth transmit power, and the fourth transmit power is 0.35 times the initial transmit power; If the cavitation effect uniformity characterization parameter standard threshold is greater than the first preset cavitation effect uniformity characterization parameter standard threshold and less than or equal to the second preset cavitation effect uniformity characterization parameter standard threshold, then increase the fifth transmit power, and the fifth transmit power is 0.3 times the initial transmit power; If the cavitation effect uniformity characterization parameter standard threshold is greater than the second preset cavitation effect uniformity characterization parameter standard threshold, increase the sixth transmit power, and the sixth transmit power is 0.25 times the initial transmit power; Among them, the first preset cavitation effect uniformity characterization parameter standard threshold is 1.25 times the preset cavitation effect uniformity characterization parameter standard threshold, and the second preset cavitation effect uniformity characterization parameter standard threshold is 1.3 times the preset cavitation effect uniformity characterization parameter standard threshold.

[0049] Specifically, calculating the discrete quantities of heat distribution at several detection points on the liquid surface of the leaching tank includes: The temperature of each detection point on the liquid surface of the leaching pool is determined by infrared temperature measuring equipment. The variance of each temperature value is calculated as the thermal distribution discrete quantity.

[0050] Specifically, the prefabricated toothpaste base mixture includes: a whitening agent, a synergist, a tooth enamel repairing agent, a wetting agent, and an abrasive; The synergist includes: glyceryl glucoside, sodium hyaluronate, aloe vera, ectoine, acetyl glucosamine, white schizone gum, and milo wood extract; Humectants include: glycerin, propylene glycol.

[0051] So far, the technical solutions of the present invention have been described in conjunction with the preferred embodiments shown in the accompanying drawings. However, it is easy for those skilled in the art to understand that the protection scope of the present invention is obviously not limited to these specific embodiments. Without departing from the principle of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will fall within the protection scope of the present invention.

[0052] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A method for preparing a mild toothpaste base, characterized in that: include: Obtaining a sample of the plant to be extracted, and performing a property experiment on the sample, including squeezing the sample for a predetermined stroke, obtaining a feedback force of squeezing, obtaining a fiber image of a tissue section of the sample, and determining a cell wall thickness of the sample based on the fiber image; Calculating standing wave effect characterization parameters for the plant to be extracted based on the cell wall thickness and the squeeze feedback force, and determining the standing wave effect tendency of the plant to be extracted based on the standing wave effect characterization parameters; The plant to be extracted is placed in an extraction tank and a solvent for leaching the Centella asiatica extract is added, and ultrasonic-assisted leaching is performed. The process parameters of the ultrasonic-assisted leaching are controlled based on the standing wave effect tendency of the plant to be extracted, including: Based on the standing wave effect characterization parameters, the ultrasonic emission power and emission frequency are adjusted, the liquid surface image of the leaching pool at the initial stage of leaching is obtained to extract the bubble density, and the cavitation effect uniformity characterization parameters are calculated in combination with the thermal distribution discrete quantities of several detection points on the liquid surface of the leaching pool, to determine whether there is an abnormality in the leaching process, and to correct the ultrasonic emission power and emission frequency; Or, maintain the transmitting power and transmitting frequency of the ultrasonic wave to complete the leaching; The extract is filtered and chromatographically separated to obtain a Centella asiatica extract puree, which is separated and purified using a macroporous resin column and further purified and concentrated using an ultrafiltration technique, the purified and concentrated Centella asiatica extract puree is dried to obtain a Centella asiatica extract, and the Centella asiatica extract is mixed with a prefabricated toothpaste base mixture to obtain a toothpaste base.

2. The method for preparing a mild toothpaste base according to claim 1, characterized in that: The process of calculating the standing wave effect characterization parameters for the plant to be extracted includes: Calculating the ratio of the cell wall thickness to the preset standard cell wall thickness as the first standing wave effect characterization feature; The ratio of the squeeze feedback force to the preset standard squeeze feedback force is calculated as the characterization feature of the second standing wave effect; The standing wave effect characterization parameter is obtained by weighted summing the first standing wave effect characterization feature and the second standing wave effect characterization feature.

3. The method for preparing a mild toothpaste base according to claim 2, characterized in that: The determining the standing wave effect tendency of the plant to be extracted based on the standing wave effect characterization parameter comprises: Tendency towards strong standing wave effect and tendency towards weak standing wave effect.

4. The method for preparing a mild toothpaste base according to claim 3, characterized in that: The process parameters for controlling ultrasonic-assisted leaching based on the standing wave effect tendency of the plant to be extracted include: Based on the standing wave effect characterization parameters, the ultrasonic emission power and emission frequency are adjusted, the leaching pool surface image at the initial stage of leaching is obtained to extract the bubble density, and the cavitation effect uniformity characterization parameters are calculated in combination with the thermal distribution discrete quantities of several detection points on the leaching pool surface to determine whether there is an abnormality in the leaching process, and the ultrasonic emission power and emission frequency are corrected. Alternatively, the ultrasonic transmission power and frequency are maintained to complete the leaching.

5. The method for preparing a mild toothpaste base according to claim 1, characterized in that: Based on the standing wave effect characterization parameters, the ultrasonic transmission power and transmission frequency are reduced, where: The reduction of ultrasonic emission power and emission frequency is negatively correlated with the parameters characterizing the standing wave effect.

6. The method for preparing a mild toothpaste base according to claim 1, characterized in that: The process of calculating the characterization parameters for the uniformity of the cavitation effect includes: The ratio of the calculated bubble density to the preset standard bubble density is used as the first cavitation effect uniformity characterization feature. The ratio of the heat distribution discrete quantity to the preset standard heat distribution discrete quantity is calculated as the characterization feature of the uniformity of the second cavitation effect. The cavitation effect uniformity characterization parameter is obtained by weighted summing the first cavitation effect uniformity characterization feature and the second cavitation effect uniformity characterization feature.

7. The method for preparing a mild toothpaste base according to claim 1, characterized in that: Determine whether there is abnormality in the leaching process based on the cavitation effect uniformity characterization parameters, including: When the cavitation effect uniformity characterization parameter is less than the preset cavitation effect uniformity characterization parameter standard threshold value, it is determined that an abnormality exists in the leaching process.

8. The method for preparing a mild toothpaste base according to claim 7, characterized in that: When it is determined that there is an abnormality in the leaching process, the ultrasonic transmission power and the transmission frequency are increased based on the cavitation effect uniformity characterization parameters, wherein: The increase in the ultrasonic emission power and emission frequency is inversely proportional to the cavitation effect uniformity characterization parameter.

9. The method for preparing a mild toothpaste base according to claim 1, characterized in that: Calculating the discrete quantities of heat distribution at a plurality of detection points on the liquid surface of the leaching tank, including: The temperature of each detection point on the liquid surface of the leaching pool is determined by infrared temperature measuring equipment. The variance of each temperature value is calculated as the thermal distribution discrete quantity.

10. A mild toothpaste base for implementing the method according to any one of claims 1 to 9, characterized in that: The prefabricated toothpaste base mixture includes: a whitening agent, a synergist, a tooth enamel repairing agent, a wetting agent, and an abrasive; The synergist includes: glyceryl glucoside, sodium hyaluronate, aloe vera, ectoine, acetyl glucosamine, white schizone gum, and milo wood extract; Humectants include: glycerin, propylene glycol.

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