Anti-wrinkle essence and preparation method thereof

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to anti-wrinkle essence water and a preparation method thereof.The anti-wrinkle essence water is mainly capable of achieving the anti-wrinkle and skin care effects due to combination of multiple anti-wrinkle components in the anti-wrinkle essence water, the anti-wrinkle essence water has the effects of promoting skin metabolism, resisting oxidation and reducing inflammation due to matching of the different components in the anti-wrinkle essence water, and the anti-wrinkle essence water is free of side effects. The composition promotes synthesis of collagen by enhancing metabolism and promoting cell regeneration so as to improve skin laxity and wrinkles, improve skin compactness and achieve an anti-aging effect, reduces formation of fine wrinkles and wrinkles by resisting oxidation and neutralizing free radicals, reduces skin inflammation, regulates skin micro-ecology and slows down skin aging by resisting inflammation, and has a good anti-aging effect. In addition, the anti-wrinkle essence water also contains a plurality of moisturizing and soothing components, and the anti-wrinkle, moisturizing and soothing effects are mutually combined and mutually promoted.

Description

Technical Field

[0001] The invention belongs to the technical field of cosmetics, and particularly relates to an anti-wrinkle essence water and a preparation method thereof. Background Art

[0002] In the cosmetics field, essence water is a toner with skin care functions. It contains moisturizing ingredients, plant extracts, etc. It can be used to soothe the skin, moisturize the skin, help balance the pH value of the skin, and keep the skin moisturized after cleansing. Due to the formula of the current essence water, its moisturizing, soothing, and especially anti-wrinkle and skin vitality promotion needs to be improved. Summary of the invention

[0003] The present invention aims to provide an anti-wrinkle essence water and a preparation method thereof. The anti-wrinkle essence water adopts different anti-wrinkle mechanism components and has good effects in anti-wrinkle and promoting skin vitality. Moreover, the product will not cause harm to human health under normal, reasonable and foreseeable use conditions.

[0004] To achieve the above objectives, the present invention adopts the following technical solutions:

[0005] Provided is an anti-wrinkle essence water, which is composed of the following materials in parts by weight:

[0006] Water 86.9731-106.3005 parts;

[0007] 0.9023 to 1.1028 parts of 1,2-pentanediol;

[0008] Glucuronic acid 0.4725-0.5775 parts;

[0009] Propylene glycol 0.3042-0.3718 parts;

[0010] 1,3-propylene glycol 0.2633-0.3218 parts;

[0011] Mannose 0.25-0.31 parts;

[0012] 1,2-hexanediol 0.1771-0.2164 parts;

[0013] 0.152-0.186 parts of butanediol;

[0014] Methylpropanediol 0.117-0.143 parts;

[0015] β-glucan 0.0945-0.1155 parts;

[0016] Lactobionic acid 0.063-0.077 parts;

[0017] 0.045-0.055 parts of sodium citrate;

[0018] PEG-40 hydrogenated castor oil 0.0338-0.0413 parts;

[0019] Ethylhexylglycerin 0.0217-0.0265 parts;

[0020] 0.0203-0.0248 parts of octanoylhydroxamic acid;

[0021] 0.018-0.022 parts of budding short-stalked enzyme polysaccharide;

[0022] 0.0158 to 0.0193 parts of p-hydroxyacetophenone;

[0023] Phenoxyethanol 0.0143-0.0175 parts;

[0024] 0.0126-0.0154 parts of o-cymene-5-ol;

[0025] Biosaccharide gum-1 0.0099~0.0121 parts;

[0026] 0.009045 to 0.011055 parts of citric acid;

[0027] 0.009-0.011 parts of glycerophosphoinositol choline salt;

[0028] 0.0054-0.0066 parts of thyme extract;

[0029] 0.003375-0.004125 parts of clove bud extract;

[0030] 0.003375-0.004125 parts of Litsea cubeba fruit oil;

[0031] 0.00225-0.00275 parts of Nannochloropsis oculata extract;

[0032] Sodium hyaluronate 0.0018-0.0022 parts;

[0033] Carbomer 0.001584-0.00176 parts;

[0034] Polysorbate-20 0.0009-0.0011 parts;

[0035] Caprylyl glycol 0.000594 to 0.000726 parts;

[0036] 0.000405-0.000495 parts of Sophora flavescens root extract;

[0037] Xanthan gum 0.000108-0.000132 parts;

[0038] Fullerene 0.000081 to 0.000099 parts;

[0039] Palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 0.000018~0.000022 parts; Palmitoyl tetrapeptide-7 0.000009~0.000011 parts.

[0040] Preferably, the anti-wrinkle essence water is composed of the following materials in parts by weight: 96.6368 parts of water;

[0041] 1,2-pentanediol 1.0025 parts;

[0042] Glucuronic acid 0.525 parts;

[0043] Propylene glycol 0.338 parts;

[0044] 0.2925 parts of 1,3-propylene glycol;

[0045] Mannose 0.28 parts;

[0046] 0.1967 parts of 1,2-hexanediol;

[0047] Butanediol 0.169 parts;

[0048] Methylpropanediol 0.13 parts;

[0049] β-glucan 0.105 parts;

[0050] Lactobionic acid 0.07 parts;

[0051] 0.05 parts of sodium citrate;

[0052] PEG-40 hydrogenated castor oil 0.0375 parts; Ethylhexylglycerin 0.0241 parts;

[0053] 0.0225 parts of octanoylhydroxamic acid;

[0054] 0.02 parts of budding short-stalked enzyme polysaccharide;

[0055] 0.0175 parts of p-hydroxyacetophenone;

[0056] Phenoxyethanol 0.0159 parts;

[0057] 0.014 parts of o-cymene-5-ol;

[0058] Biosaccharide Gum-1 0.011 parts;

[0059] 0.01005 parts of citric acid;

[0060] 0.01 part of glycerophosphoinositol choline salt; 0.006 parts of thyme extract; 0.00375 parts of clove bud extract; 0.00375 parts of Litsea cubeba fruit oil;

[0061] 0.0025 parts of Nannochloropsis oculata extract;

[0062] 0.002 parts of sodium hyaluronate;

[0063] Carbomer 0.0016 parts;

[0064] Polysorbate-20 0.001 parts;

[0065] Caprylyl glycol 0.00066 parts;

[0066] Sophora flavescens root extract 0.00045 parts;

[0067] Xanthan gum 0.00012 parts;

[0068] Fullerene 0.00009 parts;

[0069] Palmitoyl Tripeptide-1 / Palmitoyl Hexapeptide-12 0.00002 parts;

[0070] Palmitoyl Tetrapeptide-7 0.00001 parts.

[0071] Preferably, the European thyme extract is an extract obtained by squeezing and extracting the European thyme plant;

[0072] The clove bud extract is an extract obtained by squeezing and extracting clove buds;

[0073] The Nannochloropsis oculata extract is an extract obtained by squeezing and extracting Nannochloropsis oculata;

[0074] The Sophora flavescens root extract is an extract obtained by squeezing and extracting the Sophora flavescens root.

[0075] Preferably, the extraction method of the thyme extract, the clove bud extract, the Nannochloropsis oculata extract and the Sophora flavescens root extract is carbon dioxide supercritical extraction.

[0076] The present invention also provides a method for preparing the aforementioned anti-wrinkle essence water, comprising:

[0077] Prepare various weight portions of raw materials for preparing the anti-wrinkle essence water;

[0078] Take the prepared glucuronic acid, mannose, β-glucan, lactobionic acid, appropriate amount of 1,2-hexanediol, p-hydroxyacetophenone and appropriate amount of water and mix them well as the first moisturizing agent;

[0079] Take the prepared appropriate amount of phenoxyethanol, biosaccharide gum-1 and appropriate amount of water and mix them evenly as the first skin conditioning agent for later use;

[0080] Take the prepared 1,3-propylene glycol, an appropriate amount of 1,2-hexanediol, and octanoylhydroxamic acid and mix them evenly as a chelating agent;

[0081] Take the prepared propylene glycol, an appropriate amount of ethylhexylglycerin, an appropriate amount of 1,2-hexanediol, and o-cymene-5-ol and mix them evenly as a preservative;

[0082] Take the prepared PEG-40 hydrogenated castor oil, thyme extract, clove bud extract, Litsea cubeba fruit oil, appropriate amount of 1,2-hexanediol, caprylyl glycol, Sophora flavescens root extract and appropriate amount of water and mix well as the second skin conditioning agent for use;

[0083] Take the prepared butanediol, xanthan gum, fullerene, an appropriate amount of methyl propanediol and an appropriate amount of water and mix them evenly as an antioxidant for later use;

[0084] Take appropriate amount of prepared methylpropanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7 and appropriate amount of water and mix well as the third skin conditioning agent for use;

[0085] Take the prepared glycerophosphoinositol choline salt, an appropriate amount of phenoxyethanol, an appropriate amount of ethylhexylglycerin and an appropriate amount of water and mix them evenly as the fourth skin conditioning agent for later use;

[0086] Take the prepared budding short-stalked enzyme polysaccharide, Nannochloropsis oculiformis extract, 1,2-pentanediol, appropriate amount of citric acid and appropriate amount of water and mix them evenly as the fifth skin conditioning agent for use;

[0087] The first skin conditioner, chelating agent, preservative, second skin conditioner, antioxidant, third skin conditioner, fourth skin conditioner, fifth skin conditioner and other remaining raw materials are mixed and packaged to obtain the anti-wrinkle essence water.

[0088] Compared with the prior art, the beneficial effects of the present invention are as follows: the combination of multiple anti-wrinkle ingredients in the anti-wrinkle essence water enables it to mainly play the role of anti-wrinkle and skin care. Among them, the combination of different components in the anti-wrinkle essence water enables it to have the effects of promoting skin metabolism, anti-oxidation, and reducing inflammation. It improves skin sagging and wrinkles by enhancing metabolism and promoting cell regeneration to promote the synthesis of collagen, enhance skin firmness, and achieve anti-aging effects. It reduces the formation of fine lines and wrinkles by neutralizing free radicals through anti-oxidation, reduces skin inflammation through anti-inflammatory, regulates skin microecology, slows down skin aging, and reduces the formation of wrinkles. In addition, the anti-wrinkle essence water also has a variety of moisturizing and soothing ingredients, and the anti-wrinkle, moisturizing and soothing effects are combined with each other and promote each other. DETAILED DESCRIPTION

[0089] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0090] Example 1: An anti-wrinkle essence water

[0091] The anti-wrinkle essence water is composed of the following materials in parts by weight: 86.9731 parts of water; 0.9023 parts of 1,2-pentanediol; 0.4725 parts of glucuronic acid; 0.3042 parts of propylene glycol; 0.263 parts of 1,3-propanediol; 0.25 parts of mannose; 0.1771 parts of 1,2-hexanediol; 0.152 parts of butylene glycol; 0.117 parts of methylpropanediol; 0.0945 parts of β-glucan; 0.063 parts of lactobionic acid; 0.045 parts of sodium citrate; 0.0338 parts of PEG-40 hydrogenated castor oil; 0.0217 parts of ethylhexylglycerin; 0.0203 parts of caprylhydroxamic acid 0.018 parts of budding short pedunculate polysaccharide; 0.0158 parts of p-hydroxyacetophenone; 0.0143 parts of phenoxyethanol; 0.0126 parts of o-cymene-5-ol; 0.0099 parts of biosaccharide gum-1; 0.009045 parts of citric acid; 0.009 parts of glycerophosphoinositol choline salt; 0.0054 parts of thyme extract; 0.003375 parts of clove bud extract; 0.003375 parts of mountain pepper fruit oil; 0.00225 parts of eye-shaped vein microcystis extract; 0.0018 parts of sodium hyaluronate; 0.001584 parts of carbomer; polysorbate-20 0.0009 parts; caprylyl glycol 0.000594 parts; Sophora flavescens root extract 0.000405 parts; xanthan gum 0.000108 parts; fullerene 0.000081 parts; palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 0.000018 parts; palmitoyl tetrapeptide-7 0.000009 parts. Palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 here is a mixture of the two, each of which is 0.000009 parts.

[0092] The functions of various substances in the anti-wrinkle essence water are as follows: water is mainly used as a solvent, and water is also used to prepare other components. Glucuronic acid, mannose, β-glucan, lactobionic acid, an appropriate amount of 1,2-hexanediol, p-hydroxyacetophenone and an appropriate amount of water are mixed as the first moisturizer. Glucuronic acid has moisturizing and exfoliating effects, mannitol has moisturizing, antibacterial and antioxidant effects, β-glucan has moisturizing, antibacterial, anti-allergic and anti-aging effects, 1,2-hexanediol has moisturizing, antibacterial and skin feel improvement effects, and p-hydroxyacetophenone has antibacterial effects. Water is used to prepare these substances together. An appropriate amount of phenoxyethanol, biosaccharide gum-1 and an appropriate amount of water are mixed as the first skin conditioning agent. The role of phenoxyethanol is antibacterial, and biosaccharide gum-1 has the effects of soothing the skin, moisturizing, stabilizing cell protein structure, soothing and anti-allergic. Water is used to prepare these two substances together. 1,3-propylene glycol, appropriate amount of 1,2-hexanediol, and caprylhydroxamic acid are mixed as chelating agents, which are used to stabilize the formula, resist oxidation, and adjust the pH value. Propylene glycol, appropriate amount of ethylhexylglycerol, appropriate amount of 1,2-hexanediol, and o-cymene-5-ol are mixed as preservatives. Preservatives have antibacterial effects, and different ingredients have different antibacterial targets. PEG-40 hydrogenated castor oil, thyme extract, clove bud extract, Litsea cubeba fruit oil, appropriate amount of 1,2-hexanediol, caprylyl glycol, Sophora flavescens root extract and appropriate amount of water are mixed as the second skin conditioning agent. PEG-40 hydrogenated castor oil has the function of enhancing skin elasticity and moisturizing and locking moisture. Thyme extract has anti-inflammatory, antioxidant, antibacterial and anti-wrinkle effects. Clove bud extract has anti-inflammatory and anti-aging effects. Litsea cubeba fruit oil has the effect of conditioning odor, moisturizing and degreasing. 1,2-hexanediol has antibacterial and moisturizing effects. Caprylyl glycol has moisturizing and antibacterial and softening and soothing effects. Sophora flavescens root extract has anti-inflammatory and whitening effects. Water is used to mix other components together. Butylene glycol, xanthan gum, fullerene, appropriate amount of methyl propanediol and appropriate amount of water are mixed as antioxidants. Antioxidants are used to prevent oil components from being oxidized and deteriorated. An appropriate amount of methylpropanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7 and an appropriate amount of water are mixed as the third skin conditioning agent, wherein methylpropanediol is used as a solvent and has the effect of moisturizing and emollient, carbomer is a thickener, polysorbate-20 is an emulsifier, and palmitoyl polypeptide can improve skin elasticity, moisturize the skin, reduce inflammation and promote collagen synthesis. Glyceryl phosphoinositol choline salt, an appropriate amount of phenoxyethanol, an appropriate amount of ethylhexylglycerol and an appropriate amount of water are mixed as the fourth skin conditioning agent, glyceryl phosphoinositol choline salt has anti-allergic, anti-inflammatory and anti-drying effects, phenoxyethanol has anti-inflammatory and antioxidant effects, ethylhexylglycerol has moisturizing, emollient and antibacterial effects, and water is used to mix the other raw materials together.Budding short-stalked enzyme polysaccharide, Nannochloropsis oculi extract, 1,2-pentanediol, an appropriate amount of citric acid and an appropriate amount of water are mixed as the fifth skin conditioning agent. Budding short-stalked enzyme polysaccharide has moisturizing, regeneration and antioxidant effects, Nannochloropsis oculi extract has antioxidant, anti-aging and moisturizing effects, 1,2-pentanediol can regulate skin texture, moisturize and antibacterial, citric acid has the effects of exfoliation, whitening and anti-inflammatory, and water is used to mix several other raw materials together. The remaining other substances in the anti-wrinkle essence water have the following functions: water is mainly used as a solvent; 1,2-pentanediol is used as a moisturizer; sodium citrate is used as a pH regulator; citric acid is used as a pH regulator; sodium hyaluronate is used as a moisturizer.

[0093] All components in the anti-wrinkle essence water can use raw materials purchased on the market, because the properties of these raw materials produced by various manufacturers are basically the same, so the purchase source does not need to be limited, only the corresponding types and weights of raw materials are needed. However, some raw materials can also be made by yourself, and some of the materials are obtained as follows: European thyme extract is an extract obtained by squeezing and extracting European thyme plants. European thyme is thyme, and the extract obtained by squeezing and extracting European thyme licorice can be extracted by supercritical carbon dioxide extraction. Clove bud extract is an extract obtained by squeezing and extracting clove buds, and specifically, the clove buds can be crushed and squeezed and then extracted by supercritical carbon dioxide extraction. Eye-shaped vein micro-chlorophyll extract is an extract obtained by squeezing and extracting eye-shaped vein micro-chlorophyll, and specifically, the eye-shaped vein micro-chlorophyll is squeezed and then extracted by supercritical carbon dioxide extraction. Sophora flavescens root extract is an extract obtained by squeezing and extracting Sophora flavescens roots, and the Sophora flavescens roots are squeezed and extracted by supercritical carbon dioxide extraction.

[0094] The preparation method of the anti-wrinkle essence water is as follows: (1) first prepare the raw materials for preparing the anti-wrinkle essence water in parts by weight, wherein the raw materials are as follows in parts by weight: 86.9731 parts of water; 0.9023 parts of 1,2-pentanediol; 0.4725 parts of glucuronic acid; 0.3042 parts of propylene glycol; 0.263 parts of 1,3-propanediol; 0.25 parts of mannose; 0.1771 parts of 1,2-hexanediol; 0.152 parts of butylene glycol; 0.117 parts of methylpropanediol; 0.0945 parts of β-glucan; 0.063 parts of lactobionic acid; 0.045 parts of sodium citrate; 0.0338 parts of PEG-40 hydrogenated castor oil; 0.063 parts of ethylhexylglycerin; .0217 parts; 0.0203 parts of caprylhydroxamic acid; 0.018 parts of budding short pedunculate polysaccharide; 0.0158 parts of p-hydroxyacetophenone; 0.0143 parts of phenoxyethanol; 0.0126 parts of o-cymene-5-ol; 0.0099 parts of biosaccharide gum-1; 0.009045 parts of citric acid; 0.009 parts of glycerophosphoinositol choline salt; 0.0054 parts of thyme extract; 0.003375 parts of clove bud extract; 0.003375 parts of mountain pepper fruit oil; 0.00225 parts of eye-shaped vein microcystis extract; 0.0018 parts of sodium hyaluronate; 0.001584 parts of carbomer; polysorbate-20 0.0009 parts; caprylyl glycol 0.000594 parts; Sophora flavescens root extract 0.000405 parts; xanthan gum 0.000108 parts; fullerene 0.000081 parts; palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 0.000018 parts; palmitoyl tetrapeptide-7 0.000009 parts. Palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 here is a mixture of the two, each of which is 0.000009 parts.

[0095] (2) Take the prepared glucuronic acid, mannose, β-glucan, lactobionic acid, an appropriate amount of 1,2-hexanediol, p-hydroxyacetophenone and an appropriate amount of water and mix them as the first moisturizer; take the prepared appropriate amount of phenoxyethanol, biosaccharide gum-1 and an appropriate amount of water and mix them as the first skin conditioner for standby use; take the prepared 1,3-propylene glycol, an appropriate amount of 1,2-hexanediol, and caprylhydroxamic acid and mix them as a chelating agent; take the prepared propylene glycol, an appropriate amount of ethylhexylglycerin, an appropriate amount of 1,2-hexanediol, and o-cymene-5-ol and mix them as a preservative; take the prepared PEG-40 hydrogenated castor oil, thyme extract, clove bud extract, Litsea cubeba fruit oil, an appropriate amount of 1,2-hexanediol, caprylyl glycol, and Sophora flavescens root extract Mix the prepared butylene glycol, xanthan gum, fullerene, an appropriate amount of methylpropanediol and an appropriate amount of water as a second skin conditioning agent for use; mix the prepared butylene glycol, xanthan gum, fullerene, an appropriate amount of methylpropanediol and an appropriate amount of water as an antioxidant for use; mix the prepared appropriate amount of methylpropanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7 and an appropriate amount of water as a third skin conditioning agent for use; mix the prepared glycerophosphoinositol choline salt, an appropriate amount of phenoxyethanol, an appropriate amount of ethylhexylglycerin and an appropriate amount of water as a fourth skin conditioning agent for use; mix the prepared budding short pedunculate polysaccharide, eye-shaped vein microcystis extract, 1,2-pentanediol, an appropriate amount of citric acid and an appropriate amount of water as a fifth skin conditioning agent for use;

[0096] (3) The first skin conditioning agent, the chelating agent, the preservative, the second skin conditioning agent, the antioxidant, the third skin conditioning agent, the fourth skin conditioning agent, the fifth skin conditioning agent and the remaining other raw materials are mixed and packaged to obtain the anti-wrinkle essence water.

[0097] The safety of the amount of each weight portion of the anti-wrinkle essence water meets the requirements, among which:

[0098] In the field of cosmetics, the highest historical usage of water is 97.966% of the total raw material mass percentage, and in the formula of this anti-wrinkle essence water, the water used meets the national drinking water standards. The amount of water used is below the maximum amount and meets safety requirements.

[0099] The highest historical usage of β-glucan is 30% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of β-glucan added is not higher than the highest historical usage in the "Catalogue of Used Cosmetic Raw Materials" and can be used safely. The highest historical usage of glycerophosphoinositol choline salt is 0.32% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of glycerophosphoinositol choline salt added is not higher than the highest historical usage in the "Catalogue of Used Cosmetic Raw Materials" and can be used safely. The highest historical usage of European thyme extract is 3% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of European thyme extract added is not higher than the highest historical usage in the "Catalogue of Used Cosmetic Raw Materials" and can be used safely. The highest historical usage of clove bud extract is 0.985% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of clove bud extract added is not higher than the highest historical usage in the "Catalogue of Used Cosmetic Raw Materials" and can be used safely. The highest historical usage of Litsea cubeba fruit oil is 14.28% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of Litsea cubeba fruit oil added is not higher than the highest historical usage amount in the "Catalogue of Used Cosmetic Raw Materials", and it can be used safely. The highest historical usage of Chlorella oculata extract is 0.125% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of Chlorella oculata extract added is not higher than the highest historical usage amount in the "Catalogue of Used Cosmetic Raw Materials", and it can be used safely. The highest historical usage of Sophora flavescens root extract is 2.126% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of Sophora flavescens root extract added is not higher than the highest historical usage amount in the "Catalogue of Used Cosmetic Raw Materials", and it can be used safely. The highest historical usage of fullerene is 3% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of fullerene added is not higher than the highest historical usage amount in the "Catalogue of Used Cosmetic Raw Materials", and it can be used safely. The highest historical usage of palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 is 9% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 added is not higher than the highest historical usage in the "Catalogue of Used Cosmetic Raw Materials" and can be used safely. The highest historical usage of palmitoyl tetrapeptide-7 is 8% of the total raw material mass percentage. In the formula of this anti-wrinkle essence water, the total amount of palmitoyl tetrapeptide-7 added is not higher than the highest historical usage in the "Catalogue of Used Cosmetic Raw Materials" and can be used safely.

[0100] Regarding the use of glucuronic acid, lactobionic acid, sodium citrate and citric acid, the "Safety Technical Specification for Cosmetics" (2015 Edition) Restricted Ingredients for Cosmetics (Table 3) No. 37 stipulates: the maximum allowable total concentration when used in cosmetics is 6% (in acid terms); pH ≥ 3.5 (except for rinse-off hair products); if used in non-sunscreen skin care cosmetics, and contains ≥ 3% α-hydroxy acid or claims α-hydroxy acid on the label, it should be marked "for use with sunscreen cosmetics". In this anti-wrinkle essence water, the use scope and conditions of these raw materials in this formula meet the requirements of the "Safety Technical Specification for Cosmetics" (2015 Edition) and can be used safely.

[0101] Regarding the use of phenoxyethanol, the "Safety Technical Specifications for Cosmetics" (2015 Edition) "Approved Preservatives for Cosmetics (Table 4)" No. 37 stipulates that the limit of phenoxyethanol is 1%. In this anti-wrinkle essence water, the use scope and conditions of this raw material in this formula meet the requirements of the "Safety Technical Specifications for Cosmetics" (2015 Edition) and can be used safely.

[0102] Regarding the use of o-cymene-5-ol, the "Safety Technical Specifications for Cosmetics" (2015 Edition) Permitted Preservatives for Cosmetics (Table 4) No. 37 stipulates that the limited amount of o-cymene-5-ol is 0.1%. In this anti-wrinkle essence water, the use scope and conditions of this raw material in this formula meet the requirements of the "Safety Technical Specifications for Cosmetics" (2015 Edition) and can be used safely.

[0103] According to the evaluation results of the Cosmetic Ingredient Evaluation Committee (CIR) of the United States, 1,2-pentanediol is safe when used in leave-on cosmetics at a dosage of no more than 5%, propylene glycol is safe when used in leave-on cosmetics at a dosage of no more than 73%, 1,3-propylene glycol is safe when used in leave-on cosmetics at a dosage of no more than 39.9%, mannose is safe when used in leave-on cosmetics at a dosage of no more than 5%, 1,2-hexanediol is safe when used in leave-on cosmetics at a dosage of no more than 10%, butylene glycol is safe when used in leave-on cosmetics at a dosage of no more than 89%, methylpropanediol is safe when used in leave-on cosmetics at a dosage of no more than 21.2%, PEG-40 hydrogenated castor oil is safe when used in leave-on cosmetics at a dosage of no more than 22%, and ethylhexylglycerin is safe when used in leave-on cosmetics at a dosage of no more than 2%. , caprylhydroxamic acid is safe when used in leave-on cosmetics at a dosage not exceeding 0.25%, budding pullulan polysaccharide is safe when used in leave-on cosmetics at a dosage not exceeding 12%, parahydroxyacetophenone is safe when used in leave-on cosmetics at a dosage not exceeding 5%, biosaccharide gum-1 is safe when used in leave-on cosmetics at a dosage not exceeding 6%, sodium hyaluronate is safe when used in leave-on cosmetics at a dosage not exceeding 2%, carbomer is safe when used in leave-on cosmetics at a dosage not exceeding 15%, polysorbate-20 is safe when used in leave-on cosmetics at a dosage not exceeding 9.1%, caprylyl glycol is safe when used in leave-on cosmetics at a dosage not exceeding 5%, and xanthan gum is safe when used in leave-on cosmetics at a dosage not exceeding 6%. The total amount of these components added in this formula is not higher than the amount determined by the CIR evaluation results and can be used safely.

[0104] The anti-wrinkle essence water in this embodiment is a stay-on cosmetic. When using it, after cleansing, close your eyes, spray it evenly on the entire face at a distance of about 20 cm from the face, and wait for the face to absorb it or pat it with both hands to help the face absorb it. The default daily average usage for an adult weighing 60 kg is 0.72 g.

[0105] The anti-wrinkle essence water mainly has the effects of anti-wrinkle and skin care, among which the anti-wrinkle mechanism is as follows: the combination of different components in the anti-wrinkle essence water enables it to promote skin metabolism, anti-oxidation, and reduce inflammation. It promotes the synthesis of collagen by enhancing metabolism and promoting cell regeneration, thereby improving skin sagging and wrinkles, enhancing skin firmness, and achieving anti-aging effects. It reduces the formation of fine lines and wrinkles by neutralizing free radicals through anti-oxidation, reduces skin inflammation through anti-inflammatory, regulates skin microecology, slows down skin aging, and reduces the formation of wrinkles.

[0106] Example 2: An anti-wrinkle essence water

[0107] The anti-wrinkle essence water is composed of the following materials in parts by weight: 96.6368 parts of water; 1.0025 parts of 1,2-pentanediol; 0.525 parts of glucuronic acid; 0.338 parts of propylene glycol; 0.2925 parts of 1,3-propanediol; 0.28 parts of mannose; 0.1967 parts of 1,2-hexanediol; 0.169 parts of butylene glycol; 0.13 parts of methylpropanediol; 0.105 parts of beta-glucan; 0.07 parts of lactobionic acid; 0.05 parts of sodium citrate; 0.0375 parts of PEG-40 hydrogenated castor oil; 0.0241 parts of ethylhexylglycerol; 0.0225 parts of caprylhydroxamic acid; 0.02 parts of budding short pedunculate polysaccharide; 0.0175 parts of p-hydroxyacetophenone; phenoxyethanol 0.0159 parts; 0.014 parts of o-cymene-5-ol; 0.011 parts of biosaccharide gum-1; 0.01005 parts of citric acid; 0.01 parts of glycerophosphoinositol choline salt; 0.006 parts of European thyme extract; 0.00375 parts of clove bud extract; 0.00375 parts of mountain pepper fruit oil; 0.0025 parts of eye-shaped veins microalgae extract; 0.002 parts of sodium hyaluronate; 0.0016 parts of carbomer; 0.001 parts of polysorbate-20; 0.00066 parts of caprylyl glycol; 0.00045 parts of Sophora flavescens root extract; 0.00012 parts of xanthan gum; 0.00009 parts of fullerene; 0.00002 parts of palmitoyl tripeptide-1 / palmitoyl hexapeptide-12; 0.00001 parts of palmitoyl tetrapeptide-7. Here, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 is a mixture of the two, each of which is 0.00001 parts. The acquisition and preparation methods of various substances in the anti-wrinkle essence water in this embodiment can refer to Example 1, and will not be repeated here.

[0108] Example 3: Anti-wrinkle essence water

[0109] The anti-wrinkle essence water is composed of the following materials in parts by weight: 106.3005 parts of water; 1.1028 parts of 1,2-pentanediol; 0.5775 parts of glucuronic acid; 0.3718 parts of propylene glycol; 0.3218 parts of 1,3-propanediol; 0.31 parts of mannose; 0.2164 parts of 1,2-hexanediol; 0.186 parts of butylene glycol; 0.143 parts of methyl propanediol; 0.1155 parts of beta-glucan; Sugar acid 0.077 parts; sodium citrate 0.045-0.055 parts; PEG-40 hydrogenated castor oil 0.0413 parts; ethylhexylglycerol 0.0265 parts; caprylhydroxamic acid 0.0203-0.0248 parts; budding short pedunculate polysaccharide 0.022 parts; p-hydroxyacetophenone 0.0193 parts; phenoxyethanol 0.0175 parts; o-cymene-5-ol 0.0154 parts; biosaccharide gum-1 0.0121 parts; citric acid 0.011055 parts; glycerophosphoinositol choline salt 0.011 parts; thyme extract 0.0066 parts; clove bud extract 0.004125 parts; mountain pepper fruit oil 0.004125 parts; eye-shaped veins of microcystis extract 0.00275 parts; sodium hyaluronate 0.0022 parts; carbomer 0.00176 parts; polysorbate-20 0.0011 parts; caprylyl glycol 0.000726 parts; sophora flavescens root extract 0.000495 parts; xanthan gum 0.000132 parts; fullerene 0.000099 parts; palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 0.000022 parts; palmitoyl tetrapeptide-7 0.000011 parts. Here, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 is a mixture of the two, each of which is 0.000011 parts. The acquisition and preparation methods of various substances in the anti-wrinkle essence water in this embodiment can refer to Example 1, and will not be repeated here.

[0110] Safety Assessment of Anti-Wrinkle Essence Water

[0111] In order to test the safety of the relevant components of the anti-wrinkle essence water, in accordance with the requirements of the "Technical Guidelines for Cosmetic Safety Assessment" and based on the current level of scientific knowledge, Guangdong Wande Testing Technology Co., Ltd. was commissioned to evaluate the risk substances that may be introduced by cosmetic raw materials, generated or introduced during the production process. The safety risk substances that may exist in the product are impurities that cannot be avoided technically and are introduced by the raw materials.

[0112] The following test results are based on the anti-wrinkle essence water in Example 2 above.

[0113] Among them, water, 1,2-pentanediol, mannose, 1,2-hexanediol, butylene glycol, β-glucan, ethylhexylglycerin, caprylhydroxamic acid, budding pullulan, biosaccharide gum, glycerophosphoinositol choline salt, sodium hyaluronate, caprylyl glycol, xanthan gum, fullerene, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12, and palmitoyl tetrapeptide-7 do not contain any risky substances and have been identified as safe for use in this anti-wrinkle essence water.

[0114] The amount of glucuronic acid used complies with the provisions of the "Cosmetic Safety Technical Specifications" (2015 Edition) on restricted ingredients in cosmetics (Table 3). The total amount of this type of raw material is ≤6% (in acid terms), and the product pH is ≥3.5 (except for rinse-off hair products), which is safe to use.

[0115] The amount of lactobionic acid used is in compliance with the provisions of the "Cosmetic Safety Technical Specifications" (2015 Edition) on restricted ingredients in cosmetics (Table 3). The total amount of this type of raw material is ≤6% (in acid terms), and the product pH is ≥3.5 (except for rinse-off hair products), which is safe to use.

[0116] The amount of sodium citrate used complies with the provisions of the Cosmetic Safety Technical Specifications (2015 Edition) for restricted ingredients in cosmetics (Table 3) No. 37. The total amount of this type of raw material is ≤6% (in acid terms), and the product pH is ≥3.5 (except for rinse-off hair products), which can be used safely.

[0117] The dosage of o-cymene-5-ol complies with the provisions of No. 33 of the "Technical Specifications for Safety of Cosmetics" (2015 edition) for permitted preservatives in cosmetics (Table 4). This ingredient does not pose a safety risk and will not cause potential harm to human health.

[0118] The amount of citric acid used complies with the provisions of the Cosmetic Safety Technical Specifications (2015 Edition) Cosmetic Restricted Components (Table 3) No. 37. The total amount of this type of raw material is ≤6% (in acid terms), and the product pH is ≥3.5 (except for rinse-off hair products), which can be used safely.

[0119] Propylene glycol, 1,3-propanediol, methyl propanediol, PEG-40 hydrogenated castor oil, polysorbate-20, these components have potential diethylene glycol risks. The EU began to implement the "EU Cosmetics Regulation 1223 / 2009 / EC" on July 11, 2013. In this regulation, diethylene glycol is prohibited from being used as a raw material in cosmetics, and it is stipulated that the content of diethylene glycol as an impurity in the raw material in the final cosmetic product should be ≤0.1%. After evaluation, the content of diethylene glycol brought in by this ingredient meets the safety requirements, so this product is safe. See the inspection report of this product in the table below for details.

[0120] PEG-40 hydrogenated castor oil, phenoxyethanol, polysorbate-20, these components have potential dioxin risks. The dioxin test results of this product meet the regulatory requirements. The dioxin residue meets the requirements of the "Cosmetic Safety Technical Specifications" (2015 Edition) that the dioxin limit value in cosmetics should not exceed 30mg / kg. Please see the inspection report of this product in the table below for details.

[0121] Parahydroxyacetophenone and phenoxyethanol have potential phenol risks. According to the Japanese cosmetic standards, the limit of phenol in cosmetics is 0.1g / 100g. According to the information provided by the supplier, the phenol content of this raw material is ≤10mg / kg. After calculation, the phenol content brought in is far less than the limit in cosmetics. Therefore, these raw materials do not have safety risks and will not cause potential harm to human health. The test also shows that the anti-wrinkle essence water does not contain this harmful substance. Please see the test report of this product in the table below for details.

[0122] Carbomer does not contain any risky substances. In particular, benzene is not used in any link of the production process of the raw material of this ingredient, and there will be no benzene residue under foreseeable circumstances, so it is believed that this ingredient will not cause potential harm to human health.

[0123] The risk substances that may be contained in the components of European thyme extract, clove bud extract, mountain pepper fruit oil, eye-shaped veins of Nannochloropsis extract, and Sophora flavescens root extract are pesticide residues. According to the "Guidelines for Risk Assessment of Safety Risk Substances Possible in Cosmetics" (Guidelines for Risk Assessment of Safety Risk Substances Possible in Cosmetics) (National Food and Drug Administration Permit

[2010] No. 339), Article 5, Item 7, requires the declaration of pesticide residues. These raw materials are not used directly after mechanical processing, but are pressed, extracted, precipitated, etc. As non-pure crude processed raw materials, there is no risk of pesticide residues. As far as this product is concerned, there are no safety risk substances. Please see the inspection report in the table below for details.

[0124] Table 1 below is the test report on harmful bacteria, heavy metals and dioxane content in the product.

[0125] Table 1 - Inspection report of harmful bacteria, heavy metals and dioxane content 3. Hygiene indicators

[0126]

[0127] As can be seen from Table 1, the test results of the harmful bacteria, heavy metals and dioxane content in the anti-wrinkle essence water meet the requirements of the "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0128] Table 2 below is the test report of diethylene glycol and phenol content in the product.

[0129] Table 2 - Test report of diethylene glycol and phenol content

[0130]

[0131] Note 1. “Not detected” is lower than the detection concentration of the method.

[0132] It can be seen from Table 2 that the test results of diethylene glycol and phenol in the anti-wrinkle essence water meet the requirements of the "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0133] Table 3 below is the inspection report on the pesticide residue content in the product.

[0134] Table 3- Inspection report of pesticide residues

[0135]

[0136] Note 1. “Not detected” = less than the detection concentration of the method.

[0137] It can be seen from Table 3 that the test results of the relevant test items of pesticide residues in the anti-wrinkle essence water meet the requirements of the "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0138] Table 4 below shows the test results of sensory indicators and physicochemical indicators.

[0139] Table 4 - Sensory index and physical and chemical index test Table 1. Sensory index

[0140]

[0141] 2. Influence indicators

[0142]

[0143] As shown in Table 4, the sensory indicators and physical and chemical indicators of the anti-wrinkle essence water, including appearance, aroma, heat resistance, cold resistance and pH index, all meet the requirements.

[0144] The safety assessment results of the above anti-wrinkle essence water show that all ingredients will not cause harm to human health at the concentration of this product; the detection and assessment results of possible safety risk substances show that they will not cause harm to human health; the microbiological test results show that the microorganisms of this product meet the relevant requirements of the "Technical Specifications for Safety of Cosmetics" (2015 edition); the harmful substance test results show that the harmful substance content of this product meets the relevant requirements of the "Technical Specifications for Safety of Cosmetics" (2015 edition); no harmful interactions are foreseen between the ingredients in the formula. In summary, it is believed that this product will not cause harm to human health under normal, reasonable and foreseeable conditions of use.

[0145] It can be seen from the above embodiments that the anti-wrinkle essence water is a leave-on cosmetic that can be sprayed on the face and used every day. According to the relevant provisions of the "Technical Guidelines for Cosmetic Safety Assessment (2021 Edition)", the water, 1,2-pentanediol, glucuronic acid, propylene glycol, 1,3-propanediol, mannose, 1,2-hexanediol, butylene glycol, methylpropanediol, β-glucan, lactobionic acid, sodium citrate, PEG-40 hydrogenated castor oil, ethylhexylglycerol, caprylylhydroxamic acid, budding short pedunculate polysaccharide, para-hydroxyacetophenone, phenoxyethanol, o-cymene-5-ol, biosaccharide gum-1, citric acid, glycerophosphoinositol choline salt, Thymus serpyllum extract, Litsea cubeba extract A) 35 ingredients were evaluated, including fruit oil, Eugenia Caryophyllus flower bud extract, Nannochloropsis octahedralis extract, sodium hyaluronate, carbomer, polysorbate-20, caprylyl glycol, Sophora flavescens root extract, xanthan gum, fullerene, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12, and palmitoyl tetrapeptide-7. The harmful substances and microorganisms of the products were tested, and the possible presence of pesticide residues, diethylene glycol, dioxane, phenol and other 4 risk substances were evaluated. The results showed that the product would not cause harm to human health under normal, reasonable and foreseeable use.

[0146] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0147] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An anti-wrinkle essence water, characterized in that: The anti-wrinkle essence water is composed of the following materials in parts by weight: Water 86.9731-106.3005 parts; 0.9023 to 1.1028 parts of 1,2-pentanediol; Glucuronic acid 0.4725-0.5775 parts; Propylene glycol 0.3042-0.3718 parts; 1,3-propylene glycol 0.2633-0.3218 parts; Mannose 0.25-0.31 parts; 1,2-hexanediol 0.1771-0.2164 parts; 0.152-0.186 parts of butanediol; Methylpropanediol 0.117-0.143 parts; β-glucan 0.0945-0.1155 parts; Lactobionic acid 0.063-0.077 parts; 0.045-0.055 parts of sodium citrate; PEG-40 hydrogenated castor oil 0.0338-0.0413 parts; Ethylhexylglycerin 0.0217-0.0265 parts; 0.0203-0.0248 parts of octanoylhydroxamic acid; 0.018-0.022 parts of budding short-stalked enzyme polysaccharide; 0.0158 to 0.0193 parts of p-hydroxyacetophenone; Phenoxyethanol 0.0143-0.0175 parts; 0.0126-0.0154 parts of o-cymene-5-ol; Biosaccharide gum-1 0.0099~0.0121 parts; 0.009045 to 0.011055 parts of citric acid; 0.009-0.011 parts of glycerophosphoinositol choline salt; 0.0054-0.0066 parts of thyme extract; 0.003375-0.004125 parts of clove bud extract; 0.003375-0.004125 parts of Litsea cubeba fruit oil; 0.00225-0.00275 parts of Nannochloropsis oculata extract; Sodium hyaluronate 0.0018-0.0022 parts; Carbomer 0.001584-0.00176 parts; Polysorbate-20 0.0009-0.0011 parts; Caprylyl glycol 0.000594 to 0.000726 parts; 0.000405-0.000495 parts of Sophora flavescens root extract; Xanthan gum 0.000108-0.000132 parts; Fullerene 0.000081 to 0.000099 parts; Palmitoyl tripeptide-1 / palmitoyl hexapeptide-12 0.000018~0.000022 parts; Palmitoyl tetrapeptide-7 0.000009~0.000011 parts.

2. The anti-wrinkle essence water according to claim 1, characterized in that: The anti-wrinkle essence water is composed of the following materials in parts by weight: Water 96.6368 parts; 1,2-pentanediol 1.0025 parts; Glucuronic acid 0.525 parts; Propylene glycol 0.338 parts; 0.2925 parts of 1,3-propylene glycol; Mannose 0.28 parts; 0.1967 parts of 1,2-hexanediol; Butanediol 0.169 parts; Methylpropanediol 0.13 parts; β-glucan 0.105 parts; Lactobionic acid 0.07 parts; 0.05 parts of sodium citrate; PEG-40 hydrogenated castor oil 0.0375 parts; Ethylhexylglycerin 0.0241 parts; 0.0225 parts of octanoylhydroxamic acid; 0.02 parts of budding short-stalked enzyme polysaccharide; 0.0175 parts of p-hydroxyacetophenone; Phenoxyethanol 0.0159 parts; 0.014 parts of o-cymene-5-ol; Biosaccharide Gum-1 0.011 parts; 0.01005 parts of citric acid; 0.01 part of glycerophosphoinositol choline salt; 0.006 parts of thyme extract; 0.00375 parts of clove bud extract; 0.00375 parts of Litsea cubeba fruit oil; 0.0025 parts of Nannochloropsis oculata extract; 0.002 parts of sodium hyaluronate; Carbomer 0.0016 parts; Polysorbate-20 0.001 parts; Caprylyl glycol 0.00066 parts; Sophora flavescens root extract 0.00045 parts; Xanthan gum 0.00012 parts; Fullerene 0.00009 parts; Palmitoyl Tripeptide-1 / Palmitoyl Hexapeptide-12 0.00002 parts; Palmitoyl Tetrapeptide-7 0.00001 parts.

3. The anti-wrinkle essence water according to claim 2, characterized in that: The European thyme extract is an extract obtained by squeezing and extracting the European thyme plant; The clove bud extract is an extract obtained by squeezing and extracting clove buds; The Nannochloropsis oculata extract is an extract obtained by squeezing and extracting Nannochloropsis oculata; The Sophora flavescens root extract is an extract obtained by squeezing and extracting the Sophora flavescens root.

4. The anti-wrinkle essence water according to claim 3, characterized in that: The extraction method of the thyme extract, the clove bud extract, the Nannochloropsis oculiformis extract and the Sophora flavescens root extract is carbon dioxide supercritical extraction.

5. The method for preparing the anti-wrinkle essence water according to claim 1 or 2, characterized in that: include: Prepare various weight portions of raw materials for preparing the anti-wrinkle essence water; Take the prepared glucuronic acid, mannose, β-glucan, lactobionic acid, appropriate amount of 1,2-hexanediol, p-hydroxyacetophenone and appropriate amount of water and mix them well as the first moisturizing agent; Take the prepared appropriate amount of phenoxyethanol, biosaccharide gum-1 and appropriate amount of water and mix them evenly as the first skin conditioning agent for later use; Take the prepared 1,3-propylene glycol, appropriate amount of 1,2-hexanediol and caprylhydroxamic acid and mix them evenly as a chelating agent; Take the prepared propylene glycol, an appropriate amount of ethylhexylglycerin, an appropriate amount of 1,2-hexanediol, and o-cymene-5-ol and mix them evenly as a preservative; Take the prepared PEG-40 hydrogenated castor oil, thyme extract, clove bud extract, Litsea cubeba fruit oil, appropriate amount of 1,2-hexanediol, caprylyl glycol, Sophora flavescens root extract and appropriate amount of water and mix well as the second skin conditioning agent for use; Take the prepared butanediol, xanthan gum, fullerene, an appropriate amount of methyl propanediol and an appropriate amount of water and mix them evenly as an antioxidant for later use; Take appropriate amount of prepared methylpropanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1 / palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7 and appropriate amount of water and mix well as the third skin conditioning agent for use; Take the prepared glycerophosphoinositol choline salt, an appropriate amount of phenoxyethanol, an appropriate amount of ethylhexylglycerin and an appropriate amount of water and mix them evenly as the fourth skin conditioning agent for later use; Take the prepared budding short-stalked enzyme polysaccharide, Nannochloropsis oculiformis extract, 1,2-pentanediol, appropriate amount of citric acid and appropriate amount of water and mix them evenly as the fifth skin conditioning agent for use; The first skin conditioner, chelating agent, preservative, second skin conditioner, antioxidant, third skin conditioner, fourth skin conditioner, fifth skin conditioner and other remaining raw materials are mixed and packaged to obtain the anti-wrinkle essence water.

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