Composition containing lutein ester and zeaxanthin for promoting eye health

Abstract

The invention discloses a health-care composition, and belongs to the field of health-care foods. Every 1000 mL of the composition contains 1.7 to 1.9 g of lutein ester, 0.52 to 0.61 g of zeaxanthin, 0.35 to 0.47 g of astaxanthin, 30 to 60 g of a chrysanthemum extract, 40 to 70 g of celery powder, 30 to 60 g of Lithocarpus litseifolius powder, 110 to 130 g of a sweetening agent and the balance of purified water. According to the composition provided by the invention, all the raw materials are compounded for use, so that a remarkable asthenopia relieving effect is achieved, and eye health is favorably promoted.

Description

Technical Field

[0001] The present application relates to the field of health food, and in particular to a composition containing lutein ester and zeaxanthin for promoting eye health. Background Art

[0002] With the change of modern lifestyle, people rely more and more on electronic screens such as computers, smartphones and other digital devices, which leads to increasingly serious problems of eyestrain.

[0003] Eye strain is usually caused by:

[0004] 1. Dry eyes caused by insufficient tear secretion and decreased retinal function due to prolonged staring at the screen or close-up use of the eyes;

[0005] 2. Long-term use of the eyes leads to a decline in the focusing and adjustment function, causing refractive eye diseases such as myopia, hyperopia or astigmatism;

[0006] 3. Ageing or chronic diseases lead to increased intraocular pressure, increasing the risk of glaucoma;

[0007] 4. Prolonged exposure to strong light or blue light, or aging of the body can cause irreversible damage to the lens, leading to lens aging and the formation of cataracts.

[0008] At present, most of the products for relieving visual fatigue caused by the above reasons are medicines or non-pure Chinese medicine preparations containing compounds, and most consumers have a certain resistance to the use of medicines. Therefore, it is of great significance to provide a health product that is a pure plant extract non-Chinese medicine product that can relieve visual fatigue. Summary of the invention

[0009] The purpose of the present invention is to provide a composition for promoting eye health containing lutein ester and zeaxanthin, which is compounded with plant ingredients, has high safety, good taste and significant effect of relieving visual fatigue.

[0010] In order to achieve the above object, the present invention adopts the following technical solutions:

[0011] In a first aspect, the present invention provides a composition for promoting eye health containing lutein ester and zeaxanthin, comprising the following ingredients: lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, arborvitae leaf powder, sweetener, and purified water.

[0012] Preferably, the composition for promoting eye health is a composition for relieving visual fatigue.

[0013] Preferably, the composition for relieving visual fatigue contains the following components by mass per 1000 mL:

[0014] Lutein ester 1.7-1.9g, zeaxanthin 0.52-0.61g, astaxanthin 0.35-0.47g, chrysanthemum extract 30-60g, celery powder 40-70g, Alpinia zeylanicum leaf powder 30-60g, sweetener 110-130g, and the balance is purified water.

[0015] The sweetener is selected from one or more of xylitol, maltitol, erythritol, white sugar, sucrose, brown sugar and honey.

[0016] Most preferably, the composition for relieving visual fatigue contains the following components by mass per 1000 mL:

[0017] Lutein ester 1.8g, zeaxanthin 0.55g, astaxanthin 0.40g, chrysanthemum extract 55g, celery powder 60g, Alpinia zeylanicum leaf powder 55g, sweetener 125g, and the balance is purified water.

[0018] The sweetener is selected from one or more of xylitol, white sugar and honey.

[0019] In a second aspect, the present invention provides a method for preparing the composition for promoting eye health according to the first aspect, the specific steps are as follows:

[0020] S1. Weigh lutein esters, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, zingiber officinale leaf powder, and sweetener, and conduct preliminary food safety inspection;

[0021] S2. Add the sweetener into purified water to dissolve, then add the chrysanthemum extract, celery powder, and Alpinia officinalis leaf powder, heat to 60-75° C., and stir evenly to obtain liquid A;

[0022] S3, cooling liquid A to 25-35°C, adding zeaxanthin, astaxanthin and lutein ester, stirring evenly, filtering, and obtaining liquid B;

[0023] S4. Fill, sterilize, box, and store liquid B.

[0024] The S3 filtration step is to filter using a 50-100 micron filter.

[0025] The S4 sterilization is sterilized by pasteurization or ultra-high temperature instantaneous sterilization.

[0026] The S4 is stored in a warehouse at room temperature and away from light.

[0027] Preferably, the method for preparing the composition for promoting eye health is a method for preparing a composition for relieving visual fatigue, and the specific steps are as follows:

[0028] S1. Weigh lutein esters, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, zingiber officinale leaf powder, and sweetener, and conduct preliminary food safety inspection;

[0029] S2. Add the sweetener into purified water to dissolve, then add the chrysanthemum extract, celery powder, and Alpinia officinalis leaf powder, heat to 60-75° C., and stir evenly to obtain liquid A;

[0030] S3, cooling liquid A to 25-35°C, adding zeaxanthin, astaxanthin and lutein ester, stirring evenly, filtering, and obtaining liquid B;

[0031] S4. Fill, sterilize, box, and store liquid B.

[0032] The S3 filtration step is to filter using a 50-100 micron filter.

[0033] The S4 sterilization is sterilized by pasteurization or ultra-high temperature instantaneous sterilization.

[0034] The S4 is stored in a warehouse at room temperature and away from light.

[0035] Compared with the prior art, the present invention has the following beneficial effects: the present invention provides a composition for promoting eye health containing lutein ester and zeaxanthin, wherein the effect of promoting eye health is specifically to relieve visual fatigue, and the composition with the effect of relieving visual fatigue is compounded by lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, elizabeth leaf powder, sweetener and purified water, wherein the soluble fiber in the chrysanthemum extract is fermented by beneficial bacteria in the intestine to produce short-chain fatty acids, and the intestinal wall cells can promote the absorption of nutrients by the intestinal wall cells through G protein coupled receptors such as GPR43 and GPR41 under the stimulation of short-chain fatty acids, and the short-chain fatty acids can also be intestinal The invention provides energy to cells, improves the activity of intestinal cells, enhances the metabolic activity of intestinal cells, and promotes the absorption of nutrients by intestinal cells; the water-insoluble dietary fiber in celery powder and elizabeth elizabeth powder can promote intestinal peristalsis and enhance intestinal vitality, and the quercetin, luteolin, acacia, apigenin, dihydrochalcone and vitamin C rich in chrysanthemum extract, celery powder and elizabeth elizabeth powder can help protect intestinal cells from damage by oxidative stress and further maintain the health of intestinal cells; astaxanthin has a certain algae smell, and the common use of astaxanthin with chrysanthemum extract, celery powder and elizabeth elizabeth powder can effectively mask its algae smell, making it easier for users to accept the composition. DETAILED DESCRIPTION

[0036] In order to better understand the present invention, the present invention is further described below in conjunction with specific examples, wherein the terms used in the examples are for describing specific embodiments and do not constitute limitations on the scope of protection of the present invention.

[0037] The experimental methods in the following examples without specifying specific conditions are usually carried out under conventional conditions or under conditions recommended by the manufacturer. Unless otherwise specified, percentages and parts are calculated by weight.

[0038] Some raw materials and their sources are as follows:

[0039] Lutein esters: purchased from Guangdong Mingcheng Biotechnology Co., Ltd.;

[0040] Zeaxanthin: purchased from Guangzhou Huayu Biotechnology Co., Ltd.;

[0041] Astaxanthin: purchased from Guangzhou Huayu Biotechnology Co., Ltd.;

[0042] Chrysanthemum extract: purchased from Guangzhou Huayu Biotechnology Co., Ltd.;

[0043] Celery powder: purchased from Guangzhou Huayu Biotechnology Co., Ltd.;

[0044] Ligusticum chuanxiong leaf powder: purchased from Shaanxi Snotech Biotechnology Co., Ltd.;

[0045] Oatmeal flour, kale flour, barley leaf flour, soybean flour, pectin powder, bamboo shoot powder, and coix seed powder were purchased from Guangzhou Huayu Biotechnology Co., Ltd.

[0046] Xylitol: purchased from Jiangsu Hengxingyuan Food Additive Co., Ltd.

[0047] White sugar: purchased from Angel E-Commerce (Yichang) Co., Ltd.;

[0048] Honey: purchased from Henan Dabieshan Zhan's Bee Farm Co., Ltd.

[0049] The mass ratio of each component of the composition for relieving visual fatigue per 1000 mL is shown in Table 1:

[0050] Table 1 Mass ratio of each component per 1000 mL of the composition for relieving visual fatigue

[0051]

[0052]

[0053] The above-mentioned compositions 1-5 for relieving visual fatigue and compositions for relieving visual fatigue The preparation method is as follows:

[0054] S1. Weigh lutein esters, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, zingiber officinale leaf powder, and sweetener, and conduct preliminary food safety inspection;

[0055] S2. Add the sweetener into purified water to dissolve, then add the chrysanthemum extract, celery powder, and Alpinia officinalis leaf powder, heat to 65° C., and stir evenly to obtain liquid A;

[0056] S3, cooling liquid A to 30°C, adding zeaxanthin, astaxanthin and lutein ester, stirring evenly, and filtering through a 100 micron bag filter to obtain liquid B;

[0057] S4. Fill liquid B, sterilize it using ultra-high temperature instantaneous sterilization, pack it into boxes, store it at room temperature, and keep it away from light.

[0058] Composition 6 for relieving visual fatigue:

[0059] The formula used in the composition 6 for relieving visual fatigue is the same as that in the composition 1 for relieving visual fatigue, but the difference from the composition 1 for relieving visual fatigue is that the preparation method thereof is as follows:

[0060] S1. Weigh lutein esters, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, zingiber officinale leaf powder, and sweetener, and conduct preliminary food safety inspection;

[0061] S2. Add the sweetener into purified water to dissolve, then add the chrysanthemum extract, celery powder, and Alpinia officinalis leaf powder, heat to 60° C., and stir evenly to obtain liquid A;

[0062] S3, cooling liquid A to 35°C, adding zeaxanthin, astaxanthin and lutein ester, stirring evenly, and filtering through a 50 micron bag filter to obtain liquid B;

[0063] S4. Fill liquid B, sterilize it by pasteurization, pack it into boxes, store it at room temperature, and keep it away from light.

[0064] Composition 7 for relieving visual fatigue:

[0065] The formula used in the visual fatigue relieving composition 7 is the same as that in the visual fatigue relieving composition 1, but the difference from the visual fatigue relieving composition 1 is that the preparation method thereof is as follows:

[0066] S1. Weigh lutein esters, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, zingiber officinale leaf powder, and sweetener, and conduct preliminary food safety inspection;

[0067] S2. Add the sweetener into purified water to dissolve, then add the chrysanthemum extract, celery powder, and Alpinia officinalis leaf powder, heat to 75° C., and stir evenly to obtain liquid A;

[0068] S3, cooling liquid A to 25° C., adding zeaxanthin, astaxanthin, and lutein ester, stirring evenly, and filtering with a 70 μm bag filter to obtain liquid B;

[0069] S4. Fill liquid B, sterilize it by ultra-high temperature instantaneous sterilization, pack it into boxes, store it at room temperature, and keep it away from light.

[0070] Composition for relieving visual fatigue

[0071] Composition for relieving visual fatigue The formula used is the same as the visual fatigue relieving composition 1, and the difference from the visual fatigue relieving composition 1 is that the preparation method thereof is as follows:

[0072] S1. Weigh lutein esters, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, zingiber officinale leaf powder, and sweetener, and conduct preliminary food safety inspection;

[0073] S2, adding the sweetener to pure water to dissolve, then adding chrysanthemum extract, celery powder, zingiber officinale leaf powder, zeaxanthin, astaxanthin, and lutein ester, heating to 65° C., stirring evenly, and filtering with a 100 μm bag filter to obtain liquid A;

[0074] S3. Fill liquid A, sterilize it by ultra-high temperature instantaneous sterilization, pack it into boxes, store it at room temperature, and keep it away from light.

[0075] Test 1: Persistence of Vision

[0076] The determination of visual persistence was carried out in accordance with the "Evaluation Method for Relieving Visual Fatigue Function" in the "Notice on Issuing the Evaluation Method for Antioxidant Function and 9 Health Function Evaluation Methods (2012) No. 107)". The visual persistence of the experimental group before and after the comparison was significant (p<0.05), and the average visual persistence was improved by 10% or more, which was effective. The results of visual persistence are shown in Table 2.

[0077] Table 2 Results of visual persistence

[0078]

[0079] Note:" ※ ” represents p<0.05.

[0080] It can be seen from Table 2 that after using the compositions 1-5 provided by the invention, compared with before the test, the improvement of the visual persistence was greater than 10%, which proves that the composition provided by the invention has the function of improving visual fatigue. In addition, from the results of composition 1 and compositions ①-④, it can be seen that the efficacy obtained by the present invention is not due to simple superposition, among which lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, and Alpinia officinalis leaf powder have a synergistic effect.

[0081] The composition Compared with the results of composition 1, it can be seen that replacing the chrysanthemum extract, celery powder, and zingiber officinale powder in the present invention with equal amounts of common dietary fiber cannot achieve the same effect. This may be because the apigenin and flavonoids in the celery powder in the composition of the present invention and the polysaccharide compounds in the chrysanthemum extract and the mucus protein and natural pectin in the zingiber officinale powder have a certain synergistic effect, which can promote the absorption of natural active substances by intestinal wall cells.

[0082] Composition Although the formula is the same as composition 1, the preparation method is different, resulting in a significant difference in the effect. The difference may be due to the high temperature, which causes zeaxanthin, astaxanthin, and lutein esters to be oxidized and lose their activity.

[0083] Test 2: Sensory evaluation test

[0084] Select 4 ℃, 25 ℃ and 35 ℃ environment temperature to test composition 1, 6, 7 and composition The sensory scores were measured every five days for a total of 30 days.

[0085] Ten personnel who had received sensory evaluation training were selected to conduct a comprehensive evaluation and scoring of the products according to the scoring criteria in Table 3. The final evaluation results were averaged. The sensory evaluation scoring criteria are shown in Table 3, and the final average scores are shown in Table 4.

[0086] Table 3 Sensory evaluation scoring criteria

[0087]

[0088]

[0089] Table 4 Mean sensory evaluation scores

[0090]

[0091] According to the above scoring criteria, after evaluation by professional technicians, the scores of compositions 1, 6, and 7 were all above 90 points, while compositions ①- In the sensory evaluation, algae smell was found, and the algae smell was the strongest in composition ④. Composition ⑥ had a bitter taste, composition ⑦ had a grassy taste, and composition ⑧ had a sticky feeling. In addition, composition Obvious precipitation occurs, which may be due to the fact that the temperature is too high when the raw materials are added, causing some of the raw materials to precipitate after cooling, resulting in obvious coagulation.

[0092] The embodiments described above are part of the embodiments of the present application, rather than all of the embodiments. The detailed description of the embodiments of the present application is not intended to limit the scope of the present application for protection, but merely represents the selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without making creative work are within the scope of protection of the present application.

Claims

1. A composition for promoting eye health containing lutein esters and zeaxanthin, characterized in that: Each 1000 mL of the composition contains the following ingredients by mass: 1.7-1.9 g of lutein ester, 0.52-0.61 g of zeaxanthin, 0.35-0.47 g of astaxanthin, 30-60 g of chrysanthemum extract, 40-70 g of celery powder, 30-60 g of Alpinia zeylanicum leaf powder, 110-130 g of sweetener, and the balance is purified water.

2. The composition for promoting eye health according to claim 1, characterized in that: Each 1000 mL of the composition contains the following ingredients by mass: 1.8 g of lutein ester, 0.55 g of zeaxanthin, 0.40 g of astaxanthin, 55 g of chrysanthemum extract, 60 g of celery powder, 55 g of Alpinia zeylanicum leaf powder, 125 g of sweetener, and the balance is purified water.

3. The composition for promoting eye health according to claim 1 or 2, characterized in that: The sweetener is selected from one or more of xylitol, maltitol, erythritol, white sugar, sucrose, brown sugar and honey.

4. A method for preparing a composition for promoting eye health as claimed in any one of claims 1 to 3, characterized in that: The specific steps include: S1. Weigh lutein esters, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, zingiber officinale leaf powder, and sweetener, and conduct preliminary food safety inspection; S2. Add the sweetener into purified water to dissolve, then add the chrysanthemum extract, celery powder, and Alpinia officinalis leaf powder, heat to 60-75° C., and stir evenly to obtain liquid A; S3, cooling liquid A to 25-35°C, adding zeaxanthin, astaxanthin and lutein ester, stirring evenly, filtering, and obtaining liquid B; S4. Fill, sterilize, box, and store liquid B.

5. The preparation method according to claim 4, characterized in that: The filtration in step S3 is performed using a 50-100 micron filter.

6. The preparation method according to claim 4, characterized in that: The sterilization in step S4 is performed by pasteurization or ultra-high temperature instantaneous sterilization.

7. The preparation method according to claim 4, characterized in that: The storage conditions in step S4 are room temperature and light-proof.

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