Traditional Chinese medicine extract for relieving cough, dredging orifices and reducing fever for children as well as preparation method and application of traditional Chinese medicine extract

Abstract

The invention discloses a traditional Chinese medicine extract for relieving cough, dredging orifices and reducing fever for children as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine extract is extracted from the following raw materials in parts by mass: 2-5 parts of cocklebur fruit, 2-5 parts of radix angelicae, 2-5 parts of pogostemon cablin, 2-5 parts of perilla leaf, 2-5 parts of folium mori, 1-3 parts of mint, 2-5 parts of honeysuckle, 1-3 parts of fructus forsythiae, 2-4 parts of fructus arctii, 1-3 parts of folium isatidis, 1-3 parts of ginger processed pinellia, 1-3 parts of immature bitter orange, 2-4 parts of platycodon grandiflorum, 2-4 parts of tussilago farfara, 2-5 parts of folium eriobotryae, 2-5 parts of gynostemma pentaphyllum and 2-5 parts of radix stemonae. The traditional Chinese medicine composition is prepared from 2-5 parts of cassia twig, 2-5 parts of radix puerariae, 1-3 parts of herba elsholtziae, 2-5 parts of rhizoma atractylodis, 1-3 parts of fructus amomi rotundus, 2-5 parts of rhizoma atractylodis macrocephalae, 2-4 parts of endothelium corneum gigeriae galli and 1-3 parts of flos caryophylli. The traditional Chinese medicine extract disclosed by the invention has an excellent curative effect in relieving cough, opening orifices and bringing down fever for children.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, and more particularly to a traditional Chinese medicine extract for relieving cough, clearing the meridians and relieving fever in children, and a preparation method and application thereof. Background Art

[0002] Cough and fever in children is a very common combination of symptoms in pediatric clinical practice, which is usually closely related to respiratory infections. Coughing is a self-protection mechanism of the body, aimed at clearing foreign matter, sputum or pathogens in the respiratory tract, while fever is a systemic response of the body to infection or inflammation, aimed at raising body temperature to inhibit the reproduction of pathogens. These symptoms are common in diseases such as colds, bronchitis, and pneumonia. Pathogens include viruses (such as influenza virus, respiratory syncytial virus), bacteria (such as Streptococcus pneumoniae, Haemophilus influenzae) and other microorganisms. Children's immune systems are not yet fully developed, so they are more vulnerable to invasion by these pathogens, leading to symptoms such as cough and fever.

[0003] According to TCM theory, children's cough and fever are mostly caused by the six exogenous pathogens (wind, cold, heat, dampness, dryness, and fire) or the seven internal emotions (joy, anger, worry, thought, sadness, fear, and shock), which lead to the failure of lung qi to be released and the internal generation of phlegm. Exogenous coughs are mainly divided into wind-cold coughs and wind-heat coughs. The former is manifested by a heavy cough, thin white phlegm, aversion to cold and fever, while the latter is manifested by a uncomfortable cough, thick yellow phlegm, fever and thirst. Internal injury coughs are mostly caused by spleen and lung weakness, phlegm and dampness in the lungs, yin deficiency and lung heat, etc., and are manifested by weak coughs, large amounts of white phlegm or dry coughs without phlegm, and afternoon hot flashes. TCM focuses on syndrome differentiation and treatment. According to the specific constitution, condition and seasonal changes of the child, it flexibly uses the treatment methods of dispelling cold, clearing heat and promoting lung function, resolving phlegm and relieving cough, nourishing yin and moistening the lungs, so as to achieve the purpose of treating both the symptoms and the root causes.

[0004] Traditional Chinese medicine for treating children's cough, based on the theory of traditional Chinese medicine, achieves individualized treatment by harmonizing yin and yang, unblocking meridians, strengthening the body and eliminating evil, etc. However, the effect of traditional Chinese medicine is directly related to the proportion and compatibility of its various drugs. Many traditional Chinese medicines for treating children's cough and fever in the prior art are often not comprehensive enough due to unreasonable drug proportions and compatibility, and it is difficult to achieve a good therapeutic effect.

[0005] Therefore, providing a Chinese medicine extract for relieving cough, invigorating the kidneys and reducing fever in children and a preparation method thereof is an urgent problem to be solved by those skilled in the art. Summary of the invention

[0006] In view of this, the present invention provides a Chinese medicine extract for relieving cough, invigorating the kidneys and reducing fever in children, and a preparation method and application thereof.

[0007] In order to achieve the above object, the present invention first adopts the following technical solution:

[0008] A Chinese medicine extract for relieving cough, clearing the meridians and reducing fever in children, which is extracted from the following raw materials in parts by weight:

[0009] 2-5 parts of Xanthium sibiricum, 2-5 parts of Angelica dahurica, 2-5 parts of Patchouli, 2-5 parts of Perilla leaves, 2-5 parts of mulberry leaves, 1-3 parts of mint, 2-5 parts of honeysuckle, 1-3 parts of forsythia, 2-4 parts of burdock seeds, 1-3 parts of isatis indigotica, 1-3 parts of pinellia tuber, 1-3 parts of immature bitter orange, 2-4 parts of platycodon, 2-4 parts of coltsfoot flowers, 2-5 parts of loquat leaves, 2-5 parts of gynostemma pentaphyllum, 2-5 parts of stemona, 2-5 parts of cassia twig, 2-5 parts of kudzu root, 1-3 parts of elsholtzia, 2-5 parts of atractylodes, 1-3 parts of white cardamom, 2-5 parts of atractylodes, 2-4 parts of chicken's gizzard lining, and 1-3 parts of cloves.

[0010] The mass fraction of the raw materials is preferably:

[0011] 5 parts of Xanthium sibiricum Fructus, 5 parts of Angelica dahurica, 5 parts of Patchouli, 5 parts of Perilla Leaf, 5 parts of Morus Leaf, 3 parts of Menthus Fructus, 5 parts of Honeysuckle, 3 parts of Fructus Forsythiae, 4 parts of Fructus Arctii, 3 parts of Folium Isatidis, 3 parts of Pinellia Rhizoma, 3 parts of Fructus Aurantii Immaturus, 4 parts of Platycodon Grandiflorus, 4 parts of Flos Coltsfoot, 5 parts of Eriobotrya Japonicae, 5 parts of Gynostemma Pentaphyllum, 5 parts of Stemona, 5 parts of Cinnamomum Ramulus, 5 parts of Puerariae Radix, 3 parts of Elsholtzia, 5 parts of Atractylodes, 3 parts of White Cardamom, 5 parts of Atractylodes, 4 parts of Gallus Gizzard Bark, and 1 part of Clove.

[0012] In addition, the present application also claims protection for the preparation method of the Chinese medicine extract for relieving cough, clearing the meridians and reducing fever in children, which specifically comprises the following steps:

[0013] S1, weighing each Chinese medicinal material according to the mass ratio, and then soaking them in clean water for later use;

[0014] S2, putting the soaked raw materials into a casserole, boiling over high heat, then simmering over low heat, filtering to obtain the medicinal liquid for later use;

[0015] S3, putting the obtained medicinal solution into an evaporating dish, heating it over a low fire until the water is evaporated to dryness, and obtaining a Chinese medicinal extract.

[0016] The mass ratio of the Chinese medicinal materials and clean water in the soaking process described in S1 is 1:4;

[0017] The soaking time is 2 to 3 hours.

[0018] The slow cooking time over low heat described in S2 is 60 minutes.

[0019] In addition, the present application also requests protection for the use of the Chinese herbal extract or the Chinese herbal extract prepared by the preparation method in the preparation of drugs for relieving cough, clearing the orifices and reducing fever in children.

[0020] It can be seen from the above technical scheme that, compared with the prior art, the present invention discloses a Chinese medicine extract for relieving cough, clearing the orifices and reducing fever in children and its preparation method and application, wherein the effects of each Chinese medicine component used are as follows:

[0021] Xanthium sibiricum: It has the effects of dispelling wind and cold, clearing the nasal passages, removing rheumatism and relieving itching. It is mainly used to treat sinusitis, wind-cold headache, rheumatic pain, urticaria, eczema and scabies. Modern medical research shows that Xanthium sibiricum has antibacterial, anti-inflammatory and antitussive effects, and can treat respiratory diseases; 0.3ml / mouse oral administration of Xanthium sibiricum decoction has an antitussive effect on mice; small doses of tincture injection have a respiratory stimulant effect on frogs, while large doses have an inhibitory effect. In addition, Xanthium sibiricum also has the effects of lowering blood pressure and blood lipids.

[0022] Angelica dahurica: It has the effects of dispersing wind and dampness, relieving pain, reducing swelling and draining pus. It is used for colds and headaches, pain in the brow bone, nasal congestion, sinusitis, toothache, leucorrhea, and sores and swelling. Modern medical research shows that Angelica dahurica has antipyretic and analgesic effects. The decoction of Angelica dahurica has a significant antipyretic effect on the high fever animal model created by subcutaneous injection of peptone on the back of white rabbits. In addition, Angelica dahurica has multiple effects such as antibacterial and anti-inflammatory, antispasmodic, antihypertensive, anti-cancer, and anti-radiation. It also contains furanocoumarin compounds such as bergamotol, zanthoxylum toxin, and isoimperatorin B, which are photoactive and can treat skin diseases such as vitiligo.

[0023] Patchouli: It has the effects of aromatic turbidity, appetizing and stopping vomiting, and relieving heat. It is used for dampness and turbidity blocking the middle part of the body, abdominal distension and vomiting, summer dampness fatigue, chest tightness, cold dampness and summer heat, abdominal pain, vomiting and diarrhea, and sinusitis and headache. Modern medicine shows that patchouli has antibacterial and calcium antagonist effects. The patchouli ketone contained in it has a significant inhibitory effect on fungi such as white Candida albicans, Cryptococcus neoformans, and Rhizopus nigromaculus, and also has a certain inhibitory effect on bacteria such as type alpha hemolytic Streptococcus

[0024] Perilla leaf: Perilla contains perilla oil, the content of perilla aldehyde in the oil is 16.8%-22.6%, perilla alcohol accounts for 19.7%-23.1%, dihydroperilla alcohol content is 7.4%-8.5%, limonene accounts for about 2.8%, linalool accounts for 3.2%-4.6%, menthol 4.2%-20%, clove 4.6%-22.7%. In addition, it also contains oleanone, taurocholine, perilla ketone, isoperilla ketone, elemenesin, myristic ether, oleoyl amine and α-pinene. Perilla leaf has the effects of dispelling cold, promoting qi and harmonizing the stomach. It is used for colds, coughs, nausea, vomiting during pregnancy, and fish and crab poisoning.

[0025] Mulberry leaf: It has the effects of dispersing wind-heat, clearing the lungs and moistening dryness, clearing the liver and improving eyesight. It is used for wind-heat cold, lung heat and dry cough, dizziness and headache, red and blurred eyes. Modern medicine shows that mulberry leaf has antibacterial, anti-inflammatory and diuretic effects. Mulberry leaf decoction has a certain inhibitory effect on Staphylococcus aureus, beta-hemolytic Streptococcus, diphtheria and Escherichia coli in in vitro tests. In addition, it can also kill Leptospira. In addition, mulberry leaf also has the effects of relieving spasms, lowering blood sugar, lowering blood pressure and lowering blood lipids.

[0026] Mint: It has the functions of dispelling wind, dissipating heat, warding off filth, and detoxifying. It can treat exogenous wind-heat, headache, red eyes, sore throat, food stagnation and bloating, mouth sores, toothache, scabies, and eczema. Modern medical research shows that mint has a certain therapeutic effect on respiratory inflammation because it promotes the discharge of secretions, thereby removing mucus attached to the mucosa. Mint contains menthol and menthone, which have a contraction effect on isolated rabbit intestines, among which menthone has a stronger effect. In addition, mint can be used topically to treat symptoms such as headache, neuralgia, and itching.

[0027] Honeysuckle: It has the effect of clearing away heat and detoxifying. It is mainly used to treat fever caused by febrile diseases; dysentery caused by heat toxins; carbuncle, furuncle; throat paralysis and various infectious diseases. Modern medical research shows that honeysuckle contains cyclohexane hexol, flavonoids, inositol, saponin and tannin, which have broad-spectrum antibacterial effects and have a strong inhibitory effect on various pathogenic bacteria such as Staphylococcus aureus and Shigella dysenteriae. It also has an inhibitory effect on various pathogenic microorganisms such as leptospira, influenza virus and pathogenic mold. In addition, honeysuckle also has significant anti-inflammatory and antipyretic effects, and its water and wine extracts have a significant killing effect on experimental tumor cells.

[0028] Forsythia: It has the effects of clearing heat, detoxifying, dispersing masses and reducing swelling. It can treat fever, erysipelas, macules, carbuncle, ulcer, scrofula and urinary retention. Modern medical research shows that Forsythia has multiple effects such as anti-inflammatory, antibacterial, antiviral, antipyretic, analgesic, cardiotonic, diuretic, phosphodiesterase inhibition, blood pressure reduction, elastase activity inhibition and anti-endotoxin. In addition, it can clear heat, detoxify, reduce swelling and dissipate masses.

[0029] Burdock seeds: It has the effects of dispersing wind-heat, clearing lungs and clearing rashes, reducing swelling and detoxifying. It can treat wind-heat cough, sore throat, macules that do not clear up, itchy rashes, carbuncles and sores. Modern medical research shows that burdock seeds have antibacterial and antiviral effects, and have inhibitory effects on 9 pathogenic fungi such as Trichophyton cocoon, Trichophyton concentricum, and Trichophyton spp. In addition, burdock seeds also have multiple effects such as lowering blood sugar, lowering blood pressure, calcium antagonism, anti-tumor, anti-mutagenic, and treating kidney disease.

[0030] Folium isatidis: It has the effects of clearing away heat and detoxifying, cooling blood and removing spots. It is used for pathogenic heat entering the body, high fever and coma, spots and rashes, jaundice, heat dysentery, mumps, throat paralysis, erysipelas, and carbuncle. In clinical treatment, Folium isatidis is often used to treat epidemic encephalitis B, upper respiratory tract infection, influenza, measles pneumonia, chronic bronchitis, acute infectious hepatitis, leptospirosis, acute gastroenteritis, bacterial dysentery, acute appendicitis and other diseases.

[0031] Pinellia ternata: It has the effects of drying dampness and resolving phlegm; relieving adverse reactions and stopping vomiting; and eliminating lumps and dispersing lumps. It is mainly used to treat cough, asthma, and excessive sputum; vomiting and nausea; chest and abdominal distension, headache, and dizziness; restlessness at night; goiter, phlegm nucleus; carbuncle, swelling, and toxicity. Modern medical research shows that Pinellia ternata has obvious effects of relieving cough, vomiting, and inhibiting glandular secretion. In addition, it also has the effects of lowering blood pressure, coagulation, anti-cancer, and promoting cell division.

[0032] Zhishi: It has the effects of breaking up qi and eliminating stagnation; resolving phlegm and removing lumps. It is mainly used to treat stagnation of internal organs; fullness and pain in the lumps; constipation; heaviness after diarrhea; chest congestion; gastroptosis; uterine prolapse; rectal prolapse.

[0033] Platycodon grandiflorum: It has the effect of opening up the lung qi, removing phlegm and draining pus. It can treat exogenous cough, sore throat, lung abscess with pus, chest fullness and flank pain, and dysentery and abdominal pain. The platycodon grandiflorum saponins contained in platycodon grandiflorum have a direct stimulating effect on the oral, throat and gastric mucosa, and can reflexively promote the secretion of bronchial mucosa, making the sputum thinner and easier to discharge. Platycodon grandiflorum also has antitussive effects and can enhance anti-inflammatory and immune functions. Its anti-inflammatory effect is similar to that of aspirin. The water extract of platycodon grandiflorum can enhance the phagocytic function of macrophages, improve the bactericidal ability of neutrophils, and enhance the activity of lysozyme. In addition, platycodon grandiflorum has a certain preventive effect on stress ulcers. Platycodon grandiflorum crude saponins also have sedative, analgesic and antipyretic effects, and can also lower blood sugar and cholesterol levels and relax smooth muscles. Although platycodon grandiflorum saponins have a strong hemolytic effect, they will be decomposed and destroyed in the digestive tract after oral administration, thus losing their hemolytic activity.

[0034] Coltsfoot: It has the effects of moistening the lungs, lowering qi, resolving phlegm and relieving cough. It can treat cough, wheezing and throat paralysis. Modern medical research shows that coltsfoot has the effects of relieving cough, removing phlegm and slightly relieving asthma. Experiments have found that oral coltsfoot decoction has a significant antitussive effect on cough caused by injection of 1% iodine solution into the right pleural cavity of cats. Some areas in Eastern Europe also use coltsfoot or leaf preparations to treat tracheitis, pharyngitis and bronchial asthma. In addition, studies have shown that the alcohol-soluble ether soluble part of coltsfoot has a pressor effect, while the alcohol-soluble ether insoluble part has a hypotensive effect. The ether extract has an inhibitory effect on gastrointestinal smooth muscle in vivo or in vitro.

[0035] Loquat leaves: Contains amygdalin, ursolic acid, oleanolic acid, vitamins B1 and C, tannins, organic acids, sugars and other ingredients. It has the effects of clearing the lungs and stomach, lowering qi and resolving phlegm, and treating lung heat and phlegm cough, hemoptysis, epistaxis, and stomach heat and vomiting.

[0036] Gynostemma pentaphyllum: It has the effects of anti-inflammatory, detoxification, cough and expectoration. Modern medical research shows that it has the effects of improving immunity, lowering blood lipids, anti-tumor and delaying aging.

[0037] Stemona tuberosa: It has the functions of moistening the lungs and relieving cough, antibacterial and anti-inflammatory, and killing insects and lice. It is mainly used to treat new and chronic coughs, tuberculosis, whooping cough, pinworm disease, body lice, and scabies.

[0038] Cinnamon twig: It has the effects of sweating, relieving muscles, warming the meridians and unblocking blood vessels. It can treat wind-cold symptoms, sore shoulders, back and limbs, chest pain, phlegm and fluid retention, amenorrhea and abdominal masses. Cinnamon oil of cinnamon twig can dilate blood vessels and promote sweating. Cinnamaldehyde and sodium cinnamate can relieve fever, analgesia, sedation and anticonvulsant. Volatile oil can be anti-inflammatory and anti-allergic. In addition, studies have shown that it also has antibacterial and antiviral effects.

[0039] Pueraria root: It has the effects of raising yang and relieving muscles, clearing rashes and stopping diarrhea, and removing restlessness and stopping fever. It can treat typhoid fever, fever headache, stiff neck, restlessness and thirst, diarrhea, dysentery, macules that do not clear up, hypertension, angina pectoris, and deafness. Medical research shows that the soybean flavonoids in Pueraria root have antipyretic and antispasmodic effects. The flavonoids extracted from Pueraria root can increase the blood flow of the brain and coronary vessels, lower blood sugar, and have a certain effect on cardiovascular and cerebrovascular diseases.

[0040] Elsholtzia: It has the effects of sweating, dispelling exterior pathogens, harmonizing the middle and removing dampness. It is used for summer-heat cold, aversion to cold and fever, headache without sweating, abdominal pain, vomiting and diarrhea, and urinary difficulty. The volatile oil in Elsholtzia has a broad-spectrum antibacterial and bactericidal effect, and can directly inhibit influenza virus, and the volatile oil has a strong direct inhibitory effect on the spontaneous contraction activity of intestinal smooth muscle.

[0041] Atractylodes: It has the effects of drying dampness and strengthening the spleen, dispelling wind and cold, and improving eyesight. It is used for abdominal distension, diarrhea, edema, beriberi, rheumatism, colds, and night blindness. Modern medicine shows that it can adjust gastrointestinal motility, resist ulcers, calm, protect the liver, and inhibit bacteria. It can resist hypoxia, tumors, and promote bone calcification.

[0042] White cardamom: It has the functions of promoting qi, warming the stomach, digesting food and relieving fullness. It can treat qi stagnation, food stagnation, chest tightness, abdominal distension, belching, choking, vomiting, nausea and malaria.

[0043] Atractylodes macrocephala: It has the effects of tonifying the spleen, benefiting the stomach, drying dampness, harmonizing the middle and calming the fetus. It can treat weak spleen and stomach qi, loss of appetite, fatigue and lack of energy, bloating, diarrhea, phlegm and fluid retention, edema, jaundice, dampness, difficulty urinating, dizziness, spontaneous sweating, and restless fetus. Modern medicine shows that it has the effects of regulating gastrointestinal motility, anti-ulcer, enhancing basal immunity, anti-stress, enhancing hematopoiesis, inhibiting uterine contraction, diuresis, anti-oxidation, anti-aging, and anti-tumor.

[0044] Chicken gizzard lining: Contains gastric hormone, keratin, trace pepsin, amylase, multiple vitamins and trace elements, and 18 kinds of amino acids. It has the effects of strengthening the stomach and digestion, astringing sperm and stopping nocturnal emission. It is used for indigestion, vomiting and diarrhea, malnutrition in children, nocturnal enuresis, and nocturnal emission.

[0045] Clove: It has the effect of warming the spleen and stomach and reducing adverse qi. It is mainly used to treat stomach cold, vomiting, diarrhea, and abdominal pain. Medical research shows that it has the effects of antibacterial, antiparasitic, stomachic and analgesic.

[0046] It can be seen from the above technical solution that compared with the prior art, the present invention has the following beneficial effects:

[0047] The present invention provides a Chinese medicine extract for relieving cough, clearing the orifices and reducing fever in children, and a preparation method and application thereof. In the Chinese medicine formula, peppermint, honeysuckle, forsythia, burdock fruit, and isatis indigotica have the effects of clearing away heat and detoxifying, and can slow down the inflammatory reaction caused by heat toxins in the body. Perilla leaf, coltsfoot flower, loquat leaf, gynostemma pentaphyllum, and stemona have the effects of descending qi, promoting qi circulation, moistening the lungs and relieving cough. Angelica dahurica, forsythia, burdock fruit, ginger pinellia, immature bitter orange, platycodon, coltsfoot flower, piba leaf, and gynostemma pentaphyllum have the effects of removing phlegm and suppuration, dispersing nodules and reducing swelling, and help discharge phlegm and foreign matter in the respiratory tract. Xanthium sibiricum, angelica dahurica, and patchouli have the effects of clearing the nasal orifices and aromatically removing turbidity, and can relieve symptoms such as nasal congestion and runny nose caused by colds. Xanthium sibiricum, Angelica dahurica, Patchouli, Perilla leaf, Mulberry leaf, Mint, Burdock seed, Cinnamon twig, Pueraria root, Elsholtzia ciliata, Atractylodes lancea have the effects of dispelling wind and heat, sweating and relieving the symptoms, and dispelling wind and cold, and can relieve the symptoms of fever, chills, and alternating cold and heat caused by colds. Atractylodes lancea, white cardamom, Atractylodes macrocephala, chicken gizzard lining, and cloves have the effects of invigorating the stomach and digestion, drying dampness and strengthening the spleen, and can relieve the loss of appetite caused by colds. The rational compatibility and mutual synergy of the various drugs have the effects of relieving cough, clearing the orifices and reducing fever, and can effectively treat various symptoms caused by colds in children. DETAILED DESCRIPTION

[0048] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0049] Example 1

[0050] Weigh the Chinese medicinal raw materials according to the following mass ratio: 5 parts of Xanthium sibiricum, 5 parts of Angelica dahurica, 5 parts of Patchouli, 5 parts of Perilla Leaf, 5 parts of Mulberry Leaf, 3 parts of Mint, 5 parts of Honeysuckle, 3 parts of Forsythia suspensa, 4 parts of Arctium lappa, 3 parts of Isatis indigotica, 3 parts of Pinellia ternata, 3 parts of Citrus aurantium, 4 parts of Platycodon grandiflorum, 4 parts of Coltsfoot Flos, 5 parts of Loquat Leaf, 5 parts of Gynostemma Pentaphyllum, 5 parts of Stemona, 5 parts of Cinnamon Twig, 5 parts of Pueraria lobata, 3 parts of Elsholtzia, 5 parts of Atractylodes, 3 parts of White Cardamom, 5 parts of Atractylodes, 4 parts of Chicken Gizzard Stone, and 1 part of Clove.

[0051] Soak the medicine in clean water for 3 hours at a mass ratio of Chinese medicine raw materials to clean water of 1:4, and set aside.

[0052] Put the soaked raw materials into a casserole, boil over high heat, then simmer over low heat for 60 minutes, filter and obtain the medicinal liquid for later use.

[0053] The obtained medicinal solution is put into an evaporating dish and heated over low heat until the water is evaporated to dryness to obtain the Chinese medicine extract.

[0054] Clinical application experiment

[0055] 84 children with colds were selected and randomly divided into two groups, of which 42 cases in the experimental group were treated with the Chinese herbal extract described in the present application; and 42 cases in the control group were treated with Ganmaoling granules. The basic information of the two groups of children, such as gender and age, was statistically analyzed, and no statistical difference was found after comparison.

[0056] The treatment effects of the two groups of children were compared. If most of the symptoms such as fever and nasal congestion disappeared after 4 days, it was considered cured; if the symptoms such as fever and nasal congestion partially disappeared, it was considered effective; if the symptoms such as fever and nasal congestion did not disappear, it was considered ineffective.

[0057] The final treatment results are as follows:

[0058] Group Number of people Number of people cured Effective number of people Invalid number of people Total Effectiveness Experimental Group 42 14 23 5 88.10％ Control group 42 9 27 6 85.71％

[0059] The treatment results show that the various drugs in the present application are reasonably compatible and synergistic with each other, have the effects of relieving cough, clearing the orifices and reducing fever, and can effectively treat various symptoms caused by colds in children.

[0060] In the Chinese medicine prescription, peppermint, honeysuckle, forsythia, burdock, and isatis indigotica have the effects of clearing away heat and detoxifying, and can slow down the inflammatory reaction caused by heat toxins in the body. Perilla leaf, coltsfoot flower, loquat leaf, gynostemma pentaphyllum, and stemona have the effects of descending qi and promoting qi circulation, moistening the lungs and relieving cough. Angelica dahurica, forsythia, burdock fruit, ginger pinellia, immature bitter orange, platycodon, coltsfoot flower, piba leaf, and gynostemma pentaphyllum have the effects of expectorant and suppurative, dispersing nodules and reducing swelling, and help discharge phlegm and foreign bodies in the respiratory tract. Xanthium sibiricum, angelica dahurica, and patchouli have the effects of clearing the nasal passages and aromatically clearing turbidity, and can relieve the symptoms of nasal congestion and runny nose caused by colds. Xanthium sibiricum, Angelica dahurica, Patchouli, Perilla leaf, Mulberry leaf, Mint, Burdock seed, Cinnamon twig, Pueraria root, Elsholtzia ciliata, Atractylodes lancea have the effects of dispelling wind and heat, inducing sweating and relieving the symptoms of fever, chills, and alternating cold and heat caused by cold. Atractylodes lancea, White cardamom, Atractylodes macrocephala, Chicken gizzard lining, Clove have the effects of invigorating the stomach and digestion, drying dampness and strengthening the spleen, and can relieve the loss of appetite caused by cold.

[0061] The above description of the disclosed embodiments enables one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A Chinese herbal extract for relieving cough, clearing the orifices and reducing fever in children, characterized in that: It is extracted from the following raw materials by weight: 2-5 parts of Xanthium sibiricum, 2-5 parts of Angelica dahurica, 2-5 parts of Patchouli, 2-5 parts of Perilla leaves, 2-5 parts of mulberry leaves, 1-3 parts of mint, 2-5 parts of honeysuckle, 1-3 parts of forsythia, 2-4 parts of burdock seeds, 1-3 parts of isatis indigotica, 1-3 parts of pinellia tuber, 1-3 parts of immature bitter orange, 2-4 parts of platycodon, 2-4 parts of coltsfoot flowers, 2-5 parts of loquat leaves, 2-5 parts of gynostemma pentaphyllum, 2-5 parts of stemona, 2-5 parts of cassia twig, 2-5 parts of kudzu root, 1-3 parts of elsholtzia, 2-5 parts of atractylodes, 1-3 parts of white cardamom, 2-5 parts of atractylodes, 2-4 parts of chicken's gizzard lining, and 1-3 parts of cloves.

2. A Chinese medicine extract for relieving cough, invigorating the kidneys and reducing fever in children according to claim 1, characterized in that: The mass fraction of the raw materials is preferably: 5 parts of Xanthium sibiricum Fructus, 5 parts of Angelica dahurica, 5 parts of Patchouli, 5 parts of Perilla Leaf, 5 parts of Morus Leaf, 3 parts of Menthus Fructus, 5 parts of Honeysuckle, 3 parts of Fructus Forsythiae, 4 parts of Fructus Arctii, 3 parts of Folium Isatidis, 3 parts of Pinellia Rhizoma, 3 parts of Fructus Aurantii Immaturus, 4 parts of Platycodon Grandiflorus, 4 parts of Flos Coltsfoot, 5 parts of Eriobotrya Japonicae, 5 parts of Gynostemma Pentaphyllum, 5 parts of Stemona, 5 parts of Cinnamomum Ramulus, 5 parts of Puerariae Radix, 3 parts of Elsholtzia, 5 parts of Atractylodes, 3 parts of White Cardamom, 5 parts of Atractylodes, 4 parts of Gallus Gizzard Bark, and 1 part of Clove.

3. A method for preparing the Chinese medicine extract for relieving cough, invigorating the kidneys and reducing fever in children as claimed in any one of claims 1 to 2, characterized in that: The specific steps include: S1, weighing each Chinese medicinal material according to the mass ratio, and then soaking them in clean water for later use; S2, putting the soaked raw materials into a casserole, boiling over high heat, then simmering over low heat, filtering to obtain the medicinal liquid for later use; S3, putting the obtained medicinal solution into an evaporating dish, heating it over a low fire until the water is evaporated to dryness, and obtaining a Chinese medicinal extract.

4. The method for preparing a Chinese medicine extract for relieving cough, invigorating the kidneys and reducing fever in children according to claim 3, characterized in that: The mass ratio of the Chinese medicinal materials and clean water for soaking described in S1 is 1:

4.

5. The method for preparing a Chinese medicine extract for relieving cough, invigorating the kidneys and reducing fever in children according to claim 3, characterized in that: The soaking time in S1 is 2 to 3 hours.

6. The method for preparing a Chinese medicine extract for relieving cough, invigorating the kidneys and reducing fever in children according to claim 3, characterized in that: The slow cooking time over low heat described in S2 is 60 minutes.

7. Use of the Chinese herbal extract according to any one of claims 1 to 2 or the Chinese herbal extract prepared by the preparation method according to any one of claims 3 to 6 in the preparation of a drug for relieving cough, opening the orifices and reducing fever in children.