Medicinal and edible nutritional composition with effects of benefiting qi and nourishing blood as well as preparation method and application of medicinal and edible nutritional composition

Abstract

The invention provides a medicinal and edible nutritional composition for benefiting qi and nourishing blood and application of the medicinal and edible nutritional composition in preparation of a nutritional preparation for improving deficiency of qi and blood, the composition is prepared from gorse lineata, scrophularia ningpoensis, astragalus membranaceus, polygonatum kingianum, angelica sinensis, fructus lycii, lily, lotus seeds and red dates, and the composition can effectively increase leukocyte count, erythrocyte count and hemoglobin content, enhance physical strength and improve the blood circulation. The nutritional effects of benefiting qi and nourishing blood are achieved.

Description

Technical Field

[0001] The invention relates to the field of medical care, and in particular to a medicinal and edible nutritional composition for replenishing qi and nourishing blood and an application thereof in preparing a nutritional preparation for improving qi and blood deficiency. Background Art

[0002] Traditional Chinese medicine believes that blood is a nutritious red liquid substance that circulates in the blood vessels. It is one of the basic substances that make up the human body and maintain human life activities.

[0003] The functions of blood include:

[0004] (1) Nourishing function. Blood is produced from the essence of food and water, and contains rich nutrients needed by the human body. Blood circulates in the veins, reaching the internal organs and external organs, and continuously nourishing and moisturizing the organs and tissues of the whole body to maintain the physiological functions of the organs and tissues, thus ensuring the normal progress of human life activities. The "Nanjing·Twenty-two Difficulties" summarizes this important function of blood as "blood is responsible for nourishing". The "Suwen·Five Zang Organs Formation" specifically points out: "The liver receives blood and can see, the feet receive blood and can walk, the palms receive blood and can grasp, and the fingers receive blood and can grasp." This shows that the physiological functions of all parts of the body can only be performed normally under the nourishing function of blood. The nourishing function of blood is more obviously reflected in the complexion, muscles, skin, hair, sensation and movement. When the blood volume is sufficient and the nourishing function is normal, the complexion will be ruddy, the muscles will be strong, the skin and hair will be moist, the sensation will be sensitive, and the movement will be free. If the blood volume is insufficient and the nourishing function is weakened, symptoms such as sallow complexion, thin muscles, dry skin, thin hair, numbness of limbs, or motor weakness may occur.

[0005] (2) The role of transforming the spirit. Blood is the main material basis of the body's mental activities. "Suwen·Bazheng Shenming Lun" says: "Blood and qi are the spirit of man, and must be carefully nurtured." "Lingshu·Pingren Juegu" says: "When the blood vessels are harmonious, the spirit can be at home." This shows that the human body's mental activities must be nourished by blood. Only when the material basis is sufficient can there be abundant and comfortable mental and emotional activities. When the human body has abundant blood and qi and the blood vessels are harmonious, the spirit is abundant, the mind is clear, the senses are sensitive, and the thinking is agile. On the contrary, under the influence of many factors, when blood is depleted and blood circulation is abnormal, different degrees of mental and emotional symptoms may occur, such as mental fatigue, forgetfulness, insomnia, dreaminess, irritability, palpitations, and even trance, delirium, coma, etc.

[0006] The formation of blood is inseparable from Qi and its movement and changes. "Lingshu Xieke Pian" says: "Nutrient Qi secretes body fluids, injects them into the veins, and transforms them into blood." When Qi is strong, the function of transforming and generating blood is strong, while when Qi is weak, the function of transforming and generating blood is weak, thus leading to blood deficiency.

[0007] Blood deficiency refers to blood deficiency, which leads to malnutrition of the internal organs, meridians, and body. Common symptoms include pale or sallow complexion, pale lips, tongue, nails, dizziness, palpitations, frequent dreams, numbness of hands and feet, scanty, pale, late or amenorrhea in women, and thin pulse. The etiology and pathogenesis are mostly caused by improper diet, overwork, emotional frustration, excessive blood loss, chronic illness, or physical weakness. In addition to traditional drug treatment, diet therapy is also a common method for the treatment of blood deficiency.

[0008] Aspalathus linearis is a needle-shaped shrub that grows in the Cedarberg Mountains in southern South Africa. It has been used in the local area for hundreds of years. Aspalathus linearis is rich in antioxidants, vitamin C, minerals and proteins. It is often used in South Africa to treat asthma, infant colic, mild depression, irritability and insomnia, anti-allergy, eczema, and relieve skin diseases. It has become a very popular health drink. In 2014, my country approved it as a new food ingredient. Modern pharmacological studies have shown that Aspalathus linearis has antioxidant, hypoglycemic, anti-inflammatory, cardiovascular and cerebrovascular protection, and anti-cancer effects.

[0009] Wang Chandi and others from Beijing University of Chinese Medicine analyzed the literature and believed that the functions and indications of ginseng are to nourish the kidney and replenish essence, invigorate qi and strengthen the spleen, nourish yin and produce body fluid, and calm the mind and soothe the nerves. It is used for low back pain and fatigue, sexual apathy, fatigue, heaviness of limbs, stomach pain, thirst due to loss of body fluid, internal heat and thirst, irritability and insomnia, and forgetfulness. Among them, the effect of invigorating qi and strengthening the spleen comes from the fact that ginseng can lower blood lipids. (Reference: Wang Chandi, Hou Xinjuan, Zhao Fan, et al. Literature research on ginseng and discussion on the medicinal properties of ginseng [J]. Chinese Journal of Traditional Chinese Medicine, 2021, 46(08): 1960-1966.) Since ginseng was approved as a new resource food in 2014, its application has become more and more extensive, but there are few studies on the compatibility of ginseng guided by traditional Chinese medicine theory. Given that ginseng has rich pharmacological effects, conducting prescription compatibility research and developing new products are of practical significance for improving people's health.

[0010] Based on the above theory and the characteristics of the new raw materials, the development of a "medicine and food of the same origin" nutritional composition for replenishing qi and nourishing blood is of great significance for improving nutritional regulation and auxiliary treatment of qi and blood deficiency. Summary of the invention

[0011] The purpose of the present invention is to apply the theory of invigorating qi and nourishing blood in traditional Chinese medicine and the nutritional theory of traditional Chinese medicine and dietary therapy to provide a "medicine and food of the same origin" nutritional product to regulate the nutrition of people with insufficient qi and blood, and maintain the health of weak patients or sub-healthy people.

[0012] The purpose of the present invention is achieved through the following technical methods:

[0013] On the one hand, the present invention provides a nutritious composition of medicine and food for nourishing blood, wherein the composition is prepared from the following raw materials: broom flower, black ginseng, astragalus, polygonatum, angelica, wolfberry, lily, lotus seed, and jujube.

[0014] Preferably, the weight ratio of the raw materials is: 3-20 parts of broom flower, 3-20 parts of black ginseng, 3-20 parts of astragalus, 3-20 parts of polygonatum, 1-10 parts of angelica, 1-10 parts of wolfberry, 1-10 parts of lily, 1-10 parts of lotus seeds, and 1-10 parts of jujube.

[0015] Further preferably, the weight ratio of the raw materials is: 5-10 parts of broom flower, 5-10 parts of black ginseng, 5-10 parts of astragalus, 5-10 parts of polygonatum, 1-5 parts of angelica, 1-5 parts of wolfberry, 1-5 parts of lily, 1-5 parts of lotus seeds, and 1-5 parts of jujube.

[0016] More preferably, the weight ratio of the raw materials is: 6 parts of thread-leaved broom, 6 parts of black ginseng, 6 parts of astragalus, 6 parts of polygonatum, 3 parts of angelica, 3 parts of wolfberry, 3 parts of lily, 3 parts of lotus seeds, and 3 parts of jujube.

[0017] In addition, the nutritional composition is characterized in that the oral preparation is an oral liquid, emulsion, syrup, powder, tablet, capsule, or pill; preferably an oral liquid.

[0018] On the other hand, the present invention also provides a method for preparing the above composition, the preparation method comprising:

[0019] (1) Extract broom, astragalus, angelica, polygonatum, wolfberry, lily, lotus seed, and jujube with water, filter out the precipitate, concentrate to obtain an extract, dry, grind and prepare powder;

[0020] (2) Crush the black ginseng medicinal material directly into powder.

[0021] (3) Stir and mix the powders obtained in steps (1) and (2) until they are uniform.

[0022] In yet another aspect, the present invention provides use of the above-mentioned composition in the preparation of a nutritional preparation for improving blood deficiency malnutrition.

[0023] The composition of the present invention can effectively improve the symptoms of decreased white blood cells, red blood cells and hemoglobin, as well as physical weakness caused by insufficient qi and blood, and plays the role of replenishing qi and blood, improving immunity and enhancing physical strength. DETAILED DESCRIPTION

[0024] The present invention is further described in detail below in conjunction with specific embodiments. The given examples are only for illustrating the present invention, but not for limiting the scope of the present invention.

[0025] Example 1: Preparation of raw material powder of nutritional composition

[0026] (1) 500 g each of Broom, Astragalus, and Polygonatum, and 300 g each of Angelica, Lycium barbarum, Lilium, Lotus seed, and Jujube were decocted in water for 3 times, each time using 5000 ml of water for 1.5 hours, and the water extract was filtered;

[0027] (2) respectively concentrating the extract under reduced pressure to a thick paste with a density of 1.06;

[0028] (3) drying the concentrated liquids under reduced pressure at a drying temperature of 70° C.; crushing the concentrated liquids and sieving them through an 80-mesh sieve to obtain dry powders of the raw materials;

[0029] (4) Take 500 g of black ginseng medicinal material, crush it to a particle size of 1-10 nm, and make it into ultrafine powder.

[0030] Example 2: Preparation of nutritional composition (ratio 1) oral liquid

[0031] Weigh 20 g of the broom extract, 20 g of astragalus extract, 20 g of polygonatum extract, 1 g of angelica extract, 1 g of wolfberry extract, 1 g of lily extract, 1 g of lotus seed extract, and 1 g of jujube extract prepared according to the method of Example 1, mix with 20 g of black ginseng superfine powder, add water to 300 mL, stir to mix, and dispense into 30 mL glass bottles, seal, and sterilize at high temperature.

[0032] Example 3: Preparation of nutritional composition (ratio 2) oral liquid

[0033] Weigh 3 g of the broom extract, 3 g of astragalus extract, 3 g of polygonatum extract, 10 g of angelica extract, 10 g of wolfberry extract, 10 g of lily extract, 10 g of lotus seed extract, and 10 g of jujube extract prepared according to the method of Example 1, mix with 3 g of black ginseng superfine powder, add water to 220 mL, stir to mix, and dispense into 30 mL glass bottles, seal, and sterilize at high temperature.

[0034] Example 4: Preparation of nutritional composition (ratio 3) oral liquid

[0035] Weigh 6 g of the broom extract, 6 g of astragalus extract, 6 g of polygonatum extract, 3 g of angelica extract, 3 g of wolfberry extract, 3 g of lily extract, 3 g of lotus seed extract, and 3 g of jujube extract prepared according to the method of Example 1, mix with 6 g of black ginseng superfine powder, add water to 138 mL, stir to mix, and dispense into 30 mL glass bottles, seal, and sterilize at high temperature.

[0036] Example 5: Comparative study of different compositions

[0037] 1. Experimental Materials

[0038] 1.1. Nutritional combination group

[0039] Composition 1: The extract of Broomrape filamentosa was prepared into a 0.23 g / mL suspension with distilled water before use and administered to mice by gavage.

[0040] Composition 2: 6 parts of ultrafine black ginseng powder, 6 parts of astragalus extract, 6 parts of polygonatum extract, 3 parts of angelica extract, and 3 parts of wolfberry extract, mixed evenly. Before use, distilled water was used to prepare a 0.23g / mL suspension for oral administration to mice.

[0041] Composition 3: 3 parts of lily extract, 3 parts of lotus seed extract, and 3 parts of jujube extract, mixed evenly, and prepared into a 0.23 g / mL suspension with distilled water before use, and used for oral administration to mice.

[0042] Composition 4: 6 parts of Broom extract, 6 parts of Black Ginseng superfine powder, 6 parts of Astragalus extract, 6 parts of Polygonatum sibiricum extract, 3 parts of Angelica extract, 3 parts of Lycium barbarum extract, 3 parts of Lilium extract, 3 parts of Lotus seed extract, 3 parts of Jujube extract, mix well. Prepare into 0.23g / mL suspension with distilled water before use, and use for mice by gavage.

[0043] 1.2 Animals

[0044] ICR mice, half male and half female, SPF grade, were provided by Sibeifu (Beijing) Biotechnology Co., Ltd., animal qualification certificate number SCXK (Beijing) 2024-0001.

[0045] 1.3 Instruments

[0046] Veterinary blood analyzer (Hemavet 950), Drew Scientific, USA.

[0047] High-speed refrigerated centrifuge (Sorvall ST 8R), Thermo Fisher Scientific (China) Co., Ltd.

[0048] 2. Experimental Methods

[0049] Model preparation: 50 SPF healthy mice were used for hemorrhagic anemia model preparation. 8-10 drops (about 0.2 ml) of blood were collected from the orbits of 50 mice on the day of model establishment and on the 3rd, 5th and 7th days after model establishment.

[0050] Grouping and administration: The modeling mice were randomly divided into 5 groups after bleeding on the first day, namely, the model group, the composition group 1, the composition group 2, the composition group 3, and the composition group 4, with 10 mice in each group. The model group was gavaged with distilled water, the composition group 1 was gavaged with 2.3 g / kg body weight of the suspension of the composition group 1, the composition group 2 was gavaged with 2.3 g / kg body weight of the suspension of the composition group 2, the composition group 3 was gavaged with 2.3 g / kg body weight of the suspension of the composition group 3, and the composition group 4 was gavaged with 2.3 g / kg body weight of the suspension of the composition group 4, with a gavage volume of 10 mL / kg body weight, once a day, for 7 consecutive days.

[0051] Index determination: The mice were bled from their orbits and collected in EDTA anticoagulation centrifuge tubes and mixed. After each blood draw, the red blood cell count and hemoglobin content were measured using a fully automatic blood cell analyzer for animals. The results were statistically analyzed using one-way analysis of variance.

[0052] 3. Experimental results

[0053] ① Changes in red blood cell count

[0054] There was no significant difference in red blood cell count (normal value) among the groups before modeling.

[0055] The red blood cell counts of mice in the model group were significantly lower than the normal values ​​on the 3rd, 5th and 7th days after orbital bleeding (P<0.05, P<0.01). Compared with the model group, the red blood cell counts of group 1 were significantly increased on the 7th day after intragastric administration (P<0.05); the red blood cell counts of group 2 were significantly increased on the 5th and 7th days after intragastric administration (P<0.05, P<0.01); the red blood cell counts of group 3 were significantly increased on the 7th day after intragastric administration (P<0.01); the red blood cell counts of group 4 were significantly increased on the 3rd, 5th and 7th days after intragastric administration (P<0.05, P<0.01).

[0056] On the third day after oral administration, the red blood cell count in group 4 was significantly increased compared with that in groups 1, 2 and 3 (P<0.05).

[0057] The results show that the effect of composition 4 on increasing red blood cell count is faster and more potent than that of composition 1, composition 2 and composition 3. The results are shown in Table 1.

[0058] Table 1 Red blood cell count (RBC) results

[0059]

[0060]

[0061] Note: Compared with normal values, # represents P < 0.05, ## Represents P < 0.01; compared with the model group,* represents P < 0.05, ** Represents P < 0.01; compared with composition 1, △ Represents P < 0.05; compared with composition 2, ☆ Represents P < 0.05; compared with composition 3, § Represents P<0.05.

[0062] ② Changes in hemoglobin content

[0063] There was no significant difference in the hemoglobin content (normal value) among the groups before modeling.

[0064] The hemoglobin content of mice in the model group was significantly lower than the normal value on the 3rd, 5th and 7th days after orbital bleeding (P<0.01). Compared with the model group, the hemoglobin content of group 1 was significantly increased on the 7th day after intragastric administration (P<0.01); the hemoglobin content of group 2 was significantly increased on the 5th and 7th days after intragastric administration (P<0.05, P<0.01); the hemoglobin content of group 3 was significantly increased on the 7th day after intragastric administration (P<0.01); the hemoglobin content of group 4 was significantly increased on the 3rd, 5th and 7th days after intragastric administration (P<0.01).

[0065] On the third day after oral administration of mice, the hemoglobin content in group 4 was significantly increased compared with that in groups 1, 2 and 3 (P<0.05).

[0066] The results show that the effect of composition 4 on increasing the hemoglobin content is faster and more potent than that of composition 1, composition 2, and composition 3. The results are shown in Table 2.

[0067] Table 2 Hemoglobin (HGB) results

[0068]

[0069] Note: Compared with normal values, ## Represents P < 0.01; compared with the model group, * Mean P < 0.05 ，** Represents P < 0.01; compared with composition 1, △ Represents P < 0.05; compared with composition 2, ☆ Represents P < 0.05; compared with composition 3, § Represents P<0.05.

[0070] In summary, the whole formula composition 4 has the effect of replenishing and nourishing blood, can increase red blood cell count and hemoglobin content, and has a faster onset and stronger effect than the separated formula composition group 1, composition group 2, and composition group 3.

[0071] Example 6: Protective effect of the composition on blood system damage caused by cyclophosphamide

[0072] 1. Experimental Materials

[0073] 1.1 Experimental samples

[0074] Composition: 6 parts of Broom extract, 6 parts of Black Ginseng superfine powder, 6 parts of Astragalus extract, 6 parts of Polygonatum sibiricum extract, 3 parts of Angelica extract, 3 parts of Lycium barbarum extract, 3 parts of Lilium extract, 3 parts of Lotus seed extract, 3 parts of Jujube extract, mix well. Before use, prepare 3 kinds of suspensions of 0.12mg / mL, 0.23g / mL, and 0.46g / mL with distilled water respectively, and use them for oral administration of mice.

[0075] Danggui Buxue Decoction: The prescription comes from Li Dongyuan's "Discussion on Internal and External Injuries" in the Yuan Dynasty. Take 5 parts of the Astragalus extract in Example 1 and 1 part of the Angelica extract, mix them evenly. Before use, distilled water is used to prepare a 0.23g / mL suspension for oral administration to mice.

[0076] 1.2 Reagents

[0077] Cyclophosphamide (CTX) for injection, Baxter Oncology GmbH, Germany, batch number: 01407A.

[0078] 1.3 Instruments

[0079] High-speed refrigerated centrifuge (Sorvall ST 8R), Thermo Fisher Scientific (China) Co., Ltd.

[0080] Veterinary blood analyzer (Hemavet 950), Drew Scientific, USA.

[0081] 1.4 Animals

[0082] ICR mice, half male and half female, SPF grade, were provided by Sibeifu (Beijing) Biotechnology Co., Ltd., animal qualification certificate number SCXK (Beijing) 2024-0001.

[0083] 2. Experimental Methods

[0084] 60 SPF healthy mice were selected, 10 of which were used as the normal group, and the remaining 50 mice were intraperitoneally injected with 40 mg / kg of cyclophosphamide for 3 consecutive days. After the first injection of cyclophosphamide, they were randomly divided into 5 groups, namely the model group, the low-dose group, the medium-dose group, the high-dose group of the combination, and the Angelica Blood-Supplementing Decoction group. Together with the normal group, there were 6 groups in total, with 10 mice in each group. After the first injection of cyclophosphamide, each group began to be gavaged with the experimental samples, and the normal group and the model group were gavaged with distilled water; the low-, medium-, and high-dose groups of the combination were gavaged with 1.2, 2.3, and 4.6 g / kg body weight of the combination, respectively; the Angelica Blood-Supplementing Decoction group was gavaged with 2.3 g / kg body weight of Angelica Blood-Supplementing Decoction; the gavage volume was 10 mL / kg body weight, and it was gavaged once a day for 7 consecutive days.

[0085] One hour after the last intragastric administration, the mice were bled from their orbits and collected in EDTA anticoagulation centrifuge tubes and mixed. The leukocyte count, erythrocyte count, and hemoglobin content were measured using a fully automatic blood cell analyzer for animals. The results were statistically analyzed using one-way analysis of variance.

[0086] 3. Experimental results

[0087] The results showed that the low, medium and high dose groups of the combination group could significantly increase the white blood cell count, red blood cell count and hemoglobin content. The medium and high dose groups of the combination group had a stronger effect than Danggui Buxue Decoction, with significant differences (P<0.05, P<0.01). See Table 3 for details.

[0088] Table 3 Peripheral blood changes

[0089]

[0090]

[0091] Note: Compared with the normal group, ## = ... △ represents P < 0.05, △△ Represents P<0.01.

[0092] In summary, the whole formula has the effect of nourishing blood, can increase white blood cell count, red blood cell count, and hemoglobin content, and the intensity of the effect is better than the ancient classic formula Danggui Buxue Decoction.

[0093] Example 7: Effect of the composition on enhancing physical strength

[0094] 1. Experimental Materials

[0095] 1.1 Experimental samples

[0096] Composition: 6 parts of Broom extract, 6 parts of Black Ginseng superfine powder, 6 parts of Astragalus extract, 6 parts of Polygonatum sibiricum extract, 3 parts of Angelica extract, 3 parts of Lycium barbarum extract, 3 parts of Lilium extract, 3 parts of Lotus seed extract, 3 parts of Jujube extract, mix well. Before use, prepare 3 kinds of suspensions of 0.12mg / mL, 0.23g / mL, and 0.46g / mL with distilled water respectively, and use them for oral administration of mice.

[0097] Danggui Buxue Decoction: The prescription comes from Li Dongyuan's "Discussion on Internal and External Injuries" in the Yuan Dynasty. Take 5 parts of the Astragalus extract in Example 1 and 1 part of the Angelica extract, mix them evenly. Before use, distilled water is used to prepare a 0.23g / mL suspension for oral administration to mice.

[0098] 1.2 Instruments

[0099] Swimming box: homemade.

[0100] 1.3 Animals

[0101] ICR mice, half male and half female, SPF grade, were provided by Sibeifu (Beijing) Biotechnology Co., Ltd., animal qualification certificate number SCXK (Beijing) 2024-0001.

[0102] 2. Experimental Methods

[0103] 50 mice were randomly divided into 5 groups, namely, control group, low-dose group, medium-dose group, high-dose group of the composition, and Danggui Buxue Decoction group, with 10 mice in each group. The control group was gavaged with distilled water, the low-dose group, medium-dose group, and high-dose group of the composition were gavaged with 1.2, 2.3, and 4.6 g / kg body weight of the composition, respectively; the Danggui Buxue Decoction group was gavaged with 2.3 g / kg body weight of Danggui Buxue Decoction; the gavage volume was 10 mL / kg body weight, once a day, for 7 consecutive days.

[0104] One hour after the last gavage, a paper clip weighing 5% of the mouse's body weight was placed at the base of the mouse's tail and placed in a swimming box with a water depth of 35 cm and a water temperature of 25°C. The swimming time of each group of mice was recorded, i.e., the time from the start of swimming to sinking to the bottom of the swimming box and stopping mouth breathing. The results were statistically analyzed using one-way analysis of variance.

[0105] 3. Experimental results

[0106] The mice were gavaged with the composition for 7 days. Compared with the control group, the medium-dose group and the high-dose group of the composition could significantly prolong the swimming time (P<0.05, P<0.01). Compared with the Danggui Buxue Decoction group, the high-dose group of the composition had a more significant effect in prolonging the swimming time (P<0.05), indicating that the effect of enhancing physical strength was better than that of the Danggui Buxue Decoction group. See Table 4 for details.

[0107] Table 4 Effect of the composition on the swimming time of mice

[0108]

[0109] Note: Compared with the control group, * represents P < 0.05, ** Represents P<0.01.

[0110] In summary, the whole formula combination can significantly prolong the swimming time of mice, indicating that the whole formula combination has the effect of enhancing physical strength, and its effect is better than Danggui Buxue Decoction.

[0111] Discussion: According to TCM theory, Qi can generate blood, and blood can carry Qi. The composition can increase the white blood cell count, red blood cell count, and hemoglobin content, reflecting the effect of nourishing blood; at the same time, the composition can increase swimming time and enhance physical strength, indicating that the composition has the effect of replenishing Qi.

Claims

1. A medicinal and edible nutritional composition with the effects of invigorating qi and nourishing blood, the composition being prepared from the following raw materials: broom flower, black ginseng, astragalus, polygonatum, angelica, wolfberry, lily, lotus seeds, and jujube.

2. The nutritional composition according to claim 1, characterized in that The weight ratio of the raw materials is: 3-20 parts of thread-leaf broom, 3-20 parts of black ginseng, 3-20 parts of astragalus, 3-20 parts of polygonatum, 1-10 parts of angelica, 1-10 parts of wolfberry, 1-10 parts of lily, 1-10 parts of lotus seeds, and 1-10 parts of jujube.

3. The nutritional composition according to claims 1-2, characterized in that The weight ratio of the raw materials is preferably: 5-10 parts of thread-leaved broom, 5-10 parts of black ginseng, 5-10 parts of astragalus, 5-10 parts of polygonatum, 1-5 parts of angelica, 1-5 parts of wolfberry, 1-5 parts of lily, 1-5 parts of lotus seeds, and 1-5 parts of jujube.

4. The nutritional composition according to claims 1-3, characterized in that The weight ratio of the raw materials is more preferably: 6 parts of thread-leaved broom, 6 parts of black ginseng, 6 parts of astragalus, 6 parts of polygonatum, 3 parts of angelica, 3 parts of wolfberry, 3 parts of lily, 3 parts of lotus seeds, and 3 parts of jujube.

5. The nutritional composition according to any one of claims 1 to 4, characterized in that The invention can be prepared into any pharmaceutically acceptable oral dosage form.

6. The nutritional composition according to claim 5, characterized in that The oral preparation is oral liquid, emulsion, syrup, powder, tablet, capsule, pill; oral liquid is preferred.

7. A method for preparing the composition according to any one of claims 1 to 4, comprising: (1) Extracting broom, astragalus, angelica, polygonatum, wolfberry, lily, lotus seed, and jujube with water respectively, filtering out the precipitate, concentrating to obtain an extract, drying, and crushing to obtain a powder; (2) Crush the black ginseng medicinal material directly into powder. (3) Stir and mix the powder obtained in steps (1) and (2) until it is uniform.

8. Use of the nutritional composition according to any one of claims 1 to 4 in the preparation of a nutritional preparation for improving qi and blood deficiency.

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