Medicinal incense with efficacy of resolving dampness with aromatics and preparation method thereof

Abstract

The invention discloses medicinal incense with the effect of resolving dampness by aromatics and a preparation method of the medicinal incense. The medicinal incense comprises agastache rugosus, rhizoma atractylodis, honeysuckle, mint, chrysanthemum, houttuynia cordata and folia perillae acutae. The incense is prepared by a series of processes of incense preparation, incense arrangement, incense airing, incense collection, incense storage and the like. Safe and effective natural traditional Chinese medicine powder and natural Indonesia nanmu sticky powder are used, no chemical additive is added, and the composition is green, safe and free of toxic and side effects; indoor air peculiar smell is improved, air is purified, and people can feel relaxed and pleasant; the production process is simple, low in cost, suitable for industrial production and large-scale popularization and application, and wide in market prospect.

Description

Technical Field

[0001] The invention relates to an incense product, in particular to a medicinal incense with aromatic and dehumidifying effects and a preparation method thereof. Background Art

[0002] In recent years, environmental pollution has led to abnormal climate, bacterial and viral pollution, and the air quality has continued to deteriorate. The incidence of acute and chronic respiratory diseases has increased. Both upper and lower respiratory tract diseases can cause coughing up sputum, such as acute tracheobronchitis, bronchial asthma, pneumonia, tuberculosis, and chronic obstructive pulmonary disease. The syndrome of phlegm-heat blocking the lungs is caused by exogenous evil invading the lungs, stagnation and heat, heat damaging the lung fluid, refining the fluid into phlegm, or old phlegm, which turns into heat over time, phlegm and heat are mutually bound, blocking the lungs, and manifesting as the syndrome of heat in the lung meridian due to the failure of the lung to descend. The clinical manifestations are cough, yellow and thick sputum with large amount, chest tightness, wheezing and rough breathing, or even flaring of the nose, or phlegm in the throat, irritability, fever and thirst, or coughing up pus, blood, smelly sputum, chest pain, constipation, short and red urine, red tongue with yellow and greasy fur, and floating and slippery pulse. Exogenous pathogens combine with phlegm-heat to suppress lung qi, resulting in fever without aversion to cold, shortness of breath, cough, and yellow and thick phlegm. Phlegm-heat blocks the lungs, causing qi stagnation and obstruction, resulting in chest tightness and fullness. Phlegm-heat accumulates internally, disturbing the mind, resulting in irritability and restlessness. Phlegm-heat blocks the lung qi and causes it to flow upward, resulting in a red face and eyes that look as if they are falling out. Lung heat consumes body fluid, resulting in dry mouth and thirst. Because phlegm-heat accumulates internally, the tongue coating is yellow and greasy, and the patient does not drink much water. Because of the presence of exogenous pathogens, the pulse is floating, slippery, and rapid.

[0003] Since phlegm-heat accumulation in the lungs is a common respiratory disease, it can easily develop into a chronic disease if not treated in time, seriously affecting people's health. Therefore, it is very necessary to develop more drugs that are effective for this symptom. However, there are currently no reports on external treatment Chinese medicine compositions and their applications for the treatment of phlegm-heat accumulation in the lungs.

[0004] In view of the above-mentioned deficiencies in the prior art, the present invention provides a medicinal fragrance which not only has the effect of improving indoor odor but also can aromatize and dehumidify. Summary of the invention

[0005] The purpose of the present invention is to provide a medicinal fragrance that not only improves indoor odor but also can aromatize and dehumidify, in view of the shortcomings of the prior art. The medicinal fragrance is made of natural Chinese herbal medicine powder as an effective ingredient and is added with auxiliary materials such as plant adhesives. The medicinal fragrance is widely used in indoor environments such as bedrooms, hotels, toilets, corridors, etc.

[0006] The technical solution adopted by the present invention to solve its technical problem is: A medicinal fragrance with aromatic and dehumidifying effects, comprising Patchouli, Atractylodes, Houttuynia Cordata, Honeysuckle, Mint, Chrysanthemum and Perilla; the mass ratio of Patchouli, Atractylodes, Houttuynia Cordata, Honeysuckle, Mint, Chrysanthemum and Perilla is 10-15 parts of Patchouli, 10-15 parts of Atractylodes, 10-15 parts of Houttuynia Cordata, 10-15 parts of Honeysuckle, 2-5 parts of Mint, 2-5 parts of Chrysanthemum and 2-5 parts of Perilla.

[0007] A method for preparing a medicinal fragrance with aromatic and dehumidifying effects comprises the following steps: Step 1: Grind the Chinese herbal ingredients into powder; Patchouli, atractylodes, houttuynia, honeysuckle, mint, chrysanthemum and perilla are mixed as main ingredients, and the mass ratio of Patchouli, atractylodes, houttuynia, honeysuckle, mint, chrysanthemum and perilla is 10-15 parts of Patchouli, 10-15 parts of Atractylodes, 10-15 parts of Houttuynia, 10-15 parts of honeysuckle, 2-5 parts of mint, 2-5 parts of chrysanthemum and 2-5 parts of perilla, and the moisture content of the main ingredients is controlled below 10%; a Chinese medicine pulverizer is used to grind all the main ingredients into main ingredient powder; the temperature during the grinding process of the main ingredients is controlled below 80°C; Step 2: After the main material powder is screened through the screen at the outlet of the Chinese medicine grinder, the particle size is 80±5 mesh, and the main material powder is transferred to a high-viscosity high-speed mixer; Step 3: Add auxiliary sticky powder into a high-viscosity high-speed stirrer, the auxiliary sticky powder is a plant adhesive, the plant adhesive is 25-54 parts; the main material powder and the auxiliary sticky powder constitute the total powder, add water into the high-viscosity high-speed stirrer, the water is 20-40 parts; turn on the high-viscosity high-speed stirrer, stir regularly for 30 minutes, control the temperature of the total powder below 80°C during the stirring process, and stir until the adhesion is complete to form a gelatinous material; Step 4: introducing the colloid into a twin-screw extruder to form a primary incense stick of a fixed diameter at the extrusion port of the twin-screw extruder; placing the primary incense stick in a cool and dry place for standby use; Step 5: Make incense sticks with an incense making machine, adjust the thickness of the incense sticks to 2mm, cut them into 30cm lengths, place them on a sieve plate, and sort the incense; place the sorted incense in a cool and dry place to dry, control the ambient temperature at 20±5℃, and the humidity at 40%-60%, and dry them to 8.0%-10.0% moisture; collect the dried incense products, obtain the finished craft incense, and store them in a cool and dry place in a sealed manner.

[0008] The present invention also has the following additional technical features: As a further specific optimization of the technical solution of the present invention: it also includes an auxiliary material plant adhesive, the auxiliary material plant adhesive adopts a plant adhesive without artificial synthetic components, and the solvent of the plant adhesive is water.

[0009] As a further specific optimization of the technical solution of the present invention: Patchouli, Atractylodes, Houttuynia cordata, Honeysuckle, Mint, Chrysanthemum and Perilla are crushed by a traditional Chinese medicine grinder, and the discharge port of the grinder is connected with a screen.

[0010] As a further specific optimization of the technical solution of the present invention: Patchouli, Atractylodes, Houttuynia cordata, Honeysuckle, Mint, Chrysanthemum and Perilla are stirred and mixed by a high-viscosity high-speed stirrer, and the stirrer is provided with a timer switch.

[0011] As a further specific optimization of the technical solution of the present invention: the colloidal materials of Patchouli, Atractylodes, Houttuynia Cordata, Honeysuckle, Mint, Chrysanthemum and Perilla are extruded through a twin-screw extruder, and the extrusion port of the extruder is provided with different fragrance types of sanitary incense, which include stick incense, coil incense or craft incense; the fragrance types include coil incense medicinal fragrance type, stick incense medicinal fragrance type or craft incense fragrance type.

[0012] As a further specific optimization of the technical solution of the present invention: the aromatherapy and dehumidification effect is to measure the lung index through animal experiments, perform H&E staining and PAS staining on lung tissue, and detect the IL6, IL-1β and TNF-a cytokine content through Elisa kits.

[0013] Compared with the prior art, the present invention has the following advantages: The aromatic dehumidifying medicinal fragrance provided by the invention has a scientific ratio, is easy to use, and can relieve phlegm-heat symptoms.

[0014] The raw materials are easily available, natural and green, non-toxic and non-toxic, and safe to use.

[0015] Improve the odor of indoor air, purify the air, soothe people's spirit and promote blood circulation. "Shennong's Herbal Classics Hundred Records" records: "Fragrance is the righteousness of qi. When the righteousness is strong, it can naturally remove evil and ward off filth." "Compendium of Materia Medica" says: "The fragrance of Suhe can penetrate all the orifices and internal organs, so its function is to ward off all unrighteous qi." When the aromatic molecules float in the air and enter the human body through the respiratory system, they can clean the respiratory organs, enhance the respiratory function of the lungs, enhance the function of the immune system, fight against bacteria, and prevent or alleviate the symptoms of colds. "Nanjing" says: "The heart governs smell, and makes the nose know fragrance and odor." The heart governs the mind. Aromatherapy can achieve the effects of opening the orifices, awakening the brain, improving intelligence, calming the nerves and calming the nerves by regulating the mind. "Jingyue Complete Book" says: "Fragrant fragrance makes the qi and blood circulate." Therefore, Chinese medicine aromatherapy has the effect of dredging the meridians and enhancing the circulation of qi and blood.

[0016] The production process is simple and the cost is low. It is suitable for industrial production and large-scale promotion and application, and has broad market prospects. It is made by traditional sanitary incense production process. Chinese herbal spices with obvious disinfection and sterilization effects, wide sources of medicine, and high safety are selected as raw materials. Among them, Chinese herbal powder has antibacterial, insecticidal, and fungicidal effects, which can help soothe nervous tension and anxiety, especially for patients with cold precursors or colds. It has a more obvious regulatory effect on the respiratory tract, has cough and phlegm properties, can improve bronchitis, cough and runny nose, relieve symptoms, and soothe the spirit. It also has a high-efficiency killing effect on a variety of influenza viruses such as H1N1 influenza virus, thereby preventing respiratory diseases such as colds caused by influenza viruses, and playing a preventive effect. Compared with the current method of using drugs and conventional prevention and treatment of colds, the mode of action is more humane, more scientific, and more advanced. This product is natural and green, non-toxic and side-effect-free. It not only has the effect of traditional sanitary incense to improve indoor air odor, but also has the effect of inhibiting and killing germs, influenza viruses, purifying air, and preventing colds, which makes people feel relaxed and happy. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 The present invention is a flow chart of the preparation of medicinal fragrance; Figure 2 Graph showing lung index of each group of mice in the present invention; Figure 3 This is the H&E staining (40×) image of the present invention; Figure 4 This is a PAS staining (40×) image of the present invention; Figure 5 This is a comparison chart of cytokine levels in lung tissues of various groups of the present invention; Figure 6 This is a comparison chart of cytokine levels in lung tissues of various groups of the present invention; Figure 7 This is a comparison chart of cytokine levels in lung tissues of various groups of the present invention. DETAILED DESCRIPTION

[0018] Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. Example 1

[0019] A medicinal fragrance with aromatic and dehumidifying effects comprises a mixture of patchouli, atractylodes, houttuynia cordata, honeysuckle, mint, chrysanthemum and perilla as main ingredients, wherein the mass proportions of patchouli, atractylodes, houttuynia cordata, honeysuckle, mint, chrysanthemum and perilla are: 10-15 parts of patchouli, 10-15 parts of atractylodes, 10-15 parts of houttuynia cordata, 10-15 parts of honeysuckle, 2-5 parts of mint, 2-5 parts of chrysanthemum and 2-5 parts of perilla.

[0020] The medicinal incense also includes an auxiliary material plant adhesive, which is a plant adhesive without artificial synthetic components, and the solvent of the plant adhesive is water. By adding the plant adhesive, the components of the invention can be made into various forms of medicinal incense, such as thread incense, coil incense, craft incense, essential oil and other forms. The series of incense products have been proved by experiments to meet the requirements of industry regulations, and not only have the effect of improving indoor air odor like traditional sanitary incense, but also can effectively inhibit the replication of influenza virus in organisms.

[0021] The efficacy of the medicinal fragrance component of the present invention is described as follows: Patchouli, pungent, slightly warm. Enters the lung, spleen, and stomach meridians. Harmonizes the middle, dispels filth, and removes dampness. Treats colds, summer heat, cold and heat, headaches, chest and abdominal distension, vomiting, and diarrhea.

[0022] Atractylodes, pungent, bitter, warm. It enters the twelve meridians. It strengthens the spleen, dries dampness, relieves depression, and eliminates filth. It treats dampness that blocks the spleen, fatigue and sleepiness, abdominal distension, loss of appetite, vomiting and diarrhea.

[0023] Houttuynia cordata, pungent, cold. Entries into 12 meridians. Clears away heat and detoxifies, promotes diuresis and reduces swelling. Treats pneumonia and lung abscess.

[0024] Honeysuckle, sweet, cold. Enter the lung, heart, and stomach meridians. Clear away heat and detoxify, cool and dissipate wind-heat. Used for carbuncle, furuncle, throat paralysis, erysipelas, heat-toxic bloody diarrhea, wind-heat cold, and fever due to febrile diseases.

[0025] Peppermint, pungent, cool. Enters the lung and liver meridians. Disperses wind-heat. Clears the head and eyes, and clears rashes. Used for wind-heat colds, initial onset of wind-heat, headaches, red eyes, sore throat, and chest and flank distension.

[0026] Chrysanthemum, sweet and bitter, cool. Enter the lung and liver meridians. Dispel wind, clear heat, improve eyesight, detoxify. Treat headache, dizziness, red eyes, heart and chest heat.

[0027] Perilla leaf, pungent, warm. Entire twelve meridians. Release the exterior, dispel cold, regulate qi, and harmonize the circulation. Treat colds, aversion to cold, fever, cough, asthma, chest and abdominal distension.

[0028] The compatibility relationship of the medicinal fragrance components of the present invention is described as follows: The present invention mainly treats the syndrome of phlegm-heat accumulation in the lung. Efficacy: aromatic dehumidification, lung clearing and phlegm elimination, asthma and dampness elimination. Explanation of the prescription: Patchouli in the prescription can dispel filth and harmonize the middle, and Atractylodes macrocephala can dry out dampness and strengthen the spleen, and the two are the main medicines, "the spleen is the source of phlegm, and the lung is the container of phlegm". Houttuynia cordata is a bitter and cold product, which can purge fire and cool blood, and can clear the heat and toxicity in the blood; "Suwen Zhizhen Yaoda Lun" says "heat is cold", honeysuckle, chrysanthemum, and mint are sweet and cold in nature, lightly spread and disperse, penetrate heat to the surface, match with Houttuynia cordata, complement each other, enhance the effect of clearing heat and detoxification, and directly break the fire of ice cold, and are the minister medicines; Perilla leaf dispels wind and regulates qi, and is the adjuvant medicine, "Zunsheng Bajian" says: "extraordinary fragrance, burn it to help clear qi." Therefore, the fragrance can wake up the spleen and appetite, raise the clear and lower the turbid, and regulate the spleen and stomach functions to resolve phlegm. The whole formula has the main and subordinate ingredients in order, clears away dryness appropriately, dredges the blood vessels, moisturizes without being greasy, and does not damage the body fluids. Example 2

[0029] A method for preparing a medicinal fragrance with aromatic and dehumidifying effects, characterized in that it comprises the following steps: Step 1: Grind the Chinese herbal ingredients into powder; Patchouli, atractylodes, houttuynia, honeysuckle, mint, chrysanthemum and perilla are mixed as main ingredients, and the mass ratio of Patchouli, atractylodes, houttuynia, honeysuckle, mint, chrysanthemum and perilla is 10-15 parts of Patchouli, 10-15 parts of Atractylodes, 10-15 parts of Houttuynia, 10-15 parts of honeysuckle, 2-5 parts of mint, 2-5 parts of chrysanthemum and 2-5 parts of perilla, and the moisture content of the main ingredients is controlled below 10%; a Chinese medicine pulverizer is used to grind all the main ingredients into main ingredient powder; the temperature during the grinding process of the main ingredients is controlled below 80°C; Step 2: After the main material powder is screened through the screen at the outlet of the Chinese medicine grinder, the particle size is 80±5 mesh, and the main material powder is transferred to a high-viscosity high-speed mixer; Step 3: Add auxiliary sticky powder into a high-viscosity high-speed stirrer, the auxiliary sticky powder is a plant adhesive, the plant adhesive is 25-54 parts; the main material powder and the auxiliary sticky powder constitute the total powder, add water into the high-viscosity high-speed stirrer, the water is 20-40 parts; turn on the high-viscosity high-speed stirrer, stir regularly for 30 minutes, control the temperature of the total powder below 80°C during the stirring process, and stir until the adhesion is complete to form a gelatinous material; Step 4: introducing the colloid into a twin-screw extruder to form a primary incense stick of a fixed diameter at the extrusion port of the twin-screw extruder; placing the primary incense stick in a cool and dry place for standby use; Step 5: Make incense sticks with an incense making machine, adjust the thickness of the incense sticks to 2mm, cut them into 30cm lengths, place them on a sieve plate, and sort the incense; place the sorted incense in a cool and dry place to dry, control the ambient temperature at 20±5℃, and the humidity at 40%-60%, and dry them to 8.0%-10.0% moisture; collect the dried incense products, obtain the finished craft incense, and store them in a cool and dry place in a sealed manner.

[0030] Optimized: Patchouli, Atractylodes, Houttuynia cordata, Honeysuckle, Mint, Chrysanthemum and Perilla are crushed by a traditional Chinese medicine crusher, and the discharge port of the crusher is connected with a screen.

[0031] Optimized: Patchouli, Atractylodes, Houttuynia cordata, Honeysuckle, Mint, Chrysanthemum and Perilla are stirred and mixed with a high-viscosity high-speed stirrer, and the stirrer is equipped with a timer switch.

[0032] Optimized: The colloidal materials of Patchouli, Atractylodes, Houttuynia Cordata, Honeysuckle, Mint, Chrysanthemum and Perilla are extruded through a twin-screw extruder, and the extrusion port of the extruder is provided with different scents of sanitary incense, including stick incense, coil incense or craft incense; the scents include coil incense medicinal fragrance type or stick incense medicinal fragrance type or craft incense fragrance type. Example 3

[0033] A medicinal incense with aromatherapy and dehumidification effects, and application of the medicinal incense in aromatherapy and dehumidification and antiviral.

[0034] The aromatherapy and dehumidification effect was evaluated by measuring the lung index through animal experiments, performing H&E staining and PAS staining on lung tissue, and detecting the IL6, IL-1β and TNF-a cytokine contents using Elisa kits. Example 4

[0035] A medicinal fragrance with antiviral efficacy, and application of the medicinal fragrance in preparing aromatic, dehumidifying and antiviral products.

[0036] The aromatherapy and dehumidification effect was evaluated by measuring the lung index through animal experiments, performing H&E staining and PAS staining on lung tissue, and detecting the IL6, IL-1β and TNF-a cytokine contents using Elisa kits. Example 5

[0037] The present invention is based on a convenient and humanized hygienic incense, utilizes my country's rich Chinese herbal medicine resources, and scientifically formulates and compates to develop an anti-cold medicinal incense for preventing common colds, influenza and other respiratory diseases. For a better understanding of the present invention, the composition of the anti-cold medicinal incense and its therapeutic effect on influenza-infected mice are described below through specific embodiments and experiments. The raw materials involved, unless otherwise specified, can all be obtained from commercial channels, and the experimental methods and operating methods involved, unless otherwise specified, are all conventional means.

[0038] Firstly, cedar powder and Chinese herbal medicines (Agastache rugosa, Atractylodes macrocephala, Houttuynia cordata, Honeysuckle, Mint, Chrysanthemum, Perilla frutescens) with obvious disinfection and bactericidal effects, wide sources and safe use were screened, and anti-infection medicinal incense was made using traditional incense making technology. The composition and ratio of Chinese herbal medicines were screened, and the single-component and multi-component combination effect tests were investigated. Some representative data are shown in Table 1 below.

[0039] Table 1 The content of active ingredients in different formulas of medicinal fragrances

[0040] The exemplary data show that Patchouli, Atractylodes, Houttuynia Cordata, Honeysuckle, Mint, Chrysanthemum, and Perilla all have certain antiviral effects. However, when used together, they obviously promote each other and coordinate to enhance the bactericidal and antiviral effects. Among them, the Chinese herbal medicine ingredients reach more than 75%, and the antiviral effect is the strongest. The experiment proves that the formula of the medicinal fragrance provided by the present invention is scientific and reasonable, and has significant effects of clearing heat and resolving phlegm and antiviral. Example 6

[0041] Animal experiments 1. Experimental Materials 1.1 Animals Thirty C57BL / 6J mice, weighing (18-22) g, half male and half female, were purchased from Beijing Weitonglihua Experimental Animal Co., Ltd.

[0042] 1.2 Drugs The medicine of the Chinese medicine composition 1 of the present invention: reference formula 1.

[0043] The medicine of the second Chinese medicine composition of the present invention: reference formula 2.

[0044] 1.3 Main Reagents IL-6, IL-1β, TNF-α ELISA kits (Wuhan Cloud-Clone Technology Co., Ltd., catalog number SEA079Mu, SEA563Mu, SEA133Mu).

[0045] 2. Modeling and treatment methods 2.1 Animal grouping and modeling Twenty-four mice were divided into four groups according to their body weight, namely, blank group, model group, formula 1 group, and formula 2 group, with 6 mice in each group. The mice were placed in a small animal anesthesia machine and lightly anesthetized with isoflurane. Except for the blank group, the other groups were given 2 times the half lethal dose (LD50) of PR8 virus drops to prepare IAV infection mouse models, 50 μL per mouse, and a total of 1 intranasal infection; the blank group mice were given 50 μL of PBS drops to the nose.

[0046] 2.3 Construction of the olfactory device The mouse olfactory device is mainly composed of three parts: a mouse incubator, an aromatherapy machine, and a test chamber controller. The incubator is a transparent glass box of 80cm×50cm×70cm, and the interior is divided into two layers by a breathable glass plate. There are multiple small ventilation holes on the upper sides of the box that can be opened or closed at will to maintain the stability of the concentration of volatile substances in the box. The aromatherapy machine is responsible for accurately controlling the release rate and ignition temperature of the volatile oil of the incense stick. The controller is connected to the circulating fan, which quickly promotes the air circulation in the box with the help of the efficient operation of the fan, so as to achieve rapid and uniform distribution of gas. This olfactory device adopts a semi-enclosed design with internal gas circulation and adjustable external ventilation volume, combined with the precise control function of the aromatherapy machine, to create an experimental environment with relatively stable odor concentration.

[0047] 2.4 Sniffing method First, the whole set of sniffing device was placed in an air-conditioned room at 23-25℃, and the aromatherapy machine (release rate of 100µL / h) in working state was placed in the incubator; the mice in the formula 1 group and the formula 2 group were placed in the incubator to sniff the incense sticks. Sniffing was done twice a day, 1h / time, for 4 days. The mice in the blank group and the model group were also placed in the incubator during the same period of time, but they did not sniff the incense sticks.

[0048] 3. Observation indicators and methods: 3.1 Calculation of lung index: Weigh the body weight and total lung weight of the mouse and calculate the lung index. Lung index = lung weight (g) / body weight (g) × 100%.

[0049] 3.2 Lung tissue pathology: The right middle lung lobe of mice was fixed in 4% paraformaldehyde solution for 24 h, dehydrated with gradient ethanol, embedded in paraffin, sectioned (4 μm thick), stained with hematoxylin-eosin and PAS, and the pathological changes were observed under a microscope (100×).

[0050] 3.3ELISA test: 10% lung tissue homogenate was prepared by crushing the tissue at a ratio of 1 mg tissue to 9 µL saline. Centrifuge at 3000 r / min for 10 min at 4°C and collect the supernatant for subsequent testing.

[0051] 4. Statistical Analysis Graph PadPrism9.0 software was used for statistical analysis and plotting of data, and the results were expressed as mean ± standard deviation (xˉ±s). The Shapiro-Wilk test or Smirnov-Kolmogorov test was used to determine whether the data obeyed or approximated normal distribution. Two-way analysis of variance was used for comparison among multiple groups, and Tukey test was used for comparison between two groups. The difference was statistically significant when P<0.05.

[0052] 5. Results 5.1 Lung Index Figure 2 The figure is a schematic diagram of the lung index of mice in each group. The values ​​are expressed as mean±S, ***P<0.001, ****P<0.0001. Compared with the normal group, the lung index of mice in the model group was significantly increased (P<0.0001). The lung index of mice treated with formula 1 and formula 2 decreased to varying degrees. Compared with the model group, the lung index of mice in formula 1 and formula 2 groups decreased significantly (P<0.001).

[0053] 5.2 Lung tissue pathology The results showed that in the normal group, the lung tissue structure was relatively clear, the alveolar structure was intact as a whole, the blood vessels were round under the microscope, inflammatory cell infiltration was occasionally seen, the alveolar interstitium was basically normal, and the alveolar size was basically the same. In the model group, the lung tissue structure was relatively fuzzy under the microscope, inflammatory cell infiltration was seen around most blood vessels, and inflammatory cell infiltration was also seen around most bronchi and bronchioles. Intermittent annular or crescent-shaped annular infiltration was seen in the trachea, and diffuse inflammatory cells were also seen in the lung tissue interstitium. The inflammatory infiltration foci were enlarged and even connected and fused to each other. Fibroblasts proliferated severely, and the local alveolar cavity basically disappeared. After treatment, the inflammatory cell infiltration and the degree of bronchial lumen stenosis were reduced to varying degrees in the formula 1 group and the formula 2 group, such as Figure 3 Schematic diagram of H&E staining (40×), such as Figure 4 Schematic diagram of PAS staining (40×).

[0054] 5.3ELISA detection of cytokine content in lung tissue of each group Figure 5-Figure 7 The figure is a comparison of cytokine levels in lung tissues of each group. The values ​​are expressed as mean±S, ****P<0.0001. Compared with the blank group, the levels of IL-6, IL-1β, and TNF-α in lung tissues of the model group were significantly increased (P<0.05). Compared with the model group, the levels of IL-6, IL-1β, and TNF-α in lung tissues of the formula 1 group and the formula 2 group were significantly decreased (P<0.05).

[0055] The results show that the medicinal incense prepared by the present invention has the functions of clearing away heat and reducing phlegm and antiviral, and has a killing effect on influenza viruses in organisms. The Chinese herbal medicine component reaches more than 75%, and the antiviral effect is the strongest. For a variety of pathogens, as the content of Chinese herbal medicine increases, the effect becomes more obvious. By burning incense indoors, bacteria and viruses in indoor air can be efficiently inhibited and killed, even influenza viruses, etc., which greatly improves the indoor air quality and can effectively prevent the spread of colds, influenza, etc. The product can have a huge application space in the method for disinfecting bacteria and viruses and the preparation of products for killing bacteria and viruses, and is widely used in indoor environments such as bedrooms, hotels, hospitals, toilets, corridors, etc.

[0056] The above detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention but merely represents selected embodiments of the present invention.

Claims

1. A medicinal fragrance with aromatic and dehumidifying effects, characterized in that: The invention comprises Patchouli, Atractylodes, Honeysuckle, Mint, Chrysanthemum, Houttuynia Cordata and Perilla Leaf; the mass ratio of Patchouli, Atractylodes, Houttuynia Cordata, Honeysuckle, Mint, Chrysanthemum and Perilla Leaf is 10-15 parts of Patchouli, 10-15 parts of Atractylodes, 10-15 parts of Houttuynia Cordata, 10-15 parts of Honeysuckle, 2-5 parts of Mint, 2-5 parts of Chrysanthemum and 2-5 parts of Perilla.

2. The medicinal incense with aromatic and dehumidifying effect according to claim 1, characterized in that: The invention also comprises an auxiliary plant adhesive, wherein the auxiliary plant adhesive is a plant adhesive containing no artificial synthetic components, and the solvent of the plant adhesive is water.

3. A method for preparing a medicinal fragrance with aromatic and dehumidifying effects, characterized in that: The steps include: Step 1: Grind the Chinese herbal ingredients into powder; Patchouli, atractylodes, honeysuckle, mint, chrysanthemum, houttuynia cordata and perilla leaves are mixed as main ingredients, the mass ratio of Patchouli, atractylodes, honeysuckle, mint, chrysanthemum, houttuynia cordata and perilla leaves is 10-15:10-15:10-15:10-15:2-5:2-5:2-5, and the moisture content of the main ingredients is controlled below 10%; a traditional Chinese medicine grinder is used to grind all the main ingredients into main ingredient powder; the temperature of the main ingredients during grinding is controlled below 80°C; Step 2: After the main material powder is screened through the screen at the outlet of the Chinese medicine grinder, the particle size is 80±5 mesh, and the main material powder is transferred to a high-viscosity high-speed mixer; Step 3: Add auxiliary sticky powder into a high-viscosity high-speed stirrer, the auxiliary sticky powder is a plant adhesive, the plant adhesive is 25-54 parts; the main material powder and the auxiliary sticky powder constitute a total powder, add water into the high-viscosity high-speed stirrer, the water is 20-40 parts; turn on the high-viscosity high-speed stirrer, stir regularly for 30 minutes, control the temperature of the total powder below 80°C during stirring, and stir until the adhesion is complete to form a gelatinous material; Step 4: introducing the colloid into a twin-screw extruder to form a primary incense stick of a fixed diameter at the extrusion port of the twin-screw extruder; placing the primary incense stick in a cool and dry place for standby use; Step 5: Make incense sticks with an incense making machine, adjust the thickness of the incense sticks to 2mm, cut them into 30cm lengths, place them on a sieve plate, and sort the incense; place the sorted incense in a cool and dry place to dry, control the ambient temperature at 20±5℃, and the humidity at 40%-60%, and dry them to 8.0%-10.0% moisture; collect the dried incense products, obtain the finished craft incense, and store them in a cool and dry place in a sealed manner.

4. The medicinal incense with aromatic and dehumidifying effect according to claim 1, characterized in that: The Patchouli, Atractylodes, Honeysuckle, Mint, Chrysanthemum, Houttuynia Cordata and Perilla Leaf are pulverized by a traditional Chinese medicine pulverizer, and a screen is connected to the discharge port of the pulverizer.

5. The medicinal incense with aromatic and dehumidifying effect according to claim 1, characterized in that: The Patchouli, Atractylodes, Honeysuckle, Mint, Chrysanthemum, Houttuynia Cordata and Perilla Leaf are stirred and mixed by a high-viscosity high-speed stirrer, and the stirrer is provided with a timer switch.

6. The medicinal incense with aromatic and dehumidifying effect according to claim 1, characterized in that: The colloidal material of Patchouli, Atractylodes, Honeysuckle, Mint, Chrysanthemum, Houttuynia Cordata and Perilla Leaf is extruded through a twin-screw extruder, and the extrusion port of the extruder is provided with different fragrance types of sanitary incense, the different sanitary incense include stick incense, coil incense or craft incense; the fragrance type includes coil incense medicinal fragrance type or stick incense medicinal fragrance type or craft incense fragrance type.

7. A medicinal fragrance with aromatic and dehumidifying effects, characterized in that: The medicinal fragrance is used in aromatherapy, dehumidification and antiviral.

8. The medicinal incense with aromatherapy and dehumidification effect according to claim 1, characterized in that: The aromatherapy and dehumidification effect was evaluated by measuring the lung index through animal experiments, performing H&E staining and PAS staining on lung tissue, and detecting the IL6, IL-1β and TNF-a cytokine contents using Elisa kits.

9. A medicinal fragrance with aromatic and dehumidifying effects, characterized in that: The medicinal fragrance is used in preparing products for aromatizing, dehumidifying and antiviral.

10. The medicinal incense with aromatherapy and dehumidification effect according to claim 1, characterized in that: The aromatherapy and dehumidification effect was evaluated by measuring the lung index through animal experiments, performing H&E staining and PAS staining on lung tissue, and detecting the IL6, IL-1β and TNF-a cytokine contents using Elisa kits.

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