A microneedle patch punching, rolling, cutting, tearing, and pasting machine

Abstract

The present invention provides a punching, cutting, tearing and pasting machine for microneedle patches, which belongs to the technical field of microneedle patch production equipment. It solves the problem of low yield rate caused by the accumulation of alignment errors in existing microneedle patch processing equipment after long-term production. The punching, cutting, tearing and pasting machine for microneedle patches includes a frame, a cutting roller knife seat is provided on the frame, a bottom roller and a cutting roller are rotatably connected to the cutting roller knife seat, and a composite film can pass through and cut between the bottom roller and the cutting roller. The cutting roller has multiple groups of roller blade groups arranged along the circumference of the cutting roller and multiple pairs of connecting roller knives arranged along the circumference of the cutting roller, each group of roller blade groups includes waist-shaped roller blade one, roller blade two and roller blade three, and the roller blade one of the same group is located in the inner circle of roller blade two. The punching, cutting, tearing and pasting machine for microneedle patches avoids the accumulation of alignment errors during the long-term production process, and ensures the high yield rate of microneedle patches after long-term production.

Description

Technical Field

[0001] The invention belongs to the technical field of microneedle patch production devices and relates to a punching, rolling, cutting, tearing, discarding and pasting integrated machine for microneedle patches. Background Art

[0002] like Figure 1 As shown, the microneedle patch is punched out from the soluble microneedle original sheet into a plurality of arc-shaped soluble microneedle sheets 2, and then the release paper layer 9 and the adhesive layer 10 of the composite film 1 are roll-cut, and after roll-cutting, the half-cut release paper waste ring is torn off by rotating the waste winding roller, and the cut composite film 1 is connected with a waist-shaped waist-shaped sheet 8, and the inner edge of the adhesive layer 10 of the waist-shaped sheet 8 has an inner adhesive surface 101, and the inner adhesive surface 101 is exposed, and the waist-shaped sheet 8 is provided with a make-way opening 91 opened along its own length direction at the left and right ends of the release paper layer 9, and then the cut soluble microneedle sheet 2 is placed on the waist-shaped sheet 8 by a robot, so that the soluble microneedle sheet 2 is bonded to the exposed adhesive on the inner edge of the waist-shaped sheet 8, thereby forming a microneedle patch.

[0003] Therefore, the existing roller-sticking integrated machine needs to cut the microneedle original sheet and roll-cut the composite film. For example, Chinese patent application [Authorization Announcement No.: CN113548511B] discloses a microneedle eye patch processing equipment, including an eye patch sheeting machine and an eye patch conveyor. The eye patch conveyor is arranged at the discharge end of the eye patch sheeting machine, and the eye patch sheeting machine includes a sheeting machine frame provided with a plurality of material belt discharge shafts and a waste material winding shaft. From one end to the other end of the sheeting machine frame, a first traction compound device, a microneedle original sheet transfer device, a traction conveying device, a microneedle original sheet die-cutting device, a first low-viscosity film waste collection device, a medical adhesive tape die-cutting device, a second traction compound device and a second low-viscosity film waste collection device are arranged in sequence. The material belt discharge shaft includes a first low-viscosity film discharge shaft, a waste tape discharge shaft, and a second low The mucosal discharge shaft and the medical adhesive tape discharge shaft, the waste winding shaft includes a microneedle original sheet waste winding shaft, a first low-mucosal waste winding shaft, a medical adhesive waste winding shaft, a release mold winding shaft and a second low-mucosal waste winding shaft, the first traction composite device includes a first composite knife seat installed on the sheet making machine frame, the first composite knife seat is rotatably mounted with a first composite stick and a first composite rubber roller driven by a first driving device, the roller surface of the first composite rubber roller is arranged against the roller surface of the first composite stick, the microneedle original sheet transfer device includes an original sheet loading base platform installed on the sheet making machine frame, the original sheet loading base platform is provided with an adhesive pallet and an original sheet moving mechanism for transferring and placing the microneedle original sheet on the adhesive pallet, and an original sheet loading mechanism for realizing microneedle original sheet loading is provided upstream of the original sheet moving mechanism.

[0004] The above structure is to cut the microneedle original sheet of the first low-viscosity film tape by the first cutting knife seat to form a number of eye patch sheets after cutting, and the second cutting knife seat forms a medical adhesive sheet by roller cutting the composite film of the release paper and the adhesive backing, and then the eye patch sheet is pasted on the block-shaped medical adhesive sheet. The two need to maintain the same pulling speed and tension when pasting, but during long-term production, the pulling speed and tension will gradually produce errors, resulting in the error between the eye patch sheet and the medical adhesive sheet continuing to increase, reducing the yield of long-term production and affecting the normal production efficiency of the microneedle patch. Summary of the invention

[0005] The purpose of the present invention is to address the above-mentioned problems in the prior art and to propose a microneedle patch punching roller cutting, tearing, and pasting all-in-one machine. The technical problem to be solved by the present invention is: how to solve the problem of low yield caused by the accumulation of positioning errors of existing microneedle patch processing equipment after long-term production.

[0006] The purpose of the present invention can be achieved by the following technical solutions:

[0007] The cutting roller of the present invention is a kind of integrated machine for cutting, tearing and pasting microneedle patches, comprising a frame, a cutting roller seat is provided on the frame, a bottom roller and a cutting roller are rotatably connected to the cutting roller seat, and a composite film can pass through and cut the bottom roller and the cutting roller, and the composite film is characterized in that the cutting roller is provided with a plurality of roller blade groups arranged along the circumference of the cutting roller and a plurality of connecting roller blades arranged along the circumference of the cutting roller, each group of roller blade groups comprises a waist-shaped roller blade one, a roller blade two and a roller blade three, the roller blade one of the same group is located in the inner circle of the roller blade two, the roller blade two of the same group is located in the inner circle of the roller blade three, both ends of the roller blade two are provided with openings, the end portions of the connecting roller blade connect the opening walls of the roller blade two in the two adjacent roller blade groups, the middle part of the connecting roller blade intersects with the corresponding roller blade three, the roller blade three is provided with a reserved notch on the blade edge at the intersection with the connecting roller blade, and the cutting edge height of the roller blade two is lower than the cutting edge height of the roller blade one and the roller blade three.

[0008] When the composite film of the microneedle patch is cut, the present application only uses a group of cutting roller knife seats to cut the composite film, and roller blade one cuts the inner hole of the composite film. After cutting, in order to reserve space on the inner side of the back glue for the soluble microneedle sheet to fit, the height of roller blade two is set to be lower than the heights of roller blade one and roller blade three, so that during the cutting process, roller blade one and roller blade three directly cut the composite film as a whole, and roller blade two cuts the release paper layer on the composite film, leaving a circle on the inner side of the back glue. In order to quickly peel off the annular waste ring after cutting, a connecting roller knife is provided, which also realizes cutting the release paper layer on the composite film, realizes connecting two adjacent waste rings to form cut waste, and realizes that the cut waste can be directly pulled out when peeling, which is convenient for cutting. In order to realize that multiple waist-shaped pieces can be connected to the composite film as a whole after cutting, so as to facilitate the next step and the pasting and cutting of soluble waist-shaped pieces, two reserved notches are provided at the intersection of roller blade three and connecting roller knife, so that the cut waist-shaped pieces can be connected to the composite film through the uncut parts of the reserved notches, so that the composite film can be cut at one time, and the problem of large errors occurring during long-term use after multiple cutting and alignment is avoided. The present application is carried out through one-time cutting, and in order to facilitate the subsequent tearing of waste materials, pasting and cutting after cutting, a reserved notch is also reserved, so that the cut waist-shaped pieces can be stably connected to the composite film as a whole through the uncut parts of the reserved notches, so as to avoid falling directly from the composite film, so as to facilitate the subsequent tearing of waste materials, pasting and cutting of the composite film.

[0009] The present application is to cut the composite film at one time by setting a plurality of roller blades with different cutting edge heights. In order to facilitate the rapid pulling out of the waste ring during cutting, a connecting roller knife is additionally provided. In order to facilitate the connection of the waist-shaped sheet with the composite film as a whole after cutting, and to facilitate the subsequent tearing of waste materials, pasting and unloading, a reserved notch is reserved at the intersection of the roller blade three and the connecting roller knife to achieve connection and facilitate unloading, thereby avoiding the accumulation of alignment errors during a long production process and ensuring a high yield of microneedle patches after long-term production.

[0010] In the above-mentioned microneedle patch punching, roller cutting, tearing, scrapping and pasting integrated machine, the reserved gaps are all located between a corresponding pair of connecting roller cutters, and the mouth wall on one side of the reserved gap is the side wall of the corresponding connecting roller cutter.

[0011] The reserved gap is opened between the two connecting roller cutters so that the two reserved gaps at one end of the same waist-shaped piece are closer, and for the convenience of processing, the side wall of the connecting roller cutter is directly used as the mouth wall of one side of the reserved gap, making processing more convenient.

[0012] In the above-mentioned integrated machine for punching, rolling, cutting, tearing, and pasting microneedle patches, the cutting edge height of the connecting roller blade is equal to the cutting edge height of the second roller blade.

[0013] The arrangement of this structure enables the connecting roller knife and the second roller blade to cut the release paper layer on the composite film without cutting the adhesive layer, thereby ensuring the stability of the cutting roller arrangement.

[0014] In the above-mentioned punching, roller cutting, tearing, scrapping and pasting machine for the microneedle patch, each pair of connecting roller knives is arranged in parallel, and the connecting roller knives are integrally formed with the corresponding roller blade two and roller blade three.

[0015] The connecting roller cutters are arranged in parallel, so that two adhesive portions are reserved on the left and right sides of the microneedle patch, making the left and right ends of the waist-shaped patch more uniform, further improving the stability after cutting.

[0016] In the above-mentioned punching, rolling, cutting, tearing, and pasting machine for the microneedle patch, the diameter of the reserved notch is 0.1 mm to 0.9 mm.

[0017] By setting the size of the reserved notch, the reserved notch can ensure that the waist-shaped piece can be stably connected to the composite film after cutting, and can also facilitate the subsequent rapid cutting of the connection during the unloading process, thereby improving the convenience of unloading.

[0018] In the present application, the size of the reserved gap is preferably 0.3 mm to 0.6 mm.

[0019] In the above-mentioned microneedle patch punching roller cutting, tearing, and pasting machine, two guide rods distributed up and down are connected to the same side of the cutting roller knife seat, and the gap between the cutting roller and the bottom roller is located between the two guide rods. The guide rod located above can tension and guide the cut waste, and the guide rod located below can tension and guide the cut composite film.

[0020] The setting of the guide rod is convenient for tensioning and guiding the cut waste, and can also tension and guide the cut composite film, so as to facilitate further processing of the cut waste and the cut composite film.

[0021] In the above-mentioned microneedle patch punching roller cutting, tearing, waste pasting integrated machine, the frame is connected with a composite film input roller, a waste winding roller and a soluble microneedle sheet pasting unloading platform, the composite film input roller is arranged obliquely above the front end of the cutting roller knife seat, the waste winding roller and the soluble microneedle sheet pasting unloading platform are both located at the rear end of the cutting roller knife seat, the upper guide rod is arranged obliquely below the waste winding roller, and the lower guide rod is arranged obliquely above the soluble microneedle sheet pasting unloading platform.

[0022] By locating the waste winding roller obliquely below the guide rod and the soluble microneedle sheet pasting unloading platform obliquely below the guide rod, it is convenient to tension the cut waste and the cut composite film, and the upper and lower arrangements can achieve the tensioning of the corresponding cut waste and the composite film in opposite directions during the winding process, thereby improving the tensioning effect of the cut waste and the composite film.

[0023] In the above-mentioned microneedle patch punching, roller cutting, tearing, and pasting machine, the frame is connected to a truss robot that can grab the soluble microneedle sheet and move it to the waist-shaped sheet, the front and rear ends of the soluble microneedle sheet pasting unloading table are fixedly connected to support rollers that can horizontally tension the cut composite film, and the soluble microneedle sheet pasting unloading table is also hinged with a unloading tray that can suck the waist-shaped sheet, and the truss robot can push the soluble microneedle sheet to drive the waist-shaped sheet to move downward until it is pressed on the unloading tray.

[0024] The cut composite film is horizontally tensioned by support rollers on the soluble microneedle sheet pasting unloading table. The truss manipulator grabs the cut soluble microneedle sheet and drives the soluble microneedle sheet to move to the inner bonding surface of the back adhesive layer of the waist-shaped sheet and fits it with the exposed inner bonding surface. Due to the provision of an unloading tray, the unloading tray can directly suck the waist-shaped sheet together during the pressing and fitting process of the truss manipulator. The truss manipulator and the unloading tray synchronously drive the cut waist-shaped sheet to move downward, and the cut composite film is still tensioned by support rollers. Therefore, the connection between the waist-shaped sheet and the cut composite film can be quickly broken, so that the soluble microneedle sheet can be laminated and unloaded through the cooperation of the truss manipulator and the unloading tray, thereby improving the production efficiency of the microneedle patch.

[0025] In the above-mentioned microneedle patch punching, tearing, and pasting machine, the soluble microneedle patch pasting unloading table has two support plates arranged horizontally opposite to each other, the unloading tray is arranged between the two support plates, and the end of the support roller is arranged at the upper end of the support plate.

[0026] By setting the unloading plate between two support plates and the support roller connected to the upper end of the support plate, the unloading plate is always located below the cut composite film during the unloading process. The waist-shaped piece on the cut composite film needs to be pressed down by a truss manipulator to achieve the suction of the waist-shaped piece, thereby increasing the pulling force on the waist-shaped piece during unloading and thus improving the stability of unloading.

[0027] A plurality of suction holes are provided on the unloading tray, and a cylinder which can control the suction of the suction holes is provided on the unloading table for pasting the soluble microneedle sheet. The unloading material vacuum-adsorbs the waist-shaped sheet onto the upper end surface of the unloading tray through the suction holes, and the cylinder is closed to release the suction of the waist-shaped sheet by the unloading tray.

[0028] In the above-mentioned microneedle patch punching, roller cutting, tearing, and pasting machine, a feeding shaft is hinged on the soluble microneedle patch pasting feeding table, and the middle protrusion of the feeding shaft forms a connecting part to which the feeding tray can be fixedly connected, and the front end of the lower end surface of the feeding tray is fixedly connected to the connecting part.

[0029] By fixing the front end of the lower end surface of the unloading tray to the connecting part, when the unloading shaft rotates, the front end of the unloading tray can be driven to swing downward, so as to complete the unloading of the waist-shaped piece and improve the unloading efficiency.

[0030] Here, a feeding cylinder is arranged on the feeding table for pasting the soluble microneedle sheet. The feeding cylinder drives the feeding shaft, and the feeding shaft drives the feeding plate to flip, thereby achieving feeding.

[0031] Compared with the prior art, the microneedle patch punching, rolling, tearing, and pasting machine has the following advantages:

[0032] 1. The composite film is cut at one time by setting a plurality of roller cutters with different blade heights. In order to facilitate the rapid pulling out of the cut waste during cutting, a connecting roller cutter is additionally provided. In order to facilitate the connection of the waist-shaped sheet with the composite film as a whole after cutting, and to facilitate the subsequent rapid unloading, a reserved notch is only reserved at the intersection of the roller blade three and the connecting roller cutter to achieve connection and facilitate unloading, thereby avoiding large errors in the long-term production process, and also facilitating subsequent processing and unloading, ensuring that the microneedle patch has a high yield rate and is convenient and quick to unload during the long-term production process.

[0033] 2. Due to the provision of a feed tray, during the process of the truss manipulator pressing down and laminating, the feed tray can directly absorb the cut waist-shaped sheet, and the truss manipulator and the feed tray synchronously drive the cut waist-shaped sheet to move downward, while the cut composite film is still tensioned by the support roller, so that the connection between the waist-shaped sheet and the cut composite film can be quickly broken, so that the soluble microneedle sheet can be laminated and the feed tray can be used to achieve feed unloading, thereby improving the production efficiency of the waist-shaped sheet. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 It is a schematic diagram of the structure of the existing composite film after cutting and the soluble microneedle sheet.

[0035] Figure 2 It is a structural schematic diagram of the punching, rolling, cutting, tearing, and pasting all-in-one machine for the microneedle patch.

[0036] Figure 3 It is a partial cross-sectional view of the punching, rolling, cutting, tearing, and pasting all-in-one machine for the microneedle patch.

[0037] Figure 4 It is a structural schematic diagram of a cutting roller in a punching roller cutting, tearing, and pasting all-in-one machine for a microneedle patch.

[0038] Figure 5 yes Figure 4 A partial enlarged view of point A in the middle.

[0039] Figure 6 It is a structural schematic diagram of a cutting roller knife seat in a punching roller cutting, tearing, scrapping and pasting all-in-one machine for a microneedle patch.

[0040] Figure 7 It is one of the structural schematic diagrams of the soluble microneedle patch pasting feed table in the punching, rolling, cutting, tearing, and pasting all-in-one machine of the microneedle patch.

[0041] Figure 8 This is the second structural schematic diagram of the soluble microneedle patch pasting feed station in the punching, rolling, cutting, tearing, and pasting all-in-one machine for the microneedle patch.

[0042] In the figure, 1. composite film; 2. soluble microneedle sheet; 3. frame; 31. composite film input roller; 32. waste winding roller; 33. truss manipulator; 4. cutting roller knife seat; 41. guide rod; 5. bottom roller; 6. cutting roller; 61. roller blade group; 61a. roller blade one; 61b. roller blade two; 61b1. opening; 61c. roller blade three; 61c1. reserved gap; 62. connecting roller knife; 7. soluble microneedle sheet pasting unloading platform; 71. support roller; 72. unloading tray; 73. support plate; 74. unloading shaft; 74a. connecting part; 8. waist-shaped sheet; 9. release paper layer; 91. clearance opening; 10. adhesive layer; 101. inner adhesive surface. DETAILED DESCRIPTION

[0043] The following are specific embodiments of the present invention and the accompanying drawings to further describe the technical solution of the present invention, but the present invention is not limited to these embodiments.

[0044] like Figure 2 As shown, the punching, roller cutting, tearing, and pasting machine of the microneedle patch includes a frame 3, on which is provided a cutting roller knife seat 4, on which a bottom roller 5 and a cutting roller 6 are rotatably connected, and between the bottom roller 5 and the cutting roller 6 a composite film 1 can pass and cut.

[0045] Specifically, Figure 2-8As shown, the cutting roller 6 has a plurality of roller blade groups 61 arranged along the circumference of the cutting roller 6 and a plurality of pairs of connecting roller blades 62 arranged along the circumference of the cutting roller 6. Each roller blade group 61 includes a waist-shaped roller blade 1 61a, a roller blade 2 61b and a roller blade 3 61c. The roller blade 1 61a of the same group is located in the inner circle of the roller blade 2 61b, and the roller blade 2 61b of the same group is located in the inner circle of the roller blade 3 61c. Both ends of the roller blade 2 61b are provided with openings 61b1, and the connecting roller blades 62 are connected to the roller blade 2 61b. The end portions of the roller cutter 62 connect the opening walls of the roller blade 2 61b of the two adjacent roller blade groups 61, and the middle part of the connected roller cutter 62 intersects with the corresponding roller blade 3 61c. The roller blade 3 61c is provided with a reserved notch 61c1 on the blade at the intersection with the connected roller cutter 62. The cutting edge height of the roller blade 2 61b is lower than the cutting edge height of the roller blade 1 61a and the roller blade 3 61c, and the diameter of the reserved notch 61c1 is 0.1mm to 0.9mm.

[0046] When the composite film 1 of the microneedle patch is cut, the present application only uses a group of cutting roller blade seats 4 to cut the composite film 1, and the roller blade 1 61a cuts the inner hole of the composite film 1. After cutting, in order to reserve space on the inner side of the back glue for the soluble microneedle sheet 2 to fit, the height of the roller blade 2 61b is set to be lower than the heights of the roller blade 1 61a and the roller blade 3 61c, so that during the cutting process, the roller blade 1 61a and the roller blade 3 61c directly cut the composite film 1 as a whole, and the roller blade 2 61b cuts the release paper layer 9 on the composite film 1, leaving a circle on the inner side of the back glue. In order to quickly peel off the annular waste ring after cutting, a connecting roller blade 62 is provided, which also cuts the release paper layer 9 on the composite film 1, thereby connecting two adjacent waste rings to form cut waste, and achieving that the cut waste can be directly pulled out when peeling, which is convenient for cutting waste. In order to achieve multiple The cut waist-shaped sheet 8 can be connected to the composite film 1 as a whole, which is convenient for the next step and the pasting and cutting of the soluble microneedle sheet 2. Therefore, two reserved notches 61c1 are set at the intersection of the roller blade three 61c and the connecting roller knife 62, so that the cut waist-shaped sheet 8 can be connected to the composite film 1 through the uncut part of the reserved notch 61c1, so that the composite film 1 can be cut at one time, avoiding the problem of large errors in long-term use after multiple cutting and alignment. The present application is a one-time cutting, and in order to facilitate the subsequent tearing of waste materials, pasting and cutting after cutting, a reserved notch 61c1 is also reserved, so that the cut waist-shaped sheet 8 can be stably connected to the composite film 1 as a whole through the uncut part of the reserved notch 61c1, avoiding falling directly from the composite film 1, facilitating the subsequent tearing of waste materials, pasting and cutting of the composite film 1, ensuring that the yield of the microneedle patch is high and the cutting is convenient and quick during the long production process.

[0047] The present application is to cut the composite film 1 at one time by setting a plurality of roller blades with different cutting edge heights. In order to facilitate the rapid pulling out of the waste ring during cutting, a connecting roller knife 62 is additionally provided. In order to facilitate the connection of the waist-shaped sheet 8 with the composite film 1 as a whole after cutting, and to facilitate the subsequent tearing of waste materials, pasting and unloading, a reserved notch 61c1 is reserved at the intersection of the roller blade three 61c and the connecting roller knife 62 to achieve connection and facilitate unloading, thereby avoiding large errors in the long-term production process, and also facilitating the subsequent tearing of waste materials, pasting and unloading, thereby ensuring a high yield of microneedle patches after long-term production.

[0048] like Figure 4 and Figure 5 As shown, the reserved notches 61c1 are all located between the corresponding pair of connecting roller cutters 62, the mouth wall on one side of the reserved notch 61c1 is the side wall of the corresponding connecting roller cutter 62, the cutting edge height of the connecting roller cutter 62 is equal to the cutting edge height of roller blade two 61b, the two connecting roller cutters 62 of each group of connecting roller cutters 62 are arranged in parallel, and the connecting roller cutters 62 are integrally formed with the corresponding roller blade two 61b and roller blade three 61c.

[0049] like Figure 2 , Figure 3 , Figure 5 and Figure 6 As shown, two guide rods 41 distributed up and down are connected to the same side of the cutting roller holder 4, the gap between the cutting roller 6 and the bottom roller 5 is located between the two guide rods 41, the upper guide rod 41 can tension and guide the cut waste, and the lower guide rod 41 can tension and guide the cut composite film 1, and the frame 3 is connected with a composite film input roller 31, a waste winding roller 32 and a soluble microneedle sheet pasting unloading platform 7, the composite film input roller 31 is arranged obliquely above the front end of the cutting roller holder 4, the waste winding roller 32 and the soluble microneedle sheet pasting unloading platform 7 are both located at the rear end of the cutting roller holder 4, the upper guide rod 41 is arranged obliquely below the waste winding roller 32, and the lower guide rod 41 is arranged obliquely above the soluble microneedle sheet pasting unloading platform 7.

[0050] like Figure 2 , Figure 3 , Figure 6 and Figure 7As shown, the frame 3 is connected with a truss manipulator 33 which can grab and move the soluble microneedle sheet 2 onto the waist-shaped sheet 8, the front and rear ends of the soluble microneedle sheet pasting unloading platform 7 are fixedly connected with support rollers 71 which can horizontally tension the cut composite film 1, and the soluble microneedle sheet pasting unloading platform 7 is also hinged with an unloading plate 72 which can absorb the waist-shaped sheet 8, and the truss manipulator 33 can push the soluble microneedle sheet 2 to drive the waist-shaped sheet 8 to move downward to press on the unloading plate On the plate 72, the soluble microneedle sheet pasting unloading platform 7 has two support plates 73 arranged horizontally opposite to each other, the unloading plate 72 is arranged between the two support plates 73, the end of the support roller 71 is arranged at the upper end of the support plate 73, and the soluble microneedle sheet pasting unloading platform 7 is hinged with a unloading shaft 74, and the middle part of the unloading shaft 74 is convex to form a connecting part 74a to which the unloading plate 72 can be fixedly connected, and the front end of the lower end surface of the unloading plate 72 is fixedly connected to the connecting part 74a.

[0051] The specific embodiments described herein are merely examples of the spirit of the present invention. Those skilled in the art may make various modifications or additions to the specific embodiments described or replace them in similar ways, but they will not deviate from the spirit of the present invention or exceed the scope defined by the appended claims.

Claims

1. A microneedle patch punching, rolling, cutting, tearing, and pasting machine, comprising a frame (3), a cutting roller holder (4) being provided on the frame (3), a bottom roller (5) and a cutting roller (6) being rotatably connected to the cutting roller holder (4), a space between the bottom roller (5) and the cutting roller (6) being provided for a composite film (1) to pass through and cut, and characterized in that: The cutting roller (6) has a plurality of roller blade groups (61) arranged along the circumference of the cutting roller (6) and a plurality of pairs of connecting roller blades (62) arranged along the circumference of the cutting roller (6), each roller blade group (61) comprising a waist-shaped roller blade one (61a), a roller blade two (61b) and a roller blade three (61c), the roller blade one (61a) of the same group is located within the inner circle of the roller blade two (61b), the roller blade two (61b) of the same group is located within the inner circle of the roller blade three (61c), both ends of the roller blade two (61b) are provided with openings (61b1), and the connecting roller blade (62) is provided with a plurality of roller blade groups (61a) and a plurality of roller blade groups (61b) arranged along the circumference of the cutting roller (6). The two end portions of the connecting roller blade (62) connect the opening (61b1) of the roller blade two (61b) in the two adjacent roller blade groups (61), the middle portion of the connecting roller blade (62) intersects with the corresponding roller blade three (61c), and the roller blade three (61c) is provided with a reserved notch (61c1) on the blade at the intersection with the connecting roller blade (62), the edge height of the roller blade two (61b) is lower than the edge height of the roller blade one (61a) and the roller blade three (61c), and the edge height of the connecting roller blade (62) is equal to the edge height of the roller blade two (61b).

2. The microneedle patch punching, rolling, tearing, and pasting integrated machine according to claim 1, characterized in that: The reserved notches (61c1) are each located between a corresponding pair of connecting roller cutters (62), and an opening wall on one side of the reserved notches (61c1) is a side wall of the corresponding connecting roller cutter (62).

3. The microneedle patch punching, rolling, tearing, and pasting integrated machine according to claim 1 or 2, characterized in that: Each pair of connecting roller blades (62) is arranged in parallel, and the connecting roller blades (62) are integrally formed with the corresponding roller blade two (61b) and roller blade three (61c).

4. The microneedle patch punching, rolling, tearing, and pasting integrated machine according to claim 1 or 2, characterized in that: The diameter of the reserved notch (61c1) is 0.1 mm to 0.9 mm.

5. The microneedle patch punching, rolling, tearing, and pasting integrated machine according to claim 1 or 2, characterized in that: The same side of the cutting roller knife seat (4) is connected to two guide rods (41) distributed in an upper and lower direction, the gap between the cutting roller (6) and the bottom roller (5) is located between the two guide rods (41), the upper guide rod (41) can tension and guide the cut waste, and the lower guide rod (41) can tension and guide the cut composite film (1).

6. The microneedle patch punching, rolling, tearing, and pasting integrated machine according to claim 5, characterized in that: The frame (3) is connected to a composite film input roller (31), a waste material winding roller (32) and a soluble microneedle sheet pasting unloading platform (7); the composite film input roller (31) is arranged obliquely above the front end of the cutting roller blade seat (4); the waste material winding roller (32) and the soluble microneedle sheet pasting unloading platform (7) are both located at the rear end of the cutting roller blade seat (4); the guide rod (41) located above is arranged obliquely below the waste material winding roller (32); and the guide rod (41) located below is arranged obliquely above the soluble microneedle sheet pasting unloading platform (7).

7. The microneedle patch punching, rolling, tearing, and pasting integrated machine according to claim 6, characterized in that: The frame (3) is connected to a truss manipulator (33) capable of grabbing the soluble microneedle sheet (2) and moving it onto the waist-shaped sheet (8); the front and rear ends of the soluble microneedle sheet pasting unloading platform (7) are fixedly connected to support rollers (71) capable of horizontally tensioning the cut composite film (1); the soluble microneedle sheet pasting unloading platform (7) is also hingedly provided with an unloading plate (72) capable of sucking the waist-shaped sheet (8); the truss manipulator (33) can push the soluble microneedle sheet (2) to drive the waist-shaped sheet (8) to move downward until it is pressed on the unloading plate (72).

8. The microneedle patch punching, rolling, tearing, and pasting integrated machine according to claim 7, characterized in that: The soluble microneedle sheet pasting unloading platform (7) has two support plates (73) arranged transversely opposite to each other, the unloading tray (72) is arranged between the two support plates (73), and the end of the support roller (71) is arranged on the upper end of the support plate (73).

9. The microneedle patch punching, rolling, tearing, and pasting integrated machine according to claim 7, characterized in that: A feeding shaft (74) is hingedly connected to the soluble microneedle sheet pasting feeding platform (7), a middle protrusion of the feeding shaft (74) forms a connecting portion (74a) to which the feeding tray (72) can be fixedly connected, and the front end of the lower end surface of the feeding tray (72) is fixedly connected to the connecting portion (74a).

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