Plateau environment simulation device for animal experiment
By designing a device including a transparent animal compartment, an environmental adjustment device, a temporary compartment, an animal compartment and a lifting device, the problem of difficulty in maintaining the animal compartment environment in animal experiments is solved, and the effect of maintaining the plateau environment during feeding and cleaning is achieved.
Patent Information
- Application Number
- CN202411742665.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-29
- Publication Date
- 2025-03-14
AI Technical Summary
In animal experiments, it is difficult to maintain the plateau environment in the animal compartment when animals are fed and excreted, which affects the sustainability of the experiment.
A device including a transparent animal compartment, an environmental regulation device, a temporary compartment, an animal compartment and a lifting device is designed to isolate the animal compartment when connected to the outside world through a temporary compartment, maintain the plateau environment, and realize the addition of food and water and the cleaning of excrement through the lifting device and opening and closing structure.
During the animal feeding and excretion cleaning process, the plateau environment in the animal cabin is maintained, environmental mutations are avoided, and the sustainability of animal experiments and the accuracy of experimental results are ensured.
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Figure CN119605671A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the field of experimental equipment, and in particular to a plateau environment simulation device for animal experiments. Background Art
[0002] There are many differences between the environment in plateau areas and low-altitude areas, including thin air, low air pressure, and low oxygen content in the air. People from low-altitude areas may experience altitude sickness such as nausea, vomiting, palpitations, and dizziness due to the different environment. They may even develop altitude sickness due to the inability to adapt to the low-oxygen environment of the plateau. Altitude sickness includes high-altitude pulmonary edema, high-altitude cerebral edema, and high-altitude polycythemia.
[0003] Using animal experiments to study the pathogenesis of some diseases and their prevention and treatment plans is a common research method in the medical field. Therefore, a plateau environment simulation device for animal experiments has emerged. Common plateau environment simulation devices for animal experiments have a closed animal cabin, and are provided with a device for controlling the air conditions and light conditions in the animal cabin to make the environment in the animal cabin consistent with that in the plateau area. When the animal is placed in the animal cabin, the animal is equivalent to being in the plateau area, so that it is very convenient to simulate the animal from a low altitude area to a plateau area, so as to conduct relevant animal research. Patents with application numbers 201510283490.5, 201921902600.1, and 200620085678.5 disclose such a plateau environment simulation device for animal experiments.
[0004] In the above-mentioned animal experiments, animals need to survive in the animal cabin for a long time. During this process, the animals need to be fed, their excrement needs to be cleaned, and the animal cabin needs to be opened. At this time, outside air enters the cabin, and the cabin can no longer maintain the plateau environment, which has a significant impact on the sustainability of the experiment. Summary of the invention
[0005] The technical problem to be solved by the present invention is to provide a plateau environment simulation device for animal experiments, which allows the animals to remain in a plateau environment during feeding and excrement cleaning.
[0006] The technical solution adopted to solve the above technical problems is: the plateau environment simulation device for animal experiments includes an animal cabin and an environment adjustment device, the animal cabin is light-permeable, and the environment adjustment device acts on the animal cabin; it also includes a device frame, a temporary cabin, an animal frame, a lifting device, an opening and closing structure and a first pressing structure;
[0007] The device frame includes a base, a horizontal pad and a horizontal cover plate which are arranged in sequence from bottom to top, the horizontal pad plate has a pad hole, the horizontal cover plate has a first cover plate air hole, a second cover plate air hole and a temporary hatch hole which are arranged at intervals, and the temporary hatch hole is located between the first cover plate air hole and the second cover plate air hole;
[0008] There are two animal cabins, which include a main cabin body and a main cabin cover. The main cabin cover is covered on the main cabin body, and is provided with a first cabin cover air hole, a second cabin cover air hole and a connecting hole. One animal cabin is arranged between a horizontal pad and a horizontal cover plate. A first clamping structure passes through the pad hole and presses on the animal cabin to make the main cabin cover and the horizontal cover plate close to each other. The first cabin cover air hole, the second cabin cover air hole and the connecting hole are respectively opposite to the first cover plate air hole, the second cover plate air hole and the temporary cabin hole. The clamping of the first clamping structure can be released and its clamping end can be moved to be located under the horizontal pad plate. The other animal cabin is reserved.
[0009] The volume of the temporary cabin is smaller than that of the animal cabin. The temporary cabin includes a temporary cabin cover and a temporary cabin lid. The temporary cabin cover is connected to the horizontal cover plate and corresponds to the temporary cabin hole. The temporary cabin cover has an operation hole, and the temporary cabin lid closes the operation hole.
[0010] The animal frame is located in the animal cabin and directly below the temporary cabin, and water and food items are provided in the animal frame; the lifting device is connected to the animal frame, and the lifting device can drive the animal frame to move up and down so that the animal frame can be located in the temporary cabin; the opening and closing structure is arranged corresponding to the bottom of the temporary cabin, and the opening and closing structure can control whether the temporary cabin is connected to the animal cabin;
[0011] The environment adjustment device comprises an air intake device and an exhaust device, wherein the air intake device and the exhaust device are both connected to the horizontal cover plate and correspond to the air holes of the first cover plate and the air holes of the second cover plate respectively.
[0012] Furthermore, the horizontal pad is provided with a guide structure for guiding the animal cabin to be placed at a specified position.
[0013] Furthermore, the animal cabin comprises an inner partition, a padding strip having a distance from the bottom surface of the main cabin body is provided in the main cabin body, the inner partition is placed on the padding strip, and a plurality of drainage holes are provided on the inner partition.
[0014] Furthermore, the first clamping structure includes a swing clamping frame and a first telescopic cylinder. The swing clamping frame is hinged to the device frame so that it can swing up and down. The two ends of the first telescopic cylinder are respectively hinged to the device frame and the swing clamping frame. The first telescopic cylinder can drive the swing clamping frame to swing.
[0015] Furthermore: the temporary cabin cover is provided with an annular pad corresponding to the temporary cabin hole and arranged horizontally; the opening and closing structure includes a second telescopic cylinder, a closed cover plate and a second clamping structure, the second telescopic cylinder is fixedly arranged and connected to the closed cover plate, the second telescopic cylinder can drive the closed cover plate to move horizontally so that the closed cover plate is covered on the annular pad or removed, and the second clamping structure is used to clamp the closed cover plate when the closed cover plate is covered on the annular pad.
[0016] Furthermore, the second clamping structure includes a clamping plate and a third telescopic cylinder, the third telescopic cylinder is vertically fixed, and the clamping plate is connected to the lower end of the third telescopic cylinder.
[0017] Furthermore, the animal frame comprises a frame body, a frame cover and a frame cover driver. An animal inlet and outlet are arranged on the side of the frame body. The frame cover covers the animal inlet and outlet. The frame cover driver can drive the frame cover to switch.
[0018] Furthermore, the upper end of the frame cover is hinged to the frame body, and a connecting rod extending to the upper part of the frame body is arranged on the upper end of the frame cover. The frame cover driver is a fourth telescopic cylinder, and both ends of the fourth telescopic cylinder are respectively hinged to the connecting rod and the frame body.
[0019] Furthermore, the animal frame comprises a frame upper cover, the upper end of the frame is provided with a frame upper opening, and the frame upper opening corresponds to the position of the operation hole.
[0020] Furthermore, the lifting device is a fifth telescopic cylinder.
[0021] The beneficial effects of the present invention are as follows: Figure 1 As shown in the prior art, the animals are placed in the animal cabin, and the environment regulating device makes the air condition in the animal cabin consistent with that in the plateau area. The opening and closing structure is opened, and the lifting device makes the animal frame located at the bottom of the animal cabin. A water feeding device is provided in the animal frame, and the animals can enter the animal frame to eat and drink. Since the opening and closing structure is opened, the environment in the temporary cabin is consistent with that in the animal cabin.
[0022] When food and water are needed, Fig.11 As shown, when all animals leave the animal frame, the lifting device moves the animal frame up to the temporary cabin, and the opening and closing structure is closed. At this time, the temporary cabin is separated from the animal cabin. Open the temporary cabin cover, add food and water to the animal frame, and the temporary cabin is connected to the outside world, so the air inside becomes normal pressure; since the temporary cabin is separated from the animal cabin, it does not affect the environment inside the animal cabin. Then close the temporary cabin cover to re-close the temporary cabin. Then the lifting device moves the animal frame down to the animal cabin, and the device returns to Figure 1 The normal use state shown in the figure, at this time, the normal pressure air in the temporary cabin is mixed with the air in the animal cabin; because the temporary cabin is small in size and the air that can be mixed into the animal cabin is only the air in the temporary cabin, the impact on the environment in the animal cabin is very small. Therefore, during the whole process of adding food and water, the environment of the animals remains basically unchanged, maintaining the plateau environment.
[0023] When you need to clean up the animal excrement, add food and water to the animal frame, introduce the animal into the animal frame, and then adjust the device to the following conditions: Fig.11 The animal frame is located in the temporary cabin, and the opening and closing structure is closed. At this time, the temporary cabin still maintains the plateau environment, and the animal is temporarily located in the temporary cabin. Then the first pressing structure is released. Then the animal cabin is moved out, and a clean animal cabin is replaced, and the animal cabin is pressed with the first pressing structure. Then the environment adjustment device is turned on, and the environment in the animal cabin is quickly adjusted to the plateau environment. Then the opening and closing structure is opened, and the lifting device moves the animal frame down to the animal cabin, and the device returns to Figure 1 The normal use status shown. During the whole process, the animals are in the plateau environment; the animal cabins are replaced to quickly get clean animal cabins, and the replaced animal cabins are cleaned and put into use. The animals are in the closed temporary cabins for a very short time, which has no adverse effects on the animals.
[0024] In summary, in the process of adding animal food and water, and cleaning the animal cabin, the animals are kept in a plateau environment, avoiding sudden changes in the environment in which the animals are located, ensuring that the animal experiment continues for a long time, and facilitating obtaining more accurate experimental results. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] Figure 1 This is a structural diagram of a plateau environment simulation device for animal experiments;
[0026] Figure 2 It is the structural diagram of the device frame;
[0027] Figure 3 It is the structural diagram of the horizontal pad;
[0028] Figure 4 It is the structural diagram of the horizontal cover;
[0029] Figure 5 It is the structural diagram of the animal compartment;
[0030] Figure 6 is a structural diagram of the first compression structure;
[0031] Figure 7 It is a structural diagram of the temporary cabin, animal frame and opening and closing structure;
[0032] Figure 8 It is the main view of the animal frame;
[0033] Fig. 9 It is the left view of the animal frame;
[0034] Fig.10 The second clamping structure
[0035] Fig.11 It is a state diagram of the animal frame being located in the temporary cabin;
[0036] The markings in the figure are: device frame 1, base 11, horizontal pad 12, guide structure 121, pad hole 121, horizontal cover plate 13, first cover plate air hole 131, temporary cabin hole 132, second cover plate air hole 133, first clamping structure 2, swing clamping frame 21, first telescopic cylinder 22, animal cabin 3, main cabin body 31, pad 311, main cabin cover 32, first cabin cover air hole 321, connecting hole 322, second cabin cover air hole 323, inner partition 33 , temporary cabin 4, temporary cabin cover 41, operating hole 411, annular pad 412, temporary cabin cover 42, animal frame 5, frame body 51, frame body upper cover 52, frame cover 53, fourth telescopic cylinder 54, connecting rod 531, opening and closing structure 6, second telescopic cylinder 61, closing cover plate 62, second clamping structure 63, clamping plate 631, third telescopic cylinder 631, fifth telescopic cylinder 7, environmental adjustment device 8, air intake device 81, exhaust device 82, lighting device 83. DETAILED DESCRIPTION
[0037] The present invention is further described below in conjunction with the accompanying drawings and specific embodiments.
[0038] like Figures 1 to 10As shown, the plateau environment simulation device for animal experiments includes an animal cabin 3 and an environment adjustment device 8, the animal cabin 3 is light-permeable, and the environment adjustment device 8 acts on the animal cabin 3; it also includes a device frame 1, a temporary cabin 4, an animal frame 5, a lifting device, an opening and closing structure 6 and a first pressing structure 2; the device frame 1 includes a base 11, a horizontal pad 12 and a horizontal cover plate 13 arranged in sequence from bottom to top, the horizontal pad 12 has a pad hole 121, the horizontal cover plate 13 has a first cover plate air hole 131, a second cover plate air hole 133 and a temporary cabin hole 132 arranged at intervals, and the temporary cabin The hole 132 is located between the first cover plate air hole 131 and the second cover plate air hole 133; there are two animal cabins 3, and the animal cabin 3 includes a main cabin body 31 and a main cabin cover 32, the main cabin cover 32 is covered on the main cabin body 31, and the main cabin cover 32 has a first cabin cover air hole 321, a second cabin cover air hole 323 and a connecting hole 322; one animal cabin 3 is arranged between the horizontal pad 12 and the horizontal cover 13, the first pressing structure 2 passes through the pad hole 121 and pushes up the animal cabin 3 to make the main cabin cover 32 and the horizontal cover 13 close to each other, the first cabin cover air hole 321, the second cabin cover air hole 323 and the connecting hole 322 23 and the connecting hole 322 are respectively opposite to the first cover plate air hole 131, the second cover plate air hole 133 and the temporary cabin hole 132; the compression of the first clamping structure 2 can be released and its clamping end can be moved to be located below the horizontal pad 12; another animal cabin 3 is reserved; the volume of the temporary cabin is smaller than that of the animal cabin 3, the temporary cabin 4 includes a temporary cabin cover 41 and a temporary cabin cover 42, the temporary cabin cover 41 is connected to the horizontal cover 13 and corresponds to the temporary cabin hole 132, the temporary cabin cover 41 has an operating hole 411, and the temporary cabin cover 42 closes the operating hole 411; the animal frame 5 is located at the animal The animal frame 5 is provided with water and food items in the cabin 3 and is located directly below the temporary cabin 4; the lifting device is connected to the animal frame 5, and the lifting device can drive the animal frame 5 to move up and down so that the animal frame 5 can be located in the temporary cabin 4; the opening and closing structure 6 is arranged corresponding to the bottom of the temporary cabin 4, and the opening and closing structure 6 can control whether the temporary cabin 4 is connected to the animal cabin 3; the environmental adjustment device 8 includes an air intake device 81 and an exhaust device 82, and the air intake device 81 and the exhaust device 82 are both connected to the horizontal cover plate 13 and correspond to the first cover plate air holes 131 and the second cover plate air holes 133 respectively.
[0039] The conventional use state of the present invention is as follows Figure 1 As shown in the prior art, the animal is located in the animal cabin 3, and the environment adjustment device 8 makes the air condition in the animal cabin 3 consistent with that in the plateau area. The opening and closing structure 6 is opened, and the lifting device 7 makes the animal frame 5 located at the bottom of the animal cabin 3. A water feeding device is set in the animal frame 5, and the animal can enter the animal frame 5 to eat and drink. Since the opening and closing structure 6 is opened, the environment in the temporary cabin 4 is consistent with that in the animal cabin 3.
[0040] When food and water are needed, Fig.11As shown, when all animals leave the animal frame 5, the lifting device 7 moves the animal frame 5 up to the temporary cabin 4, and the opening and closing structure 6 is closed. At this time, the temporary cabin 4 is separated from the animal cabin 3. Open the temporary cabin cover 42, add food and water to the animal frame 5, and the temporary cabin 4 is connected to the outside world, so the internal air becomes normal pressure; since the temporary cabin 4 is separated from the animal cabin 3, it does not affect the environment in the animal cabin 3. Then close the temporary cabin cover 43 to re-close the temporary cabin 4. Then the lifting device 7 moves the animal frame 5 down to the animal cabin 3, and the device returns to the state of being closed. Figure 1 In the normal use state shown, the normal pressure air in the temporary cabin 4 is mixed with the air in the animal cabin 3; because the temporary cabin 4 is small in size and the air that can be mixed into the animal cabin 3 is only the air in the temporary cabin 4, the impact on the environment in the animal cabin 3 is very small. Therefore, during the whole process of adding food and water, the environment of the animals remains basically unchanged, and the plateau environment is maintained.
[0041] When it is necessary to clean the animal excrement, add food and water to the animal frame 5, introduce the animal into the animal frame 5, and then adjust the device to the following conditions: Fig.11 The animal frame 5 shown is located in the temporary cabin 4, and the opening and closing structure 6 is closed. At this time, the temporary cabin 4 still maintains the plateau environment, and the animal is temporarily located in the temporary cabin 4. Then the first pressing structure 2 is released. Then the animal cabin 3 is moved out, and a clean animal cabin 3 is replaced, and the animal cabin 3 is pressed with the first pressing structure 2. Then the environment adjustment device 8 is turned on, and the environment in the animal cabin 3 is quickly adjusted to the plateau environment. Then the opening and closing structure 6 is opened, and the lifting device 7 moves the animal frame 5 down to the animal cabin 3, and the device returns to the original state. Figure 1 The normal use state shown. During the whole process, the animals are in the plateau environment; the animal cabin 3 can be replaced to quickly obtain a clean animal cabin 3, and the replaced animal cabin 3 is cleaned and put into use, and the time that the animals are in the closed temporary cabin 4 is very short, which has no adverse effects on the animals.
[0042] In summary, in the process of adding animal food and water, and cleaning the animal cabin 3, the animals are kept in a plateau environment, avoiding sudden changes in the environment in which the animals are located, ensuring that the animal experiment continues for a long time, and facilitating obtaining more accurate experimental results.
[0043] The environment regulating device 8 can be designed with reference to the prior art, for example, with reference to the patents with application numbers 201510283490.5, 201921902600.1, and 200620085678.5 described in the background art. The air intake device 81 fills the air with adjusted temperature and humidity into the animal cabin 3, and the exhaust device 82 controls the discharge of gas in the animal cabin 3 so that the air pressure in the animal cabin 3 is lower than the external environment. The environment regulating device 8 may also include a lighting device 83, which is set with reference to the prior art and is used to simulate plateau lighting. The temporary cabin 4 and the horizontal cover plate 13 should be light-transmissive, for example, transparent, so that the light emitted by the lighting device 83 can shine in. The present invention has multiple opening sealing places. In order to ensure the sealing effect, sealing structures such as sealing pads can be set at these places.
[0044] The specific process of removing the animal cabin 3 is: the first clamping structure 2 is released from the clamping, the animal cabin 3 is moved down to be placed on the horizontal pad 12, and then it is pulled out from the horizontal pad 12 and removed from the device frame 1. The specific process of removing the clean spare animal cabin 3 is: one end of the animal cabin 3 is placed on the horizontal pad 12, and then pushed inward to the specified position, that is, the first hatch cover air hole 321, the second hatch cover air hole 323 and the connecting hole 322 are respectively opposite to the first cover plate air hole 131, the second cover plate air hole 133 and the temporary cabin hole 132; then the first clamping structure 2 is pushed up and clamps the animal cabin 3. In order to enable the animal cabin 3 to be quickly moved to the specified position when it is installed, it is preferred that the horizontal pad 12 has a guide structure 121 for guiding the animal cabin 3 to be placed in the specified position. The guide structure 121 can be specifically as follows Figure 3 As shown, the shape is U-shaped, and the three sides of the animal cabin 3 are in contact with the three sides of the guide structure 121, and the animal cabin 3 is located at the specified position. In this way, the installation speed of the animal cabin 3 can be further improved.
[0045] The specific structure of the animal cabin 3 is as follows: the animal cabin 3 includes an inner partition 33, a pad 311 with a distance from the bottom surface of the main cabin 31 is provided in the main cabin body 31, the inner partition 33 is placed on the pad 311, and the inner partition 33 has a plurality of holes for draining. The urine and part of the feces of the animal can drain from the holes, which is conducive to ensuring that the inner partition 33 is dry. The animal moves on the inner partition 33. After the animal cabin 3 is disassembled, the main cabin cover 32 is opened, and the inner partition 33 is removed, and it can be thoroughly cleaned. The animal cabin 3 can be made of plastic, which is lighter and more convenient to replace.
[0046] The specific structure of the first pressing structure 2 can be as follows Figure 6 As shown, the first clamping structure 2 includes a swing clamping frame 21 and a first telescopic cylinder 22. The swing clamping frame 21 is hinged to the device frame 1 so as to be able to swing up and down. The two ends of the first telescopic cylinder 22 are respectively hinged to the device frame 1 and the swing clamping frame 21. The first telescopic cylinder 22 can drive the swing clamping frame 2 to swing. The first telescopic cylinder 22 drives the clamping frame 2 to swing upwards, that is, to clamp, and to swing downwards, that is, to release.
[0047] The specific structure of the opening and closing structure 6 is as follows Figure 7 As shown, the temporary cabin cover 41 is provided with an annular pad 412 corresponding to the temporary cabin hole 132 and arranged horizontally; the opening and closing structure 6 includes a second telescopic cylinder 61, a closed cover plate 62 and a second clamping structure 63, the second telescopic cylinder 61 is fixedly arranged and connected to the closed cover plate 62, the second telescopic cylinder 61 can drive the closed cover plate 62 to move horizontally so that the closed cover plate 62 covers the annular pad 412 or moves away, and the second clamping structure 63 is used to clamp the closed cover plate 62 when the closed cover plate 62 covers the annular pad 412.
[0048] The second telescopic cylinder 61 telescopes and drives the closed cover plate 62 to move, that is, controls the opening and closing of the inner hole of the annular pad 412, and also controls whether the temporary cabin 4 is connected with the animal cabin 3. However, the closed cover plate 62 alone covering the annular pad 412 cannot ensure sealing, so the second pressing structure 63 is required to press the closed cover plate 62 to ensure sealing between the cover plate 62 and the annular pad 412.
[0049] The specific structure of the second clamping structure 63 is as follows: the second clamping structure 63 includes a clamping plate 631 and a third telescopic cylinder 631, the third telescopic cylinder 631 is vertically fixed, and the clamping plate 631 is connected to the lower end of the third telescopic cylinder 631. The third telescopic cylinder 631 can be extended to allow the clamping plate 631 to clamp or loosen the cover plate 62.
[0050] The specific structure of the animal frame 5 can be as follows Figure 8 and Fig. 9 As shown, the animal frame 5 includes a frame body 51, a frame cover 53 and a frame cover driver. An animal inlet and outlet are arranged on the side of the frame body 51. The frame cover 53 covers the animal inlet and outlet. The frame cover driver can drive the frame cover 53 to open and close.
[0051] The frame cover 53 and the frame cover driver are used to control the opening or closing of the animal frame 5. When the animal frame 5 is located in the animal cabin 3, the frame cover 53 should generally be opened to facilitate the entry and exit of the animal. When the animal frame 5 is to be moved to the temporary cabin 4, the lower frame cover 53 should be closed. When the animal frame 5 is to be moved to the temporary cabin 4 with the animal, food and water can be placed in the animal frame 5 to lure the animal in and then close the frame cover 53.
[0052] Specifically, the upper end of the frame cover 53 is hinged to the frame body 51, and a connecting rod 531 extending to the upper side of the frame body 51 is provided at the upper end of the frame cover 53. The frame cover driver is a fourth telescopic cylinder 54, and the two ends of the fourth telescopic cylinder 54 are respectively hinged to the connecting rod 531 and the frame body 51. The animal frame 5 includes a frame upper cover 52, and the upper end of the frame body 51 has a frame upper opening, and the frame upper opening corresponds to the position of the operation hole 411.
[0053] The fourth telescopic cylinder 54 can be extended and retracted to drive the frame cover 53 to rotate and open. The opening on the frame corresponds to the position of the operating hole 411. When the opening on the frame is opened, water and food can be added to the animal frame.
[0054] The lifting device is used to drive the animal frame 5 to rise and fall. The specific structure can be as follows: Fig. 9 As shown, the lifting device is the fifth telescopic cylinder 7.
[0055] Each telescopic cylinder of the present invention can be an electric telescopic cylinder. Like common electrical appliances, the present invention needs to be equipped with a conventional electric control device. The electric control device is relatively simple and can control the power on and off of the present invention, control the switch of the environmental adjustment device 8, and control the extension and retraction of each telescopic cylinder. Multiple control buttons can be provided, and the experimenter presses the buttons to perform the above control.
Claims
1. A plateau environment simulation device for animal experiments, comprising an animal cabin (3) and an environment adjustment device (8), wherein the animal cabin (3) is light-transmissive and the environment adjustment device (8) acts on the animal cabin (3); the device is characterized in that: It comprises a device frame (1), a temporary cabin (4), an animal frame (5), a lifting device, an opening and closing structure (6) and a first pressing structure (2); The device frame (1) comprises a base (11), a horizontal pad (12) and a horizontal cover plate (13) which are arranged in sequence from bottom to top, the horizontal pad (12) having a pad hole (121), the horizontal cover plate (13) having a first cover plate air hole (131), a second cover plate air hole (133) and a temporary hatch hole (132) which are arranged at intervals, and the temporary hatch hole (132) is located between the first cover plate air hole (131) and the second cover plate air hole (133); There are two animal cabins (3), each of which comprises a main cabin body (31) and a main cabin cover (32). The main cabin cover (32) covers the main cabin body (31), and the main cabin cover (32) has a first cabin cover air hole (321), a second cabin cover air hole (323) and a connecting hole (322); one animal cabin (3) is arranged between a horizontal pad (12) and a horizontal cover (13), and a first pressing structure (2) passes through the pad hole (121) and The upper animal cabin (3) makes the main cabin cover (32) and the horizontal cover plate (13) close together, and the first cabin cover air hole (321), the second cabin cover air hole (323) and the connecting hole (322) are respectively opposite to the first cover plate air hole (131), the second cover plate air hole (133) and the temporary cabin hole (132); the clamping of the first clamping structure (2) can be released and its clamping end can be moved to be located below the horizontal pad plate (12); another animal cabin (3) is reserved; The volume of the temporary cabin is smaller than that of the animal cabin (3). The temporary cabin (4) comprises a temporary cabin cover (41) and a temporary cabin lid (42). The temporary cabin cover (41) is connected to the horizontal cover plate (13) and corresponds to the temporary cabin hole (132). The temporary cabin cover (41) has an operation hole (411), and the temporary cabin lid (42) closes the operation hole (411). The animal frame (5) is located in the animal cabin (3) and directly below the temporary cabin (4), and water and food items are provided in the animal frame (5); the lifting device is connected to the animal frame (5), and the lifting device can drive the animal frame (5) to move up and down so that the animal frame (5) can be located in the temporary cabin (4); the opening and closing structure (6) is arranged corresponding to the bottom of the temporary cabin (4), and the opening and closing structure (6) can control whether the temporary cabin (4) and the animal cabin (3) are connected; The environment adjustment device (8) comprises an air intake device (81) and an air exhaust device (82), wherein the air intake device (81) and the air exhaust device (82) are both connected to the horizontal cover plate (13) and correspond to the first cover plate air holes (131) and the second cover plate air holes (133), respectively.
2. The plateau environment simulation device for animal experiments according to claim 1, characterized in that: The horizontal pad (12) is provided with a guide structure (121) for guiding the animal cabin (3) to be placed at a specified position.
3. The plateau environment simulation device for animal experiments according to claim 1, characterized in that: The animal cabin (3) comprises an inner partition (33), a padding strip (311) which is spaced from the bottom surface of the main cabin (31) is provided in the main cabin body (31), the inner partition (33) is placed on the padding strip (311), and a plurality of drainage holes are provided on the inner partition (33).
4. The plateau environment simulation device for animal experiments according to claim 1, characterized in that: The first clamping structure (2) comprises a swing clamping frame (21) and a first telescopic cylinder (22); the swing clamping frame (21) is hinged to the device frame (1) so as to be able to swing up and down; the two ends of the first telescopic cylinder (22) are respectively hinged to the device frame (1) and the swing clamping frame (21); the first telescopic cylinder (22) can drive the swing clamping frame (2) to swing.
5. The plateau environment simulation device for animal experiments according to claim 1, characterized in that: The temporary cabin cover (41) is provided with an annular pad (412) corresponding to the temporary cabin hole (132) and arranged horizontally; the opening and closing structure (6) comprises a second telescopic cylinder (61), a closed cover plate (62) and a second pressing structure (63); the second telescopic cylinder (61) is fixedly arranged and connected to the closed cover plate (62); the second telescopic cylinder (61) can drive the closed cover plate (62) to move horizontally so that the closed cover plate (62) covers the annular pad (412) or moves away; the second pressing structure (63) is used to press the closed cover plate (62) when the closed cover plate (62) covers the annular pad (412).
6. The plateau environment simulation device for animal experiments according to claim 5, characterized in that: The second clamping structure (63) comprises a clamping plate (631) and a third telescopic cylinder (631). The third telescopic cylinder (631) is vertically fixed, and the clamping plate (631) is connected to the lower end of the third telescopic cylinder (631).
7. The plateau environment simulation device for animal experiments according to claim 1, characterized in that: The animal frame (5) comprises a frame body (51), a frame cover (53) and a frame cover driver. An animal inlet and outlet are arranged on the side of the frame body (51). The frame cover (53) covers the animal inlet and outlet. The frame cover driver can drive the frame cover (53) to open and close.
8. The plateau environment simulation device for animal experiments according to claim 7, characterized in that: The upper end of the frame cover (53) is hinged to the frame body (51), and a connecting rod (531) extending to the upper side of the frame body (51) is arranged on the upper end of the frame cover (53). The frame cover driver is a fourth telescopic cylinder (54), and the two ends of the fourth telescopic cylinder (54) are respectively hinged to the connecting rod (531) and the frame body (51).
9. The plateau environment simulation device for animal experiments according to claim 8, characterized in that: The animal frame (5) comprises a frame upper cover (52); the upper end of the frame (51) is provided with a frame upper opening, and the position of the frame upper opening corresponds to the operation hole (411).
10. The plateau environment simulation device for animal experiments according to claim 1, characterized in that: The lifting device is a fifth telescopic cylinder (7).
Citation Information
Patent Citations
A low-pressure chamber for experimental animals used for high-altitude medical research and a pressure control method based on the low-pressure chamber
CN104959171B
Plateau human disease model preparation environment simulation system
CN210743373U
Plateau-simulation animal experiment chamber
CN2907570Y
Normal pressure gas experiment animal cabin
CN102973330A
Animal feeding device capable of maintaining steady state of environment in chambers
CN104365494A